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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 39622

FusionGeneSummary for TRIT1_ABCA10

check button Fusion gene summary
Fusion gene informationFusion gene name: TRIT1_ABCA10
Fusion gene ID: 39622
HgeneTgene
Gene symbol

TRIT1

ABCA10

Gene ID

54802

10349

Gene nametRNA isopentenyltransferase 1ATP binding cassette subfamily A member 10
SynonymsCOXPD35|GRO1|IPPT|IPT|IPTase|MOD5|hGRO1EST698739
Cytomap

1p34.2

17q24.3

Type of geneprotein-codingprotein-coding
DescriptiontRNA dimethylallyltransferaseIPP transferaseisopentenyl-diphosphate:tRNA isopentenyltransferasetRNA dimethylallyltransferase, mitochondrialtRNA isopentenylpyrophosphate transferaseATP-binding cassette sub-family A member 10ATP-binding cassette A10ATP-binding cassette, sub-family A (ABC1), member 10
Modification date2018052320180523
UniProtAcc

Q9H3H1

Q8WWZ4

Ensembl transtripts involved in fusion geneENST00000441669, ENST00000316891, 
ENST00000372818, ENST00000491865, 
ENST00000541099, ENST00000537440, 
ENST00000537223, ENST00000545233, 
ENST00000544981, 		ENST00000416101, 
ENST00000269081, ENST00000432313, 
ENST00000519732, ENST00000423818, 
Fusion gene scores* DoF score5 X 1 X 3=153 X 3 X 3=27
# samples 33
** MAII scorelog2(3/15*10)=1
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: TRIT1 [Title/Abstract] AND ABCA10 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLIHCTCGA-PD-A5DF-01ATRIT1chr1

40348990

-ABCA10chr17

67193263

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000441669ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000441669ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000441669ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000441669ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000441669ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
In-frameENST00000316891ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000316891ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000316891ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000316891ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000316891ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
In-frameENST00000372818ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000372818ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000372818ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000372818ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000372818ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000491865ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000491865ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000491865ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000491865ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000491865ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000541099ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000541099ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000541099ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000541099ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000541099ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000537440ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000537440ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000537440ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000537440ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000537440ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000537223ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000537223ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000537223ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000537223ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000537223ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000545233ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000545233ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-3CDSENST00000545233ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000545233ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5UTR-intronENST00000545233ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-
In-frameENST00000544981ENST00000416101TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000544981ENST00000269081TRIT1chr1

40348990

-ABCA10chr17

67193263

-
Frame-shiftENST00000544981ENST00000432313TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000544981ENST00000519732TRIT1chr1

40348990

-ABCA10chr17

67193263

-
5CDS-intronENST00000544981ENST00000423818TRIT1chr1

40348990

-ABCA10chr17

67193263

-

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FusionProtFeatures for TRIT1_ABCA10


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TRIT1

Q9H3H1

ABCA10

Q8WWZ4

Probable transporter which may play a role in macrophagelipid homeostasis.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-11132_3758468RegionSubstrate binding
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-11032_3758442RegionSubstrate binding
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-1932_3758386RegionSubstrate binding
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-10401206_14403911544DomainABC transporter 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040391_6263911544DomainABC transporter 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-10391206_1440391449DomainABC transporter 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039391_626391449DomainABC transporter 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-051206_1440-13793DomainABC transporter 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05391_626-13793DomainABC transporter 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-10131206_1440391453DomainABC transporter 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013391_626391453DomainABC transporter 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-10401239_12463911544Nucleotide bindingATP 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040427_4343911544Nucleotide bindingATP 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-10391239_1246391449Nucleotide bindingATP 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039427_434391449Nucleotide bindingATP 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-051239_1246-13793Nucleotide bindingATP 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05427_434-13793Nucleotide bindingATP 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-10131239_1246391453Nucleotide bindingATP 2
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013427_434391453Nucleotide bindingATP 1
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-10401014_10343911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-10401046_10663911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-10401073_10933911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-10401113_11333911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040774_7943911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040890_9103911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040926_9463911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040985_10053911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-10391014_1034391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-10391046_1066391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-10391073_1093391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-10391113_1133391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039774_794391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039890_910391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039926_946391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039985_1005391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-051014_1034-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-051046_1066-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-051073_1093-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-051113_1133-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05135_155-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05185_205-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05210_230-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05240_260-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05264_284-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05310_330-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05774_794-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-0583_103-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05890_910-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05926_946-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000423818-05985_1005-13793TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-10131014_1034391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-10131046_1066391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-10131073_1093391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-10131113_1133391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013774_794391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013890_910391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013926_946391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013985_1005391453TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-111395_42558468Zinc fingerNote=Matrin-type
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-110395_42558442Zinc fingerNote=Matrin-type
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-19395_42558386Zinc fingerNote=Matrin-type
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040135_1553911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040185_2053911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040210_2303911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040240_2603911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040264_2843911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-1040310_3303911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000269081-104083_1033911544TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039135_155391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039185_205391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039210_230391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039240_260391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039264_284391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-1039310_330391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000416101-103983_103391449TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013135_155391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013185_205391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013210_230391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013240_260391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013264_284391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-1013310_330391453TransmembraneHelical
TgeneABCA10chr1:40348990chr17:67193263ENST00000432313-101383_103391453TransmembraneHelical


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FusionGeneSequence for TRIT1_ABCA10


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_TRIT1_ENST00000441669_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_58aa

>In-frame_TRIT1_ENST00000316891_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_58aa

>In-frame_TRIT1_ENST00000372818_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_58aa

>In-frame_TRIT1_ENST00000544981_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_58aa


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_TRIT1_ENST00000441669_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_174nt
ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG

>In-frame_TRIT1_ENST00000316891_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_174nt
ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG

>In-frame_TRIT1_ENST00000372818_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_174nt
ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG

>In-frame_TRIT1_ENST00000544981_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_174nt
ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG


* Fusion transcript sequences (Full-length transcript).
>In-frame_TRIT1_ENST00000441669_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_4275nt
ATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGTAGTGATTCTCGGG
GCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTCCATGCAGAATCAG
AAATGTTATAAAAGAATATAATGGAAAGACTGGAAAAGTAGAAGCATTGCAAGGCATATTTTTTGACATATATGAAGGACAGATCACTGC
AATACTTGGGCATAATGGAGCTGGTAAATCAACACTGCTAAACATTCTTAGTGGATTGTCTGTTTCTACAGAAGGTAAAAAGAATTATAA
TGGAATTAGACATGCAAAGCATTCAAGACATTATTGCTAAAAAATTAAGTGGTGGGCAGAAGAGAAAACTAACACTAGGGATTGCCATCT
TAGGAGATCCTCAGGTTTTGCTGCTAGATGAACCAACTGCTGGATTGGATCCCTTTTCAAGACACCGAGTGTGGAGCCTCCTGAAGGAGC
ATAAAGTAGACCGACTTATCCTCTTCAGTACCCAATTCATGGATGAGGCTGACATCTTGGCTGATAGGAAAGTATTTCTGTCTAATGGGA
AGTTGAAATGTGCAGGATCATCTTTGTTTCTGAAGCGAAAGTGGGGTATTGGATATCATTTAAGTTTACACAGGAATGAAATGTGTGACA
CAGAAAAAATCACATCCCTTATTAAGCAGCACATTCCTGATGCCAAGTTAACAACAGAAAGTGAAGAAAAACTTGTATATAGTTTGCCTT
TGGAAAAAACGAACAAATTTCCAGATCTTTACAGTGACCTTGATAAGTGTTCTGACCAGGGCATAAGGAATTATGCTGTTTCAGTGACAT
CTCTGAATGAAGTATTCTTGAACCTAGAAGGAAAATCAGCAATTGATGAACCAGATTTTGACATTGGGAAACAAGAGAAAATACATGTGA
CAAGAAATACTGGAGATGAGTCTGAAATGGAACAGGTTCTTTGTTCTCTTCCTGAAACAAGAAAGGCTGTCAGTAGTGCAGCTCTCTGGA
GACGACAAATCTATGCAGTGGCAACACTTCGCTTCTTAAAGTTAAGGCGTGAAAGGAGAGCTCTTTTGTGTTTGTTACTAGTACTTGGAA
TTGCTTTTATCCCCATCATTCTAGAGAAGATAATGTATAAAGTAACTCGTGAAACTCATTGTTGGGAGTTTTCACCCAGTATGTATTTCC
TTTCTCTGGAACAAATCCCGAAGACGCCTCTTACCAGCCTGTTAATCGTTAATAATACAGGATCAAATATTGAAGACCTCGTGCATTCAC
TGAAGTGTCAGGATATAGTTTTGGAAATAGATGACTTTAGAAACAGAAATGGCTCAGATGATCCCTCCTACAATGGAGCCATCATAGTGT
CTGGTGACCAGAAGGATTACAGATTTTCTGTTGCGTGTAATACCAAGAAATTGAATTGTTTTCCTGTTCTTATGGGAATTGTTAGCAATG
CCCTTATGGGAATTTTTAACTTCACGGAGCTTATTCAAATGGAGAGCACTTCATTTTCTCGTGATGACATAGTGCTGGATCTTGGTTTTA
TAGATGGGTCCATATTTTTGTTGTTGATCACAAACTGCGTTTCTCCTTTTATCGGCATGAGCAGCATCAGCGATTATAAAAAAAATGTTC
AATCCCAGTTATGGATTTCAGGCCTCTGGCCTTCAGCATACTGGTGTGGACAGGCTCTGGTGGACATTCCATTATACTTCTTGATTCTCT
TTTCAATACATTTAATTTACTACTTCATATTTCTGGGATTCCAGCTTTCATGGGAACTCATGTTTGTTTTGGTGGTATGCATAATTGGTT
GTGCAGTTTCTCTTATATTCCTCACATATGTGCTTTCATTCATCTTTCGCAAGTGGAGAAAAAATAATGGCTTTTGGTCTTTTGGCTTTT
TTATTATCTTAATATGTGTATCCACAATTATGGTATCAACTCAATATGAAAAACTCAACTTAATTTTGTGCATGATTTTCATACCTTCCT
TCACTTTGCTGGGGTATGTCATGTTATTGATCCAGCTCGACTTTATGAGAAACTTGGACAGTCTGGACAATAGAATAAATGAAGTCAATA
AAACCATTCTTTTAACAACCTTAATACCATACCTTCAGAGTGTTATTTTCCTTTTTGTCATAAGGTGTCTGGAAATGAAGTATGGAAATG
AAATAATGAATAAAGACCCAGTTTTCAGAATCTCTCCACGGAGTAGAGAAACTCATCCCAATCCGGAAGAGCCCGAAGAAGAAGATGAAG
ATGTTCAAGCTGAAAGAGTCCAAGCAGCAAATGCACTCACTGCTCCAAACTTGGAGGAGGAACCAGTCATAACTGCAAGCTGTTTACACA
AGGAATATTATGAGACAAAGAAAAGTTGCTTTTCAACAAGAAAGAAGAAAATAGCCATCAGAAATGTTTCCTTTTGTGTTAAAAAAGGTG
AAGTTTTGGGATTACTAGGACACAATGGAGCTGGTAAAAGTACTTCCATTAAAATGATAACTGGGTGCACAAAGCCAACTGCAGGAGTGG
TGGTGTTACAAGGCAGCAGAGCATCAGTAAGGCAACAGCATGACAACAGCCTCAAGTTCTTGGGGTACTGCCCTCAGGAGAACTCACTGT
GGCCCAAGCTTACAATGAAAGAGCACTTGGAGTTGTATGCAGCTGTGAAAGGACTGGGCAAAGAAGATGCTGCTCTCAGTATTTCACGAT
TGGTGGAAGCTCTTAAGCTCCAGGAACAACTTAAGGCTCCTGTGAAAACTCTATCAGAGGGAATAAAGAGAAAGCTGTGCTTTGTGCTGA
GCATCCTGGGGAACCCATCAGTGGTGCTTCTAGATGAGCCGTTCACCGGGATGGACCCCGAGGGGCAGCAGCAAATGTGGCAGATACTTC
AGGCTACCGTTAAAAACAAGGAGAGGGGCACCCTCTTGACCACCCATTACATGTCAGAGGCTGAGGCTGTGTGTGACCGTATGGCCATGA
TGGTGTCAGGAACGCTAAGGTGTATTGGTTCCATTCAACATCTGAAAAACAAGTTTGGTAGAGATTATTTACTAGAAATAAAAATGAAAG
AACCTACCCAGGTGGAAGCTCTCCACACAGAGATTTTGAAGCTTTTCCCACAGGCTGCTTGGCAGGAAAGATATTCCTCTTTAATGGCGT
ATAAGTTACCTGTGGAGGATGTCCACCCTCTATCTCGGGCCTTTTTCAAGTTAGAGGCGATGAAACAGACCTTCAACCTGGAGGAATACA
GCCTCTCTCAGGCTACCTTGGAGCAGGTATTCTTAGAACTCTGTAAAGAGCAGGAGCTGGGAAATGTTGATGATAAAATTGATACAACAG
TTGAATGGAAACTTCTCCCACAGGAAGACCCTTAAAATGAAGAACCTCCTAACATTCAATTTTAGGTCCTACTACATTGTTAGTTTCCAT
AATTCTACAAGAATGTTTCCTTTTACTTCAGTTAACAAAAGAAAACATTTAATAAACATTCAATAATGATTACAGTTTTCATTTTTAAAA
ATTTAGGATGAAGGAAACAAGGAAATATAGGGAAAAGTAGTAGACAAAATTAACAAAATCAGACATGTTATTCATCCCCAACATGGGTCT
ATTTTGTGCTTAAAAATAATTTAAAAATCATACAATATTAGGTTGGTTATCGGTTATTATCAATAAAGCTAACACTGAGAACATTTTACA
AATAAAAATATGAGGTTTTTAGCCTGAACTTCAAATGTATCAGCTATTTTTAAACATTATTTACTCGGATTCTAATTTAATGTGACATTG
ACTATAAGAAGGTCTGATAAACTGATGAAATGGCACAGCATAACATTTAATTATAATGACATTCTGATTATAAAATAAATGCATGTGAAT
TTTAGTACATATTGAAGTTATATGGAAGAAGATAGCCATAATCTGTAAGAAAGTACCGCAGTTAATATTTTCTTTAGCCAACTTATATTC
AATGTATTTTTTATGGATCCTTTTTCAAAGGTAGTATCAGTAGGCATAGTCATTTTCTGTATCTTTTCACCTCACAGTTCATGAACATTT
CCCATGTCATTATAGCACTTTTGTGTTATATAATTGCTGCATTAATGTTATAGCTGTATTGATGTAATACCAGAGTTGTTACGTTCGGGT

>In-frame_TRIT1_ENST00000316891_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_4290nt
GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT
GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC
TCCATGCAGAATCAGAAATGTTATAAAAGAATATAATGGAAAGACTGGAAAAGTAGAAGCATTGCAAGGCATATTTTTTGACATATATGA
AGGACAGATCACTGCAATACTTGGGCATAATGGAGCTGGTAAATCAACACTGCTAAACATTCTTAGTGGATTGTCTGTTTCTACAGAAGG
TAAAAAGAATTATAATGGAATTAGACATGCAAAGCATTCAAGACATTATTGCTAAAAAATTAAGTGGTGGGCAGAAGAGAAAACTAACAC
TAGGGATTGCCATCTTAGGAGATCCTCAGGTTTTGCTGCTAGATGAACCAACTGCTGGATTGGATCCCTTTTCAAGACACCGAGTGTGGA
GCCTCCTGAAGGAGCATAAAGTAGACCGACTTATCCTCTTCAGTACCCAATTCATGGATGAGGCTGACATCTTGGCTGATAGGAAAGTAT
TTCTGTCTAATGGGAAGTTGAAATGTGCAGGATCATCTTTGTTTCTGAAGCGAAAGTGGGGTATTGGATATCATTTAAGTTTACACAGGA
ATGAAATGTGTGACACAGAAAAAATCACATCCCTTATTAAGCAGCACATTCCTGATGCCAAGTTAACAACAGAAAGTGAAGAAAAACTTG
TATATAGTTTGCCTTTGGAAAAAACGAACAAATTTCCAGATCTTTACAGTGACCTTGATAAGTGTTCTGACCAGGGCATAAGGAATTATG
CTGTTTCAGTGACATCTCTGAATGAAGTATTCTTGAACCTAGAAGGAAAATCAGCAATTGATGAACCAGATTTTGACATTGGGAAACAAG
AGAAAATACATGTGACAAGAAATACTGGAGATGAGTCTGAAATGGAACAGGTTCTTTGTTCTCTTCCTGAAACAAGAAAGGCTGTCAGTA
GTGCAGCTCTCTGGAGACGACAAATCTATGCAGTGGCAACACTTCGCTTCTTAAAGTTAAGGCGTGAAAGGAGAGCTCTTTTGTGTTTGT
TACTAGTACTTGGAATTGCTTTTATCCCCATCATTCTAGAGAAGATAATGTATAAAGTAACTCGTGAAACTCATTGTTGGGAGTTTTCAC
CCAGTATGTATTTCCTTTCTCTGGAACAAATCCCGAAGACGCCTCTTACCAGCCTGTTAATCGTTAATAATACAGGATCAAATATTGAAG
ACCTCGTGCATTCACTGAAGTGTCAGGATATAGTTTTGGAAATAGATGACTTTAGAAACAGAAATGGCTCAGATGATCCCTCCTACAATG
GAGCCATCATAGTGTCTGGTGACCAGAAGGATTACAGATTTTCTGTTGCGTGTAATACCAAGAAATTGAATTGTTTTCCTGTTCTTATGG
GAATTGTTAGCAATGCCCTTATGGGAATTTTTAACTTCACGGAGCTTATTCAAATGGAGAGCACTTCATTTTCTCGTGATGACATAGTGC
TGGATCTTGGTTTTATAGATGGGTCCATATTTTTGTTGTTGATCACAAACTGCGTTTCTCCTTTTATCGGCATGAGCAGCATCAGCGATT
ATAAAAAAAATGTTCAATCCCAGTTATGGATTTCAGGCCTCTGGCCTTCAGCATACTGGTGTGGACAGGCTCTGGTGGACATTCCATTAT
ACTTCTTGATTCTCTTTTCAATACATTTAATTTACTACTTCATATTTCTGGGATTCCAGCTTTCATGGGAACTCATGTTTGTTTTGGTGG
TATGCATAATTGGTTGTGCAGTTTCTCTTATATTCCTCACATATGTGCTTTCATTCATCTTTCGCAAGTGGAGAAAAAATAATGGCTTTT
GGTCTTTTGGCTTTTTTATTATCTTAATATGTGTATCCACAATTATGGTATCAACTCAATATGAAAAACTCAACTTAATTTTGTGCATGA
TTTTCATACCTTCCTTCACTTTGCTGGGGTATGTCATGTTATTGATCCAGCTCGACTTTATGAGAAACTTGGACAGTCTGGACAATAGAA
TAAATGAAGTCAATAAAACCATTCTTTTAACAACCTTAATACCATACCTTCAGAGTGTTATTTTCCTTTTTGTCATAAGGTGTCTGGAAA
TGAAGTATGGAAATGAAATAATGAATAAAGACCCAGTTTTCAGAATCTCTCCACGGAGTAGAGAAACTCATCCCAATCCGGAAGAGCCCG
AAGAAGAAGATGAAGATGTTCAAGCTGAAAGAGTCCAAGCAGCAAATGCACTCACTGCTCCAAACTTGGAGGAGGAACCAGTCATAACTG
CAAGCTGTTTACACAAGGAATATTATGAGACAAAGAAAAGTTGCTTTTCAACAAGAAAGAAGAAAATAGCCATCAGAAATGTTTCCTTTT
GTGTTAAAAAAGGTGAAGTTTTGGGATTACTAGGACACAATGGAGCTGGTAAAAGTACTTCCATTAAAATGATAACTGGGTGCACAAAGC
CAACTGCAGGAGTGGTGGTGTTACAAGGCAGCAGAGCATCAGTAAGGCAACAGCATGACAACAGCCTCAAGTTCTTGGGGTACTGCCCTC
AGGAGAACTCACTGTGGCCCAAGCTTACAATGAAAGAGCACTTGGAGTTGTATGCAGCTGTGAAAGGACTGGGCAAAGAAGATGCTGCTC
TCAGTATTTCACGATTGGTGGAAGCTCTTAAGCTCCAGGAACAACTTAAGGCTCCTGTGAAAACTCTATCAGAGGGAATAAAGAGAAAGC
TGTGCTTTGTGCTGAGCATCCTGGGGAACCCATCAGTGGTGCTTCTAGATGAGCCGTTCACCGGGATGGACCCCGAGGGGCAGCAGCAAA
TGTGGCAGATACTTCAGGCTACCGTTAAAAACAAGGAGAGGGGCACCCTCTTGACCACCCATTACATGTCAGAGGCTGAGGCTGTGTGTG
ACCGTATGGCCATGATGGTGTCAGGAACGCTAAGGTGTATTGGTTCCATTCAACATCTGAAAAACAAGTTTGGTAGAGATTATTTACTAG
AAATAAAAATGAAAGAACCTACCCAGGTGGAAGCTCTCCACACAGAGATTTTGAAGCTTTTCCCACAGGCTGCTTGGCAGGAAAGATATT
CCTCTTTAATGGCGTATAAGTTACCTGTGGAGGATGTCCACCCTCTATCTCGGGCCTTTTTCAAGTTAGAGGCGATGAAACAGACCTTCA
ACCTGGAGGAATACAGCCTCTCTCAGGCTACCTTGGAGCAGGTATTCTTAGAACTCTGTAAAGAGCAGGAGCTGGGAAATGTTGATGATA
AAATTGATACAACAGTTGAATGGAAACTTCTCCCACAGGAAGACCCTTAAAATGAAGAACCTCCTAACATTCAATTTTAGGTCCTACTAC
ATTGTTAGTTTCCATAATTCTACAAGAATGTTTCCTTTTACTTCAGTTAACAAAAGAAAACATTTAATAAACATTCAATAATGATTACAG
TTTTCATTTTTAAAAATTTAGGATGAAGGAAACAAGGAAATATAGGGAAAAGTAGTAGACAAAATTAACAAAATCAGACATGTTATTCAT
CCCCAACATGGGTCTATTTTGTGCTTAAAAATAATTTAAAAATCATACAATATTAGGTTGGTTATCGGTTATTATCAATAAAGCTAACAC
TGAGAACATTTTACAAATAAAAATATGAGGTTTTTAGCCTGAACTTCAAATGTATCAGCTATTTTTAAACATTATTTACTCGGATTCTAA
TTTAATGTGACATTGACTATAAGAAGGTCTGATAAACTGATGAAATGGCACAGCATAACATTTAATTATAATGACATTCTGATTATAAAA
TAAATGCATGTGAATTTTAGTACATATTGAAGTTATATGGAAGAAGATAGCCATAATCTGTAAGAAAGTACCGCAGTTAATATTTTCTTT
AGCCAACTTATATTCAATGTATTTTTTATGGATCCTTTTTCAAAGGTAGTATCAGTAGGCATAGTCATTTTCTGTATCTTTTCACCTCAC
AGTTCATGAACATTTCCCATGTCATTATAGCACTTTTGTGTTATATAATTGCTGCATTAATGTTATAGCTGTATTGATGTAATACCAGAG

>In-frame_TRIT1_ENST00000372818_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_4290nt
GCAGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTT
GTAGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGAC
TCCATGCAGAATCAGAAATGTTATAAAAGAATATAATGGAAAGACTGGAAAAGTAGAAGCATTGCAAGGCATATTTTTTGACATATATGA
AGGACAGATCACTGCAATACTTGGGCATAATGGAGCTGGTAAATCAACACTGCTAAACATTCTTAGTGGATTGTCTGTTTCTACAGAAGG
TAAAAAGAATTATAATGGAATTAGACATGCAAAGCATTCAAGACATTATTGCTAAAAAATTAAGTGGTGGGCAGAAGAGAAAACTAACAC
TAGGGATTGCCATCTTAGGAGATCCTCAGGTTTTGCTGCTAGATGAACCAACTGCTGGATTGGATCCCTTTTCAAGACACCGAGTGTGGA
GCCTCCTGAAGGAGCATAAAGTAGACCGACTTATCCTCTTCAGTACCCAATTCATGGATGAGGCTGACATCTTGGCTGATAGGAAAGTAT
TTCTGTCTAATGGGAAGTTGAAATGTGCAGGATCATCTTTGTTTCTGAAGCGAAAGTGGGGTATTGGATATCATTTAAGTTTACACAGGA
ATGAAATGTGTGACACAGAAAAAATCACATCCCTTATTAAGCAGCACATTCCTGATGCCAAGTTAACAACAGAAAGTGAAGAAAAACTTG
TATATAGTTTGCCTTTGGAAAAAACGAACAAATTTCCAGATCTTTACAGTGACCTTGATAAGTGTTCTGACCAGGGCATAAGGAATTATG
CTGTTTCAGTGACATCTCTGAATGAAGTATTCTTGAACCTAGAAGGAAAATCAGCAATTGATGAACCAGATTTTGACATTGGGAAACAAG
AGAAAATACATGTGACAAGAAATACTGGAGATGAGTCTGAAATGGAACAGGTTCTTTGTTCTCTTCCTGAAACAAGAAAGGCTGTCAGTA
GTGCAGCTCTCTGGAGACGACAAATCTATGCAGTGGCAACACTTCGCTTCTTAAAGTTAAGGCGTGAAAGGAGAGCTCTTTTGTGTTTGT
TACTAGTACTTGGAATTGCTTTTATCCCCATCATTCTAGAGAAGATAATGTATAAAGTAACTCGTGAAACTCATTGTTGGGAGTTTTCAC
CCAGTATGTATTTCCTTTCTCTGGAACAAATCCCGAAGACGCCTCTTACCAGCCTGTTAATCGTTAATAATACAGGATCAAATATTGAAG
ACCTCGTGCATTCACTGAAGTGTCAGGATATAGTTTTGGAAATAGATGACTTTAGAAACAGAAATGGCTCAGATGATCCCTCCTACAATG
GAGCCATCATAGTGTCTGGTGACCAGAAGGATTACAGATTTTCTGTTGCGTGTAATACCAAGAAATTGAATTGTTTTCCTGTTCTTATGG
GAATTGTTAGCAATGCCCTTATGGGAATTTTTAACTTCACGGAGCTTATTCAAATGGAGAGCACTTCATTTTCTCGTGATGACATAGTGC
TGGATCTTGGTTTTATAGATGGGTCCATATTTTTGTTGTTGATCACAAACTGCGTTTCTCCTTTTATCGGCATGAGCAGCATCAGCGATT
ATAAAAAAAATGTTCAATCCCAGTTATGGATTTCAGGCCTCTGGCCTTCAGCATACTGGTGTGGACAGGCTCTGGTGGACATTCCATTAT
ACTTCTTGATTCTCTTTTCAATACATTTAATTTACTACTTCATATTTCTGGGATTCCAGCTTTCATGGGAACTCATGTTTGTTTTGGTGG
TATGCATAATTGGTTGTGCAGTTTCTCTTATATTCCTCACATATGTGCTTTCATTCATCTTTCGCAAGTGGAGAAAAAATAATGGCTTTT
GGTCTTTTGGCTTTTTTATTATCTTAATATGTGTATCCACAATTATGGTATCAACTCAATATGAAAAACTCAACTTAATTTTGTGCATGA
TTTTCATACCTTCCTTCACTTTGCTGGGGTATGTCATGTTATTGATCCAGCTCGACTTTATGAGAAACTTGGACAGTCTGGACAATAGAA
TAAATGAAGTCAATAAAACCATTCTTTTAACAACCTTAATACCATACCTTCAGAGTGTTATTTTCCTTTTTGTCATAAGGTGTCTGGAAA
TGAAGTATGGAAATGAAATAATGAATAAAGACCCAGTTTTCAGAATCTCTCCACGGAGTAGAGAAACTCATCCCAATCCGGAAGAGCCCG
AAGAAGAAGATGAAGATGTTCAAGCTGAAAGAGTCCAAGCAGCAAATGCACTCACTGCTCCAAACTTGGAGGAGGAACCAGTCATAACTG
CAAGCTGTTTACACAAGGAATATTATGAGACAAAGAAAAGTTGCTTTTCAACAAGAAAGAAGAAAATAGCCATCAGAAATGTTTCCTTTT
GTGTTAAAAAAGGTGAAGTTTTGGGATTACTAGGACACAATGGAGCTGGTAAAAGTACTTCCATTAAAATGATAACTGGGTGCACAAAGC
CAACTGCAGGAGTGGTGGTGTTACAAGGCAGCAGAGCATCAGTAAGGCAACAGCATGACAACAGCCTCAAGTTCTTGGGGTACTGCCCTC
AGGAGAACTCACTGTGGCCCAAGCTTACAATGAAAGAGCACTTGGAGTTGTATGCAGCTGTGAAAGGACTGGGCAAAGAAGATGCTGCTC
TCAGTATTTCACGATTGGTGGAAGCTCTTAAGCTCCAGGAACAACTTAAGGCTCCTGTGAAAACTCTATCAGAGGGAATAAAGAGAAAGC
TGTGCTTTGTGCTGAGCATCCTGGGGAACCCATCAGTGGTGCTTCTAGATGAGCCGTTCACCGGGATGGACCCCGAGGGGCAGCAGCAAA
TGTGGCAGATACTTCAGGCTACCGTTAAAAACAAGGAGAGGGGCACCCTCTTGACCACCCATTACATGTCAGAGGCTGAGGCTGTGTGTG
ACCGTATGGCCATGATGGTGTCAGGAACGCTAAGGTGTATTGGTTCCATTCAACATCTGAAAAACAAGTTTGGTAGAGATTATTTACTAG
AAATAAAAATGAAAGAACCTACCCAGGTGGAAGCTCTCCACACAGAGATTTTGAAGCTTTTCCCACAGGCTGCTTGGCAGGAAAGATATT
CCTCTTTAATGGCGTATAAGTTACCTGTGGAGGATGTCCACCCTCTATCTCGGGCCTTTTTCAAGTTAGAGGCGATGAAACAGACCTTCA
ACCTGGAGGAATACAGCCTCTCTCAGGCTACCTTGGAGCAGGTATTCTTAGAACTCTGTAAAGAGCAGGAGCTGGGAAATGTTGATGATA
AAATTGATACAACAGTTGAATGGAAACTTCTCCCACAGGAAGACCCTTAAAATGAAGAACCTCCTAACATTCAATTTTAGGTCCTACTAC
ATTGTTAGTTTCCATAATTCTACAAGAATGTTTCCTTTTACTTCAGTTAACAAAAGAAAACATTTAATAAACATTCAATAATGATTACAG
TTTTCATTTTTAAAAATTTAGGATGAAGGAAACAAGGAAATATAGGGAAAAGTAGTAGACAAAATTAACAAAATCAGACATGTTATTCAT
CCCCAACATGGGTCTATTTTGTGCTTAAAAATAATTTAAAAATCATACAATATTAGGTTGGTTATCGGTTATTATCAATAAAGCTAACAC
TGAGAACATTTTACAAATAAAAATATGAGGTTTTTAGCCTGAACTTCAAATGTATCAGCTATTTTTAAACATTATTTACTCGGATTCTAA
TTTAATGTGACATTGACTATAAGAAGGTCTGATAAACTGATGAAATGGCACAGCATAACATTTAATTATAATGACATTCTGATTATAAAA
TAAATGCATGTGAATTTTAGTACATATTGAAGTTATATGGAAGAAGATAGCCATAATCTGTAAGAAAGTACCGCAGTTAATATTTTCTTT
AGCCAACTTATATTCAATGTATTTTTTATGGATCCTTTTTCAAAGGTAGTATCAGTAGGCATAGTCATTTTCTGTATCTTTTCACCTCAC
AGTTCATGAACATTTCCCATGTCATTATAGCACTTTTGTGTTATATAATTGCTGCATTAATGTTATAGCTGTATTGATGTAATACCAGAG

>In-frame_TRIT1_ENST00000544981_chr1_40348990_-_ABCA10_ENST00000416101_chr17_67193263_-_4288nt
AGACTGCCATAAGATGGCGTCCGTGGCGGCTGCACGAGCAGTTCCCGTGGGCAGTGGGCTCAGGGGCCTGCAACGGACCCTACCTCTTGT
AGTGATTCTCGGGGCCACGGGCACCGGCAAATCCACGCTGGCGTTGCAGCTAGGCCAGCGGCTCGGCGGTGAGATCGTCAGCGCTGACTC
CATGCAGAATCAGAAATGTTATAAAAGAATATAATGGAAAGACTGGAAAAGTAGAAGCATTGCAAGGCATATTTTTTGACATATATGAAG
GACAGATCACTGCAATACTTGGGCATAATGGAGCTGGTAAATCAACACTGCTAAACATTCTTAGTGGATTGTCTGTTTCTACAGAAGGTA
AAAAGAATTATAATGGAATTAGACATGCAAAGCATTCAAGACATTATTGCTAAAAAATTAAGTGGTGGGCAGAAGAGAAAACTAACACTA
GGGATTGCCATCTTAGGAGATCCTCAGGTTTTGCTGCTAGATGAACCAACTGCTGGATTGGATCCCTTTTCAAGACACCGAGTGTGGAGC
CTCCTGAAGGAGCATAAAGTAGACCGACTTATCCTCTTCAGTACCCAATTCATGGATGAGGCTGACATCTTGGCTGATAGGAAAGTATTT
CTGTCTAATGGGAAGTTGAAATGTGCAGGATCATCTTTGTTTCTGAAGCGAAAGTGGGGTATTGGATATCATTTAAGTTTACACAGGAAT
GAAATGTGTGACACAGAAAAAATCACATCCCTTATTAAGCAGCACATTCCTGATGCCAAGTTAACAACAGAAAGTGAAGAAAAACTTGTA
TATAGTTTGCCTTTGGAAAAAACGAACAAATTTCCAGATCTTTACAGTGACCTTGATAAGTGTTCTGACCAGGGCATAAGGAATTATGCT
GTTTCAGTGACATCTCTGAATGAAGTATTCTTGAACCTAGAAGGAAAATCAGCAATTGATGAACCAGATTTTGACATTGGGAAACAAGAG
AAAATACATGTGACAAGAAATACTGGAGATGAGTCTGAAATGGAACAGGTTCTTTGTTCTCTTCCTGAAACAAGAAAGGCTGTCAGTAGT
GCAGCTCTCTGGAGACGACAAATCTATGCAGTGGCAACACTTCGCTTCTTAAAGTTAAGGCGTGAAAGGAGAGCTCTTTTGTGTTTGTTA
CTAGTACTTGGAATTGCTTTTATCCCCATCATTCTAGAGAAGATAATGTATAAAGTAACTCGTGAAACTCATTGTTGGGAGTTTTCACCC
AGTATGTATTTCCTTTCTCTGGAACAAATCCCGAAGACGCCTCTTACCAGCCTGTTAATCGTTAATAATACAGGATCAAATATTGAAGAC
CTCGTGCATTCACTGAAGTGTCAGGATATAGTTTTGGAAATAGATGACTTTAGAAACAGAAATGGCTCAGATGATCCCTCCTACAATGGA
GCCATCATAGTGTCTGGTGACCAGAAGGATTACAGATTTTCTGTTGCGTGTAATACCAAGAAATTGAATTGTTTTCCTGTTCTTATGGGA
ATTGTTAGCAATGCCCTTATGGGAATTTTTAACTTCACGGAGCTTATTCAAATGGAGAGCACTTCATTTTCTCGTGATGACATAGTGCTG
GATCTTGGTTTTATAGATGGGTCCATATTTTTGTTGTTGATCACAAACTGCGTTTCTCCTTTTATCGGCATGAGCAGCATCAGCGATTAT
AAAAAAAATGTTCAATCCCAGTTATGGATTTCAGGCCTCTGGCCTTCAGCATACTGGTGTGGACAGGCTCTGGTGGACATTCCATTATAC
TTCTTGATTCTCTTTTCAATACATTTAATTTACTACTTCATATTTCTGGGATTCCAGCTTTCATGGGAACTCATGTTTGTTTTGGTGGTA
TGCATAATTGGTTGTGCAGTTTCTCTTATATTCCTCACATATGTGCTTTCATTCATCTTTCGCAAGTGGAGAAAAAATAATGGCTTTTGG
TCTTTTGGCTTTTTTATTATCTTAATATGTGTATCCACAATTATGGTATCAACTCAATATGAAAAACTCAACTTAATTTTGTGCATGATT
TTCATACCTTCCTTCACTTTGCTGGGGTATGTCATGTTATTGATCCAGCTCGACTTTATGAGAAACTTGGACAGTCTGGACAATAGAATA
AATGAAGTCAATAAAACCATTCTTTTAACAACCTTAATACCATACCTTCAGAGTGTTATTTTCCTTTTTGTCATAAGGTGTCTGGAAATG
AAGTATGGAAATGAAATAATGAATAAAGACCCAGTTTTCAGAATCTCTCCACGGAGTAGAGAAACTCATCCCAATCCGGAAGAGCCCGAA
GAAGAAGATGAAGATGTTCAAGCTGAAAGAGTCCAAGCAGCAAATGCACTCACTGCTCCAAACTTGGAGGAGGAACCAGTCATAACTGCA
AGCTGTTTACACAAGGAATATTATGAGACAAAGAAAAGTTGCTTTTCAACAAGAAAGAAGAAAATAGCCATCAGAAATGTTTCCTTTTGT
GTTAAAAAAGGTGAAGTTTTGGGATTACTAGGACACAATGGAGCTGGTAAAAGTACTTCCATTAAAATGATAACTGGGTGCACAAAGCCA
ACTGCAGGAGTGGTGGTGTTACAAGGCAGCAGAGCATCAGTAAGGCAACAGCATGACAACAGCCTCAAGTTCTTGGGGTACTGCCCTCAG
GAGAACTCACTGTGGCCCAAGCTTACAATGAAAGAGCACTTGGAGTTGTATGCAGCTGTGAAAGGACTGGGCAAAGAAGATGCTGCTCTC
AGTATTTCACGATTGGTGGAAGCTCTTAAGCTCCAGGAACAACTTAAGGCTCCTGTGAAAACTCTATCAGAGGGAATAAAGAGAAAGCTG
TGCTTTGTGCTGAGCATCCTGGGGAACCCATCAGTGGTGCTTCTAGATGAGCCGTTCACCGGGATGGACCCCGAGGGGCAGCAGCAAATG
TGGCAGATACTTCAGGCTACCGTTAAAAACAAGGAGAGGGGCACCCTCTTGACCACCCATTACATGTCAGAGGCTGAGGCTGTGTGTGAC
CGTATGGCCATGATGGTGTCAGGAACGCTAAGGTGTATTGGTTCCATTCAACATCTGAAAAACAAGTTTGGTAGAGATTATTTACTAGAA
ATAAAAATGAAAGAACCTACCCAGGTGGAAGCTCTCCACACAGAGATTTTGAAGCTTTTCCCACAGGCTGCTTGGCAGGAAAGATATTCC
TCTTTAATGGCGTATAAGTTACCTGTGGAGGATGTCCACCCTCTATCTCGGGCCTTTTTCAAGTTAGAGGCGATGAAACAGACCTTCAAC
CTGGAGGAATACAGCCTCTCTCAGGCTACCTTGGAGCAGGTATTCTTAGAACTCTGTAAAGAGCAGGAGCTGGGAAATGTTGATGATAAA
ATTGATACAACAGTTGAATGGAAACTTCTCCCACAGGAAGACCCTTAAAATGAAGAACCTCCTAACATTCAATTTTAGGTCCTACTACAT
TGTTAGTTTCCATAATTCTACAAGAATGTTTCCTTTTACTTCAGTTAACAAAAGAAAACATTTAATAAACATTCAATAATGATTACAGTT
TTCATTTTTAAAAATTTAGGATGAAGGAAACAAGGAAATATAGGGAAAAGTAGTAGACAAAATTAACAAAATCAGACATGTTATTCATCC
CCAACATGGGTCTATTTTGTGCTTAAAAATAATTTAAAAATCATACAATATTAGGTTGGTTATCGGTTATTATCAATAAAGCTAACACTG
AGAACATTTTACAAATAAAAATATGAGGTTTTTAGCCTGAACTTCAAATGTATCAGCTATTTTTAAACATTATTTACTCGGATTCTAATT
TAATGTGACATTGACTATAAGAAGGTCTGATAAACTGATGAAATGGCACAGCATAACATTTAATTATAATGACATTCTGATTATAAAATA
AATGCATGTGAATTTTAGTACATATTGAAGTTATATGGAAGAAGATAGCCATAATCTGTAAGAAAGTACCGCAGTTAATATTTTCTTTAG
CCAACTTATATTCAATGTATTTTTTATGGATCCTTTTTCAAAGGTAGTATCAGTAGGCATAGTCATTTTCTGTATCTTTTCACCTCACAG
TTCATGAACATTTCCCATGTCATTATAGCACTTTTGTGTTATATAATTGCTGCATTAATGTTATAGCTGTATTGATGTAATACCAGAGTT


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FusionGenePPI for TRIT1_ABCA10


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
TRIT1HGH1, SMYD3, SHE, ANKS1AABCA10CUL4A, COPS5


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-11155_5858468substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-11055_5858442substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-1955_5858386substrate tRNA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-111233_25558468isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-110233_25558442isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-19233_25558386isopentenylpyrophosphate transferase
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-111183_18758468substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-111281_28358468substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-111313_33158468substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000316891-111323_33058468substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-110183_18758442substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-110281_28358442substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-110313_33158442substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000372818-110323_33058442substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-19183_18758386substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-19281_28358386substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-19313_33158386substrate tRNA
HgeneTRIT1chr1:40348990chr17:67193263ENST00000441669-19323_33058386substrate tRNA


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for TRIT1_ABCA10


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TRIT1_ABCA10


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTRIT1C0032927Precancerous Conditions1CTD_human
TgeneABCA10C0009404Colorectal Neoplasms1CTD_human