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Fusion gene ID: 39552 |
FusionGeneSummary for TRIM55_PSMG3 |
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Fusion gene information | Fusion gene name: TRIM55_PSMG3 | Fusion gene ID: 39552 | Hgene | Tgene | Gene symbol | TRIM55 | PSMG3 | Gene ID | 84675 | 84262 |
Gene name | tripartite motif containing 55 | proteasome assembly chaperone 3 | |
Synonyms | MURF-2|RNF29|muRF2 | C7orf48|PAC3 | |
Cytomap | 8q13.1 | 7p22.3 | |
Type of gene | protein-coding | protein-coding | |
Description | tripartite motif-containing protein 55muscle specific ring finger 2muscle-specific RING finger protein 2ring finger protein 29 | proteasome assembly chaperone 3PAC-3hPAC3proteasome (prosome, macropain) assembly chaperone 3proteasome assembling chaperone 3 | |
Modification date | 20180519 | 20180523 | |
UniProtAcc | Q9BYV6 | Q9BT73 | |
Ensembl transtripts involved in fusion gene | ENST00000353317, ENST00000315962, ENST00000276573, ENST00000350034, | ENST00000288607, ENST00000404674, ENST00000252329, | |
Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 2 X 2=8 |
# samples | 1 | 2 | |
** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/8*10)=1.32192809488736 | |
Context | PubMed: TRIM55 [Title/Abstract] AND PSMG3 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AK056594 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3UTR | ENST00000353317 | ENST00000288607 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-3UTR | ENST00000353317 | ENST00000404674 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-intron | ENST00000353317 | ENST00000252329 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-3UTR | ENST00000315962 | ENST00000288607 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-3UTR | ENST00000315962 | ENST00000404674 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-intron | ENST00000315962 | ENST00000252329 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-3UTR | ENST00000276573 | ENST00000288607 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-3UTR | ENST00000276573 | ENST00000404674 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-intron | ENST00000276573 | ENST00000252329 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-3UTR | ENST00000350034 | ENST00000288607 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-3UTR | ENST00000350034 | ENST00000404674 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
intron-intron | ENST00000350034 | ENST00000252329 | TRIM55 | chr8 | 67084649 | + | PSMG3 | chr7 | 1607218 | - |
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FusionProtFeatures for TRIM55_PSMG3 |
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Hgene | Tgene |
TRIM55 | PSMG3 |
Chaperone protein which promotes assembly of the 20Sproteasome. May cooperate with PSMG1-PSMG2 heterodimers toorchestrate the correct assembly of proteasomes.{ECO:0000269|PubMed:17189198}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for TRIM55_PSMG3 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for TRIM55_PSMG3 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TRIM55_PSMG3 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TRIM55_PSMG3 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |