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Fusion gene ID: 39434 |
FusionGeneSummary for TRDMT1_NID2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TRDMT1_NID2 | Fusion gene ID: 39434 | Hgene | Tgene | Gene symbol | TRDMT1 | NID2 | Gene ID | 1787 | 22795 |
| Gene name | tRNA aspartic acid methyltransferase 1 | nidogen 2 | |
| Synonyms | DMNT2|DNMT2|MHSAIIP|PUMET|RNMT1 | NID-2 | |
| Cytomap | 10p13 | 14q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tRNA (cytosine(38)-C(5))-methyltransferaseDNA (cytosine-5)-methyltransferase-like protein 2DNA MTase homolog HsaIIPDNA cytosine-5 methyltransferase 2DNA methyltransferase-2tRNA (cytosine-5-)-methyltransferase | nidogen-2osteonidogen | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | O14717 | Q14112 | |
| Ensembl transtripts involved in fusion gene | ENST00000377799, ENST00000377766, ENST00000412821, ENST00000358282, ENST00000351358, ENST00000457442, ENST00000452380, ENST00000488990, | ENST00000541773, ENST00000216286, | |
| Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 4 X 4 X 2=32 |
| # samples | 6 | 4 | |
| ** MAII score | log2(6/4*10)=3.90689059560852 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TRDMT1 [Title/Abstract] AND NID2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TRDMT1 | GO:0030488 | tRNA methylation | 16424344 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA483206 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000377799 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| In-frame | ENST00000377799 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| 3UTR-3CDS | ENST00000377766 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| 3UTR-3CDS | ENST00000377766 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| In-frame | ENST00000412821 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| In-frame | ENST00000412821 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| 3UTR-3CDS | ENST00000358282 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| 3UTR-3CDS | ENST00000358282 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| In-frame | ENST00000351358 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| In-frame | ENST00000351358 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| In-frame | ENST00000457442 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| In-frame | ENST00000457442 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| 5UTR-3CDS | ENST00000452380 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| 5UTR-3CDS | ENST00000452380 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| intron-3CDS | ENST00000488990 | ENST00000541773 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
| intron-3CDS | ENST00000488990 | ENST00000216286 | TRDMT1 | chr10 | 17195506 | - | NID2 | chr14 | 52486897 | - |
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FusionProtFeatures for TRDMT1_NID2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TRDMT1 | NID2 |
| Specifically methylates cytosine 38 in the anticodonloop of tRNA(Asp). {ECO:0000269|PubMed:16424344}. | Cell adhesion glycoprotein which is widely distributedin basement membranes. Binds to collagens I and IV, to perlecanand to laminin 1. Does not bind fibulins. It probably has a rolein cell-extracellular matrix interactions. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000358282 | - | 8 | 9 | 4_391 | 308 | 143 | Domain | SAM-dependent MTase C5-type |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000351358 | - | 8 | 9 | 13_15 | 312 | 346 | Region | S-adenosyl-L-methionine binding |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000351358 | - | 8 | 9 | 57_58 | 312 | 346 | Region | S-adenosyl-L-methionine binding |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000358282 | - | 8 | 9 | 13_15 | 308 | 143 | Region | S-adenosyl-L-methionine binding |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000358282 | - | 8 | 9 | 57_58 | 308 | 143 | Region | S-adenosyl-L-methionine binding |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000377799 | - | 10 | 11 | 13_15 | 358 | 392 | Region | S-adenosyl-L-methionine binding |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000377799 | - | 10 | 11 | 57_58 | 358 | 392 | Region | S-adenosyl-L-methionine binding |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000412821 | - | 9 | 10 | 13_15 | 334 | 368 | Region | S-adenosyl-L-methionine binding |
| Hgene | TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000412821 | - | 9 | 10 | 57_58 | 334 | 368 | Region | S-adenosyl-L-methionine binding |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 1016_1084 | 891 | 1376 | Domain | Thyroglobulin type-1 2 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 892_930 | 891 | 1376 | Domain | EGF-like 5%3B calcium-binding |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 937_1005 | 891 | 1376 | Domain | Thyroglobulin type-1 1 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 1016_1084 | 790 | 1275 | Domain | Thyroglobulin type-1 2 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 801_843 | 790 | 1275 | Domain | EGF-like 3%3B calcium-binding |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 848_891 | 790 | 1275 | Domain | EGF-like 4 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 892_930 | 790 | 1275 | Domain | EGF-like 5%3B calcium-binding |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 937_1005 | 790 | 1275 | Domain | Thyroglobulin type-1 1 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 1154_1197 | 891 | 1376 | Repeat | Note=LDL-receptor class B 1 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 1198_1240 | 891 | 1376 | Repeat | Note=LDL-receptor class B 2 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 1241_1285 | 891 | 1376 | Repeat | Note=LDL-receptor class B 3 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 1286_1327 | 891 | 1376 | Repeat | Note=LDL-receptor class B 4 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 1329_1373 | 891 | 1376 | Repeat | Note=LDL-receptor class B 5 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 1154_1197 | 790 | 1275 | Repeat | Note=LDL-receptor class B 1 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 1198_1240 | 790 | 1275 | Repeat | Note=LDL-receptor class B 2 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 1241_1285 | 790 | 1275 | Repeat | Note=LDL-receptor class B 3 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 1286_1327 | 790 | 1275 | Repeat | Note=LDL-receptor class B 4 |
| Tgene | >NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 1329_1373 | 790 | 1275 | Repeat | Note=LDL-receptor class B 5 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000351358 | - | 8 | 9 | 4_391 | 312 | 346 | Domain | SAM-dependent MTase C5-type |
| Hgene | >TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000377799 | - | 10 | 11 | 4_391 | 358 | 392 | Domain | SAM-dependent MTase C5-type |
| Hgene | >TRDMT1 | chr10:17195506 | chr14:52486897 | ENST00000412821 | - | 9 | 10 | 4_391 | 334 | 368 | Domain | SAM-dependent MTase C5-type |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 108_273 | 891 | 1376 | Domain | NIDO |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 484_524 | 891 | 1376 | Domain | EGF-like 1 |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 528_758 | 891 | 1376 | Domain | Nidogen G2 beta-barrel |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 759_800 | 891 | 1376 | Domain | EGF-like 2 |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 801_843 | 891 | 1376 | Domain | EGF-like 3%3B calcium-binding |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000216286 | - | 11 | 22 | 848_891 | 891 | 1376 | Domain | EGF-like 4 |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 108_273 | 790 | 1275 | Domain | NIDO |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 484_524 | 790 | 1275 | Domain | EGF-like 1 |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 528_758 | 790 | 1275 | Domain | Nidogen G2 beta-barrel |
| Tgene | NID2 | chr10:17195506 | chr14:52486897 | ENST00000541773 | - | 11 | 22 | 759_800 | 790 | 1275 | Domain | EGF-like 2 |
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FusionGeneSequence for TRDMT1_NID2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TRDMT1_ENST00000377799_chr10_17195506_-_NID2_ENST00000541773_chr14_52486897_-_3260nt ACGGACCGGCAGGCCTAGCTCCGGGGCTGCGGCGGCTGAGGCGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGC GGCATGCACCACGCGCTGAGAGAAAGCTGTATACCTGCACAAGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAG TATAATTTTCCTCACACACAGTTACTTGCCAAGACGATTGAAGGCATTACACTCGAAGAGTTTGACAGATTATCTTTTGATATGATTTTA ATGAGCCCTCCCTGCCAGCCATTCACAAGGATTGGCCGGCAGGGTGATATGACTGATTCAAGGACGAATAGCTTCTTACATATTCTAGAT ATTCTCCCAAGATTACAAAAATTACCAAAGTATATTCTTTTGGAAAATGTTAAAGGTTTTGAAGTATCTTCTACAAGAGACCTCTTGATA CAAACAATAGAAAATTGTGGCTTTCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCATTCCAAATTCAAGGCTACGATATTTT CTTATTGCAAAGCTTCAGTCAGAGCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGTTCCCCAAAATTGAATCTGTACATCCA CAAAAATATGCAATGGATGTAGAAAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCTTTGATGGCAGCATACAGTGTTCTGGA AAAGATGCCATTCTTTTTAAGCTTGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATAGTGATCTCTCTGTGAAAATGCTAAAA GATTTTCTTGAAGATGACACTGACGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGATATGCTCTTCTGTTAGACATTGTTCAG CCCACTTGTAGAAGGTCCGTGTGCTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGTCTGTGTTACAGACTGCAGAGGATGTG CAGGTTGAGAATATCTACAAATCCCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGTTAATACTTAAACTGCGATATTTCACT CCTAAAGAAATAGCAAATCTCCTTGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAAACAGATGTCACCCTGCAGCTACCTGC TACAATACTCCTGGTTCCTTCTCCTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGTGCATACCTGACTCCACCTCAAGCCTG ACACCCTGTGAACAACAGCAGCGCCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCCACATCCCCCAATGCGACGAGCAGGGC AACTTCCTGCCCCTACAGTGTCATGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTCATGAAGTTCCTGGTACCCAGACTCCA CCTGGCTCCACCCCGCCTCACTGTGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCTGTGAGCGCTGGAGGGAAAACCTGCTG GAGCACTACGGTGGCACCCCCCGGGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACTTCATCCCCCTGCAGTGCCACGGAAAG AGCGACTTCTGCTGGTGTGTGGACAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAGGCACCACCCCTGCGTGTATACCCACC GTCGCTCCACCCATGGTCCGGCCCACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCTTCCTGCTCTATACTCAGGGCCAGCAG ATTGGCTACTTACCCCTCAATGGCACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTCTGCATGGCTCCATAATCGTGGGAATT GATTACGACTGCCGGGAGAGGATGGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTGCTGGTCTGGAACTGGGAGCAGAGCCT GAGACGATCGTGAATTCAGGTCTGATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAACAATGTACTGGACGGACAGTGTCCTG GATAAGATAGAGAGCGCCCTGCTGGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGGTGAATCCCCGTGCCATCGCTGTGGAT CCAATCCGAGGCAACTTGTACTGGACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCATCTTTAGATGGAGAAAACAGAAGAATT CTGATCAATACAGACATTGGATTGCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCTGCTGGGCAGATGCAGGAACCAAAAAA CTGGAGTGTACACTACCTGATGGAACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCTTCAGCATCGTAAGCTATGCAGATCAC TTCTACCACACAGACTGGAGGAGGGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTACTGATGAGTATCTCCCAGAACAACGA TCTCACCTCTACGGGATAACTGCAGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGTAATGTAAAGGAAGACTTGGAGTTTAC AATCAGAACCTGGACCCTAAAGAACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGCCATTAGACGTTCCTGAGCATCCAAGA TGAACATTTTGTAGTGCAAAAAGACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTATTTTTAAAAATGAAGGTTGTTATTGCA AGTTTAAAAAGGTAACAGAATTTTAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATCATTAATATTTAAAAGATCAAATTCAT TCAACTAAGAATTAGAGTTTAAGACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAGAAATTAAAGCACATGTGATCAATATA ACAATATAATCCTAAACCTTGACAGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAATTATTTATAGTTTCCCAACAAAAGTTC TAAGATTTTTTACCTCTGCATCAGTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAATTTGCATTTTCTGATCCTGTAGTGCC TCTATAGAAGTACCCACAGAAAGTAAAGTATCACATTTATAAATACCAAAGATGTAACAATTTTAAAATTTTCTAGATTACTCCAATAAA >In-frame_TRDMT1_ENST00000377799_chr10_17195506_-_NID2_ENST00000216286_chr14_52486897_-_3260nt ACGGACCGGCAGGCCTAGCTCCGGGGCTGCGGCGGCTGAGGCGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGC GGCATGCACCACGCGCTGAGAGAAAGCTGTATACCTGCACAAGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAG TATAATTTTCCTCACACACAGTTACTTGCCAAGACGATTGAAGGCATTACACTCGAAGAGTTTGACAGATTATCTTTTGATATGATTTTA ATGAGCCCTCCCTGCCAGCCATTCACAAGGATTGGCCGGCAGGGTGATATGACTGATTCAAGGACGAATAGCTTCTTACATATTCTAGAT ATTCTCCCAAGATTACAAAAATTACCAAAGTATATTCTTTTGGAAAATGTTAAAGGTTTTGAAGTATCTTCTACAAGAGACCTCTTGATA CAAACAATAGAAAATTGTGGCTTTCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCATTCCAAATTCAAGGCTACGATATTTT CTTATTGCAAAGCTTCAGTCAGAGCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGTTCCCCAAAATTGAATCTGTACATCCA CAAAAATATGCAATGGATGTAGAAAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCTTTGATGGCAGCATACAGTGTTCTGGA AAAGATGCCATTCTTTTTAAGCTTGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATAGTGATCTCTCTGTGAAAATGCTAAAA GATTTTCTTGAAGATGACACTGACGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGATATGCTCTTCTGTTAGACATTGTTCAG CCCACTTGTAGAAGGTCCGTGTGCTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGTCTGTGTTACAGACTGCAGAGGATGTG CAGGTTGAGAATATCTACAAATCCCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGTTAATACTTAAACTGCGATATTTCACT CCTAAAGAAATAGCAAATCTCCTTGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAAACAGATGTCACCCTGCAGCTACCTGC TACAATACTCCTGGTTCCTTCTCCTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGTGCATACCTGACTCCACCTCAAGCCTG ACACCCTGTGAACAACAGCAGCGCCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCCACATCCCCCAATGCGACGAGCAGGGC AACTTCCTGCCCCTACAGTGTCATGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTCATGAAGTTCCTGGTACCCAGACTCCA CCTGGCTCCACCCCGCCTCACTGTGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCTGTGAGCGCTGGAGGGAAAACCTGCTG GAGCACTACGGTGGCACCCCCCGGGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACTTCATCCCCCTGCAGTGCCACGGAAAG AGCGACTTCTGCTGGTGTGTGGACAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAGGCACCACCCCTGCGTGTATACCCACC GTCGCTCCACCCATGGTCCGGCCCACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCTTCCTGCTCTATACTCAGGGCCAGCAG ATTGGCTACTTACCCCTCAATGGCACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTCTGCATGGCTCCATAATCGTGGGAATT GATTACGACTGCCGGGAGAGGATGGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTGCTGGTCTGGAACTGGGAGCAGAGCCT GAGACGATCGTGAATTCAGGTCTGATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAACAATGTACTGGACGGACAGTGTCCTG GATAAGATAGAGAGCGCCCTGCTGGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGGTGAATCCCCGTGCCATCGCTGTGGAT CCAATCCGAGGCAACTTGTACTGGACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCATCTTTAGATGGAGAAAACAGAAGAATT CTGATCAATACAGACATTGGATTGCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCTGCTGGGCAGATGCAGGAACCAAAAAA CTGGAGTGTACACTACCTGATGGAACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCTTCAGCATCGTAAGCTATGCAGATCAC TTCTACCACACAGACTGGAGGAGGGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTACTGATGAGTATCTCCCAGAACAACGA TCTCACCTCTACGGGATAACTGCAGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGTAATGTAAAGGAAGACTTGGAGTTTAC AATCAGAACCTGGACCCTAAAGAACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGCCATTAGACGTTCCTGAGCATCCAAGA TGAACATTTTGTAGTGCAAAAAGACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTATTTTTAAAAATGAAGGTTGTTATTGCA AGTTTAAAAAGGTAACAGAATTTTAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATCATTAATATTTAAAAGATCAAATTCAT TCAACTAAGAATTAGAGTTTAAGACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAGAAATTAAAGCACATGTGATCAATATA ACAATATAATCCTAAACCTTGACAGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAATTATTTATAGTTTCCCAACAAAAGTTC TAAGATTTTTTACCTCTGCATCAGTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAATTTGCATTTTCTGATCCTGTAGTGCC TCTATAGAAGTACCCACAGAAAGTAAAGTATCACATTTATAAATACCAAAGATGTAACAATTTTAAAATTTTCTAGATTACTCCAATAAA >In-frame_TRDMT1_ENST00000412821_chr10_17195506_-_NID2_ENST00000541773_chr14_52486897_-_3147nt CGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGCGGCATGCACCACGCGCTGAGAGAAAGCTGTATACCTGCACA AGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAGTATAATTTTCCTCACACACAGTTACTTGCCAAGACGATTGA AGGCATTACACTCGAAGAGTTTGACAGATTATCTTTTGATATGATTTTAATGAGCCCTCCCTGCCAGCCATTCACAAGATTACAAAAATT ACCAAAGTATATTCTTTTGGAAAATGTTAAAGGTTTTGAAGTATCTTCTACAAGAGACCTCTTGATACAAACAATAGAAAATTGTGGCTT TCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCATTCCAAATTCAAGGCTACGATATTTTCTTATTGCAAAGCTTCAGTCAGA GCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGTTCCCCAAAATTGAATCTGTACATCCACAAAAATATGCAATGGATGTAGA AAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCTTTGATGGCAGCATACAGTGTTCTGGAAAAGATGCCATTCTTTTTAAGCT TGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATAGTGATCTCTCTGTGAAAATGCTAAAAGATTTTCTTGAAGATGACACTGA CGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGATATGCTCTTCTGTTAGACATTGTTCAGCCCACTTGTAGAAGGTCCGTGTG CTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGTCTGTGTTACAGACTGCAGAGGATGTGCAGGTTGAGAATATCTACAAATC CCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGTTAATACTTAAACTGCGATATTTCACTCCTAAAGAAATAGCAAATCTCCT TGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAAACAGATGTCACCCTGCAGCTACCTGCTACAATACTCCTGGTTCCTTCTC CTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGTGCATACCTGACTCCACCTCAAGCCTGACACCCTGTGAACAACAGCAGCG CCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCCACATCCCCCAATGCGACGAGCAGGGCAACTTCCTGCCCCTACAGTGTCA TGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTCATGAAGTTCCTGGTACCCAGACTCCACCTGGCTCCACCCCGCCTCACTG TGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCTGTGAGCGCTGGAGGGAAAACCTGCTGGAGCACTACGGTGGCACCCCCCG GGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACTTCATCCCCCTGCAGTGCCACGGAAAGAGCGACTTCTGCTGGTGTGTGGA CAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAGGCACCACCCCTGCGTGTATACCCACCGTCGCTCCACCCATGGTCCGGCC CACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCTTCCTGCTCTATACTCAGGGCCAGCAGATTGGCTACTTACCCCTCAATGG CACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTCTGCATGGCTCCATAATCGTGGGAATTGATTACGACTGCCGGGAGAGGAT GGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTGCTGGTCTGGAACTGGGAGCAGAGCCTGAGACGATCGTGAATTCAGGTCT GATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAACAATGTACTGGACGGACAGTGTCCTGGATAAGATAGAGAGCGCCCTGCT GGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGGTGAATCCCCGTGCCATCGCTGTGGATCCAATCCGAGGCAACTTGTACTG GACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCATCTTTAGATGGAGAAAACAGAAGAATTCTGATCAATACAGACATTGGATT GCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCTGCTGGGCAGATGCAGGAACCAAAAAACTGGAGTGTACACTACCTGATGG AACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCTTCAGCATCGTAAGCTATGCAGATCACTTCTACCACACAGACTGGAGGAG GGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTACTGATGAGTATCTCCCAGAACAACGATCTCACCTCTACGGGATAACTGC AGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGTAATGTAAAGGAAGACTTGGAGTTTACAATCAGAACCTGGACCCTAAAGA ACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGCCATTAGACGTTCCTGAGCATCCAAGATGAACATTTTGTAGTGCAAAAAG ACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTATTTTTAAAAATGAAGGTTGTTATTGCAAGTTTAAAAAGGTAACAGAATTT TAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATCATTAATATTTAAAAGATCAAATTCATTCAACTAAGAATTAGAGTTTAAG ACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAGAAATTAAAGCACATGTGATCAATATAACAATATAATCCTAAACCTTGAC AGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAATTATTTATAGTTTCCCAACAAAAGTTCTAAGATTTTTTACCTCTGCATCA GTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAATTTGCATTTTCTGATCCTGTAGTGCCTCTATAGAAGTACCCACAGAAAG >In-frame_TRDMT1_ENST00000412821_chr10_17195506_-_NID2_ENST00000216286_chr14_52486897_-_3147nt CGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGCGGCATGCACCACGCGCTGAGAGAAAGCTGTATACCTGCACA AGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAGTATAATTTTCCTCACACACAGTTACTTGCCAAGACGATTGA AGGCATTACACTCGAAGAGTTTGACAGATTATCTTTTGATATGATTTTAATGAGCCCTCCCTGCCAGCCATTCACAAGATTACAAAAATT ACCAAAGTATATTCTTTTGGAAAATGTTAAAGGTTTTGAAGTATCTTCTACAAGAGACCTCTTGATACAAACAATAGAAAATTGTGGCTT TCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCATTCCAAATTCAAGGCTACGATATTTTCTTATTGCAAAGCTTCAGTCAGA GCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGTTCCCCAAAATTGAATCTGTACATCCACAAAAATATGCAATGGATGTAGA AAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCTTTGATGGCAGCATACAGTGTTCTGGAAAAGATGCCATTCTTTTTAAGCT TGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATAGTGATCTCTCTGTGAAAATGCTAAAAGATTTTCTTGAAGATGACACTGA CGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGATATGCTCTTCTGTTAGACATTGTTCAGCCCACTTGTAGAAGGTCCGTGTG CTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGTCTGTGTTACAGACTGCAGAGGATGTGCAGGTTGAGAATATCTACAAATC CCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGTTAATACTTAAACTGCGATATTTCACTCCTAAAGAAATAGCAAATCTCCT TGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAAACAGATGTCACCCTGCAGCTACCTGCTACAATACTCCTGGTTCCTTCTC CTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGTGCATACCTGACTCCACCTCAAGCCTGACACCCTGTGAACAACAGCAGCG CCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCCACATCCCCCAATGCGACGAGCAGGGCAACTTCCTGCCCCTACAGTGTCA TGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTCATGAAGTTCCTGGTACCCAGACTCCACCTGGCTCCACCCCGCCTCACTG TGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCTGTGAGCGCTGGAGGGAAAACCTGCTGGAGCACTACGGTGGCACCCCCCG GGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACTTCATCCCCCTGCAGTGCCACGGAAAGAGCGACTTCTGCTGGTGTGTGGA CAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAGGCACCACCCCTGCGTGTATACCCACCGTCGCTCCACCCATGGTCCGGCC CACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCTTCCTGCTCTATACTCAGGGCCAGCAGATTGGCTACTTACCCCTCAATGG CACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTCTGCATGGCTCCATAATCGTGGGAATTGATTACGACTGCCGGGAGAGGAT GGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTGCTGGTCTGGAACTGGGAGCAGAGCCTGAGACGATCGTGAATTCAGGTCT GATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAACAATGTACTGGACGGACAGTGTCCTGGATAAGATAGAGAGCGCCCTGCT GGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGGTGAATCCCCGTGCCATCGCTGTGGATCCAATCCGAGGCAACTTGTACTG GACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCATCTTTAGATGGAGAAAACAGAAGAATTCTGATCAATACAGACATTGGATT GCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCTGCTGGGCAGATGCAGGAACCAAAAAACTGGAGTGTACACTACCTGATGG AACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCTTCAGCATCGTAAGCTATGCAGATCACTTCTACCACACAGACTGGAGGAG GGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTACTGATGAGTATCTCCCAGAACAACGATCTCACCTCTACGGGATAACTGC AGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGTAATGTAAAGGAAGACTTGGAGTTTACAATCAGAACCTGGACCCTAAAGA ACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGCCATTAGACGTTCCTGAGCATCCAAGATGAACATTTTGTAGTGCAAAAAG ACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTATTTTTAAAAATGAAGGTTGTTATTGCAAGTTTAAAAAGGTAACAGAATTT TAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATCATTAATATTTAAAAGATCAAATTCATTCAACTAAGAATTAGAGTTTAAG ACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAGAAATTAAAGCACATGTGATCAATATAACAATATAATCCTAAACCTTGAC AGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAATTATTTATAGTTTCCCAACAAAAGTTCTAAGATTTTTTACCTCTGCATCA GTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAATTTGCATTTTCTGATCCTGTAGTGCCTCTATAGAAGTACCCACAGAAAG >In-frame_TRDMT1_ENST00000351358_chr10_17195506_-_NID2_ENST00000541773_chr14_52486897_-_3081nt CGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGCGGCATGCACCACGCGCTGAGAGAAAGCTGTATACCTGCACA AGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAGTATAATTTTCCTCACACACAGTTACTTGCCAAGACGATTGA AGGCATTACACTCGAAGAGTTTGACAGATTATCTTTTGATATGATTTTAATGAGCCCTCCCTGCCAGCCATTCACAAGAGACCTCTTGAT ACAAACAATAGAAAATTGTGGCTTTCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCATTCCAAATTCAAGGCTACGATATTT TCTTATTGCAAAGCTTCAGTCAGAGCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGTTCCCCAAAATTGAATCTGTACATCC ACAAAAATATGCAATGGATGTAGAAAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCTTTGATGGCAGCATACAGTGTTCTGG AAAAGATGCCATTCTTTTTAAGCTTGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATAGTGATCTCTCTGTGAAAATGCTAAA AGATTTTCTTGAAGATGACACTGACGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGATATGCTCTTCTGTTAGACATTGTTCA GCCCACTTGTAGAAGGTCCGTGTGCTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGTCTGTGTTACAGACTGCAGAGGATGT GCAGGTTGAGAATATCTACAAATCCCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGTTAATACTTAAACTGCGATATTTCAC TCCTAAAGAAATAGCAAATCTCCTTGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAAACAGATGTCACCCTGCAGCTACCTG CTACAATACTCCTGGTTCCTTCTCCTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGTGCATACCTGACTCCACCTCAAGCCT GACACCCTGTGAACAACAGCAGCGCCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCCACATCCCCCAATGCGACGAGCAGGG CAACTTCCTGCCCCTACAGTGTCATGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTCATGAAGTTCCTGGTACCCAGACTCC ACCTGGCTCCACCCCGCCTCACTGTGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCTGTGAGCGCTGGAGGGAAAACCTGCT GGAGCACTACGGTGGCACCCCCCGGGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACTTCATCCCCCTGCAGTGCCACGGAAA GAGCGACTTCTGCTGGTGTGTGGACAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAGGCACCACCCCTGCGTGTATACCCAC CGTCGCTCCACCCATGGTCCGGCCCACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCTTCCTGCTCTATACTCAGGGCCAGCA GATTGGCTACTTACCCCTCAATGGCACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTCTGCATGGCTCCATAATCGTGGGAAT TGATTACGACTGCCGGGAGAGGATGGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTGCTGGTCTGGAACTGGGAGCAGAGCC TGAGACGATCGTGAATTCAGGTCTGATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAACAATGTACTGGACGGACAGTGTCCT GGATAAGATAGAGAGCGCCCTGCTGGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGGTGAATCCCCGTGCCATCGCTGTGGA TCCAATCCGAGGCAACTTGTACTGGACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCATCTTTAGATGGAGAAAACAGAAGAAT TCTGATCAATACAGACATTGGATTGCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCTGCTGGGCAGATGCAGGAACCAAAAA ACTGGAGTGTACACTACCTGATGGAACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCTTCAGCATCGTAAGCTATGCAGATCA CTTCTACCACACAGACTGGAGGAGGGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTACTGATGAGTATCTCCCAGAACAACG ATCTCACCTCTACGGGATAACTGCAGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGTAATGTAAAGGAAGACTTGGAGTTTA CAATCAGAACCTGGACCCTAAAGAACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGCCATTAGACGTTCCTGAGCATCCAAG ATGAACATTTTGTAGTGCAAAAAGACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTATTTTTAAAAATGAAGGTTGTTATTGC AAGTTTAAAAAGGTAACAGAATTTTAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATCATTAATATTTAAAAGATCAAATTCA TTCAACTAAGAATTAGAGTTTAAGACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAGAAATTAAAGCACATGTGATCAATAT AACAATATAATCCTAAACCTTGACAGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAATTATTTATAGTTTCCCAACAAAAGTT CTAAGATTTTTTACCTCTGCATCAGTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAATTTGCATTTTCTGATCCTGTAGTGC CTCTATAGAAGTACCCACAGAAAGTAAAGTATCACATTTATAAATACCAAAGATGTAACAATTTTAAAATTTTCTAGATTACTCCAATAA >In-frame_TRDMT1_ENST00000351358_chr10_17195506_-_NID2_ENST00000216286_chr14_52486897_-_3081nt CGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGCGGCATGCACCACGCGCTGAGAGAAAGCTGTATACCTGCACA AGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAGTATAATTTTCCTCACACACAGTTACTTGCCAAGACGATTGA AGGCATTACACTCGAAGAGTTTGACAGATTATCTTTTGATATGATTTTAATGAGCCCTCCCTGCCAGCCATTCACAAGAGACCTCTTGAT ACAAACAATAGAAAATTGTGGCTTTCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCATTCCAAATTCAAGGCTACGATATTT TCTTATTGCAAAGCTTCAGTCAGAGCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGTTCCCCAAAATTGAATCTGTACATCC ACAAAAATATGCAATGGATGTAGAAAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCTTTGATGGCAGCATACAGTGTTCTGG AAAAGATGCCATTCTTTTTAAGCTTGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATAGTGATCTCTCTGTGAAAATGCTAAA AGATTTTCTTGAAGATGACACTGACGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGATATGCTCTTCTGTTAGACATTGTTCA GCCCACTTGTAGAAGGTCCGTGTGCTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGTCTGTGTTACAGACTGCAGAGGATGT GCAGGTTGAGAATATCTACAAATCCCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGTTAATACTTAAACTGCGATATTTCAC TCCTAAAGAAATAGCAAATCTCCTTGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAAACAGATGTCACCCTGCAGCTACCTG CTACAATACTCCTGGTTCCTTCTCCTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGTGCATACCTGACTCCACCTCAAGCCT GACACCCTGTGAACAACAGCAGCGCCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCCACATCCCCCAATGCGACGAGCAGGG CAACTTCCTGCCCCTACAGTGTCATGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTCATGAAGTTCCTGGTACCCAGACTCC ACCTGGCTCCACCCCGCCTCACTGTGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCTGTGAGCGCTGGAGGGAAAACCTGCT GGAGCACTACGGTGGCACCCCCCGGGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACTTCATCCCCCTGCAGTGCCACGGAAA GAGCGACTTCTGCTGGTGTGTGGACAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAGGCACCACCCCTGCGTGTATACCCAC CGTCGCTCCACCCATGGTCCGGCCCACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCTTCCTGCTCTATACTCAGGGCCAGCA GATTGGCTACTTACCCCTCAATGGCACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTCTGCATGGCTCCATAATCGTGGGAAT TGATTACGACTGCCGGGAGAGGATGGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTGCTGGTCTGGAACTGGGAGCAGAGCC TGAGACGATCGTGAATTCAGGTCTGATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAACAATGTACTGGACGGACAGTGTCCT GGATAAGATAGAGAGCGCCCTGCTGGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGGTGAATCCCCGTGCCATCGCTGTGGA TCCAATCCGAGGCAACTTGTACTGGACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCATCTTTAGATGGAGAAAACAGAAGAAT TCTGATCAATACAGACATTGGATTGCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCTGCTGGGCAGATGCAGGAACCAAAAA ACTGGAGTGTACACTACCTGATGGAACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCTTCAGCATCGTAAGCTATGCAGATCA CTTCTACCACACAGACTGGAGGAGGGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTACTGATGAGTATCTCCCAGAACAACG ATCTCACCTCTACGGGATAACTGCAGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGTAATGTAAAGGAAGACTTGGAGTTTA CAATCAGAACCTGGACCCTAAAGAACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGCCATTAGACGTTCCTGAGCATCCAAG ATGAACATTTTGTAGTGCAAAAAGACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTATTTTTAAAAATGAAGGTTGTTATTGC AAGTTTAAAAAGGTAACAGAATTTTAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATCATTAATATTTAAAAGATCAAATTCA TTCAACTAAGAATTAGAGTTTAAGACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAGAAATTAAAGCACATGTGATCAATAT AACAATATAATCCTAAACCTTGACAGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAATTATTTATAGTTTCCCAACAAAAGTT CTAAGATTTTTTACCTCTGCATCAGTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAATTTGCATTTTCTGATCCTGTAGTGC CTCTATAGAAGTACCCACAGAAAGTAAAGTATCACATTTATAAATACCAAAGATGTAACAATTTTAAAATTTTCTAGATTACTCCAATAA >In-frame_TRDMT1_ENST00000457442_chr10_17195506_-_NID2_ENST00000541773_chr14_52486897_-_3286nt ATTCGGGAAGCCTTATTGTTTTCCGTCCTTTGTTCCCCTCTAGACCCTTGCCAATCCCCAGGCCGCGAGGCCCTCTGAAGCCCTGAGCCT GGAGCGGTAGGAGACGGGGGAACTGAAACGCCGCGGAACCAGAGGCTGAGGGAGCGGCGCGATGGAGGGAGGAGGAGCGACGGACCGGCA GGCCTAGCTCCGGGGCTGCGGCGGCTGAGGCGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGCGGCATGCACCA CGCGCTGAGAGAAAGCTGTATACCTGCACAAGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAGTATAATTTTCC TCACACACAGTTACTTGCCAAGACGATTGAAGATTGGCCGGCAGGGTGATATGACTGATTCAAGGACGAATAGCTTCTTACATATTCTAG ATATTCTCCCAAGAGACCTCTTGATACAAACAATAGAAAATTGTGGCTTTCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCA TTCCAAATTCAAGGCTACGATATTTTCTTATTGCAAAGCTTCAGTCAGAGCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGT TCCCCAAAATTGAATCTGTACATCCACAAAAATATGCAATGGATGTAGAAAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCT TTGATGGCAGCATACAGTGTTCTGGAAAAGATGCCATTCTTTTTAAGCTTGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATA GTGATCTCTCTGTGAAAATGCTAAAAGATTTTCTTGAAGATGACACTGACGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGAT ATGCTCTTCTGTTAGACATTGTTCAGCCCACTTGTAGAAGGTCCGTGTGCTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGT CTGTGTTACAGACTGCAGAGGATGTGCAGGTTGAGAATATCTACAAATCCCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGT TAATACTTAAACTGCGATATTTCACTCCTAAAGAAATAGCAAATCTCCTTGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAA ACAGATGTCACCCTGCAGCTACCTGCTACAATACTCCTGGTTCCTTCTCCTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGT GCATACCTGACTCCACCTCAAGCCTGACACCCTGTGAACAACAGCAGCGCCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCC ACATCCCCCAATGCGACGAGCAGGGCAACTTCCTGCCCCTACAGTGTCATGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTC ATGAAGTTCCTGGTACCCAGACTCCACCTGGCTCCACCCCGCCTCACTGTGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCT GTGAGCGCTGGAGGGAAAACCTGCTGGAGCACTACGGTGGCACCCCCCGGGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACT TCATCCCCCTGCAGTGCCACGGAAAGAGCGACTTCTGCTGGTGTGTGGACAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAG GCACCACCCCTGCGTGTATACCCACCGTCGCTCCACCCATGGTCCGGCCCACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCT TCCTGCTCTATACTCAGGGCCAGCAGATTGGCTACTTACCCCTCAATGGCACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTC TGCATGGCTCCATAATCGTGGGAATTGATTACGACTGCCGGGAGAGGATGGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTG CTGGTCTGGAACTGGGAGCAGAGCCTGAGACGATCGTGAATTCAGGTCTGATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAA CAATGTACTGGACGGACAGTGTCCTGGATAAGATAGAGAGCGCCCTGCTGGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGG TGAATCCCCGTGCCATCGCTGTGGATCCAATCCGAGGCAACTTGTACTGGACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCAT CTTTAGATGGAGAAAACAGAAGAATTCTGATCAATACAGACATTGGATTGCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCT GCTGGGCAGATGCAGGAACCAAAAAACTGGAGTGTACACTACCTGATGGAACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCT TCAGCATCGTAAGCTATGCAGATCACTTCTACCACACAGACTGGAGGAGGGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTA CTGATGAGTATCTCCCAGAACAACGATCTCACCTCTACGGGATAACTGCAGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGT AATGTAAAGGAAGACTTGGAGTTTACAATCAGAACCTGGACCCTAAAGAACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGC CATTAGACGTTCCTGAGCATCCAAGATGAACATTTTGTAGTGCAAAAAGACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTAT TTTTAAAAATGAAGGTTGTTATTGCAAGTTTAAAAAGGTAACAGAATTTTAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATC ATTAATATTTAAAAGATCAAATTCATTCAACTAAGAATTAGAGTTTAAGACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAG AAATTAAAGCACATGTGATCAATATAACAATATAATCCTAAACCTTGACAGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAAT TATTTATAGTTTCCCAACAAAAGTTCTAAGATTTTTTACCTCTGCATCAGTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAA TTTGCATTTTCTGATCCTGTAGTGCCTCTATAGAAGTACCCACAGAAAGTAAAGTATCACATTTATAAATACCAAAGATGTAACAATTTT >In-frame_TRDMT1_ENST00000457442_chr10_17195506_-_NID2_ENST00000216286_chr14_52486897_-_3286nt ATTCGGGAAGCCTTATTGTTTTCCGTCCTTTGTTCCCCTCTAGACCCTTGCCAATCCCCAGGCCGCGAGGCCCTCTGAAGCCCTGAGCCT GGAGCGGTAGGAGACGGGGGAACTGAAACGCCGCGGAACCAGAGGCTGAGGGAGCGGCGCGATGGAGGGAGGAGGAGCGACGGACCGGCA GGCCTAGCTCCGGGGCTGCGGCGGCTGAGGCGCGGGGATGGAGCCCCTGCGGGTGCTGGAGCTATACAGCGGCGTGGGCGGCATGCACCA CGCGCTGAGAGAAAGCTGTATACCTGCACAAGTGGTGGCTGCCATTGATGTCAACACTGTCGCTAATGAAGTATACAAGTATAATTTTCC TCACACACAGTTACTTGCCAAGACGATTGAAGATTGGCCGGCAGGGTGATATGACTGATTCAAGGACGAATAGCTTCTTACATATTCTAG ATATTCTCCCAAGAGACCTCTTGATACAAACAATAGAAAATTGTGGCTTTCAGTACCAAGAGTTTCTATTATCTCCAACCTCTCTTGGCA TTCCAAATTCAAGGCTACGATATTTTCTTATTGCAAAGCTTCAGTCAGAGCCATTACCCTTTCAAGCCCCTGGTCAGGTACTGATGGAGT TCCCCAAAATTGAATCTGTACATCCACAAAAATATGCAATGGATGTAGAAAATAAAATTCAAGAAAAGAACGTTGAACCAAATATTAGCT TTGATGGCAGCATACAGTGTTCTGGAAAAGATGCCATTCTTTTTAAGCTTGAAACTGCAGAAGAAATTCACAGGAAAAATCAACAAGATA GTGATCTCTCTGTGAAAATGCTAAAAGATTTTCTTGAAGATGACACTGACGTGAACCAGTATCTTTTACCACCAAAGTCATTGCTGCGAT ATGCTCTTCTGTTAGACATTGTTCAGCCCACTTGTAGAAGGTCCGTGTGCTTTACCAAAGGATATGGAAGCTACATAGAAGGGACAGGGT CTGTGTTACAGACTGCAGAGGATGTGCAGGTTGAGAATATCTACAAATCCCTTACCAATTTGTCACAAGAAGAACAGATAACAAAGCTGT TAATACTTAAACTGCGATATTTCACTCCTAAAGAAATAGCAAATCTCCTTGGATTTCCTCCAGAGTTCGATGTAGATGAATGCTCAGAAA ACAGATGTCACCCTGCAGCTACCTGCTACAATACTCCTGGTTCCTTCTCCTGCCGTTGTCAACCCGGATATTATGGGGATGGATTTCAGT GCATACCTGACTCCACCTCAAGCCTGACACCCTGTGAACAACAGCAGCGCCATGCCCAGGCCCAGTATGCCTACCCTGGGGCCCGGTTCC ACATCCCCCAATGCGACGAGCAGGGCAACTTCCTGCCCCTACAGTGTCATGGCAGCACTGGTTTCTGCTGGTGCGTGGACCCTGATGGTC ATGAAGTTCCTGGTACCCAGACTCCACCTGGCTCCACCCCGCCTCACTGTGGACCATCACCAGAGCCCACCCAGAGGCCCCCGACCATCT GTGAGCGCTGGAGGGAAAACCTGCTGGAGCACTACGGTGGCACCCCCCGGGATGACCAGTACGTGCCCCAGTGCGATGACCTGGGCCACT TCATCCCCCTGCAGTGCCACGGAAAGAGCGACTTCTGCTGGTGTGTGGACAAAGATGGCAGAGAGGTGCAGGGCACCCGCTCCCAGCCAG GCACCACCCCTGCGTGTATACCCACCGTCGCTCCACCCATGGTCCGGCCCACGCCCCGGCCAGATGTGACCCCTCCATCTGTGGGCACCT TCCTGCTCTATACTCAGGGCCAGCAGATTGGCTACTTACCCCTCAATGGCACCAGGCTTCAGAAGGATGCAGCTAAGACCCTGCTGTCTC TGCATGGCTCCATAATCGTGGGAATTGATTACGACTGCCGGGAGAGGATGGTGTACTGGACAGATGTTGCTGGACGGACAATCAGCCGTG CTGGTCTGGAACTGGGAGCAGAGCCTGAGACGATCGTGAATTCAGGTCTGATAAGCCCTGAAGGACTTGCCATAGACCACATCCGCAGAA CAATGTACTGGACGGACAGTGTCCTGGATAAGATAGAGAGCGCCCTGCTGGATGGCTCTGAGCGCAAGGTCCTCTTCTACACAGATCTGG TGAATCCCCGTGCCATCGCTGTGGATCCAATCCGAGGCAACTTGTACTGGACAGACTGGAATAGAGAAGCTCCTAAAATTGAAACGTCAT CTTTAGATGGAGAAAACAGAAGAATTCTGATCAATACAGACATTGGATTGCCCAATGGCTTAACCTTTGACCCTTTCTCTAAACTGCTCT GCTGGGCAGATGCAGGAACCAAAAAACTGGAGTGTACACTACCTGATGGAACTGGACGGCGTGTCATTCAAAACAACCTCAAGTACCCCT TCAGCATCGTAAGCTATGCAGATCACTTCTACCACACAGACTGGAGGAGGGATGGTGTTGTATCAGTAAATAAACATAGTGGCCAGTTTA CTGATGAGTATCTCCCAGAACAACGATCTCACCTCTACGGGATAACTGCAGTCTACCCCTACTGCCCAACAGGAAGAAAGTAAGTACAGT AATGTAAAGGAAGACTTGGAGTTTACAATCAGAACCTGGACCCTAAAGAACAGTGACTGCAAAGGCAAAGAAAGTAAAAAAGGAATTGGC CATTAGACGTTCCTGAGCATCCAAGATGAACATTTTGTAGTGCAAAAAGACTTTTGTGAAAAGCTGATACCTCAATCTTTACTACTGTAT TTTTAAAAATGAAGGTTGTTATTGCAAGTTTAAAAAGGTAACAGAATTTTAACTGTTGCTTATTAAAGCAACTTCTTGTAAACATTTATC ATTAATATTTAAAAGATCAAATTCATTCAACTAAGAATTAGAGTTTAAGACTCTAAACCTGATTTTTGCCATGGATTCCTTCTGGCCAAG AAATTAAAGCACATGTGATCAATATAACAATATAATCCTAAACCTTGACAGTTGGAGAAGCCAATGCAGAACTGATGGGAAAGGACCAAT TATTTATAGTTTCCCAACAAAAGTTCTAAGATTTTTTACCTCTGCATCAGTGCATTTCTATTTATATCAAAAGGTGCTAAAATGATTCAA TTTGCATTTTCTGATCCTGTAGTGCCTCTATAGAAGTACCCACAGAAAGTAAAGTATCACATTTATAAATACCAAAGATGTAACAATTTT 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FusionGenePPI for TRDMT1_NID2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TRDMT1 | DDX24, COPS6, RBM48, UTP14A, STX1A, EEF1A1, LRIF1, SETDB1, UNC119, APP, GBE1, NFRKB, SNRPD3, TBC1D2B | NID2 | LAMC1, COL4A1, COL1A1, MDK, HSPG2, ELN, SKIL, KRTAP10-3, LGALS3, TAZ, SUSD4, LGALS9, GPR183, TMEM25, ETV6, OLFM4, PILRA, LYG2, EPHA7, DEFA1, PTPRK |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TRDMT1_NID2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | TRDMT1 | O14717 | DB00738 | Pentamidine | tRNA (cytosine(38)-C(5))-methyltransferase | small molecule | approved|investigational |
| Hgene | TRDMT1 | O14717 | DB09462 | Glycerin | tRNA (cytosine(38)-C(5))-methyltransferase | small molecule | approved|investigational |
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RelatedDiseases for TRDMT1_NID2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | NID2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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