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Fusion gene ID: 39170 |
FusionGeneSummary for TP53_PXDNL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TP53_PXDNL | Fusion gene ID: 39170 | Hgene | Tgene | Gene symbol | TP53 | PXDNL | Gene ID | 7158 | 137902 |
| Gene name | tumor protein p53 binding protein 1 | peroxidasin like | |
| Synonyms | 53BP1|TDRD30|TP53|p202|p53BP1 | PMR1|PRM1|VPO2 | |
| Cytomap | 15q15.3 | 8q11.22-q11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | TP53-binding protein 1p53-binding protein 1tumor protein 53-binding protein, 1tumor suppressor p53-binding protein 1 | peroxidasin-like proteincardiac peroxidasecardiovascular peroxidase 2peroxidasin homolog-likepolysomal ribonuclease 1 homologvascular peroxidase 2 | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | P04637 | A1KZ92 | |
| Ensembl transtripts involved in fusion gene | ENST00000413465, ENST00000359597, ENST00000269305, ENST00000455263, ENST00000420246, ENST00000445888, ENST00000574684, | ENST00000356297, ENST00000543296, | |
| Fusion gene scores | * DoF score | 22 X 7 X 7=1078 | 4 X 3 X 3=36 |
| # samples | 21 | 4 | |
| ** MAII score | log2(21/1078*10)=-2.35989594508638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TP53 [Title/Abstract] AND PXDNL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TP53 | GO:0006303 | double-strand break repair via nonhomologous end joining | 23333306|23760478|28241136 |
| Hgene | TP53 | GO:0006974 | cellular response to DNA damage stimulus | 17500065|28241136 |
| Hgene | TP53 | GO:0045830 | positive regulation of isotype switching | 23345425 |
| Hgene | TP53 | GO:0051260 | protein homooligomerization | 23345425 |
| Hgene | TP53 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination | 23333306|23345425 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A7EF-01A | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000413465 | ENST00000356297 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| Frame-shift | ENST00000413465 | ENST00000543296 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| In-frame | ENST00000359597 | ENST00000356297 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| Frame-shift | ENST00000359597 | ENST00000543296 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| Frame-shift | ENST00000269305 | ENST00000356297 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| In-frame | ENST00000269305 | ENST00000543296 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| In-frame | ENST00000455263 | ENST00000356297 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| Frame-shift | ENST00000455263 | ENST00000543296 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| In-frame | ENST00000420246 | ENST00000356297 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| Frame-shift | ENST00000420246 | ENST00000543296 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| Frame-shift | ENST00000445888 | ENST00000356297 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| In-frame | ENST00000445888 | ENST00000543296 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| intron-3CDS | ENST00000574684 | ENST00000356297 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
| intron-3CDS | ENST00000574684 | ENST00000543296 | TP53 | chr17 | 7577499 | - | PXDNL | chr8 | 52567320 | - |
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FusionProtFeatures for TP53_PXDNL |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TP53 | PXDNL |
| Isoform PMR1: Endonuclease selectively degrading sometarget mRNAs while they are engaged by translating ribosomes,among which albumin and beta-globin mRNAs.{ECO:0000269|PubMed:22543864}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 17_25 | 260 | 394 | Motif | Note=TADI |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 48_56 | 260 | 394 | Motif | Note=TADII |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 17_25 | 260 | 774 | Motif | Note=TADI |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 48_56 | 260 | 774 | Motif | Note=TADII |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 17_25 | 260 | 394 | Motif | Note=TADI |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 48_56 | 260 | 394 | Motif | Note=TADII |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 17_25 | 260 | 755 | Motif | Note=TADI |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 48_56 | 260 | 755 | Motif | Note=TADII |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 1_44 | 260 | 394 | Region | Note=Transcription activation (acidic) |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 1_44 | 260 | 774 | Region | Note=Transcription activation (acidic) |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 1_44 | 260 | 394 | Region | Note=Transcription activation (acidic) |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 1_44 | 260 | 755 | Region | Note=Transcription activation (acidic) |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 1393_1451 | 54 | 1464 | Domain | VWFC |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 180_233 | 54 | 1464 | Domain | Note=LRRCT |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 234_322 | 54 | 1464 | Domain | Note=Ig-like C2-type 1 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 330_414 | 54 | 1464 | Domain | Note=Ig-like C2-type 2 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 419_504 | 54 | 1464 | Domain | Note=Ig-like C2-type 3 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 507_596 | 54 | 1464 | Domain | Note=Ig-like C2-type 4 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 1393_1451 | 54 | 1388 | Domain | VWFC |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 180_233 | 54 | 1388 | Domain | Note=LRRCT |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 234_322 | 54 | 1388 | Domain | Note=Ig-like C2-type 1 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 330_414 | 54 | 1388 | Domain | Note=Ig-like C2-type 2 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 419_504 | 54 | 1388 | Domain | Note=Ig-like C2-type 3 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 507_596 | 54 | 1388 | Domain | Note=Ig-like C2-type 4 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 123_144 | 54 | 1464 | Repeat | Note=LRR 4 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 147_168 | 54 | 1464 | Repeat | Note=LRR 5 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 51_72 | 54 | 1464 | Repeat | Note=LRR 1 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 75_96 | 54 | 1464 | Repeat | Note=LRR 2 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 99_120 | 54 | 1464 | Repeat | Note=LRR 3 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 123_144 | 54 | 1388 | Repeat | Note=LRR 4 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 147_168 | 54 | 1388 | Repeat | Note=LRR 5 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 51_72 | 54 | 1388 | Repeat | Note=LRR 1 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 75_96 | 54 | 1388 | Repeat | Note=LRR 2 |
| Tgene | >PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 99_120 | 54 | 1388 | Repeat | Note=LRR 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 102_292 | 260 | 394 | DNA binding | . |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 102_292 | 260 | 774 | DNA binding | . |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 102_292 | 260 | 394 | DNA binding | . |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 102_292 | 260 | 755 | DNA binding | . |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 305_321 | 260 | 394 | Motif | Note=Bipartite nuclear localization signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 339_350 | 260 | 394 | Motif | Note=Nuclear export signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 370_372 | 260 | 394 | Motif | Note=[KR]-[STA]-K motif |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 305_321 | 260 | 774 | Motif | Note=Bipartite nuclear localization signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 339_350 | 260 | 774 | Motif | Note=Nuclear export signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 370_372 | 260 | 774 | Motif | Note=[KR]-[STA]-K motif |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 305_321 | 260 | 394 | Motif | Note=Bipartite nuclear localization signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 339_350 | 260 | 394 | Motif | Note=Nuclear export signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 370_372 | 260 | 394 | Motif | Note=[KR]-[STA]-K motif |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 305_321 | 260 | 755 | Motif | Note=Bipartite nuclear localization signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 339_350 | 260 | 755 | Motif | Note=Nuclear export signal |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 370_372 | 260 | 755 | Motif | Note=[KR]-[STA]-K motif |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 325_356 | 260 | 394 | Region | Note=Oligomerization |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 368_387 | 260 | 394 | Region | Note=Basic (repression of DNA-binding) |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 325_356 | 260 | 774 | Region | Note=Oligomerization |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 368_387 | 260 | 774 | Region | Note=Basic (repression of DNA-binding) |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 325_356 | 260 | 394 | Region | Note=Oligomerization |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 368_387 | 260 | 394 | Region | Note=Basic (repression of DNA-binding) |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 325_356 | 260 | 755 | Region | Note=Oligomerization |
| Hgene | >TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 368_387 | 260 | 755 | Region | Note=Basic (repression of DNA-binding) |
| Tgene | PXDNL | chr17:7577499 | chr8:52567320 | ENST00000356297 | - | 0 | 23 | 24_50 | 54 | 1464 | Domain | Note=LRRNT |
| Tgene | PXDNL | chr17:7577499 | chr8:52567320 | ENST00000543296 | - | 0 | 21 | 24_50 | 54 | 1388 | Domain | Note=LRRNT |
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FusionGeneSequence for TP53_PXDNL |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TP53_ENST00000413465_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_1670aa MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPS WPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE RCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSRDLRFNRIRE IPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLH NNKLSKIPAGSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVE VPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVI QPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVT PKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFT QLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQ AGDDFVESSILDAVQRVDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDL VSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQPLPPPRLVA TVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRP SATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQESPCFLAGDHRANEH LALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFR FGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR GRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWY ENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDCCADCRSRGQFRAVTQESQKKRSAQYS YPVDKDMELSHLRSRQQDKIYVGEDARNVTVLAKTKFSQDFSTFAAEIQETITALREQINKLEARLRQAGCTDVRGVPRKAEERWMKEDC >In-frame_TP53_ENST00000359597_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_1670aa MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPS WPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE RCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSRDLRFNRIRE IPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLH NNKLSKIPAGSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVE VPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVI QPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVT PKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFT QLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQ AGDDFVESSILDAVQRVDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDL VSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQPLPPPRLVA TVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRP SATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQESPCFLAGDHRANEH LALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFR FGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR GRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWY ENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDCCADCRSRGQFRAVTQESQKKRSAQYS YPVDKDMELSHLRSRQQDKIYVGEDARNVTVLAKTKFSQDFSTFAAEIQETITALREQINKLEARLRQAGCTDVRGVPRKAEERWMKEDC >In-frame_TP53_ENST00000269305_chr17_7577499_-_PXDNL_ENST00000543296_chr8_52567320_-_260aa MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPS WPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE >In-frame_TP53_ENST00000455263_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_1670aa MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPS WPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE RCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSRDLRFNRIRE IPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLH NNKLSKIPAGSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVE VPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVI QPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVT PKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFT QLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQ AGDDFVESSILDAVQRVDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDL VSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQPLPPPRLVA TVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRP SATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQESPCFLAGDHRANEH LALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFR FGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR GRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWY ENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDCCADCRSRGQFRAVTQESQKKRSAQYS YPVDKDMELSHLRSRQQDKIYVGEDARNVTVLAKTKFSQDFSTFAAEIQETITALREQINKLEARLRQAGCTDVRGVPRKAEERWMKEDC >In-frame_TP53_ENST00000420246_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_1670aa MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPS WPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE RCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSRDLRFNRIRE IPGSAFKKLKNLNTLLLNNNHIRKISRNAFEGLENLLYLYLYKNEIHALDKQTFKGLISLEHLYIHFNQLEMLQPETFGDLLRLERLFLH NNKLSKIPAGSFSNLDSLKRLRLDSNALVCDCDLMWLGELLQGFAQHGHTQAAATCEYPRRLHGRAVASVTVEEFNCQSPRITFEPQDVE VPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVI QPQDTEVLIGTSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANIIVQAPPQFTVT PKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAVFT QLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFGLAVTNMFLTVTAIQGRQ AGDDFVESSILDAVQRVDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQLIRERVKQGLTVDLEGKEFRYNDL VSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRAHDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLPVGSRQPLPPPRLVA TVWARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMNTRHADPRGTHAPCMLFARSSPACASGRP SATVDSVYAREQINQQTAYIDGSNVYGSSERESQALRDPSVPRGLLKTGFPWPPSGKPLLPFSTGPPTECARQEQESPCFLAGDHRANEH LALAAMHTLWFREHNRMATELSALNPHWEGNTVYQEARKIVGAELQHITYSHWLPKVLGDPGTRMLRGYRGYNPNVNAGIINSFATAAFR FGHTLINPILYRLNATLGEISEGHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVDSAATIIQR GRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWY ENPGVFTPAQLTQLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQDCCADCRSRGQFRAVTQESQKKRSAQYS YPVDKDMELSHLRSRQQDKIYVGEDARNVTVLAKTKFSQDFSTFAAEIQETITALREQINKLEARLRQAGCTDVRGVPRKAEERWMKEDC >In-frame_TP53_ENST00000445888_chr17_7577499_-_PXDNL_ENST00000543296_chr8_52567320_-_260aa MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPS WPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TP53_ENST00000413465_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5010nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT TCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAA ATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCTGCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTT GAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAATCCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTG GAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCAT AACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGATTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGT GACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCAACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGG AGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAG GTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAACCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTG GATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACTCATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAG TGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATC CAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGAATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACC AGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTCCAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGT CGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGCAGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACC CCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAA ACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGC CAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACT CAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACATTTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGG AATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGATGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGAC CAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGTGACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAA GCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAGAGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCA CAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATT TTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTG GTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCAT GCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAG CCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCC ACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTG GACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCC ATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCC TCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCAAACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAG CGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTG CCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCAT CTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGA AACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCAGCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGAC CCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGTGAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGA TTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCG CTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCC TCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGG GGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAA ATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGAC CTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTAT GAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATT CAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTG TGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGCAGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGC TATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCAACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACA GTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGCGGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAAC AAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGC ACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGA >In-frame_TP53_ENST00000359597_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5010nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT TCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAA ATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCTGCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTT GAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAATCCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTG GAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCAT AACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGATTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGT GACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCAACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGG AGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAG GTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAACCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTG GATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACTCATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAG TGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATC CAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGAATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACC AGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTCCAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGT CGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGCAGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACC CCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAA ACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGC CAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACT CAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACATTTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGG AATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGATGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGAC CAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGTGACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAA GCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAGAGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCA CAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATT TTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTG GTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCAT GCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAG CCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCC ACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTG GACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCC ATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCC TCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCAAACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAG CGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTG CCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCAT CTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGA AACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCAGCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGAC CCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGTGAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGA TTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCG CTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCC TCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGG GGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAA ATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGAC CTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTAT GAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATT CAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTG TGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGCAGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGC TATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCAACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACA GTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGCGGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAAC AAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGC ACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGA >In-frame_TP53_ENST00000269305_chr17_7577499_-_PXDNL_ENST00000543296_chr8_52567320_-_782nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT >In-frame_TP53_ENST00000455263_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5010nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT TCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAA ATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCTGCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTT GAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAATCCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTG GAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCAT AACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGATTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGT GACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCAACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGG AGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAG GTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAACCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTG GATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACTCATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAG TGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATC CAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGAATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACC AGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTCCAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGT CGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGCAGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACC CCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAA ACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGC CAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACT CAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACATTTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGG AATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGATGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGAC CAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGTGACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAA GCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAGAGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCA CAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATT TTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTG GTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCAT GCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAG CCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCC ACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTG GACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCC ATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCC TCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCAAACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAG CGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTG CCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCAT CTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGA AACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCAGCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGAC CCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGTGAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGA TTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCG CTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCC TCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGG GGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAA ATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGAC CTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTAT GAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATT CAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTG TGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGCAGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGC TATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCAACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACA GTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGCGGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAAC AAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGC ACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGA >In-frame_TP53_ENST00000420246_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5010nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT TCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAA ATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCTGCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTT GAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAATCCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTG GAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCAT AACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGATTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGT GACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCAACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGG AGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAG GTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAACCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTG GATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACTCATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAG TGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATC CAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGAATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACC AGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTCCAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGT CGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGCAGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACC CCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAA ACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGC CAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACT CAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACATTTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGG AATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGATGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGAC CAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGTGACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAA GCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAGAGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCA CAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATT TTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTG GTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCAT GCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAG CCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCC ACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTG GACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCC ATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCC TCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCAAACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAG CGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTG CCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCAT CTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGA AACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCAGCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGAC CCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGTGAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGA TTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCG CTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCC TCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGG GGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAA ATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGAC CTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTAT GAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATT CAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTG TGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGCAGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGC TATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCAACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACA GTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGCGGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAAC AAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGC ACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGA >In-frame_TP53_ENST00000445888_chr17_7577499_-_PXDNL_ENST00000543296_chr8_52567320_-_782nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TP53_ENST00000413465_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5322nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT TCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAA ATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCTGCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTT GAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAATCCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTG GAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCAT AACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGATTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGT GACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCAACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGG AGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAG GTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAACCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTG GATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACTCATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAG TGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATC CAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGAATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACC AGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTCCAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGT CGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGCAGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACC CCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAA ACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGC CAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACT CAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACATTTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGG AATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGATGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGAC CAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGTGACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAA GCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAGAGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCA CAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATT TTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTG GTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCAT GCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAG CCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCC ACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTG GACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCC ATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCC TCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCAAACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAG CGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTG CCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCAT CTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGA AACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCAGCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGAC CCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGTGAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGA TTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCG CTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCC TCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGG GGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAA ATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGAC CTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTAT GAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATT CAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTG TGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGCAGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGC TATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCAACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACA GTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGCGGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAAC AAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGC ACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGA ACCTGCTGTCCAGTTTGCAGAGACCGAGGAATGCCAAGTGATTCCCCAGAGAAGCGCTAATAAAAGTTTTGTGCTGTTGAGCCCCAAATG GGAAATTTCTCAGGAAGAGACATTTAGGACTTCAGAACTTTTAACTTGTAGTCACATTGTTGATATGGAAACCACTGACTTAAGCAACTT AGTTCATCTAATCTTACATATACTTACGATCTTTTATTTTTTCATTTTCTAACATACCTTGAAATAATTCAAAACTAAAAGCAATAAAGT GCATATGAAGTGTTTGATCATAAGAAATATTTCTTACTGTAAGCTGTCAGTTTTATATGCCACACCTGGAAATAAAAAGAATATCATGGA >In-frame_TP53_ENST00000359597_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5322nt ATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAAC GTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCA GATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCC TGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAG TCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACA CCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAG CGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAAC ACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGT TCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAA ATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCTGCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTT GAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAATCCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTG GAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCAT AACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGATTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGT GACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCAACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGG AGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAG GTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAACCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTG GATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACTCATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAG TGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATC CAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGAATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACC AGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTCCAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGT CGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGCAGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACC CCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAA ACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGC CAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACT CAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACATTTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGG AATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGATGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGAC CAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGTGACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAA GCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAGAGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCA CAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATT TTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTG GTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCAT GCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAG CCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCC ACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTG GACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCC ATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCC TCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCAAACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAG CGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTG CCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCAT CTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGA AACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCAGCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGAC CCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGTGAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGA TTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCG CTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCC TCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGG GGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAA ATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGAC CTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTAT GAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATT CAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTG TGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGCAGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGC TATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCAACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACA GTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGCGGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAAC AAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGC ACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGA ACCTGCTGTCCAGTTTGCAGAGACCGAGGAATGCCAAGTGATTCCCCAGAGAAGCGCTAATAAAAGTTTTGTGCTGTTGAGCCCCAAATG GGAAATTTCTCAGGAAGAGACATTTAGGACTTCAGAACTTTTAACTTGTAGTCACATTGTTGATATGGAAACCACTGACTTAAGCAACTT AGTTCATCTAATCTTACATATACTTACGATCTTTTATTTTTTCATTTTCTAACATACCTTGAAATAATTCAAAACTAAAAGCAATAAAGT GCATATGAAGTGTTTGATCATAAGAAATATTTCTTACTGTAAGCTGTCAGTTTTATATGCCACACCTGGAAATAAAAAGAATATCATGGA >In-frame_TP53_ENST00000269305_chr17_7577499_-_PXDNL_ENST00000543296_chr8_52567320_-_5261nt GTTTTCCCCTCCCATGTGCTCAAGACTGGCGCTAAAAGTTTTGAGCTTCTCAAAAGTCTAGAGCCACCGTCCAGGGAGCAGGTAGCTGCT GGGCTCCGGGGACACTTTGCGTTCGGGCTGGGAGCGTGCTTTCCACGACGGTGACACGCTTCCCTGGATTGGCAGCCAGACTGCCTTCCG GGTCACTGCCATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCAGGAAACATTTTCAGACCTATGGAAACTACTTCC TGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTCCCCGGACGATATTGAACAATGGTTCACTGAAGA CCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACC AGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGG GACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGT TGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCC CCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGA TGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGGCTCTGACTGTACCACCATCCACTACAACTACAT GTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCACACTGGAAGACTCCAGAGACTTGAGGTTTAACAG AATAAGAGAAATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCTGCTGAACAACAACCACATCAGAAAGATTTCCAG AAATGCTTTTGAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAATCCATGCACTAGATAAGCAAACATTTAAAGGACT CATATCTTTGGAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACT ATTTTTGCATAACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGATTCATTAAAAAGATTGCGTCTGGATTCCAACGC CCTGGTTTGTGACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCAACACGGCCACACCCAGGCTGCGGCTACCTGCGA ATATCCCAGGAGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCA GGATGTGGAGGTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAACCCCAAACCTGAGATTATTTGGATACACAACAA CCACTCATTGGATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACTCATGATCCGAAACACCAGAGAGTCAGACCAAGG TGTCTATCAGTGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAG CTTTGTAATCCAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGAATGTATGGCCACAGGCCACCCACACCCTCTTAT CACTTGGACCAGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTCCAGTGGACTTTACTTACAGAACATCACACAACG GGATCATGGTCGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGCAGCAAACATAATTGTACAAGCTCCTCCACAATT TACAGTAACCCCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGT CTGGACAAAAACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCA CGATCAAGGCCAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGC AGTGTTTACTCAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACATTTCATGTCATGCTCAAGGAGAACCACAGCCCAT AATTACTTGGAATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGATGATGAAGGCACGCTGACTATCTACGACGCAGG GTTCCCTGACCAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGTGACCAACATGTTTCTTACAGTCACGGCTATACA GGGTAGACAAGCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAGAGTTGACAGTGCAATTAACTCCACACGAAGACA TTTGTTTTCACAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGC AGGGGAGATTTTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTA CAATGACTTGGTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCG GTGTTTCCATGCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCG CCTGCTGCAGCCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCG GCTGGTCGCCACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGA GCACGACTTGGACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCC TTGTTTCCCCATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAG CGGCCGTCCCTCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCAAACAGCCTACATCGATGGCTCCAACGTTTACGG GAGCTCGGAGCGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAA GCCCTTATTGCCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGC CAACGAGCATCTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCA CTGGGAGGGAAACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCAGCACATCACCTACAGCCACTGGCTGCCTAAGGT CCTGGGGGACCCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGTGAATGCAGGCATCATTAACTCTTTTGCTACTGC AGCCTTTAGATTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTT CCATAAAGCGCTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATG GCGGGCACCCTCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCAT CATTCAAAGGGGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCT TCAAAATGAAATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTAT GGTTGAAGACCTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAG GTTCTGGTATGAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGG TGACAGCATTCAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGA CCTGCGAGTGTGGCAAGACTGCTGTGCAGATAAACAAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAA GGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGCACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCC CGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGAACCTGCTGTCCAGTTTGCAGAGACCGAGGAATGCCAAGTGATTCCCCAGAGAAGC GCTAATAAAAGTTTTGTGCTGTTGAGCCCCAAATGGGAAATTTCTCAGGAAGAGACATTTAGGACTTCAGAACTTTTAACTTGTAGTCAC ATTGTTGATATGGAAACCACTGACTTAAGCAACTTAGTTCATCTAATCTTACATATACTTACGATCTTTTATTTTTTCATTTTCTAACAT ACCTTGAAATAATTCAAAACTAAAAGCAATAAAGTGCATATGAAGTGTTTGATCATAAGAAATATTTCTTACTGTAAGCTGTCAGTTTTA >In-frame_TP53_ENST00000455263_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5455nt CTAGAGCCACCGTCCAGGGAGCAGGTAGCTGCTGGGCTCCGGGGACACTTTGCGTTCGGGCTGGGAGCGTGCTTTCCACGACGGTGACAC GCTTCCCTGGATTGGCAGCCAGACTGCCTTCCGGGTCACTGCCATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCA GGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTC CCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGC ACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAG CTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCA ACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTC ACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCG AGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGG CTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCAC ACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAAATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCT GCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTTGAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAAT CCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTGGAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGA GACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCATAACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGA TTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGTGACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCA ACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGGAGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAA TTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAGGTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAA CCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTGGATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACT CATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAGTGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCAT GCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATCCAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGA ATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACCAGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTC CAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGTCGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGC AGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACCCCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTG TGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAAACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTC TGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGCCAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTC TGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACTCAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACAT TTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGGAATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGA TGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGACCAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGT GACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAAGCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAG AGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCACAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCC GCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATTTTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCT CACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTGGTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCAC AGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCATGCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCC CACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAGCCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCC TGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCCACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACAC GCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTGGACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCG GCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCCATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCAT GCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCCTCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCA AACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAGCGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCT GAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTGCCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGA GAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCATCTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAG GATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGAAACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCA GCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGACCCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGT GAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGATTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCAC CTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCGCTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGT TCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCCTCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGC TTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGGGGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTG TAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAAATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTC TCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGACCTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGT TACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTATGAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCA GGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATTCAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGA TTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTGTGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGC AGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGCTATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCA ACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACAGTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGC GGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAACAAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGG GGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGCACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGAT TTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGAACCTGCTGTCCAGTTTGCAGAGACCGAGGAATGCCAAGTGATTCCCC AGAGAAGCGCTAATAAAAGTTTTGTGCTGTTGAGCCCCAAATGGGAAATTTCTCAGGAAGAGACATTTAGGACTTCAGAACTTTTAACTT GTAGTCACATTGTTGATATGGAAACCACTGACTTAAGCAACTTAGTTCATCTAATCTTACATATACTTACGATCTTTTATTTTTTCATTT TCTAACATACCTTGAAATAATTCAAAACTAAAAGCAATAAAGTGCATATGAAGTGTTTGATCATAAGAAATATTTCTTACTGTAAGCTGT >In-frame_TP53_ENST00000420246_chr17_7577499_-_PXDNL_ENST00000356297_chr8_52567320_-_5455nt CTAGAGCCACCGTCCAGGGAGCAGGTAGCTGCTGGGCTCCGGGGACACTTTGCGTTCGGGCTGGGAGCGTGCTTTCCACGACGGTGACAC GCTTCCCTGGATTGGCAGCCAGACTGCCTTCCGGGTCACTGCCATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAGTCA GGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCTGTC CCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCCTGC ACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGGCAG CTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTGCCA ACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCAGTC ACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTATCCG AGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGTTGG CTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCATCAC ACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAAATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACTTCT GCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTTGAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGAAAT CCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTGGAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCCAGA GACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCATAACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCTGGA TTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGTGACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGCCCA ACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGGAGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATTCAA TTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAGGTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGGAAA CCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTGGATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCACACT CATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAGTGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGCCAT GCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATCCAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTTGGA ATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACCAGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAACGTC CAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGTCGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGCTGC AGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACCCCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCTCTG TGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAAACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTCCTC TGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGCCAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGTGTC TGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACTCAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAACAT TTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGGAATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGTGGA TGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGACCAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGCTGT GACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAAGCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACAGAG AGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCACAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTACCC GCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATTTTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGGGCT CACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTGGTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATGCAC AGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCATGCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCAGCC CACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAGCCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCTTCC TGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCCACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTACAC GCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTGGACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGGGCG GCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCCATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTGCAT GCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCCTCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCAGCA AACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAGCGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCTCCT GAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTGCCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCAGGA GAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCATCTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAACAG GATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGAAACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCTGCA GCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGACCCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAACGT GAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGATTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGCCAC CTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCGCTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCCGGT TCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCCTCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGCGGC TTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGGGGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTTCTG TAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAAATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGGCTC TCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGACCTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTTTGT TACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTATGAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAAGCA GGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATTCAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACAGGA TTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTGTGGCAAGACTGCTGTGCAGACTGTAGGAGTAGAGGACAGTTCAGAGC AGTGACGCAAGAGTCTCAAAAGAAACGCTCAGCTCAATACAGCTATCCTGTTGATAAGGATATGGAGTTAAGTCATCTAAGAAGTAGGCA ACAAGATAAAATATATGTGGGTGAAGATGCTAGAAATGTGACAGTTCTGGCAAAAACAAAGTTCTCCCAAGATTTCAGCACGTTTGCAGC GGAAATTCAGGAAACCATCACAGCACTCAGAGAGCAGATAAACAAGCTGGAGGCACGCCTGAGGCAGGCAGGGTGTACAGATGTTAGAGG GGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGCACTCACTGCATTTGTGAGAGTGGCCAGGTCACCTGTGTGGTGGAGAT TTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGAACCTGCTGTCCAGTTTGCAGAGACCGAGGAATGCCAAGTGATTCCCC AGAGAAGCGCTAATAAAAGTTTTGTGCTGTTGAGCCCCAAATGGGAAATTTCTCAGGAAGAGACATTTAGGACTTCAGAACTTTTAACTT GTAGTCACATTGTTGATATGGAAACCACTGACTTAAGCAACTTAGTTCATCTAATCTTACATATACTTACGATCTTTTATTTTTTCATTT TCTAACATACCTTGAAATAATTCAAAACTAAAAGCAATAAAGTGCATATGAAGTGTTTGATCATAAGAAATATTTCTTACTGTAAGCTGT >In-frame_TP53_ENST00000445888_chr17_7577499_-_PXDNL_ENST00000543296_chr8_52567320_-_5207nt AAAAGTCTAGAGCCACCGTCCAGGGAGCAGGTAGCTGCTGGGCTCCGGGGACACTTTGCGTTCGGGCTGGGAGCGTGCTTTCCACGACGG TGACACGCTTCCCTGGATTGGCCAGACTGCCTTCCGGGTCACTGCCATGGAGGAGCCGCAGTCAGATCCTAGCGTCGAGCCCCCTCTGAG TCAGGAAACATTTTCAGACCTATGGAAACTACTTCCTGAAAACAACGTTCTGTCCCCCTTGCCGTCCCAAGCAATGGATGATTTGATGCT GTCCCCGGACGATATTGAACAATGGTTCACTGAAGACCCAGGTCCAGATGAAGCTCCCAGAATGCCAGAGGCTGCTCCCCCCGTGGCCCC TGCACCAGCAGCTCCTACACCGGCGGCCCCTGCACCAGCCCCCTCCTGGCCCCTGTCATCTTCTGTCCCTTCCCAGAAAACCTACCAGGG CAGCTACGGTTTCCGTCTGGGCTTCTTGCATTCTGGGACAGCCAAGTCTGTGACTTGCACGTACTCCCCTGCCCTCAACAAGATGTTTTG CCAACTGGCCAAGACCTGCCCTGTGCAGCTGTGGGTTGATTCCACACCCCCGCCCGGCACCCGCGTCCGCGCCATGGCCATCTACAAGCA GTCACAGCACATGACGGAGGTTGTGAGGCGCTGCCCCCACCATGAGCGCTGCTCAGATAGCGATGGTCTGGCCCCTCCTCAGCATCTTAT CCGAGTGGAAGGAAATTTGCGTGTGGAGTATTTGGATGACAGAAACACTTTTCGACATAGTGTGGTGGTGCCCTATGAGCCGCCTGAGGT TGGCTCTGACTGTACCACCATCCACTACAACTACATGTGTAACAGTTCCTGCATGGGCGGCATGAACCGGAGGCCCATCCTCACCATCAT CACACTGGAAGACTCCAGAGACTTGAGGTTTAACAGAATAAGAGAAATTCCAGGGAGCGCCTTCAAGAAACTCAAGAATTTGAACACACT TCTGCTGAACAACAACCACATCAGAAAGATTTCCAGAAATGCTTTTGAAGGACTTGAAAATTTGCTATATCTGTACCTGTATAAGAATGA AATCCATGCACTAGATAAGCAAACATTTAAAGGACTCATATCTTTGGAACATCTGTATATTCATTTCAACCAACTAGAAATGCTACAGCC AGAGACCTTTGGAGACCTTCTGAGATTAGAGCGACTATTTTTGCATAACAACAAATTATCTAAAATTCCAGCTGGGAGCTTTTCTAATCT GGATTCATTAAAAAGATTGCGTCTGGATTCCAACGCCCTGGTTTGTGACTGTGATCTGATGTGGCTGGGGGAGCTTTTACAAGGCTTTGC CCAACACGGCCACACCCAGGCTGCGGCTACCTGCGAATATCCCAGGAGACTCCATGGGCGTGCAGTTGCTTCAGTAACAGTAGAGGAATT CAATTGCCAGAGCCCCCGAATTACTTTTGAGCCGCAGGATGTGGAGGTACCATCAGGAAATACCGTCTACTTCACCTGCCGGGCGGAAGG AAACCCCAAACCTGAGATTATTTGGATACACAACAACCACTCATTGGATTTGGAAGATGATACTCGACTTAATGTGTTTGATGATGGCAC ACTCATGATCCGAAACACCAGAGAGTCAGACCAAGGTGTCTATCAGTGCATGGCCAGAAATTCCGCTGGGGAAGCCAAGACACAGAGTGC CATGCTCAGATACTCCAGTCTTCCAGCCAAACCAAGCTTTGTAATCCAGCCTCAGGACACAGAGGTTTTAATTGGCACCAGCACAACTTT GGAATGTATGGCCACAGGCCACCCACACCCTCTTATCACTTGGACCAGGGACAATGGATTGGAGCTGGATGGATCCAGGCACGTGGCAAC GTCCAGTGGACTTTACTTACAGAACATCACACAACGGGATCATGGTCGATTTACCTGTCATGCCAACAATAGCCACGGCACTGTTCAAGC TGCAGCAAACATAATTGTACAAGCTCCTCCACAATTTACAGTAACCCCCAAGGATCAAGTGGTGCTGGAAGAACATGCTGTAGAGTGGCT CTGTGAAGCTGACGGCAACCCACCTCCTGTTATTGTCTGGACAAAAACAGGAGGGCAGCTCCCTGTGGAAGGCCAGCATACAGTTCTCTC CTCTGGCACTTTGAGAATTGACCGTGCAGCACAGCACGATCAAGGCCAATATGAATGTCAAGCAGTCAGTTCGTTGGGGGTGAAAAAGGT GTCTGTGCAGCTGACTGTAAAACCCAAAGCTCTTGCAGTGTTTACTCAACTTCCTCAGGATACAAGTGTCGAGGTTGGAAAGAATATAAA CATTTCATGTCATGCTCAAGGAGAACCACAGCCCATAATTACTTGGAATAAGGAAGGTGTGCAGATTACTGAGAGTGGTAAATTCCATGT GGATGATGAAGGCACGCTGACTATCTACGACGCAGGGTTCCCTGACCAGGGAAGATATGAATGTGTGGCTCGGAATTCTTTTGGCCTTGC TGTGACCAACATGTTTCTTACAGTCACGGCTATACAGGGTAGACAAGCTGGCGATGACTTTGTTGAATCTTCCATTCTTGATGCTGTACA GAGAGTTGACAGTGCAATTAACTCCACACGAAGACATTTGTTTTCACAAAAACCTCACACCTCCAGTGACCTGCTGGCTCAATTTCATTA CCCGCGTGACCCACTGATTGTGGAAATGGCAAGAGCAGGGGAGATTTTTGAGCACACGCTGCAGCTGATACGGGAACGTGTGAAGCAGGG GCTCACTGTGGACTTGGAAGGCAAAGAATTCCGGTACAATGACTTGGTGTCCCCGCGCTCCCTCAGCCTCATCGCCAATTTATCTGGATG CACAGCTCGCAGGCCTCTGCCAAACTGCTCCAACCGGTGTTTCCATGCGAAGTACCGCGCCCACGACGGCACGTGCAACAACCTGCAGCA GCCCACGTGGGGCGCGGCGCTGACCGCCTTCGCGCGCCTGCTGCAGCCAGCCTACCGGGACGGCATCCGCGCGCCCCGCGGGCTCGGCCT TCCTGTGGGCTCCCGCCAGCCCCTCCCGCCGCCCCGGCTGGTCGCCACAGTGTGGGCGCGCGCGGCGGCCGTCACCCCCGACCACAGCTA CACGCGCATGCTCATGCACTGGGGCTGGTTTCTAGAGCACGACTTGGACCACACAGTGCCTGCGCTGAGCACAGCCCGCTTCTCGGATGG GCGGCCGTGCAGCTCCGTCTGCACCAACGACCCTCCTTGTTTCCCCATGAACACCCGGCACGCCGACCCCCGGGGCACCCACGCGCCCTG CATGCTCTTCGCGCGCTCCAGCCCCGCGTGTGCCAGCGGCCGTCCCTCTGCGACGGTGGATTCAGTCTATGCACGAGAGCAGATCAACCA GCAAACAGCCTACATCGATGGCTCCAACGTTTACGGGAGCTCGGAGCGGGAATCCCAGGCTCTCAGAGACCCTTCGGTGCCTCGGGGTCT CCTGAAGACAGGCTTTCCTTGGCCTCCCTCCGGAAAGCCCTTATTGCCCTTTTCTACAGGCCCACCCACCGAGTGCGCGCGACAGGAGCA GGAGAGCCCCTGTTTCCTGGCCGGGGACCACCGGGCCAACGAGCATCTGGCTCTGGCCGCCATGCACACCCTGTGGTTCCGGGAACACAA CAGGATGGCCACGGAGCTGTCCGCCCTGAACCCCCACTGGGAGGGAAACACGGTTTACCAGGAAGCCAGGAAGATCGTGGGCGCGGAGCT GCAGCACATCACCTACAGCCACTGGCTGCCTAAGGTCCTGGGGGACCCTGGCACTAGGATGCTGAGGGGTTACCGAGGCTACAACCCCAA CGTGAATGCAGGCATCATTAACTCTTTTGCTACTGCAGCCTTTAGATTTGGCCACACATTAATCAATCCTATTCTTTACCGACTGAATGC CACCTTAGGTGAAATTTCCGAAGGCCACCTTCCGTTCCATAAAGCGCTCTTTTCACCGTCCAGAATAATCAAGGAAGGTGGGATAGACCC GGTTCTCCGGGGGCTGTTTGGCGTGGCTGCTAAATGGCGGGCACCCTCCTACCTTCTCAGTCCTGAGCTGACCCAGAGGCTCTTCTCCGC GGCTTATTCTGCGGCCGTGGATTCGGCTGCCACCATCATTCAAAGGGGTAGAGACCACGGGATCCCACCATATGTTGACTTCAGAGTTTT CTGTAATTTGACTTCAGTTAAGAACTTTGAGGATCTTCAAAATGAAATTAAAGATTCAGAGATTAGACAAAAACTGAGAAAGTTGTACGG CTCTCCAGGTGACATTGACCTCTGGCCCGCCCTTATGGTTGAAGACCTGATTCCTGGTACAAGAGTGGGACCAACACTTATGTGCCTGTT TGTTACCCAGTTTCAGCGGCTAAGAGATGGAGATAGGTTCTGGTATGAAAACCCTGGAGTATTTACCCCGGCACAACTCACTCAGCTGAA GCAGGCGTCCCTGAGCCGGGTGCTTTGTGACAATGGTGACAGCATTCAGCAAGTGCAGGCTGATGTCTTTGTAAAGGCAGAATACCCACA GGATTACCTGAACTGCAGCGAGATCCCGAAGGTGGACCTGCGAGTGTGGCAAGACTGCTGTGCAGATAAACAAGCTGGAGGCACGCCTGA GGCAGGCAGGGTGTACAGATGTTAGAGGGGTTCCAAGGAAGGCCGAGGAGCGCTGGATGAAAGAAGACTGCACTCACTGCATTTGTGAGA GTGGCCAGGTCACCTGTGTGGTGGAGATTTGTCCCCCGGCTCCCTGTCCCAGTCCTGAATTGGTGAAAGGAACCTGCTGTCCAGTTTGCA GAGACCGAGGAATGCCAAGTGATTCCCCAGAGAAGCGCTAATAAAAGTTTTGTGCTGTTGAGCCCCAAATGGGAAATTTCTCAGGAAGAG ACATTTAGGACTTCAGAACTTTTAACTTGTAGTCACATTGTTGATATGGAAACCACTGACTTAAGCAACTTAGTTCATCTAATCTTACAT ATACTTACGATCTTTTATTTTTTCATTTTCTAACATACCTTGAAATAATTCAAAACTAAAAGCAATAAAGTGCATATGAAGTGTTTGATC |
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FusionGenePPI for TP53_PXDNL |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TP53 | WWOX, CDC14A, MAGEB18, DVL2, TP53BP1, BAK1, ATM, BLM, BRCA1, ATR, TFAP2A, EPHA3, BARD1, RAD51, BRCA2, BRE, BRCC3, MDM2, TP53, RPA1, CHEK1, AR, PRKDC, S100B, SFN, TFAP2C, CDKN1A, LINC01194, EP300, PRMT1, CARM1, ANKRD2, YBX1, APTX, PARP1, XRCC1, CABLES2, CABLES1, RPL11, CDKN2A, MDC1, PHB, MTA1, MTA2, PML, EEF2, TP53INP1, ING4, ING5, HIPK1, TP53RK, RCHY1, UBE2A, PTEN, RRM2B, RRM2, HIF1A, HDAC1, CREBBP, SMARCB1, SMARCA4, SMARCC1, SUMO1, UBE2I, CHD3, HIPK3, TDG, TADA3, CREB1, HIPK2, KAT2B, KIAA0087, RAB4A, THAP8, CCDC106, FAM173A, S100A8, ZCCHC10, ANXA3, ARL3, ATF3, BCR, CCT5, COX17, DLEU1, FXYD6, GSTM4, HSPB1, PNP, STX5, WDR33, ARIH2, BTBD2, CCL18, CDC42, EIF2S2, LAMA4, MAD2L1BP, MPHOSPH6, PAFAH1B3, PCDHA4, PPA1, PSMD11, SAT1, SERPINB9, SNRPN, SULT1E1, TK1, CDKN2C, ERH, ZNF24, PLAGL1, THRB, ELL, E4F1, ABL1, GSK3B, HSP90AA1, TOP1, BRF1, ESR1, EIF2AK2, S100A4, HMGB1, APEX1, HNF4A, NDN, PLK3, HTT, PTGS2, AURKA, RFC1, CDK1, CDK2, CCNA2, PIN1, GPS2, CCNG1, YWHAZ, MDM4, TFDP1, NFKBIA, ZNF148, PPP1R13L, MED1, WRN, TBP, CDC14B, STK11, MED17, IFI16, GTF2H1, PIAS1, EFEMP2, ERCC3, ERCC2, ERCC6, MAPK8, MAPK9, MAPK10, CEBPZ, PPP4C, NCL, TSG101, TAF1, BAG1, TOP2A, TOP2B, CDK9, EGR1, PRKRIR, CDK7, MNAT1, GNL3, TAF1B, TAF1A, TAF1C, MAPK3, MAPK1, TOPORS, USP7, HSPA9, ING1, POLA1, SMN1, TEP1, CCNH, TP53BP2, KPNB1, HSPA8, WT1, PTTG1, TAF9, CUL9, NR3C1, FKBP3, RYBP, AIMP2, UCHL1, CFLAR, ITCH, DHFR, CCAR1, PSME3, HSPA4, STUB1, PTK2, NUMB, SERPINH1, COPS5, VRK1, ZMIZ1, ZMIZ2, CDK5, ZMYND11, KAT7, ETHE1, CHD8, DAPK1, TXN, OTUD5, USP11, USP39, WDR48, PADI4, NR4A1, FBXO11, UBE2N, HDAC2, SP1, STAT6, TAF6, RFWD2, ADH5, AGBL2, ASF1A, ASPM, BRD8, NPRL3, TRAPPC11, DAB2IP, DNAJB6, DPH1, AGO1, AGO2, GTPBP4, IGF2BP1, LOC613037, LRPPRC, MTHFSD, MYL9, PIWIL1, RNF38, SMARCD2, SPSB1, TRMT11, TTLL5, CUL7, BANP, RNF20, ZBTB7A, KAT8, PSMD10, SMYD2, SETD7, BACH1, MAFK, NCOR1, KAT6A, XRCC6, CTBP1, MAGEA2, NPM1, KAT5, RPL5, RPL23, YY1, VRK2, SETD2, VHL, RAD23A, HABP4, SERBP1, ZBTB2, ZNF420, KDM1A, H2AFX, SP3, TRRAP, MSH2, ING2, KMT2A, RBBP5, MEN1, WDR5, NFYA, NFYB, HECW2, CHEK2, PHF1, KAT2A, TAF5L, SUPT3H, SUPT7L, TADA1, TADA2A, TAF10, SIRT1, SIN3A, PRAM1, PIAS2, DNMT1, KMT2E, RB1CC1, PRDM2, EHMT1, HMGA1, USP29, VDR, UBE3A, EHMT2, NOC2L, AURKB, SIVA1, MDH1, RNF34, RFFL, HDAC9, G3BP1, G3BP2, KPNA4, TRIM24, L3MBTL1, PSMC5, ZNF668, USP10, UBR5, GNL3L, SETD8, IKBKB, BTRC, MSL2, RYK, UIMC1, NUB1, SKI, SOX4, CDK8, MED21, UBE4B, BAIAP2L1, TTK, DAXX, IGF1R, RFWD3, RPS7, HDAC5, HUWE1, RPS3, PSMC3, PSMD4, UHRF2, FBXO42, USP42, SMURF1, NOTCH4, UTP14A, CSNK1A1, HSPA5, ZNHIT1, SYVN1, OTUB1, PDLIM7, APOH, BMP1, SENP3, UFD1L, RAP1B, BCL2L1, RCC1, ANXA7, GADD45A, TPT1, HSPA1A, USO1, SMAD2, SMAD3, RPL26, TRIM27, BCL2, TRIAP1, TRIM28, PRMT3, AXIN1, SIN3B, AGT, MSH6, SET, ARID1A, ETS1, ETS2, ACTL6A, CSNK2B, MAPK14, MAP9, NR0B2, NCOA1, NCOA3, SIRT7, KDM4D, COPS2, SMARCD1, EWSR1, CCDC8, UBE2B, RANBP2, RPS10, LYN, PPARGC1A, HECW1, GAPDH, SRSF1, CRYAB, FBXO4, CUL4A, DTL, PCNA, RB1, PPP1CC, RNF43, CSNK2A1, PRKD1, GPS1, DHCR24, TP63, PRKCD, NQO1, TFAP4, PIAS4, ZHX1, DMTF1, HEXIM1, MUL1, TSC22D1, UBD, ANG, PDCD5, MIF, ITPK1, TXNRD1, MAP3K1, ERCC8, ARID3A, CSNK1D, VPRBP, ELAVL1, TAF5, ERBB4, PLK1, CASP8, SCAMP1, HRAS, MAGED2, UBE2M, DAPK3, SOCS1, SMAD7, PARK7, SMAD1, BMI1, RING1, RNF2, MUC1, ECT2, TRIM39, HNRNPK, NABP2, TWIST1, PHF20, HECTD3, VCP, EP400, MYC, SNAI1, MTOR, TNFAIP3, MKRN1, PPP1CA, TMED9, RNF39, TRIM8, BHLHE40, RABL6, PAN2, ANXA2, MYBBP1A, GTF2H4, RPS26, ECD, TXNIP, UBE2K, FCAMR, GPX2, SQSTM1, PSMB3, ANK2, NCOA2, CLK3, ICK, CREBZF, C10orf90, RPS27A, XPC, PSMD6, CUL4B, PTTG1IP, HERC2, DNAJB1, ZBTB16, NLK, MCL1, BCL2L2, RUNX2, ATRX, RNF128, TNK2, DNAJC7, ZBTB8A, PATZ1, MVP, MAPK7, ABR, ACSL4, ACTA2, ACTB, AIFM2, AKAP12, ATP5A1, BAG2, PRRC2A, PRRC2C, CAD, CAPN1, CCT2, CCT3, CCT4, CCT6A, CCT7, CCT8, CEP55, CPNE7, CRTC2, TUBB, DDB1, DDX5, DGCR14, DNAJA1, DNAJA2, DOCK7, EBNA1BP2, EEF1A1, EIF4E2, ENAH, MRPS18B, RCN2, RPL24, EXOSC7, EXOSC8, MZT2B, FAU, FBL, FBXO21, FTH1, MOGS, GIGYF2, GPATCH8, GRWD1, GTF3C3, GTF3C4, RPL27AP6, HECTD1, HNRNPA1, HNRNPA2B1, HNRNPF, HNRNPH1, HNRNPM, HNRNPU, HPCA, HSP90AB1, HSPA1L, IDH3B, IGF2BP3, ARHGEF17, IQGAP1, IRS4, ITPKC, RPS15P2, LY6G5B, MFAP4, MRPL24, MRPL38, MRPL39, MRPL41, MRPS14, MRPS2, MRPS22, MRPS23, MRPS25, MRPS27, MRPS28, MRPS5, MRPS9, OBSL1, RPL13, PABPC1, PCBP1, PCMT1, PDCD6, PHKA2, PHKB, PHKG2, POLDIP2, PPFIBP1, PPP3CA, PPP3R1, PTCD3, RAE1, RAVER1, RBBP4, RBBP7, RBX1, RDH13, RFC3, RFC4, TRMT10C, RPL7A, RPL10A, RPL10L, RPL12, RPL14, RPL15, RPL18, RPL18A, RPL19, RPL21, RPL23A, RPL26L1, RPL27, RPL3, RPL30, RPL31, RPL37A, RPL4, RPL6, RPL7, RPL8, RPLP0, RPLP2, RPRD1A, RPS14, RPS15, RPS17, RPS2, RPS24, RPS25, RPS27, RPS3A, RPS6, RPS8, RPS9, RRP1B, SART1, SCO2, SF3B2, SKP1, SLC2A12, SNRPD3, SNW1, SUPT6H, TBC1D4, TCEAL4, TCP1, TFRC, TIMM50, TOR1AIP2, TUBA1A, TUBA1C, TUBA4A, TUBB2A, TUBB4B, TUBG1, UBB, UBR4, VASP, VAT1, DCAF7, YTHDF1, YWHAE, ZWINT, SNAI2, PER2, TRIM59, TSC22D3, UBC, TRIM32, HSPA1B, HSPA2, HSPA6, BAG5, RBM3, RBM39, SRSF6, DDX3X, ACTBL2, TUBA8, MYH9, MYLK, MYO1C, MYO6, TPM1, TPM3, TPM4, CAPZB, GSN, VIM, CKAP4, CORO1C, DBN1, FLNA, LIMA1, LMNA, RPL28, RPS4X, RPS13, RPS16, RPS18, RPS19, HNRNPL, ALYREF, CALD1, CHMP4B, CLTA, CLTB, CLTC, DHRS4, EIF5B, GNB2, GTF2I, HADHB, KCTD17, LSM14A, LYZ, NME4, PPP1R12A, PRMT5, SLC25A5, THRAP3, WDR77, MAP1LC3B, FAM175B, XAF1, FZR1, SENP1, PPP1R13B, RELA, CHUK, CXXC1, ASH2L, SETD1A, WDR82, S100A6, ZNF302, IRF7, RANBP9, CAPG, NMT1, NMT2, BCL6, NABP1, NEIL3, PADI1, TOP1MT, YY2, ZIC3, TCF4, SRPK1, SAFB, SAFB2, MAPKAPK5, KDM6A, ABCE1, CELA2B, TCEAL1, BRD7, HERC5, SRC, ZBTB33, GUCY1A3, COPS4, BIRC6, FBXW11, TFAP2B, KLF5, AAGAB, ACVR1C, ADAM28, ARMCX5, ARPP21, CENPA, CLCA3P, CPA5, CYP20A1, C12orf49, DCLRE1C, DDX50, DKK2, DOT1L, DPP6, DZIP1, EGFR, ELL3, EPG5, ETV1, EXOSC4, RMDN1, FHIT, GABRG3, GFPT2, GK2, GOLGA2P5, GPSM3, GRIN2B, HAUS1, HAUS4, HINT3, HOXA9, HYAL4, IL1A, CXCL8, IMP3, INSIG1, IRX1, JMJD8, KLHL40, KLRF1, LAPTM5, LAP3, LGI4, MCM8, MED8, MED22, MFSD12, MIA2, MORN2, MYBPC1, MYOT, NEUROG2, NT5C3A, PACRG, PDIA5, PHYH, PKIA, PLAC8, POLD3, POLR1D, PRPF6, PSD3, PTX3, PURG, RECQL5, RETNLB, RNASE4, RPL36P14, RPUSD4, SACS, SAMD7, SBF2, SEC63, SLAMF1, SLC7A2, SNX12, SPESP1, STAM2, STT3B, STXBP4, STX2, TBC1D24, THAP1, NELFCD, TMEM200A, TOM1L1, TTC28, UBQLN2, UMPS, USH2A, USP1, ZNF300, ZNF619, ZNF763, TERT, RBBP6, PLCG2, CRK, APPL1, ZBTB17, UBE2Q1, OFD1, SSX2IP, CEP120, CEP152, SPICE1, CEP128, CEP135, NINL, NIN, RPGRIP1L, HINFP, RNF125, FOXO3, PPP2R5C, BAX, PPP2R1A, STK4, CSNK1E, TP73, GLI1, NFATC1, SMARCA5, FBXW8, MOV10, NPAS3, PES1, POLRMT, RNASEL, RPA2, RPL29P11, SMG5, FOXA3, FOXB1, FOXC1, FOXG1, FOXJ3, FOXK1, FOXK2, REV1, HSP90B1, BRINP1, FOXN1, FOXP1, FOXQ1, FOXS1, TFIP11, ERN1, DNMT3L, UHRF1, LAMTOR5, TGM2, NAT10, CCND1, USP24, GMPS, NR1I2, TRIM65, BCL2L12, DGKZ, TSNAX, KIF2A, CDKN1C, HBB, EEA1, GLTSCR2, LRRK2, POLI, ATXN3, USP15, CYLD, USP21, STAMBP, KIT, NGFR, HYPK, TRAF6, SMG7, BECN1, TBPL1, MSI2, OTUD1, FBXW7, FAM111A, GPR156, RORC, HOMER3, HR, OLIG2, KDR, AIPL1, DACH1, DLST, PDHA1, RBPJ, CETP, ACKR3, RAB7A, SLC9A9, STARD10, UBE2V2, ZNF679, ZNF839, HEY1, TRIM45, PARK2, YWHAB | PXDNL | CUL3, CSPP1, CARM1, CUTA, SPTAN1, OSTF1, PPP1R16B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 1_83 | 260 | 394 | HRMT1L2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 1_83 | 260 | 774 | HRMT1L2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 1_83 | 260 | 394 | HRMT1L2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 1_83 | 260 | 755 | HRMT1L2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 241_248 | 260 | 394 | the 53BP2 SH3 domain |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 241_248 | 260 | 774 | the 53BP2 SH3 domain |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 241_248 | 260 | 394 | the 53BP2 SH3 domain |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 241_248 | 260 | 755 | the 53BP2 SH3 domain |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 66_110 | 260 | 394 | WWOX |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 66_110 | 260 | 774 | WWOX |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 66_110 | 260 | 394 | WWOX |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 66_110 | 260 | 755 | WWOX |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 116_292 | 260 | 394 | AXIN1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 116_292 | 260 | 774 | AXIN1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 116_292 | 260 | 394 | AXIN1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 116_292 | 260 | 755 | AXIN1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 300_393 | 260 | 394 | CARM1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 300_393 | 260 | 774 | CARM1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 300_393 | 260 | 394 | CARM1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 300_393 | 260 | 755 | CARM1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 1_320 | 260 | 394 | CCAR2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 1_320 | 260 | 774 | CCAR2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 1_320 | 260 | 394 | CCAR2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 1_320 | 260 | 755 | CCAR2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 273_280 | 260 | 394 | DNA |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 273_280 | 260 | 774 | DNA |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 273_280 | 260 | 394 | DNA |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 273_280 | 260 | 755 | DNA |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 256_294 | 260 | 394 | E4F1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 256_294 | 260 | 774 | E4F1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 256_294 | 260 | 394 | E4F1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 256_294 | 260 | 755 | E4F1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 100_370 | 260 | 394 | HIPK1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 100_370 | 260 | 774 | HIPK1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 100_370 | 260 | 394 | HIPK1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 100_370 | 260 | 755 | HIPK1 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 319_360 | 260 | 394 | HIPK2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 319_360 | 260 | 774 | HIPK2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 319_360 | 260 | 394 | HIPK2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 319_360 | 260 | 755 | HIPK2 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000269305 | - | 7 | 11 | 359_363 | 260 | 394 | USP7 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000420246 | - | 7 | 12 | 359_363 | 260 | 774 | USP7 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000445888 | - | 7 | 11 | 359_363 | 260 | 394 | USP7 |
| Hgene | TP53 | chr17:7577499 | chr8:52567320 | ENST00000455263 | - | 7 | 12 | 359_363 | 260 | 755 | USP7 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for TP53_PXDNL |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | TP53 | P04637 | DB01593 | Zinc | Cellular tumor antigen p53 | small molecule | approved|investigational |
| Hgene | TP53 | P04637 | DB00945 | Acetylsalicylic acid | Cellular tumor antigen p53 | small molecule | approved|vet_approved |
Top |
RelatedDiseases for TP53_PXDNL |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | TP53 | C1835398 | LI-FRAUMENI SYNDROME 1 | 19 | CTD_human;UNIPROT |
| Hgene | TP53 | C0009404 | Colorectal Neoplasms | 8 | CTD_human |
| Hgene | TP53 | C0033578 | Prostatic Neoplasms | 6 | CTD_human;HPO |
| Hgene | TP53 | C2239176 | Liver carcinoma | 6 | CTD_human;HPO |
| Hgene | TP53 | C0024121 | Lung Neoplasms | 5 | CTD_human |
| Hgene | TP53 | C1458155 | Mammary Neoplasms | 5 | CTD_human |
| Hgene | TP53 | C0005695 | Bladder Neoplasm | 4 | CTD_human |
| Hgene | TP53 | C0007134 | Renal Cell Carcinoma | 4 | CTD_human;HPO |
| Hgene | TP53 | C0001418 | Adenocarcinoma | 3 | CTD_human |
| Hgene | TP53 | C0007117 | Basal cell carcinoma | 3 | CTD_human |
| Hgene | TP53 | C0007131 | Non-Small Cell Lung Carcinoma | 3 | CTD_human |
| Hgene | TP53 | C0009375 | Colonic Neoplasms | 3 | CTD_human;HPO |
| Hgene | TP53 | C0017638 | Glioma | 3 | CTD_human |
| Hgene | TP53 | C0025202 | melanoma | 3 | CTD_human |
| Hgene | TP53 | C0206686 | Adrenocortical carcinoma | 3 | CTD_human;HPO;ORPHANET |
| Hgene | TP53 | C0001969 | Alcoholic Intoxication | 2 | PSYGENET |
| Hgene | TP53 | C0001973 | Alcoholic Intoxication, Chronic | 2 | PSYGENET |
| Hgene | TP53 | C0007137 | Squamous cell carcinoma | 2 | CTD_human |
| Hgene | TP53 | C0014859 | Esophageal Neoplasms | 2 | CTD_human |
| Hgene | TP53 | C0016978 | gallbladder neoplasm | 2 | CTD_human |
| Hgene | TP53 | C0023903 | Liver neoplasms | 2 | CTD_human |
| Hgene | TP53 | C0036920 | Sezary Syndrome | 2 | CTD_human |
| Hgene | TP53 | C0038356 | Stomach Neoplasms | 2 | CTD_human;HPO |
| Hgene | TP53 | C0149925 | Small cell carcinoma of lung | 2 | CTD_human;ORPHANET |
| Hgene | TP53 | C0311375 | Arsenic Poisoning | 2 | CTD_human |
| Hgene | TP53 | C0001430 | Adenoma | 1 | CTD_human |
| Hgene | TP53 | C0001624 | Adrenal Gland Neoplasms | 1 | CTD_human |
| Hgene | TP53 | C0002736 | Amyotrophic Lateral Sclerosis | 1 | CTD_human |
| Hgene | TP53 | C0004698 | Balkan Nephropathy | 1 | CTD_human |
| Hgene | TP53 | C0007138 | Carcinoma, Transitional Cell | 1 | CTD_human |
| Hgene | TP53 | C0007194 | Hypertrophic Cardiomyopathy | 1 | CTD_human |
| Hgene | TP53 | C0007273 | Carotid Artery Diseases | 1 | CTD_human |
| Hgene | TP53 | C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
| Hgene | TP53 | C0007786 | Brain Ischemia | 1 | CTD_human |
| Hgene | TP53 | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Hgene | TP53 | C0011303 | Demyelinating Diseases | 1 | CTD_human |
| Hgene | TP53 | C0011853 | Diabetes Mellitus, Experimental | 1 | CTD_human |
| Hgene | TP53 | C0013990 | Pathological accumulation of air in tissues | 1 | CTD_human |
| Hgene | TP53 | C0018923 | Hemangiosarcoma | 1 | CTD_human |
| Hgene | TP53 | C0020538 | Hypertensive disease | 1 | CTD_human |
| Hgene | TP53 | C0021361 | Female infertility | 1 | CTD_human |
| Hgene | TP53 | C0021364 | Male infertility | 1 | CTD_human |
| Hgene | TP53 | C0022116 | Ischemia | 1 | CTD_human |
| Hgene | TP53 | C0022593 | Keratosis | 1 | CTD_human |
| Hgene | TP53 | C0022783 | Vulvar Lichen Sclerosus | 1 | CTD_human |
| Hgene | TP53 | C0023434 | Chronic Lymphocytic Leukemia | 1 | CTD_human;ORPHANET |
| Hgene | TP53 | C0023897 | Liver Diseases, Parasitic | 1 | CTD_human |
| Hgene | TP53 | C0023904 | Liver Neoplasms, Experimental | 1 | CTD_human |
| Hgene | TP53 | C0024117 | Chronic Obstructive Airway Disease | 1 | CTD_human |
| Hgene | TP53 | C0024809 | Marijuana Abuse | 1 | PSYGENET |
| Hgene | TP53 | C0026640 | Mouth Neoplasms | 1 | CTD_human |
| Hgene | TP53 | C0027627 | Neoplasm Metastasis | 1 | CTD_human |
| Hgene | TP53 | C0029463 | Osteosarcoma | 1 | CTD_human;HPO |
| Hgene | TP53 | C0030849 | Penile Neoplasms | 1 | CTD_human |
| Hgene | TP53 | C0032578 | Polyploidy | 1 | CTD_human |
| Hgene | TP53 | C0033860 | Psoriasis | 1 | CTD_human |
| Hgene | TP53 | C0036341 | Schizophrenia | 1 | CTD_human |
| Hgene | TP53 | C0037286 | Skin Neoplasms | 1 | CTD_human;HPO |
| Hgene | TP53 | C0040100 | Thymoma | 1 | CTD_human |
| Hgene | TP53 | C0040136 | Thyroid Neoplasm | 1 | CTD_human |
| Hgene | TP53 | C0042065 | Genitourinary Neoplasms | 1 | CTD_human |
| Hgene | TP53 | C0042076 | Urologic Neoplasms | 1 | CTD_human |
| Hgene | TP53 | C0079772 | T-Cell Lymphoma | 1 | CTD_human |
| Hgene | TP53 | C0079773 | Lymphoma, T-Cell, Cutaneous | 1 | CTD_human |
| Hgene | TP53 | C0085136 | Central Nervous System Neoplasms | 1 | CTD_human |
| Hgene | TP53 | C0085390 | Li-Fraumeni Syndrome | 1 | CTD_human;ORPHANET |
| Hgene | TP53 | C0206681 | Adenocarcinoma, Clear Cell | 1 | CTD_human |
| Hgene | TP53 | C0206698 | Cholangiocarcinoma | 1 | CTD_human |
| Hgene | TP53 | C0262584 | Carcinoma, Small Cell | 1 | CTD_human |
| Hgene | TP53 | C0279626 | Squamous cell carcinoma of esophagus | 1 | CTD_human |
| Hgene | TP53 | C0279628 | Adenocarcinoma Of Esophagus | 1 | CTD_human |
| Hgene | TP53 | C0345967 | Malignant mesothelioma | 1 | CTD_human |
| Hgene | TP53 | C0677886 | Epithelial ovarian cancer | 1 | CTD_human |
| Hgene | TP53 | C1168401 | Squamous cell carcinoma of the head and neck | 1 | CTD_human |
| Hgene | TP53 | C1261473 | Sarcoma | 1 | CTD_human;HPO |
| Hgene | TP53 | C1860789 | Leukemia, Megakaryoblastic, of Down Syndrome | 1 | CTD_human |
| Hgene | TP53 | C1961102 | Precursor Cell Lymphoblastic Leukemia Lymphoma | 1 | CTD_human |
| Hgene | TP53 | C2609414 | Acute kidney injury | 1 | CTD_human |
| Hgene | TP53 | C2931713 | Chromosome 17 deletion | 1 | CTD_human |
| Hgene | TP53 | C2931822 | Nasopharyngeal carcinoma | 1 | CTD_human |
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