|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 38913 |
FusionGeneSummary for TNKS_ASAH1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TNKS_ASAH1 | Fusion gene ID: 38913 | Hgene | Tgene | Gene symbol | TNKS | ASAH1 | Gene ID | 8658 | 427 |
| Gene name | tankyrase | N-acylsphingosine amidohydrolase 1 | |
| Synonyms | ARTD5|PARP-5a|PARP5A|PARPL|TIN1|TINF1|TNKS1|pART5 | AC|ACDase|ASAH|PHP|PHP32|SMAPME | |
| Cytomap | 8p23.1 | 8p22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | tankyrase-1ADP-ribosyltransferase diphtheria toxin-like 5TANK1TNKS-1TRF1-interacting ankyrin-related ADP-ribose polymerase 1poly [ADP-ribose] polymerase 5Atankyrase Itankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | acid ceramidaseN-acylsphingosine amidohydrolase (acid ceramidase) 1acid CDaseacylsphingosine deacylaseputative 32 kDa heart protein | |
| Modification date | 20180523 | 20180529 | |
| UniProtAcc | O95271 | Q13510 | |
| Ensembl transtripts involved in fusion gene | ENST00000520408, ENST00000310430, ENST00000518281, ENST00000522110, ENST00000518027, | ENST00000262097, ENST00000381733, ENST00000417108, ENST00000520781, ENST00000314146, ENST00000520051, | |
| Fusion gene scores | * DoF score | 6 X 5 X 6=180 | 6 X 6 X 5=180 |
| # samples | 6 | 7 | |
| ** MAII score | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/180*10)=-1.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TNKS [Title/Abstract] AND ASAH1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TNKS | GO:0000209 | protein polyubiquitination | 19759537|21478859 |
| Hgene | TNKS | GO:0006471 | protein ADP-ribosylation | 9822378|15133513|21270334 |
| Hgene | TNKS | GO:0018105 | peptidyl-serine phosphorylation | 17026964 |
| Hgene | TNKS | GO:0018107 | peptidyl-threonine phosphorylation | 17026964 |
| Hgene | TNKS | GO:0032212 | positive regulation of telomere maintenance via telomerase | 12782650|18221737 |
| Hgene | TNKS | GO:0045944 | positive regulation of transcription by RNA polymerase II | 19245366 |
| Hgene | TNKS | GO:0051973 | positive regulation of telomerase activity | 12782650 |
| Hgene | TNKS | GO:0070212 | protein poly-ADP-ribosylation | 9822378|16076287 |
| Hgene | TNKS | GO:0070213 | protein auto-ADP-ribosylation | 9822378|15133513|19759537|21478859 |
| Hgene | TNKS | GO:1904355 | positive regulation of telomere capping | 21531765 |
| Hgene | TNKS | GO:1904743 | negative regulation of telomeric DNA binding | 9822378 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-D8-A27N-01A | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000520408 | ENST00000262097 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| In-frame | ENST00000520408 | ENST00000381733 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000520408 | ENST00000417108 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000520408 | ENST00000520781 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000520408 | ENST00000314146 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000520408 | ENST00000520051 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| In-frame | ENST00000310430 | ENST00000262097 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| In-frame | ENST00000310430 | ENST00000381733 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000310430 | ENST00000417108 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000310430 | ENST00000520781 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000310430 | ENST00000314146 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000310430 | ENST00000520051 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| In-frame | ENST00000518281 | ENST00000262097 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| In-frame | ENST00000518281 | ENST00000381733 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000518281 | ENST00000417108 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000518281 | ENST00000520781 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000518281 | ENST00000314146 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 5CDS-intron | ENST00000518281 | ENST00000520051 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| intron-3CDS | ENST00000522110 | ENST00000262097 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| intron-3CDS | ENST00000522110 | ENST00000381733 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| intron-intron | ENST00000522110 | ENST00000417108 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| intron-intron | ENST00000522110 | ENST00000520781 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| intron-intron | ENST00000522110 | ENST00000314146 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| intron-intron | ENST00000522110 | ENST00000520051 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 3UTR-3CDS | ENST00000518027 | ENST00000262097 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 3UTR-3CDS | ENST00000518027 | ENST00000381733 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 3UTR-intron | ENST00000518027 | ENST00000417108 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 3UTR-intron | ENST00000518027 | ENST00000520781 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 3UTR-intron | ENST00000518027 | ENST00000314146 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
| 3UTR-intron | ENST00000518027 | ENST00000520051 | TNKS | chr8 | 9473187 | + | ASAH1 | chr8 | 17922040 | - |
Top |
FusionProtFeatures for TNKS_ASAH1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TNKS | ASAH1 |
| Poly-ADP-ribosyltransferase involved in variousprocesses such as Wnt signaling pathway, telomere length andvesicle trafficking. Acts as an activator of the Wnt signalingpathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1and AXIN2, 2 key components of the beta-catenin destructioncomplex: poly-ADP-ribosylated target proteins are recognized byRNF146, which mediates their ubiquitination and subsequentdegradation. Also mediates PARsylation of BLZF1 and CASC3,followed by recruitment of RNF146 and subsequent ubiquitination.Mediates PARsylation of TERF1, thereby contributing to theregulation of telomere length. Involved in centrosome maturationduring prometaphase by mediating PARsylation of HEPACAM2/MIKI. Mayalso regulate vesicle trafficking and modulate the subcellulardistribution of SLC2A4/GLUT4-vesicles. May be involved in spindlepole assembly through PARsylation of NUMA1. Stimulates 26Sproteasome activity. {ECO:0000269|PubMed:10988299,ECO:0000269|PubMed:11739745, ECO:0000269|PubMed:16076287,ECO:0000269|PubMed:19759537, ECO:0000269|PubMed:21478859,ECO:0000269|PubMed:22864114, ECO:0000269|PubMed:23622245}. | Hydrolyzes the sphingolipid ceramide into sphingosineand free fatty acid. {ECO:0000269|PubMed:7744740}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 109_161 | 331 | 1328 | Compositional bias | Ser-rich |
| Hgene | TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 20_83 | 331 | 1328 | Compositional bias | Pro-rich |
| Hgene | TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 9_14 | 331 | 1328 | Compositional bias | Poly-His |
| Hgene | TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 181_209 | 331 | 1328 | Repeat | ANK 1 |
| Hgene | TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 215_244 | 331 | 1328 | Repeat | ANK 2 |
| Hgene | TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 248_277 | 331 | 1328 | Repeat | ANK 3 |
| Hgene | TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 281_310 | 331 | 1328 | Repeat | ANK 4 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 1030_1089 | 331 | 1328 | Domain | SAM |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 1112_1317 | 331 | 1328 | Domain | PARP catalytic |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 335_364 | 331 | 1328 | Repeat | ANK 5 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 368_397 | 331 | 1328 | Repeat | ANK 6 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 401_430 | 331 | 1328 | Repeat | ANK 7 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 434_463 | 331 | 1328 | Repeat | ANK 8 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 521_553 | 331 | 1328 | Repeat | ANK 9 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 557_586 | 331 | 1328 | Repeat | ANK 10 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 590_619 | 331 | 1328 | Repeat | ANK 11 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 621_647 | 331 | 1328 | Repeat | ANK 12 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 649_679 | 331 | 1328 | Repeat | ANK 13 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 683_712 | 331 | 1328 | Repeat | ANK 14 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 716_745 | 331 | 1328 | Repeat | ANK 15 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 749_778 | 331 | 1328 | Repeat | ANK 16 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 782_810 | 331 | 1328 | Repeat | ANK 17 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 836_865 | 331 | 1328 | Repeat | ANK 18 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 869_898 | 331 | 1328 | Repeat | ANK 19 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 902_931 | 331 | 1328 | Repeat | ANK 20 |
| Hgene | >TNKS | chr8:9473187 | chr8:17922040 | ENST00000310430 | + | 3 | 27 | 935_964 | 331 | 1328 | Repeat | ANK 21 |
Top |
FusionGeneSequence for TNKS_ASAH1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TNKS_ENST00000520408_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_600aa MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCC STTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVS GALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLC QGADPNARDNWNTTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEIISFNIFTELFTICTSIVAEDKKGHLI HGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGTVGMLTGFKPGLFSLTLNERFSINGGTLGILEWILGKKDV MWIGFLTRTVLENSTSTEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVTELDAKQGRWTVVQTNTDRWKHPFFLDDRRTP >In-frame_TNKS_ENST00000520408_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_600aa MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCC STTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVS GALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLC QGADPNARDNWNTTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEIISFNIFTELFTICTSIVAEDKKGHLI HGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGTVGMLTGFKPGLFSLTLNERFSINGGTLGILEWILGKKDV MWIGFLTRTVLENSTSTEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVTELDAKQGRWTVVQTNTDRWKHPFFLDDRRTP >In-frame_TNKS_ENST00000310430_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_600aa MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCC STTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVS GALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLC QGADPNARDNWNTTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEIISFNIFTELFTICTSIVAEDKKGHLI HGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGTVGMLTGFKPGLFSLTLNERFSINGGTLGILEWILGKKDV MWIGFLTRTVLENSTSTEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVTELDAKQGRWTVVQTNTDRWKHPFFLDDRRTP >In-frame_TNKS_ENST00000310430_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_600aa MAASRRSQHHHHHHQQQLQPAPGASAPPPPPPPPLSPGLAPGTTPASPTASGLAPFASPRHGLALPEGDGSRDPPDRPRSPDPVDGTSCC STTSTICTVAAAPVVPAVSTSSAAGVAPNPAGSGSNNSPSSSSSPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVS GALRELLEACRNGDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLC QGADPNARDNWNTTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLTGEIISFNIFTELFTICTSIVAEDKKGHLI HGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGTVGMLTGFKPGLFSLTLNERFSINGGTLGILEWILGKKDV MWIGFLTRTVLENSTSTEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLDVTELDAKQGRWTVVQTNTDRWKHPFFLDDRRTP >In-frame_TNKS_ENST00000518281_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_363aa MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNTTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAK AVLTGEIISFNIFTELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGTVGMLTG FKPGLFSLTLNERFSINGGTLGILEWILGKKDVMWIGFLTRTVLENSTSTEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLD VTELDAKQGRWTVVQTNTDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMTDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCI >In-frame_TNKS_ENST00000518281_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_363aa MGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNTTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAK AVLTGEIISFNIFTELFTICTSIVAEDKKGHLIHGRNMDFGVFLGWNINNDTWVITEQLKPLTVNLDFQRNNKTVFKASSFAGTVGMLTG FKPGLFSLTLNERFSINGGTLGILEWILGKKDVMWIGFLTRTVLENSTSTEEAKNLLTKTKILAPAYFILGGNQSGEGCVITRDRKESLD VTELDAKQGRWTVVQTNTDRWKHPFFLDDRRTPAKMCLNRTSQENISFETMTDVLSTKPVLNKLTVYTTLIDVTKGQFETYLRDCPDPCI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TNKS_ENST00000520408_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_1800nt ATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCCCAGGGGCTTCAGCGCCGCCGCCGCCA CCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCGGCCTGGCCCCCTTCGCCTCCCCGCGG CACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGGACCCGGTTGACGGTACCAGCTGTTGC AGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCATCTGCCGCTGGGGTCGCTCCCAACCCA GCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCTCTCCATCCTCCCCTGGATCGAGCTTG GCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGACCTGGGACAGGGGTCCCAGCAGTGAGC GGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGGTGGACGCGGCAAACGTAAATGCAAAG GACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTGTAGAACACTTACTACAGATGGGTGCT AATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTGTTATTGTGC CAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTGTGCATTGTG CTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAAGCTGTCCTT ACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATA CATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACA GTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCA GGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTC ATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTG GCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAA CTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCT GCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAG CTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGA >In-frame_TNKS_ENST00000520408_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_1800nt ATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCCCAGGGGCTTCAGCGCCGCCGCCGCCA CCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCGGCCTGGCCCCCTTCGCCTCCCCGCGG CACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGGACCCGGTTGACGGTACCAGCTGTTGC AGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCATCTGCCGCTGGGGTCGCTCCCAACCCA GCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCTCTCCATCCTCCCCTGGATCGAGCTTG GCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGACCTGGGACAGGGGTCCCAGCAGTGAGC GGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGGTGGACGCGGCAAACGTAAATGCAAAG GACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTGTAGAACACTTACTACAGATGGGTGCT AATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTGTTATTGTGC CAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTGTGCATTGTG CTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAAGCTGTCCTT ACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATA CATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACA GTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCA GGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTC ATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTG GCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAA CTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCT GCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAG CTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGA >In-frame_TNKS_ENST00000310430_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_1800nt ATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCCCAGGGGCTTCAGCGCCGCCGCCGCCA CCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCGGCCTGGCCCCCTTCGCCTCCCCGCGG CACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGGACCCGGTTGACGGTACCAGCTGTTGC AGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCATCTGCCGCTGGGGTCGCTCCCAACCCA GCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCTCTCCATCCTCCCCTGGATCGAGCTTG GCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGACCTGGGACAGGGGTCCCAGCAGTGAGC GGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGGTGGACGCGGCAAACGTAAATGCAAAG GACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTGTAGAACACTTACTACAGATGGGTGCT AATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTGTTATTGTGC CAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTGTGCATTGTG CTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAAGCTGTCCTT ACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATA CATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACA GTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCA GGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTC ATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTG GCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAA CTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCT GCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAG CTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGA >In-frame_TNKS_ENST00000310430_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_1800nt ATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCCCAGGGGCTTCAGCGCCGCCGCCGCCA CCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCGGCCTGGCCCCCTTCGCCTCCCCGCGG CACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGGACCCGGTTGACGGTACCAGCTGTTGC AGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCATCTGCCGCTGGGGTCGCTCCCAACCCA GCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCTCTCCATCCTCCCCTGGATCGAGCTTG GCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGACCTGGGACAGGGGTCCCAGCAGTGAGC GGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGGTGGACGCGGCAAACGTAAATGCAAAG GACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTGTAGAACACTTACTACAGATGGGTGCT AATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTGTTATTGTGC CAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTGTGCATTGTG CTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAAGCTGTCCTT ACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATA CATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACA GTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCA GGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTC ATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTG GCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAA CTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCT GCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAG CTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGA >In-frame_TNKS_ENST00000518281_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_1089nt ATGGGTGCTAATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTG TTATTGTGCCAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTG TGCATTGTGCTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAA GCTGTCCTTACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGT CATCTAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAA CCTTTAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGA TTCAAACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAG AAAGATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACC AAGATATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGAT GTATATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGC AGAACGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTC CTCAACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATA >In-frame_TNKS_ENST00000518281_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_1089nt ATGGGTGCTAATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTG TTATTGTGCCAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTG TGCATTGTGCTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAA GCTGTCCTTACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGT CATCTAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAA CCTTTAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGA TTCAAACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAG AAAGATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACC AAGATATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGAT GTATATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGC AGAACGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTC CTCAACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TNKS_ENST00000520408_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_2935nt AGTGACAGTGCTAGGGGAGTCCGAAGATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCC CAGGGGCTTCAGCGCCGCCGCCGCCACCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCG GCCTGGCCCCCTTCGCCTCCCCGCGGCACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGG ACCCGGTTGACGGTACCAGCTGTTGCAGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCAT CTGCCGCTGGGGTCGCTCCCAACCCAGCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCT CTCCATCCTCCCCTGGATCGAGCTTGGCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGAC CTGGGACAGGGGTCCCAGCAGTGAGCGGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGG TGGACGCGGCAAACGTAAATGCAAAGGACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTG TAGAACACTTACTACAGATGGGTGCTAATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATG CTGAGGTTGTGAGTCTGTTATTGTGCCAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTA AAGGGAAGATCGATGTGTGCATTGTGCTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGG CAGATCCTTCAGCAAAAGCTGTCCTTACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAG CAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCA TAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATG TGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAG AATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGA ATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACA GAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCT TCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCC TGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACT GCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAA CACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATG ACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCAC TGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCG TGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTAT GTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAA TTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGC ACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCC CAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAAT AGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTT AAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCT TTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTG >In-frame_TNKS_ENST00000520408_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_2934nt AGTGACAGTGCTAGGGGAGTCCGAAGATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCC CAGGGGCTTCAGCGCCGCCGCCGCCACCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCG GCCTGGCCCCCTTCGCCTCCCCGCGGCACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGG ACCCGGTTGACGGTACCAGCTGTTGCAGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCAT CTGCCGCTGGGGTCGCTCCCAACCCAGCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCT CTCCATCCTCCCCTGGATCGAGCTTGGCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGAC CTGGGACAGGGGTCCCAGCAGTGAGCGGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGG TGGACGCGGCAAACGTAAATGCAAAGGACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTG TAGAACACTTACTACAGATGGGTGCTAATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATG CTGAGGTTGTGAGTCTGTTATTGTGCCAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTA AAGGGAAGATCGATGTGTGCATTGTGCTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGG CAGATCCTTCAGCAAAAGCTGTCCTTACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAG CAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCA TAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATG TGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAG AATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGA ATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACA GAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCT TCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCC TGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACT GCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAA CACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATG ACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCAC TGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCG TGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTAT GTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAA TTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGC ACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCC CAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAAT AGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTT AAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCT TTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTG >In-frame_TNKS_ENST00000310430_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_2935nt AGTGACAGTGCTAGGGGAGTCCGAAGATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCC CAGGGGCTTCAGCGCCGCCGCCGCCACCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCG GCCTGGCCCCCTTCGCCTCCCCGCGGCACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGG ACCCGGTTGACGGTACCAGCTGTTGCAGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCAT CTGCCGCTGGGGTCGCTCCCAACCCAGCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCT CTCCATCCTCCCCTGGATCGAGCTTGGCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGAC CTGGGACAGGGGTCCCAGCAGTGAGCGGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGG TGGACGCGGCAAACGTAAATGCAAAGGACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTG TAGAACACTTACTACAGATGGGTGCTAATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATG CTGAGGTTGTGAGTCTGTTATTGTGCCAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTA AAGGGAAGATCGATGTGTGCATTGTGCTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGG CAGATCCTTCAGCAAAAGCTGTCCTTACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAG CAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCA TAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATG TGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAG AATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGA ATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACA GAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCT TCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCC TGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACT GCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAA CACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATG ACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCAC TGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCG TGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTAT GTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAA TTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGC ACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCC CAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAAT AGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTT AAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCT TTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTG >In-frame_TNKS_ENST00000310430_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_2934nt AGTGACAGTGCTAGGGGAGTCCGAAGATGGCGGCGTCGCGTCGCTCTCAGCATCATCACCACCATCATCAACAACAGCTCCAGCCCGCCC CAGGGGCTTCAGCGCCGCCGCCGCCACCTCCTCCCCCACTCAGCCCTGGCCTGGCCCCGGGGACCACCCCAGCCTCTCCCACGGCCAGCG GCCTGGCCCCCTTCGCCTCCCCGCGGCACGGCCTAGCGCTGCCGGAGGGGGATGGCAGTCGGGATCCGCCCGACAGGCCCCGATCCCCGG ACCCGGTTGACGGTACCAGCTGTTGCAGTACCACCAGCACAATCTGTACCGTCGCCGCCGCTCCCGTGGTCCCAGCGGTTTCTACTTCAT CTGCCGCTGGGGTCGCTCCCAACCCAGCCGGCAGTGGCAGTAACAATTCACCGTCGTCCTCTTCTTCCCCGACTTCTTCCTCATCTTCCT CTCCATCCTCCCCTGGATCGAGCTTGGCGGAGAGCCCCGAGGCGGCCGGAGTTAGCAGCACAGCACCACTGGGGCCTGGGGCAGCAGGAC CTGGGACAGGGGTCCCAGCAGTGAGCGGGGCCCTACGGGAACTGCTGGAGGCCTGTCGCAATGGGGACGTGTCCCGGGTAAAGAGGCTGG TGGACGCGGCAAACGTAAATGCAAAGGACATGGCCGGCCGGAAGTCTTCTCCCCTGCACTTCGCTGCAGGTTTTGGAAGGAAGGATGTTG TAGAACACTTACTACAGATGGGTGCTAATGTCCACGCTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATG CTGAGGTTGTGAGTCTGTTATTGTGCCAAGGAGCTGATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTA AAGGGAAGATCGATGTGTGCATTGTGCTGCTGCAGCACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGG CAGATCCTTCAGCAAAAGCTGTCCTTACAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAG CAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCA TAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATG TGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAG AATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGA ATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACA GAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCT TCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCC TGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACT GCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAA CACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATG ACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCAC TGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCG TGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTAT GTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAA TTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGC ACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCC CAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAAT AGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTT AAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCT TTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTG >In-frame_TNKS_ENST00000518281_chr8_9473187_+_ASAH1_ENST00000262097_chr8_17922040_-_2629nt AATACCGTTGATAAACTGCTATGTGTGCCTGGATTGCCTTTGTCTTGACAAATTGTGTGAGACAAGTGAATCTCTCCATTATCTTTTTAT TTTCTTTTGACACGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTATAGGGGCGCGATCTCGGCTCATTGCAAGCTCCGCCTCCCGGGTTCA CGCCATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCAGGGCTAATTTTTTGTATATTTAGTAGAGAC GGGTTTCACCATGTTAGCTAGGATGGTCTCGATTTCCTGACCTCGTGATCCGCCTGCTTCGGCCTCCCTAAATTACAGGTGTGAGCCACC GCGCCCGGCGGATAATTTTTTAAGAGGAACAAGGTTTTGGAAGGAAGGATGTTGTAGAACACTTACTACAGATGGGTGCTAATGTCCACG CTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTGTTATTGTGCCAAGGAGCTG ATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTGTGCATTGTGCTGCTGCAGC ACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAAGCTGTCCTTACAGGAGAGA TTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAA ACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGG ATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCA GTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAG GGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCT ACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTA AGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGT GTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTAT ACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCT GGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTC GCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTT TCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGT GGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGG GACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTA ACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAGGGATGAGACAGACAT TCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAG CAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTG CATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTAAATTCTCATAAGTAG CATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTG TATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACTGTGAAATGTACGTCA TTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTGGAAAGAGTGCCAGTC >In-frame_TNKS_ENST00000518281_chr8_9473187_+_ASAH1_ENST00000381733_chr8_17922040_-_2628nt AATACCGTTGATAAACTGCTATGTGTGCCTGGATTGCCTTTGTCTTGACAAATTGTGTGAGACAAGTGAATCTCTCCATTATCTTTTTAT TTTCTTTTGACACGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTATAGGGGCGCGATCTCGGCTCATTGCAAGCTCCGCCTCCCGGGTTCA CGCCATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCAGGGCTAATTTTTTGTATATTTAGTAGAGAC GGGTTTCACCATGTTAGCTAGGATGGTCTCGATTTCCTGACCTCGTGATCCGCCTGCTTCGGCCTCCCTAAATTACAGGTGTGAGCCACC GCGCCCGGCGGATAATTTTTTAAGAGGAACAAGGTTTTGGAAGGAAGGATGTTGTAGAACACTTACTACAGATGGGTGCTAATGTCCACG CTCGTGATGATGGAGGTCTCATCCCGCTTCATAATGCCTGTTCTTTTGGCCATGCTGAGGTTGTGAGTCTGTTATTGTGCCAAGGAGCTG ATCCAAATGCCAGGGATAACTGGAACTATACACCTCTGCATGAAGCTGCTATTAAAGGGAAGATCGATGTGTGCATTGTGCTGCTGCAGC ACGGAGCTGACCCAAACATTCGGAACACTGATGGGAAATCAGCCCTGGACCTGGCAGATCCTTCAGCAAAAGCTGTCCTTACAGGAGAGA TTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAA ACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGG ATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCA GTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAG GGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCT ACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTA AGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGT GTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTAT ACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCT GGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTC GCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTT TCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGT GGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGG GACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTA ACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAGGGATGAGACAGACAT TCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAG CAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTG CATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTAAATTCTCATAAGTAG CATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTG TATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACTGTGAAATGTACGTCA TTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTGGAAAGAGTGCCAGTC |
Top |
FusionGenePPI for TNKS_ASAH1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TNKS | FNBP1, POT1, TERF1, TNKS1BP1, NUMA1, MCL1, TNKS, LNPEP, BABAM1, FANCD2, TERF2, DISC1, SH3BP5, TNIK, GMDS, BLZF1, APC, SH3BP2, TINF2, RNF146, RAPGEF2, RTN2, CEP170, EPN3, SLC35A5, RNF166, PTEN, AXIN1, XPO1, KIF20A, FAM117B, SSSCA1, HIF1AN, SH3BP5L, LRP1, CELF5, MAPK8IP3, KLRG2, TMEM44, CHD1L, AP2M1, TRIM25, HEY1 | ASAH1 | SETDB1, TSC22D1, PSMA3, FBXO6, CAMK1D, SRPK1, GSG1, PNKD, AAGAB, AAMP, NEFH, CAMK2B, HSF2, HSPB2, HERC2, CYP1A2, GLT1D1, ZIC1, ZSCAN12, FTH1, NONO, TBC1D22B, SLCO6A1, AIRE, HTATIP2, RNF6, TRMT2A, ZNF684, ZNF556, HMP19, LYPD1, NCDN |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for TNKS_ASAH1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for TNKS_ASAH1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ASAH1 | C0268255 | Farber Lipogranulomatosis | 8 | CTD_human;ORPHANET;UNIPROT |
| Tgene | ASAH1 | C0023794 | Lipoidosis | 2 | CTD_human |
| Tgene | ASAH1 | C1834569 | Jankovic Rivera syndrome | 2 | ORPHANET;UNIPROT |
| Tgene | ASAH1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | ASAH1 | C0036341 | Schizophrenia | 1 | PSYGENET |
| Tgene | ASAH1 | C0221765 | Chronic schizophrenia | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|