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Fusion gene ID: 38793 |
FusionGeneSummary for TMTC1_PGD |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TMTC1_PGD | Fusion gene ID: 38793 | Hgene | Tgene | Gene symbol | TMTC1 | PGD | Gene ID | 83857 | 26227 |
| Gene name | transmembrane and tetratricopeptide repeat containing 1 | phosphoglycerate dehydrogenase | |
| Synonyms | ARG99|OLF|TMTC1A | 3-PGDH|3PGDH|HEL-S-113|NLS|NLS1|PDG|PGAD|PGD|PGDH|PHGDHD|SERA | |
| Cytomap | 12p11.22 | 1p12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transmembrane and TPR repeat-containing protein 1transmembrane and tetratricopeptide repeat containing 1A | D-3-phosphoglycerate dehydrogenase2-oxoglutarate reductase3-phosphoglycerate dehydrogenaseepididymis secretory protein Li 113malate dehydrogenase | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8IUR5 | P52209 | |
| Ensembl transtripts involved in fusion gene | ENST00000256062, ENST00000551659, ENST00000552618, ENST00000319685, ENST00000539277, ENST00000381224, | ENST00000541529, ENST00000270776, ENST00000538557, ENST00000498356, | |
| Fusion gene scores | * DoF score | 7 X 6 X 5=210 | 5 X 4 X 5=100 |
| # samples | 7 | 5 | |
| ** MAII score | log2(7/210*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TMTC1 [Title/Abstract] AND PGD [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | UCEC | TCGA-D1-A3JQ-01A | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000256062 | ENST00000541529 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| Frame-shift | ENST00000256062 | ENST00000270776 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-5UTR | ENST00000256062 | ENST00000538557 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-intron | ENST00000256062 | ENST00000498356 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| In-frame | ENST00000551659 | ENST00000541529 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| In-frame | ENST00000551659 | ENST00000270776 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-5UTR | ENST00000551659 | ENST00000538557 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-intron | ENST00000551659 | ENST00000498356 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| In-frame | ENST00000552618 | ENST00000541529 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| In-frame | ENST00000552618 | ENST00000270776 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-5UTR | ENST00000552618 | ENST00000538557 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-intron | ENST00000552618 | ENST00000498356 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| intron-3CDS | ENST00000319685 | ENST00000541529 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| intron-3CDS | ENST00000319685 | ENST00000270776 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| intron-5UTR | ENST00000319685 | ENST00000538557 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| intron-intron | ENST00000319685 | ENST00000498356 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| In-frame | ENST00000539277 | ENST00000541529 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| In-frame | ENST00000539277 | ENST00000270776 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-5UTR | ENST00000539277 | ENST00000538557 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-intron | ENST00000539277 | ENST00000498356 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| Frame-shift | ENST00000381224 | ENST00000541529 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| Frame-shift | ENST00000381224 | ENST00000270776 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-5UTR | ENST00000381224 | ENST00000538557 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
| 5CDS-intron | ENST00000381224 | ENST00000498356 | TMTC1 | chr12 | 29904599 | - | PGD | chr1 | 10459686 | + |
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FusionProtFeatures for TMTC1_PGD |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TMTC1 | PGD |
| Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), withconcomitant reduction of NADP to NADPH. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for TMTC1_PGD |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TMTC1_ENST00000551659_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_772aa MVVTTSARGGGGDRTPSRRRGCGLAPAGAAALLAGASCLCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWGIFTNDFWGKGMAENTSHK SYRPLCVLTFKLNIFLTGMNPFYFHAVNIILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAF LSYNRSLDQGCVGGSFPSTVSPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSLSNKQDKSSNGALCPRSPQQPGSPQPSSLPGHPH RENGKQQRFPHKGAWGGCHSPLPPEPKSSGFPVSPRAVWSMMRADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGT KVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAA KVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLP KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLL RQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDG >In-frame_TMTC1_ENST00000551659_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_794aa MVVTTSARGGGGDRTPSRRRGCGLAPAGAAALLAGASCLCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWGIFTNDFWGKGMAENTSHK SYRPLCVLTFKLNIFLTGMNPFYFHAVNIILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAF LSYNRSLDQGCVGGSFPSTVSPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSLSNKQDKSSNGALCPRSPQQPGSPQPSSLPGHPH RENGKQQRFPHKGAWGGCHSPLPPEPKSSGFPVSPRAVWSMMRADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGT KVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPS LMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDS FLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFL EDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAV >In-frame_TMTC1_ENST00000552618_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_772aa MVVTTSARGGGGDRTPSRRRGCGLAPAGAAALLAGASCLCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWGIFTNDFWGKGMAENTSHK SYRPLCVLTFKLNIFLTGMNPFYFHAVNIILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAF LSYNRSLDQGCVGGSFPSTVSPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSLSNKQDKSSNGALCPRSPQQPGSPQPSSLPGHPH RENGKQQRFPHKGAWGGCHSPLPPEPKSSGFPVSPRAVWSMMRADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGT KVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAA KVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLP KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLL RQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDG >In-frame_TMTC1_ENST00000552618_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_794aa MVVTTSARGGGGDRTPSRRRGCGLAPAGAAALLAGASCLCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWGIFTNDFWGKGMAENTSHK SYRPLCVLTFKLNIFLTGMNPFYFHAVNIILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAF LSYNRSLDQGCVGGSFPSTVSPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSLSNKQDKSSNGALCPRSPQQPGSPQPSSLPGHPH RENGKQQRFPHKGAWGGCHSPLPPEPKSSGFPVSPRAVWSMMRADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGT KVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPS LMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDS FLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFL EDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAV >In-frame_TMTC1_ENST00000539277_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_772aa MVVTTSARGGGGDRTPSRRRGCGLAPAGAAALLAGASCLCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWGIFTNDFWGKGMAENTSHK SYRPLCVLTFKLNIFLTGMNPFYFHAVNIILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAF LSYNRSLDQGCVGGSFPSTVSPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSLSNKQDKSSNGALCPRSPQQPGSPQPSSLPGHPH RENGKQQRFPHKGAWGGCHSPLPPEPKSSGFPVSPRAVWSMMRADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGT KVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAA KVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLP KIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLL RQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDG >In-frame_TMTC1_ENST00000539277_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_794aa MVVTTSARGGGGDRTPSRRRGCGLAPAGAAALLAGASCLCYGRSLQGEFVHDDVWAIVNNPDVRPGAPLRWGIFTNDFWGKGMAENTSHK SYRPLCVLTFKLNIFLTGMNPFYFHAVNIILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPIHTEAVAGIVGRADVLACLLFLLAF LSYNRSLDQGCVGGSFPSTVSPFFLLLSLFLGTCAMLVKETGITVFGVCLVYDLFSLSNKQDKSSNGALCPRSPQQPGSPQPSSLPGHPH RENGKQQRFPHKGAWGGCHSPLPPEPKSSGFPVSPRAVWSMMRADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGT KVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPS LMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDS FLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKLKGPQKFQFDGDKKSFL EDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TMTC1_ENST00000551659_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_2316nt ATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCG GCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAAC CCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAG TCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATT TTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTT TTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTT CTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTT CTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAG CAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCAC CGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGA TTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTG AACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACC AAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCT GTGGATGATTTCATCGAGAAATTGAGACGGTGCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAG GAAGGGGCCCGGTATGGCCCATCGCTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCA AAAGTGGGAACTGGAGAACCCTGCTGTGACTGGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTAT GGGGACATGCAGCTGATCTGTGAGGCATACCACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGAT TGGAATAAGACAGAGCTAGACTCATTCCTGATTGAAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCA AAGATCAGGGACAGCGCGGGGCAGAAGGGCACAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGA GAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTT GATGGTGATAAGAAATCATTCCTGGAGGACATTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTA AGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTC CTAGGAAAGATAAAGGATGCATTTGATCGAAACCCGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGC CAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGG TACAGACATGAGATGCTTCCAGCCAGCCTCATCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGG >In-frame_TMTC1_ENST00000551659_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_2382nt ATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCG GCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAAC CCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAG TCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATT TTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTT TTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTT CTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTT CTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAG CAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCAC CGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGA TTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTG AACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACC AAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCT GTGGATGATTTCATCGAGAAATTGGTACCATTGTTGGATACTGGTGACATCATCATTGACGGAGGAAATTCTGAATATAGGGACACCACA AGACGGTGCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCG CTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGC TGTGACTGGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAG GCATACCACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCA TTCCTGATTGAAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAG AAGGGCACAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTA TCATCTCTGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTG GAGGACATTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGC TGGACTCTCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTT GATCGAAACCCGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTC AGCACTGGGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCC AGCCTCATCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACA >In-frame_TMTC1_ENST00000552618_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_2316nt ATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCG GCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAAC CCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAG TCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATT TTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTT TTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTT CTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTT CTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAG CAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCAC CGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGA TTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTG AACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACC AAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCT GTGGATGATTTCATCGAGAAATTGAGACGGTGCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAG GAAGGGGCCCGGTATGGCCCATCGCTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCA AAAGTGGGAACTGGAGAACCCTGCTGTGACTGGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTAT GGGGACATGCAGCTGATCTGTGAGGCATACCACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGAT TGGAATAAGACAGAGCTAGACTCATTCCTGATTGAAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCA AAGATCAGGGACAGCGCGGGGCAGAAGGGCACAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGA GAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTT GATGGTGATAAGAAATCATTCCTGGAGGACATTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTA AGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTC CTAGGAAAGATAAAGGATGCATTTGATCGAAACCCGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGC CAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGG TACAGACATGAGATGCTTCCAGCCAGCCTCATCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGG >In-frame_TMTC1_ENST00000552618_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_2382nt ATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCG GCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAAC CCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAG TCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATT TTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTT TTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTT CTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTT CTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAG CAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCAC CGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGA TTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTG AACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACC AAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCT GTGGATGATTTCATCGAGAAATTGGTACCATTGTTGGATACTGGTGACATCATCATTGACGGAGGAAATTCTGAATATAGGGACACCACA AGACGGTGCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCG CTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGC TGTGACTGGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAG GCATACCACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCA TTCCTGATTGAAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAG AAGGGCACAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTA TCATCTCTGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTG GAGGACATTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGC TGGACTCTCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTT GATCGAAACCCGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTC AGCACTGGGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCC AGCCTCATCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACA >In-frame_TMTC1_ENST00000539277_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_2316nt ATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCG GCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAAC CCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAG TCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATT TTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTT TTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTT CTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTT CTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAG CAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCAC CGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGA TTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTG AACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACC AAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCT GTGGATGATTTCATCGAGAAATTGAGACGGTGCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAG GAAGGGGCCCGGTATGGCCCATCGCTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCA AAAGTGGGAACTGGAGAACCCTGCTGTGACTGGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTAT GGGGACATGCAGCTGATCTGTGAGGCATACCACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGAT TGGAATAAGACAGAGCTAGACTCATTCCTGATTGAAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCA AAGATCAGGGACAGCGCGGGGCAGAAGGGCACAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGA GAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTT GATGGTGATAAGAAATCATTCCTGGAGGACATTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTA AGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTC CTAGGAAAGATAAAGGATGCATTTGATCGAAACCCGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGC CAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGG TACAGACATGAGATGCTTCCAGCCAGCCTCATCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGG >In-frame_TMTC1_ENST00000539277_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_2382nt ATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCG GCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAAC CCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAG TCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATT TTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTT TTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTT CTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTT CTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAG CAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCAC CGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGA TTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTG AACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACC AAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCT GTGGATGATTTCATCGAGAAATTGGTACCATTGTTGGATACTGGTGACATCATCATTGACGGAGGAAATTCTGAATATAGGGACACCACA AGACGGTGCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCG CTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGC TGTGACTGGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAG GCATACCACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCA TTCCTGATTGAAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAG AAGGGCACAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTA TCATCTCTGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTG GAGGACATTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGC TGGACTCTCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTT GATCGAAACCCGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTC AGCACTGGGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCC AGCCTCATCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TMTC1_ENST00000551659_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_2501nt GCGCGGGGAGCTCGCGGCGGGTCCAGCTGCCGCAGCACCATGCCCGAGCCCCCCTCCGGGCAGACGCCGCGCGCCGCCGGGGCCCCGGTA GGGGAGGATGCCAGACGCCCGGGAGAGGCCAGGGCAGCAGCGGCGGCGGCGGCGCGATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCG GGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCGGCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACG GCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAACCCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGG GCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAGTCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGC TAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATTTTACACTGCTTAGTGACTCTTGTGCTGATGTACA CCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTTTTTGCTGTACATCCTATTCATACTGAGGCGGTGG CTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTTCTCTCGTACAACAGGAGTCTGGATCAGGGCTGTG TTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTTCTGGGGACCTGTGCGATGCTGGTGAAAGAGACAG GCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAGCAAGACAAGTCGAGCAATGGGGCCCTCTGTCCAC GCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCACCGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACA AAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGATTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGA TGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTGAACATGAATGACCACGGCTTTGTGGTCTGTGCTT TTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACCAAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGG TCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCTGTGGATGATTTCATCGAGAAATTGAGACGGTGCC GAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCGCTCATGCCAG GAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGCTGTGACTGGG TGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAGGCATACCACC TGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCATTCCTGATTG AAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAGAAGGGCACAG GGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGA AGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTGGAGGACATTC GGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCA ATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTTGATCGAAACC CGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGG TCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCCAGCCTCATCC AGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACAGGCCATGGTG >In-frame_TMTC1_ENST00000551659_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_2923nt GCGCGGGGAGCTCGCGGCGGGTCCAGCTGCCGCAGCACCATGCCCGAGCCCCCCTCCGGGCAGACGCCGCGCGCCGCCGGGGCCCCGGTA GGGGAGGATGCCAGACGCCCGGGAGAGGCCAGGGCAGCAGCGGCGGCGGCGGCGCGATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCG GGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCGGCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACG GCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAACCCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGG GCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAGTCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGC TAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATTTTACACTGCTTAGTGACTCTTGTGCTGATGTACA CCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTTTTTGCTGTACATCCTATTCATACTGAGGCGGTGG CTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTTCTCTCGTACAACAGGAGTCTGGATCAGGGCTGTG TTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTTCTGGGGACCTGTGCGATGCTGGTGAAAGAGACAG GCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAGCAAGACAAGTCGAGCAATGGGGCCCTCTGTCCAC GCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCACCGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACA AAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGATTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGA TGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTGAACATGAATGACCACGGCTTTGTGGTCTGTGCTT TTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACCAAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGG TCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCTGTGGATGATTTCATCGAGAAATTGGTACCATTGT TGGATACTGGTGACATCATCATTGACGGAGGAAATTCTGAATATAGGGACACCACAAGACGGTGCCGAGACCTCAAGGCCAAGGGAATTT TATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCGCTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCC ACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGCTGTGACTGGGTGGGAGATGAGGGAGCAGGCCACT TCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAGGCATACCACCTGATGAAAGACGTGCTGGGCATGG CGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCATTCCTGATTGAAATCACAGCCAATATTCTCAAGT TCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAGAAGGGCACAGGGAAGTGGACCGCCATCTCCGCCC TGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGAAGGATGAGAGAATTCAAGCTAGCA AAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTGGAGGACATTCGGAAGGCACTCTACGCTTCCAAGA TCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCAATTATGGTGGCATCGCCCTGATGT GGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTTGATCGAAACCCGGAACTTCAGAACCTCCTACTGG ACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGGTCCAGGCTGGCATTCCCATGCCCT GTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCCAGCCTCATCCAGGCTCAGCGGGATTACTTCGGGG CTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACAGGCCATGGTGGCACCGTGTCATCCTCGTCATACA ATGCCTGATCATGCTGCTCCTGTCACCCTCCACGATTCCACAGACCAGGACATTCCATGTGCCTCATGGCACTGCCACCTGGCCCTTTGC CCTATTTTCTGTTCAGTTTTTTAAAAGTGTTGTAAGAGACTCCTGAGGAAGACACACAGTTTATTTGTAAAGTAGCTCTGTGAGAGCCAC CATGCCCTCTGCCCTTGCCTCTTGGGACTGACCAGGAGCTGCTCATGTGCGTGAGAGTGGGAACCATCTCCTTGCGGCAGTGGCTTCCGC GTGCCCCGTGTGCTGGTGCGGTTCCCATCACGCAGACAGGAAGGGTGTTTGCGCACTCTGATCAACTGGAACCTCTGTATCATGCGGCTG >In-frame_TMTC1_ENST00000552618_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_2402nt GCCAGACGCCCGGGAGAGGCCAGGGCAGCAGCGGCGGCGGCGGCGCGATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCA CACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCGGCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCC TGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAACCCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCA CCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAGTCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATAT TTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATTTTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATA AAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTTTTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCG TTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTTCTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAA GTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTTCTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGG TGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAGCAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCAC AGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCACCGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTT GGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGATTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTG ACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTGAACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGA CTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACCAAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGC TGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCTGTGGATGATTTCATCGAGAAATTGAGACGGTGCCGAGACCTCA AGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCGCTCATGCCAGGAGGGAACA AAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGCTGTGACTGGGTGGGAGATG AGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAGGCATACCACCTGATGAAAG ACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCATTCCTGATTGAAATCACAG CCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAGAAGGGCACAGGGAAGTGGA CCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGAAGGATGAGA GAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTGGAGGACATTCGGAAGGCAC TCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCAATTATGGTG GCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTTGATCGAAACCCGGAACTTC AGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGGTCCAGGCTG GCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCCAGCCTCATCCAGGCTCAGC GGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACAGGCCATGGTGGCACCGTGT >In-frame_TMTC1_ENST00000552618_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_2824nt GCCAGACGCCCGGGAGAGGCCAGGGCAGCAGCGGCGGCGGCGGCGCGATGGTGGTGACCACCTCTGCCCGAGGCGGCGGCGGGGACCGCA CACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCGGCGCTGCTGGCCGGGGCAAGCTGCCTGTGCTACGGCCGCTCCC TGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAACCCCGACGTGCGGCCCGGCGCCCCGCTCCGCTGGGGCATCTTCA CCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAGTCCTACCGGCCGCTCTGCGTCCTCACCTTCAAGCTAAACATAT TTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATTTTACACTGCTTAGTGACTCTTGTGCTGATGTACACCTGTGATA AAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTTTTTGCTGTACATCCTATTCATACTGAGGCGGTGGCTGGGATCG TTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTTCTCTCGTACAACAGGAGTCTGGATCAGGGCTGTGTTGGGGGAA GTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTTCTGGGGACCTGTGCGATGCTGGTGAAAGAGACAGGCATCACGG TGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAGCAAGACAAGTCGAGCAATGGGGCCCTCTGTCCACGCAGCCCAC AGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCACCGGGAGAATGGGAAGCAGCAGCGGTTCCCTCACAAAGGAGCTT GGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGATTCCCAGTGTCCCCACGAGCTGTGTGGTCCATGATGAGAGCTG ACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTGAACATGAATGACCACGGCTTTGTGGTCTGTGCTTTTAATAGGA CTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACCAAAGTGGTGGGTGCCCAGTCCCTGAAAGAGATGGTCTCCAAGC TGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCTGTGGATGATTTCATCGAGAAATTGGTACCATTGTTGGATACTG GTGACATCATCATTGACGGAGGAAATTCTGAATATAGGGACACCACAAGACGGTGCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGG GGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCGCTCATGCCAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGA CCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGCTGTGACTGGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGA TGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAGGCATACCACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACG AGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCATTCCTGATTGAAATCACAGCCAATATTCTCAAGTTCCAAGACA CCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAGAAGGGCACAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACG GCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGA AGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTGGAGGACATTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTT ACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGG GCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTTGATCGAAACCCGGAACTTCAGAACCTCCTACTGGACGACTTCT TTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCA CTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCCAGCCTCATCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCT ATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACAGGCCATGGTGGCACCGTGTCATCCTCGTCATACAATGCCTGAT CATGCTGCTCCTGTCACCCTCCACGATTCCACAGACCAGGACATTCCATGTGCCTCATGGCACTGCCACCTGGCCCTTTGCCCTATTTTC TGTTCAGTTTTTTAAAAGTGTTGTAAGAGACTCCTGAGGAAGACACACAGTTTATTTGTAAAGTAGCTCTGTGAGAGCCACCATGCCCTC TGCCCTTGCCTCTTGGGACTGACCAGGAGCTGCTCATGTGCGTGAGAGTGGGAACCATCTCCTTGCGGCAGTGGCTTCCGCGTGCCCCGT GTGCTGGTGCGGTTCCCATCACGCAGACAGGAAGGGTGTTTGCGCACTCTGATCAACTGGAACCTCTGTATCATGCGGCTGAATTCCCTT >In-frame_TMTC1_ENST00000539277_chr12_29904599_-_PGD_ENST00000541529_chr1_10459686_+_2414nt GTAGGGGAGGATGCCAGACGCCCGGGAGAGGCCAGGGCAGCAGCGGCGGCGGCGGCGCGATGGTGGTGACCACCTCTGCCCGAGGCGGCG GCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCGGCGCTGCTGGCCGGGGCAAGCTGCCTGTGCT ACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAACCCCGACGTGCGGCCCGGCGCCCCGCTCCGCT GGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAGTCCTACCGGCCGCTCTGCGTCCTCACCTTCA AGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATTTTACACTGCTTAGTGACTCTTGTGCTGATGT ACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTTTTTGCTGTACATCCTATTCATACTGAGGCGG TGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTTCTCTCGTACAACAGGAGTCTGGATCAGGGCT GTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTTCTGGGGACCTGTGCGATGCTGGTGAAAGAGA CAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAGCAAGACAAGTCGAGCAATGGGGCCCTCTGTC CACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCACCGGGAGAATGGGAAGCAGCAGCGGTTCCCTC ACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGATTCCCAGTGTCCCCACGAGCTGTGTGGTCCA TGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTGAACATGAATGACCACGGCTTTGTGGTCTGTG CTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACCAAAGTGGTGGGTGCCCAGTCCCTGAAAGAGA TGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCTGTGGATGATTTCATCGAGAAATTGAGACGGT GCCGAGACCTCAAGGCCAAGGGAATTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCGCTCATGC CAGGAGGGAACAAAGAAGCGTGGCCCCACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGCTGTGACT GGGTGGGAGATGAGGGAGCAGGCCACTTCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAGGCATACC ACCTGATGAAAGACGTGCTGGGCATGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCATTCCTGA TTGAAATCACAGCCAATATTCTCAAGTTCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAGAAGGGCA CAGGGAAGTGGACCGCCATCTCCGCCCTGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTATCATCTC TGAAGGATGAGAGAATTCAAGCTAGCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTGGAGGACA TTCGGAAGGCACTCTACGCTTCCAAGATCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGCTGGACTC TCAATTATGGTGGCATCGCCCTGATGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTTGATCGAA ACCCGGAACTTCAGAACCTCCTACTGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTCAGCACTG GGGTCCAGGCTGGCATTCCCATGCCCTGTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCCAGCCTCA TCCAGGCTCAGCGGGATTACTTCGGGGCTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACAGGCCATG >In-frame_TMTC1_ENST00000539277_chr12_29904599_-_PGD_ENST00000270776_chr1_10459686_+_2836nt GTAGGGGAGGATGCCAGACGCCCGGGAGAGGCCAGGGCAGCAGCGGCGGCGGCGGCGCGATGGTGGTGACCACCTCTGCCCGAGGCGGCG GCGGGGACCGCACACCCTCCCGGCGGCGGGGCTGCGGGCTAGCGCCGGCCGGGGCCGCGGCGCTGCTGGCCGGGGCAAGCTGCCTGTGCT ACGGCCGCTCCCTGCAGGGCGAGTTCGTGCACGACGACGTGTGGGCGATCGTGAACAACCCCGACGTGCGGCCCGGCGCCCCGCTCCGCT GGGGCATCTTCACCAACGACTTCTGGGGCAAGGGCATGGCCGAGAACACCAGCCACAAGTCCTACCGGCCGCTCTGCGTCCTCACCTTCA AGCTAAACATATTTTTGACTGGTATGAACCCATTCTACTTTCATGCAGTAAATATAATTTTACACTGCTTAGTGACTCTTGTGCTGATGT ACACCTGTGATAAAACTGTCTTCAAGAATCGTGGACTTGCTTTTGTAACGGCATTGCTTTTTGCTGTACATCCTATTCATACTGAGGCGG TGGCTGGGATCGTTGGCAGAGCGGACGTGTTAGCGTGTCTGCTGTTTCTATTGGCCTTTCTCTCGTACAACAGGAGTCTGGATCAGGGCT GTGTTGGGGGAAGTTTCCCTTCCACGGTGTCTCCCTTCTTCTTGCTGCTCAGTTTGTTTCTGGGGACCTGTGCGATGCTGGTGAAAGAGA CAGGCATCACGGTGTTTGGAGTGTGCTTGGTTTATGACCTCTTTTCCCTTTCCAACAAGCAAGACAAGTCGAGCAATGGGGCCCTCTGTC CACGCAGCCCACAGCAGCCCGGGAGCCCCCAGCCCTCCTCACTGCCAGGCCATCCTCACCGGGAGAATGGGAAGCAGCAGCGGTTCCCTC ACAAAGGAGCTTGGGGTGGCTGCCACTCTCCACTGCCACCAGAACCCAAGAGCAGTGGATTCCCAGTGTCCCCACGAGCTGTGTGGTCCA TGATGAGAGCTGACATCGCGCTGATCGGATTGGCCGTCATGGGCCAGAACTTAATTCTGAACATGAATGACCACGGCTTTGTGGTCTGTG CTTTTAATAGGACTGTCTCCAAAGTTGATGATTTCTTGGCCAATGAGGCAAAGGGAACCAAAGTGGTGGGTGCCCAGTCCCTGAAAGAGA TGGTCTCCAAGCTGAAGAAGCCCCGGCGGATCATCCTCCTGGTGAAGGCTGGGCAAGCTGTGGATGATTTCATCGAGAAATTGGTACCAT TGTTGGATACTGGTGACATCATCATTGACGGAGGAAATTCTGAATATAGGGACACCACAAGACGGTGCCGAGACCTCAAGGCCAAGGGAA TTTTATTTGTGGGGAGCGGAGTCAGTGGTGGAGAGGAAGGGGCCCGGTATGGCCCATCGCTCATGCCAGGAGGGAACAAAGAAGCGTGGC CCCACATCAAGACCATCTTCCAAGGCATTGCTGCAAAAGTGGGAACTGGAGAACCCTGCTGTGACTGGGTGGGAGATGAGGGAGCAGGCC ACTTCGTGAAGATGGTGCACAACGGGATAGAGTATGGGGACATGCAGCTGATCTGTGAGGCATACCACCTGATGAAAGACGTGCTGGGCA TGGCGCAGGACGAGATGGCCCAGGCCTTTGAGGATTGGAATAAGACAGAGCTAGACTCATTCCTGATTGAAATCACAGCCAATATTCTCA AGTTCCAAGACACCGATGGCAAACACCTGCTGCCAAAGATCAGGGACAGCGCGGGGCAGAAGGGCACAGGGAAGTGGACCGCCATCTCCG CCCTGGAATACGGCGTACCCGTCACCCTCATTGGAGAAGCTGTCTTTGCTCGGTGCTTATCATCTCTGAAGGATGAGAGAATTCAAGCTA GCAAAAAGCTGAAGGGTCCCCAGAAGTTCCAGTTTGATGGTGATAAGAAATCATTCCTGGAGGACATTCGGAAGGCACTCTACGCTTCCA AGATCATCTCTTACGCTCAAGGCTTTATGCTGCTAAGGCAGGCAGCCACCGAGTTTGGCTGGACTCTCAATTATGGTGGCATCGCCCTGA TGTGGAGAGGGGGCTGCATCATTAGAAGTGTATTCCTAGGAAAGATAAAGGATGCATTTGATCGAAACCCGGAACTTCAGAACCTCCTAC TGGACGACTTCTTTAAGTCAGCTGTTGAAAACTGCCAGGACTCCTGGCGGCGGGCAGTCAGCACTGGGGTCCAGGCTGGCATTCCCATGC CCTGTTTTACCACTGCCCTCTCCTTCTATGACGGGTACAGACATGAGATGCTTCCAGCCAGCCTCATCCAGGCTCAGCGGGATTACTTCG GGGCTCACACCTATGAACTCTTGGCCAAACCAGGGCAGTTTATCCACACCAACTGGACAGGCCATGGTGGCACCGTGTCATCCTCGTCAT ACAATGCCTGATCATGCTGCTCCTGTCACCCTCCACGATTCCACAGACCAGGACATTCCATGTGCCTCATGGCACTGCCACCTGGCCCTT TGCCCTATTTTCTGTTCAGTTTTTTAAAAGTGTTGTAAGAGACTCCTGAGGAAGACACACAGTTTATTTGTAAAGTAGCTCTGTGAGAGC CACCATGCCCTCTGCCCTTGCCTCTTGGGACTGACCAGGAGCTGCTCATGTGCGTGAGAGTGGGAACCATCTCCTTGCGGCAGTGGCTTC CGCGTGCCCCGTGTGCTGGTGCGGTTCCCATCACGCAGACAGGAAGGGTGTTTGCGCACTCTGATCAACTGGAACCTCTGTATCATGCGG |
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FusionGenePPI for TMTC1_PGD |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TMTC1 | ZDHHC17, DPPA4, BCOR | PGD | LSM8, USPL1, ISG15, TERF1, CDK2, IQCB1, CDK4, ALDH7A1, ALDH9A1, EEF2, GLA, GNAI3, HMGB2, AHSA1, C12orf10, CHORDC1, EIF4H, G6PD, LDHA, LDHB, NDRG1, PDIA3, SORD, TCEA1, TGM2, THOP1, YWHAB, YWHAG, YWHAQ, RPS6KA1, TXNDC5, WWOX, MOV10, NXF1, FABP5, GDI1, P4HB, ACAA2, CDV3, CTSL, EZR, ISYNA1, MSN, NCBP1, RDX, SUMO2, TAGLN, UCHL3, SUMO3, TALDO1, CEP290, OFD1, RBM8A, CDC73, BRCA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TMTC1_PGD |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | PGD | P52209 | DB00920 | Ketotifen | 6-phosphogluconate dehydrogenase, decarboxylating | small molecule | approved |
| Tgene | PGD | P52209 | DB00851 | Dacarbazine | 6-phosphogluconate dehydrogenase, decarboxylating | small molecule | approved|investigational |
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RelatedDiseases for TMTC1_PGD |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PGD | C2239176 | Liver carcinoma | 1 | CTD_human |
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