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Fusion gene ID: 38500 |
FusionGeneSummary for TMEM180_GBF1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TMEM180_GBF1 | Fusion gene ID: 38500 | Hgene | Tgene | Gene symbol | TMEM180 | GBF1 | Gene ID | 80142 |
| Gene name | prostaglandin E synthase 2 | ||
| Synonyms | C9orf15|GBF-1|GBF1|PGES2|mPGES-2 | ||
| Cytomap | 9q34.11 | ||
| Type of gene | protein-coding | ||
| Description | prostaglandin E synthase 2GATE-binding factor 1gamma-interferon-activated transcriptional element-binding factor 1mPGE synthase-2membrane-associated prostaglandin E synthase 2microsomal prostaglandin E synthase-2prostaglandin-H(2) E-isomerase | ||
| Modification date | 20180519 | ||
| UniProtAcc | Q92538 | ||
| Ensembl transtripts involved in fusion gene | ENST00000366277, ENST00000238936, ENST00000369931, ENST00000450947, | ENST00000369983, ENST00000476019, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 9 X 8 X 5=360 |
| # samples | 1 | 12 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(12/360*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TMEM180 [Title/Abstract] AND GBF1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | STAD | TCGA-VQ-A91K-01A | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000366277 | ENST00000369983 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| 5CDS-intron | ENST00000366277 | ENST00000476019 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| In-frame | ENST00000238936 | ENST00000369983 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| 5CDS-intron | ENST00000238936 | ENST00000476019 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| intron-3CDS | ENST00000369931 | ENST00000369983 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| intron-intron | ENST00000369931 | ENST00000476019 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| intron-3CDS | ENST00000450947 | ENST00000369983 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
| intron-intron | ENST00000450947 | ENST00000476019 | TMEM180 | chr10 | 104233769 | + | GBF1 | chr10 | 104111013 | + |
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FusionProtFeatures for TMEM180_GBF1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TMEM180 | GBF1 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | Guanine-nucleotide exchange factor (GEF) for members ofthe Arf family of small GTPases involved in trafficking in theearly secretory pathway; its GEF activity initiates the coating ofnascent vesicles via the localized generation of activated ARFsthrough replacement of GDP with GTP. Recruitment to cis-Golgimembranes requires membrane association of Arf-GDP and can beregulated by ARF1, ARF3, ARF4 and ARF5. Involved in therecruitment of the COPI coat complex to the endoplasmic reticulumexit sites (ERES), and the endoplasmic reticulum-Golgiintermediate (ERGIC) and cis-Golgi compartments which implicatesARF1 activation. Involved in COPI vesicle-dependent retrogradetransport from the ERGIC and cis-Golgi compartments to theendoplasmic reticulum (ER) (PubMed:16926190, PubMed:17956946,PubMed:18003980, PubMed:12047556, PubMed:12808027,PubMed:19039328, PubMed:24213530). Involved in the trans-Golginetwork recruitment of GGA1, GGA2, GGA3, BIG1, BIG2, and the AP-1adaptor protein complex related to chlathrin-dependent transport;the function requires its GEF activity (probably at least in parton ARF4 and ARF5) (PubMed:23386609). Has GEF activity towards ARF1(PubMed:15616190). Has in vitro GEF activity towards ARF5 (Bysimilarity). Involved in the processing of PSAP (PubMed:17666033).Required for the assembly of the Golgi apparatus (PubMed:12808027,PubMed:18003980). The AMPK-phosphorylated form is involved inGolgi disassembly during mitotis and under stress conditions(PubMed:18063581, PubMed:23418352). May be involved in the COPIvesicle-dependent recruitment of PNPLA2 to lipid droplets;however, this function is under debate (PubMed:19461073,PubMed:22185782). In neutrophils, involved in G protein-coupledreceptor (GPCR)-mediated chemotaxis und superoxide production.Proposed to be recruited by phosphatidylinositol-phosphatesgenerated upon GPCR stimulation to the leading edge where itrecruits and activates ARF1, and is involved in recruitment ofGIT2 and the NADPH oxidase complex (PubMed:22573891).{ECO:0000250|UniProtKB:Q9R1D7, ECO:0000269|PubMed:12047556,ECO:0000269|PubMed:12808027, ECO:0000269|PubMed:15616190,ECO:0000269|PubMed:16926190, ECO:0000269|PubMed:17666033,ECO:0000269|PubMed:17956946, ECO:0000269|PubMed:18003980,ECO:0000269|PubMed:18063581, ECO:0000269|PubMed:19461073,ECO:0000269|PubMed:22185782, ECO:0000269|PubMed:22573891,ECO:0000269|PubMed:23386609, ECO:0000269|PubMed:23418352,ECO:0000269|PubMed:24213530, ECO:0000305|PubMed:19039328,ECO:0000305|PubMed:22573891}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 101_123 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 127_149 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 164_184 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 194_214 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 266_288 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 306_326 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 332_354 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 401_421 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 52_72 | 430 | 518 | Transmembrane | Helical |
| Hgene | TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 9_29 | 430 | 518 | Transmembrane | Helical |
| Tgene | >GBF1 | chr10:104233769 | chr10:104111013 | ENST00000369983 | + | 3 | 40 | 1751_1854 | 98 | 1860 | Compositional bias | Note=Pro-rich |
| Tgene | >GBF1 | chr10:104233769 | chr10:104111013 | ENST00000369983 | + | 3 | 40 | 692_882 | 98 | 1860 | Domain | SEC7 |
| Tgene | >GBF1 | chr10:104233769 | chr10:104111013 | ENST00000369983 | + | 3 | 40 | 886_1370 | 98 | 1860 | Region | Phosphatidylinositol-phosphate binding%3B required for translocation to the leading edge and for ARF1 activation upon GPCR signaling |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TMEM180 | chr10:104233769 | chr10:104111013 | ENST00000238936 | + | 9 | 10 | 466_486 | 430 | 518 | Transmembrane | Helical |
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FusionGeneSequence for TMEM180_GBF1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TMEM180_ENST00000366277_chr10_104233769_+_GBF1_ENST00000369983_chr10_104111013_+_1921aa MDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSILLGLSYVAPHLNNLYFLSLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDHLSLLC LFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTDPTHEGTAEGMENMADAVTHA RFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYVGT NMKKLKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSSQ TTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQSS QKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLRV CFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVSGQ LYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGKS GCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDKK MIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQHN HNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDLFTM TWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHRH GDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVALE CIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVERA VVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATARA DAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVGL DLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSSQHA SRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARRQ VRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTILD FMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLASA HLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPII >In-frame_TMEM180_ENST00000238936_chr10_104233769_+_GBF1_ENST00000369983_chr10_104111013_+_2192aa MGLGQPQAWLLGLPTAVVYGSLALFTTILHNVFLLYYVDTFVSVYKINKMAFWVGETVFLLWNSLNDPLFGWLSDRQFLSSQPRSGAGLS SRAVVLARVQALGWHGPLLALSFLAFWVPWAPAGLQFLLCLCLYDGFLTLVDLHHHALLADLALSAHDRTHLNFYCSLFSAAGSLSVFAS YAFWNKEDFSSFRAFCVTLAVSSGLGFLGATQLLRRRVEAARKDPGCSGLVVDSGLCGEELLVGSEEADSITLGRYLRQLARHRNFLWFV SMDLVQVFHCHFNSNFFPLFLEHLLSDHISLSTGSILLGLSYVAPHLNNLYFLSLCRRWGVYAVVRGLFLLKLGLSLLMLLAGPDHLSLL CLFIASNRVFTEGTCKLLTLVVTDLVDEDLVLNHRKQAASALLFGMVALVTKPGQTFAPLLGTWLLCFYTDPTHEGTAEGMENMADAVTH ARFVGTDPASDEVVLMKILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFTRLPQFKEEPKNYVG TNMKKLKMRAGGMSDSSKWKKQKRSPRPPRHMTKVTPGSELPTPNGTTLSSNLTGGMPFIDVPTPISSASSEAASAVVSPSTDSGLEFSS QTTSKEDLTDLEQPGSPGYSTATEPGSSELGVPEQPDLQEGTHVEKSQSASVESIPEVLEECTSPADHSDSASVHDMDYVNPRGVRFTQS SQKEGTALVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLHLLTVALESAPVAQCQTLLGLIKDEMCRHLFQLLSIERLNLYAASLR VCFLLFESMREHLKFQMEMYIKKLMEIITVENPKMPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEELTKLLSKNAFPVSG QLYTTHLLSLDALLTVIDSTEAHCQAKVLNSLTQQEKKETARPSCEIVDGTREASNTERTASDGKAVGMASDIPGLHLPGGGRLPPEHGK SGCSDLEEAVDSGADKKFARKPPRFSCLLPDPRELIEIKNKKKLLITGTEQFNQKPKKGIQFLQEKGLLTIPMDNTEVAQWLRENPRLDK KMIGEFVSDRKNIDLLESFVSTFSFQGLRLDEALRLYLEAFRLPGEAPVIQRLLEAFTERWMNCNGSPFANSDACFSLAYAVIMLNTDQH NHNVRKQNAPMTLEEFRKNLKGVNGGKDFEQDILEDMYHAIKNEEIVMPEEQTGLVRENYVWNVLLHRGATPEGIFLRVPTASYDLDLFT MTWGPTIAALSYVFDKSLEETIIQKAISGFRKCAMISAHYGLSDVFDNLIISLCKFTALSSESIENLPSVFGSNPKAHIAAKTVFHLAHR HGDILREGWKNIMEAMLQLFRAQLLPKAMIEVEDFVDPNGKISLQREETPSNRGESTVLSFVSWLTLSGPEQSSVRGPSTENQEAKRVAL ECIKQCDPEKMITESKFLQLESLQELMKALVSVTPDEETYDEEDAAFCLEMLLRIVLENRDRVGCVWQTVRDHLYHLCVQAQDFCFLVER AVVGLLRLAIRLLRREEISAQVLLSLRILLLMKPSVLSRVSHQVAYGLHELLKTNAANIHSGDDWATLFTLLECIGSGVKPPAALQATAR ADAPDAGAQSDSELPSYHQNDVSLDRGYTSDSEVYTDHGRPGKIHRSATDADVVNSGWLVVGKDDVDNSKPGPSRPGPSPLINQYSLTVG LDLGPHDTKSLLKCVESLSFIVRDAAHITPDNFELCVKTLRIFVEASLNGGCKSQEKRGKSHKYDSKGNRFKKKSKEGSMLRRPRTSSQH ASRGGQSDDDEDEGVPASYHTVSLQVSQDLLDLMHTLHTRAASIYSSWAEEQRHLETGGQKIEADSRTLWAHCWCPLLQGIACLCCDARR QVRMQALTYLQRALLVHDLQKLDALEWESCFNKVLFPLLTKLLENISPADVGGMEETRMRASTLLSKVFLQHLSPLLSLSTFAALWLTIL DFMDKYMHAGSSDLLSEAIPESLKNMLLVMDTAEIFHSADARGGGPSALWEITWERIDCFLPHLRDELFKQTVIQDPMPMEPQGQKPLAS AHLTSAAGDTRTPGHPPPPEIPSELGACDFEKPESPRAASSSSPGSPVASSPSRLSPTPDGPPPLAQPPLILQPLASPLQVGVPPMTLPI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TMEM180_ENST00000366277_chr10_104233769_+_GBF1_ENST00000369983_chr10_104111013_+_5763nt ATGGACCTGGTGCAGGTCTTCCACTGCCACTTCAACAGCAACTTCTTCCCTCTCTTCCTGGAGCATCTGTTGTCCGACCATATCTCCCTT TCCACGGGCTCCATCCTGTTGGGCCTCTCCTATGTCGCTCCCCATCTCAACAACCTCTACTTCCTGTCCCTGTGCCGGCGCTGGGGCGTC TACGCGGTGGTGCGGGGGCTCTTCCTGCTCAAGCTGGGACTTAGCCTGCTCATGTTGTTGGCCGGCCCGGACCACCTCAGCCTGCTGTGC CTCTTCATTGCCAGCAACCGCGTCTTCACTGAGGGCACCTGTAAGCTGCTGACCTTGGTGGTCACTGACCTGGTAGACGAGGACCTGGTG CTGAACCACCGCAAGCAGGCAGCCTCGGCACTCCTCTTTGGCATGGTTGCCTTGGTGACCAAGCCAGGCCAGACCTTTGCCCCGCTGCTG GGCACCTGGCTGCTCTGTTTCTACACAGATCCCACCCATGAGGGCACAGCAGAGGGCATGGAGAACATGGCAGATGCTGTCACCCATGCT CGTTTTGTGGGCACGGATCCTGCCAGTGATGAAGTTGTCCTGATGAAAATCCTTCAGGTTCTACGGACTCTGCTGCTAACCCCAGTGGGT GCCCACCTAACCAATGAATCTGTGTGTGAGATTATGCAGTCTTGCTTCCGGATCTGCTTTGAAATGAGGCTCAGTGAGTTATTGAGAAAA TCCGCAGAGCACACTCTCGTAGACATGGTGCAGCTGCTCTTCACAAGGTTACCTCAGTTTAAAGAAGAACCCAAGAACTATGTGGGGACC AACATGAAGAAGCTGAAAATGAGAGCCGGAGGCATGAGTGATTCATCCAAATGGAAGAAACAGAAGAGATCCCCTCGGCCCCCACGCCAT ATGACCAAAGTCACACCAGGTTCAGAGCTGCCCACTCCCAATGGAACCACCTTATCATCTAACCTCACTGGTGGCATGCCCTTCATTGAT GTGCCCACTCCCATCTCCTCTGCAAGTTCAGAAGCTGCCTCAGCAGTGGTCAGTCCCTCTACAGACAGTGGCCTGGAATTCTCCTCCCAA ACCACTTCCAAGGAAGACCTTACTGATCTAGAGCAACCTGGCTCTCCAGGGTACAGCACAGCTACAGAGCCTGGAAGCAGTGAGCTAGGT GTTCCCGAGCAGCCTGACCTCCAGGAAGGGACCCATGTGGAAAAGTCCCAGTCAGCATCTGTGGAGTCCATCCCTGAAGTGTTAGAGGAG TGCACGTCCCCTGCCGACCACTCTGACTCTGCCTCTGTCCATGACATGGATTACGTCAATCCCCGGGGCGTGCGCTTTACACAGTCCTCC CAGAAAGAAGGCACAGCTTTGGTCCCCTATGGTCTTCCCTGCATCCGCGAGCTCTTCCGCTTCCTCATCTCCCTCACCAATCCACACGAC CGCCATAACTCAGAGGTTATGATTCACATGGGACTGCATTTGCTGACAGTGGCCCTTGAGTCAGCCCCTGTAGCCCAGTGCCAGACCCTC TTGGGCCTCATCAAGGATGAGATGTGCCGTCACTTATTCCAGCTACTCAGCATAGAGCGACTAAACCTTTATGCTGCTTCCCTGCGAGTA TGCTTCCTACTGTTTGAGAGCATGCGAGAGCACCTCAAGTTCCAAATGGAGATGTACATCAAAAAGCTTATGGAGATCATCACTGTGGAG AACCCCAAGATGCCTTATGAGATGAAGGAGATGGCACTGGAGGCCATTGTGCAGCTCTGGCGCATCCCCAGCTTTGTCACAGAGCTCTAC ATCAACTATGATTGTGACTACTACTGTTCCAACCTCTTTGAGGAACTCACAAAGCTGCTGTCCAAGAATGCCTTCCCTGTGTCTGGTCAA CTCTATACAACACACCTACTATCTCTTGATGCCCTATTGACAGTGATTGACAGCACCGAGGCCCACTGCCAGGCTAAAGTCCTCAACAGC CTCACCCAGCAAGAGAAGAAGGAGACAGCCAGACCAAGCTGTGAGATAGTAGATGGCACCCGAGAAGCTAGCAATACTGAGAGAACTGCC AGCGATGGGAAAGCTGTAGGCATGGCCTCAGACATCCCAGGCCTGCATCTGCCAGGTGGAGGGCGGCTGCCACCAGAACATGGGAAATCA GGATGCAGTGATCTGGAGGAAGCTGTTGACTCTGGGGCTGACAAAAAGTTTGCCCGGAAGCCACCCCGATTTTCCTGTCTCCTGCCAGAT CCACGGGAACTAATTGAAATTAAAAACAAAAAGAAGCTGCTAATCACTGGCACAGAGCAGTTCAATCAGAAACCAAAGAAGGGGATTCAG TTTCTGCAAGAGAAAGGCCTCCTCACCATCCCAATGGACAACACAGAGGTTGCTCAGTGGCTCCGAGAGAACCCTCGGCTGGACAAGAAG ATGATTGGAGAGTTTGTGAGTGACCGCAAAAACATTGACCTGTTGGAGAGCTTTGTGAGCACCTTCAGTTTTCAGGGTCTGCGACTGGAC GAAGCCCTCCGCCTCTACCTGGAAGCCTTCCGTTTGCCTGGGGAAGCACCAGTCATCCAGAGGTTGCTGGAGGCATTCACAGAGCGTTGG ATGAATTGTAATGGCTCCCCATTTGCCAATAGCGATGCCTGCTTTTCCCTGGCCTATGCTGTCATCATGCTTAATACTGACCAGCACAAC CACAATGTTCGTAAACAGAATGCACCCATGACCCTGGAGGAGTTTCGCAAAAATCTGAAAGGTGTGAATGGAGGCAAGGACTTTGAGCAA GACATCCTGGAGGACATGTACCATGCCATCAAGAATGAGGAAATTGTAATGCCTGAGGAGCAGACAGGCTTGGTTCGGGAGAACTATGTG TGGAATGTGCTGCTTCATCGAGGTGCCACCCCTGAGGGCATATTCCTGCGTGTGCCTACTGCCAGCTATGATCTTGACCTCTTCACCATG ACCTGGGGCCCCACTATTGCTGCTCTCTCTTATGTCTTTGACAAAAGCCTTGAGGAGACAATCATCCAGAAAGCCATCTCAGGCTTCAGG AAGTGCGCCATGATCTCCGCCCACTATGGCCTCAGCGATGTGTTTGACAATCTCATCATCTCTCTATGCAAATTCACAGCTCTCAGCAGT GAGTCTATTGAGAACCTGCCCAGTGTATTTGGAAGCAACCCTAAAGCCCATATTGCAGCCAAGACAGTATTCCATTTGGCCCATCGTCAT GGTGACATCCTGCGGGAGGGCTGGAAGAATATCATGGAGGCCATGCTGCAGCTCTTCCGAGCCCAACTACTGCCCAAGGCTATGATAGAG GTAGAAGATTTCGTGGATCCCAATGGCAAGATCTCTCTACAGCGGGAAGAGACACCATCAAACCGAGGAGAGTCAACAGTGCTGAGCTTT GTGAGCTGGCTAACACTGAGTGGTCCTGAGCAGTCTAGTGTTCGGGGCCCATCCACTGAAAACCAAGAGGCCAAGAGAGTGGCCTTAGAG TGTATAAAGCAATGTGACCCAGAAAAAATGATCACAGAAAGCAAGTTCCTCCAGCTGGAGTCACTACAGGAGCTCATGAAGGCTCTGGTC TCAGTGACACCAGATGAAGAGACATATGATGAGGAAGATGCTGCTTTCTGCCTAGAGATGCTGCTAAGGATTGTGTTGGAGAACAGGGAT CGTGTGGGCTGTGTGTGGCAGACTGTTCGAGACCATCTATACCACCTCTGTGTTCAGGCACAAGATTTCTGCTTCCTTGTGGAGCGGGCA GTGGTGGGGTTGCTACGCCTGGCCATTCGGCTTCTCCGGAGAGAAGAGATCAGTGCTCAGGTGCTGCTCTCCCTGCGCATTTTGCTACTG ATGAAGCCCAGTGTGCTATCCCGAGTCAGCCACCAGGTTGCGTATGGGCTCCATGAACTCCTGAAGACCAATGCAGCCAACATCCACTCA GGTGATGACTGGGCCACACTCTTCACACTGCTGGAGTGCATCGGCTCAGGTGTGAAGCCTCCAGCTGCTCTGCAGGCCACAGCCAGGGCA GATGCACCTGATGCCGGGGCCCAGTCAGATAGTGAGCTCCCATCCTACCATCAGAATGACGTGAGCCTGGATCGAGGGTACACTTCCGAC TCAGAGGTCTACACTGACCATGGCAGGCCGGGCAAGATACACCGATCAGCCACAGATGCCGATGTGGTCAACAGTGGTTGGTTAGTGGTT GGGAAGGATGACGTTGATAACTCCAAGCCAGGGCCCAGCCGCCCAGGCCCTTCACCCCTGATCAATCAATACAGCCTAACAGTGGGACTG GATTTGGGGCCACACGACACTAAGTCTCTGCTTAAGTGTGTGGAATCGCTGTCCTTCATTGTGCGTGATGCTGCCCACATCACACCTGAC AACTTTGAGCTCTGCGTCAAGACTCTCCGGATCTTTGTGGAGGCCAGTCTGAATGGCGGATGCAAGTCCCAGGAGAAACGTGGCAAGAGT CACAAATATGACAGCAAAGGGAACCGCTTCAAGAAGAAATCCAAAGAGGGATCAATGCTTCGCCGGCCTCGAACCTCCAGCCAACATGCC TCTCGGGGCGGGCAGAGTGATGATGATGAGGACGAAGGCGTGCCTGCCAGCTACCATACGGTGTCTTTACAGGTCAGTCAGGACTTGCTA GACCTGATGCACACCCTGCACACGCGGGCAGCCTCTATCTACAGCTCATGGGCGGAGGAGCAACGCCACCTGGAGACAGGTGGCCAGAAG ATTGAAGCTGATTCTCGCACCCTCTGGGCCCACTGCTGGTGCCCTTTACTGCAGGGTATTGCCTGCCTGTGCTGCGATGCCCGGCGCCAG GTACGGATGCAGGCACTGACCTATCTGCAGCGAGCACTACTTGTACATGATCTGCAAAAGCTAGATGCCCTGGAATGGGAGTCCTGTTTT AACAAGGTGCTGTTTCCTCTACTTACCAAGCTCTTGGAGAACATCAGCCCTGCAGATGTGGGTGGGATGGAGGAGACCCGGATGAGGGCT TCCACATTGCTCTCTAAGGTCTTCCTGCAGCACCTGTCTCCACTGCTGTCACTCTCTACCTTTGCGGCCCTCTGGCTCACCATCTTGGAC TTCATGGACAAGTACATGCACGCAGGCTCCAGCGACTTACTGTCAGAGGCGATCCCTGAGTCTCTGAAGAACATGCTTCTGGTGATGGAC ACAGCGGAGATTTTCCACAGTGCAGATGCACGGGGAGGCGGCCCCTCGGCCCTCTGGGAGATCACCTGGGAACGCATTGACTGTTTTCTC CCTCACCTACGAGATGAACTCTTCAAGCAGACCGTCATCCAGGACCCCATGCCCATGGAGCCTCAAGGCCAAAAGCCTCTCGCCTCAGCC CACCTGACTTCCGCTGCTGGCGACACTAGGACACCTGGCCATCCACCGCCCCCAGAGATTCCATCTGAGCTGGGGGCCTGTGACTTTGAG AAGCCCGAGAGCCCCCGAGCCGCCAGCAGCAGCTCCCCAGGATCACCAGTGGCCTCAAGCCCCAGCAGGCTGAGCCCCACCCCCGACGGG CCTCCACCCTTGGCTCAGCCCCCACTGATCCTGCAGCCCTTGGCCTCCCCACTGCAGGTGGGCGTGCCACCTATGACTCTGCCCATCATC CTCAACCCTGCGCTCATCGAGGCCACCTCACCAGTGCCCCTCCTGGCCACACCCCGCCCCACAGATCCCATACCCACCTCTGAGGTCAAC >In-frame_TMEM180_ENST00000238936_chr10_104233769_+_GBF1_ENST00000369983_chr10_104111013_+_6576nt ATGGGGCTGGGTCAGCCCCAGGCCTGGTTGCTGGGTCTGCCCACAGCTGTGGTCTATGGCTCCCTGGCTCTCTTCACCACCATCCTGCAC AATGTCTTCCTGCTCTACTATGTGGACACCTTTGTCTCAGTGTACAAGATCAACAAAATGGCCTTCTGGGTCGGAGAGACAGTGTTTCTC CTCTGGAACAGCCTCAATGACCCCCTCTTCGGTTGGCTCAGTGACCGGCAGTTCCTCAGCTCCCAGCCCCGGTCAGGCGCCGGGCTCTCC TCAAGGGCTGTGGTGCTGGCCCGGGTGCAGGCCCTGGGCTGGCATGGGCCGCTGCTGGCGCTGTCGTTCCTGGCGTTCTGGGTGCCCTGG GCCCCAGCTGGCCTGCAGTTCTTGCTGTGCCTGTGCCTCTATGATGGCTTCCTGACGCTCGTGGACCTGCACCACCATGCCTTGCTGGCC GACCTGGCCCTCTCAGCCCACGACCGCACCCACCTCAACTTCTACTGCTCCCTCTTCAGCGCGGCCGGCTCCCTCTCTGTCTTTGCATCC TATGCCTTTTGGAACAAGGAGGATTTCTCCTCCTTCCGCGCTTTCTGCGTGACACTGGCTGTCAGCTCTGGGCTGGGCTTTCTGGGGGCC ACACAGCTGCTGAGGCGGCGGGTTGAGGCGGCCCGAAAGGACCCAGGGTGCTCAGGCCTGGTTGTGGATAGCGGCCTGTGTGGAGAGGAG CTGCTTGTAGGCAGTGAGGAGGCGGACAGCATCACCTTGGGCCGGTATCTCCGGCAGCTGGCACGCCATCGGAACTTCCTGTGGTTCGTG AGCATGGACCTGGTGCAGGTCTTCCACTGCCACTTCAACAGCAACTTCTTCCCTCTCTTCCTGGAGCATCTGTTGTCCGACCATATCTCC CTTTCCACGGGCTCCATCCTGTTGGGCCTCTCCTATGTCGCTCCCCATCTCAACAACCTCTACTTCCTGTCCCTGTGCCGGCGCTGGGGC GTCTACGCGGTGGTGCGGGGGCTCTTCCTGCTCAAGCTGGGACTTAGCCTGCTCATGTTGTTGGCCGGCCCGGACCACCTCAGCCTGCTG TGCCTCTTCATTGCCAGCAACCGCGTCTTCACTGAGGGCACCTGTAAGCTGCTGACCTTGGTGGTCACTGACCTGGTAGACGAGGACCTG GTGCTGAACCACCGCAAGCAGGCAGCCTCGGCACTCCTCTTTGGCATGGTTGCCTTGGTGACCAAGCCAGGCCAGACCTTTGCCCCGCTG CTGGGCACCTGGCTGCTCTGTTTCTACACAGATCCCACCCATGAGGGCACAGCAGAGGGCATGGAGAACATGGCAGATGCTGTCACCCAT GCTCGTTTTGTGGGCACGGATCCTGCCAGTGATGAAGTTGTCCTGATGAAAATCCTTCAGGTTCTACGGACTCTGCTGCTAACCCCAGTG GGTGCCCACCTAACCAATGAATCTGTGTGTGAGATTATGCAGTCTTGCTTCCGGATCTGCTTTGAAATGAGGCTCAGTGAGTTATTGAGA AAATCCGCAGAGCACACTCTCGTAGACATGGTGCAGCTGCTCTTCACAAGGTTACCTCAGTTTAAAGAAGAACCCAAGAACTATGTGGGG ACCAACATGAAGAAGCTGAAAATGAGAGCCGGAGGCATGAGTGATTCATCCAAATGGAAGAAACAGAAGAGATCCCCTCGGCCCCCACGC CATATGACCAAAGTCACACCAGGTTCAGAGCTGCCCACTCCCAATGGAACCACCTTATCATCTAACCTCACTGGTGGCATGCCCTTCATT GATGTGCCCACTCCCATCTCCTCTGCAAGTTCAGAAGCTGCCTCAGCAGTGGTCAGTCCCTCTACAGACAGTGGCCTGGAATTCTCCTCC CAAACCACTTCCAAGGAAGACCTTACTGATCTAGAGCAACCTGGCTCTCCAGGGTACAGCACAGCTACAGAGCCTGGAAGCAGTGAGCTA GGTGTTCCCGAGCAGCCTGACCTCCAGGAAGGGACCCATGTGGAAAAGTCCCAGTCAGCATCTGTGGAGTCCATCCCTGAAGTGTTAGAG GAGTGCACGTCCCCTGCCGACCACTCTGACTCTGCCTCTGTCCATGACATGGATTACGTCAATCCCCGGGGCGTGCGCTTTACACAGTCC TCCCAGAAAGAAGGCACAGCTTTGGTCCCCTATGGTCTTCCCTGCATCCGCGAGCTCTTCCGCTTCCTCATCTCCCTCACCAATCCACAC GACCGCCATAACTCAGAGGTTATGATTCACATGGGACTGCATTTGCTGACAGTGGCCCTTGAGTCAGCCCCTGTAGCCCAGTGCCAGACC CTCTTGGGCCTCATCAAGGATGAGATGTGCCGTCACTTATTCCAGCTACTCAGCATAGAGCGACTAAACCTTTATGCTGCTTCCCTGCGA GTATGCTTCCTACTGTTTGAGAGCATGCGAGAGCACCTCAAGTTCCAAATGGAGATGTACATCAAAAAGCTTATGGAGATCATCACTGTG GAGAACCCCAAGATGCCTTATGAGATGAAGGAGATGGCACTGGAGGCCATTGTGCAGCTCTGGCGCATCCCCAGCTTTGTCACAGAGCTC TACATCAACTATGATTGTGACTACTACTGTTCCAACCTCTTTGAGGAACTCACAAAGCTGCTGTCCAAGAATGCCTTCCCTGTGTCTGGT CAACTCTATACAACACACCTACTATCTCTTGATGCCCTATTGACAGTGATTGACAGCACCGAGGCCCACTGCCAGGCTAAAGTCCTCAAC AGCCTCACCCAGCAAGAGAAGAAGGAGACAGCCAGACCAAGCTGTGAGATAGTAGATGGCACCCGAGAAGCTAGCAATACTGAGAGAACT GCCAGCGATGGGAAAGCTGTAGGCATGGCCTCAGACATCCCAGGCCTGCATCTGCCAGGTGGAGGGCGGCTGCCACCAGAACATGGGAAA TCAGGATGCAGTGATCTGGAGGAAGCTGTTGACTCTGGGGCTGACAAAAAGTTTGCCCGGAAGCCACCCCGATTTTCCTGTCTCCTGCCA GATCCACGGGAACTAATTGAAATTAAAAACAAAAAGAAGCTGCTAATCACTGGCACAGAGCAGTTCAATCAGAAACCAAAGAAGGGGATT CAGTTTCTGCAAGAGAAAGGCCTCCTCACCATCCCAATGGACAACACAGAGGTTGCTCAGTGGCTCCGAGAGAACCCTCGGCTGGACAAG AAGATGATTGGAGAGTTTGTGAGTGACCGCAAAAACATTGACCTGTTGGAGAGCTTTGTGAGCACCTTCAGTTTTCAGGGTCTGCGACTG GACGAAGCCCTCCGCCTCTACCTGGAAGCCTTCCGTTTGCCTGGGGAAGCACCAGTCATCCAGAGGTTGCTGGAGGCATTCACAGAGCGT TGGATGAATTGTAATGGCTCCCCATTTGCCAATAGCGATGCCTGCTTTTCCCTGGCCTATGCTGTCATCATGCTTAATACTGACCAGCAC AACCACAATGTTCGTAAACAGAATGCACCCATGACCCTGGAGGAGTTTCGCAAAAATCTGAAAGGTGTGAATGGAGGCAAGGACTTTGAG CAAGACATCCTGGAGGACATGTACCATGCCATCAAGAATGAGGAAATTGTAATGCCTGAGGAGCAGACAGGCTTGGTTCGGGAGAACTAT GTGTGGAATGTGCTGCTTCATCGAGGTGCCACCCCTGAGGGCATATTCCTGCGTGTGCCTACTGCCAGCTATGATCTTGACCTCTTCACC ATGACCTGGGGCCCCACTATTGCTGCTCTCTCTTATGTCTTTGACAAAAGCCTTGAGGAGACAATCATCCAGAAAGCCATCTCAGGCTTC AGGAAGTGCGCCATGATCTCCGCCCACTATGGCCTCAGCGATGTGTTTGACAATCTCATCATCTCTCTATGCAAATTCACAGCTCTCAGC AGTGAGTCTATTGAGAACCTGCCCAGTGTATTTGGAAGCAACCCTAAAGCCCATATTGCAGCCAAGACAGTATTCCATTTGGCCCATCGT CATGGTGACATCCTGCGGGAGGGCTGGAAGAATATCATGGAGGCCATGCTGCAGCTCTTCCGAGCCCAACTACTGCCCAAGGCTATGATA GAGGTAGAAGATTTCGTGGATCCCAATGGCAAGATCTCTCTACAGCGGGAAGAGACACCATCAAACCGAGGAGAGTCAACAGTGCTGAGC TTTGTGAGCTGGCTAACACTGAGTGGTCCTGAGCAGTCTAGTGTTCGGGGCCCATCCACTGAAAACCAAGAGGCCAAGAGAGTGGCCTTA GAGTGTATAAAGCAATGTGACCCAGAAAAAATGATCACAGAAAGCAAGTTCCTCCAGCTGGAGTCACTACAGGAGCTCATGAAGGCTCTG GTCTCAGTGACACCAGATGAAGAGACATATGATGAGGAAGATGCTGCTTTCTGCCTAGAGATGCTGCTAAGGATTGTGTTGGAGAACAGG GATCGTGTGGGCTGTGTGTGGCAGACTGTTCGAGACCATCTATACCACCTCTGTGTTCAGGCACAAGATTTCTGCTTCCTTGTGGAGCGG GCAGTGGTGGGGTTGCTACGCCTGGCCATTCGGCTTCTCCGGAGAGAAGAGATCAGTGCTCAGGTGCTGCTCTCCCTGCGCATTTTGCTA CTGATGAAGCCCAGTGTGCTATCCCGAGTCAGCCACCAGGTTGCGTATGGGCTCCATGAACTCCTGAAGACCAATGCAGCCAACATCCAC TCAGGTGATGACTGGGCCACACTCTTCACACTGCTGGAGTGCATCGGCTCAGGTGTGAAGCCTCCAGCTGCTCTGCAGGCCACAGCCAGG GCAGATGCACCTGATGCCGGGGCCCAGTCAGATAGTGAGCTCCCATCCTACCATCAGAATGACGTGAGCCTGGATCGAGGGTACACTTCC GACTCAGAGGTCTACACTGACCATGGCAGGCCGGGCAAGATACACCGATCAGCCACAGATGCCGATGTGGTCAACAGTGGTTGGTTAGTG GTTGGGAAGGATGACGTTGATAACTCCAAGCCAGGGCCCAGCCGCCCAGGCCCTTCACCCCTGATCAATCAATACAGCCTAACAGTGGGA CTGGATTTGGGGCCACACGACACTAAGTCTCTGCTTAAGTGTGTGGAATCGCTGTCCTTCATTGTGCGTGATGCTGCCCACATCACACCT GACAACTTTGAGCTCTGCGTCAAGACTCTCCGGATCTTTGTGGAGGCCAGTCTGAATGGCGGATGCAAGTCCCAGGAGAAACGTGGCAAG AGTCACAAATATGACAGCAAAGGGAACCGCTTCAAGAAGAAATCCAAAGAGGGATCAATGCTTCGCCGGCCTCGAACCTCCAGCCAACAT GCCTCTCGGGGCGGGCAGAGTGATGATGATGAGGACGAAGGCGTGCCTGCCAGCTACCATACGGTGTCTTTACAGGTCAGTCAGGACTTG CTAGACCTGATGCACACCCTGCACACGCGGGCAGCCTCTATCTACAGCTCATGGGCGGAGGAGCAACGCCACCTGGAGACAGGTGGCCAG AAGATTGAAGCTGATTCTCGCACCCTCTGGGCCCACTGCTGGTGCCCTTTACTGCAGGGTATTGCCTGCCTGTGCTGCGATGCCCGGCGC CAGGTACGGATGCAGGCACTGACCTATCTGCAGCGAGCACTACTTGTACATGATCTGCAAAAGCTAGATGCCCTGGAATGGGAGTCCTGT TTTAACAAGGTGCTGTTTCCTCTACTTACCAAGCTCTTGGAGAACATCAGCCCTGCAGATGTGGGTGGGATGGAGGAGACCCGGATGAGG GCTTCCACATTGCTCTCTAAGGTCTTCCTGCAGCACCTGTCTCCACTGCTGTCACTCTCTACCTTTGCGGCCCTCTGGCTCACCATCTTG GACTTCATGGACAAGTACATGCACGCAGGCTCCAGCGACTTACTGTCAGAGGCGATCCCTGAGTCTCTGAAGAACATGCTTCTGGTGATG GACACAGCGGAGATTTTCCACAGTGCAGATGCACGGGGAGGCGGCCCCTCGGCCCTCTGGGAGATCACCTGGGAACGCATTGACTGTTTT CTCCCTCACCTACGAGATGAACTCTTCAAGCAGACCGTCATCCAGGACCCCATGCCCATGGAGCCTCAAGGCCAAAAGCCTCTCGCCTCA GCCCACCTGACTTCCGCTGCTGGCGACACTAGGACACCTGGCCATCCACCGCCCCCAGAGATTCCATCTGAGCTGGGGGCCTGTGACTTT GAGAAGCCCGAGAGCCCCCGAGCCGCCAGCAGCAGCTCCCCAGGATCACCAGTGGCCTCAAGCCCCAGCAGGCTGAGCCCCACCCCCGAC GGGCCTCCACCCTTGGCTCAGCCCCCACTGATCCTGCAGCCCTTGGCCTCCCCACTGCAGGTGGGCGTGCCACCTATGACTCTGCCCATC ATCCTCAACCCTGCGCTCATCGAGGCCACCTCACCAGTGCCCCTCCTGGCCACACCCCGCCCCACAGATCCCATACCCACCTCTGAGGTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TMEM180_ENST00000366277_chr10_104233769_+_GBF1_ENST00000369983_chr10_104111013_+_7218nt ATTGGCTCGCACCTGGCTCCCGCCAGCCGTGGGATTAGGCTTCGCCGGCTACGATTGCGGCCCCCATCTTCTGACTTTTCCTCGTGTGAC CCATCTTTTCAAATTCCCTTACCTGAGGAAGGAGCCCGATTACAAGGATATTTACCTGCTCCTACCCTGATCTAGGGACGAGGATGGGAA GACCGCCTGTGGCCATGAGCCCTCCCCGGTGCTCCTGGGGCTAAGGCTGGGGCTGCAGCCATGGGGCTGGGTCAGCCCCAGGCCTGGTTG CTGGGTCTGCCCACAGCTGTGGTCTATGGCTCCCTGGCTCTCTTCACCACCATCCTGCACAATGTCTTCCTGCTCTACTATGTGGACACC TTTGTCTCAGTGTACAAGATCAACAAAATGGCCTTCTGGGTCGGAGAGGCTGGAGTGCAATGGCGCAATCTCAGCTCACTGCAACCTCCG CCTTCGTGGTTCAAGTGATTCTCCTGTCTCAACCTCATGAGTAGATGGGATTACAAGCACCCGCCACCACGCCCGGCTAATTTTTGTATT TTTAGTAGAGACGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGC TGGTGTGAGCCACCAGCGCCTGGCCAGAGTGGGTTTTAGCAGAGGAACTGACACCAGCAAAGGTTTGCAGACAGTGTTTCTCCTCTGGAA CAGCCTCAATGACCCCCTCTTCGGTTGGCTCAGTGACCGGCAGTTCCTCAGCTCCCAGCCCCGCCTGTGTGGAGAGGAGCTGCTTGTAGG CAGTGAGGAGGCGGACAGCATCACCTTGGGCCGGTATCTCCGGCAGCTGGCACGCCATCGGAACTTCCTGTGGTTCGTGAGCATGGACCT GGTGCAGGTCTTCCACTGCCACTTCAACAGCAACTTCTTCCCTCTCTTCCTGGAGCATCTGTTGTCCGACCATATCTCCCTTTCCACGGG CTCCATCCTGTTGGGCCTCTCCTATGTCGCTCCCCATCTCAACAACCTCTACTTCCTGTCCCTGTGCCGGCGCTGGGGCGTCTACGCGGT GGTGCGGGGGCTCTTCCTGCTCAAGCTGGGACTTAGCCTGCTCATGTTGTTGGCCGGCCCGGACCACCTCAGCCTGCTGTGCCTCTTCAT TGCCAGCAACCGCGTCTTCACTGAGGGCACCTGTAAGCTGCTGACCTTGGTGGTCACTGACCTGGTAGACGAGGACCTGGTGCTGAACCA CCGCAAGCAGGCAGCCTCGGCACTCCTCTTTGGCATGGTTGCCTTGGTGACCAAGCCAGGCCAGACCTTTGCCCCGCTGCTGGGCACCTG GCTGCTCTGTTTCTACACAGATCCCACCCATGAGGGCACAGCAGAGGGCATGGAGAACATGGCAGATGCTGTCACCCATGCTCGTTTTGT GGGCACGGATCCTGCCAGTGATGAAGTTGTCCTGATGAAAATCCTTCAGGTTCTACGGACTCTGCTGCTAACCCCAGTGGGTGCCCACCT AACCAATGAATCTGTGTGTGAGATTATGCAGTCTTGCTTCCGGATCTGCTTTGAAATGAGGCTCAGTGAGTTATTGAGAAAATCCGCAGA GCACACTCTCGTAGACATGGTGCAGCTGCTCTTCACAAGGTTACCTCAGTTTAAAGAAGAACCCAAGAACTATGTGGGGACCAACATGAA GAAGCTGAAAATGAGAGCCGGAGGCATGAGTGATTCATCCAAATGGAAGAAACAGAAGAGATCCCCTCGGCCCCCACGCCATATGACCAA AGTCACACCAGGTTCAGAGCTGCCCACTCCCAATGGAACCACCTTATCATCTAACCTCACTGGTGGCATGCCCTTCATTGATGTGCCCAC TCCCATCTCCTCTGCAAGTTCAGAAGCTGCCTCAGCAGTGGTCAGTCCCTCTACAGACAGTGGCCTGGAATTCTCCTCCCAAACCACTTC CAAGGAAGACCTTACTGATCTAGAGCAACCTGGCTCTCCAGGGTACAGCACAGCTACAGAGCCTGGAAGCAGTGAGCTAGGTGTTCCCGA GCAGCCTGACCTCCAGGAAGGGACCCATGTGGAAAAGTCCCAGTCAGCATCTGTGGAGTCCATCCCTGAAGTGTTAGAGGAGTGCACGTC CCCTGCCGACCACTCTGACTCTGCCTCTGTCCATGACATGGATTACGTCAATCCCCGGGGCGTGCGCTTTACACAGTCCTCCCAGAAAGA AGGCACAGCTTTGGTCCCCTATGGTCTTCCCTGCATCCGCGAGCTCTTCCGCTTCCTCATCTCCCTCACCAATCCACACGACCGCCATAA CTCAGAGGTTATGATTCACATGGGACTGCATTTGCTGACAGTGGCCCTTGAGTCAGCCCCTGTAGCCCAGTGCCAGACCCTCTTGGGCCT CATCAAGGATGAGATGTGCCGTCACTTATTCCAGCTACTCAGCATAGAGCGACTAAACCTTTATGCTGCTTCCCTGCGAGTATGCTTCCT ACTGTTTGAGAGCATGCGAGAGCACCTCAAGTTCCAAATGGAGATGTACATCAAAAAGCTTATGGAGATCATCACTGTGGAGAACCCCAA GATGCCTTATGAGATGAAGGAGATGGCACTGGAGGCCATTGTGCAGCTCTGGCGCATCCCCAGCTTTGTCACAGAGCTCTACATCAACTA TGATTGTGACTACTACTGTTCCAACCTCTTTGAGGAACTCACAAAGCTGCTGTCCAAGAATGCCTTCCCTGTGTCTGGTCAACTCTATAC AACACACCTACTATCTCTTGATGCCCTATTGACAGTGATTGACAGCACCGAGGCCCACTGCCAGGCTAAAGTCCTCAACAGCCTCACCCA GCAAGAGAAGAAGGAGACAGCCAGACCAAGCTGTGAGATAGTAGATGGCACCCGAGAAGCTAGCAATACTGAGAGAACTGCCAGCGATGG GAAAGCTGTAGGCATGGCCTCAGACATCCCAGGCCTGCATCTGCCAGGTGGAGGGCGGCTGCCACCAGAACATGGGAAATCAGGATGCAG TGATCTGGAGGAAGCTGTTGACTCTGGGGCTGACAAAAAGTTTGCCCGGAAGCCACCCCGATTTTCCTGTCTCCTGCCAGATCCACGGGA ACTAATTGAAATTAAAAACAAAAAGAAGCTGCTAATCACTGGCACAGAGCAGTTCAATCAGAAACCAAAGAAGGGGATTCAGTTTCTGCA AGAGAAAGGCCTCCTCACCATCCCAATGGACAACACAGAGGTTGCTCAGTGGCTCCGAGAGAACCCTCGGCTGGACAAGAAGATGATTGG AGAGTTTGTGAGTGACCGCAAAAACATTGACCTGTTGGAGAGCTTTGTGAGCACCTTCAGTTTTCAGGGTCTGCGACTGGACGAAGCCCT CCGCCTCTACCTGGAAGCCTTCCGTTTGCCTGGGGAAGCACCAGTCATCCAGAGGTTGCTGGAGGCATTCACAGAGCGTTGGATGAATTG TAATGGCTCCCCATTTGCCAATAGCGATGCCTGCTTTTCCCTGGCCTATGCTGTCATCATGCTTAATACTGACCAGCACAACCACAATGT TCGTAAACAGAATGCACCCATGACCCTGGAGGAGTTTCGCAAAAATCTGAAAGGTGTGAATGGAGGCAAGGACTTTGAGCAAGACATCCT GGAGGACATGTACCATGCCATCAAGAATGAGGAAATTGTAATGCCTGAGGAGCAGACAGGCTTGGTTCGGGAGAACTATGTGTGGAATGT GCTGCTTCATCGAGGTGCCACCCCTGAGGGCATATTCCTGCGTGTGCCTACTGCCAGCTATGATCTTGACCTCTTCACCATGACCTGGGG CCCCACTATTGCTGCTCTCTCTTATGTCTTTGACAAAAGCCTTGAGGAGACAATCATCCAGAAAGCCATCTCAGGCTTCAGGAAGTGCGC CATGATCTCCGCCCACTATGGCCTCAGCGATGTGTTTGACAATCTCATCATCTCTCTATGCAAATTCACAGCTCTCAGCAGTGAGTCTAT TGAGAACCTGCCCAGTGTATTTGGAAGCAACCCTAAAGCCCATATTGCAGCCAAGACAGTATTCCATTTGGCCCATCGTCATGGTGACAT CCTGCGGGAGGGCTGGAAGAATATCATGGAGGCCATGCTGCAGCTCTTCCGAGCCCAACTACTGCCCAAGGCTATGATAGAGGTAGAAGA TTTCGTGGATCCCAATGGCAAGATCTCTCTACAGCGGGAAGAGACACCATCAAACCGAGGAGAGTCAACAGTGCTGAGCTTTGTGAGCTG GCTAACACTGAGTGGTCCTGAGCAGTCTAGTGTTCGGGGCCCATCCACTGAAAACCAAGAGGCCAAGAGAGTGGCCTTAGAGTGTATAAA GCAATGTGACCCAGAAAAAATGATCACAGAAAGCAAGTTCCTCCAGCTGGAGTCACTACAGGAGCTCATGAAGGCTCTGGTCTCAGTGAC ACCAGATGAAGAGACATATGATGAGGAAGATGCTGCTTTCTGCCTAGAGATGCTGCTAAGGATTGTGTTGGAGAACAGGGATCGTGTGGG CTGTGTGTGGCAGACTGTTCGAGACCATCTATACCACCTCTGTGTTCAGGCACAAGATTTCTGCTTCCTTGTGGAGCGGGCAGTGGTGGG GTTGCTACGCCTGGCCATTCGGCTTCTCCGGAGAGAAGAGATCAGTGCTCAGGTGCTGCTCTCCCTGCGCATTTTGCTACTGATGAAGCC CAGTGTGCTATCCCGAGTCAGCCACCAGGTTGCGTATGGGCTCCATGAACTCCTGAAGACCAATGCAGCCAACATCCACTCAGGTGATGA CTGGGCCACACTCTTCACACTGCTGGAGTGCATCGGCTCAGGTGTGAAGCCTCCAGCTGCTCTGCAGGCCACAGCCAGGGCAGATGCACC TGATGCCGGGGCCCAGTCAGATAGTGAGCTCCCATCCTACCATCAGAATGACGTGAGCCTGGATCGAGGGTACACTTCCGACTCAGAGGT CTACACTGACCATGGCAGGCCGGGCAAGATACACCGATCAGCCACAGATGCCGATGTGGTCAACAGTGGTTGGTTAGTGGTTGGGAAGGA TGACGTTGATAACTCCAAGCCAGGGCCCAGCCGCCCAGGCCCTTCACCCCTGATCAATCAATACAGCCTAACAGTGGGACTGGATTTGGG GCCACACGACACTAAGTCTCTGCTTAAGTGTGTGGAATCGCTGTCCTTCATTGTGCGTGATGCTGCCCACATCACACCTGACAACTTTGA GCTCTGCGTCAAGACTCTCCGGATCTTTGTGGAGGCCAGTCTGAATGGCGGATGCAAGTCCCAGGAGAAACGTGGCAAGAGTCACAAATA TGACAGCAAAGGGAACCGCTTCAAGAAGAAATCCAAAGAGGGATCAATGCTTCGCCGGCCTCGAACCTCCAGCCAACATGCCTCTCGGGG CGGGCAGAGTGATGATGATGAGGACGAAGGCGTGCCTGCCAGCTACCATACGGTGTCTTTACAGGTCAGTCAGGACTTGCTAGACCTGAT GCACACCCTGCACACGCGGGCAGCCTCTATCTACAGCTCATGGGCGGAGGAGCAACGCCACCTGGAGACAGGTGGCCAGAAGATTGAAGC TGATTCTCGCACCCTCTGGGCCCACTGCTGGTGCCCTTTACTGCAGGGTATTGCCTGCCTGTGCTGCGATGCCCGGCGCCAGGTACGGAT GCAGGCACTGACCTATCTGCAGCGAGCACTACTTGTACATGATCTGCAAAAGCTAGATGCCCTGGAATGGGAGTCCTGTTTTAACAAGGT GCTGTTTCCTCTACTTACCAAGCTCTTGGAGAACATCAGCCCTGCAGATGTGGGTGGGATGGAGGAGACCCGGATGAGGGCTTCCACATT GCTCTCTAAGGTCTTCCTGCAGCACCTGTCTCCACTGCTGTCACTCTCTACCTTTGCGGCCCTCTGGCTCACCATCTTGGACTTCATGGA CAAGTACATGCACGCAGGCTCCAGCGACTTACTGTCAGAGGCGATCCCTGAGTCTCTGAAGAACATGCTTCTGGTGATGGACACAGCGGA GATTTTCCACAGTGCAGATGCACGGGGAGGCGGCCCCTCGGCCCTCTGGGAGATCACCTGGGAACGCATTGACTGTTTTCTCCCTCACCT ACGAGATGAACTCTTCAAGCAGACCGTCATCCAGGACCCCATGCCCATGGAGCCTCAAGGCCAAAAGCCTCTCGCCTCAGCCCACCTGAC TTCCGCTGCTGGCGACACTAGGACACCTGGCCATCCACCGCCCCCAGAGATTCCATCTGAGCTGGGGGCCTGTGACTTTGAGAAGCCCGA GAGCCCCCGAGCCGCCAGCAGCAGCTCCCCAGGATCACCAGTGGCCTCAAGCCCCAGCAGGCTGAGCCCCACCCCCGACGGGCCTCCACC CTTGGCTCAGCCCCCACTGATCCTGCAGCCCTTGGCCTCCCCACTGCAGGTGGGCGTGCCACCTATGACTCTGCCCATCATCCTCAACCC TGCGCTCATCGAGGCCACCTCACCAGTGCCCCTCCTGGCCACACCCCGCCCCACAGATCCCATACCCACCTCTGAGGTCAACTAAGGCAG GTCACTCAGAGATCAGGACCAGTGCTTCCCACCAGGCTTTCCTTGACCCCACTTCTGGCTGTCCTGCGGGCCACAAGCTCTTCAGGCCAA GTCAGAGCTGCTGTTGCTGCCACTTGGATGGGGACCTGAAAAAGAGAATGTTGATAGCCCCAGCTAAGACCCCCAATCAGCTGTGGGACC TTTTTCCTCCTCTGCGCTCCATTCCTGGGGGTTCAGCCTGAGAGTGAACTCAGCTGTCATCTGCAGCCTCTGCCTCCAGCCCGGCAGCTC TGGGGAGGCATCCGTGTGCCGGCCCTGCAGTGCCTGCCCACGGTCAGGCATTGAAAACTAAGCCCAACCACTCTGCACTTTGTTTCCCAC TCCCATTAGCCCTGGGCCACCTCCTCCAGTTCTTCCTCTTTTACTAATTAGTTGGTCAGTTTGGAGAGTTGACTGGCACCATGGAGGGTA GGCAGGTGGGGGCTGGGTGGGGGACTGCCCACAGGAGCATGTACATATGGAAAAACAGAACAACAGTGGACTTTTTATGATATAATAAAT >In-frame_TMEM180_ENST00000238936_chr10_104233769_+_GBF1_ENST00000369983_chr10_104111013_+_7376nt GGCTCGCACCTGGCTCCCGCCAGCCGTGGGATTAGGCTTCGCCGGCTACGATTGCGGCCCCCATCTTCTGACTTTTCCTCGTGTGACCCA TCTTTTCAAATTCCCTTACCTGAGGAAGGAGCCCGATTACAAGGATATTTACCTGCTCCTACCCTGATCTAGGGACGAGGATGGGAAGAC CGCCTGTGGCCATGAGCCCTCCCCGGTGCTCCTGGGGCTAAGGCTGGGGCTGCAGCCATGGGGCTGGGTCAGCCCCAGGCCTGGTTGCTG GGTCTGCCCACAGCTGTGGTCTATGGCTCCCTGGCTCTCTTCACCACCATCCTGCACAATGTCTTCCTGCTCTACTATGTGGACACCTTT GTCTCAGTGTACAAGATCAACAAAATGGCCTTCTGGGTCGGAGAGACAGTGTTTCTCCTCTGGAACAGCCTCAATGACCCCCTCTTCGGT TGGCTCAGTGACCGGCAGTTCCTCAGCTCCCAGCCCCGGTCAGGCGCCGGGCTCTCCTCAAGGGCTGTGGTGCTGGCCCGGGTGCAGGCC CTGGGCTGGCATGGGCCGCTGCTGGCGCTGTCGTTCCTGGCGTTCTGGGTGCCCTGGGCCCCAGCTGGCCTGCAGTTCTTGCTGTGCCTG TGCCTCTATGATGGCTTCCTGACGCTCGTGGACCTGCACCACCATGCCTTGCTGGCCGACCTGGCCCTCTCAGCCCACGACCGCACCCAC CTCAACTTCTACTGCTCCCTCTTCAGCGCGGCCGGCTCCCTCTCTGTCTTTGCATCCTATGCCTTTTGGAACAAGGAGGATTTCTCCTCC TTCCGCGCTTTCTGCGTGACACTGGCTGTCAGCTCTGGGCTGGGCTTTCTGGGGGCCACACAGCTGCTGAGGCGGCGGGTTGAGGCGGCC CGAAAGGACCCAGGGTGCTCAGGCCTGGTTGTGGATAGCGGCCTGTGTGGAGAGGAGCTGCTTGTAGGCAGTGAGGAGGCGGACAGCATC ACCTTGGGCCGGTATCTCCGGCAGCTGGCACGCCATCGGAACTTCCTGTGGTTCGTGAGCATGGACCTGGTGCAGGTCTTCCACTGCCAC TTCAACAGCAACTTCTTCCCTCTCTTCCTGGAGCATCTGTTGTCCGACCATATCTCCCTTTCCACGGGCTCCATCCTGTTGGGCCTCTCC TATGTCGCTCCCCATCTCAACAACCTCTACTTCCTGTCCCTGTGCCGGCGCTGGGGCGTCTACGCGGTGGTGCGGGGGCTCTTCCTGCTC AAGCTGGGACTTAGCCTGCTCATGTTGTTGGCCGGCCCGGACCACCTCAGCCTGCTGTGCCTCTTCATTGCCAGCAACCGCGTCTTCACT GAGGGCACCTGTAAGCTGCTGACCTTGGTGGTCACTGACCTGGTAGACGAGGACCTGGTGCTGAACCACCGCAAGCAGGCAGCCTCGGCA CTCCTCTTTGGCATGGTTGCCTTGGTGACCAAGCCAGGCCAGACCTTTGCCCCGCTGCTGGGCACCTGGCTGCTCTGTTTCTACACAGAT CCCACCCATGAGGGCACAGCAGAGGGCATGGAGAACATGGCAGATGCTGTCACCCATGCTCGTTTTGTGGGCACGGATCCTGCCAGTGAT GAAGTTGTCCTGATGAAAATCCTTCAGGTTCTACGGACTCTGCTGCTAACCCCAGTGGGTGCCCACCTAACCAATGAATCTGTGTGTGAG ATTATGCAGTCTTGCTTCCGGATCTGCTTTGAAATGAGGCTCAGTGAGTTATTGAGAAAATCCGCAGAGCACACTCTCGTAGACATGGTG CAGCTGCTCTTCACAAGGTTACCTCAGTTTAAAGAAGAACCCAAGAACTATGTGGGGACCAACATGAAGAAGCTGAAAATGAGAGCCGGA GGCATGAGTGATTCATCCAAATGGAAGAAACAGAAGAGATCCCCTCGGCCCCCACGCCATATGACCAAAGTCACACCAGGTTCAGAGCTG CCCACTCCCAATGGAACCACCTTATCATCTAACCTCACTGGTGGCATGCCCTTCATTGATGTGCCCACTCCCATCTCCTCTGCAAGTTCA GAAGCTGCCTCAGCAGTGGTCAGTCCCTCTACAGACAGTGGCCTGGAATTCTCCTCCCAAACCACTTCCAAGGAAGACCTTACTGATCTA GAGCAACCTGGCTCTCCAGGGTACAGCACAGCTACAGAGCCTGGAAGCAGTGAGCTAGGTGTTCCCGAGCAGCCTGACCTCCAGGAAGGG ACCCATGTGGAAAAGTCCCAGTCAGCATCTGTGGAGTCCATCCCTGAAGTGTTAGAGGAGTGCACGTCCCCTGCCGACCACTCTGACTCT GCCTCTGTCCATGACATGGATTACGTCAATCCCCGGGGCGTGCGCTTTACACAGTCCTCCCAGAAAGAAGGCACAGCTTTGGTCCCCTAT GGTCTTCCCTGCATCCGCGAGCTCTTCCGCTTCCTCATCTCCCTCACCAATCCACACGACCGCCATAACTCAGAGGTTATGATTCACATG GGACTGCATTTGCTGACAGTGGCCCTTGAGTCAGCCCCTGTAGCCCAGTGCCAGACCCTCTTGGGCCTCATCAAGGATGAGATGTGCCGT CACTTATTCCAGCTACTCAGCATAGAGCGACTAAACCTTTATGCTGCTTCCCTGCGAGTATGCTTCCTACTGTTTGAGAGCATGCGAGAG CACCTCAAGTTCCAAATGGAGATGTACATCAAAAAGCTTATGGAGATCATCACTGTGGAGAACCCCAAGATGCCTTATGAGATGAAGGAG ATGGCACTGGAGGCCATTGTGCAGCTCTGGCGCATCCCCAGCTTTGTCACAGAGCTCTACATCAACTATGATTGTGACTACTACTGTTCC AACCTCTTTGAGGAACTCACAAAGCTGCTGTCCAAGAATGCCTTCCCTGTGTCTGGTCAACTCTATACAACACACCTACTATCTCTTGAT GCCCTATTGACAGTGATTGACAGCACCGAGGCCCACTGCCAGGCTAAAGTCCTCAACAGCCTCACCCAGCAAGAGAAGAAGGAGACAGCC AGACCAAGCTGTGAGATAGTAGATGGCACCCGAGAAGCTAGCAATACTGAGAGAACTGCCAGCGATGGGAAAGCTGTAGGCATGGCCTCA GACATCCCAGGCCTGCATCTGCCAGGTGGAGGGCGGCTGCCACCAGAACATGGGAAATCAGGATGCAGTGATCTGGAGGAAGCTGTTGAC TCTGGGGCTGACAAAAAGTTTGCCCGGAAGCCACCCCGATTTTCCTGTCTCCTGCCAGATCCACGGGAACTAATTGAAATTAAAAACAAA AAGAAGCTGCTAATCACTGGCACAGAGCAGTTCAATCAGAAACCAAAGAAGGGGATTCAGTTTCTGCAAGAGAAAGGCCTCCTCACCATC CCAATGGACAACACAGAGGTTGCTCAGTGGCTCCGAGAGAACCCTCGGCTGGACAAGAAGATGATTGGAGAGTTTGTGAGTGACCGCAAA AACATTGACCTGTTGGAGAGCTTTGTGAGCACCTTCAGTTTTCAGGGTCTGCGACTGGACGAAGCCCTCCGCCTCTACCTGGAAGCCTTC CGTTTGCCTGGGGAAGCACCAGTCATCCAGAGGTTGCTGGAGGCATTCACAGAGCGTTGGATGAATTGTAATGGCTCCCCATTTGCCAAT AGCGATGCCTGCTTTTCCCTGGCCTATGCTGTCATCATGCTTAATACTGACCAGCACAACCACAATGTTCGTAAACAGAATGCACCCATG ACCCTGGAGGAGTTTCGCAAAAATCTGAAAGGTGTGAATGGAGGCAAGGACTTTGAGCAAGACATCCTGGAGGACATGTACCATGCCATC AAGAATGAGGAAATTGTAATGCCTGAGGAGCAGACAGGCTTGGTTCGGGAGAACTATGTGTGGAATGTGCTGCTTCATCGAGGTGCCACC CCTGAGGGCATATTCCTGCGTGTGCCTACTGCCAGCTATGATCTTGACCTCTTCACCATGACCTGGGGCCCCACTATTGCTGCTCTCTCT TATGTCTTTGACAAAAGCCTTGAGGAGACAATCATCCAGAAAGCCATCTCAGGCTTCAGGAAGTGCGCCATGATCTCCGCCCACTATGGC CTCAGCGATGTGTTTGACAATCTCATCATCTCTCTATGCAAATTCACAGCTCTCAGCAGTGAGTCTATTGAGAACCTGCCCAGTGTATTT GGAAGCAACCCTAAAGCCCATATTGCAGCCAAGACAGTATTCCATTTGGCCCATCGTCATGGTGACATCCTGCGGGAGGGCTGGAAGAAT ATCATGGAGGCCATGCTGCAGCTCTTCCGAGCCCAACTACTGCCCAAGGCTATGATAGAGGTAGAAGATTTCGTGGATCCCAATGGCAAG ATCTCTCTACAGCGGGAAGAGACACCATCAAACCGAGGAGAGTCAACAGTGCTGAGCTTTGTGAGCTGGCTAACACTGAGTGGTCCTGAG CAGTCTAGTGTTCGGGGCCCATCCACTGAAAACCAAGAGGCCAAGAGAGTGGCCTTAGAGTGTATAAAGCAATGTGACCCAGAAAAAATG ATCACAGAAAGCAAGTTCCTCCAGCTGGAGTCACTACAGGAGCTCATGAAGGCTCTGGTCTCAGTGACACCAGATGAAGAGACATATGAT GAGGAAGATGCTGCTTTCTGCCTAGAGATGCTGCTAAGGATTGTGTTGGAGAACAGGGATCGTGTGGGCTGTGTGTGGCAGACTGTTCGA GACCATCTATACCACCTCTGTGTTCAGGCACAAGATTTCTGCTTCCTTGTGGAGCGGGCAGTGGTGGGGTTGCTACGCCTGGCCATTCGG CTTCTCCGGAGAGAAGAGATCAGTGCTCAGGTGCTGCTCTCCCTGCGCATTTTGCTACTGATGAAGCCCAGTGTGCTATCCCGAGTCAGC CACCAGGTTGCGTATGGGCTCCATGAACTCCTGAAGACCAATGCAGCCAACATCCACTCAGGTGATGACTGGGCCACACTCTTCACACTG CTGGAGTGCATCGGCTCAGGTGTGAAGCCTCCAGCTGCTCTGCAGGCCACAGCCAGGGCAGATGCACCTGATGCCGGGGCCCAGTCAGAT AGTGAGCTCCCATCCTACCATCAGAATGACGTGAGCCTGGATCGAGGGTACACTTCCGACTCAGAGGTCTACACTGACCATGGCAGGCCG GGCAAGATACACCGATCAGCCACAGATGCCGATGTGGTCAACAGTGGTTGGTTAGTGGTTGGGAAGGATGACGTTGATAACTCCAAGCCA GGGCCCAGCCGCCCAGGCCCTTCACCCCTGATCAATCAATACAGCCTAACAGTGGGACTGGATTTGGGGCCACACGACACTAAGTCTCTG CTTAAGTGTGTGGAATCGCTGTCCTTCATTGTGCGTGATGCTGCCCACATCACACCTGACAACTTTGAGCTCTGCGTCAAGACTCTCCGG ATCTTTGTGGAGGCCAGTCTGAATGGCGGATGCAAGTCCCAGGAGAAACGTGGCAAGAGTCACAAATATGACAGCAAAGGGAACCGCTTC AAGAAGAAATCCAAAGAGGGATCAATGCTTCGCCGGCCTCGAACCTCCAGCCAACATGCCTCTCGGGGCGGGCAGAGTGATGATGATGAG GACGAAGGCGTGCCTGCCAGCTACCATACGGTGTCTTTACAGGTCAGTCAGGACTTGCTAGACCTGATGCACACCCTGCACACGCGGGCA GCCTCTATCTACAGCTCATGGGCGGAGGAGCAACGCCACCTGGAGACAGGTGGCCAGAAGATTGAAGCTGATTCTCGCACCCTCTGGGCC CACTGCTGGTGCCCTTTACTGCAGGGTATTGCCTGCCTGTGCTGCGATGCCCGGCGCCAGGTACGGATGCAGGCACTGACCTATCTGCAG CGAGCACTACTTGTACATGATCTGCAAAAGCTAGATGCCCTGGAATGGGAGTCCTGTTTTAACAAGGTGCTGTTTCCTCTACTTACCAAG CTCTTGGAGAACATCAGCCCTGCAGATGTGGGTGGGATGGAGGAGACCCGGATGAGGGCTTCCACATTGCTCTCTAAGGTCTTCCTGCAG CACCTGTCTCCACTGCTGTCACTCTCTACCTTTGCGGCCCTCTGGCTCACCATCTTGGACTTCATGGACAAGTACATGCACGCAGGCTCC AGCGACTTACTGTCAGAGGCGATCCCTGAGTCTCTGAAGAACATGCTTCTGGTGATGGACACAGCGGAGATTTTCCACAGTGCAGATGCA CGGGGAGGCGGCCCCTCGGCCCTCTGGGAGATCACCTGGGAACGCATTGACTGTTTTCTCCCTCACCTACGAGATGAACTCTTCAAGCAG ACCGTCATCCAGGACCCCATGCCCATGGAGCCTCAAGGCCAAAAGCCTCTCGCCTCAGCCCACCTGACTTCCGCTGCTGGCGACACTAGG ACACCTGGCCATCCACCGCCCCCAGAGATTCCATCTGAGCTGGGGGCCTGTGACTTTGAGAAGCCCGAGAGCCCCCGAGCCGCCAGCAGC AGCTCCCCAGGATCACCAGTGGCCTCAAGCCCCAGCAGGCTGAGCCCCACCCCCGACGGGCCTCCACCCTTGGCTCAGCCCCCACTGATC CTGCAGCCCTTGGCCTCCCCACTGCAGGTGGGCGTGCCACCTATGACTCTGCCCATCATCCTCAACCCTGCGCTCATCGAGGCCACCTCA CCAGTGCCCCTCCTGGCCACACCCCGCCCCACAGATCCCATACCCACCTCTGAGGTCAACTAAGGCAGGTCACTCAGAGATCAGGACCAG TGCTTCCCACCAGGCTTTCCTTGACCCCACTTCTGGCTGTCCTGCGGGCCACAAGCTCTTCAGGCCAAGTCAGAGCTGCTGTTGCTGCCA CTTGGATGGGGACCTGAAAAAGAGAATGTTGATAGCCCCAGCTAAGACCCCCAATCAGCTGTGGGACCTTTTTCCTCCTCTGCGCTCCAT TCCTGGGGGTTCAGCCTGAGAGTGAACTCAGCTGTCATCTGCAGCCTCTGCCTCCAGCCCGGCAGCTCTGGGGAGGCATCCGTGTGCCGG CCCTGCAGTGCCTGCCCACGGTCAGGCATTGAAAACTAAGCCCAACCACTCTGCACTTTGTTTCCCACTCCCATTAGCCCTGGGCCACCT CCTCCAGTTCTTCCTCTTTTACTAATTAGTTGGTCAGTTTGGAGAGTTGACTGGCACCATGGAGGGTAGGCAGGTGGGGGCTGGGTGGGG 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FusionGenePPI for TMEM180_GBF1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TMEM180 | ELAVL1, APP, COL1A1, GNA11 | GBF1 | YWHAG, COPG1, KBTBD7, VCP, HDAC6, EGFR, PNPLA2, YWHAB, BIRC6, EPS15L1, NUP85, PLEC, CCAR2, NCAPH, RABL6, IRS4, IVNS1ABP, FBXW11, BTRC, SPACA1, PNKD, LYPD3, KIF4A, PUS7, RBM26, VARS, NTRK1, SRPK2, FBXO7, ZSCAN26, FOXB1, FOXG1, FOXI2, FOXL1, CDC73, TMEM206, CHRM3, GML, MILR1, DLK2, NPY2R, EPHA1, UBC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | GBF1 | chr10:104233769 | chr10:104111013 | ENST00000369983 | + | 3 | 40 | 1_380 | 98 | 1860 | RAB1B |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TMEM180_GBF1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TMEM180_GBF1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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