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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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Fusion gene ID: 3833

FusionGeneSummary for BAP1_PLXNB1

check button Fusion gene summary
Fusion gene informationFusion gene name: BAP1_PLXNB1
Fusion gene ID: 3833
HgeneTgene
Gene symbol

BAP1

PLXNB1

Gene ID

9223

5364

Gene namemembrane associated guanylate kinase, WW and PDZ domain containing 1plexin B1
SynonymsAIP-3|AIP3|BAIAP1|BAP-1|BAP1|MAGI-1|Magi1d|TNRC19|WWP3PLEXIN-B1|PLXN5|SEP
Cytomap

3p14.1

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionmembrane-associated guanylate kinase, WW and PDZ domain-containing protein 1BAI1-associated protein 1WW domain-containing protein 3atrophin-1-interacting protein 3membrane-associated guanylate kinase inverted 1trinucleotide repeat-containing gene 19 plexin-B1plexin 5semaphorin receptor SEP
Modification date2018051920180523
UniProtAcc

Q92560

O43157

Ensembl transtripts involved in fusion geneENST00000460680, ENST00000296288, 
ENST00000296440, ENST00000358459, 
ENST00000358536, ENST00000448774, 
ENST00000456774, ENST00000465117, 
Fusion gene scores* DoF score8 X 8 X 5=3206 X 6 X 3=108
# samples 85
** MAII scorelog2(8/320*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/108*10)=-1.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BAP1 [Title/Abstract] AND PLXNB1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePLXNB1

GO:0007162

negative regulation of cell adhesion

15218527

TgenePLXNB1

GO:0008360

regulation of cell shape

19843518

TgenePLXNB1

GO:0051493

regulation of cytoskeleton organization

19843518

TgenePLXNB1

GO:0071526

semaphorin-plexin signaling pathway

15218527|19843518


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVMESOTCGA-UD-AABY-01ABAP1chr3

52437154

-PLXNB1chr3

48455480

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000460680ENST00000296440BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000460680ENST00000358459BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000460680ENST00000358536BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000460680ENST00000448774BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000460680ENST00000456774BAP1chr3

52437154

-PLXNB1chr3

48455480

-
5CDS-5UTRENST00000460680ENST00000465117BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000296288ENST00000296440BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000296288ENST00000358459BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000296288ENST00000358536BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000296288ENST00000448774BAP1chr3

52437154

-PLXNB1chr3

48455480

-
In-frameENST00000296288ENST00000456774BAP1chr3

52437154

-PLXNB1chr3

48455480

-
5CDS-5UTRENST00000296288ENST00000465117BAP1chr3

52437154

-PLXNB1chr3

48455480

-

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FusionProtFeatures for BAP1_PLXNB1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BAP1

Q92560

PLXNB1

O43157

Deubiquitinating enzyme that plays a key role inchromatin by mediating deubiquitination of histone H2A and HCFC1.Catalytic component of the PR-DUB complex, a complex thatspecifically mediates deubiquitination of histone H2Amonoubiquitinated at 'Lys-119' (H2AK119ub1). Does notdeubiquitinate monoubiquitinated histone H2B. Acts as a regulatorof cell growth by mediating deubiquitination of HCFC1 N-terminaland C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linkedpolyubiquitin chains. Deubiquitination of HCFC1 does not lead toincrease stability of HCFC1. Interferes with the BRCA1 and BARD1heterodimer activity by inhibiting their ability to mediateubiquitination and autoubiquitination. It however does not mediatedeubiquitination of BRCA1 and BARD1. Able to mediateautodeubiquitination via intramolecular interactions to couteractmonoubiquitination at the nuclear localization signal (NLS),thereby protecting it from cytoplasmic sequestration(PubMed:24703950). Acts as a tumor suppressor.{ECO:0000269|PubMed:12485996, ECO:0000269|PubMed:18757409,ECO:0000269|PubMed:19117993, ECO:0000269|PubMed:19188440,ECO:0000269|PubMed:19815555, ECO:0000269|PubMed:20436459,ECO:0000269|PubMed:24703950, ECO:0000269|PubMed:9528852}. Receptor for SEMA4D. Plays a role in RHOA activation andsubsequent changes of the actin cytoskeleton. Plays a role in axonguidance, invasive growth and cell migration.{ECO:0000269|PubMed:12196628, ECO:0000269|PubMed:12198496,ECO:0000269|PubMed:15210733, ECO:0000269|PubMed:19843518,ECO:0000269|PubMed:20877282, ECO:0000269|PubMed:21912513}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-20381507_153914032136Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-21391507_153912201953Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-20381507_153914032136Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-19371507_153912201953Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-21391252_137512201953DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-19371252_137512201953DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-20381512_213514032136Topological domainCytoplasmic
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-21391512_213512201953Topological domainCytoplasmic
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-20381512_213514032136Topological domainCytoplasmic
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-19371512_213512201953Topological domainCytoplasmic
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-20381491_151114032136TransmembraneHelical
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-21391491_151112201953TransmembraneHelical
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-20381491_151114032136TransmembraneHelical
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-19371491_151112201953TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAP1chr3:52437154chr3:48455480ENST00000460680-1417630_661630730Coiled coilOntology_term=ECO:0000255
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-2038678_82914032136Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-2139678_82912201953Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-2038678_82914032136Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-1937678_82912201953Compositional biasNote=Pro-rich
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-20381070_116014032136DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-20381162_124914032136DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-20381252_137514032136DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-203820_47914032136DomainSema
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-21391070_116012201953DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-21391162_124912201953DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-213920_47912201953DomainSema
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-20381070_116014032136DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-20381162_124914032136DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-20381252_137514032136DomainNote=IPT/TIG 3
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-203820_47914032136DomainSema
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-19371070_116012201953DomainNote=IPT/TIG 1
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-19371162_124912201953DomainNote=IPT/TIG 2
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-193720_47912201953DomainSema
TgenePLXNB1chr3:52437154chr3:48455480ENST00000296440-203820_149014032136Topological domainExtracellular
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358459-213920_149012201953Topological domainExtracellular
TgenePLXNB1chr3:52437154chr3:48455480ENST00000358536-203820_149014032136Topological domainExtracellular
TgenePLXNB1chr3:52437154chr3:48455480ENST00000456774-193720_149012201953Topological domainExtracellular


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FusionGeneSequence for BAP1_PLXNB1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000296440_chr3_48455480_-_1363aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKTEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNTAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAE
KLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR
VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPK
GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGL
GVGTSLLALGVIIIVLMYRRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRES
PLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPK
LMLRRTETVVEKLLTNWMSICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGE
AQGVPVKVLDCDTISQAKEKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCL
TKHVLRENQDTVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILST
SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPI
NKLLTARDIPRYKRMVERYTADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYTDQIITALEEDGTAQKMQLGTRLQQ

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000358459_chr3_48455480_-_1363aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKTEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNTAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAE
KLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR
VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPK
GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGL
GVGTSLLALGVIIIVLMYRRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRES
PLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPK
LMLRRTETVVEKLLTNWMSICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGE
AQGVPVKVLDCDTISQAKEKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCL
TKHVLRENQDTVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILST
SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPI
NKLLTARDIPRYKRMVERYTADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYTDQIITALEEDGTAQKMQLGTRLQQ

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000358536_chr3_48455480_-_1363aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKTEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNTAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAE
KLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR
VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPK
GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGL
GVGTSLLALGVIIIVLMYRRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRES
PLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPK
LMLRRTETVVEKLLTNWMSICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGE
AQGVPVKVLDCDTISQAKEKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCL
TKHVLRENQDTVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILST
SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPI
NKLLTARDIPRYKRMVERYTADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYTDQIITALEEDGTAQKMQLGTRLQQ

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000448774_chr3_48455480_-_1363aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKTEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNTAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAE
KLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR
VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPK
GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGL
GVGTSLLALGVIIIVLMYRRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRES
PLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPK
LMLRRTETVVEKLLTNWMSICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGE
AQGVPVKVLDCDTISQAKEKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCL
TKHVLRENQDTVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILST
SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPI
NKLLTARDIPRYKRMVERYTADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYTDQIITALEEDGTAQKMQLGTRLQQ

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000456774_chr3_48455480_-_1363aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKTEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNTAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAE
KLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLR
VDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPK
GENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGL
GVGTSLLALGVIIIVLMYRRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRES
PLHRDLGVPESRRPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPK
LMLRRTETVVEKLLTNWMSICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGE
AQGVPVKVLDCDTISQAKEKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCL
TKHVLRENQDTVPGERTPMLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILST
SRPVPLAVKYFFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPI
NKLLTARDIPRYKRMVERYTADIRQTVPASDQEMNSVLAELSWNYSGDLGARVALHELYKYINKYTDQIITALEEDGTAQKMQLGTRLQQ

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000296440_chr3_48455480_-_1345aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKTEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNTAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTS
SGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVIS
TGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKGENLDLAMSKEEVVAMIG
DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMY
RRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRESPLHRDLGVPESRRPTVEQ
GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPKLMLRRTETVVEKLLTNWM
SICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAK
EKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDTVPGERTP
MLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQ
AQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLTARDIPRYKRMVER

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000358459_chr3_48455480_-_1345aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKTEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNTAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTS
SGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVIS
TGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKGENLDLAMSKEEVVAMIG
DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMY
RRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRESPLHRDLGVPESRRPTVEQ
GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPKLMLRRTETVVEKLLTNWM
SICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAK
EKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDTVPGERTP
MLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQ
AQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLTARDIPRYKRMVER

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000358536_chr3_48455480_-_1345aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKTEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNTAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTS
SGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVIS
TGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKGENLDLAMSKEEVVAMIG
DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMY
RRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRESPLHRDLGVPESRRPTVEQ
GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPKLMLRRTETVVEKLLTNWM
SICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAK
EKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDTVPGERTP
MLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQ
AQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLTARDIPRYKRMVER

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000448774_chr3_48455480_-_1345aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKTEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNTAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTS
SGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVIS
TGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKGENLDLAMSKEEVVAMIG
DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMY
RRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRESPLHRDLGVPESRRPTVEQ
GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPKLMLRRTETVVEKLLTNWM
SICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAK
EKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDTVPGERTP
MLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQ
AQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLTARDIPRYKRMVER

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000456774_chr3_48455480_-_1345aa
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVTGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGTAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSTVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKTEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNTAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDTEDDEEDDVQNTNSALRTKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTS
SGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVIS
TGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKGENLDLAMSKEEVVAMIG
DGPCVVKTLTRHHLYCEPPVEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQTDGESPGAFPVAAQVGLGVGTSLLALGVIIIVLMY
RRKSKQALRDTKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLGSGIPFLDYKVTAERIFFPGHRESPLHRDLGVPESRRPTVEQ
GLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLETFTDILRTLLSDLVAQTVAKNPKLMLRRTETVVEKLLTNWM
SICLTTFVRDSVGEPLYMLFRGIKHQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCDTISQAK
EKMLDQLTKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNTLQHYKVPDGATVALVPCLTKHVLRENQDTVPGERTP
MLEDVDEGGIRPWHLVKPSDEPEPPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVPLAVKYFFDLLDEQ
AQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIAQTFMDACTLADHKLGRDSPINKLLTARDIPRYKRMVER


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000296440_chr3_48455480_-_4089nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAG
TATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTG
ATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGG
GCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAAC
AAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTT
CTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCA
CCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGG
AAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAG
AAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACA
CACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCT
ATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGT
GTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTG
AGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAG
AAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAG
GGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCAC
CACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTG
CAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTG
GGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAG
AAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGAT
CTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCG
CCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAG
CTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTG
GCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAG
CTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTA
GGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACC
TTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAG
GCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCT
CTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACT
TCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTC
ACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCC
TGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCC
ATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACC
AGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATC
CACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGAT
AACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATC
AACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGC
GACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAG
TACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAG

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000358459_chr3_48455480_-_4089nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAG
TATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTG
ATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGG
GCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAAC
AAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTT
CTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCA
CCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGG
AAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAG
AAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACA
CACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCT
ATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGT
GTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTG
AGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAG
AAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAG
GGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCAC
CACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTG
CAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTG
GGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAG
AAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGAT
CTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCG
CCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAG
CTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTG
GCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAG
CTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTA
GGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACC
TTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAG
GCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCT
CTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACT
TCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTC
ACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCC
TGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCC
ATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACC
AGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATC
CACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGAT
AACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATC
AACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGC
GACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAG
TACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAG

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000358536_chr3_48455480_-_4089nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAG
TATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTG
ATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGG
GCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAAC
AAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTT
CTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCA
CCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGG
AAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAG
AAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACA
CACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCT
ATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGT
GTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTG
AGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAG
AAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAG
GGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCAC
CACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTG
CAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTG
GGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAG
AAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGAT
CTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCG
CCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAG
CTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTG
GCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAG
CTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTA
GGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACC
TTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAG
GCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCT
CTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACT
TCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTC
ACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCC
TGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCC
ATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACC
AGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATC
CACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGAT
AACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATC
AACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGC
GACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAG
TACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAG

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000448774_chr3_48455480_-_4089nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAG
TATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTG
ATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGG
GCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAAC
AAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTT
CTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCA
CCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGG
AAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAG
AAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACA
CACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCT
ATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGT
GTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTG
AGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAG
AAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAG
GGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCAC
CACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTG
CAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTG
GGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAG
AAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGAT
CTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCG
CCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAG
CTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTG
GCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAG
CTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTA
GGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACC
TTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAG
GCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCT
CTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACT
TCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTC
ACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCC
TGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCC
ATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACC
AGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATC
CACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGAT
AACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATC
AACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGC
GACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAG
TACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAG

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000456774_chr3_48455480_-_4089nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAG
TATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTG
ATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGG
GCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAAC
AAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTT
CTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCA
CCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGG
AAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAG
AAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACA
CACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCT
ATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGT
GTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTG
AGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAG
AAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAG
GGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCAC
CACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTG
CAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTG
GGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAG
AAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGAT
CTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCG
CCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAG
CTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTG
GCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAG
CTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTA
GGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACC
TTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAG
GCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCT
CTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACT
TCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTC
ACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCC
TGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCC
ATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACC
AGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATC
CACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGAT
AACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATC
AACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGC
GACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAG
TACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAG

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000296440_chr3_48455480_-_4035nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCT
CTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCC
AGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGT
TCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCC
AACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCG
GCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGAC
GTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCA
GTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGC
AGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAG
ATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCC
AAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGC
ACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCA
ATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCT
GGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGG
GATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTC
CGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGC
CCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTAC
AGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAG
AAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTAT
GCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAA
GGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCT
CGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGT
GACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATG
TCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGG
CCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTG
AATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAG
GAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTG
GCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTC
CCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCA
ATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGC
AGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAG
TTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAG
GCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAA
AACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACC
CTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGG
TACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGAC
CTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACG

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000358459_chr3_48455480_-_4035nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCT
CTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCC
AGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGT
TCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCC
AACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCG
GCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGAC
GTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCA
GTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGC
AGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAG
ATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCC
AAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGC
ACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCA
ATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCT
GGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGG
GATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTC
CGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGC
CCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTAC
AGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAG
AAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTAT
GCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAA
GGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCT
CGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGT
GACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATG
TCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGG
CCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTG
AATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAG
GAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTG
GCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTC
CCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCA
ATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGC
AGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAG
TTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAG
GCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAA
AACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACC
CTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGG
TACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGAC
CTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACG

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000358536_chr3_48455480_-_4035nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCT
CTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCC
AGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGT
TCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCC
AACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCG
GCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGAC
GTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCA
GTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGC
AGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAG
ATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCC
AAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGC
ACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCA
ATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCT
GGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGG
GATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTC
CGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGC
CCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTAC
AGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAG
AAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTAT
GCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAA
GGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCT
CGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGT
GACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATG
TCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGG
CCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTG
AATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAG
GAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTG
GCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTC
CCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCA
ATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGC
AGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAG
TTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAG
GCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAA
AACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACC
CTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGG
TACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGAC
CTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACG

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000448774_chr3_48455480_-_4035nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCT
CTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCC
AGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGT
TCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCC
AACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCG
GCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGAC
GTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCA
GTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGC
AGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAG
ATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCC
AAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGC
ACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCA
ATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCT
GGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGG
GATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTC
CGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGC
CCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTAC
AGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAG
AAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTAT
GCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAA
GGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCT
CGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGT
GACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATG
TCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGG
CCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTG
AATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAG
GAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTG
GCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTC
CCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCA
ATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGC
AGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAG
TTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAG
GCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAA
AACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACC
CTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGG
TACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGAC
CTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACG

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000456774_chr3_48455480_-_4035nt
ATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAG
GAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGA
AAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGCCCACCAGCTGATACCCAACTCT
TGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAGTCGCATGAAGGACTTCACCAAG
GGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGC
CACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTC
TTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATC
ATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCT
CTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCC
AGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGT
TCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCC
AACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCG
GCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGAC
GTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCA
GTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGC
AGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAG
ATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCC
AAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGC
ACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCA
ATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCT
GGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGG
GATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTC
CGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGC
CCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTAC
AGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAG
AAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTAT
GCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAA
GGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCT
CGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGT
GACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATG
TCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGG
CCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTG
AATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAG
GAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTG
GCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTC
CCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCA
ATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGC
AGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAG
TTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAG
GCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAA
AACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACC
CTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGG
TACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGAC
CTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACG


* Fusion transcript sequences (Full-length transcript).
>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000296440_chr3_48455480_-_5193nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAA
CACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAG
TCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTT
CAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGG
AGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCA
CCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCA
GGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAG
TGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGT
GGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGA
CTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCC
TGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAA
GCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGA
CCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTT
CTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCT
CTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTA
CGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCA
GTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTA
TACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGT
GACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGC
TGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGA
CCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCAT
TCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAAC
TGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGT
AGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGG
GGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCT
GTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGG
CATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGT
GTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAA
GCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACAT
CAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGT
GGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCA
GCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCT
TCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGT
GACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGC
CTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGG
CCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTG
CCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTA
GGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGG

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000358459_chr3_48455480_-_5192nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAA
CACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAG
TCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTT
CAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGG
AGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCA
CCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCA
GGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAG
TGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGT
GGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGA
CTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCC
TGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAA
GCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGA
CCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTT
CTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCT
CTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTA
CGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCA
GTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTA
TACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGT
GACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGC
TGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGA
CCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCAT
TCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAAC
TGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGT
AGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGG
GGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCT
GTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGG
CATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGT
GTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAA
GCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACAT
CAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGT
GGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCA
GCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCT
TCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGT
GACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGC
CTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGG
CCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTG
CCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTA
GGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGG

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000358536_chr3_48455480_-_5191nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAA
CACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAG
TCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTT
CAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGG
AGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCA
CCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCA
GGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAG
TGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGT
GGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGA
CTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCC
TGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAA
GCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGA
CCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTT
CTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCT
CTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTA
CGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCA
GTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTA
TACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGT
GACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGC
TGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGA
CCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCAT
TCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAAC
TGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGT
AGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGG
GGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCT
GTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGG
CATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGT
GTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAA
GCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACAT
CAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGT
GGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCA
GCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCT
TCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGGCCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGT
GACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTGGATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGC
CTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCAGGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGG
CCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGGCCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTG
CCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGGCCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTA
GGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCACAGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGG

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000448774_chr3_48455480_-_4602nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAA
CACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAG
TCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTT
CAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGG
AGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCA
CCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCA
GGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAG
TGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGT
GGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGA
CTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCC
TGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAA
GCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGA
CCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTT
CTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCT
CTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTA
CGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCA
GTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTA
TACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGT
GACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGC
TGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGA
CCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCAT
TCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAAC
TGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGT
AGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGG
GGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCT
GTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGG
CATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGT
GTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAA
GCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACAT
CAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGT
GGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCA
GCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAAAACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCT

>In-frame_BAP1_ENST00000460680_chr3_52437154_-_PLXNB1_ENST00000456774_chr3_48455480_-_4561nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAA
CACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAG
TCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTT
CAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGG
AGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCA
CCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCA
GGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAG
TGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTTGCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGT
GGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCCCCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGA
CTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGCTTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCC
TGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTTCTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAA
GCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTGGAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGA
CCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTGGGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTT
CTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTGGGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCT
CTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTCATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTA
CGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTTGAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCA
GTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACAGAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTA
TACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATGCTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGT
GACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTGCTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGC
TGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTGAAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGA
CCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGACCCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCAT
TCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTGTGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAAC
TGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGGGAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGT
AGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCAAGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGG
GGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTGACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCT
GTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTCGCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGG
CATCTCCGACCAGGACACCATCCACATCTGGAAGACCAACAGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGT
GTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTCCTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAA
GCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCACGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACAT
CAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCTGTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGT
GGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTATGACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCA

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000296440_chr3_48455480_-_4703nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCA
GGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAG
AAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCC
ACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCG
ACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTAC
AACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACA
GAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCC
ACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTT
GCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCC
CCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGC
TTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTT
CTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTG
GAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTG
GGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTG
GGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTC
ATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTT
GAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACA
GAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATG
CTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTG
CTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTG
AAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGAC
CCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTG
TGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGG
GAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCA
AGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTG
ACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTC
GCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAAC
AGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTC
CTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCA
CGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCT
GTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTAT
GACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAA
AACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGG
CCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTG
GATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCA
GGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGG
CCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGG
CCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCAC
AGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCATTGACCCAGCTTT

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000358459_chr3_48455480_-_4702nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCA
GGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAG
AAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCC
ACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCG
ACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTAC
AACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACA
GAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCC
ACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTT
GCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCC
CCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGC
TTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTT
CTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTG
GAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTG
GGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTG
GGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTC
ATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTT
GAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACA
GAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATG
CTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTG
CTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTG
AAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGAC
CCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTG
TGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGG
GAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCA
AGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTG
ACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTC
GCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAAC
AGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTC
CTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCA
CGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCT
GTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTAT
GACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAA
AACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGG
CCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTG
GATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCA
GGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGG
CCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGG
CCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCAC
AGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCATTGACCCAGCTTT

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000358536_chr3_48455480_-_4701nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCA
GGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAG
AAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCC
ACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCG
ACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTAC
AACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACA
GAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCC
ACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTT
GCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCC
CCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGC
TTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTT
CTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTG
GAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTG
GGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTG
GGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTC
ATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTT
GAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACA
GAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATG
CTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTG
CTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTG
AAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGAC
CCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTG
TGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGG
GAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCA
AGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTG
ACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTC
GCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAAC
AGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTC
CTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCA
CGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCT
GTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTAT
GACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAA
AACAAGGTCACAGATCTATAGGAACCCAGGAGCCACGGCCTGCTGTTGCTTCAGCCTGGCCTGGGCAGCCCTGGAAGCTCGGAGGAGAGG
CCACCTTCTTAGGTGCCTGTAGTGACTGACAAGCAGAGTTAGTGGAAGGTGACTCCCAGTCTCCTGGTGGCTCTGGCCTCGGCCCTGCTG
GATCCACCTCCTAGACCCGGGGCCTCAAGGCTCATGGGGTAGTACCCAGCCTGCTCCCCGAGTCCAGCGACCCTGTGACACCGGTCTGCA
GGGAGTTGGGGACTAAGGGCTTCCAGAGAGTGGCTGGAAGAGACTCCAGGCCCCTGGGGAGACTGTACTGTTCCTGAACACTGGCCTTGG
CCACACTGGGATTCGGAGAGGAAGGAGGAGAGCCCCATGCTTCCTGTCTGCCTCCTCCACCATCCCTGACCTCAGTTGAGCTGCCTCTGG
CCTTGTTGCTGCTGCCACATCCTAGGTCTAAGAGTTGAACGCCTCTCCTAGGCCACTACAAACTGACCCCTCAGCAGGGCTGGCTGCCAC
AGGGCTGCCCTGCCTCATAGGTAGCCATGGTGAGGGCTATCTGCTGCAGGGGGGTCTTGGGGAGAGTGGTGACTCCATTGACCCAGCTTT

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000448774_chr3_48455480_-_4112nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCA
GGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAG
AAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCC
ACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCG
ACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTAC
AACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACA
GAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCC
ACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTT
GCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCC
CCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGC
TTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTT
CTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTG
GAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTG
GGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTG
GGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTC
ATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTT
GAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACA
GAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATG
CTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTG
CTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTG
AAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGAC
CCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTG
TGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGG
GAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCA
AGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTG
ACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTC
GCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAAC
AGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTC
CTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCA
CGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCT
GTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTAT
GACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAA

>In-frame_BAP1_ENST00000296288_chr3_52437154_-_PLXNB1_ENST00000456774_chr3_48455480_-_4071nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCA
GGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAG
AAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCC
ACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCG
ACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTAC
AACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACA
GAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCC
ACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGGGGAGAACCTGGACCTT
GCAATGTCCAAGGAGGAGGTGGTGGCTATGATAGGGGATGGCCCCTGTGTGGTGAAGACGCTGACGCGGCACCACCTGTACTGCGAGCCC
CCCGTGGAGCAGCCCCTGCCACGGCACCATGCCCTCCGAGAGGCACCTGACTCTTTGCCTGAGTTCACGGTGCAGATGGGGAACTTGCGC
TTCTCCCTGGGTCACGTGCAGTATGACGGCGAGAGCCCTGGGGCTTTTCCTGTGGCAGCCCAGGTGGGCTTGGGGGTGGGCACCTCTCTT
CTGGCTCTGGGTGTCATCATCATTGTCCTCATGTACAGGAGGAAGAGCAAGCAGGCCCTGAGGGACTATAAGAAGGTTCAGATCCAGCTG
GAGAATCTGGAGAGCAGTGTGCGGGACCGCTGCAAGAAGGAATTCACAGACCTCATGACTGAGATGACCGATCTCACCAGTGACCTCCTG
GGCAGCGGCATCCCCTTCCTCGACTACAAGGTGTATGCGGAGAGGATCTTCTTCCCTGGGCACCGCGAGTCGCCCTTGCACCGGGACCTG
GGTGTGCCTGAGAGCAGACGGCCCACTGTGGAGCAAGGGCTGGGGCAGCTCTCTAACCTGCTCAACAGCAAGCTCTTCCTCACCAAGTTC
ATCCACACGCTGGAGAGCCAGCGCACCTTTTCAGCTCGGGACCGTGCCTACGTGGCATCTCTGCTCACCGTGGCACTGCATGGGAAGCTT
GAGTATTTCACTGACATCCTCCGCACTCTGCTCAGTGACCTGGTTGCCCAGTATGTGGCCAAGAACCCCAAGCTGATGCTGCGCAGGACA
GAGACTGTGGTGGAGAAGCTGCTCACCAACTGGATGTCCATCTGTCTGTATACCTTCGTGAGGGACTCCGTAGGGGAGCCTCTGTACATG
CTCTTTCGAGGGATTAAGCACCAAGTGGATAAGGGGCCAGTGGACAGTGTGACAGGCAAGGCCAAATACACCTTGAACGACAACCGCCTG
CTCAGAGAGGATGTGGAGTACCGTCCCCTGACCTTGAATGCACTATTGGCTGTGGGGCCTGGGGCAGGAGAGGCCCAGGGCGTGCCCGTG
AAGGTCCTAGACTGTGACACCATCTCCCAGGCAAAGGAGAAGATGCTGGACCAGCTTTATAAAGGAGTGCCTCTCACCCAGCGGCCAGAC
CCTCGCACCCTTGATGTTGAGTGGCGGTCTGGGGTGGCCGGGCACCTCATTCTTTCTGACGAGGATGTCACTTCTGAGGTCCAGGGTCTG
TGGAGGCGCCTGAACACACTGCAGCATTACAAGGTCCCAGATGGAGCAACTGTGGCCCTCGTCCCCTGCCTCACCAAGCATGTGCTCCGG
GAAAACCAGGATTATGTCCCTGGAGAGCGGACCCCAATGCTGGAGGATGTAGATGAGGGGGGCATCCGGCCCTGGCACCTGGTGAAGCCA
AGTGATGAGCCGGAGCCGCCCAGGCCTCGGAGGGGCAGCCTTCGGGGCGGGGAGCGTGAGCGCGCCAAGGCCATCCCTGAGATCTACCTG
ACCCGCCTGCTGTCCATGAAGGGCACCCTGCAGAAGTTCGTGGATGACCTGTTCCAGGTGATTCTCAGCACCAGCCGCCCCGTGCCGCTC
GCTGTGAAGTACTTCTTTGACCTGCTGGATGAGCAGGCCCAGCAGCATGGCATCTCCGACCAGGACACCATCCACATCTGGAAGACCAAC
AGCTTGCCTCTGAGGTTCTGGATCAATATAATAAAAAACCCGCAGTTTGTGTTCGACGTGCAAACATCTGATAACATGGATGCGGTGCTC
CTTGTCATTGCACAGACCTTCATGGACGCCTGCACCCTGGCCGACCACAAGCTGGGCCGGGACTCCCCGATCAACAAACTTCTGTATGCA
CGGGACATTCCCCGGTACAAGCGGATGGTGGAAAGGTACTATGCAGACATCAGACAGACTGTCCCAGCCAGCGACCAAGAGATGAACTCT
GTCCTGGCTGAACTGTCCTGGAACTACTCCGGAGACCTCGGGGCGCGAGTGGCCCTGCATGAACTCTACAAGTACATCAACAAGTACTAT
GACCAGATCATCACTGCCCTGGAGGAGGATGGCACGGCCCAGAAGATGCAGCTGGGCTATCGGCTCCAGCAGATTGCAGCTGCTGTGGAA


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FusionGenePPI for BAP1_PLXNB1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
BAP1HCFC1, FOXK2, IPO5, PPM1G, RBBP7, OGT, HAT1, EIF4EBP3, PSME3, CBX1, CBX3, AHCYL2, ANKRD17, ANAPC7, ASXL2, UBE2O, IPO4, ASXL1, KDM1B, FOXK1, HSPA2, PTEN, HIST2H2AC, ZC3H13, PRDM10, HSPA9, ZNF131, HSPA1A, EFNA2, ELF2, YY1, BRCA1, TRIM63, USP21, USP15, USP28, USP2, HIST2H2AA3, INO80, UBC, MAP3K1, BAG4, BCAR3, CASP8, ESR1, IGF1R, NBN, PTPRJ, RB1CC1, XRCC3, SMS, TSNAX, KIAA1107, ENTHD2, MCRS1, ASXL3, HIST1H2AB, KLF5, GOPC, CAMK2D, LINC00598PLXNB1ARHGEF11, RND1, RND2, RND3, ARHGEF12, SEMA4D, RHOA, AKT1, GRB2, PLCG1, PLCG2, SOX4, DIAPH1, HNRNPD, SGTB, C21orf59, CENPO, CENPU, SMPX, HBB, HBA2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneBAP1chr3:52437154chr3:48455480ENST00000460680-1417596_721630730BRCA1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for BAP1_PLXNB1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for BAP1_PLXNB1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBAP1C0007134Renal Cell Carcinoma4CTD_human
HgeneBAP1C0025500Mesothelioma4CTD_human
HgeneBAP1C0345967Malignant mesothelioma4CTD_human
HgeneBAP1C0220633Uveal melanoma3CTD_human;HPO
HgeneBAP1C0038356Stomach Neoplasms2CTD_human
HgeneBAP1C0151779Cutaneous Melanoma2CTD_human
HgeneBAP1C0206698Cholangiocarcinoma2CTD_human
HgeneBAP1C1458155Mammary Neoplasms2CTD_human
HgeneBAP1C0005695Bladder Neoplasm1CTD_human
HgeneBAP1C0005967Bone neoplasms1CTD_human
HgeneBAP1C0007117Basal cell carcinoma1CTD_human
HgeneBAP1C0009375Colonic Neoplasms1CTD_human
HgeneBAP1C0018671Head and Neck Neoplasms1CTD_human
HgeneBAP1C0022665Kidney Neoplasm1CTD_human
HgeneBAP1C0023418leukemia1CTD_human
HgeneBAP1C0023798Lipoma1CTD_human
HgeneBAP1C0023903Liver neoplasms1CTD_human
HgeneBAP1C0024121Lung Neoplasms1CTD_human
HgeneBAP1C0025286Meningioma1CTD_human;HPO
HgeneBAP1C0030297Pancreatic Neoplasm1CTD_human
HgeneBAP1C0030421Paraganglioma1CTD_human
HgeneBAP1C0033578Prostatic Neoplasms1CTD_human
HgeneBAP1C0039590Testicular Neoplasms1CTD_human
HgeneBAP1C0040100Thymoma1CTD_human
HgeneBAP1C0042138Uterine Neoplasms1CTD_human
HgeneBAP1C0085136Central Nervous System Neoplasms1CTD_human
HgeneBAP1C0152013Adenocarcinoma of lung (disorder)1CTD_human;HPO
HgeneBAP1C0206686Adrenocortical carcinoma1CTD_human
HgeneBAP1C0206694Mucoepidermoid Carcinoma1CTD_human
HgeneBAP1C0206739Epithelioid and spindle cell nevus1CTD_human
HgeneBAP1C0206754Neuroendocrine Tumors1CTD_human
HgeneBAP1C0206769Nevi and Melanomas1CTD_human
HgeneBAP1C0919267ovarian neoplasm1CTD_human
HgeneBAP1C2931822Nasopharyngeal carcinoma1CTD_human