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Fusion gene ID: 37918 |
FusionGeneSummary for TGFBRAP1_DPP10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TGFBRAP1_DPP10 | Fusion gene ID: 37918 | Hgene | Tgene | Gene symbol | TGFBRAP1 | DPP10 | Gene ID | 9392 | 57628 |
| Gene name | transforming growth factor beta receptor associated protein 1 | dipeptidyl peptidase like 10 | |
| Synonyms | TRAP-1|TRAP1|VPS3 | DPL2|DPPY|DPRP-3|DPRP3 | |
| Cytomap | 2q12.1-q12.2 | 2q14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transforming growth factor-beta receptor-associated protein 1TGF-beta receptor-associated protein 1VPS3 CORVET complex subunit | inactive dipeptidyl peptidase 10DPP Xdipeptidyl peptidase 10dipeptidyl peptidase IV-related protein 3dipeptidyl peptidase Xdipeptidyl peptidase-like protein 2dipeptidyl-peptidase 10 (inactive)dipeptidyl-peptidase 10 (non-functional) | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8WUH2 | Q8N608 | |
| Ensembl transtripts involved in fusion gene | ENST00000393359, ENST00000258449, | ENST00000410059, ENST00000409163, ENST00000393147, ENST00000310323, ENST00000488208, | |
| Fusion gene scores | * DoF score | 4 X 3 X 3=36 | 2 X 3 X 2=12 |
| # samples | 4 | 2 | |
| ** MAII score | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TGFBRAP1 [Title/Abstract] AND DPP10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TGFBRAP1 | GO:0006355 | regulation of transcription, DNA-templated | 11278302 |
| Hgene | TGFBRAP1 | GO:0007165 | signal transduction | 11278302 |
| Tgene | DPP10 | GO:1903078 | positive regulation of protein localization to plasma membrane | 15671030 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A8BU-01A | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| TCGA | LD | SARC | TCGA-DX-A8BU-01A | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000393359 | ENST00000410059 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-5UTR | ENST00000393359 | ENST00000409163 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-5UTR | ENST00000393359 | ENST00000393147 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-5UTR | ENST00000393359 | ENST00000310323 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-intron | ENST00000393359 | ENST00000488208 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| In-frame | ENST00000258449 | ENST00000410059 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-5UTR | ENST00000258449 | ENST00000409163 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-5UTR | ENST00000258449 | ENST00000393147 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-5UTR | ENST00000258449 | ENST00000310323 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-intron | ENST00000258449 | ENST00000488208 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 116066815 | + |
| 5CDS-intron | ENST00000393359 | ENST00000410059 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000393359 | ENST00000409163 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000393359 | ENST00000393147 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000393359 | ENST00000310323 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000393359 | ENST00000488208 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000258449 | ENST00000410059 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000258449 | ENST00000409163 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000258449 | ENST00000393147 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000258449 | ENST00000310323 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
| 5CDS-intron | ENST00000258449 | ENST00000488208 | TGFBRAP1 | chr2 | 105912813 | - | DPP10 | chr2 | 115464694 | + |
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FusionProtFeatures for TGFBRAP1_DPP10 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TGFBRAP1 | DPP10 |
| Plays a role in the TGF-beta/activin signaling pathway.It associates with inactive heteromeric TGF-beta and activinreceptor complexes, mainly through the type II receptor, and isreleased upon activation of signaling. May recruit SMAD4 to thevicinity of the receptor complex and facilitate its interactionwith receptor-regulated Smads, such as SMAD2.{ECO:0000269|PubMed:11278302, ECO:0000269|PubMed:9545258}. Plays a role in vesicle-mediated protein trafficking ofthe endocytic membrane transport pathway. Believed to act as acomponent of the putative CORVET endosomal tethering complexeswhich is proposed to be involved in the Rab5-to-Rab7 endosomeconversion probably implicating MON1A/B, and via binding SNAREsand SNARE complexes to mediate tethering and docking events duringSNARE-mediated membrane fusion. The CORVET complex is proposed tofunction as a Rab5 effector to mediate early endosome fusionprobably in specific endosome subpopulations (PubMed:25266290).Functions predominantly in APPL1-containing endosomes and indegradative but not recycling trafficking of endocytosed cargo(PubMed:25266290). {ECO:0000269|PubMed:25266290,ECO:0000305|PubMed:25266290}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TGFBRAP1 | chr2:105912813 | chr2:116066815 | ENST00000258449 | - | 3 | 11 | 24_297 | 346 | 861 | Domain | CNH |
| Hgene | TGFBRAP1 | chr2:105912813 | chr2:116066815 | ENST00000393359 | - | 4 | 12 | 24_297 | 346 | 861 | Domain | CNH |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000409163 | + | 1 | 27 | 1_56 | -30 | 747 | Region | Note=Mediates effects on KCND2 |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000310323 | + | 0 | 26 | 56_796 | 13 | 790 | Topological domain | Extracellular |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000393147 | + | 0 | 26 | 56_796 | 24 | 801 | Topological domain | Extracellular |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000409163 | + | 1 | 27 | 1_34 | -30 | 747 | Topological domain | Cytoplasmic |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000409163 | + | 1 | 27 | 56_796 | -30 | 747 | Topological domain | Extracellular |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000410059 | + | 0 | 26 | 56_796 | 20 | 797 | Topological domain | Extracellular |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000310323 | + | 0 | 26 | 35_55 | 13 | 790 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000393147 | + | 0 | 26 | 35_55 | 24 | 801 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000409163 | + | 1 | 27 | 35_55 | -30 | 747 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | >DPP10 | chr2:105912813 | chr2:116066815 | ENST00000410059 | + | 0 | 26 | 35_55 | 20 | 797 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TGFBRAP1 | chr2:105912813 | chr2:116066815 | ENST00000258449 | - | 3 | 11 | 564_728 | 346 | 861 | Repeat | Note=CHCR |
| Hgene | >TGFBRAP1 | chr2:105912813 | chr2:116066815 | ENST00000393359 | - | 4 | 12 | 564_728 | 346 | 861 | Repeat | Note=CHCR |
| Tgene | DPP10 | chr2:105912813 | chr2:116066815 | ENST00000310323 | + | 0 | 26 | 1_56 | 13 | 790 | Region | Note=Mediates effects on KCND2 |
| Tgene | DPP10 | chr2:105912813 | chr2:116066815 | ENST00000393147 | + | 0 | 26 | 1_56 | 24 | 801 | Region | Note=Mediates effects on KCND2 |
| Tgene | DPP10 | chr2:105912813 | chr2:116066815 | ENST00000410059 | + | 0 | 26 | 1_56 | 20 | 797 | Region | Note=Mediates effects on KCND2 |
| Tgene | DPP10 | chr2:105912813 | chr2:116066815 | ENST00000310323 | + | 0 | 26 | 1_34 | 13 | 790 | Topological domain | Cytoplasmic |
| Tgene | DPP10 | chr2:105912813 | chr2:116066815 | ENST00000393147 | + | 0 | 26 | 1_34 | 24 | 801 | Topological domain | Cytoplasmic |
| Tgene | DPP10 | chr2:105912813 | chr2:116066815 | ENST00000410059 | + | 0 | 26 | 1_34 | 20 | 797 | Topological domain | Cytoplasmic |
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FusionGeneSequence for TGFBRAP1_DPP10 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TGFBRAP1_ENST00000393359_chr2_105912813_-_DPP10_ENST00000410059_chr2_116066815_+_1123aa MMSIKAFTLVSAVERELLMGDKERVNIECVECCGRDLYVGTNDCFVYHFLLEERPVPAGPATFTATKQLQRHLGFKKPVNELRAASALNR LLVLCDNSISLVNMLNLEPVPSGARIKGAATFALNENPVSGDPFCVEVCIISVKRRTIQMFLVYEDRVQIVKEVSTAEQPLAVAVDGHFL CLALTTQYIIHNYSTGVSQDLFPYCSEERPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVSFPYVIALDDEFITV HSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASRRVEEALVLAKGARRNIPKEKFQELGSNSPPQRNWKG IAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVT FKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLT SSGKEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTH TLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGACSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPVKQGG RGEFHHVAMFLIQSKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQCTYFDASFSP MNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQ LVTDKFHIDWDSVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSD EKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVY >In-frame_TGFBRAP1_ENST00000258449_chr2_105912813_-_DPP10_ENST00000410059_chr2_116066815_+_1123aa MMSIKAFTLVSAVERELLMGDKERVNIECVECCGRDLYVGTNDCFVYHFLLEERPVPAGPATFTATKQLQRHLGFKKPVNELRAASALNR LLVLCDNSISLVNMLNLEPVPSGARIKGAATFALNENPVSGDPFCVEVCIISVKRRTIQMFLVYEDRVQIVKEVSTAEQPLAVAVDGHFL CLALTTQYIIHNYSTGVSQDLFPYCSEERPPIVKRIGRQEFLLAGPGGLGMFATVAGISQRAPVHWSENVIGAAVSFPYVIALDDEFITV HSMLDQQQKQTLPFKEGHILQDFEGRVIVATSKGVYILVPLPLEKQIQDLLASRRVEEALVLAKGARRNIPKEKFQELGSNSPPQRNWKG IAIALLVILVVCSLITMSVILLTPDELTNSSETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVT FKASRHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSSSLRLT SSGKEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFTGALYPKGKQYPYPKAGQVNPTIKLYVVNLYGPTH TLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCETTTGACSKKYEMTSDTWLSQQNEEPVFSRDGSKFFMTVPVKQGG RGEFHHVAMFLIQSKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTESSPRGRQLYSASTEGLLNRQCISCNFMKEQCTYFDASFSP MNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAILKKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQ LVTDKFHIDWDSVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRLSIFGKGYGGYIASMILKSD EKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEESTYQAASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TGFBRAP1_ENST00000393359_chr2_105912813_-_DPP10_ENST00000410059_chr2_116066815_+_3369nt ATGATGAGCATCAAAGCCTTTACGCTTGTCTCTGCTGTGGAGCGGGAGCTGCTGATGGGCGACAAGGAGCGCGTCAACATAGAGTGCGTG GAGTGCTGCGGCAGGGACCTCTACGTGGGCACCAACGACTGCTTCGTCTACCACTTCCTGTTGGAGGAGAGGCCAGTGCCTGCTGGGCCA GCCACGTTCACTGCCACCAAACAGCTGCAGAGACACTTGGGCTTCAAGAAGCCCGTGAACGAGCTGCGTGCGGCCTCAGCACTCAACAGG CTGCTGGTGCTGTGTGACAACTCCATCAGCCTGGTCAACATGCTGAACCTCGAGCCAGTGCCTTCGGGGGCCCGCATCAAGGGGGCAGCC ACGTTTGCACTGAACGAGAACCCTGTGAGTGGGGACCCCTTCTGTGTAGAAGTTTGCATCATCTCTGTCAAACGCAGAACCATCCAGATG TTTCTGGTGTACGAGGACCGGGTGCAGATCGTCAAGGAGGTGTCGACTGCCGAGCAGCCCCTCGCTGTGGCTGTGGACGGCCACTTCCTG TGTCTGGCTCTGACCACTCAGTACATCATCCACAATTACAGCACAGGCGTCTCCCAGGACCTGTTTCCCTACTGCAGTGAGGAGAGGCCG CCGATCGTCAAGAGGATAGGGAGACAGGAGTTCCTGCTGGCGGGCCCCGGAGGGCTGGGCATGTTTGCCACAGTCGCAGGGATATCCCAG CGCGCCCCCGTGCACTGGTCGGAGAATGTGATTGGGGCGGCTGTGTCCTTTCCATACGTCATAGCGCTCGATGACGAATTCATCACAGTC CACAGCATGTTGGATCAGCAACAGAAGCAGACGCTGCCCTTTAAGGAGGGCCATATCCTACAGGACTTTGAAGGAAGAGTGATCGTTGCC ACAAGTAAAGGAGTTTACATCTTGGTTCCATTACCTTTGGAAAAACAAATACAGGATCTTCTAGCAAGCCGCAGAGTAGAAGAGGCTTTG GTTTTAGCAAAAGGAGCCCGGAGGAACATTCCAAAGGAAAAATTTCAGGAACTGGGAAGTAACAGCCCTCCACAGAGAAACTGGAAGGGA ATTGCTATTGCTCTGCTGGTGATTTTAGTTGTATGCTCACTCATCACTATGTCAGTCATCCTCTTAACCCCAGATGAACTCACAAATTCG TCAGAAACCAGATTGTCTTTGGAAGACCTCTTTAGGAAAGACTTTGTGCTTCACGATCCAGAGGCTCGGTGGATCAATGATACAGATGTG GTGTATAAAAGCGAGAATGGACATGTCATTAAACTGAATATAGAAACAAATGCTACCACATTATTATTGGAAAACACAACTTTTGTAACC TTCAAAGCATCAAGACATTCAGTTTCACCAGATTTAAAATATGTCCTTCTGGCATATGATGTCAAACAGATTTTTCATTATTCGTATACT GCTTCATATGTGATTTACAACATACACACTAGGGAAGTTTGGGAGTTAAATCCTCCAGAAGTAGAGGACTCCGTCTTGCAGTACGCGGCC TGGGGTGTCCAAGGGCAGCAGCTGATTTATATTTTTGAAAATAATATCTACTATCAACCTGATATAAAGAGCAGTTCATTGCGACTGACA TCTTCTGGAAAAGAAGAAATAATTTTTAATGGGATTGCTGACTGGTTATATGAAGAGGAACTCCTGCATTCTCACATCGCCCACTGGTGG TCACCAGATGGAGAAAGACTTGCCTTCCTGATGATAAATGACTCTTTGGTACCCACCATGGTTATCCCTCGGTTTACTGGAGCGTTGTAT CCCAAAGGAAAGCAGTATCCGTATCCTAAGGCAGGTCAAGTGAACCCAACAATAAAATTATATGTTGTAAACCTGTATGGACCAACTCAC ACTTTGGAGCTCATGCCACCTGACAGCTTTAAATCAAGAGAATACTATATCACTATGGTTAAATGGGTAAGCAATACCAAGACTGTGGTA AGATGGTTAAACCGAGCTCAGAACATCTCCATCCTCACAGTCTGTGAGACCACTACAGGTGCTTGTAGTAAAAAATATGAGATGACATCA GATACGTGGCTCTCTCAGCAGAATGAGGAGCCCGTGTTTTCTAGAGACGGCAGCAAATTCTTTATGACAGTGCCTGTTAAGCAAGGGGGA CGTGGAGAATTTCACCACGTAGCTATGTTCCTCATCCAGAGTAAAAGTGAGCAAATTACCGTGCGGCATCTGACATCAGGAAACTGGGAA GTGATAAAGATCTTGGCATACGATGAAACTACTCAAAAAATTTACTTTCTGAGCACTGAATCTTCTCCCAGAGGAAGGCAGCTGTACAGT GCTTCTACTGAAGGATTATTGAATCGCCAATGCATTTCATGTAATTTCATGAAAGAACAATGTACATATTTTGATGCCAGTTTTAGTCCC ATGAATCAACATTTCTTATTATTCTGTGAAGGTCCAAGGGTCCCAGTGGTCAGCCTACATAGTACGGACAACCCAGCAAAATATTTTATA TTGGAAAGCAATTCTATGCTGAAGGAAGCTATCCTGAAGAAGAAGATAGGAAAGCCAGAAATTAAAATCCTTCATATTGACGACTATGAA CTTCCTTTACAGTTGTCCCTTCCCAAAGATTTTATGGACCGAAACCAGTATGCTCTTCTGTTAATAATGGATGAAGAACCAGGAGGCCAG CTGGTTACAGATAAGTTCCATATTGACTGGGATTCCGTACTCATTGACATGGATAATGTCATTGTAGCAAGATTTGATGGCAGAGGAAGT GGATTCCAGGGTCTGAAAATTTTGCAGGAGATTCATCGAAGATTAGGTTCAGTAGAAGTAAAGGACCAAATAACAGCTGTGAAATTTTTG CTGAAACTGCCTTACATTGACTCCAAAAGATTAAGCATTTTTGGAAAGGGTTATGGTGGCTATATTGCATCAATGATCTTAAAATCAGAT GAAAAGCTTTTTAAATGTGGATCCGTGGTTGCACCTATCACAGACTTGAAATTGTATGCCTCAGCTTTCTCTGAAAGATACCTTGGGATG CCATCTAAGGAAGAAAGCACTTACCAGGCAGCCAGTGTGCTACATAATGTTCATGGCTTGAAAGAAGAAAATATATTAATAATTCATGGA ACTGCTGACACAAAAGTTCATTTCCAACACTCAGCAGAATTAATCAAGCACCTAATAAAAGCTGGAGTGAATTATACTATGCAGGTCTAC CCAGATGAAGGTCATAACGTATCTGAGAAGAGCAAGTATCATCTCTACAGCACAATCCTCAAATTCTTCAGTGATTGTTTGAAGGAAGAA >In-frame_TGFBRAP1_ENST00000258449_chr2_105912813_-_DPP10_ENST00000410059_chr2_116066815_+_3369nt ATGATGAGCATCAAAGCCTTTACGCTTGTCTCTGCTGTGGAGCGGGAGCTGCTGATGGGCGACAAGGAGCGCGTCAACATAGAGTGCGTG GAGTGCTGCGGCAGGGACCTCTACGTGGGCACCAACGACTGCTTCGTCTACCACTTCCTGTTGGAGGAGAGGCCAGTGCCTGCTGGGCCA GCCACGTTCACTGCCACCAAACAGCTGCAGAGACACTTGGGCTTCAAGAAGCCCGTGAACGAGCTGCGTGCGGCCTCAGCACTCAACAGG CTGCTGGTGCTGTGTGACAACTCCATCAGCCTGGTCAACATGCTGAACCTCGAGCCAGTGCCTTCGGGGGCCCGCATCAAGGGGGCAGCC ACGTTTGCACTGAACGAGAACCCTGTGAGTGGGGACCCCTTCTGTGTAGAAGTTTGCATCATCTCTGTCAAACGCAGAACCATCCAGATG TTTCTGGTGTACGAGGACCGGGTGCAGATCGTCAAGGAGGTGTCGACTGCCGAGCAGCCCCTCGCTGTGGCTGTGGACGGCCACTTCCTG TGTCTGGCTCTGACCACTCAGTACATCATCCACAATTACAGCACAGGCGTCTCCCAGGACCTGTTTCCCTACTGCAGTGAGGAGAGGCCG CCGATCGTCAAGAGGATAGGGAGACAGGAGTTCCTGCTGGCGGGCCCCGGAGGGCTGGGCATGTTTGCCACAGTCGCAGGGATATCCCAG CGCGCCCCCGTGCACTGGTCGGAGAATGTGATTGGGGCGGCTGTGTCCTTTCCATACGTCATAGCGCTCGATGACGAATTCATCACAGTC CACAGCATGTTGGATCAGCAACAGAAGCAGACGCTGCCCTTTAAGGAGGGCCATATCCTACAGGACTTTGAAGGAAGAGTGATCGTTGCC ACAAGTAAAGGAGTTTACATCTTGGTTCCATTACCTTTGGAAAAACAAATACAGGATCTTCTAGCAAGCCGCAGAGTAGAAGAGGCTTTG GTTTTAGCAAAAGGAGCCCGGAGGAACATTCCAAAGGAAAAATTTCAGGAACTGGGAAGTAACAGCCCTCCACAGAGAAACTGGAAGGGA ATTGCTATTGCTCTGCTGGTGATTTTAGTTGTATGCTCACTCATCACTATGTCAGTCATCCTCTTAACCCCAGATGAACTCACAAATTCG TCAGAAACCAGATTGTCTTTGGAAGACCTCTTTAGGAAAGACTTTGTGCTTCACGATCCAGAGGCTCGGTGGATCAATGATACAGATGTG GTGTATAAAAGCGAGAATGGACATGTCATTAAACTGAATATAGAAACAAATGCTACCACATTATTATTGGAAAACACAACTTTTGTAACC TTCAAAGCATCAAGACATTCAGTTTCACCAGATTTAAAATATGTCCTTCTGGCATATGATGTCAAACAGATTTTTCATTATTCGTATACT GCTTCATATGTGATTTACAACATACACACTAGGGAAGTTTGGGAGTTAAATCCTCCAGAAGTAGAGGACTCCGTCTTGCAGTACGCGGCC TGGGGTGTCCAAGGGCAGCAGCTGATTTATATTTTTGAAAATAATATCTACTATCAACCTGATATAAAGAGCAGTTCATTGCGACTGACA TCTTCTGGAAAAGAAGAAATAATTTTTAATGGGATTGCTGACTGGTTATATGAAGAGGAACTCCTGCATTCTCACATCGCCCACTGGTGG TCACCAGATGGAGAAAGACTTGCCTTCCTGATGATAAATGACTCTTTGGTACCCACCATGGTTATCCCTCGGTTTACTGGAGCGTTGTAT CCCAAAGGAAAGCAGTATCCGTATCCTAAGGCAGGTCAAGTGAACCCAACAATAAAATTATATGTTGTAAACCTGTATGGACCAACTCAC ACTTTGGAGCTCATGCCACCTGACAGCTTTAAATCAAGAGAATACTATATCACTATGGTTAAATGGGTAAGCAATACCAAGACTGTGGTA AGATGGTTAAACCGAGCTCAGAACATCTCCATCCTCACAGTCTGTGAGACCACTACAGGTGCTTGTAGTAAAAAATATGAGATGACATCA GATACGTGGCTCTCTCAGCAGAATGAGGAGCCCGTGTTTTCTAGAGACGGCAGCAAATTCTTTATGACAGTGCCTGTTAAGCAAGGGGGA CGTGGAGAATTTCACCACGTAGCTATGTTCCTCATCCAGAGTAAAAGTGAGCAAATTACCGTGCGGCATCTGACATCAGGAAACTGGGAA GTGATAAAGATCTTGGCATACGATGAAACTACTCAAAAAATTTACTTTCTGAGCACTGAATCTTCTCCCAGAGGAAGGCAGCTGTACAGT GCTTCTACTGAAGGATTATTGAATCGCCAATGCATTTCATGTAATTTCATGAAAGAACAATGTACATATTTTGATGCCAGTTTTAGTCCC ATGAATCAACATTTCTTATTATTCTGTGAAGGTCCAAGGGTCCCAGTGGTCAGCCTACATAGTACGGACAACCCAGCAAAATATTTTATA TTGGAAAGCAATTCTATGCTGAAGGAAGCTATCCTGAAGAAGAAGATAGGAAAGCCAGAAATTAAAATCCTTCATATTGACGACTATGAA CTTCCTTTACAGTTGTCCCTTCCCAAAGATTTTATGGACCGAAACCAGTATGCTCTTCTGTTAATAATGGATGAAGAACCAGGAGGCCAG CTGGTTACAGATAAGTTCCATATTGACTGGGATTCCGTACTCATTGACATGGATAATGTCATTGTAGCAAGATTTGATGGCAGAGGAAGT GGATTCCAGGGTCTGAAAATTTTGCAGGAGATTCATCGAAGATTAGGTTCAGTAGAAGTAAAGGACCAAATAACAGCTGTGAAATTTTTG CTGAAACTGCCTTACATTGACTCCAAAAGATTAAGCATTTTTGGAAAGGGTTATGGTGGCTATATTGCATCAATGATCTTAAAATCAGAT GAAAAGCTTTTTAAATGTGGATCCGTGGTTGCACCTATCACAGACTTGAAATTGTATGCCTCAGCTTTCTCTGAAAGATACCTTGGGATG CCATCTAAGGAAGAAAGCACTTACCAGGCAGCCAGTGTGCTACATAATGTTCATGGCTTGAAAGAAGAAAATATATTAATAATTCATGGA ACTGCTGACACAAAAGTTCATTTCCAACACTCAGCAGAATTAATCAAGCACCTAATAAAAGCTGGAGTGAATTATACTATGCAGGTCTAC CCAGATGAAGGTCATAACGTATCTGAGAAGAGCAAGTATCATCTCTACAGCACAATCCTCAAATTCTTCAGTGATTGTTTGAAGGAAGAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TGFBRAP1_ENST00000393359_chr2_105912813_-_DPP10_ENST00000410059_chr2_116066815_+_7203nt CCCGCAGCGGCGGGGGCGGAGAAGAGACCTCAGCCCCGCGGGCTCGCACAGCTGGCGCGGACCACGCTCTCGCCCGGGGCCGGCGGCCTC AGCGCCCCCCGAATGAACACCTTCCGCCCGCTGGCCGCCCCGCGAGGCGGGCCGTGTCGTGGCCCCGGTGCACGGAGGGGGACGCCGAGG CCCGGAGCAGGGCCCGTCTCGGCCTGTGCTCGGAGCCAGGCGGCAGGGCCCGCGGGCCGGCGGGCGGCGCGGAGACGGCTGCGCTCCCGC CCTCCGCCAGCGCCTGGCGGCCGCCCCACGTGACGGGAAGCGGCGGCTGCGGGGTCGGGCCAGCCCAGGAGCCGCGGGCCGGAGCGGGGC GGCGGGGCCCCAGGCCGCGGGGCGGCGCGGGACGGCGGGCGCCGGCGCCGCAGATCAGCCAGTAGACATGATGAGCATCAAAGCCTTTAC GCTTGTCTCTGCTGTGGAGCGGGAGCTGCTGATGGGCGACAAGGAGCGCGTCAACATAGAGTGCGTGGAGTGCTGCGGCAGGGACCTCTA CGTGGGCACCAACGACTGCTTCGTCTACCACTTCCTGTTGGAGGAGAGGCCAGTGCCTGCTGGGCCAGCCACGTTCACTGCCACCAAACA GCTGCAGAGACACTTGGGCTTCAAGAAGCCCGTGAACGAGCTGCGTGCGGCCTCAGCACTCAACAGGCTGCTGGTGCTGTGTGACAACTC CATCAGCCTGGTCAACATGCTGAACCTCGAGCCAGTGCCTTCGGGGGCCCGCATCAAGGGGGCAGCCACGTTTGCACTGAACGAGAACCC TGTGAGTGGGGACCCCTTCTGTGTAGAAGTTTGCATCATCTCTGTCAAACGCAGAACCATCCAGATGTTTCTGGTGTACGAGGACCGGGT GCAGATCGTCAAGGAGGTGTCGACTGCCGAGCAGCCCCTCGCTGTGGCTGTGGACGGCCACTTCCTGTGTCTGGCTCTGACCACTCAGTA CATCATCCACAATTACAGCACAGGCGTCTCCCAGGACCTGTTTCCCTACTGCAGTGAGGAGAGGCCGCCGATCGTCAAGAGGATAGGGAG ACAGGAGTTCCTGCTGGCGGGCCCCGGAGGGCTGGGCATGTTTGCCACAGTCGCAGGGATATCCCAGCGCGCCCCCGTGCACTGGTCGGA GAATGTGATTGGGGCGGCTGTGTCCTTTCCATACGTCATAGCGCTCGATGACGAATTCATCACAGTCCACAGCATGTTGGATCAGCAACA GAAGCAGACGCTGCCCTTTAAGGAGGGCCATATCCTACAGGACTTTGAAGGAAGAGTGATCGTTGCCACAAGTAAAGGAGTTTACATCTT GGTTCCATTACCTTTGGAAAAACAAATACAGGATCTTCTAGCAAGCCGCAGAGTAGAAGAGGCTTTGGTTTTAGCAAAAGGAGCCCGGAG GAACATTCCAAAGGAAAAATTTCAGGAACTGGGAAGTAACAGCCCTCCACAGAGAAACTGGAAGGGAATTGCTATTGCTCTGCTGGTGAT TTTAGTTGTATGCTCACTCATCACTATGTCAGTCATCCTCTTAACCCCAGATGAACTCACAAATTCGTCAGAAACCAGATTGTCTTTGGA AGACCTCTTTAGGAAAGACTTTGTGCTTCACGATCCAGAGGCTCGGTGGATCAATGATACAGATGTGGTGTATAAAAGCGAGAATGGACA TGTCATTAAACTGAATATAGAAACAAATGCTACCACATTATTATTGGAAAACACAACTTTTGTAACCTTCAAAGCATCAAGACATTCAGT TTCACCAGATTTAAAATATGTCCTTCTGGCATATGATGTCAAACAGATTTTTCATTATTCGTATACTGCTTCATATGTGATTTACAACAT ACACACTAGGGAAGTTTGGGAGTTAAATCCTCCAGAAGTAGAGGACTCCGTCTTGCAGTACGCGGCCTGGGGTGTCCAAGGGCAGCAGCT GATTTATATTTTTGAAAATAATATCTACTATCAACCTGATATAAAGAGCAGTTCATTGCGACTGACATCTTCTGGAAAAGAAGAAATAAT TTTTAATGGGATTGCTGACTGGTTATATGAAGAGGAACTCCTGCATTCTCACATCGCCCACTGGTGGTCACCAGATGGAGAAAGACTTGC CTTCCTGATGATAAATGACTCTTTGGTACCCACCATGGTTATCCCTCGGTTTACTGGAGCGTTGTATCCCAAAGGAAAGCAGTATCCGTA TCCTAAGGCAGGTCAAGTGAACCCAACAATAAAATTATATGTTGTAAACCTGTATGGACCAACTCACACTTTGGAGCTCATGCCACCTGA CAGCTTTAAATCAAGAGAATACTATATCACTATGGTTAAATGGGTAAGCAATACCAAGACTGTGGTAAGATGGTTAAACCGAGCTCAGAA CATCTCCATCCTCACAGTCTGTGAGACCACTACAGGTGCTTGTAGTAAAAAATATGAGATGACATCAGATACGTGGCTCTCTCAGCAGAA TGAGGAGCCCGTGTTTTCTAGAGACGGCAGCAAATTCTTTATGACAGTGCCTGTTAAGCAAGGGGGACGTGGAGAATTTCACCACGTAGC TATGTTCCTCATCCAGAGTAAAAGTGAGCAAATTACCGTGCGGCATCTGACATCAGGAAACTGGGAAGTGATAAAGATCTTGGCATACGA TGAAACTACTCAAAAAATTTACTTTCTGAGCACTGAATCTTCTCCCAGAGGAAGGCAGCTGTACAGTGCTTCTACTGAAGGATTATTGAA TCGCCAATGCATTTCATGTAATTTCATGAAAGAACAATGTACATATTTTGATGCCAGTTTTAGTCCCATGAATCAACATTTCTTATTATT CTGTGAAGGTCCAAGGGTCCCAGTGGTCAGCCTACATAGTACGGACAACCCAGCAAAATATTTTATATTGGAAAGCAATTCTATGCTGAA GGAAGCTATCCTGAAGAAGAAGATAGGAAAGCCAGAAATTAAAATCCTTCATATTGACGACTATGAACTTCCTTTACAGTTGTCCCTTCC CAAAGATTTTATGGACCGAAACCAGTATGCTCTTCTGTTAATAATGGATGAAGAACCAGGAGGCCAGCTGGTTACAGATAAGTTCCATAT TGACTGGGATTCCGTACTCATTGACATGGATAATGTCATTGTAGCAAGATTTGATGGCAGAGGAAGTGGATTCCAGGGTCTGAAAATTTT GCAGGAGATTCATCGAAGATTAGGTTCAGTAGAAGTAAAGGACCAAATAACAGCTGTGAAATTTTTGCTGAAACTGCCTTACATTGACTC CAAAAGATTAAGCATTTTTGGAAAGGGTTATGGTGGCTATATTGCATCAATGATCTTAAAATCAGATGAAAAGCTTTTTAAATGTGGATC CGTGGTTGCACCTATCACAGACTTGAAATTGTATGCCTCAGCTTTCTCTGAAAGATACCTTGGGATGCCATCTAAGGAAGAAAGCACTTA CCAGGCAGCCAGTGTGCTACATAATGTTCATGGCTTGAAAGAAGAAAATATATTAATAATTCATGGAACTGCTGACACAAAAGTTCATTT CCAACACTCAGCAGAATTAATCAAGCACCTAATAAAAGCTGGAGTGAATTATACTATGCAGGTCTACCCAGATGAAGGTCATAACGTATC TGAGAAGAGCAAGTATCATCTCTACAGCACAATCCTCAAATTCTTCAGTGATTGTTTGAAGGAAGAAATATCTGTGCTACCACAGGAACC AGAAGAAGATGAATAATGGACTGTATTTATACAGAACTGAAGGGAATATTGAGGCTCAATGAAACCTGACAAAGAGACTGTAATATTGTA GTTGCTCCAGAATGTCAAGGGCAGCTTACGGAGATGTCACTGGAGCAGCACGCTCAGAGACAGTGAACTAGCATTTGAATACACAAGTCC AAGTCTACTGTGTTGCTAGGGGTGCAGAACCCGTTTCTTTGTATGAGAGAGGTCAAAGGGTTGGTTTCCTGGGAGAAATTAGTTTTGCAT TAAAGTAGGAGTAGTGCATGTTTTCTTCTGTTATCCCCCTGTTTGTTCTGTAACTAGTTGCTCTCATTTTAATTTCACTGGCCACCATCA TCTTTGCATATAATGCACAATCTATCATCTGTCCTACAGTCCCTGATCTTTCATGGCTGAGCTGCAATCTAACACTTTACTGTACCTTTA TAATAAGTGCAATTCTTTCATTGTCTATTATTATGCTTAAGAAAATATTCAGTTAATAAAAAACAGAGTATTTTATGTAATTTCTGTTTT TAAAAAGACATTATTAAATGGGTCAAAGGACATATAGAAATGTGGATTTCAGCACCTTCCAAAGTTCAGCCAGTTATCAGTAGATACAAT ATCTTTAAATGAACACACGAGTGTATGTCTCACAATATATATACACAAGTGTGCATATACAGTTAATGAAACTATCTTTAAATGTTATTC ATGCTATAAAGAGTAAACGTTTGATGAATTAGAAGAGATGCTCTTTTCCAAGCTATAATGGATGCTTTGTTTAATGAGCCAAATATGATG AAACATTTTTTCCAATTCAAATTCTAGCTATTGCTTTCCTATAAATGTTTGGGTTGTGTTTGGTATTGTTTTTAGTGGTTAATAGTTTTC CAGTTGCATTTAATTTTTTGAATATGATACCTTGTCACATGTAAATTAGATACTTAAATATTAAATTATAGTTTCTGATAAAGAAATTTT GTTAACAATGCAATGCCACTGAGTGCTATTTTGCTCTTTTGGTGGAGAAGGCTTTTTTCAAAACTCTTGGTCCTTTTACTTCTTTCTCTC AGTGCAGAATCAATTCTCATTTTCATCGTAAAAGCAAATAGCTGGATTATTTCATTTGCCAGTTTCTATTTAGTATTCCATGCCTGCCCA ATTCATCTGTTACTGTTTAATTTCAATTCTTCTGGTGAGAATTAGAAATGAAATATTTTTTATTCATTGGCCAAAAAGTTCACAGACAGC AGTGTTTGCTATTTACTTTGAATTGAAGGCACAAAATGCATCAATTCCTGTGCTGTGTTGACTTGCAGTAGTAAGTAACTGAGAGCATAA AATAAACCTGACTGTATGAAGTCAATTTAAGTGATGAGAACATTTAACTTTGGTGACTAAAGTCAGAATATCTTCTCACTTCACTTAAGG GATCTTCCAGAAGATATCTAAAAGTCTGTAATAAGCTTAGAAGTTCAGATAAATCTAGGCAGGATACTGCATTTTTGTGGTTTTAAAAAA GTCCTTAGGACAGACTGAATTATCATAACTTATGGCATCAGGAGGAAACTTTAAAATATCAAGGAATCACTCAGTCACCCTCCTGTTTTG TTGAAGGATCAACCCCAAATTCTGGGTATTTGAGTACATGTGAATCATGGATTTGGTATTCAACTTTTTCCCTGGATGCTTTGGAATCGT GTCTTCCATGCTCCACTGGGTTCAATTTAAAATAGGAGAGGCTTTCTCTTCTGAAAGATCCATTTTAGGTCTTTTTCAAGAATAGTGAAC ACATTTTTTAACAAAATAAGTTGTAATTTTAAAAGGAAAGTTTTGCCTATTTTATTAAGATGGAAATTTCTTTTTAGGCTAATTTGAAAT CCAACTGAAGCTTTTTAACCAATATTTTAAATTTGAACCACTAGAGTTTTTTATGATGCAAATGATTATGTTGTCTGAAAGGTGTGGTTT TATTGAATGTCTATTTGAGTATCATTTAAAAAGTATTTGCCTTTTACTGTCATCATTTCTCTTGTTTTATTATTATTATCAATGTTTATC TATTTTTCAATTAATTTAATACAGTTTCTAATGTGAAAGACATTTTTCTGGAACCCGTTTTCCCCTTAAACACTAAAGAGACCTCAAGTG AAAGCATATTGCTTAGTAGGAAGGTAGAAAATGTTAATCCCTGCGATTCTTTGAGTTTTAATGACAGGGTCATTTTCAGTAAAGGAAATG CTCACCAACACATAGTCACCAACTATTAAAGGAATCATGTGATTGGATTTTCCCCTGTATACATGTACCCTTGGTCATAATCCCACTATT TCATACATATTTATGCATTGCTAGATTTTCCTAGGACTCCAATAGCATGCTTTCCAAGTGTTATTATTCCCTTAATGTTAAAGAAAAAAA TCAATATATTGAATTCTTTAATTAAATAGGTAAGCAGTATTAAATCATCCACAGAGATAAACAATCTCTTGAAACTCTTTTGAAAGAGAA AAGTGTTTGTTCACTTTCATTGCCTTCATTAAGATCTCCAAATACTCAGAGACTAAGCAGGCTATTCTCATCTCTTTGAGTTTCCTGACA GAACTAAAGGAAGGAATCACTCTTCAAAAGATGGATCTCACTTCACTCTGAAAATGTGCCTTTTTTTAATTGGGTGTTTAGCATAAAAAT CACTATTGGGGATCTTACAGATGTCTGTTGTAGATCTATTACAATGAGGTGACTTAGACATTGGGCTTTACCATATTAGAGAATTACTTA AGCCATTGTCCTTCAAATGTTGGGCTTGGAGACAGAAGTACCTTGGACTGAATTGCTTTCAAGTCTCTAGAATCACTGACAGCACATAGC TTCTATGAGGAGTTATATATGAAATACCACTTGTGTCCCTCCTCAAGTTCTCTGACCACCTTCACATCCTGCGGCCACCAACACTGTATG GATACAATCTGGCCTCTCAGCTCTGCTCACTTTCACTTTCTGTTCTGGGGATTCTCTGATACTAATTTTGGCTACTTGGTAGAACCAAGA GACAAATCGCTTACATGCTGCAAACCGATGTGAAGGTGTTACTAACCCGCTAAAACACAATTAATGAAAGACTGTAGCAGGTAACTGATC TTTCCCTCAGATATTCTACATGGTCCATGGAAGACTCTGTGGGCCGCAGAAGCCCATAGCTGCATACCCTTCTATTTTCCTCTTCCCCAT TTCACTCTTTTAAGCTCCCTACTCCTATTCCCTATGATCACTTTCCAAAATAAACGGCAGGTGTGCTAGCTGTTGTCTTAGACTCTGCTT TCTGGAAACTATTTTTCCCCTCCACAAGAAATTATCACTGTGAATATTACAGGAGGAGAAATAAAATAAGAATAAATCAGTGGTTTATTT >In-frame_TGFBRAP1_ENST00000258449_chr2_105912813_-_DPP10_ENST00000410059_chr2_116066815_+_6796nt CAGCAGATCAGCCAGTAGACATGATGAGCATCAAAGCCTTTACGCTTGTCTCTGCTGTGGAGCGGGAGCTGCTGATGGGCGACAAGGAGC GCGTCAACATAGAGTGCGTGGAGTGCTGCGGCAGGGACCTCTACGTGGGCACCAACGACTGCTTCGTCTACCACTTCCTGTTGGAGGAGA GGCCAGTGCCTGCTGGGCCAGCCACGTTCACTGCCACCAAACAGCTGCAGAGACACTTGGGCTTCAAGAAGCCCGTGAACGAGCTGCGTG CGGCCTCAGCACTCAACAGGCTGCTGGTGCTGTGTGACAACTCCATCAGCCTGGTCAACATGCTGAACCTCGAGCCAGTGCCTTCGGGGG CCCGCATCAAGGGGGCAGCCACGTTTGCACTGAACGAGAACCCTGTGAGTGGGGACCCCTTCTGTGTAGAAGTTTGCATCATCTCTGTCA AACGCAGAACCATCCAGATGTTTCTGGTGTACGAGGACCGGGTGCAGATCGTCAAGGAGGTGTCGACTGCCGAGCAGCCCCTCGCTGTGG CTGTGGACGGCCACTTCCTGTGTCTGGCTCTGACCACTCAGTACATCATCCACAATTACAGCACAGGCGTCTCCCAGGACCTGTTTCCCT ACTGCAGTGAGGAGAGGCCGCCGATCGTCAAGAGGATAGGGAGACAGGAGTTCCTGCTGGCGGGCCCCGGAGGGCTGGGCATGTTTGCCA CAGTCGCAGGGATATCCCAGCGCGCCCCCGTGCACTGGTCGGAGAATGTGATTGGGGCGGCTGTGTCCTTTCCATACGTCATAGCGCTCG ATGACGAATTCATCACAGTCCACAGCATGTTGGATCAGCAACAGAAGCAGACGCTGCCCTTTAAGGAGGGCCATATCCTACAGGACTTTG AAGGAAGAGTGATCGTTGCCACAAGTAAAGGAGTTTACATCTTGGTTCCATTACCTTTGGAAAAACAAATACAGGATCTTCTAGCAAGCC GCAGAGTAGAAGAGGCTTTGGTTTTAGCAAAAGGAGCCCGGAGGAACATTCCAAAGGAAAAATTTCAGGAACTGGGAAGTAACAGCCCTC CACAGAGAAACTGGAAGGGAATTGCTATTGCTCTGCTGGTGATTTTAGTTGTATGCTCACTCATCACTATGTCAGTCATCCTCTTAACCC CAGATGAACTCACAAATTCGTCAGAAACCAGATTGTCTTTGGAAGACCTCTTTAGGAAAGACTTTGTGCTTCACGATCCAGAGGCTCGGT GGATCAATGATACAGATGTGGTGTATAAAAGCGAGAATGGACATGTCATTAAACTGAATATAGAAACAAATGCTACCACATTATTATTGG AAAACACAACTTTTGTAACCTTCAAAGCATCAAGACATTCAGTTTCACCAGATTTAAAATATGTCCTTCTGGCATATGATGTCAAACAGA TTTTTCATTATTCGTATACTGCTTCATATGTGATTTACAACATACACACTAGGGAAGTTTGGGAGTTAAATCCTCCAGAAGTAGAGGACT CCGTCTTGCAGTACGCGGCCTGGGGTGTCCAAGGGCAGCAGCTGATTTATATTTTTGAAAATAATATCTACTATCAACCTGATATAAAGA GCAGTTCATTGCGACTGACATCTTCTGGAAAAGAAGAAATAATTTTTAATGGGATTGCTGACTGGTTATATGAAGAGGAACTCCTGCATT CTCACATCGCCCACTGGTGGTCACCAGATGGAGAAAGACTTGCCTTCCTGATGATAAATGACTCTTTGGTACCCACCATGGTTATCCCTC GGTTTACTGGAGCGTTGTATCCCAAAGGAAAGCAGTATCCGTATCCTAAGGCAGGTCAAGTGAACCCAACAATAAAATTATATGTTGTAA ACCTGTATGGACCAACTCACACTTTGGAGCTCATGCCACCTGACAGCTTTAAATCAAGAGAATACTATATCACTATGGTTAAATGGGTAA GCAATACCAAGACTGTGGTAAGATGGTTAAACCGAGCTCAGAACATCTCCATCCTCACAGTCTGTGAGACCACTACAGGTGCTTGTAGTA AAAAATATGAGATGACATCAGATACGTGGCTCTCTCAGCAGAATGAGGAGCCCGTGTTTTCTAGAGACGGCAGCAAATTCTTTATGACAG TGCCTGTTAAGCAAGGGGGACGTGGAGAATTTCACCACGTAGCTATGTTCCTCATCCAGAGTAAAAGTGAGCAAATTACCGTGCGGCATC TGACATCAGGAAACTGGGAAGTGATAAAGATCTTGGCATACGATGAAACTACTCAAAAAATTTACTTTCTGAGCACTGAATCTTCTCCCA GAGGAAGGCAGCTGTACAGTGCTTCTACTGAAGGATTATTGAATCGCCAATGCATTTCATGTAATTTCATGAAAGAACAATGTACATATT TTGATGCCAGTTTTAGTCCCATGAATCAACATTTCTTATTATTCTGTGAAGGTCCAAGGGTCCCAGTGGTCAGCCTACATAGTACGGACA ACCCAGCAAAATATTTTATATTGGAAAGCAATTCTATGCTGAAGGAAGCTATCCTGAAGAAGAAGATAGGAAAGCCAGAAATTAAAATCC TTCATATTGACGACTATGAACTTCCTTTACAGTTGTCCCTTCCCAAAGATTTTATGGACCGAAACCAGTATGCTCTTCTGTTAATAATGG ATGAAGAACCAGGAGGCCAGCTGGTTACAGATAAGTTCCATATTGACTGGGATTCCGTACTCATTGACATGGATAATGTCATTGTAGCAA GATTTGATGGCAGAGGAAGTGGATTCCAGGGTCTGAAAATTTTGCAGGAGATTCATCGAAGATTAGGTTCAGTAGAAGTAAAGGACCAAA TAACAGCTGTGAAATTTTTGCTGAAACTGCCTTACATTGACTCCAAAAGATTAAGCATTTTTGGAAAGGGTTATGGTGGCTATATTGCAT CAATGATCTTAAAATCAGATGAAAAGCTTTTTAAATGTGGATCCGTGGTTGCACCTATCACAGACTTGAAATTGTATGCCTCAGCTTTCT CTGAAAGATACCTTGGGATGCCATCTAAGGAAGAAAGCACTTACCAGGCAGCCAGTGTGCTACATAATGTTCATGGCTTGAAAGAAGAAA ATATATTAATAATTCATGGAACTGCTGACACAAAAGTTCATTTCCAACACTCAGCAGAATTAATCAAGCACCTAATAAAAGCTGGAGTGA ATTATACTATGCAGGTCTACCCAGATGAAGGTCATAACGTATCTGAGAAGAGCAAGTATCATCTCTACAGCACAATCCTCAAATTCTTCA GTGATTGTTTGAAGGAAGAAATATCTGTGCTACCACAGGAACCAGAAGAAGATGAATAATGGACTGTATTTATACAGAACTGAAGGGAAT ATTGAGGCTCAATGAAACCTGACAAAGAGACTGTAATATTGTAGTTGCTCCAGAATGTCAAGGGCAGCTTACGGAGATGTCACTGGAGCA GCACGCTCAGAGACAGTGAACTAGCATTTGAATACACAAGTCCAAGTCTACTGTGTTGCTAGGGGTGCAGAACCCGTTTCTTTGTATGAG AGAGGTCAAAGGGTTGGTTTCCTGGGAGAAATTAGTTTTGCATTAAAGTAGGAGTAGTGCATGTTTTCTTCTGTTATCCCCCTGTTTGTT CTGTAACTAGTTGCTCTCATTTTAATTTCACTGGCCACCATCATCTTTGCATATAATGCACAATCTATCATCTGTCCTACAGTCCCTGAT CTTTCATGGCTGAGCTGCAATCTAACACTTTACTGTACCTTTATAATAAGTGCAATTCTTTCATTGTCTATTATTATGCTTAAGAAAATA TTCAGTTAATAAAAAACAGAGTATTTTATGTAATTTCTGTTTTTAAAAAGACATTATTAAATGGGTCAAAGGACATATAGAAATGTGGAT TTCAGCACCTTCCAAAGTTCAGCCAGTTATCAGTAGATACAATATCTTTAAATGAACACACGAGTGTATGTCTCACAATATATATACACA AGTGTGCATATACAGTTAATGAAACTATCTTTAAATGTTATTCATGCTATAAAGAGTAAACGTTTGATGAATTAGAAGAGATGCTCTTTT CCAAGCTATAATGGATGCTTTGTTTAATGAGCCAAATATGATGAAACATTTTTTCCAATTCAAATTCTAGCTATTGCTTTCCTATAAATG TTTGGGTTGTGTTTGGTATTGTTTTTAGTGGTTAATAGTTTTCCAGTTGCATTTAATTTTTTGAATATGATACCTTGTCACATGTAAATT AGATACTTAAATATTAAATTATAGTTTCTGATAAAGAAATTTTGTTAACAATGCAATGCCACTGAGTGCTATTTTGCTCTTTTGGTGGAG AAGGCTTTTTTCAAAACTCTTGGTCCTTTTACTTCTTTCTCTCAGTGCAGAATCAATTCTCATTTTCATCGTAAAAGCAAATAGCTGGAT TATTTCATTTGCCAGTTTCTATTTAGTATTCCATGCCTGCCCAATTCATCTGTTACTGTTTAATTTCAATTCTTCTGGTGAGAATTAGAA ATGAAATATTTTTTATTCATTGGCCAAAAAGTTCACAGACAGCAGTGTTTGCTATTTACTTTGAATTGAAGGCACAAAATGCATCAATTC CTGTGCTGTGTTGACTTGCAGTAGTAAGTAACTGAGAGCATAAAATAAACCTGACTGTATGAAGTCAATTTAAGTGATGAGAACATTTAA CTTTGGTGACTAAAGTCAGAATATCTTCTCACTTCACTTAAGGGATCTTCCAGAAGATATCTAAAAGTCTGTAATAAGCTTAGAAGTTCA GATAAATCTAGGCAGGATACTGCATTTTTGTGGTTTTAAAAAAGTCCTTAGGACAGACTGAATTATCATAACTTATGGCATCAGGAGGAA ACTTTAAAATATCAAGGAATCACTCAGTCACCCTCCTGTTTTGTTGAAGGATCAACCCCAAATTCTGGGTATTTGAGTACATGTGAATCA TGGATTTGGTATTCAACTTTTTCCCTGGATGCTTTGGAATCGTGTCTTCCATGCTCCACTGGGTTCAATTTAAAATAGGAGAGGCTTTCT CTTCTGAAAGATCCATTTTAGGTCTTTTTCAAGAATAGTGAACACATTTTTTAACAAAATAAGTTGTAATTTTAAAAGGAAAGTTTTGCC TATTTTATTAAGATGGAAATTTCTTTTTAGGCTAATTTGAAATCCAACTGAAGCTTTTTAACCAATATTTTAAATTTGAACCACTAGAGT TTTTTATGATGCAAATGATTATGTTGTCTGAAAGGTGTGGTTTTATTGAATGTCTATTTGAGTATCATTTAAAAAGTATTTGCCTTTTAC TGTCATCATTTCTCTTGTTTTATTATTATTATCAATGTTTATCTATTTTTCAATTAATTTAATACAGTTTCTAATGTGAAAGACATTTTT CTGGAACCCGTTTTCCCCTTAAACACTAAAGAGACCTCAAGTGAAAGCATATTGCTTAGTAGGAAGGTAGAAAATGTTAATCCCTGCGAT TCTTTGAGTTTTAATGACAGGGTCATTTTCAGTAAAGGAAATGCTCACCAACACATAGTCACCAACTATTAAAGGAATCATGTGATTGGA TTTTCCCCTGTATACATGTACCCTTGGTCATAATCCCACTATTTCATACATATTTATGCATTGCTAGATTTTCCTAGGACTCCAATAGCA TGCTTTCCAAGTGTTATTATTCCCTTAATGTTAAAGAAAAAAATCAATATATTGAATTCTTTAATTAAATAGGTAAGCAGTATTAAATCA TCCACAGAGATAAACAATCTCTTGAAACTCTTTTGAAAGAGAAAAGTGTTTGTTCACTTTCATTGCCTTCATTAAGATCTCCAAATACTC AGAGACTAAGCAGGCTATTCTCATCTCTTTGAGTTTCCTGACAGAACTAAAGGAAGGAATCACTCTTCAAAAGATGGATCTCACTTCACT CTGAAAATGTGCCTTTTTTTAATTGGGTGTTTAGCATAAAAATCACTATTGGGGATCTTACAGATGTCTGTTGTAGATCTATTACAATGA GGTGACTTAGACATTGGGCTTTACCATATTAGAGAATTACTTAAGCCATTGTCCTTCAAATGTTGGGCTTGGAGACAGAAGTACCTTGGA CTGAATTGCTTTCAAGTCTCTAGAATCACTGACAGCACATAGCTTCTATGAGGAGTTATATATGAAATACCACTTGTGTCCCTCCTCAAG TTCTCTGACCACCTTCACATCCTGCGGCCACCAACACTGTATGGATACAATCTGGCCTCTCAGCTCTGCTCACTTTCACTTTCTGTTCTG GGGATTCTCTGATACTAATTTTGGCTACTTGGTAGAACCAAGAGACAAATCGCTTACATGCTGCAAACCGATGTGAAGGTGTTACTAACC CGCTAAAACACAATTAATGAAAGACTGTAGCAGGTAACTGATCTTTCCCTCAGATATTCTACATGGTCCATGGAAGACTCTGTGGGCCGC AGAAGCCCATAGCTGCATACCCTTCTATTTTCCTCTTCCCCATTTCACTCTTTTAAGCTCCCTACTCCTATTCCCTATGATCACTTTCCA AAATAAACGGCAGGTGTGCTAGCTGTTGTCTTAGACTCTGCTTTCTGGAAACTATTTTTCCCCTCCACAAGAAATTATCACTGTGAATAT |
Top |
FusionGenePPI for TGFBRAP1_DPP10 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TGFBRAP1 | ALOX5, SMAD4, UVRAG, VPS41, NRBF2, VPS11, ACVR1, TGFBR1, TGFBR2, VPS18, VPS16, VPS8, VPS33A, ISOC2, C15orf27, ARFGAP1, C7orf60, CROCC, TRIM25 | DPP10 | KCND3, DPP10, KCND2, BAG3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TGFBRAP1_DPP10 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TGFBRAP1_DPP10 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | DPP10 | C0023903 | Liver neoplasms | 1 | CTD_human |
| Tgene | DPP10 | C0032927 | Precancerous Conditions | 1 | CTD_human |
| Tgene | DPP10 | C1510586 | Autism Spectrum Disorders | 1 | CTD_human |
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