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Fusion gene ID: 37914 |
FusionGeneSummary for TGFBR3_NRD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TGFBR3_NRD1 | Fusion gene ID: 37914 | Hgene | Tgene | Gene symbol | TGFBR3 | NRD1 | Gene ID | 7049 | 4898 |
| Gene name | transforming growth factor beta receptor 3 | nardilysin convertase | |
| Synonyms | BGCAN|betaglycan | NRD1|hNRD1|hNRD2 | |
| Cytomap | 1p22.1 | 1p32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transforming growth factor beta receptor type 3TGF-beta receptor type 3TGF-beta receptor type IIITGFR-3betaglycan proteoglycantransforming growth factor beta receptor III | nardilysinNRD convertasenardilysin (N-arginine dibasic convertase) | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q03167 | ||
| Ensembl transtripts involved in fusion gene | ENST00000212355, ENST00000370399, ENST00000525962, ENST00000468996, | ENST00000354831, ENST00000352171, ENST00000485608, ENST00000539524, ENST00000544028, | |
| Fusion gene scores | * DoF score | 6 X 5 X 4=120 | 4 X 3 X 3=36 |
| # samples | 7 | 4 | |
| ** MAII score | log2(7/120*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TGFBR3 [Title/Abstract] AND NRD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TGFBR3 | GO:0001837 | epithelial to mesenchymal transition | 18184661 |
| Hgene | TGFBR3 | GO:0007179 | transforming growth factor beta receptor signaling pathway | 12958365 |
| Hgene | TGFBR3 | GO:0030509 | BMP signaling pathway | 18184661 |
| Hgene | TGFBR3 | GO:0032354 | response to follicle-stimulating hormone | 14557487 |
| Hgene | TGFBR3 | GO:0034695 | response to prostaglandin E | 14557487 |
| Hgene | TGFBR3 | GO:0034699 | response to luteinizing hormone | 14557487 |
| Hgene | TGFBR3 | GO:0051271 | negative regulation of cellular component movement | 17999987 |
| Hgene | TGFBR3 | GO:0060317 | cardiac epithelial to mesenchymal transition | 18184661 |
| Tgene | NRD1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis | 18355445 |
| Tgene | NRD1 | GO:0052548 | regulation of endopeptidase activity | 18355445 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-EB-A82C-01A | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000212355 | ENST00000354831 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| In-frame | ENST00000212355 | ENST00000352171 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-intron | ENST00000212355 | ENST00000485608 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-5UTR | ENST00000212355 | ENST00000539524 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-5UTR | ENST00000212355 | ENST00000544028 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| In-frame | ENST00000370399 | ENST00000354831 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| In-frame | ENST00000370399 | ENST00000352171 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-intron | ENST00000370399 | ENST00000485608 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-5UTR | ENST00000370399 | ENST00000539524 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-5UTR | ENST00000370399 | ENST00000544028 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| Frame-shift | ENST00000525962 | ENST00000354831 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| Frame-shift | ENST00000525962 | ENST00000352171 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-intron | ENST00000525962 | ENST00000485608 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-5UTR | ENST00000525962 | ENST00000539524 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| 5CDS-5UTR | ENST00000525962 | ENST00000544028 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| intron-3CDS | ENST00000468996 | ENST00000354831 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| intron-3CDS | ENST00000468996 | ENST00000352171 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| intron-intron | ENST00000468996 | ENST00000485608 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| intron-5UTR | ENST00000468996 | ENST00000539524 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
| intron-5UTR | ENST00000468996 | ENST00000544028 | TGFBR3 | chr1 | 92327028 | - | NRD1 | chr1 | 52306186 | - |
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FusionProtFeatures for TGFBR3_NRD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TGFBR3 | NRD1 |
| Binds to TGF-beta. Could be involved in capturing andretaining TGF-beta for presentation to the signaling receptors. | Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >NRD1 | chr1:92327028 | chr1:52306186 | ENST00000352171 | - | 0 | 31 | 142_200 | 113 | 1152 | Compositional bias | Note=Asp/Glu-rich (highly acidic) |
| Tgene | >NRD1 | chr1:92327028 | chr1:52306186 | ENST00000352171 | - | 0 | 31 | 144_153 | 113 | 1152 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000212355 | - | 2 | 17 | 455_730 | 20 | 852 | Domain | ZP |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000370399 | - | 3 | 18 | 455_730 | 20 | 851 | Domain | ZP |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000525962 | - | 1 | 16 | 455_730 | 20 | 852 | Domain | ZP |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000212355 | - | 2 | 17 | 21_787 | 20 | 852 | Topological domain | Extracellular |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000212355 | - | 2 | 17 | 810_851 | 20 | 852 | Topological domain | Cytoplasmic |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000370399 | - | 3 | 18 | 21_787 | 20 | 851 | Topological domain | Extracellular |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000370399 | - | 3 | 18 | 810_851 | 20 | 851 | Topological domain | Cytoplasmic |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000525962 | - | 1 | 16 | 21_787 | 20 | 852 | Topological domain | Extracellular |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000525962 | - | 1 | 16 | 810_851 | 20 | 852 | Topological domain | Cytoplasmic |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000212355 | - | 2 | 17 | 788_809 | 20 | 852 | Transmembrane | Helical |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000370399 | - | 3 | 18 | 788_809 | 20 | 851 | Transmembrane | Helical |
| Hgene | >TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000525962 | - | 1 | 16 | 788_809 | 20 | 852 | Transmembrane | Helical |
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FusionGeneSequence for TGFBR3_NRD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TGFBR3_ENST00000212355_chr1_92327028_-_NRD1_ENST00000354831_chr1_52306186_-_1126aa MTSHYVIAIFALMSSCLATADTSNYRMACRHFXFQTXVIWKVKQEIQQMMKKKRRWRKKKKMMMKILELKXKMTMKRVLMMKMSLMMNMM MILILRIMNWKNXKREQKLEKKLLKNSNCRACFCCGQSXLIDCGLSQLIQKCLQPCWSRQEIFMGXLELKAGLHLFSIWQDGKRRSSRVK LTQFCLQRLFVLELGVSLIQMTCRGWHTFWSTWYSWVVXNIQMRMDLMPSXRSMGVVIMPQLIVNALSFSLMSRGSTSRKLLIDGRSSSS THXXSEMQLTVKLKLLIVNINLQGLLMQTERKCCLEALLDLDILWENFFGEMLRRSSMSQERIILIHMLDXENSGCVTTLLITXLXWFNP KKHWILWKSGXLKSSLRYQTMGYPDQTLAIXRIHLTHQHLTNFIELFQSEKFMLXPSHGHFLLNSNITGXSHFIIYPGWLDMKAKAAFFL SLGKNAGLLHCLVEMVRQDLSKILLIQCSAFLLHXLMRVMNIFMRLLTLSFSIXKCCRSXAQKKEFLKRFGKLRIMNFITKNRQIQLSMW KTCVRTCSCTHCRTFSLEISFFLNTSQKSLVKPXISXFLKKQILFYCLVLMRENVTSRRNGLELNIVXKILKTLGLNCGIVISNXIQIFI FQLKTSTXPRTLRXRLSIARKQNTQLKLXILHKVACGIRKTTNSKSPKHIYVSIXFHRXYRNLQQMWSSLISLSISLRITLRNQLMKQMW HSWSINWXLENMVXLFEXKDLTTNYLYCFSSLLTTXLSSIPHQLSLQXXLSSXRRPTLTSSSSPRLWPKMYGFXSWNMPVGLXLTSTRLX WTAFPLSLCXASSKNSNPSSLWRAWYKGMSQAQNLWISXNMLLTNXTSSLWSRRCLCSSRWXSCPVATIYAKXKLXTRVMPTLKSLCTTS QVPGVXENIRLWSCLXCTWKNLVLTSFEPSRPLGTMSTLPVGTHPGFXDFLSLWGLRQPNTILKLLIRRXKSFFLALRRRLRTSLKRHST PRSQLSSSXRSVRIPTLGRRWIGTGMKWLHSSTSLTALPTRLKHXSHSQNQTWSTGSRPIEGQEVKCSAFMLLDMGSMNWKRMVPLLVRI >In-frame_TGFBR3_ENST00000212355_chr1_92327028_-_NRD1_ENST00000352171_chr1_52306186_-_1058aa MTSHYVIAIFALMSSCLATADTSNYRMACRHFXFQTXVIWKVKQEIQQMMKKKRRWRKKKKMMMKILELKXKMTMKRVLMMKMSLMMNMM MILILRIMNWKNXKREQKLEKKLLKNSLQRLFVLELGVSLIQMTCRGWHTFWSTWYSWVVXNIQMRMDLMPSXRSMGVVIMPQLIVNALS FSLMSRGSTSRKLLIDGRSSSSTHXXSEMQLTVKLKLLIVNINLQGLLMQTERKCCLEALLDLDILWENFFGEMLRRSSMSQERIILIHM LDXENSGCVTTLLITXLXWFNPKKHWILWKSGXLKSSLRYQTMGYPDQTLAIXRIHLTHQHLTNFIELFQSEKFMLXPSHGHFLLNSNIT GXSHFIIYPGWLDMKAKAAFFLSLGKNAGLLHCLVEMVRQDLSKILLIQCSAFLLHXLMRVMNIFMRLLTLSFSIXKCCRSXAQKKEFLK RFGKLRIMNFITKNRQIQLSMWKTCVRTCSCTHCRTFSLEISFFLNTSQKSLVKPXISXFLKKQILFYCLVLMRENVTSRRNGLELNIVX KILKTLGLNCGIVISNXIQIFIFQLKTSTXPRTLRXRLSIARKQNTQLKLXILHKVACGIRKTTNSKSPKHIYVSIXFHRXYRNLQQMWS SLISLSISLRITLRNQLMKQMWHSWSINWXLENMVXLFEXKDLTTNYLYCFSSLLTTXLSSIPHQLSLQXXLSSXRRPTLTSSSSPRLWP KMYGFXSWNMPVGLXLTSTRLXWTAFPLSLCXASSKNSNPSSLWRAWYKGMSQAQNLWISXNMLLTNXTSSLWSRRCLCSSRWXSCPVAT IYAKXKLXTRVMPTLKSLCTTSQVPGVXENIRLWSCLXCTWKNLVLTSFEPSRPLGTMSTLPVGTHPGFXDFLSLWGLRQPNTILKLLIR RXKSFFLALRRRLRTSLKRHSTPRSQLSSSXRSVRIPTLGRRWIGTGMKWLHSSTSLTALPTRLKHXSHSQNQTWSTGSRPIEGQEVKCS >In-frame_TGFBR3_ENST00000370399_chr1_92327028_-_NRD1_ENST00000354831_chr1_52306186_-_1126aa MTSHYVIAIFALMSSCLATADTSNYRMACRHFXFQTXVIWKVKQEIQQMMKKKRRWRKKKKMMMKILELKXKMTMKRVLMMKMSLMMNMM MILILRIMNWKNXKREQKLEKKLLKNSNCRACFCCGQSXLIDCGLSQLIQKCLQPCWSRQEIFMGXLELKAGLHLFSIWQDGKRRSSRVK LTQFCLQRLFVLELGVSLIQMTCRGWHTFWSTWYSWVVXNIQMRMDLMPSXRSMGVVIMPQLIVNALSFSLMSRGSTSRKLLIDGRSSSS THXXSEMQLTVKLKLLIVNINLQGLLMQTERKCCLEALLDLDILWENFFGEMLRRSSMSQERIILIHMLDXENSGCVTTLLITXLXWFNP KKHWILWKSGXLKSSLRYQTMGYPDQTLAIXRIHLTHQHLTNFIELFQSEKFMLXPSHGHFLLNSNITGXSHFIIYPGWLDMKAKAAFFL SLGKNAGLLHCLVEMVRQDLSKILLIQCSAFLLHXLMRVMNIFMRLLTLSFSIXKCCRSXAQKKEFLKRFGKLRIMNFITKNRQIQLSMW KTCVRTCSCTHCRTFSLEISFFLNTSQKSLVKPXISXFLKKQILFYCLVLMRENVTSRRNGLELNIVXKILKTLGLNCGIVISNXIQIFI FQLKTSTXPRTLRXRLSIARKQNTQLKLXILHKVACGIRKTTNSKSPKHIYVSIXFHRXYRNLQQMWSSLISLSISLRITLRNQLMKQMW HSWSINWXLENMVXLFEXKDLTTNYLYCFSSLLTTXLSSIPHQLSLQXXLSSXRRPTLTSSSSPRLWPKMYGFXSWNMPVGLXLTSTRLX WTAFPLSLCXASSKNSNPSSLWRAWYKGMSQAQNLWISXNMLLTNXTSSLWSRRCLCSSRWXSCPVATIYAKXKLXTRVMPTLKSLCTTS QVPGVXENIRLWSCLXCTWKNLVLTSFEPSRPLGTMSTLPVGTHPGFXDFLSLWGLRQPNTILKLLIRRXKSFFLALRRRLRTSLKRHST PRSQLSSSXRSVRIPTLGRRWIGTGMKWLHSSTSLTALPTRLKHXSHSQNQTWSTGSRPIEGQEVKCSAFMLLDMGSMNWKRMVPLLVRI >In-frame_TGFBR3_ENST00000370399_chr1_92327028_-_NRD1_ENST00000352171_chr1_52306186_-_1058aa MTSHYVIAIFALMSSCLATADTSNYRMACRHFXFQTXVIWKVKQEIQQMMKKKRRWRKKKKMMMKILELKXKMTMKRVLMMKMSLMMNMM MILILRIMNWKNXKREQKLEKKLLKNSLQRLFVLELGVSLIQMTCRGWHTFWSTWYSWVVXNIQMRMDLMPSXRSMGVVIMPQLIVNALS FSLMSRGSTSRKLLIDGRSSSSTHXXSEMQLTVKLKLLIVNINLQGLLMQTERKCCLEALLDLDILWENFFGEMLRRSSMSQERIILIHM LDXENSGCVTTLLITXLXWFNPKKHWILWKSGXLKSSLRYQTMGYPDQTLAIXRIHLTHQHLTNFIELFQSEKFMLXPSHGHFLLNSNIT GXSHFIIYPGWLDMKAKAAFFLSLGKNAGLLHCLVEMVRQDLSKILLIQCSAFLLHXLMRVMNIFMRLLTLSFSIXKCCRSXAQKKEFLK RFGKLRIMNFITKNRQIQLSMWKTCVRTCSCTHCRTFSLEISFFLNTSQKSLVKPXISXFLKKQILFYCLVLMRENVTSRRNGLELNIVX KILKTLGLNCGIVISNXIQIFIFQLKTSTXPRTLRXRLSIARKQNTQLKLXILHKVACGIRKTTNSKSPKHIYVSIXFHRXYRNLQQMWS SLISLSISLRITLRNQLMKQMWHSWSINWXLENMVXLFEXKDLTTNYLYCFSSLLTTXLSSIPHQLSLQXXLSSXRRPTLTSSSSPRLWP KMYGFXSWNMPVGLXLTSTRLXWTAFPLSLCXASSKNSNPSSLWRAWYKGMSQAQNLWISXNMLLTNXTSSLWSRRCLCSSRWXSCPVAT IYAKXKLXTRVMPTLKSLCTTSQVPGVXENIRLWSCLXCTWKNLVLTSFEPSRPLGTMSTLPVGTHPGFXDFLSLWGLRQPNTILKLLIR RXKSFFLALRRRLRTSLKRHSTPRSQLSSSXRSVRIPTLGRRWIGTGMKWLHSSTSLTALPTRLKHXSHSQNQTWSTGSRPIEGQEVKCS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TGFBR3_ENST00000212355_chr1_92327028_-_NRD1_ENST00000354831_chr1_52306186_-_3380nt ATGACTTCCCATTATGTGATTGCCATCTTTGCCCTGATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTACAGAATGGCTTGCAGG CACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAGGTGGAGGAAGAAGAAG AAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTTGATGATGAACATGATG ATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAAAAACAGCAATTGCAGA GCCTGTTTTTGCTGTGGTCAAAGCTGACTGATAGACTGTGGTTTAAGTCAACTTATTCAAAAATGTCTTCAACCCTGCTGGTCGAGACAA GAAATCTTTATGGGGTAGTTGGAGCTGAAAGCAGGTCTGCACCTGTTCAGCATTTGGCAGGATGGCAAGCGGAGGAGCAGCAGGGTGAAA CTGACACAGTTCTGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGG AGCACATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCT CAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCC ACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAA AGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAA GAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCA AAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATT TAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCAC TTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTT TCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCA TTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAG GCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGG AAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTG GTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAAT GGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATC TTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATA CTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATAC AGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGG CACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGC TCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCC TCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGA TGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCA CAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGG TGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGT CAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGC AGACCCTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAAT ACAATTCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACA CCCAGGTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACAC AGCAGTACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATA GAGGGCCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATT CAAATTCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGG >In-frame_TGFBR3_ENST00000212355_chr1_92327028_-_NRD1_ENST00000352171_chr1_52306186_-_3176nt ATGACTTCCCATTATGTGATTGCCATCTTTGCCCTGATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTACAGAATGGCTTGCAGG CACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAGGTGGAGGAAGAAGAAG AAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTTGATGATGAACATGATG ATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAAAAACAGTCTGCAGCGG CTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTT TGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCT TTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAA TTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTG CTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATG CTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAA AGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAG CATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACA GGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTC TTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGG GTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAG AGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGC TGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTC CTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAG AAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAG CCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATA AGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCC TCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAG CTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGT TCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCA AAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTC TGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCC TGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACC ATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAAT ATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACC CTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGA AGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGC TGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTG CCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCA GCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGC AGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTCACAACAACACTCAACCTTC >In-frame_TGFBR3_ENST00000370399_chr1_92327028_-_NRD1_ENST00000354831_chr1_52306186_-_3380nt ATGACTTCCCATTATGTGATTGCCATCTTTGCCCTGATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTACAGAATGGCTTGCAGG CACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAGGTGGAGGAAGAAGAAG AAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTTGATGATGAACATGATG ATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAAAAACAGCAATTGCAGA GCCTGTTTTTGCTGTGGTCAAAGCTGACTGATAGACTGTGGTTTAAGTCAACTTATTCAAAAATGTCTTCAACCCTGCTGGTCGAGACAA GAAATCTTTATGGGGTAGTTGGAGCTGAAAGCAGGTCTGCACCTGTTCAGCATTTGGCAGGATGGCAAGCGGAGGAGCAGCAGGGTGAAA CTGACACAGTTCTGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGG AGCACATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCT CAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCC ACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAA AGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAA GAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCA AAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATT TAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCAC TTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTT TCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCA TTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAG GCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGG AAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTG GTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAAT GGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATC TTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATA CTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATAC AGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGG CACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGC TCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCC TCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGA TGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCA CAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGG TGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGT CAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGC AGACCCTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAAT ACAATTCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACA CCCAGGTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACAC AGCAGTACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATA GAGGGCCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATT CAAATTCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGG >In-frame_TGFBR3_ENST00000370399_chr1_92327028_-_NRD1_ENST00000352171_chr1_52306186_-_3176nt ATGACTTCCCATTATGTGATTGCCATCTTTGCCCTGATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTACAGAATGGCTTGCAGG CACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAGGTGGAGGAAGAAGAAG AAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTTGATGATGAACATGATG ATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAAAAACAGTCTGCAGCGG CTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTT TGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCT TTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAA TTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTG CTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATG CTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAA AGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAG CATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACA GGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTC TTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGG GTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAG AGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGC TGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTC CTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAG AAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAG CCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATA AGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCC TCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAG CTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGT TCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCA AAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTC TGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCC TGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACC ATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAAT ATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACC CTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGA AGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGC TGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTG CCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCA GCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGC AGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTCACAACAACACTCAACCTTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TGFBR3_ENST00000212355_chr1_92327028_-_NRD1_ENST00000354831_chr1_52306186_-_3891nt GATTGCTGTGGCGTCCTGCCCGTCCCCGCCCGCGTGTGTGCGAGGGAGGGCGAGTGCGCCGGGTCGGCCTGATGGGGGTAATCGAGGGTT TCGGGGACGCCGAGCGGCACTTTCCTCTTCCCAGCGAGTGAAGGAGGGCAGTCGGCGGCTCTCGCGCCCCGGCCACTTTCCCTGCGCGAT TCCCGGAGCTCCCTGCAGGAGGTGAGAGTCCCCAGCGGGTCCGGATGGCGTAGTTTTGCCGCGGCGCAGCAGCTGCCGGAGCTCGCCGCC GCCGAGCGCTGGGCGGGGAAACTTGCCGCCGCTTTCCTCCAACTTGCTGCGGGTGGATCTCCGCTGGACACACCGCCTCCGAGGCAGTTT GAAAATTGCAAGGAGGGACTTTAAGACTACTTCTGATTTGCAAAGATTGTCTGTGCTCTGAGCAGGCTGAAGTGACTGGACGAGACGCAC TGTTGGAGAAATAAAAATGACTTCCCATTATGTGATTGCCATCTTTGCCCTGATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTA CAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAG GTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTT GATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAA AAACAGCAATTGCAGAGCCTGTTTTTGCTGTGGTCAAAGCTGACTGATAGACTGTGGTTTAAGTCAACTTATTCAAAAATGTCTTCAACC CTGCTGGTCGAGACAAGAAATCTTTATGGGGTAGTTGGAGCTGAAAGCAGGTCTGCACCTGTTCAGCATTTGGCAGGATGGCAAGCGGAG GAGCAGCAGGGTGAAACTGACACAGTTCTGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGG CTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGG GGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGG GCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCT TCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACG CTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACT TTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGA CCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTG ACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAA GGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACT TATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAA ATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGAT CCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATAC AAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGT GACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTA AATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCA GTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTA ATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCT TATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTA CCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAG ACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGAC AAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTG GTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATG CCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTC ACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGAC TTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGG ACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACT GAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGG AATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAAC TGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACC CCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCC ATTACTGATATCAGGGCTTTCACAACAACACTCAACCTTCTCCCCTACCATAAAATAGTCAAATAAATAAACTGCAGTCACGTTGGCCTG >In-frame_TGFBR3_ENST00000212355_chr1_92327028_-_NRD1_ENST00000352171_chr1_52306186_-_3687nt GATTGCTGTGGCGTCCTGCCCGTCCCCGCCCGCGTGTGTGCGAGGGAGGGCGAGTGCGCCGGGTCGGCCTGATGGGGGTAATCGAGGGTT TCGGGGACGCCGAGCGGCACTTTCCTCTTCCCAGCGAGTGAAGGAGGGCAGTCGGCGGCTCTCGCGCCCCGGCCACTTTCCCTGCGCGAT TCCCGGAGCTCCCTGCAGGAGGTGAGAGTCCCCAGCGGGTCCGGATGGCGTAGTTTTGCCGCGGCGCAGCAGCTGCCGGAGCTCGCCGCC GCCGAGCGCTGGGCGGGGAAACTTGCCGCCGCTTTCCTCCAACTTGCTGCGGGTGGATCTCCGCTGGACACACCGCCTCCGAGGCAGTTT GAAAATTGCAAGGAGGGACTTTAAGACTACTTCTGATTTGCAAAGATTGTCTGTGCTCTGAGCAGGCTGAAGTGACTGGACGAGACGCAC TGTTGGAGAAATAAAAATGACTTCCCATTATGTGATTGCCATCTTTGCCCTGATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTA CAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTAAAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAG GTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAGATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTT GATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAATTAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAA AAACAGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGGAGCACATG GTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGAT TGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTA ATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATG TTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAAT AATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACA CTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGAT CCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCT CAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGG AAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATT ACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAA AAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATG TGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCC TTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGA ACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCT GAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAA GGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCT GCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTG GAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATT GACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAG CCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGC CTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACA GAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAG CTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACC AGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTT GGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCT GAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTC ACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTAC CTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCA GGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCT TCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTCACA >In-frame_TGFBR3_ENST00000370399_chr1_92327028_-_NRD1_ENST00000354831_chr1_52306186_-_4109nt AAGAATCTTGTTTTTTTGAGACGGAGTCTCACCCTGTCGCCCGGGCTGGAGTGCAGTGGCGCGATCGCAACCTCCGCTTCCCGGGTTCAA GGGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCACGCCACTACACCCGGCCAATTTTTGTATTTATTTATTTTATTT TATTTTATTTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGAACAGTCTCGATCTCCTAACCTCGTGATCCACCCGCCTCGGGCTCC CAAAGTGTTGAGATTACAGGCGTGAGCCACCGCGCCCGTCCAGAATTATCTTTAAAATTTATTTCTTTAAGATTTGTAGCTACTAAGAAA GAAAGGAGCTTTTTTTCCTTGGGCCTTCAAACTGAAAGAACCGCATGAGCCTGAAGCTGCGCATGGTCTTAACATCAGGCTGTGCAGGAA GAAGCTATCTGCAGATGGATGCCAGCACACACAAGGAAGCAGAGCTCTGGCAACATTGAGTCAAAGCAAGGACACAACATCAGAGGGACG GCAGAGAATCCTTGTGTGTAGATCTTTGGTGGCAGTTTGAAAATTGCAAGGAGGGACTTTAAGACTACTTCTGATTTGCAAAGATTGTCT GTGCTCTGAGCAGGCTGAAGTGACTGGACGAGACGCACTGTTGGAGAAATAAAAATGACTTCCCATTATGTGATTGCCATCTTTGCCCTG ATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTA AAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAG ATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAAT TAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAAAAACAGCAATTGCAGAGCCTGTTTTTGCTGTGGTCAAAGCTGACTGATAGAC TGTGGTTTAAGTCAACTTATTCAAAAATGTCTTCAACCCTGCTGGTCGAGACAAGAAATCTTTATGGGGTAGTTGGAGCTGAAAGCAGGT CTGCACCTGTTCAGCATTTGGCAGGATGGCAAGCGGAGGAGCAGCAGGGTGAAACTGACACAGTTCTGTCTGCAGCGGCTCTTTGTGTTG GAGTTGGGAGTTTCGCTGATCCAGATGACCTGCCGGGGCTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTTTGAAATATCCAG ATGAGAATGGATTTGATGCCTTCCTGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATG TCCAGAGGAAGTACTTCAAGGAAGCTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAG TTGAAGCTGTTGATAGTGAATATCAACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGAC ATCCTATGGGAAAATTTTTTTGGGGAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAG AATTCTGGATGCGTTACTACTCTTCTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTG AAATCTTCTCTCAGATACCAAACAATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAAC TTTATAGAGTTGTTCCAATCAGAAAAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCAC TTCATTATATATCCTGGCTGGTTGGACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTG GTGGAAATGGTGAGACAGGATTTGAGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATT TTTATGAGGTTGCTTACACTGTCTTTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAA TTGAGGATAATGAATTTCATTACCAAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGC AGGACATTCTCACTGGAGATCAGCTTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAA ATCTTGTTTTACTGTCTGGTGCTAATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAA ACTCTTGGGCTGAACTGTGGAATAGTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTA CGTTGAAGGCTTTCGATTGCCCGGAAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACA AATTCAAAATCCCCAAAGCATATATACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCT TTGTCAATATCCTTACGCATAACCTTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATG GTTTAATTATTCGAGTGAAAGGATTTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACAC CAGCTGTCTTTACAATGATAACTGAGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGC TTTTAATCTTGGAATATGCCCGTTGGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCG TCAAAGAATTCAAATCCCAGCTCTTTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTG TTGACAAACTAAACTTCAAGCCTCTGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAG TGAAAGCTCTGAACAAGGGTGATGCCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATACGCTTATGG AGCTGCTTGTGATGCACATGGAAGAACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACCCTACCTGTAGGA ACACATCCGGGATTCTAGGATTTTCTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGAAGATAGAAGAGT TTCTTTCTAGCTTTGAGGAGAAGATTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGCTGAAGGAGTGTG AGGATACCCACCTTGGGGAGGAGGTGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTGCCCACGAGATTG AAGCACTGAAGTCATTCTCAAAATCAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCAGCGTTCATGTTG TTGGATATGGGAAGTATGAACTGGAAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGCAGCTGACCTACC TGCCAACCTCTCCTCTGCTGGCAGATTGTATCATCCCCATTACTGATATCAGGGCTTTCACAACAACACTCAACCTTCTCCCCTACCATA >In-frame_TGFBR3_ENST00000370399_chr1_92327028_-_NRD1_ENST00000352171_chr1_52306186_-_3905nt AAGAATCTTGTTTTTTTGAGACGGAGTCTCACCCTGTCGCCCGGGCTGGAGTGCAGTGGCGCGATCGCAACCTCCGCTTCCCGGGTTCAA GGGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCACGCCACTACACCCGGCCAATTTTTGTATTTATTTATTTTATTT TATTTTATTTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGAACAGTCTCGATCTCCTAACCTCGTGATCCACCCGCCTCGGGCTCC CAAAGTGTTGAGATTACAGGCGTGAGCCACCGCGCCCGTCCAGAATTATCTTTAAAATTTATTTCTTTAAGATTTGTAGCTACTAAGAAA GAAAGGAGCTTTTTTTCCTTGGGCCTTCAAACTGAAAGAACCGCATGAGCCTGAAGCTGCGCATGGTCTTAACATCAGGCTGTGCAGGAA GAAGCTATCTGCAGATGGATGCCAGCACACACAAGGAAGCAGAGCTCTGGCAACATTGAGTCAAAGCAAGGACACAACATCAGAGGGACG GCAGAGAATCCTTGTGTGTAGATCTTTGGTGGCAGTTTGAAAATTGCAAGGAGGGACTTTAAGACTACTTCTGATTTGCAAAGATTGTCT GTGCTCTGAGCAGGCTGAAGTGACTGGACGAGACGCACTGTTGGAGAAATAAAAATGACTTCCCATTATGTGATTGCCATCTTTGCCCTG ATGAGCTCCTGTTTAGCCACTGCAGATACATCAAATTACAGAATGGCTTGCAGGCACTTCTGATTTCAGACCTAAGTAATATGGAAGGTA AAACAGGAAATACAACAGATGATGAAGAAGAAGAGGAGGTGGAGGAAGAAGAAGAAGATGATGATGAAGATTCTGGAGCTGAAATAGAAG ATGACGATGAAGAGGGTTTTGATGATGAAGATGAGTTTGATGATGAACATGATGATGATCTTGATACTGAGGATAATGAATTGGAAGAAT TAGAAGAGAGAGCAGAAGCTAGAAAAAAAACTACTGAAAAACAGTCTGCAGCGGCTCTTTGTGTTGGAGTTGGGAGTTTCGCTGATCCAG ATGACCTGCCGGGGCTGGCACACTTTTTGGAGCACATGGTATTCATGGGTAGTTTGAAATATCCAGATGAGAATGGATTTGATGCCTTCC TGAAGAAGCATGGGGGTAGTGATAATGCCTCAACTGATTGTGAACGCACTGTCTTTCAGTTTGATGTCCAGAGGAAGTACTTCAAGGAAG CTCTTGATAGATGGGCGCAGTTCTTCATCCACCCACTAATGATCAGAGATGCAATTGACCGTGAAGTTGAAGCTGTTGATAGTGAATATC AACTTGCAAGGCCTTCTGATGCAAACAGAAAGGAAATGTTGTTTGGAAGCCTTGCTAGACCTGGACATCCTATGGGAAAATTTTTTTGGG GAAATGCTGAGACGCTCAAGCATGAGCCAAGAAAGAATAATATTGATACACATGCTAGATTGAGAGAATTCTGGATGCGTTACTACTCTT CTCATTACATGACTTTAGTGGTTCAATCCAAAGAAACACTGGATACTTTGGAAAAGTGGGTGACTGAAATCTTCTCTCAGATACCAAACA ATGGGTTACCCAGACCAAACTTTGGCCATTTAACGGATCCATTTGACACACCAGCATTTAACAAACTTTATAGAGTTGTTCCAATCAGAA AAATTCATGCTCTGACCATCACATGGGCACTTCCTCCTCAACAGCAACATTACAGGGTGAAGCCACTTCATTATATATCCTGGCTGGTTG GACATGAAGGCAAAGGCAGCATTCTTTCTTTCCTTAGGAAAAAATGCTGGGCTCTTGCACTGTTTGGTGGAAATGGTGAGACAGGATTTG AGCAAAATTCTACTTATTCAGTGTTCAGCATTTCTATTACATTGACTGATGAGGGTTATGAACATTTTTATGAGGTTGCTTACACTGTCT TTCAGTATTTAAAAATGCTGCAGAAGCTAGGCCCAGAAAAAAGAATTTTTGAAGAGATTCGGAAAATTGAGGATAATGAATTTCATTACC AAGAACAGACAGATCCAGTTGAGTATGTGGAAAACATGTGTGAGAACATGCAGCTGTACCCATTGCAGGACATTCTCACTGGAGATCAGC TTCTTTTTGAATACAAGCCAGAAGTCATTGGTGAAGCCTTGAATCAGCTAGTTCCTCAAAAAGCAAATCTTGTTTTACTGTCTGGTGCTA ATGAGGGAAAATGTGACCTCAAGGAGAAATGGTTTGGAACTCAATATAGTATAGAAGATATTGAAAACTCTTGGGCTGAACTGTGGAATA GTAATTTCGAATTAAATCCAGATCTTCATCTTCCAGCTGAAAACAAGTACATAGCCACGGACTTTACGTTGAAGGCTTTCGATTGCCCGG AAACAGAATACCCAGTTAAAATTGTGAATACTCCACAAGGTTGCCTGTGGTATAAGAAAGACAACAAATTCAAAATCCCCAAAGCATATA TACGTTTCCATCTAATTTCACCGTTGATACAGAAATCTGCAGCAAATGTGGTCCTCTTTGATATCTTTGTCAATATCCTTACGCATAACC TTGCGGAACCAGCTTATGAAGCAGATGTGGCACAGCTGGAGTATAAACTGGTAGCTGGAGAACATGGTTTAATTATTCGAGTGAAAGGAT TTAACCACAAACTACCTCTACTGTTTCAGCTCATTATTGACTACTTAGCTGAGTTCAATTCCACACCAGCTGTCTTTACAATGATAACTG AGCAGTTGAAGAAGACCTACTTTAACATCCTCATCAAGCCCGAGACTTTGGCCAAAGATGTACGGCTTTTAATCTTGGAATATGCCCGTT GGTCTATGATTGACAAGTACCAGGCTTTGATGGACGGCCTTTCCCTTGAGTCTCTGCTGAGCTTCGTCAAAGAATTCAAATCCCAGCTCT TTGTGGAGGGCCTGGTACAAGGGAATGTCACAAGCACAGAATCTATGGATTTCCTGAAATATGTTGTTGACAAACTAAACTTCAAGCCTC TGGAGCAGGAGATGCCTGTGCAGTTCCAGGTGGTAGAGCTGCCCAGTGGCCACCATCTATGCAAAGTGAAAGCTCTGAACAAGGGTGATG CCAACTCTGAAGTCACTGTGTACTACCAGTCAGGTACCAGGAGTCTAAGAGAATATACGCTTATGGAGCTGCTTGTGATGCACATGGAAG AACCTTGTTTTGACTTCCTTCGAACCAAGCAGACCCTTGGGTACCATGTCTACCCTACCTGTAGGAACACATCCGGGATTCTAGGATTTT CTGTCACTGTGGGGACTCAGGCAACCAAATACAATTCTGAAGTTGTTGATAAGAAGATAGAAGAGTTTCTTTCTAGCTTTGAGGAGAAGA TTGAGAACCTCACTGAAGAGGCATTCAACACCCAGGTCACAGCTCTCATCAAGCTGAAGGAGTGTGAGGATACCCACCTTGGGGAGGAGG TGGATAGGAACTGGAATGAAGTGGTTACACAGCAGTACCTCTTTGACCGCCTTGCCCACGAGATTGAAGCACTGAAGTCATTCTCAAAAT CAGACCTGGTCAACTGGTTCAAGGCCCATAGAGGGCCAGGAAGTAAAATGCTCAGCGTTCATGTTGTTGGATATGGGAAGTATGAACTGG AAGAGGATGGTACCCCTTCTAGTGAGGATTCAAATTCTTCTTGTGAAGTGATGCAGCTGACCTACCTGCCAACCTCTCCTCTGCTGGCAG ATTGTATCATCCCCATTACTGATATCAGGGCTTTCACAACAACACTCAACCTTCTCCCCTACCATAAAATAGTCAAATAAATAAACTGCA |
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FusionGenePPI for TGFBR3_NRD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TGFBR3 | TGFBR2, TGFB1, ELAVL1, NRP1, KLK11, ITM2B, ATP1B3, FGF1, GPR183, ATP1B4, PTCH1, SIAE, PIP5K1A, CAMKV, DEFA5, ST8SIA4, FAM19A4, DKKL1, CANT1, DEFA1 | NRD1 | HBEGF, BTRC, FBXW11, UIMC1, HIST2H3C, MAD1L1, COBLL1, NCOR1, UACA, IQGAP1, HDAC3, NCOR2, TBL1X, NRD1, MOB1A, STK3, MOB2, HSPB1, PNKP, DNAJC7, ELAC2, P3H1, SETSIP, MSH2, NSUN2, PDIA6, PFDN5, PPP1R12A, PPP2CA, PPP2R2A, PPP3CA, PUS1, XPO5, YARS, PFDN1, TSN, MOV10, NXF1, FMR1NB, ZNF707, LUC7L, SEPT1, KPNA3, NTRK1, ATM, LGALS3BP, PDGFRA, ERP44, PCDHB15, KIF7, CHCHD2, ATP5A1, APOOL, COQ7, COQ6, WBSCR16, LYRM4, C6orf203, CHCHD1, NME4, OCIAD1, ACP6, ADCK2, TRUB2, DHRS4, CISD3, OPA3, BOLA3, NLGN3, AURKAIP1, TMEM184A, DEF8, BATF3, METTL25, CDRT15, CLK3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000212355 | - | 2 | 17 | 737_751 | 20 | 852 | TGF-beta ligand |
| Hgene | TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000370399 | - | 3 | 18 | 737_751 | 20 | 851 | TGF-beta ligand |
| Hgene | TGFBR3 | chr1:92327028 | chr1:52306186 | ENST00000525962 | - | 1 | 16 | 737_751 | 20 | 852 | TGF-beta ligand |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TGFBR3_NRD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TGFBR3_NRD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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