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Fusion gene ID: 37746 |
FusionGeneSummary for TESC_ASAH1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TESC_ASAH1 | Fusion gene ID: 37746 | Hgene | Tgene | Gene symbol | TESC | ASAH1 | Gene ID | 54997 | 427 |
| Gene name | tescalcin | N-acylsphingosine amidohydrolase 1 | |
| Synonyms | CHP3|TSC | AC|ACDase|ASAH|PHP|PHP32|SMAPME | |
| Cytomap | 12q24.22 | 8p22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | calcineurin B homologous protein 3calcineurin-like EF hand protein 3 | acid ceramidaseN-acylsphingosine amidohydrolase (acid ceramidase) 1acid CDaseacylsphingosine deacylaseputative 32 kDa heart protein | |
| Modification date | 20180519 | 20180529 | |
| UniProtAcc | Q96BS2 | Q13510 | |
| Ensembl transtripts involved in fusion gene | ENST00000335209, ENST00000541210, ENST00000392545, ENST00000535198, | ENST00000262097, ENST00000381733, ENST00000417108, ENST00000520781, ENST00000314146, ENST00000520051, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 6 X 6 X 5=180 |
| # samples | 4 | 7 | |
| ** MAII score | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/180*10)=-1.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TESC [Title/Abstract] AND ASAH1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TESC | GO:0030854 | positive regulation of granulocyte differentiation | 20060826 |
| Hgene | TESC | GO:0032417 | positive regulation of sodium:proton antiporter activity | 18321853 |
| Hgene | TESC | GO:0050821 | protein stabilization | 18321853 |
| Hgene | TESC | GO:0051604 | protein maturation | 18321853 |
| Hgene | TESC | GO:0071300 | cellular response to retinoic acid | 20060826 |
| Hgene | TESC | GO:0072659 | protein localization to plasma membrane | 18321853 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-YL-A9WJ-01A | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000335209 | ENST00000262097 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| In-frame | ENST00000335209 | ENST00000381733 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000335209 | ENST00000417108 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000335209 | ENST00000520781 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000335209 | ENST00000314146 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000335209 | ENST00000520051 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| In-frame | ENST00000541210 | ENST00000262097 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| In-frame | ENST00000541210 | ENST00000381733 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000541210 | ENST00000417108 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000541210 | ENST00000520781 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000541210 | ENST00000314146 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000541210 | ENST00000520051 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| In-frame | ENST00000392545 | ENST00000262097 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| In-frame | ENST00000392545 | ENST00000381733 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000392545 | ENST00000417108 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000392545 | ENST00000520781 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000392545 | ENST00000314146 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| 5CDS-5UTR | ENST00000392545 | ENST00000520051 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| intron-3CDS | ENST00000535198 | ENST00000262097 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| intron-3CDS | ENST00000535198 | ENST00000381733 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| intron-5UTR | ENST00000535198 | ENST00000417108 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| intron-5UTR | ENST00000535198 | ENST00000520781 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| intron-5UTR | ENST00000535198 | ENST00000314146 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
| intron-5UTR | ENST00000535198 | ENST00000520051 | TESC | chr12 | 117537030 | - | ASAH1 | chr8 | 17933096 | - |
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FusionProtFeatures for TESC_ASAH1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TESC | ASAH1 |
| Functions as an integral cofactor in cell pH regulationby controlling plasma membrane-type Na(+)/H(+) exchange activity.Promotes the maturation, transport, cell surface stability andexchange activity of SLC9A1/NHE1 at the plasma membrane. Promotesthe induction of hematopoietic stem cell differentiation towardmegakaryocytic lineage. Essential for the coupling of ERK cascadeactivation with the expression of ETS family genes inmegakaryocytic differentiation. Also involved in granulocyticdifferentiation in a ERK-dependent manner. Inhibits thephosphatase activity of calcineurin. {ECO:0000269|PubMed:17717601,ECO:0000269|PubMed:18321853, ECO:0000269|PubMed:20060826}. | Hydrolyzes the sphingolipid ceramide into sphingosineand free fatty acid. {ECO:0000269|PubMed:7744740}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TESC | chr12:117537030 | chr8:17933096 | ENST00000335209 | - | 1 | 8 | 123_134 | 19 | 215 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | >TESC | chr12:117537030 | chr8:17933096 | ENST00000541210 | - | 1 | 7 | 123_134 | 19 | 188 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | >TESC | chr12:117537030 | chr8:17933096 | ENST00000335209 | - | 1 | 8 | 110_145 | 19 | 215 | Domain | EF-hand |
| Hgene | >TESC | chr12:117537030 | chr8:17933096 | ENST00000541210 | - | 1 | 7 | 110_145 | 19 | 188 | Domain | EF-hand |
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FusionGeneSequence for TESC_ASAH1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TESC_ENST00000335209_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_389aa MGAAHSASEEVRELEGKTGLDRGLQKINLSSFRTNVQRCSSMVHHKSXLTTLQKMAXIDAXQGTSAKGYSEFSEEYDKYIRAKWKNYAGG GXKIAWPTWQLSWPFXRGNEGYCRCYXYTFRRDYFIQYFLXIIYHLYFNSSRRQKRSSNTWEKHGFWSISWVEHKXXYLGHNXATKTFNS EFGFPKKQQNCLQGFKLCWLCGHVNRIQTRTVQSYTEXTFQYKWWLSGYSRMDSGKERCHVDRVPHXNSSGKXHKLXRSQEFIDQDQDIG PSLLYPGRQPVWGRLCDYTRQKGIIGCIXTRCXAGXMVCGTNKLXPLETSLLPXXSQNACKDVSEPHQPREYLIXNHVXCPVNKTCPQQA >In-frame_TESC_ENST00000335209_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_389aa MGAAHSASEEVRELEGKTGLDRGLQKINLSSFRTNVQRCSSMVHHKSXLTTLQKMAXIDAXQGTSAKGYSEFSEEYDKYIRAKWKNYAGG GXKIAWPTWQLSWPFXRGNEGYCRCYXYTFRRDYFIQYFLXIIYHLYFNSSRRQKRSSNTWEKHGFWSISWVEHKXXYLGHNXATKTFNS EFGFPKKQQNCLQGFKLCWLCGHVNRIQTRTVQSYTEXTFQYKWWLSGYSRMDSGKERCHVDRVPHXNSSGKXHKLXRSQEFIDQDQDIG PSLLYPGRQPVWGRLCDYTRQKGIIGCIXTRCXAGXMVCGTNKLXPLETSLLPXXSQNACKDVSEPHQPREYLIXNHVXCPVNKTCPQQA >In-frame_TESC_ENST00000541210_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_389aa MGAAHSASEEVRELEGKTGLDRGLQKINLSSFRTNVQRCSSMVHHKSXLTTLQKMAXIDAXQGTSAKGYSEFSEEYDKYIRAKWKNYAGG GXKIAWPTWQLSWPFXRGNEGYCRCYXYTFRRDYFIQYFLXIIYHLYFNSSRRQKRSSNTWEKHGFWSISWVEHKXXYLGHNXATKTFNS EFGFPKKQQNCLQGFKLCWLCGHVNRIQTRTVQSYTEXTFQYKWWLSGYSRMDSGKERCHVDRVPHXNSSGKXHKLXRSQEFIDQDQDIG PSLLYPGRQPVWGRLCDYTRQKGIIGCIXTRCXAGXMVCGTNKLXPLETSLLPXXSQNACKDVSEPHQPREYLIXNHVXCPVNKTCPQQA >In-frame_TESC_ENST00000541210_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_389aa MGAAHSASEEVRELEGKTGLDRGLQKINLSSFRTNVQRCSSMVHHKSXLTTLQKMAXIDAXQGTSAKGYSEFSEEYDKYIRAKWKNYAGG GXKIAWPTWQLSWPFXRGNEGYCRCYXYTFRRDYFIQYFLXIIYHLYFNSSRRQKRSSNTWEKHGFWSISWVEHKXXYLGHNXATKTFNS EFGFPKKQQNCLQGFKLCWLCGHVNRIQTRTVQSYTEXTFQYKWWLSGYSRMDSGKERCHVDRVPHXNSSGKXHKLXRSQEFIDQDQDIG PSLLYPGRQPVWGRLCDYTRQKGIIGCIXTRCXAGXMVCGTNKLXPLETSLLPXXSQNACKDVSEPHQPREYLIXNHVXCPVNKTCPQQA >In-frame_TESC_ENST00000392545_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_442aa MRPRSGPTRNPRLRAFAGVPTRGRTRGQSRRCAAEASAGPERDARPGAPAAGTMGAAHSASEEVRELEGKTGLDRGLQKINLSSFRTNVQ RCSSMVHHKSXLTTLQKMAXIDAXQGTSAKGYSEFSEEYDKYIRAKWKNYAGGGXKIAWPTWQLSWPFXRGNEGYCRCYXYTFRRDYFIQ YFLXIIYHLYFNSSRRQKRSSNTWEKHGFWSISWVEHKXXYLGHNXATKTFNSEFGFPKKQQNCLQGFKLCWLCGHVNRIQTRTVQSYTE XTFQYKWWLSGYSRMDSGKERCHVDRVPHXNSSGKXHKLXRSQEFIDQDQDIGPSLLYPGRQPVWGRLCDYTRQKGIIGCIXTRCXAGXM >In-frame_TESC_ENST00000392545_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_442aa MRPRSGPTRNPRLRAFAGVPTRGRTRGQSRRCAAEASAGPERDARPGAPAAGTMGAAHSASEEVRELEGKTGLDRGLQKINLSSFRTNVQ RCSSMVHHKSXLTTLQKMAXIDAXQGTSAKGYSEFSEEYDKYIRAKWKNYAGGGXKIAWPTWQLSWPFXRGNEGYCRCYXYTFRRDYFIQ YFLXIIYHLYFNSSRRQKRSSNTWEKHGFWSISWVEHKXXYLGHNXATKTFNSEFGFPKKQQNCLQGFKLCWLCGHVNRIQTRTVQSYTE XTFQYKWWLSGYSRMDSGKERCHVDRVPHXNSSGKXHKLXRSQEFIDQDQDIGPSLLYPGRQPVWGRLCDYTRQKGIIGCIXTRCXAGXM |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TESC_ENST00000335209_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_1168nt ATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCC TCCTTCAGGACCAACGTACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCT TGACAAGGCACCAGTGCTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGT GGATGAAAAATTGCCTGGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTT AGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACA TGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGT GAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGG ACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCAT GTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGC CCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACT CGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGC AAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCT >In-frame_TESC_ENST00000335209_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_1168nt ATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCC TCCTTCAGGACCAACGTACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCT TGACAAGGCACCAGTGCTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGT GGATGAAAAATTGCCTGGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTT AGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACA TGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGT GAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGG ACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCAT GTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGC CCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACT CGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGC AAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCT >In-frame_TESC_ENST00000541210_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_1168nt ATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCC TCCTTCAGGACCAACGTACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCT TGACAAGGCACCAGTGCTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGT GGATGAAAAATTGCCTGGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTT AGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACA TGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGT GAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGG ACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCAT GTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGC CCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACT CGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGC AAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCT >In-frame_TESC_ENST00000541210_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_1168nt ATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCC TCCTTCAGGACCAACGTACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCT TGACAAGGCACCAGTGCTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGT GGATGAAAAATTGCCTGGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTT AGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACA TGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGT GAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGG ACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCAT GTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGC CCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACT CGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGC AAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCT >In-frame_TESC_ENST00000392545_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_1327nt ATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGACCCGAGGCCGGACCCGAGGCCAGTCCCGC CGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGCGGGCACCATGGGCGCTGCCCACTCCGCG TCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCCTCCTTCAGGACCAACGTACAG AGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCTTGACAAGGCACCAGTGCTAAA GGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGTGGATGAAAAATTGCCTGGCCT ACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTTAGGAGAGATTATTTCATTCAA TATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGATTTTGG AGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAAAGAAA CAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACACTGAA TGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTCACTAG AACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATCCTGGG AGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGTAGATG GTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAACCGCAC CAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACCTTGAT >In-frame_TESC_ENST00000392545_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_1327nt ATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGACCCGAGGCCGGACCCGAGGCCAGTCCCGC CGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGCGGGCACCATGGGCGCTGCCCACTCCGCG TCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCCTCCTTCAGGACCAACGTACAG AGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCTTGACAAGGCACCAGTGCTAAA GGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGTGGATGAAAAATTGCCTGGCCT ACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTTAGGAGAGATTATTTCATTCAA TATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGATTTTGG AGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAAAGAAA CAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACACTGAA TGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTCACTAG AACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATCCTGGG AGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGTAGATG GTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAACCGCAC CAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACCTTGAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TESC_ENST00000335209_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_2464nt ACCGCGGCGCGCCGCCCTCCGCCGTTATATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGAC CCGAGGCCGGACCCGAGGCCAGTCCCGCCGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGC GGGCACCATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAA CCTATCCTCCTTCAGGACCAACGTACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAAT TGATGCTTGACAAGGCACCAGTGCTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGC AGGTGGTGGATGAAAAATTGCCTGGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATA TACCTTTAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATC TAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTT TAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCA AACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAG ATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGA TATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTAT ATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAA CGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCA ACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTT GGTGAGCACACGTCTGGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTC CAAAGACTAAGACTCGCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCC CTATCAGTTGATTTTTCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGAC ATTTGGGGATCTGGTGGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGT CTGTGTGAGTAACGGGACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTT TTCCTTCTGGTTCTAACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAG GGATGAGACAGACATTCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGT AATCAGTATGCAAAGCAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGC TAACTTAAAAAACTGCATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTA AATTCTCATAAGTAGCATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACT AAAATTATGTTACTGTATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACT GTGAAATGTACGTCATTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTG >In-frame_TESC_ENST00000335209_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_2463nt ACCGCGGCGCGCCGCCCTCCGCCGTTATATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGAC CCGAGGCCGGACCCGAGGCCAGTCCCGCCGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGC GGGCACCATGGGCGCTGCCCACTCCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAA CCTATCCTCCTTCAGGACCAACGTACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAAT TGATGCTTGACAAGGCACCAGTGCTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGC AGGTGGTGGATGAAAAATTGCCTGGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATA TACCTTTAGGAGAGATTATTTCATTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATC TAATACATGGGAGAAACATGGATTTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTT TAACAGTGAATTTGGATTTCCAAAGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCA AACCAGGACTGTTCAGTCTTACACTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAG ATGTCATGTGGATAGGGTTCCTCACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGA TATTGGCCCCAGCCTACTTTATCCTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTAT ATGAACTCGATGCTAAGCAGGGTAGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAA CGCCTGCAAAGATGTGTCTGAACCGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCA ACAAGCTGACCGTATACACAACCTTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTT GGTGAGCACACGTCTGGCCTACAGAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTC CAAAGACTAAGACTCGCGGCAGGTTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCC CTATCAGTTGATTTTTCTTATTTACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGAC ATTTGGGGATCTGGTGGGCAGTCGAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGT CTGTGTGAGTAACGGGACAGTAAACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTT TTCCTTCTGGTTCTAACTGCTGTTAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAG GGATGAGACAGACATTCACCTGTATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGT AATCAGTATGCAAAGCAATCTTTTATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGC TAACTTAAAAAACTGCATCCCACGTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTA AATTCTCATAAGTAGCATTCATGTAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACT AAAATTATGTTACTGTATTTTTCAGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACT GTGAAATGTACGTCATTTGTGCAAGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTG >In-frame_TESC_ENST00000541210_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_2441nt GTTATATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGACCCGAGGCCGGACCCGAGGCCAGT CCCGCCGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGCGGGCACCATGGGCGCTGCCCACT CCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCCTCCTTCAGGACCAACG TACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCTTGACAAGGCACCAGTG CTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGTGGATGAAAAATTGCCT GGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTTAGGAGAGATTATTTCA TTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGAT TTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAA AGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACA CTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTC ACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATC CTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGT AGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAAC CGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACC TTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACA GAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGG TTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTT ACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTC GAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAA ACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGT TAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGT ATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTT TATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCAC GTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATG TAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTC AGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCA AGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTGGAAAGAGTGCCAGTCAGCAGTCA >In-frame_TESC_ENST00000541210_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_2440nt GTTATATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGACCCGAGGCCGGACCCGAGGCCAGT CCCGCCGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGCGGGCACCATGGGCGCTGCCCACT CCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCCTCCTTCAGGACCAACG TACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCTTGACAAGGCACCAGTG CTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGTGGATGAAAAATTGCCT GGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTTAGGAGAGATTATTTCA TTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGAT TTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAA AGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACA CTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTC ACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATC CTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGT AGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAAC CGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACC TTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACA GAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGG TTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTT ACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTC GAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAA ACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGT TAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGT ATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTT TATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCAC GTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATG TAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTC AGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCA AGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTGGAAAGAGTGCCAGTCAGCAGTCA >In-frame_TESC_ENST00000392545_chr12_117537030_-_ASAH1_ENST00000262097_chr8_17933096_-_2441nt GTTATATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGACCCGAGGCCGGACCCGAGGCCAGT CCCGCCGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGCGGGCACCATGGGCGCTGCCCACT CCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCCTCCTTCAGGACCAACG TACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCTTGACAAGGCACCAGTG CTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGTGGATGAAAAATTGCCT GGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTTAGGAGAGATTATTTCA TTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGAT TTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAA AGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACA CTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTC ACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATC CTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGT AGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAAC CGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACC TTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACA GAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGG TTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTT ACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTC GAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAA ACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGT TAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGT ATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTT TATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCAC GTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATG TAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTC AGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCA AGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTGGAAAGAGTGCCAGTCAGCAGTCA >In-frame_TESC_ENST00000392545_chr12_117537030_-_ASAH1_ENST00000381733_chr8_17933096_-_2440nt GTTATATGAGGCCCCGCTCCGGCCCCACGCGGAACCCGCGGCTCCGAGCCTTCGCCGGCGTCCCGACCCGAGGCCGGACCCGAGGCCAGT CCCGCCGCTGCGCAGCCGAAGCCAGTGCGGGGCCTGAGAGGGACGCGCGCCCCGGGGCCCCCGCCGCGGGCACCATGGGCGCTGCCCACT CCGCGTCTGAGGAGGTGCGGGAGCTCGAGGGCAAGACCGGCTTGGACAGAGGACTGCAGAAAATCAACCTATCCTCCTTCAGGACCAACG TACAGAGGTGCAGTTCCATGGTACACCATAAATCTTGACTTACCACCCTACAAAAGATGGCATGAATTGATGCTTGACAAGGCACCAGTG CTAAAGGTTATAGTGAATTCTCTGAAGAATATGATAAATACATTCGTGCCAAGTGGAAAAATTATGCAGGTGGTGGATGAAAAATTGCCT GGCCTACTTGGCAACTTTCCTGGCCCTTTTGAAGAGGAAATGAAGGGTATTGCCGCTGTTACTGATATACCTTTAGGAGAGATTATTTCA TTCAATATTTTTTATGAATTATTTACCATTTGTACTTCAATAGTAGCAGAAGACAAAAAAGGTCATCTAATACATGGGAGAAACATGGAT TTTGGAGTATTTCTTGGGTGGAACATAAATAATGATACCTGGGTCATAACTGAGCAACTAAAACCTTTAACAGTGAATTTGGATTTCCAA AGAAACAACAAAACTGTCTTCAAGGCTTCAAGCTTTGCTGGCTATGTGGGCATGTTAACAGGATTCAAACCAGGACTGTTCAGTCTTACA CTGAATGAACGTTTCAGTATAAATGGTGGTTATCTGGGTATTCTAGAATGGATTCTGGGAAAGAAAGATGTCATGTGGATAGGGTTCCTC ACTAGAACAGTTCTGGAAAATAGCACAAGTTATGAAGAAGCCAAGAATTTATTGACCAAGACCAAGATATTGGCCCCAGCCTACTTTATC CTGGGAGGCAACCAGTCTGGGGAAGGTTGTGTGATTACACGAGACAGAAAGGAATCATTGGATGTATATGAACTCGATGCTAAGCAGGGT AGATGGTATGTGGTACAAACAAATTATGACCGTTGGAAACATCCCTTCTTCCTTGATGATCGCAGAACGCCTGCAAAGATGTGTCTGAAC CGCACCAGCCAAGAGAATATCTCATTTGAAACCATGTATGATGTCCTGTCAACAAAACCTGTCCTCAACAAGCTGACCGTATACACAACC TTGATAGATGTTACCAAAGGTCAATTCGAAACTTACCTGCGGGACTGCCCTGACCCTTGTATAGGTTGGTGAGCACACGTCTGGCCTACA GAATGCGGCCTCTGAGACATGAAGACACCATCTCCATGTGACCGAACACTGCAGCTGTCTGACCTTCCAAAGACTAAGACTCGCGGCAGG TTCTCTTTGAGTCAATAGCTTGTCTTCGTCCATCTGTTGACAAATGACAGATCTTTTTTTTTTCCCCCTATCAGTTGATTTTTCTTATTT ACAGATAACTTCTTTAGGGGAAGTAAAACAGTCATCTAGAATTCACTGAGTTTTGTTTCACTTTGACATTTGGGGATCTGGTGGGCAGTC GAACCATGGTGAACTCCACCTCCGTGGAATAAATGGAGATTCAGCGTGGGTGTTGAATCCAGCACGTCTGTGTGAGTAACGGGACAGTAA ACACTCCACATTCTTCAGTTTTTCACTTCTACCTACATATTTGTATGTTTTTCTGTATAACAGCCTTTTCCTTCTGGTTCTAACTGCTGT TAAAATTAATATATCATTATCTTTGCTGTTATTGACAGCGATATAATTTTATTACATATGATTAGAGGGATGAGACAGACATTCACCTGT ATATTTCTTTTAATGGGCACAAAATGGGCCCTTGCCTCTAAATAGCACTTTTTGGGGTTCAAGAAGTAATCAGTATGCAAAGCAATCTTT TATACAATAATTGAAGTGTTCCCTTTTTCATAATTACTCTACTTCCCAGTAACCCTAAGGAAGTTGCTAACTTAAAAAACTGCATCCCAC GTTCTGTTAATTTAGTAAATAAACAAGTCAAAGACTTGTGGAAAATAGGAAGTGAACCCATATTTTAAATTCTCATAAGTAGCATTCATG TAATAAACAGGTTTTTAGTTTGTTCTTCAGATTGATAGGGAGTTTTAAAGAAATTTTAGTAGTTACTAAAATTATGTTACTGTATTTTTC AGAAATCAAACTGCTTATGAAAAGTACTAATAGAACTTGTTAACCTTTCTAACCTTCACGATTAACTGTGAAATGTACGTCATTTGTGCA AGACCGTTTGTCCACTTCATTTTGTATAATCACAGTTGTGTTCCTGACACTCAATAAACAGTCACTGGAAAGAGTGCCAGTCAGCAGTCA |
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FusionGenePPI for TESC_ASAH1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TESC | HMG20A, RAI1, CCDC91, DYNLT3, SLC9A1, WBP11, LPAR1, IPPK | ASAH1 | SETDB1, TSC22D1, PSMA3, FBXO6, CAMK1D, SRPK1, GSG1, PNKD, AAGAB, AAMP, NEFH, CAMK2B, HSF2, HSPB2, HERC2, CYP1A2, GLT1D1, ZIC1, ZSCAN12, FTH1, NONO, TBC1D22B, SLCO6A1, AIRE, HTATIP2, RNF6, TRMT2A, ZNF684, ZNF556, HMP19, LYPD1, NCDN |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TESC_ASAH1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TESC_ASAH1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ASAH1 | C0268255 | Farber Lipogranulomatosis | 8 | CTD_human;ORPHANET;UNIPROT |
| Tgene | ASAH1 | C0023794 | Lipoidosis | 2 | CTD_human |
| Tgene | ASAH1 | C1834569 | Jankovic Rivera syndrome | 2 | ORPHANET;UNIPROT |
| Tgene | ASAH1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | ASAH1 | C0036341 | Schizophrenia | 1 | PSYGENET |
| Tgene | ASAH1 | C0221765 | Chronic schizophrenia | 1 | PSYGENET |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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