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Fusion gene ID: 37672 |
FusionGeneSummary for TEAD1_PARVA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TEAD1_PARVA | Fusion gene ID: 37672 | Hgene | Tgene | Gene symbol | TEAD1 | PARVA | Gene ID | 7003 | 55742 |
| Gene name | TEA domain transcription factor 1 | parvin alpha | |
| Synonyms | AA|NTEF-1|REF1|TCF-13|TCF13|TEAD-1|TEF-1 | CH-ILKBP|MXRA2 | |
| Cytomap | 11p15.3 | 11p15.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | transcriptional enhancer factor TEF-1TEA domain family member 1 (SV40 transcriptional enhancer factor)protein GT-IICtranscription factor 13transcriptional enhancer factor 1 | alpha-parvinactopaxincalponin-like integrin-linked kinase-binding proteinmatrix-remodeling-associated protein 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P28347 | Q9NVD7 | |
| Ensembl transtripts involved in fusion gene | ENST00000361905, ENST00000527636, ENST00000527575, ENST00000334310, ENST00000361985, ENST00000526600, | ENST00000334956, ENST00000539723, ENST00000550549, ENST00000538608, ENST00000526746, | |
| Fusion gene scores | * DoF score | 12 X 7 X 10=840 | 9 X 6 X 7=378 |
| # samples | 15 | 11 | |
| ** MAII score | log2(15/840*10)=-2.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/378*10)=-1.78088271069641 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TEAD1 [Title/Abstract] AND PARVA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TEAD1 | GO:0035329 | hippo signaling | 18579750|19324877 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-E7-A85H-01A | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| TCGA | RV | BRCA | TCGA-E2-A15E-01A | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| TCGA | RV | BRCA | TCGA-E2-A15E-06A | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000361905 | ENST00000334956 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000361905 | ENST00000539723 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000361905 | ENST00000550549 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000361905 | ENST00000538608 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000361905 | ENST00000526746 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| In-frame | ENST00000527636 | ENST00000334956 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000527636 | ENST00000539723 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000527636 | ENST00000550549 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000527636 | ENST00000538608 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000527636 | ENST00000526746 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| In-frame | ENST00000527575 | ENST00000334956 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000527575 | ENST00000539723 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000527575 | ENST00000550549 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000527575 | ENST00000538608 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000527575 | ENST00000526746 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| In-frame | ENST00000334310 | ENST00000334956 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000334310 | ENST00000539723 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000334310 | ENST00000550549 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000334310 | ENST00000538608 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000334310 | ENST00000526746 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| In-frame | ENST00000361985 | ENST00000334956 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000361985 | ENST00000539723 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| Frame-shift | ENST00000361985 | ENST00000550549 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000361985 | ENST00000538608 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5CDS-intron | ENST00000361985 | ENST00000526746 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| intron-3CDS | ENST00000526600 | ENST00000334956 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| intron-3CDS | ENST00000526600 | ENST00000539723 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| intron-3CDS | ENST00000526600 | ENST00000550549 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| intron-intron | ENST00000526600 | ENST00000538608 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| intron-intron | ENST00000526600 | ENST00000526746 | TEAD1 | chr11 | 12785981 | + | PARVA | chr11 | 12549396 | + |
| 5UTR-3CDS | ENST00000361905 | ENST00000334956 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000361905 | ENST00000539723 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000361905 | ENST00000550549 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000361905 | ENST00000538608 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000361905 | ENST00000526746 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000527636 | ENST00000334956 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000527636 | ENST00000539723 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000527636 | ENST00000550549 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000527636 | ENST00000538608 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000527636 | ENST00000526746 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000527575 | ENST00000334956 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000527575 | ENST00000539723 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000527575 | ENST00000550549 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000527575 | ENST00000538608 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000527575 | ENST00000526746 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000334310 | ENST00000334956 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000334310 | ENST00000539723 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-3CDS | ENST00000334310 | ENST00000550549 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000334310 | ENST00000538608 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| 5UTR-5UTR | ENST00000334310 | ENST00000526746 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-3CDS | ENST00000361985 | ENST00000334956 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-3CDS | ENST00000361985 | ENST00000539723 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-3CDS | ENST00000361985 | ENST00000550549 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-5UTR | ENST00000361985 | ENST00000538608 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-5UTR | ENST00000361985 | ENST00000526746 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-3CDS | ENST00000526600 | ENST00000334956 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-3CDS | ENST00000526600 | ENST00000539723 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-3CDS | ENST00000526600 | ENST00000550549 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-5UTR | ENST00000526600 | ENST00000538608 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
| intron-5UTR | ENST00000526600 | ENST00000526746 | TEAD1 | chr11 | 12697108 | + | PARVA | chr11 | 12495292 | + |
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FusionProtFeatures for TEAD1_PARVA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TEAD1 | PARVA |
| Transcription factor which plays a key role in the Hipposignaling pathway, a pathway involved in organ size control andtumor suppression by restricting proliferation and promotingapoptosis. The core of this pathway is composed of a kinasecascade wherein MST1/MST2, in complex with its regulatory proteinSAV1, phosphorylates and activates LATS1/2 in complex with itsregulatory protein MOB1, which in turn phosphorylates andinactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating geneexpression of YAP1 and WWTR1/TAZ, thereby regulating cellproliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds specifically and cooperatively to the SPHand GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activatestranscription in vivo in a cell-specific manner. The activationfunction appears to be mediated by a limiting cell-specifictranscriptional intermediary factor (TIF). Involved in cardiacdevelopment. Binds to the M-CAT motif.{ECO:0000269|PubMed:18579750, ECO:0000269|PubMed:19324877}. | Plays a role in sarcomere organization and in smoothmuscle cell contraction. Required for normal development of theembryonic cardiovascular system, and for normal septation of theheart outflow tract. Plays a role in sprouting angiogenesis and isrequired for normal adhesion of vascular smooth muscle cells toendothelial cells during blood vessel development (By similarity).Plays a role in the reorganization of the actin cytoskeleton,formation of lamellipodia and ciliogenesis. Plays a role in theestablishement of cell polarity, cell adhesion, cell spreading,and directed cell migration. {ECO:0000250,ECO:0000269|PubMed:11134073, ECO:0000269|PubMed:11331308,ECO:0000269|PubMed:15284246, ECO:0000269|PubMed:20393563}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TEAD1 | chr11:12785981 | chr11:12549396 | ENST00000361905 | + | 3 | 13 | 143_204 | 52 | 412 | Compositional bias | Note=Pro-rich |
| Hgene | >TEAD1 | chr11:12785981 | chr11:12549396 | ENST00000361905 | + | 3 | 13 | 306_328 | 52 | 412 | Compositional bias | Note=Ser/Thr/Tyr-rich |
| Hgene | >TEAD1 | chr11:12785981 | chr11:12549396 | ENST00000361905 | + | 3 | 13 | 28_104 | 52 | 412 | DNA binding | TEA |
| Hgene | >TEAD1 | chr11:12785981 | chr11:12549396 | ENST00000361905 | + | 3 | 13 | 167_426 | 52 | 412 | Region | Transcriptional activation |
| Tgene | PARVA | chr11:12785981 | chr11:12549396 | ENST00000550549 | + | 11 | 13 | 262_369 | 347 | 373 | Domain | Calponin-homology (CH) 2 |
| Tgene | PARVA | chr11:12785981 | chr11:12549396 | ENST00000550549 | + | 11 | 13 | 95_202 | 347 | 373 | Domain | Calponin-homology (CH) 1 |
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FusionGeneSequence for TEAD1_PARVA |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TEAD1_ENST00000361905_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_78aa >In-frame_TEAD1_ENST00000527636_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_93aa IEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYDIVNCDLKSTLRVLYNLFTKYRN >In-frame_TEAD1_ENST00000527575_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_93aa IEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYDIVNCDLKSTLRVLYNLFTKYRN >In-frame_TEAD1_ENST00000334310_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_78aa >In-frame_TEAD1_ENST00000361985_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_93aa IEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYDIVNCDLKSTLRVLYNLFTKYRN |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TEAD1_ENST00000361905_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_234nt ATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAG GCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAA >In-frame_TEAD1_ENST00000527636_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_279nt ATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGAT GCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTA TCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAAC >In-frame_TEAD1_ENST00000527575_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_279nt ATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGAT GCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTA TCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAAC >In-frame_TEAD1_ENST00000334310_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_234nt ATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAG GCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAA >In-frame_TEAD1_ENST00000361985_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_279nt ATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGAT GCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTA TCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TEAD1_ENST00000361905_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_3775nt TTCCGAACATTCTTAGCATCGCTCGCGCCGCGCCGCGCCGCCTGAGCCGAGCCGAGCCTCTGCTGCCGCCGCCGCGGCCCCGCCGCCCGC CGCGGGCGCCCACCAAGCACTTTGCAGACTCGCTTCCACCCTGCGGGCCATTCCGCGCGGCGGGGCCCGGGCCCGGGGCGGCCGCGTCCA GGCACAGGCCATGCAGTGACGCCCCCCCACCCCTCCACCTTTGCCCGGAGCGCGGGCAGCAGCCCAGCGCGCCAGCCGGCCCCGGGGCAG GAGCGGTGCTAGGCAGGGGTGGGGTGGCCGGGCCCAGGGACCGGGAGCCGGGGAGGGAGCCGGGCACCGAGCAGAGGGCGGGGGAAGCGG CGCCGAAGTTTGCCTCGGACTCGCCGGGCGCTGCGGTGGCTCCCTGGGCCGAGGACTGTTGCTGCCGCTGCCGCCGCCGCTTCATTGCAC ATTCAAGTGGAAAATTTTCAGGAGTCAGCAGAAACATTGTGTCCAAAAAAGACTGAGTCGCAGTTACCACCAAACCCAGGAGGAGACTCT CCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCGGCTTGGAAAATCCCACCGCCAAAATTGAGCCCA GCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGATGCAGAAGGGG TCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTATCAGACGAAG GCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAACGTGGAGTGAG GGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCTCCTCCGAACTGCCTTACCCTGCTTATTCCTGTC TCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAAATTAGGAAGGAAATCATCAATAACTCAGTGGGC TGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTGTTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTC CATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCCTAGTTACCATTCAAAGGATGCTAACTGTGTGTC AGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACTCCCATTGACGTAGGTGTTTCATTCCCCTTTTAC AGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTTCCTCTTTGAACATAACCTCTCCCTTCTCCCTAA AGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGTATGCATTCCTCAATAGTAGACAGTACAACATGT TTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGTGCACATCTGAGCACGTGCACATGTACACCTGAG CCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAGTGATTCACACTGAAATTGGCAAATTGGATTTAA CCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAATGAAAATTACTCTTAATTCCTTCAGATTTATAAT AACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATGGAGTGGCACATTTTGCAGCCTTTTTGCTTGATT GCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCGTTAAGCAAATGTACAATATGCTCAGGCACCGCA GAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGGGACCCTTGAACTTTAAAGAAAGGAACTTCTTTT TGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACCGGCTAATTCAAGCGAGGAAAAATGTAAGTCATT TAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTGTATCTCCTCTATGTGAACTTGACTTTGAAAGAC AGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGGGTGGGCAGTGACTAGGGGACGAGAAGCATGGGG AAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACACTTGTAGCCATCAACTGACTGAGACCTTGGGCTA AATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGGTAGACACCAGCCCAAGTACCCTCCTCCAGAAGT CTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGAGAATTCATTTTGATCTGTATCTACACCACCCAA AGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGTACTGTCTCTTACTGTACTGTCTATCTGCAGTAA TTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCAGCATAATGAGCATTTAACATACAAAGGCAATGT ACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAAATTTTATTTTTTATTAGGAAACACTAAATAGTG TAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGCTTCATTTTCTTGAGCAATACTGAAGCAGGATGA AGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTTTGGTCTCTTTTTCTTATATTCAAGTTACAAATG TACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAAATACATTGGAACACTAGGAAAGTTTTTAAATAA CAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAGAATCCCAGGTCCTGGGCCTGGTTTTCTAATGCT GTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGACCATGACTTTGAAAGGCAAAAGAGGAATCAAGAA TAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGAGAATCAACACTTCATAGGCTCACTGGGTTTTCT TTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGCAAAATTTAAAAAGCGCAAATAGGTATCTAGTGG AAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTGTTTTGATCCATTTCTTACACACACTGCCAGAGA TACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATATAAGTAGGATGTCATCTATACTGTCATACACTT >In-frame_TEAD1_ENST00000527636_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_3606nt GGCCGCGTCCAGGCACAGGCCATGCAGTGACGCCCCCCCACCCCTCCACCTTTGCCCGGAGCGCGGGCAGCAGCCCAGCGCGCCAGCCGG CCCCGGGGCAGGAGCGGTGCTAGGCAGGGGTGGGGTGGCCGGGCCCAGGGACCGGGAGCCGGGGAGGGAGCCGGGCACCGAGCAGAGGGC GGGGGAAGCGGCGCCGAAGTTTGCCTCGGACTCGCCGGGCGCTGCGGTGGCTCCCTGGGCCGAGGACTGTTGCTGCCGCTGCCGCCGCCG CTTCATTGCACATTCAAGTGGAAAATTTTCAGGAGTCAGCAGAAACATTGTGTCCAAAAAAGACTGAGTCGCAGTTACCACCAAACCCAG GAGGAGACTCTCCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCGGCTTGGAAAATCCCACCGCCAA AATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGA TGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTT ATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAA CGTGGAGTGAGGGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCTCCTCCGAACTGCCTTACCCTGC TTATTCCTGTCTCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAAATTAGGAAGGAAATCATCAATA ACTCAGTGGGCTGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTGTTCCCTTCCCGGTGCCAGGTCC AGATTTCCCTCCATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCCTAGTTACCATTCAAAGGATGCT AACTGTGTGTCAGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACTCCCATTGACGTAGGTGTTTCAT TCCCCTTTTACAGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTTCCTCTTTGAACATAACCTCTCC CTTCTCCCTAAAGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGTATGCATTCCTCAATAGTAGACA GTACAACATGTTTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGTGCACATCTGAGCACGTGCACAT GTACACCTGAGCCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAGTGATTCACACTGAAATTGGCAA ATTGGATTTAACCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAATGAAAATTACTCTTAATTCCTTC AGATTTATAATAACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATGGAGTGGCACATTTTGCAGCCTT TTTGCTTGATTGCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCGTTAAGCAAATGTACAATATGCT CAGGCACCGCAGAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGGGACCCTTGAACTTTAAAGAAAG GAACTTCTTTTTGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACCGGCTAATTCAAGCGAGGAAAAA TGTAAGTCATTTAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTGTATCTCCTCTATGTGAACTTGA CTTTGAAAGACAGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGGGTGGGCAGTGACTAGGGGACGA GAAGCATGGGGAAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACACTTGTAGCCATCAACTGACTGAG ACCTTGGGCTAAATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGGTAGACACCAGCCCAAGTACCCT CCTCCAGAAGTCTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGAGAATTCATTTTGATCTGTATCT ACACCACCCAAAGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGTACTGTCTCTTACTGTACTGTCT ATCTGCAGTAATTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCAGCATAATGAGCATTTAACATAC AAAGGCAATGTACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAAATTTTATTTTTTATTAGGAAAC ACTAAATAGTGTAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGCTTCATTTTCTTGAGCAATACTG AAGCAGGATGAAGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTTTGGTCTCTTTTTCTTATATTCA AGTTACAAATGTACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAAATACATTGGAACACTAGGAAAG TTTTTAAATAACAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAGAATCCCAGGTCCTGGGCCTGGT TTTCTAATGCTGTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGACCATGACTTTGAAAGGCAAAAGA GGAATCAAGAATAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGAGAATCAACACTTCATAGGCTCA CTGGGTTTTCTTTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGCAAAATTTAAAAAGCGCAAATAG GTATCTAGTGGAAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTGTTTTGATCCATTTCTTACACAC ACTGCCAGAGATACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATATAAGTAGGATGTCATCTATACT GTCATACACTTTGTTTTTTATCACTTAATGTTATATCTTGGATATTGTATTACCCTGGGTATTAAAAAGAACTCCTTTCACATTTTAAAA >In-frame_TEAD1_ENST00000527575_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_3268nt TCGCAGTTACCACCAAACCCAGGAGGAGACTCTCCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCG GCTTGGAAAATCCCACCGCCAAAATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTG CAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCAT GTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACA ACCTCTTCACCAAGTACCGTAACGTGGAGTGAGGGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCT CCTCCGAACTGCCTTACCCTGCTTATTCCTGTCTCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAA ATTAGGAAGGAAATCATCAATAACTCAGTGGGCTGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTG TTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTCCATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCC TAGTTACCATTCAAAGGATGCTAACTGTGTGTCAGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACT CCCATTGACGTAGGTGTTTCATTCCCCTTTTACAGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTT CCTCTTTGAACATAACCTCTCCCTTCTCCCTAAAGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGT ATGCATTCCTCAATAGTAGACAGTACAACATGTTTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGT GCACATCTGAGCACGTGCACATGTACACCTGAGCCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAG TGATTCACACTGAAATTGGCAAATTGGATTTAACCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAAT GAAAATTACTCTTAATTCCTTCAGATTTATAATAACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATG GAGTGGCACATTTTGCAGCCTTTTTGCTTGATTGCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCG TTAAGCAAATGTACAATATGCTCAGGCACCGCAGAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGG GACCCTTGAACTTTAAAGAAAGGAACTTCTTTTTGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACC GGCTAATTCAAGCGAGGAAAAATGTAAGTCATTTAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTG TATCTCCTCTATGTGAACTTGACTTTGAAAGACAGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGG GTGGGCAGTGACTAGGGGACGAGAAGCATGGGGAAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACAC TTGTAGCCATCAACTGACTGAGACCTTGGGCTAAATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGG TAGACACCAGCCCAAGTACCCTCCTCCAGAAGTCTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGA GAATTCATTTTGATCTGTATCTACACCACCCAAAGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGT ACTGTCTCTTACTGTACTGTCTATCTGCAGTAATTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCA GCATAATGAGCATTTAACATACAAAGGCAATGTACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAA ATTTTATTTTTTATTAGGAAACACTAAATAGTGTAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGC TTCATTTTCTTGAGCAATACTGAAGCAGGATGAAGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTT TGGTCTCTTTTTCTTATATTCAAGTTACAAATGTACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAA ATACATTGGAACACTAGGAAAGTTTTTAAATAACAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAG AATCCCAGGTCCTGGGCCTGGTTTTCTAATGCTGTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGAC CATGACTTTGAAAGGCAAAAGAGGAATCAAGAATAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGA GAATCAACACTTCATAGGCTCACTGGGTTTTCTTTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGC AAAATTTAAAAAGCGCAAATAGGTATCTAGTGGAAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTG TTTTGATCCATTTCTTACACACACTGCCAGAGATACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATA TAAGTAGGATGTCATCTATACTGTCATACACTTTGTTTTTTATCACTTAATGTTATATCTTGGATATTGTATTACCCTGGGTATTAAAAA >In-frame_TEAD1_ENST00000334310_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_3268nt TCGCAGTTACCACCAAACCCAGGAGGAGACTCTCCCTGGAAAACTTCCCTTCCCTTTCGGTTTATTTTCTTGAAAAGGCTCCAGGCTTCG GCTTGGAAAATCCCACCGCCAAAATTGAGCCCAGCAGCTGGAGCGGCAGTGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTG CAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACATCGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCAT GTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACATAGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACA ACCTCTTCACCAAGTACCGTAACGTGGAGTGAGGGGCTGCCCTGGGCCCACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCT CCTCCGAACTGCCTTACCCTGCTTATTCCTGTCTCTTGCACTGTGCTCTCCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAA ATTAGGAAGGAAATCATCAATAACTCAGTGGGCTGACCCATCCCTCCCAGGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTG TTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTCCATGATTTGGGAACCAGCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCC TAGTTACCATTCAAAGGATGCTAACTGTGTGTCAGGCCCCACACTAAGTGCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACT CCCATTGACGTAGGTGTTTCATTCCCCTTTTACAGATGAGGAAACTAAGGCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTT CCTCTTTGAACATAACCTCTCCCTTCTCCCTAAAGGTAACCACTATTCTGAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGT ATGCATTCCTCAATAGTAGACAGTACAACATGTTTATAACAAGCCAATTACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGT GCACATCTGAGCACGTGCACATGTACACCTGAGCCAAAAACACGAGAACCCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAG TGATTCACACTGAAATTGGCAAATTGGATTTAACCCAATTAATAGTGTGTGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAAT GAAAATTACTCTTAATTCCTTCAGATTTATAATAACTCTGTACTTTGGTTTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATG GAGTGGCACATTTTGCAGCCTTTTTGCTTGATTGCATGTAATGGAAATGCCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCG TTAAGCAAATGTACAATATGCTCAGGCACCGCAGAGAGCTGGGCACGGGCCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGG GACCCTTGAACTTTAAAGAAAGGAACTTCTTTTTGCCTTCTAATTGATCATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACC GGCTAATTCAAGCGAGGAAAAATGTAAGTCATTTAGACCAAAGCCAAGCAGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTG TATCTCCTCTATGTGAACTTGACTTTGAAAGACAGAGCTCTAGTGTGCCAGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGG GTGGGCAGTGACTAGGGGACGAGAAGCATGGGGAAAATATTTGCACTCTAAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACAC TTGTAGCCATCAACTGACTGAGACCTTGGGCTAAATAATCAATTGTGCTGATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGG TAGACACCAGCCCAAGTACCCTCCTCCAGAAGTCTGTGACTACCTTGTCACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGA GAATTCATTTTGATCTGTATCTACACCACCCAAAGTTAGGCCTCCTATAATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGT ACTGTCTCTTACTGTACTGTCTATCTGCAGTAATTGAGGACCCATAAAATTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCA GCATAATGAGCATTTAACATACAAAGGCAATGTACTGTTTTGTGTTGATCTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAA ATTTTATTTTTTATTAGGAAACACTAAATAGTGTAATATTTCTTTTGCTTTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGC TTCATTTTCTTGAGCAATACTGAAGCAGGATGAAGTAAGAGGAATGCATTCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTT TGGTCTCTTTTTCTTATATTCAAGTTACAAATGTACAAGTATCCTTACTAAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAA ATACATTGGAACACTAGGAAAGTTTTTAAATAACAGTTCTAATTTATCAGAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAG AATCCCAGGTCCTGGGCCTGGTTTTCTAATGCTGTCATCTCAGTTCGATATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGAC CATGACTTTGAAAGGCAAAAGAGGAATCAAGAATAAATAAAACAAACTTAATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGA GAATCAACACTTCATAGGCTCACTGGGTTTTCTTTTCTTTTCTGTTAATTTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGC AAAATTTAAAAAGCGCAAATAGGTATCTAGTGGAAAACCTAAGCCTCCCTCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTG TTTTGATCCATTTCTTACACACACTGCCAGAGATACTCTAGGCATGTAAAGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATA TAAGTAGGATGTCATCTATACTGTCATACACTTTGTTTTTTATCACTTAATGTTATATCTTGGATATTGTATTACCCTGGGTATTAAAAA >In-frame_TEAD1_ENST00000361985_chr11_12785981_+_PARVA_ENST00000334956_chr11_12549396_+_3309nt AGGGAGTGTGGTGGCATTGCTCTGCAGAGACATGAACAGCTCCCTGGGAGACACTGCTGGGGAAAGATGAGTCGAGTCTACGGTTTTTTC TCATCCTCCTGTTTATTTTCTTGAAAAGGCTCCAGGCTTCGGCTTGGAAAATCCCACCGCCAAAATTGAGCCCAGCAGCTGGAGCGGCAG TGAGAGCCCTGCCGAAAACATGGAAAGGATGAGTGACTCTGCAGATAAGCCAATTGACAATGATGCAGAAGGGGTCTGGAGCCCCGACAT CGAGCAAAGCTTTCAGGAGGCCCTGGCTATCTATCCACCATGTGGGAGGAGGAAAATCATCTTATCAGACGAAGGCAAAATGTATGACAT AGTCAACTGTGACCTGAAATCTACACTACGAGTGTTGTACAACCTCTTCACCAAGTACCGTAACGTGGAGTGAGGGGCTGCCCTGGGCCC ACCACTGCCCAAGAGTTCTTGCTGTTGGCGTACTGGACCCTCCTCCGAACTGCCTTACCCTGCTTATTCCTGTCTCTTGCACTGTGCTCT CCCACAAGTCCAGCTGCAACCCAGAGATAGTGGAAACTGAAATTAGGAAGGAAATCATCAATAACTCAGTGGGCTGACCCATCCCTCCCA GGCGCTGGGGACCAACCTAGCAATGAAGGTTGGGAAGGTTGTTCCCTTCCCGGTGCCAGGTCCAGATTTCCCTCCATGATTTGGGAACCA GCTTAGGCAAAAGAGTCCCCACAAGATGAAAATAAAGATCCTAGTTACCATTCAAAGGATGCTAACTGTGTGTCAGGCCCCACACTAAGT GCTCTGCTCTGATATACTCAAGGCCATTAATCTTCAGGACTCCCATTGACGTAGGTGTTTCATTCCCCTTTTACAGATGAGGAAACTAAG GCTTGGAGGTTAAATGACTTGCCAGAAGTTGGAATTTTTTTCCTCTTTGAACATAACCTCTCCCTTCTCCCTAAAGGTAACCACTATTCT GAGTCCAATCATCAAGGTTTTGCTTTTCTTTTTAGCTAAGTATGCATTCCTCAATAGTAGACAGTACAACATGTTTATAACAAGCCAATT ACATTATGTTCTTTGCATGTTCTAAAGTTGTGTATGTGTGTGCACATCTGAGCACGTGCACATGTACACCTGAGCCAAAAACACGAGAAC CCACTGATCTCACCACTGGGGCAAGCTAGGTCAGAGCTTAGTGATTCACACTGAAATTGGCAAATTGGATTTAACCCAATTAATAGTGTG TGTGTGGCAGGAGTCATGTCCCTCACATCCTTTGTACAAATGAAAATTACTCTTAATTCCTTCAGATTTATAATAACTCTGTACTTTGGT TTCAGGGTGACATTTGGGAAGGATTTTGTTTAGAATTAATGGAGTGGCACATTTTGCAGCCTTTTTGCTTGATTGCATGTAATGGAAATG CCCTATATTTTCCTGCAAAATAAGTACTAAATTCATTATCGTTAAGCAAATGTACAATATGCTCAGGCACCGCAGAGAGCTGGGCACGGG CCCATGTGAGCATCACTTTGGAAGTAGGGCTCTTCAACAGGGACCCTTGAACTTTAAAGAAAGGAACTTCTTTTTGCCTTCTAATTGATC ATTTAGACTATTCTGGCTAAGTCTGCCCACATGTAATTACCGGCTAATTCAAGCGAGGAAAAATGTAAGTCATTTAGACCAAAGCCAAGC AGTTTCTTTGCGTGGGTTACTCAAGGGCTTGTGGTTACTTGTATCTCCTCTATGTGAACTTGACTTTGAAAGACAGAGCTCTAGTGTGCC AGCCTGCTAAGTCCTGTAAGAATAGGGAAGGGCGGAGGGGGGTGGGCAGTGACTAGGGGACGAGAAGCATGGGGAAAATATTTGCACTCT AAACATACAGAGATAGAGGTGGGGCTTGTGGTACTTAACACTTGTAGCCATCAACTGACTGAGACCTTGGGCTAAATAATCAATTGTGCT GATATTACATCTCGTTATGGAATGTTCCTAAATATGCCAGGTAGACACCAGCCCAAGTACCCTCCTCCAGAAGTCTGTGACTACCTTGTC ACTACTTTAGGCCCATTCCACAAAGCCCATCTCTGGTTTGAGAATTCATTTTGATCTGTATCTACACCACCCAAAGTTAGGCCTCCTATA ATGTCCAAAACATTCCTTTCAGCCTTTTTATTTCTTACTGTACTGTCTCTTACTGTACTGTCTATCTGCAGTAATTGAGGACCCATAAAA TTTAGATAACTACATGTCTTTGCTCTTAGAATTGTCACTCAGCATAATGAGCATTTAACATACAAAGGCAATGTACTGTTTTGTGTTGAT CTATGTAAAAGAATACAATTCTTTTTTACATAATTAGTGAAATTTTATTTTTTATTAGGAAACACTAAATAGTGTAATATTTCTTTTGCT TTTAAAAAAATTCCTGGTAGCAAATCAAGATAAATAATTGCTTCATTTTCTTGAGCAATACTGAAGCAGGATGAAGTAAGAGGAATGCAT TCATTTAAACATGCTTTGCTTTATGAATTTTGTCTCTTTTTTGGTCTCTTTTTCTTATATTCAAGTTACAAATGTACAAGTATCCTTACT AAGAGTGCTCCTTTTGTATTTTACATATATACAGTATGAAAATACATTGGAACACTAGGAAAGTTTTTAAATAACAGTTCTAATTTATCA GAAAATTGTGTTTTGGGATTGAGTTCTTTGTCTCAGCCCAGAATCCCAGGTCCTGGGCCTGGTTTTCTAATGCTGTCATCTCAGTTCGAT ATTTTACTTTAGAACCTGGAATCTCCTACTTAATATATGACCATGACTTTGAAAGGCAAAAGAGGAATCAAGAATAAATAAAACAAACTT AATCTTCATCTTTAAAAAAAAGAAAAAAGAAACCAAAATGAGAATCAACACTTCATAGGCTCACTGGGTTTTCTTTTCTTTTCTGTTAAT TTAAACTCAGTTATTTTTAATGCTTAATACATACATGGTGCAAAATTTAAAAAGCGCAAATAGGTATCTAGTGGAAAACCTAAGCCTCCC TCTCTCCTCCGGCACCCATTACCTCTCCCTGGAGGCAACTGTTTTGATCCATTTCTTACACACACTGCCAGAGATACTCTAGGCATGTAA AGCACAAACATACATATAAAATCTGCGGGCTTCAAAAAATATAAGTAGGATGTCATCTATACTGTCATACACTTTGTTTTTTATCACTTA |
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FusionGenePPI for TEAD1_PARVA |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TEAD1 | VGLL4, NCOA1, VGLL1, MEF2C, MAX, SRF, SOX2, YAP1, HLA-DMB, INSR, GCAT, UBTD1, ZDHHC17, TEAD4, RAD51, WWTR1, FOXK2, SKI, TEAD2, TRIM25, PFKM | PARVA | ILK, DHX36, UBE3A, ELAVL1, APP, MLH1, SOX2, HSPH1, CARM1, CORO1B, CRMP1, OSBP, OTUD6B, PPAT, TBC1D17, UGP2, ZRANB2, RSU1, SEC24C, MOCOS, LIMS1, PARVB, IQGAP1, VPS11, GCA, DDX47, CHMP2A, CMTR2, DDX17, DPH5, HSPB2, UBQLN1, SNW1, CDC5L, CDH1, LPXN, CCNB1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | PARVA | chr11:12785981 | chr11:12549396 | ENST00000550549 | + | 11 | 13 | 21_25 | 347 | 373 | ARHGAP31 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TEAD1_PARVA |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TEAD1_PARVA |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | TEAD1 | C1862382 | SVEINSSON CHORIORETINAL ATROPHY | 1 | CTD_human;ORPHANET;UNIPROT |
| Tgene | PARVA | C0236969 | Substance-Related Disorders | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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