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Fusion gene ID: 37616 |
FusionGeneSummary for TCHP_IFT81 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TCHP_IFT81 | Fusion gene ID: 37616 | Hgene | Tgene | Gene symbol | TCHP | IFT81 | Gene ID | 84260 | 28981 |
| Gene name | trichoplein keratin filament binding | intraflagellar transport 81 | |
| Synonyms | TpMs | CDV-1|CDV-1R|CDV1|CDV1R|DV1|SRTD19 | |
| Cytomap | 12q24.11 | 12q24.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | trichoplein keratin filament-binding proteinmitochondrial protein with oncostatic activitymitostatintumor suppressor protein | intraflagellar transport protein 81 homologcarnitine deficiency-associated gene expressed in ventricle 1carnitine deficiency-associated protein expressed in ventricle 1 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9BT92 | Q8WYA0 | |
| Ensembl transtripts involved in fusion gene | ENST00000405876, ENST00000312777, ENST00000550780, | ENST00000552912, ENST00000242591, ENST00000361948, ENST00000549009, | |
| Fusion gene scores | * DoF score | 6 X 5 X 4=120 | 5 X 6 X 7=210 |
| # samples | 6 | 8 | |
| ** MAII score | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/210*10)=-1.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: TCHP [Title/Abstract] AND IFT81 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TCHP | GO:0006915 | apoptotic process | 18931701 |
| Hgene | TCHP | GO:0030308 | negative regulation of cell growth | 18931701 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | PRAD | TCGA-HC-7232-01A | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000405876 | ENST00000552912 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| In-frame | ENST00000405876 | ENST00000242591 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| 5CDS-intron | ENST00000405876 | ENST00000361948 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| 5CDS-intron | ENST00000405876 | ENST00000549009 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| In-frame | ENST00000312777 | ENST00000552912 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| In-frame | ENST00000312777 | ENST00000242591 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| 5CDS-intron | ENST00000312777 | ENST00000361948 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| 5CDS-intron | ENST00000312777 | ENST00000549009 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| intron-3CDS | ENST00000550780 | ENST00000552912 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| intron-3CDS | ENST00000550780 | ENST00000242591 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| intron-intron | ENST00000550780 | ENST00000361948 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
| intron-intron | ENST00000550780 | ENST00000549009 | TCHP | chr12 | 110346742 | + | IFT81 | chr12 | 110641669 | + |
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FusionProtFeatures for TCHP_IFT81 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TCHP | IFT81 |
| Tumor suppressor which has the ability to inhibit cellgrowth and be pro-apoptotic during cell stress. Inhibits cellgrowth in bladder and prostate cancer cells by a down-regulationof HSPB1 by inhibiting its phosphorylation. May act as a 'capping'or 'branching' protein for keratin filaments in the cellperiphery. May regulate K8/K18 filament and desmosome organizationmainly at the apical or peripheral regions of simple epithelialcells (PubMed:15731013, PubMed:18931701). Is a negative regulatorof ciliogenesis (PubMed:25270598). {ECO:0000269|PubMed:15731013,ECO:0000269|PubMed:18931701, ECO:0000269|PubMed:25270598}. | Component of the intraflagellar transport (IFT) complexB: together with IFT74, forms a tubulin-binding module thatspecifically mediates transport of tubulin within the cilium.Binds tubulin via its CH (calponin-homology)-like region(PubMed:23990561). Required for ciliogenesis (PubMed:27666822,PubMed:23990561). Required for proper regulation of SHH signaling(PubMed:27666822). {ECO:0000269|PubMed:23990561,ECO:0000269|PubMed:27666822}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TCHP | chr12:110346742 | chr12:110641669 | ENST00000312777 | + | 8 | 13 | 11_39 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | TCHP | chr12:110346742 | chr12:110641669 | ENST00000312777 | + | 8 | 13 | 66_136 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | TCHP | chr12:110346742 | chr12:110641669 | ENST00000405876 | + | 8 | 13 | 11_39 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | TCHP | chr12:110346742 | chr12:110641669 | ENST00000405876 | + | 8 | 13 | 66_136 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >IFT81 | chr12:110346742 | chr12:110641669 | ENST00000361948 | + | 0 | 12 | 132_258 | -183 | 432 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >IFT81 | chr12:110346742 | chr12:110641669 | ENST00000361948 | + | 0 | 12 | 306_389 | -183 | 432 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >IFT81 | chr12:110346742 | chr12:110641669 | ENST00000361948 | + | 0 | 12 | 416_456 | -183 | 432 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >IFT81 | chr12:110346742 | chr12:110641669 | ENST00000361948 | + | 0 | 12 | 490_622 | -183 | 432 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >IFT81 | chr12:110346742 | chr12:110641669 | ENST00000361948 | + | 0 | 12 | 2_121 | -183 | 432 | Region | Note=CH (calponin-homology)-like region |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000312777 | + | 8 | 13 | 163_353 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000312777 | + | 8 | 13 | 380_479 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000405876 | + | 8 | 13 | 163_353 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000405876 | + | 8 | 13 | 380_479 | 293 | 499 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000312777 | + | 8 | 13 | 70_482 | 293 | 499 | Compositional bias | Glu-rich |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000405876 | + | 8 | 13 | 70_482 | 293 | 499 | Compositional bias | Glu-rich |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000312777 | + | 8 | 13 | 259_425 | 293 | 499 | Region | Trichohyalin/plectin homology domain |
| Hgene | >TCHP | chr12:110346742 | chr12:110641669 | ENST00000405876 | + | 8 | 13 | 259_425 | 293 | 499 | Region | Trichohyalin/plectin homology domain |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000242591 | + | 13 | 19 | 132_258 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000242591 | + | 13 | 19 | 306_389 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000242591 | + | 13 | 19 | 416_456 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000242591 | + | 13 | 19 | 490_622 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000552912 | + | 13 | 19 | 132_258 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000552912 | + | 13 | 19 | 306_389 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000552912 | + | 13 | 19 | 416_456 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000552912 | + | 13 | 19 | 490_622 | 519 | 677 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000242591 | + | 13 | 19 | 2_121 | 519 | 677 | Region | Note=CH (calponin-homology)-like region |
| Tgene | IFT81 | chr12:110346742 | chr12:110641669 | ENST00000552912 | + | 13 | 19 | 2_121 | 519 | 677 | Region | Note=CH (calponin-homology)-like region |
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FusionGeneSequence for TCHP_IFT81 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TCHP_ENST00000405876_chr12_110346742_+_IFT81_ENST00000552912_chr12_110641669_+_451aa MALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQL MQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATA EQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAEL GRFLRHQYNAQLSRRTQQIQEELELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMK AYISSDQQEKRKAIREQYTKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQTSIGQVIQEGGEDRLIL >In-frame_TCHP_ENST00000405876_chr12_110346742_+_IFT81_ENST00000242591_chr12_110641669_+_451aa MALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQL MQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATA EQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAEL GRFLRHQYNAQLSRRTQQIQEELELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMK AYISSDQQEKRKAIREQYTKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQTSIGQVIQEGGEDRLIL >In-frame_TCHP_ENST00000312777_chr12_110346742_+_IFT81_ENST00000552912_chr12_110641669_+_451aa MALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQL MQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATA EQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAEL GRFLRHQYNAQLSRRTQQIQEELELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMK AYISSDQQEKRKAIREQYTKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQTSIGQVIQEGGEDRLIL >In-frame_TCHP_ENST00000312777_chr12_110346742_+_IFT81_ENST00000242591_chr12_110641669_+_451aa MALPTLPSYWCSQQRLNQQLARQREQEARLRQQWEQNSRYFRMSDICSSKQAEWSSKTSYQRSMHAYQREKMKEEKRRSLEARREKLRQL MQEEQDLLARELEELRLSMNLQERRIREQHGKLKSAKEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATA EQENKRYENEYERARREALERMKAEEERRQLEDKLQAEALLQQMEELKLKEVEATKLKKEQENLLKQRWELERLEEERKQMEAFRQKAEL GRFLRHQYNAQLSRRTQQIQEELELTQECDEKKSQYDSCAAGLESNRSKLEQEVRRLREECLQEESRYHYTNCMIKNLEVQLRRATDEMK AYISSDQQEKRKAIREQYTKNTAEQENLGKKLREKQKVIRESHGPNMKQAKMWRDLEQLMECKKQCFLKQQSQTSIGQVIQEGGEDRLIL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TCHP_ENST00000405876_chr12_110346742_+_IFT81_ENST00000552912_chr12_110641669_+_1353nt ATGGCGCTCCCGACGCTGCCGTCCTACTGGTGCAGCCAGCAGCGCCTGAATCAGCAGCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTT CGGCAGCAGTGGGAGCAGAACAGCCGTTACTTCAGGATGTCTGACATCTGCAGCTCCAAACAGGCAGAATGGAGCTCTAAAACCTCCTAC CAGCGGAGCATGCATGCCTATCAGCGGGAGAAGATGAAGGAGGAGAAGAGGAGGAGTCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTC ATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAACTGGAGGAGCTGAGGCTGAGCATGAACTTGCAGGAAAGAAGAATCCGGGAGCAGCAC GGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGGAAACTGATTGCTGAACAACTTTTGTACGAACACTGGAAAAAGAACAACCCGAAACTT CGAGAGATGGAGCTGGACCTTCACCAGAAGCATGTCGTAAACTCTTGGGAAATGCAGAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCA GAGCAAGAGAACAAACGGTATGAAAATGAATATGAAAGGGCCCGAAGGGAGGCGCTAGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAG CTGGAGGACAAGCTCCAGGCCGAGGCACTGCTGCAACAGATGGAGGAGCTGAAGCTGAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAG CAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTAGAGAGGCTGGAGGAAGAGCGAAAGCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTG GGGCGTTTCTTGAGACATCAGTATAACGCTCAACTCAGCAGACGCACACAGCAGATCCAAGAGGAGCTGGAACTGACCCAGGAGTGTGAT GAAAAGAAATCCCAGTATGATAGCTGTGCAGCAGGCCTCGAAAGCAATCGGTCCAAATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAA TGTCTTCAAGAAGAAAGTAGATACCATTATACAAATTGTATGATTAAGAACCTAGAAGTTCAACTTCGTCGTGCTACTGATGAGATGAAG GCATATATCTCTTCTGATCAACAAGAAAAAAGAAAGGCAATTAGGGAACAGTATACCAAAAATACTGCTGAACAAGAAAACCTTGGAAAG AAACTTCGGGAAAAACAAAAAGTTATACGAGAAAGTCATGGTCCAAATATGAAACAAGCAAAAATGTGGCGTGATTTGGAACAATTAATG GAATGTAAGAAACAGTGCTTTCTGAAACAACAAAGCCAAACTTCCATTGGTCAGGTAATTCAGGAGGGTGGGGAGGACCGGCTAATACTG >In-frame_TCHP_ENST00000405876_chr12_110346742_+_IFT81_ENST00000242591_chr12_110641669_+_1353nt ATGGCGCTCCCGACGCTGCCGTCCTACTGGTGCAGCCAGCAGCGCCTGAATCAGCAGCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTT CGGCAGCAGTGGGAGCAGAACAGCCGTTACTTCAGGATGTCTGACATCTGCAGCTCCAAACAGGCAGAATGGAGCTCTAAAACCTCCTAC CAGCGGAGCATGCATGCCTATCAGCGGGAGAAGATGAAGGAGGAGAAGAGGAGGAGTCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTC ATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAACTGGAGGAGCTGAGGCTGAGCATGAACTTGCAGGAAAGAAGAATCCGGGAGCAGCAC GGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGGAAACTGATTGCTGAACAACTTTTGTACGAACACTGGAAAAAGAACAACCCGAAACTT CGAGAGATGGAGCTGGACCTTCACCAGAAGCATGTCGTAAACTCTTGGGAAATGCAGAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCA GAGCAAGAGAACAAACGGTATGAAAATGAATATGAAAGGGCCCGAAGGGAGGCGCTAGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAG CTGGAGGACAAGCTCCAGGCCGAGGCACTGCTGCAACAGATGGAGGAGCTGAAGCTGAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAG CAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTAGAGAGGCTGGAGGAAGAGCGAAAGCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTG GGGCGTTTCTTGAGACATCAGTATAACGCTCAACTCAGCAGACGCACACAGCAGATCCAAGAGGAGCTGGAACTGACCCAGGAGTGTGAT GAAAAGAAATCCCAGTATGATAGCTGTGCAGCAGGCCTCGAAAGCAATCGGTCCAAATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAA TGTCTTCAAGAAGAAAGTAGATACCATTATACAAATTGTATGATTAAGAACCTAGAAGTTCAACTTCGTCGTGCTACTGATGAGATGAAG GCATATATCTCTTCTGATCAACAAGAAAAAAGAAAGGCAATTAGGGAACAGTATACCAAAAATACTGCTGAACAAGAAAACCTTGGAAAG AAACTTCGGGAAAAACAAAAAGTTATACGAGAAAGTCATGGTCCAAATATGAAACAAGCAAAAATGTGGCGTGATTTGGAACAATTAATG GAATGTAAGAAACAGTGCTTTCTGAAACAACAAAGCCAAACTTCCATTGGTCAGGTAATTCAGGAGGGTGGGGAGGACCGGCTAATACTG >In-frame_TCHP_ENST00000312777_chr12_110346742_+_IFT81_ENST00000552912_chr12_110641669_+_1353nt ATGGCGCTCCCGACGCTGCCGTCCTACTGGTGCAGCCAGCAGCGCCTGAATCAGCAGCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTT CGGCAGCAGTGGGAGCAGAACAGCCGTTACTTCAGGATGTCTGACATCTGCAGCTCCAAACAGGCAGAATGGAGCTCTAAAACCTCCTAC CAGCGGAGCATGCATGCCTATCAGCGGGAGAAGATGAAGGAGGAGAAGAGGAGGAGTCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTC ATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAACTGGAGGAGCTGAGGCTGAGCATGAACTTGCAGGAAAGAAGAATCCGGGAGCAGCAC GGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGGAAACTGATTGCTGAACAACTTTTGTACGAACACTGGAAAAAGAACAACCCGAAACTT CGAGAGATGGAGCTGGACCTTCACCAGAAGCATGTCGTAAACTCTTGGGAAATGCAGAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCA GAGCAAGAGAACAAACGGTATGAAAATGAATATGAAAGGGCCCGAAGGGAGGCGCTAGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAG CTGGAGGACAAGCTCCAGGCCGAGGCACTGCTGCAACAGATGGAGGAGCTGAAGCTGAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAG CAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTAGAGAGGCTGGAGGAAGAGCGAAAGCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTG GGGCGTTTCTTGAGACATCAGTATAACGCTCAACTCAGCAGACGCACACAGCAGATCCAAGAGGAGCTGGAACTGACCCAGGAGTGTGAT GAAAAGAAATCCCAGTATGATAGCTGTGCAGCAGGCCTCGAAAGCAATCGGTCCAAATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAA TGTCTTCAAGAAGAAAGTAGATACCATTATACAAATTGTATGATTAAGAACCTAGAAGTTCAACTTCGTCGTGCTACTGATGAGATGAAG GCATATATCTCTTCTGATCAACAAGAAAAAAGAAAGGCAATTAGGGAACAGTATACCAAAAATACTGCTGAACAAGAAAACCTTGGAAAG AAACTTCGGGAAAAACAAAAAGTTATACGAGAAAGTCATGGTCCAAATATGAAACAAGCAAAAATGTGGCGTGATTTGGAACAATTAATG GAATGTAAGAAACAGTGCTTTCTGAAACAACAAAGCCAAACTTCCATTGGTCAGGTAATTCAGGAGGGTGGGGAGGACCGGCTAATACTG >In-frame_TCHP_ENST00000312777_chr12_110346742_+_IFT81_ENST00000242591_chr12_110641669_+_1353nt ATGGCGCTCCCGACGCTGCCGTCCTACTGGTGCAGCCAGCAGCGCCTGAATCAGCAGCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTT CGGCAGCAGTGGGAGCAGAACAGCCGTTACTTCAGGATGTCTGACATCTGCAGCTCCAAACAGGCAGAATGGAGCTCTAAAACCTCCTAC CAGCGGAGCATGCATGCCTATCAGCGGGAGAAGATGAAGGAGGAGAAGAGGAGGAGTCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTC ATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAACTGGAGGAGCTGAGGCTGAGCATGAACTTGCAGGAAAGAAGAATCCGGGAGCAGCAC GGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGGAAACTGATTGCTGAACAACTTTTGTACGAACACTGGAAAAAGAACAACCCGAAACTT CGAGAGATGGAGCTGGACCTTCACCAGAAGCATGTCGTAAACTCTTGGGAAATGCAGAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCA GAGCAAGAGAACAAACGGTATGAAAATGAATATGAAAGGGCCCGAAGGGAGGCGCTAGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAG CTGGAGGACAAGCTCCAGGCCGAGGCACTGCTGCAACAGATGGAGGAGCTGAAGCTGAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAG CAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTAGAGAGGCTGGAGGAAGAGCGAAAGCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTG GGGCGTTTCTTGAGACATCAGTATAACGCTCAACTCAGCAGACGCACACAGCAGATCCAAGAGGAGCTGGAACTGACCCAGGAGTGTGAT GAAAAGAAATCCCAGTATGATAGCTGTGCAGCAGGCCTCGAAAGCAATCGGTCCAAATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAA TGTCTTCAAGAAGAAAGTAGATACCATTATACAAATTGTATGATTAAGAACCTAGAAGTTCAACTTCGTCGTGCTACTGATGAGATGAAG GCATATATCTCTTCTGATCAACAAGAAAAAAGAAAGGCAATTAGGGAACAGTATACCAAAAATACTGCTGAACAAGAAAACCTTGGAAAG AAACTTCGGGAAAAACAAAAAGTTATACGAGAAAGTCATGGTCCAAATATGAAACAAGCAAAAATGTGGCGTGATTTGGAACAATTAATG GAATGTAAGAAACAGTGCTTTCTGAAACAACAAAGCCAAACTTCCATTGGTCAGGTAATTCAGGAGGGTGGGGAGGACCGGCTAATACTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TCHP_ENST00000405876_chr12_110346742_+_IFT81_ENST00000552912_chr12_110641669_+_2049nt GGGCTCGTTGCCGGTGCAAACAGGGAGGAAACAGCCGGCGTTGCTGTAGCGCGTCTGGGAATTACACCGGGGGACTGGCCGGCCCGCTTC GTGCCTGCGGGAAGTCGGGCCGGGGGACTCTTCGGAAACTCCGAGCCTCAGAGAAATATGGCGCTCCCGACGCTGCCGTCCTACTGGTGC AGCCAGCAGCGCCTGAATCAGCAGCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTTCGGCAGCAGTGGGAGCAGAACAGCCGTTACTTC AGGATGTCTGACATCTGCAGCTCCAAACAGGCAGAATGGAGCTCTAAAACCTCCTACCAGCGGAGCATGCATGCCTATCAGCGGGAGAAG ATGAAGGAGGAGAAGAGGAGGAGTCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTCATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAA CTGGAGGAGCTGAGGCTGAGCATGAACTTGCAGGAAAGAAGAATCCGGGAGCAGCACGGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGG AAACTGATTGCTGAACAACTTTTGTACGAACACTGGAAAAAGAACAACCCGAAACTTCGAGAGATGGAGCTGGACCTTCACCAGAAGCAT GTCGTAAACTCTTGGGAAATGCAGAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCAGAGCAAGAGAACAAACGGTATGAAAATGAATAT GAAAGGGCCCGAAGGGAGGCGCTAGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAGCTGGAGGACAAGCTCCAGGCCGAGGCACTGCTG CAACAGATGGAGGAGCTGAAGCTGAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAGCAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTA GAGAGGCTGGAGGAAGAGCGAAAGCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTGGGGCGTTTCTTGAGACATCAGTATAACGCTCAA CTCAGCAGACGCACACAGCAGATCCAAGAGGAGCTGGAACTGACCCAGGAGTGTGATGAAAAGAAATCCCAGTATGATAGCTGTGCAGCA GGCCTCGAAAGCAATCGGTCCAAATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAATGTCTTCAAGAAGAAAGTAGATACCATTATACA AATTGTATGATTAAGAACCTAGAAGTTCAACTTCGTCGTGCTACTGATGAGATGAAGGCATATATCTCTTCTGATCAACAAGAAAAAAGA AAGGCAATTAGGGAACAGTATACCAAAAATACTGCTGAACAAGAAAACCTTGGAAAGAAACTTCGGGAAAAACAAAAAGTTATACGAGAA AGTCATGGTCCAAATATGAAACAAGCAAAAATGTGGCGTGATTTGGAACAATTAATGGAATGTAAGAAACAGTGCTTTCTGAAACAACAA AGCCAAACTTCCATTGGTCAGGTAATTCAGGAGGGTGGGGAGGACCGGCTAATACTGTGAATTCTTGTGTCATCGTTTGGGGTTTTACTT GATACCACTAGCTATAAGCCTAATCTCATAATGTATTTCTTTTTTGAAACTGATTTGTATAGCATTTTGTTTTCAGAAGAGCCATTCTTT ATTAAGTTTTCATAGAAAATAATGTTAAGGTAGATTTAGTTTGAATGTTTTTTCATATGAAAAAGAGGCTTTTATTCTTTTCCATAGTTT AGACATCACTGGCGTCTTCTGAGTTTTATGAGACAGGAAACTAAGTTTACTATCTGTAAATGTAAACATATGTCCATTAAGAAACATGTA GTTTTTTTTTAGAATGTAATAACCCAGTGGCTTACTGTTTTTCTTAATCTCTTTTAAAAAAACTTTAGAAGAATCTTTTAGGAACTAATA TCTCTTGTTCTGAAGAAACATTTATCTGACGTTCAGCAGTTCCTACAGTTTTACTTCAGTTTATTTTTCTTCTGTAAAATGCAAGAAAAT >In-frame_TCHP_ENST00000405876_chr12_110346742_+_IFT81_ENST00000242591_chr12_110641669_+_2071nt GGGCTCGTTGCCGGTGCAAACAGGGAGGAAACAGCCGGCGTTGCTGTAGCGCGTCTGGGAATTACACCGGGGGACTGGCCGGCCCGCTTC GTGCCTGCGGGAAGTCGGGCCGGGGGACTCTTCGGAAACTCCGAGCCTCAGAGAAATATGGCGCTCCCGACGCTGCCGTCCTACTGGTGC AGCCAGCAGCGCCTGAATCAGCAGCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTTCGGCAGCAGTGGGAGCAGAACAGCCGTTACTTC AGGATGTCTGACATCTGCAGCTCCAAACAGGCAGAATGGAGCTCTAAAACCTCCTACCAGCGGAGCATGCATGCCTATCAGCGGGAGAAG ATGAAGGAGGAGAAGAGGAGGAGTCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTCATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAA CTGGAGGAGCTGAGGCTGAGCATGAACTTGCAGGAAAGAAGAATCCGGGAGCAGCACGGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGG AAACTGATTGCTGAACAACTTTTGTACGAACACTGGAAAAAGAACAACCCGAAACTTCGAGAGATGGAGCTGGACCTTCACCAGAAGCAT GTCGTAAACTCTTGGGAAATGCAGAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCAGAGCAAGAGAACAAACGGTATGAAAATGAATAT GAAAGGGCCCGAAGGGAGGCGCTAGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAGCTGGAGGACAAGCTCCAGGCCGAGGCACTGCTG CAACAGATGGAGGAGCTGAAGCTGAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAGCAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTA GAGAGGCTGGAGGAAGAGCGAAAGCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTGGGGCGTTTCTTGAGACATCAGTATAACGCTCAA CTCAGCAGACGCACACAGCAGATCCAAGAGGAGCTGGAACTGACCCAGGAGTGTGATGAAAAGAAATCCCAGTATGATAGCTGTGCAGCA GGCCTCGAAAGCAATCGGTCCAAATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAATGTCTTCAAGAAGAAAGTAGATACCATTATACA AATTGTATGATTAAGAACCTAGAAGTTCAACTTCGTCGTGCTACTGATGAGATGAAGGCATATATCTCTTCTGATCAACAAGAAAAAAGA AAGGCAATTAGGGAACAGTATACCAAAAATACTGCTGAACAAGAAAACCTTGGAAAGAAACTTCGGGAAAAACAAAAAGTTATACGAGAA AGTCATGGTCCAAATATGAAACAAGCAAAAATGTGGCGTGATTTGGAACAATTAATGGAATGTAAGAAACAGTGCTTTCTGAAACAACAA AGCCAAACTTCCATTGGTCAGGTAATTCAGGAGGGTGGGGAGGACCGGCTAATACTGTGAATTCTTGTGTCATCGTTTGGGGTTTTACTT GATACCACTAGCTATAAGCCTAATCTCATAATGTATTTCTTTTTTGAAACTGATTTGTATAGCATTTTGTTTTCAGAAGAGCCATTCTTT ATTAAGTTTTCATAGAAAATAATGTTAAGGTAGATTTAGTTTGAATGTTTTTTCATATGAAAAAGAGGCTTTTATTCTTTTCCATAGTTT AGACATCACTGGCGTCTTCTGAGTTTTATGAGACAGGAAACTAAGTTTACTATCTGTAAATGTAAACATATGTCCATTAAGAAACATGTA GTTTTTTTTTAGAATGTAATAACCCAGTGGCTTACTGTTTTTCTTAATCTCTTTTAAAAAAACTTTAGAAGAATCTTTTAGGAACTAATA TCTCTTGTTCTGAAGAAACATTTATCTGACGTTCAGCAGTTCCTACAGTTTTACTTCAGTTTATTTTTCTTCTGTAAAATGCAAGAAAAT TTAATATTTTGACTAACATGTCTTTTCTGTTTGTATCATTTAAAGGCAAATAAACTTGGTACGTATTTCATATCTATTTAAAAAATGTAT >In-frame_TCHP_ENST00000312777_chr12_110346742_+_IFT81_ENST00000552912_chr12_110641669_+_2116nt GGGCGCGAGCTCAGGGCGCCTCCGGGGTCCTCACTGCGCTCCCCACGCGCTGTGACCCCATTTGTTGCACGTGCATGTTCAGGTCGAGAG AGGGATGCGACGTGTTCGGGGAGCAGCCCACCTTGTGGGTGGCCAATCCGGGACGGGAATCTTAAACTTTTAACTCTTGGTGCAAAGACT GATCCACTGGCGGCTTTACGGGAGCGGGAAAAAAATGGCGCTCCCGACGCTGCCGTCCTACTGGTGCAGCCAGCAGCGCCTGAATCAGCA GCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTTCGGCAGCAGTGGGAGCAGAACAGCCGTTACTTCAGGATGTCTGACATCTGCAGCTC CAAACAGGCAGAATGGAGCTCTAAAACCTCCTACCAGCGGAGCATGCATGCCTATCAGCGGGAGAAGATGAAGGAGGAGAAGAGGAGGAG TCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTCATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAACTGGAGGAGCTGAGGCTGAGCAT GAACTTGCAGGAAAGAAGAATCCGGGAGCAGCACGGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGGAAACTGATTGCTGAACAACTTTT GTACGAACACTGGAAAAAGAACAACCCGAAACTTCGAGAGATGGAGCTGGACCTTCACCAGAAGCATGTCGTAAACTCTTGGGAAATGCA GAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCAGAGCAAGAGAACAAACGGTATGAAAATGAATATGAAAGGGCCCGAAGGGAGGCGCT AGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAGCTGGAGGACAAGCTCCAGGCCGAGGCACTGCTGCAACAGATGGAGGAGCTGAAGCT GAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAGCAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTAGAGAGGCTGGAGGAAGAGCGAAA GCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTGGGGCGTTTCTTGAGACATCAGTATAACGCTCAACTCAGCAGACGCACACAGCAGAT CCAAGAGGAGCTGGAACTGACCCAGGAGTGTGATGAAAAGAAATCCCAGTATGATAGCTGTGCAGCAGGCCTCGAAAGCAATCGGTCCAA ATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAATGTCTTCAAGAAGAAAGTAGATACCATTATACAAATTGTATGATTAAGAACCTAGA AGTTCAACTTCGTCGTGCTACTGATGAGATGAAGGCATATATCTCTTCTGATCAACAAGAAAAAAGAAAGGCAATTAGGGAACAGTATAC CAAAAATACTGCTGAACAAGAAAACCTTGGAAAGAAACTTCGGGAAAAACAAAAAGTTATACGAGAAAGTCATGGTCCAAATATGAAACA AGCAAAAATGTGGCGTGATTTGGAACAATTAATGGAATGTAAGAAACAGTGCTTTCTGAAACAACAAAGCCAAACTTCCATTGGTCAGGT AATTCAGGAGGGTGGGGAGGACCGGCTAATACTGTGAATTCTTGTGTCATCGTTTGGGGTTTTACTTGATACCACTAGCTATAAGCCTAA TCTCATAATGTATTTCTTTTTTGAAACTGATTTGTATAGCATTTTGTTTTCAGAAGAGCCATTCTTTATTAAGTTTTCATAGAAAATAAT GTTAAGGTAGATTTAGTTTGAATGTTTTTTCATATGAAAAAGAGGCTTTTATTCTTTTCCATAGTTTAGACATCACTGGCGTCTTCTGAG TTTTATGAGACAGGAAACTAAGTTTACTATCTGTAAATGTAAACATATGTCCATTAAGAAACATGTAGTTTTTTTTTAGAATGTAATAAC CCAGTGGCTTACTGTTTTTCTTAATCTCTTTTAAAAAAACTTTAGAAGAATCTTTTAGGAACTAATATCTCTTGTTCTGAAGAAACATTT ATCTGACGTTCAGCAGTTCCTACAGTTTTACTTCAGTTTATTTTTCTTCTGTAAAATGCAAGAAAATTTAATATTTTGACTAACATGTCT >In-frame_TCHP_ENST00000312777_chr12_110346742_+_IFT81_ENST00000242591_chr12_110641669_+_2138nt GGGCGCGAGCTCAGGGCGCCTCCGGGGTCCTCACTGCGCTCCCCACGCGCTGTGACCCCATTTGTTGCACGTGCATGTTCAGGTCGAGAG AGGGATGCGACGTGTTCGGGGAGCAGCCCACCTTGTGGGTGGCCAATCCGGGACGGGAATCTTAAACTTTTAACTCTTGGTGCAAAGACT GATCCACTGGCGGCTTTACGGGAGCGGGAAAAAAATGGCGCTCCCGACGCTGCCGTCCTACTGGTGCAGCCAGCAGCGCCTGAATCAGCA GCTAGCACGACAGCGAGAGCAGGAGGCCCGGCTTCGGCAGCAGTGGGAGCAGAACAGCCGTTACTTCAGGATGTCTGACATCTGCAGCTC CAAACAGGCAGAATGGAGCTCTAAAACCTCCTACCAGCGGAGCATGCATGCCTATCAGCGGGAGAAGATGAAGGAGGAGAAGAGGAGGAG TCTGGAGGCCCGACGGGAAAAGCTCAGGCAGCTCATGCAGGAGGAGCAGGACCTGCTGGCCAGAGAACTGGAGGAGCTGAGGCTGAGCAT GAACTTGCAGGAAAGAAGAATCCGGGAGCAGCACGGGAAGCTGAAATCAGCCAAAGAAGAGCAGAGGAAACTGATTGCTGAACAACTTTT GTACGAACACTGGAAAAAGAACAACCCGAAACTTCGAGAGATGGAGCTGGACCTTCACCAGAAGCATGTCGTAAACTCTTGGGAAATGCA GAAAGAAGAAAAAAAACAGCAAGAAGCCACCGCAGAGCAAGAGAACAAACGGTATGAAAATGAATATGAAAGGGCCCGAAGGGAGGCGCT AGAAAGGATGAAAGCTGAAGAGGAGAGGAGGCAGCTGGAGGACAAGCTCCAGGCCGAGGCACTGCTGCAACAGATGGAGGAGCTGAAGCT GAAGGAGGTGGAGGCGACCAAACTAAAGAAGGAGCAGGAGAATCTGTTGAAGCAGCGGTGGGAGCTAGAGAGGCTGGAGGAAGAGCGAAA GCAGATGGAAGCCTTCCGGCAGAAGGCAGAGCTGGGGCGTTTCTTGAGACATCAGTATAACGCTCAACTCAGCAGACGCACACAGCAGAT CCAAGAGGAGCTGGAACTGACCCAGGAGTGTGATGAAAAGAAATCCCAGTATGATAGCTGTGCAGCAGGCCTCGAAAGCAATCGGTCCAA ATTAGAACAGGAAGTTAGAAGACTCCGTGAAGAATGTCTTCAAGAAGAAAGTAGATACCATTATACAAATTGTATGATTAAGAACCTAGA AGTTCAACTTCGTCGTGCTACTGATGAGATGAAGGCATATATCTCTTCTGATCAACAAGAAAAAAGAAAGGCAATTAGGGAACAGTATAC CAAAAATACTGCTGAACAAGAAAACCTTGGAAAGAAACTTCGGGAAAAACAAAAAGTTATACGAGAAAGTCATGGTCCAAATATGAAACA AGCAAAAATGTGGCGTGATTTGGAACAATTAATGGAATGTAAGAAACAGTGCTTTCTGAAACAACAAAGCCAAACTTCCATTGGTCAGGT AATTCAGGAGGGTGGGGAGGACCGGCTAATACTGTGAATTCTTGTGTCATCGTTTGGGGTTTTACTTGATACCACTAGCTATAAGCCTAA TCTCATAATGTATTTCTTTTTTGAAACTGATTTGTATAGCATTTTGTTTTCAGAAGAGCCATTCTTTATTAAGTTTTCATAGAAAATAAT GTTAAGGTAGATTTAGTTTGAATGTTTTTTCATATGAAAAAGAGGCTTTTATTCTTTTCCATAGTTTAGACATCACTGGCGTCTTCTGAG TTTTATGAGACAGGAAACTAAGTTTACTATCTGTAAATGTAAACATATGTCCATTAAGAAACATGTAGTTTTTTTTTAGAATGTAATAAC CCAGTGGCTTACTGTTTTTCTTAATCTCTTTTAAAAAAACTTTAGAAGAATCTTTTAGGAACTAATATCTCTTGTTCTGAAGAAACATTT ATCTGACGTTCAGCAGTTCCTACAGTTTTACTTCAGTTTATTTTTCTTCTGTAAAATGCAAGAAAATTTAATATTTTGACTAACATGTCT 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FusionGenePPI for TCHP_IFT81 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TCHP | VIM, KRT15, NME7, CCDC85B, TEX11, CUL4A, LATS2, CDR2, NAB2, TRIM27, MKRN3, NDOR1, LZTS2, KRT40, DYDC1, MIPOL1, CCDC172, GLUL, LTBR, BTRC, MED4, SSX2IP, OFD1, PCM1, CEP170, KIAA0753, CEP104, CEP162, CEP290, CEP152, CNTROB, SPICE1, CEP128, CEP135, CEP44, CEP63, CEP89, CNTRL, NINL, NIN, ODF2, RPGRIP1L, LCA5, POC1A, STIL, CENPJ, IFFO1, KCTD17, SPAG16, TUBG1, AMPD2 | IFT81 | APP, IFT88, IFT57, CCDC151, ARL13B, IFT46, PRAME, IFT74, SPATA5L1, NDC80, CEP44, PCM1, LTBR, NTRK1, MED4, LCA5, OFD1, CEP128, CEP63, CNTRL, FBF1, NINL, ODF2, GLI1, UBXN10, TTC30A, TTC30B, JPH4, FGF8, RHPN1, SERPINB2, CORO6, HSPB11, IFT52, IFT27, IFT22, IFT172, TTC26, CCDC28B, IFT20, IFT80 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | TCHP | chr12:110346742 | chr12:110641669 | ENST00000312777 | + | 8 | 13 | 73_498 | 293 | 499 | keratin proteins |
| Hgene | TCHP | chr12:110346742 | chr12:110641669 | ENST00000405876 | + | 8 | 13 | 73_498 | 293 | 499 | keratin proteins |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TCHP_IFT81 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TCHP_IFT81 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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