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Fusion gene ID: 37350 |
FusionGeneSummary for TBC1D19_ANAPC4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TBC1D19_ANAPC4 | Fusion gene ID: 37350 | Hgene | Tgene | Gene symbol | TBC1D19 | ANAPC4 | Gene ID | 55296 | 29945 |
| Gene name | TBC1 domain family member 19 | anaphase promoting complex subunit 4 | |
| Synonyms | - | APC4 | |
| Cytomap | 4p15.2 | 4p15.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | TBC1 domain family member 19 | anaphase-promoting complex subunit 4cyclosome subunit 4 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8N5T2 | Q9UJX5 | |
| Ensembl transtripts involved in fusion gene | ENST00000264866, ENST00000511789, ENST00000515568, | ENST00000315368, ENST00000510092, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 2 X 2 X 2=8 |
| # samples | 2 | 2 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: TBC1D19 [Title/Abstract] AND ANAPC4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ANAPC4 | GO:0070979 | protein K11-linked ubiquitination | 18485873 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | HNSC | TCGA-HD-7753-01A | TBC1D19 | chr4 | 26641809 | + | ANAPC4 | chr4 | 25381996 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000264866 | ENST00000315368 | TBC1D19 | chr4 | 26641809 | + | ANAPC4 | chr4 | 25381996 | + |
| In-frame | ENST00000264866 | ENST00000510092 | TBC1D19 | chr4 | 26641809 | + | ANAPC4 | chr4 | 25381996 | + |
| In-frame | ENST00000511789 | ENST00000315368 | TBC1D19 | chr4 | 26641809 | + | ANAPC4 | chr4 | 25381996 | + |
| In-frame | ENST00000511789 | ENST00000510092 | TBC1D19 | chr4 | 26641809 | + | ANAPC4 | chr4 | 25381996 | + |
| 3UTR-3CDS | ENST00000515568 | ENST00000315368 | TBC1D19 | chr4 | 26641809 | + | ANAPC4 | chr4 | 25381996 | + |
| 3UTR-3CDS | ENST00000515568 | ENST00000510092 | TBC1D19 | chr4 | 26641809 | + | ANAPC4 | chr4 | 25381996 | + |
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FusionProtFeatures for TBC1D19_ANAPC4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TBC1D19 | ANAPC4 |
| May act as a GTPase-activating protein for Rab familyprotein(s). | Component of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated E3 ubiquitin ligase that controlsprogression through mitosis and the G1 phase of the cell cycle.The APC/C complex acts by mediating ubiquitination and subsequentdegradation of target proteins: it mainly mediates the formationof 'Lys-11'-linked polyubiquitin chains and, to a lower extent,the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitinchains. {ECO:0000269|PubMed:18485873}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TBC1D19 | chr4:26641809 | chr4:25381996 | ENST00000264866 | + | 7 | 21 | 251_472 | 160 | 527 | Domain | Rab-GAP TBC |
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FusionGeneSequence for TBC1D19_ANAPC4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TBC1D19_ENST00000264866_chr4_26641809_+_ANAPC4_ENST00000315368_chr4_25381996_+_926aa MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWASLQRPEIKLESLKEDIKEFFKISGWEKKLQNAVYSELSVFPLPSHPAAPPEHLKEP LVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLLHRLASFHRVWSFPPNEN TGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFSVEAPVSCMHWMEVTVESSVLTSFYNAEDESNLLLPKLPTLPKNYSNTS KIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLSVVTEVSTNGASEVSYFQLETNLLYS FLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLLLWGKASAELQTLLMNQLTVKGLKKL GQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDAAGIEEAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYV AMLRMTEDHVLPELNKMTQKDITFVAEFLTEHFNEAPDLYNRKGKYFNVERVGQYLKDEDDDLVSPPNTEGNQWYDFLQNSSHLKESPLL FPYYPRKSLHFVKRRMENIIDQCLQKPADVIGKSMNQAICIPLYRDTRSEDSTRRLFKFPFLWNNKTSNLHYLLFTILEDSLYKMCILRR HTDISQSVSNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLKDTVGREGRDRLLVQLPLSLVYNSEDSAEYQFTGTYSTRL DEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDESSDEEEEASNKPVKIKEEVLSESEAEN >In-frame_TBC1D19_ENST00000264866_chr4_26641809_+_ANAPC4_ENST00000510092_chr4_25381996_+_927aa MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWASLQRPEIKLESLKEDIKEFFKISGWEKKLQNAVYSELSVFPLPSHPAAPPEHLKEP LVYMRKAQGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAPKDFLEVLLHRLASFHRVWSFPPNEN TGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFSVEAPVSCMHWMEVTVESSVLTSFYNAEDESNLLLPKLPTLPKNYSNTS KIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLSVVTEVSTNGASEVSYFQLETNLLYS FLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLLLWGKASAELQTLLMNQLTVKGLKKL GQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDAAGIEEAITAVGSFILKANELLQVIDSSMKNFKAFFRWLYV AMLRMTEDHVLPELNKVMTQKDITFVAEFLTEHFNEAPDLYNRKGKYFNVERVGQYLKDEDDDLVSPPNTEGNQWYDFLQNSSHLKESPL LFPYYPRKSLHFVKRRMENIIDQCLQKPADVIGKSMNQAICIPLYRDTRSEDSTRRLFKFPFLWNNKTSNLHYLLFTILEDSLYKMCILR RHTDISQSVSNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLKDTVGREGRDRLLVQLPLSLVYNSEDSAEYQFTGTYSTR LDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDESSDEEEEASNKPVKIKEEVLSESEAE >In-frame_TBC1D19_ENST00000511789_chr4_26641809_+_ANAPC4_ENST00000315368_chr4_25381996_+_861aa MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAP KDFLEVLLHRLASFHRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFSVEAPVSCMHWMEVTVESSVLTSF YNAEDESNLLLPKLPTLPKNYSNTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLS VVTEVSTNGASEVSYFQLETNLLYSFLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLL LWGKASAELQTLLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDAAGIEEAITAVGSFIL KANELLQVIDSSMKNFKAFFRWLYVAMLRMTEDHVLPELNKMTQKDITFVAEFLTEHFNEAPDLYNRKGKYFNVERVGQYLKDEDDDLVS PPNTEGNQWYDFLQNSSHLKESPLLFPYYPRKSLHFVKRRMENIIDQCLQKPADVIGKSMNQAICIPLYRDTRSEDSTRRLFKFPFLWNN KTSNLHYLLFTILEDSLYKMCILRRHTDISQSVSNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLKDTVGREGRDRLLVQ LPLSLVYNSEDSAEYQFTGTYSTRLDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDESS >In-frame_TBC1D19_ENST00000511789_chr4_26641809_+_ANAPC4_ENST00000510092_chr4_25381996_+_862aa MLQEESDLSLIIAQIVQKLKGSNLYSQLERQAWGSWEKRILKSLNSMCTELSIPLARKRPVGEQKELLNKWNEMGTDEPDLSLFRPVYAP KDFLEVLLHRLASFHRVWSFPPNENTGKEVTCLAWRPDGKLLAFALADTKKIVLCDVEKPESLHSFSVEAPVSCMHWMEVTVESSVLTSF YNAEDESNLLLPKLPTLPKNYSNTSKIFSEENSDEIIKLLGDVRLNILVLGGSSGFIELYAYGMFKIARVTGIAGTCLALCLSSDLKSLS VVTEVSTNGASEVSYFQLETNLLYSFLPEVTRMARKFTHISALLQYINLSLTCMCEAWEEILMQMDSRLTKFVQEKNTTTSVQDEFMHLL LWGKASAELQTLLMNQLTVKGLKKLGQSIESSYSSIQKLVISHLQSGSESLLYHLSELKGMASWKQKYEPLGLDAAGIEEAITAVGSFIL KANELLQVIDSSMKNFKAFFRWLYVAMLRMTEDHVLPELNKVMTQKDITFVAEFLTEHFNEAPDLYNRKGKYFNVERVGQYLKDEDDDLV SPPNTEGNQWYDFLQNSSHLKESPLLFPYYPRKSLHFVKRRMENIIDQCLQKPADVIGKSMNQAICIPLYRDTRSEDSTRRLFKFPFLWN NKTSNLHYLLFTILEDSLYKMCILRRHTDISQSVSNGLIAIKFGSFTYATTEKVRRSIYSCLDAQFYDDETVTVVLKDTVGREGRDRLLV QLPLSLVYNSEDSAEYQFTGTYSTRLDEQCSAIPTRTMHFEKHWRLLESMKAQYVAGNGFRKVSCVLSSNLRHVRVFEMDIDDEWELDES |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TBC1D19_ENST00000264866_chr4_26641809_+_ANAPC4_ENST00000315368_chr4_25381996_+_2778nt ATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGCTGGAACGG CAGGCCTGGGCCAGTCTTCAGAGACCTGAGATTAAACTTGAATCACTGAAAGAAGATATTAAGGAATTCTTTAAAATATCAGGTTGGGAG AAGAAACTTCAGAATGCTGTTTATAGTGAACTGAGTGTGTTTCCTTTACCTAGTCATCCTGCTGCACCTCCTGAACATCTTAAAGAACCT TTGGTATACATGAGGAAAGCACAGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTATCCCACTG GCACGAAAGAGGCCAGTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCCTTTTCAGA CCTGTTTATGCACCTAAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAAATGAAAAT ACAGGAAAGGAGGTGACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTGTTTTGTGT GATGTAGAAAAACCTGAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAGAAAGCAGT GTTCTCACATCATTTTATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCAACACCTCA AAAATATTTAGTGAAGAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAAGCTCTGGA TTTATTGAGCTTTATGCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTATCAAGTGAT TTGAAATCATTATCAGTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGTTGTACTCT TTCTTACCTGAAGTAACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACATGTATGTGT GAAGCATGGGAAGAAATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGCAAGATGAG TTCATGCACTTGCTATTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGAAAAAGCTT GGCCAGTCTATAGAGTCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTATACCATTTG AGTGAATTGAAAGGAATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAACTGCTGTG GGTTCTTTTATACTCAAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGCTTTATGTG GCAATGTTGAGAATGACAGAAGACCATGTGCTTCCCGAGCTGAATAAGATGACTCAGAAAGATATCACATTTGTTGCTGAATTTCTTACT GAACATTTCAATGAGGCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGAAAGATGAAGAT GATGATCTTGTGTCACCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAAGTCCTTTGCTG TTTCCTTATTATCCTCGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGCCAGCAGATGTA ATTGGAAAATCGATGAATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGTTCAAATTTCCT TTTCTGTGGAATAATAAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCATCTTAAGGAGA CATACTGATATTTCTCAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAAAAGTCAGAAGA AGCATCTACAGTTGTTTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTGAAGGAAGAGAT AGACTCTTGGTCCAGCTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATTCTACAAGGCTA GATGAACAGTGTAGTGCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCACAGTATGTTGCT GGGAATGGTTTTCGAAAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATGATGAATGGGAG CTCGATGAGTCTTCAGATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAGAGGCAGAGAAC >In-frame_TBC1D19_ENST00000264866_chr4_26641809_+_ANAPC4_ENST00000510092_chr4_25381996_+_2781nt ATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGCTGGAACGG CAGGCCTGGGCCAGTCTTCAGAGACCTGAGATTAAACTTGAATCACTGAAAGAAGATATTAAGGAATTCTTTAAAATATCAGGTTGGGAG AAGAAACTTCAGAATGCTGTTTATAGTGAACTGAGTGTGTTTCCTTTACCTAGTCATCCTGCTGCACCTCCTGAACATCTTAAAGAACCT TTGGTATACATGAGGAAAGCACAGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTATCCCACTG GCACGAAAGAGGCCAGTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCCTTTTCAGA CCTGTTTATGCACCTAAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAAATGAAAAT ACAGGAAAGGAGGTGACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTGTTTTGTGT GATGTAGAAAAACCTGAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAGAAAGCAGT GTTCTCACATCATTTTATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCAACACCTCA AAAATATTTAGTGAAGAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAAGCTCTGGA TTTATTGAGCTTTATGCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTATCAAGTGAT TTGAAATCATTATCAGTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGTTGTACTCT TTCTTACCTGAAGTAACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACATGTATGTGT GAAGCATGGGAAGAAATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGCAAGATGAG TTCATGCACTTGCTATTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGAAAAAGCTT GGCCAGTCTATAGAGTCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTATACCATTTG AGTGAATTGAAAGGAATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAACTGCTGTG GGTTCTTTTATACTCAAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGCTTTATGTG GCAATGTTGAGAATGACAGAAGACCATGTGCTTCCCGAGCTGAATAAGGTAATGACTCAGAAAGATATCACATTTGTTGCTGAATTTCTT ACTGAACATTTCAATGAGGCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGAAAGATGAA GATGATGATCTTGTGTCACCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAAGTCCTTTG CTGTTTCCTTATTATCCTCGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGCCAGCAGAT GTAATTGGAAAATCGATGAATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGTTCAAATTT CCTTTTCTGTGGAATAATAAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCATCTTAAGG AGACATACTGATATTTCTCAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAAAAGTCAGA AGAAGCATCTACAGTTGTTTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTGAAGGAAGA GATAGACTCTTGGTCCAGCTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATTCTACAAGG CTAGATGAACAGTGTAGTGCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCACAGTATGTT GCTGGGAATGGTTTTCGAAAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATGATGAATGG GAGCTCGATGAGTCTTCAGATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAGAGGCAGAG >In-frame_TBC1D19_ENST00000511789_chr4_26641809_+_ANAPC4_ENST00000315368_chr4_25381996_+_2583nt ATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGCTGGAACGG CAGGCCTGGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTATCCCACTGGCACGAAAGAGGCCA GTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCCTTTTCAGACCTGTTTATGCACCT AAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAAATGAAAATACAGGAAAGGAGGTG ACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTGTTTTGTGTGATGTAGAAAAACCT GAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAGAAAGCAGTGTTCTCACATCATTT TATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCAACACCTCAAAAATATTTAGTGAA GAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAAGCTCTGGATTTATTGAGCTTTAT GCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTATCAAGTGATTTGAAATCATTATCA GTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGTTGTACTCTTTCTTACCTGAAGTA ACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACATGTATGTGTGAAGCATGGGAAGAA ATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGCAAGATGAGTTCATGCACTTGCTA TTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGAAAAAGCTTGGCCAGTCTATAGAG TCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTATACCATTTGAGTGAATTGAAAGGA ATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAACTGCTGTGGGTTCTTTTATACTC AAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGCTTTATGTGGCAATGTTGAGAATG ACAGAAGACCATGTGCTTCCCGAGCTGAATAAGATGACTCAGAAAGATATCACATTTGTTGCTGAATTTCTTACTGAACATTTCAATGAG GCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGAAAGATGAAGATGATGATCTTGTGTCA CCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAAGTCCTTTGCTGTTTCCTTATTATCCT CGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGCCAGCAGATGTAATTGGAAAATCGATG AATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGTTCAAATTTCCTTTTCTGTGGAATAAT AAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCATCTTAAGGAGACATACTGATATTTCT CAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAAAAGTCAGAAGAAGCATCTACAGTTGT TTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTGAAGGAAGAGATAGACTCTTGGTCCAG CTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATTCTACAAGGCTAGATGAACAGTGTAGT GCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCACAGTATGTTGCTGGGAATGGTTTTCGA AAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATGATGAATGGGAGCTCGATGAGTCTTCA GATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAGAGGCAGAGAACCAACAAGCTGGTGCT >In-frame_TBC1D19_ENST00000511789_chr4_26641809_+_ANAPC4_ENST00000510092_chr4_25381996_+_2586nt ATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGCTGGAACGG CAGGCCTGGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTATCCCACTGGCACGAAAGAGGCCA GTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCCTTTTCAGACCTGTTTATGCACCT AAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAAATGAAAATACAGGAAAGGAGGTG ACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTGTTTTGTGTGATGTAGAAAAACCT GAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAGAAAGCAGTGTTCTCACATCATTT TATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCAACACCTCAAAAATATTTAGTGAA GAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAAGCTCTGGATTTATTGAGCTTTAT GCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTATCAAGTGATTTGAAATCATTATCA GTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGTTGTACTCTTTCTTACCTGAAGTA ACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACATGTATGTGTGAAGCATGGGAAGAA ATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGCAAGATGAGTTCATGCACTTGCTA TTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGAAAAAGCTTGGCCAGTCTATAGAG TCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTATACCATTTGAGTGAATTGAAAGGA ATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAACTGCTGTGGGTTCTTTTATACTC AAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGCTTTATGTGGCAATGTTGAGAATG ACAGAAGACCATGTGCTTCCCGAGCTGAATAAGGTAATGACTCAGAAAGATATCACATTTGTTGCTGAATTTCTTACTGAACATTTCAAT GAGGCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGAAAGATGAAGATGATGATCTTGTG TCACCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAAGTCCTTTGCTGTTTCCTTATTAT CCTCGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGCCAGCAGATGTAATTGGAAAATCG ATGAATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGTTCAAATTTCCTTTTCTGTGGAAT AATAAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCATCTTAAGGAGACATACTGATATT TCTCAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAAAAGTCAGAAGAAGCATCTACAGT TGTTTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTGAAGGAAGAGATAGACTCTTGGTC CAGCTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATTCTACAAGGCTAGATGAACAGTGT AGTGCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCACAGTATGTTGCTGGGAATGGTTTT CGAAAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATGATGAATGGGAGCTCGATGAGTCT TCAGATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAGAGGCAGAGAACCAACAAGCTGGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TBC1D19_ENST00000264866_chr4_26641809_+_ANAPC4_ENST00000315368_chr4_25381996_+_3172nt TTTCAACCATAGACAAGGCAGGAACAACGGTGTGAAAAGCGTCCTCCCCGCCCCGGTCTTTTTCCGCCGGCGGAACGCAGATGCTGTGGC CTTCAGGCGCTGAGGGGACCAGAGAGGGACGGACACAAGGCTCGGCAGTTGCCTGGTAACGCCCGCTGGAGGAGTCCCAGTGTAATAAGG TCCCGGAGAAGTGTCACTGGCCCTGAGTGGGACCCGGTAGCCCGTTCGCTCCGCGCCGGCGGCCTGTCCCCGCGGCTTGGCGGGCTAGGG CAGGGGAAATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGC TGGAACGGCAGGCCTGGGCCAGTCTTCAGAGACCTGAGATTAAACTTGAATCACTGAAAGAAGATATTAAGGAATTCTTTAAAATATCAG GTTGGGAGAAGAAACTTCAGAATGCTGTTTATAGTGAACTGAGTGTGTTTCCTTTACCTAGTCATCCTGCTGCACCTCCTGAACATCTTA AAGAACCTTTGGTATACATGAGGAAAGCACAGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTA TCCCACTGGCACGAAAGAGGCCAGTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCC TTTTCAGACCTGTTTATGCACCTAAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAA ATGAAAATACAGGAAAGGAGGTGACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTG TTTTGTGTGATGTAGAAAAACCTGAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAG AAAGCAGTGTTCTCACATCATTTTATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCA ACACCTCAAAAATATTTAGTGAAGAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAA GCTCTGGATTTATTGAGCTTTATGCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTAT CAAGTGATTTGAAATCATTATCAGTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGT TGTACTCTTTCTTACCTGAAGTAACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACAT GTATGTGTGAAGCATGGGAAGAAATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGC AAGATGAGTTCATGCACTTGCTATTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGA AAAAGCTTGGCCAGTCTATAGAGTCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTAT ACCATTTGAGTGAATTGAAAGGAATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAA CTGCTGTGGGTTCTTTTATACTCAAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGC TTTATGTGGCAATGTTGAGAATGACAGAAGACCATGTGCTTCCCGAGCTGAATAAGATGACTCAGAAAGATATCACATTTGTTGCTGAAT TTCTTACTGAACATTTCAATGAGGCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGAAAG ATGAAGATGATGATCTTGTGTCACCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAAGTC CTTTGCTGTTTCCTTATTATCCTCGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGCCAG CAGATGTAATTGGAAAATCGATGAATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGTTCA AATTTCCTTTTCTGTGGAATAATAAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCATCT TAAGGAGACATACTGATATTTCTCAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAAAAG TCAGAAGAAGCATCTACAGTTGTTTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTGAAG GAAGAGATAGACTCTTGGTCCAGCTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATTCTA CAAGGCTAGATGAACAGTGTAGTGCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCACAGT ATGTTGCTGGGAATGGTTTTCGAAAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATGATG AATGGGAGCTCGATGAGTCTTCAGATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAGAGG CAGAGAACCAACAAGCTGGTGCTGCCGCTTTAGCTCCAGAGATAGTCATTAAAGTGGAAAAACTTGACCCTGAGCTAGACTCCTAATCTA GCTTGCCATTATTGTGTGTGTAATTATGGCCAAAAGGACATAGGAGATGGACTAAGATGTCTTGGACCACCTTTGTGTAACAAAGAAATA >In-frame_TBC1D19_ENST00000264866_chr4_26641809_+_ANAPC4_ENST00000510092_chr4_25381996_+_3166nt TTTCAACCATAGACAAGGCAGGAACAACGGTGTGAAAAGCGTCCTCCCCGCCCCGGTCTTTTTCCGCCGGCGGAACGCAGATGCTGTGGC CTTCAGGCGCTGAGGGGACCAGAGAGGGACGGACACAAGGCTCGGCAGTTGCCTGGTAACGCCCGCTGGAGGAGTCCCAGTGTAATAAGG TCCCGGAGAAGTGTCACTGGCCCTGAGTGGGACCCGGTAGCCCGTTCGCTCCGCGCCGGCGGCCTGTCCCCGCGGCTTGGCGGGCTAGGG CAGGGGAAATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGC TGGAACGGCAGGCCTGGGCCAGTCTTCAGAGACCTGAGATTAAACTTGAATCACTGAAAGAAGATATTAAGGAATTCTTTAAAATATCAG GTTGGGAGAAGAAACTTCAGAATGCTGTTTATAGTGAACTGAGTGTGTTTCCTTTACCTAGTCATCCTGCTGCACCTCCTGAACATCTTA AAGAACCTTTGGTATACATGAGGAAAGCACAGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTA TCCCACTGGCACGAAAGAGGCCAGTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCC TTTTCAGACCTGTTTATGCACCTAAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAA ATGAAAATACAGGAAAGGAGGTGACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTG TTTTGTGTGATGTAGAAAAACCTGAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAG AAAGCAGTGTTCTCACATCATTTTATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCA ACACCTCAAAAATATTTAGTGAAGAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAA GCTCTGGATTTATTGAGCTTTATGCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTAT CAAGTGATTTGAAATCATTATCAGTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGT TGTACTCTTTCTTACCTGAAGTAACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACAT GTATGTGTGAAGCATGGGAAGAAATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGC AAGATGAGTTCATGCACTTGCTATTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGA AAAAGCTTGGCCAGTCTATAGAGTCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTAT ACCATTTGAGTGAATTGAAAGGAATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAA CTGCTGTGGGTTCTTTTATACTCAAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGC TTTATGTGGCAATGTTGAGAATGACAGAAGACCATGTGCTTCCCGAGCTGAATAAGGTAATGACTCAGAAAGATATCACATTTGTTGCTG AATTTCTTACTGAACATTTCAATGAGGCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGA AAGATGAAGATGATGATCTTGTGTCACCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAA GTCCTTTGCTGTTTCCTTATTATCCTCGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGC CAGCAGATGTAATTGGAAAATCGATGAATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGT TCAAATTTCCTTTTCTGTGGAATAATAAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCA TCTTAAGGAGACATACTGATATTTCTCAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAA AAGTCAGAAGAAGCATCTACAGTTGTTTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTG AAGGAAGAGATAGACTCTTGGTCCAGCTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATT CTACAAGGCTAGATGAACAGTGTAGTGCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCAC AGTATGTTGCTGGGAATGGTTTTCGAAAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATG ATGAATGGGAGCTCGATGAGTCTTCAGATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAG AGGCAGAGAACCAACAAGCTGGTGCTGCCGCTTTAGCTCCAGAGATAGTCATTAAAGTGGAAAAACTTGACCCTGAGCTAGACTCCTAAT CTAGCTTGCCATTATTGTGTGTGTAATTATGGCCAAAAGGACATAGGAGATGGACTAAGATGTCTTGGACCACCTTTGTGTAACAAAGAA >In-frame_TBC1D19_ENST00000511789_chr4_26641809_+_ANAPC4_ENST00000315368_chr4_25381996_+_2699nt ATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGCTGGAACGG CAGGCCTGGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTATCCCACTGGCACGAAAGAGGCCA GTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCCTTTTCAGACCTGTTTATGCACCT AAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAAATGAAAATACAGGAAAGGAGGTG ACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTGTTTTGTGTGATGTAGAAAAACCT GAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAGAAAGCAGTGTTCTCACATCATTT TATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCAACACCTCAAAAATATTTAGTGAA GAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAAGCTCTGGATTTATTGAGCTTTAT GCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTATCAAGTGATTTGAAATCATTATCA GTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGTTGTACTCTTTCTTACCTGAAGTA ACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACATGTATGTGTGAAGCATGGGAAGAA ATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGCAAGATGAGTTCATGCACTTGCTA TTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGAAAAAGCTTGGCCAGTCTATAGAG TCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTATACCATTTGAGTGAATTGAAAGGA ATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAACTGCTGTGGGTTCTTTTATACTC AAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGCTTTATGTGGCAATGTTGAGAATG ACAGAAGACCATGTGCTTCCCGAGCTGAATAAGATGACTCAGAAAGATATCACATTTGTTGCTGAATTTCTTACTGAACATTTCAATGAG GCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGAAAGATGAAGATGATGATCTTGTGTCA CCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAAGTCCTTTGCTGTTTCCTTATTATCCT CGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGCCAGCAGATGTAATTGGAAAATCGATG AATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGTTCAAATTTCCTTTTCTGTGGAATAAT AAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCATCTTAAGGAGACATACTGATATTTCT CAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAAAAGTCAGAAGAAGCATCTACAGTTGT TTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTGAAGGAAGAGATAGACTCTTGGTCCAG CTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATTCTACAAGGCTAGATGAACAGTGTAGT GCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCACAGTATGTTGCTGGGAATGGTTTTCGA AAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATGATGAATGGGAGCTCGATGAGTCTTCA GATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAGAGGCAGAGAACCAACAAGCTGGTGCT GCCGCTTTAGCTCCAGAGATAGTCATTAAAGTGGAAAAACTTGACCCTGAGCTAGACTCCTAATCTAGCTTGCCATTATTGTGTGTGTAA >In-frame_TBC1D19_ENST00000511789_chr4_26641809_+_ANAPC4_ENST00000510092_chr4_25381996_+_2693nt ATGTTGCAGGAGGAGTCGGACCTCTCTCTCATTATTGCCCAGATAGTCCAAAAGCTCAAGGGCTCCAATTTGTACTCTCAGCTGGAACGG CAGGCCTGGGGAAGTTGGGAAAAAAGAATTTTGAAGAGTTTAAATAGTATGTGCACTGAACTGAGTATCCCACTGGCACGAAAGAGGCCA GTTGGAGAACAGAAAGAACTTCTTAATAAATGGAATGAAATGGGAACTGATGAACCAGATTTAAGCCTTTTCAGACCTGTTTATGCACCT AAGGATTTTCTTGAGGTTTTACTTCATCGACTGGCAAGTTTTCATCGAGTTTGGAGTTTTCCACCAAATGAAAATACAGGAAAGGAGGTG ACGTGTCTGGCATGGAGACCAGATGGCAAACTTTTGGCCTTTGCTCTTGCTGATACCAAGAAAATTGTTTTGTGTGATGTAGAAAAACCT GAGAGCTTACACTCTTTTTCTGTGGAGGCTCCAGTTTCCTGTATGCATTGGATGGAAGTGACAGTAGAAAGCAGTGTTCTCACATCATTT TATAATGCTGAGGATGAATCAAATCTTCTCTTACCTAAACTACCTACACTGCCAAAAAACTATAGCAACACCTCAAAAATATTTAGTGAA GAAAATTCTGATGAAATTATTAAGCTCTTGGGAGACGTCAGGCTTAATATTCTCGTCCTTGGAGGAAGCTCTGGATTTATTGAGCTTTAT GCTTATGGAATGTTTAAAATTGCTCGAGTCACAGGGATTGCTGGTACTTGTCTTGCATTATGTTTATCAAGTGATTTGAAATCATTATCA GTGGTCACAGAAGTCTCTACCAATGGTGCTTCAGAAGTTTCATACTTTCAGCTTGAAACTAATCTGTTGTACTCTTTCTTACCTGAAGTA ACTCGGATGGCCAGAAAGTTTACTCATATTTCAGCTCTGTTACAGTATATAAATTTGTCACTAACATGTATGTGTGAAGCATGGGAAGAA ATACTAATGCAGATGGATTCTCGTCTCACCAAGTTTGTGCAGGAAAAGAACACAACCACATCAGTGCAAGATGAGTTCATGCACTTGCTA TTATGGGGGAAAGCAAGTGCTGAACTTCAGACTCTCTTGATGAATCAGTTAACAGTAAAGGGCTTGAAAAAGCTTGGCCAGTCTATAGAG TCATCATACTCCAGTATACAAAAATTGGTCATAAGTCATTTACAGAGTGGCTCGGAGTCTTTATTATACCATTTGAGTGAATTGAAAGGA ATGGCTTCATGGAAGCAAAAATATGAACCTCTTGGACTAGATGCTGCAGGAATCGAAGAAGCTATAACTGCTGTGGGTTCTTTTATACTC AAGGCAAATGAACTTCTTCAAGTTATAGATAGTAGTATGAAAAACTTCAAAGCATTTTTTCGGTGGCTTTATGTGGCAATGTTGAGAATG ACAGAAGACCATGTGCTTCCCGAGCTGAATAAGGTAATGACTCAGAAAGATATCACATTTGTTGCTGAATTTCTTACTGAACATTTCAAT GAGGCTCCAGACCTTTATAATCGAAAAGGAAAATACTTTAACGTTGAAAGAGTTGGTCAGTACTTGAAAGATGAAGATGATGATCTTGTG TCACCCCCTAACACAGAAGGAAACCAGTGGTATGACTTTCTTCAAAATAGCAGCCACCTTAAAGAAAGTCCTTTGCTGTTTCCTTATTAT CCTCGAAAATCATTGCATTTTGTGAAAAGGCGGATGGAGAATATTATTGATCAGTGTTTGCAAAAGCCAGCAGATGTAATTGGAAAATCG ATGAATCAAGCAATCTGTATTCCATTGTATAGAGATACCAGAAGTGAGGATTCTACACGTAGATTGTTCAAATTTCCTTTTCTGTGGAAT AATAAAACTTCAAATCTACATTATCTTCTTTTTACTATTCTAGAAGATTCACTTTATAAAATGTGCATCTTAAGGAGACATACTGATATT TCTCAATCTGTGAGTAATGGACTAATTGCTATTAAATTTGGGAGCTTTACATATGCCACAACAGAAAAAGTCAGAAGAAGCATCTACAGT TGTTTAGATGCACAGTTTTATGATGATGAAACTGTAACAGTAGTTCTTAAAGACACTGTAGGACGTGAAGGAAGAGATAGACTCTTGGTC CAGCTGCCTTTGTCTTTAGTATATAACAGTGAAGATTCTGCAGAATATCAGTTCACTGGGACTTATTCTACAAGGCTAGATGAACAGTGT AGTGCTATTCCCACCCGTACCATGCATTTTGAGAAGCACTGGAGATTACTGGAAAGTATGAAAGCACAGTATGTTGCTGGGAATGGTTTT CGAAAAGTGTCCTGTGTGTTAAGCTCAAATCTTCGTCATGTGAGAGTATTTGAAATGGACATAGATGATGAATGGGAGCTCGATGAGTCT TCAGATGAAGAGGAGGAGGCCAGTAATAAGCCTGTAAAAATAAAGGAAGAAGTGTTGTCGGAGTCAGAGGCAGAGAACCAACAAGCTGGT GCTGCCGCTTTAGCTCCAGAGATAGTCATTAAAGTGGAAAAACTTGACCCTGAGCTAGACTCCTAATCTAGCTTGCCATTATTGTGTGTG |
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FusionGenePPI for TBC1D19_ANAPC4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TBC1D19 | PPP1CC, MAGEA12, TTLL1, CEP135, LRRC49, NICN1 | ANAPC4 | CDC27, ANAPC1, ANAPC15, CDC16, ANAPC7, ANAPC11, BUB1B, RAD21, CDC20, BUB3, MAD2L1, SH3KBP1, CCNB1, ANAPC4, CCNA2, COPS2, FBXO5, ANAPC5, CDC23, ANAPC2, ANAPC10, ANAPC13, MDC1, PAXIP1, TP53BP1, TRIM33, PTEN, SOX2, PHF8, HECW2, ANAPC16, CDC26, FZR1, DCPS, UBE2S, NEK2, KIF18A, PENK, MAGIX, RRM2, TTLL1, KRAS, XPO1, CFAP97, CDK1, USP37, NANOG, POU5F1, PSMD8, C16orf87, ANO6, GPR156, NUP98, HOXD13, LNP1, HHEX |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TBC1D19_ANAPC4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TBC1D19_ANAPC4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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