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Fusion gene ID: 37025 |
FusionGeneSummary for TAB2_PPP1R14C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TAB2_PPP1R14C | Fusion gene ID: 37025 | Hgene | Tgene | Gene symbol | TAB2 | PPP1R14C | Gene ID | 23118 | 81706 |
| Gene name | TGF-beta activated kinase 1 (MAP3K7) binding protein 2 | protein phosphatase 1 regulatory inhibitor subunit 14C | |
| Synonyms | CHTD2|MAP3K7IP2|TAB-2 | CPI17-like|KEPI|NY-BR-81 | |
| Cytomap | 6q25.1 | 6q25.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | TGF-beta-activated kinase 1 and MAP3K7-binding protein 2TAK1-binding protein 2mitogen-activated protein kinase kinase kinase 7-interacting protein 2 | protein phosphatase 1 regulatory subunit 14CPKC-potentiated PP1 inhibitory proteinkinase C-enhanced PP1 inhibitorkinase-enhanced PP1 inhibitorserologically defined breast cancer antigen NY-BR-81 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9NYJ8 | Q8TAE6 | |
| Ensembl transtripts involved in fusion gene | ENST00000536230, ENST00000392282, ENST00000538427, ENST00000367456, ENST00000461481, ENST00000286332, | ENST00000361131, | |
| Fusion gene scores | * DoF score | 11 X 9 X 5=495 | 3 X 2 X 3=18 |
| # samples | 10 | 3 | |
| ** MAII score | log2(10/495*10)=-2.30742852519225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: TAB2 [Title/Abstract] AND PPP1R14C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | TAB2 | GO:0045860 | positive regulation of protein kinase activity | 11460167 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BLCA | TCGA-ZF-AA51-01A | TAB2 | chr6 | 149718900 | + | PPP1R14C | chr6 | 150535880 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000536230 | ENST00000361131 | TAB2 | chr6 | 149718900 | + | PPP1R14C | chr6 | 150535880 | + |
| intron-3CDS | ENST00000392282 | ENST00000361131 | TAB2 | chr6 | 149718900 | + | PPP1R14C | chr6 | 150535880 | + |
| In-frame | ENST00000538427 | ENST00000361131 | TAB2 | chr6 | 149718900 | + | PPP1R14C | chr6 | 150535880 | + |
| In-frame | ENST00000367456 | ENST00000361131 | TAB2 | chr6 | 149718900 | + | PPP1R14C | chr6 | 150535880 | + |
| intron-3CDS | ENST00000461481 | ENST00000361131 | TAB2 | chr6 | 149718900 | + | PPP1R14C | chr6 | 150535880 | + |
| In-frame | ENST00000286332 | ENST00000361131 | TAB2 | chr6 | 149718900 | + | PPP1R14C | chr6 | 150535880 | + |
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FusionProtFeatures for TAB2_PPP1R14C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TAB2 | PPP1R14C |
| Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylationof MAP3K7 at 'Thr-187'. Involved in heart development.{ECO:0000269|PubMed:10882101, ECO:0000269|PubMed:11460167,ECO:0000269|PubMed:20493459}. | Inhibitor of the PP1 regulatory subunit PPP1CA. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TAB2 | chr6:149718900 | chr6:150535880 | ENST00000286332 | + | 3 | 6 | 8_51 | 588 | 694 | Domain | CUE |
| Hgene | TAB2 | chr6:149718900 | chr6:150535880 | ENST00000367456 | + | 5 | 8 | 8_51 | 588 | 694 | Domain | CUE |
| Hgene | TAB2 | chr6:149718900 | chr6:150535880 | ENST00000538427 | + | 5 | 8 | 8_51 | 588 | 694 | Domain | CUE |
| Tgene | >PPP1R14C | chr6:149718900 | chr6:150535880 | ENST00000361131 | + | 0 | 4 | 102_105 | 102 | 166 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000286332 | + | 3 | 6 | 532_619 | 588 | 694 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000367456 | + | 5 | 8 | 532_619 | 588 | 694 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000392282 | + | 1 | 4 | 532_619 | -60 | 537 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000538427 | + | 5 | 8 | 532_619 | 588 | 694 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000392282 | + | 1 | 4 | 8_51 | -60 | 537 | Domain | CUE |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000286332 | + | 3 | 6 | 663_693 | 588 | 694 | Zinc finger | RanBP2-type |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000367456 | + | 5 | 8 | 663_693 | 588 | 694 | Zinc finger | RanBP2-type |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000392282 | + | 1 | 4 | 663_693 | -60 | 537 | Zinc finger | RanBP2-type |
| Hgene | >TAB2 | chr6:149718900 | chr6:150535880 | ENST00000538427 | + | 5 | 8 | 663_693 | 588 | 694 | Zinc finger | RanBP2-type |
| Tgene | PPP1R14C | chr6:149718900 | chr6:150535880 | ENST00000361131 | + | 0 | 4 | 51_56 | 102 | 166 | Compositional bias | Note=Poly-Ala |
| Tgene | PPP1R14C | chr6:149718900 | chr6:150535880 | ENST00000361131 | + | 0 | 4 | 58_64 | 102 | 166 | Compositional bias | Note=Poly-Gln |
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FusionGeneSequence for TAB2_PPP1R14C |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TAB2_ENST00000536230_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_620aa MQNNNNLDACCAVLSQESTRYLYGEGDLNFSDDSGISGLRNHMTSLNLDLQSQNIYHHGREGSRMNGSRTLTHSISDGQLQGGQSNSELF QQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVTLAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNS IYIRPYITTPGGTTRQTQQHSGWVSQFNPMNPQQVYQPSQPGPWTTCPASNPLSHTSSQQPNQQGHQTSHVYMPISSPTTSQPPTIHSSG SSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTLNRNQPTVYIAASPPNTDELMSRSQPKVYISAN AATGDEQVMRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATSPRVVVTQPNTKYTFKITVSPNKPPAVSPGVVS PTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQKARMERLQRELEIQKKKLDKLKSEVNEMENNL >In-frame_TAB2_ENST00000538427_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_652aa MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDLNFSDDSGISGLRNHMTSLNLDLQSQNIYHH GREGSRMNGSRTLTHSISDGQLQGGQSNSELFQQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVT LAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQFNPMNPQQVYQPSQPGPWTTCPASNPLSHTSS QQPNQQGHQTSHVYMPISSPTTSQPPTIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTL NRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATS PRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQ KARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKPTEEFI >In-frame_TAB2_ENST00000367456_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_652aa MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDLNFSDDSGISGLRNHMTSLNLDLQSQNIYHH GREGSRMNGSRTLTHSISDGQLQGGQSNSELFQQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVT LAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQFNPMNPQQVYQPSQPGPWTTCPASNPLSHTSS QQPNQQGHQTSHVYMPISSPTTSQPPTIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTL NRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATS PRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQ KARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKPTEEFI >In-frame_TAB2_ENST00000286332_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_652aa MAQGSHQIDFQVLHDLRQKFPEVPEVVVSRCMLQNNNNLDACCAVLSQESTRYLYGEGDLNFSDDSGISGLRNHMTSLNLDLQSQNIYHH GREGSRMNGSRTLTHSISDGQLQGGQSNSELFQQEPQTAPAQVPQGFNVFGMSSSSGASNSAPHLGFHLGSKGTSSLSQQTPRFNPIMVT LAPNIQTGRNTPTSLHIHGVPPPVLNSPQGNSIYIRPYITTPGGTTRQTQQHSGWVSQFNPMNPQQVYQPSQPGPWTTCPASNPLSHTSS QQPNQQGHQTSHVYMPISSPTTSQPPTIHSSGSSQSSAHSQYNIQNISTGPRKNQIEIKLEPPQRNNSSKLRSSGPRTSSTSSSVNSQTL NRNQPTVYIAASPPNTDELMSRSQPKVYISANAATGDEQVMRNQPTLFISTNSGASAASRNMSGQVSMGPAFIHHHPPKSRAIGNNSATS PRVVVTQPNTKYTFKITVSPNKPPAVSPGVVSPTFELTNLLNHPDHYVETENIQHLTDPTLAHVDRISETRKLSMGSDDAAYTQALLVHQ KARMERLQRELEIQKKKLDKLKSEVNEMENNLTRRRLKRSNSISQIPSEEEMPEVEIDIDDLLDADSDEERASKLQEALVDCYKPTEEFI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TAB2_ENST00000536230_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_1860nt ATGCAGAATAATAATAACCTGGATGCCTGCTGTGCTGTTCTCTCTCAGGAGAGTACAAGATATCTTTATGGTGAAGGAGACTTGAATTTT TCAGATGATTCTGGAATTTCTGGTCTACGCAATCACATGACTTCTCTCAACTTGGACTTGCAATCACAGAACATTTACCACCATGGAAGA GAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCACAGCATTAGTGATGGACAACTTCAAGGTGGCCAGTCCAATAGTGAACTATTT CAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCAAGGCTTTAATGTTTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAATTCAGCA CCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATCTAGCCTTTCTCAACAAACTCCCAGATTTAATCCCATTATGGTAACTTTAGCC CCAAATATCCAGACTGGTCGTAATACTCCTACATCTTTGCACATACATGGTGTACCTCCACCTGTACTTAACAGTCCACAGGGAAATTCT ATCTATATTAGGCCTTACATTACAACTCCTGGTGGTACAACTCGACAGACACAACAGCATTCTGGCTGGGTATCTCAGTTTAATCCCATG AACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCCCTGGACTACTTGTCCTGCATCTAATCCTCTGTCACATACCTCATCTCAACAG CCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACATGCCAATCAGTTCACCTACTACTTCACAACCACCAACCATTCATTCATCTGGT AGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCAGAATATTTCAACAGGACCTCGAAAAAACCAGATTGAAATCAAACTTGAACCC CCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGGACCTCGAACCTCCAGCACTTCCTCTTCAGTCAATAGCCAGACCTTAAACAGA AATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAATACGGATGAGCTGATGTCCCGTAGTCAACCTAAGGTCTATATTTCAGCGAAT GCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCCCACACTCTTCATATCCACAAACTCTGGAGCATCTGCTGCCTCCAGGAACATG TCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCACCATCCTCCCAAAAGTCGAGCAATAGGCAATAACTCTGCAACCTCTCCTCGA GTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAAAATTACAGTCTCTCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTGGTGTCC CCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGATCATTATGTAGAAACCGAGAATATTCAGCACCTCACGGACCCTACATTAGCA CATGTGGATAGAATAAGTGAAACACGGAAACTGAGTATGGGATCTGATGATGCTGCCTACACACAAGCTCTTTTGGTACACCAGAAGGCC AGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAAGAAAAAGCTGGATAAATTAAAATCTGAGGTTAATGAAATGGAAAATAATCTA ACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCAGATACCTTCCGAAGAAGAAATGCCAGAGGTAGAAATTGACATTGATGATCTT CTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATTACAGGAAGCTCTTGTAGACTGCTACAAACCAACAGAGGAATTTATCAAAGAG >In-frame_TAB2_ENST00000538427_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_1956nt ATGGCCCAAGGAAGCCACCAAATTGATTTTCAGGTTTTACATGACCTGCGACAAAAATTCCCTGAAGTACCTGAAGTTGTTGTATCCAGG TGCATGTTACAGAATAATAATAACCTGGATGCCTGCTGTGCTGTTCTCTCTCAGGAGAGTACAAGATATCTTTATGGTGAAGGAGACTTG AATTTTTCAGATGATTCTGGAATTTCTGGTCTACGCAATCACATGACTTCTCTCAACTTGGACTTGCAATCACAGAACATTTACCACCAT GGAAGAGAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCACAGCATTAGTGATGGACAACTTCAAGGTGGCCAGTCCAATAGTGAA CTATTTCAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCAAGGCTTTAATGTTTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAAT TCAGCACCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATCTAGCCTTTCTCAACAAACTCCCAGATTTAATCCCATTATGGTAACT TTAGCCCCAAATATCCAGACTGGTCGTAATACTCCTACATCTTTGCACATACATGGTGTACCTCCACCTGTACTTAACAGTCCACAGGGA AATTCTATCTATATTAGGCCTTACATTACAACTCCTGGTGGTACAACTCGACAGACACAACAGCATTCTGGCTGGGTATCTCAGTTTAAT CCCATGAACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCCCTGGACTACTTGTCCTGCATCTAATCCTCTGTCACATACCTCATCT CAACAGCCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACATGCCAATCAGTTCACCTACTACTTCACAACCACCAACCATTCATTCA TCTGGTAGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCAGAATATTTCAACAGGACCTCGAAAAAACCAGATTGAAATCAAACTT GAACCCCCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGGACCTCGAACCTCCAGCACTTCCTCTTCAGTCAATAGCCAGACCTTA AACAGAAATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAATACGGATGAGCTGATGTCCCGTAGTCAACCTAAGGTCTATATTTCA GCGAATGCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCCCACACTCTTCATATCCACAAACTCTGGAGCATCTGCTGCCTCCAGG AACATGTCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCACCATCCTCCCAAAAGTCGAGCAATAGGCAATAACTCTGCAACCTCT CCTCGAGTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAAAATTACAGTCTCTCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTG GTGTCCCCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGATCATTATGTAGAAACCGAGAATATTCAGCACCTCACGGACCCTACA TTAGCACATGTGGATAGAATAAGTGAAACACGGAAACTGAGTATGGGATCTGATGATGCTGCCTACACACAAGCTCTTTTGGTACACCAG AAGGCCAGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAAGAAAAAGCTGGATAAATTAAAATCTGAGGTTAATGAAATGGAAAAT AATCTAACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCAGATACCTTCCGAAGAAGAAATGCCAGAGGTAGAAATTGACATTGAT GATCTTCTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATTACAGGAAGCTCTTGTAGACTGCTACAAACCAACAGAGGAATTTATC >In-frame_TAB2_ENST00000367456_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_1956nt ATGGCCCAAGGAAGCCACCAAATTGATTTTCAGGTTTTACATGACCTGCGACAAAAATTCCCTGAAGTACCTGAAGTTGTTGTATCCAGG TGCATGTTACAGAATAATAATAACCTGGATGCCTGCTGTGCTGTTCTCTCTCAGGAGAGTACAAGATATCTTTATGGTGAAGGAGACTTG AATTTTTCAGATGATTCTGGAATTTCTGGTCTACGCAATCACATGACTTCTCTCAACTTGGACTTGCAATCACAGAACATTTACCACCAT GGAAGAGAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCACAGCATTAGTGATGGACAACTTCAAGGTGGCCAGTCCAATAGTGAA CTATTTCAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCAAGGCTTTAATGTTTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAAT TCAGCACCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATCTAGCCTTTCTCAACAAACTCCCAGATTTAATCCCATTATGGTAACT TTAGCCCCAAATATCCAGACTGGTCGTAATACTCCTACATCTTTGCACATACATGGTGTACCTCCACCTGTACTTAACAGTCCACAGGGA AATTCTATCTATATTAGGCCTTACATTACAACTCCTGGTGGTACAACTCGACAGACACAACAGCATTCTGGCTGGGTATCTCAGTTTAAT CCCATGAACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCCCTGGACTACTTGTCCTGCATCTAATCCTCTGTCACATACCTCATCT CAACAGCCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACATGCCAATCAGTTCACCTACTACTTCACAACCACCAACCATTCATTCA TCTGGTAGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCAGAATATTTCAACAGGACCTCGAAAAAACCAGATTGAAATCAAACTT GAACCCCCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGGACCTCGAACCTCCAGCACTTCCTCTTCAGTCAATAGCCAGACCTTA AACAGAAATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAATACGGATGAGCTGATGTCCCGTAGTCAACCTAAGGTCTATATTTCA GCGAATGCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCCCACACTCTTCATATCCACAAACTCTGGAGCATCTGCTGCCTCCAGG AACATGTCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCACCATCCTCCCAAAAGTCGAGCAATAGGCAATAACTCTGCAACCTCT CCTCGAGTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAAAATTACAGTCTCTCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTG GTGTCCCCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGATCATTATGTAGAAACCGAGAATATTCAGCACCTCACGGACCCTACA TTAGCACATGTGGATAGAATAAGTGAAACACGGAAACTGAGTATGGGATCTGATGATGCTGCCTACACACAAGCTCTTTTGGTACACCAG AAGGCCAGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAAGAAAAAGCTGGATAAATTAAAATCTGAGGTTAATGAAATGGAAAAT AATCTAACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCAGATACCTTCCGAAGAAGAAATGCCAGAGGTAGAAATTGACATTGAT GATCTTCTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATTACAGGAAGCTCTTGTAGACTGCTACAAACCAACAGAGGAATTTATC >In-frame_TAB2_ENST00000286332_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_1956nt ATGGCCCAAGGAAGCCACCAAATTGATTTTCAGGTTTTACATGACCTGCGACAAAAATTCCCTGAAGTACCTGAAGTTGTTGTATCCAGG TGCATGTTACAGAATAATAATAACCTGGATGCCTGCTGTGCTGTTCTCTCTCAGGAGAGTACAAGATATCTTTATGGTGAAGGAGACTTG AATTTTTCAGATGATTCTGGAATTTCTGGTCTACGCAATCACATGACTTCTCTCAACTTGGACTTGCAATCACAGAACATTTACCACCAT GGAAGAGAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCACAGCATTAGTGATGGACAACTTCAAGGTGGCCAGTCCAATAGTGAA CTATTTCAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCAAGGCTTTAATGTTTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAAT TCAGCACCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATCTAGCCTTTCTCAACAAACTCCCAGATTTAATCCCATTATGGTAACT TTAGCCCCAAATATCCAGACTGGTCGTAATACTCCTACATCTTTGCACATACATGGTGTACCTCCACCTGTACTTAACAGTCCACAGGGA AATTCTATCTATATTAGGCCTTACATTACAACTCCTGGTGGTACAACTCGACAGACACAACAGCATTCTGGCTGGGTATCTCAGTTTAAT CCCATGAACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCCCTGGACTACTTGTCCTGCATCTAATCCTCTGTCACATACCTCATCT CAACAGCCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACATGCCAATCAGTTCACCTACTACTTCACAACCACCAACCATTCATTCA TCTGGTAGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCAGAATATTTCAACAGGACCTCGAAAAAACCAGATTGAAATCAAACTT GAACCCCCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGGACCTCGAACCTCCAGCACTTCCTCTTCAGTCAATAGCCAGACCTTA AACAGAAATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAATACGGATGAGCTGATGTCCCGTAGTCAACCTAAGGTCTATATTTCA GCGAATGCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCCCACACTCTTCATATCCACAAACTCTGGAGCATCTGCTGCCTCCAGG AACATGTCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCACCATCCTCCCAAAAGTCGAGCAATAGGCAATAACTCTGCAACCTCT CCTCGAGTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAAAATTACAGTCTCTCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTG GTGTCCCCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGATCATTATGTAGAAACCGAGAATATTCAGCACCTCACGGACCCTACA TTAGCACATGTGGATAGAATAAGTGAAACACGGAAACTGAGTATGGGATCTGATGATGCTGCCTACACACAAGCTCTTTTGGTACACCAG AAGGCCAGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAAGAAAAAGCTGGATAAATTAAAATCTGAGGTTAATGAAATGGAAAAT AATCTAACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCAGATACCTTCCGAAGAAGAAATGCCAGAGGTAGAAATTGACATTGAT GATCTTCTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATTACAGGAAGCTCTTGTAGACTGCTACAAACCAACAGAGGAATTTATC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TAB2_ENST00000536230_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_3527nt AGTGAGGTGAACTCCTTCAGGGCCACAGGCTGTAAAGATCTAAACACCATCTGATCCAGTTTCAATATGACTGCCTGGATGAAGAAGGAT TTGAGACTAAGTTTATTCCTCCAAAGCAAACCAACTGAGAATGCAGAATAATAATAACCTGGATGCCTGCTGTGCTGTTCTCTCTCAGGA GAGTACAAGATATCTTTATGGTGAAGGAGACTTGAATTTTTCAGATGATTCTGGAATTTCTGGTCTACGCAATCACATGACTTCTCTCAA CTTGGACTTGCAATCACAGAACATTTACCACCATGGAAGAGAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCACAGCATTAGTGA TGGACAACTTCAAGGTGGCCAGTCCAATAGTGAACTATTTCAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCAAGGCTTTAATGT TTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAATTCAGCACCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATCTAGCCTTTCTCA ACAAACTCCCAGATTTAATCCCATTATGGTAACTTTAGCCCCAAATATCCAGACTGGTCGTAATACTCCTACATCTTTGCACATACATGG TGTACCTCCACCTGTACTTAACAGTCCACAGGGAAATTCTATCTATATTAGGCCTTACATTACAACTCCTGGTGGTACAACTCGACAGAC ACAACAGCATTCTGGCTGGGTATCTCAGTTTAATCCCATGAACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCCCTGGACTACTTG TCCTGCATCTAATCCTCTGTCACATACCTCATCTCAACAGCCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACATGCCAATCAGTTC ACCTACTACTTCACAACCACCAACCATTCATTCATCTGGTAGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCAGAATATTTCAAC AGGACCTCGAAAAAACCAGATTGAAATCAAACTTGAACCCCCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGGACCTCGAACCTC CAGCACTTCCTCTTCAGTCAATAGCCAGACCTTAAACAGAAATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAATACGGATGAGCT GATGTCCCGTAGTCAACCTAAGGTCTATATTTCAGCGAATGCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCCCACACTCTTCAT ATCCACAAACTCTGGAGCATCTGCTGCCTCCAGGAACATGTCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCACCATCCTCCCAA AAGTCGAGCAATAGGCAATAACTCTGCAACCTCTCCTCGAGTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAAAATTACAGTCTC TCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTGGTGTCCCCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGATCATTATGTAGA AACCGAGAATATTCAGCACCTCACGGACCCTACATTAGCACATGTGGATAGAATAAGTGAAACACGGAAACTGAGTATGGGATCTGATGA TGCTGCCTACACACAAGCTCTTTTGGTACACCAGAAGGCCAGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAAGAAAAAGCTGGA TAAATTAAAATCTGAGGTTAATGAAATGGAAAATAATCTAACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCAGATACCTTCCGA AGAAGAAATGCCAGAGGTAGAAATTGACATTGATGATCTTCTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATTACAGGAAGCTCT TGTAGACTGCTACAAACCAACAGAGGAATTTATCAAAGAGCTGCTTTCTCGGATAAGAGGCATGAGGAAACTGAGCCCTCCGCAGAAGAA GAGTGTATGATTCTGGAACAGGGTGAAACTCTCCCAGAGACGAAGAAAGAGTCCTGGGATTTGTACTTCATGAAGACTTTTGTGAAAGAA TAGGTGTCCTTATGAACAACGTTTTTGTTTTTTTTTTTTTCTTTTTTGGTGTGAAGGTGGGGGGGTCTATTAGACATTTATTCAAGAGCG TTCTTTTTTTGGTTTTAAAGGTTTTTGTTAATGTAATATTTTAATAGCAAAGATATCATGACTCTAGCCACAGCCTAACCAAGGATTATC AAAGGAGGTGGACACTCAAGGAAGGGCCACGCCAGGCTGCGTTTCCTGCAAGGACTCAGATGTTCAGTACCTTATGATACAGGGAAGATA GTTTTCTTACAAGTAGTTTGGTAATATTTTTTTTCTTAAGTTGTACATTTGACTCAGCTGTCAAATTTCTCACACTTGTATATATCTACA CACAACTAAGTTAAAATGTTGATGTGAGTTTTATTTCACATGGATGGAATAAACTTGTGGTTGTCCTTTAACTGGAGGTCCCAGCACATG TGTTTTCAAGAGGCCACTAGGCATTCTTCACTGAGTGCTGCTGACTTCAACGTTCACTTTATGCACCAAAGTGAAAGAATTCAGTGTATC CGTTATTTTAATGCACTACACCACAGAAATGTTAAGTTGGTCAAGGGCTTAATTTATGGAATTTCTATTATTTCATTGGTTGGGATGCTT TGCCAGGTCATGTGCTTATTGTCTCATTTTGTAGTCTTTTAAAGTTGTATGAACCCTTAATTTGAAGAACTAACTTGATTTCTAGAGAAA TATCCACACTATCTCAGTGGTATTTTGCATTGGAAAAAGGAAGCACTGTGTAGCAGTGAATTGTCTGCTTTCCACCGAGTACTGTGTTTA TTCTCTCTCCAGGAAAGCAGATCAAAAGAAAGTTAGCAGATCGAGTGTCTTCTTCCTTAGAAATAGGTTCTGGTAGCTTCTGTGCCTGGG TAGTATCAGACCAGTGGGAGTAAACCGAGTGTTAAGTGTCAAGGTGAGAAAGCCTCACATTCTCTCAAGACAGTTGCTCTAGGAGCTGAG TTGCTGGTTTGGAAGTGTGGAGATTGCATTTCTGGCTTCTCTCAATGGCTTGTGTTGAGGACTCTGGGTGCTCCTGGCCCTAATTGTGCA CCCTGATCCCCGTGCTTGGAGCTAGGCCTGGTGGCGTGCTCTAGCCCTCTCAGTTACCAGCTCTTTGGAGAAGGATCAAAATTCAGATGG AATGTGGGATGGGTAATAGGTGAGAGTAGAAACCCTTCCCTCCAGGAGGCCCCCGCTGACTCCCACAGAAACCCACCTACCATAAGATGT CTTCAGGTGGCCTTGTCCAAGGATGGGGGTCAGGCATTTTATATCAAGGGTGCTCTGAACATATTTTATTTTTTAAAAAAACTATGTTTG TGAATTTTGCGTATACTGGCAAGCTTTTGAAAATGTATTTAATTTTGTATTGTTTACCAATGATTTATTTACAAGATATTTACTCAAATA >In-frame_TAB2_ENST00000538427_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_3899nt ATCGAGCGCCTAGGAGAGCCCCGGGTGGGGGAGGGCGCAAGGGGCTCGGGAGGGCCCCTCCCTGCGTCGGCGCCCCTGACCCGCCCCCAG GCATGTGTGAGGTGGGGGCGGGGGAGGAAAAATCTCCTTTTGGCTCTAGTTTACTCTAGTTTCTCTTCTGCTTTCAAGGCTCCAGACCCA GTTCCTGGACCTGCCCTGGAAAAGAAGTATCCCGTAGAGATGAGCTCACTGCAGTTACTTAATTAACAATTTGTAAGCTGCAAAAATGGC AATGGGCCAACCAAGAACAGCTACAATTTGAATTTTTCTATTTCCAGAAAATGCTTGGACAGAAGAGATGAGTACTATTTCCACTAAGGC CTAGAATTGCCTACTGTACAAATAGTCCTGATCAGGCAATATACGAATGGCCCAAGGAAGCCACCAAATTGATTTTCAGGTTTTACATGA CCTGCGACAAAAATTCCCTGAAGTACCTGAAGTTGTTGTATCCAGGTGCATGTTACAGAATAATAATAACCTGGATGCCTGCTGTGCTGT TCTCTCTCAGGAGAGTACAAGATATCTTTATGGTGAAGGAGACTTGAATTTTTCAGATGATTCTGGAATTTCTGGTCTACGCAATCACAT GACTTCTCTCAACTTGGACTTGCAATCACAGAACATTTACCACCATGGAAGAGAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCA CAGCATTAGTGATGGACAACTTCAAGGTGGCCAGTCCAATAGTGAACTATTTCAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCA AGGCTTTAATGTTTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAATTCAGCACCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATC TAGCCTTTCTCAACAAACTCCCAGATTTAATCCCATTATGGTAACTTTAGCCCCAAATATCCAGACTGGTCGTAATACTCCTACATCTTT GCACATACATGGTGTACCTCCACCTGTACTTAACAGTCCACAGGGAAATTCTATCTATATTAGGCCTTACATTACAACTCCTGGTGGTAC AACTCGACAGACACAACAGCATTCTGGCTGGGTATCTCAGTTTAATCCCATGAACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCC CTGGACTACTTGTCCTGCATCTAATCCTCTGTCACATACCTCATCTCAACAGCCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACAT GCCAATCAGTTCACCTACTACTTCACAACCACCAACCATTCATTCATCTGGTAGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCA GAATATTTCAACAGGACCTCGAAAAAACCAGATTGAAATCAAACTTGAACCCCCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGG ACCTCGAACCTCCAGCACTTCCTCTTCAGTCAATAGCCAGACCTTAAACAGAAATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAA TACGGATGAGCTGATGTCCCGTAGTCAACCTAAGGTCTATATTTCAGCGAATGCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCC CACACTCTTCATATCCACAAACTCTGGAGCATCTGCTGCCTCCAGGAACATGTCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCA CCATCCTCCCAAAAGTCGAGCAATAGGCAATAACTCTGCAACCTCTCCTCGAGTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAA AATTACAGTCTCTCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTGGTGTCCCCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGA TCATTATGTAGAAACCGAGAATATTCAGCACCTCACGGACCCTACATTAGCACATGTGGATAGAATAAGTGAAACACGGAAACTGAGTAT GGGATCTGATGATGCTGCCTACACACAAGCTCTTTTGGTACACCAGAAGGCCAGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAA GAAAAAGCTGGATAAATTAAAATCTGAGGTTAATGAAATGGAAAATAATCTAACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCA GATACCTTCCGAAGAAGAAATGCCAGAGGTAGAAATTGACATTGATGATCTTCTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATT ACAGGAAGCTCTTGTAGACTGCTACAAACCAACAGAGGAATTTATCAAAGAGCTGCTTTCTCGGATAAGAGGCATGAGGAAACTGAGCCC TCCGCAGAAGAAGAGTGTATGATTCTGGAACAGGGTGAAACTCTCCCAGAGACGAAGAAAGAGTCCTGGGATTTGTACTTCATGAAGACT TTTGTGAAAGAATAGGTGTCCTTATGAACAACGTTTTTGTTTTTTTTTTTTTCTTTTTTGGTGTGAAGGTGGGGGGGTCTATTAGACATT TATTCAAGAGCGTTCTTTTTTTGGTTTTAAAGGTTTTTGTTAATGTAATATTTTAATAGCAAAGATATCATGACTCTAGCCACAGCCTAA CCAAGGATTATCAAAGGAGGTGGACACTCAAGGAAGGGCCACGCCAGGCTGCGTTTCCTGCAAGGACTCAGATGTTCAGTACCTTATGAT ACAGGGAAGATAGTTTTCTTACAAGTAGTTTGGTAATATTTTTTTTCTTAAGTTGTACATTTGACTCAGCTGTCAAATTTCTCACACTTG TATATATCTACACACAACTAAGTTAAAATGTTGATGTGAGTTTTATTTCACATGGATGGAATAAACTTGTGGTTGTCCTTTAACTGGAGG TCCCAGCACATGTGTTTTCAAGAGGCCACTAGGCATTCTTCACTGAGTGCTGCTGACTTCAACGTTCACTTTATGCACCAAAGTGAAAGA ATTCAGTGTATCCGTTATTTTAATGCACTACACCACAGAAATGTTAAGTTGGTCAAGGGCTTAATTTATGGAATTTCTATTATTTCATTG GTTGGGATGCTTTGCCAGGTCATGTGCTTATTGTCTCATTTTGTAGTCTTTTAAAGTTGTATGAACCCTTAATTTGAAGAACTAACTTGA TTTCTAGAGAAATATCCACACTATCTCAGTGGTATTTTGCATTGGAAAAAGGAAGCACTGTGTAGCAGTGAATTGTCTGCTTTCCACCGA GTACTGTGTTTATTCTCTCTCCAGGAAAGCAGATCAAAAGAAAGTTAGCAGATCGAGTGTCTTCTTCCTTAGAAATAGGTTCTGGTAGCT TCTGTGCCTGGGTAGTATCAGACCAGTGGGAGTAAACCGAGTGTTAAGTGTCAAGGTGAGAAAGCCTCACATTCTCTCAAGACAGTTGCT CTAGGAGCTGAGTTGCTGGTTTGGAAGTGTGGAGATTGCATTTCTGGCTTCTCTCAATGGCTTGTGTTGAGGACTCTGGGTGCTCCTGGC CCTAATTGTGCACCCTGATCCCCGTGCTTGGAGCTAGGCCTGGTGGCGTGCTCTAGCCCTCTCAGTTACCAGCTCTTTGGAGAAGGATCA AAATTCAGATGGAATGTGGGATGGGTAATAGGTGAGAGTAGAAACCCTTCCCTCCAGGAGGCCCCCGCTGACTCCCACAGAAACCCACCT ACCATAAGATGTCTTCAGGTGGCCTTGTCCAAGGATGGGGGTCAGGCATTTTATATCAAGGGTGCTCTGAACATATTTTATTTTTTAAAA AAACTATGTTTGTGAATTTTGCGTATACTGGCAAGCTTTTGAAAATGTATTTAATTTTGTATTGTTTACCAATGATTTATTTACAAGATA >In-frame_TAB2_ENST00000367456_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_4070nt GAAAAGTTTTAGGCAGCTAGGAATGTGGAGATGTGGGTAGTGGTGGCTGCCAAGCACAGGAAAATGATCATGCTGAACTGTACAAAGGAG ATTGTCTCTGAACCTTTTCATAGGTTCTGACACTCTATATATGTCATCTTATTTAAAACCCTCTGTATTAAAATGATAAGGATTTGGAGA CATTGAAATTATATAGAATTTAAATGTATGCATGTTCATATGTTTTTGCCTCTGGCTCATATTTCCAGAATACTTAACAGTATTTTAACA TTTTGTTTCTTATGATTCTGGTCCTAAAAAATCAAGGACGCTGCTTACTCAGAAAGCTAAAAAACCTGAGCTCCAGACCCAGTTCCTGGA CCTGCCCTGGAAAAGAAGTATCCCGTAGAGATGAGCTCACTGCAGTTACTTAATTAACAATTTGTAAGCTGCAAAAATGGCAATGGGCCA ACCAAGAACAGCTACAATTTGAATTTTTCTATTTCCAGAAAATGCTTGGACAGAAGAGATGAGTACTATTTCCACTAAGGCCTAGAATTG CCTACTGTACAAATAGTCCTGATCAGGCAATATACGAATGGCCCAAGGAAGCCACCAAATTGATTTTCAGGTTTTACATGACCTGCGACA AAAATTCCCTGAAGTACCTGAAGTTGTTGTATCCAGGTGCATGTTACAGAATAATAATAACCTGGATGCCTGCTGTGCTGTTCTCTCTCA GGAGAGTACAAGATATCTTTATGGTGAAGGAGACTTGAATTTTTCAGATGATTCTGGAATTTCTGGTCTACGCAATCACATGACTTCTCT CAACTTGGACTTGCAATCACAGAACATTTACCACCATGGAAGAGAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCACAGCATTAG TGATGGACAACTTCAAGGTGGCCAGTCCAATAGTGAACTATTTCAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCAAGGCTTTAA TGTTTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAATTCAGCACCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATCTAGCCTTTC TCAACAAACTCCCAGATTTAATCCCATTATGGTAACTTTAGCCCCAAATATCCAGACTGGTCGTAATACTCCTACATCTTTGCACATACA TGGTGTACCTCCACCTGTACTTAACAGTCCACAGGGAAATTCTATCTATATTAGGCCTTACATTACAACTCCTGGTGGTACAACTCGACA GACACAACAGCATTCTGGCTGGGTATCTCAGTTTAATCCCATGAACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCCCTGGACTAC TTGTCCTGCATCTAATCCTCTGTCACATACCTCATCTCAACAGCCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACATGCCAATCAG TTCACCTACTACTTCACAACCACCAACCATTCATTCATCTGGTAGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCAGAATATTTC AACAGGACCTCGAAAAAACCAGATTGAAATCAAACTTGAACCCCCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGGACCTCGAAC CTCCAGCACTTCCTCTTCAGTCAATAGCCAGACCTTAAACAGAAATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAATACGGATGA GCTGATGTCCCGTAGTCAACCTAAGGTCTATATTTCAGCGAATGCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCCCACACTCTT CATATCCACAAACTCTGGAGCATCTGCTGCCTCCAGGAACATGTCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCACCATCCTCC CAAAAGTCGAGCAATAGGCAATAACTCTGCAACCTCTCCTCGAGTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAAAATTACAGT CTCTCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTGGTGTCCCCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGATCATTATGT AGAAACCGAGAATATTCAGCACCTCACGGACCCTACATTAGCACATGTGGATAGAATAAGTGAAACACGGAAACTGAGTATGGGATCTGA TGATGCTGCCTACACACAAGCTCTTTTGGTACACCAGAAGGCCAGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAAGAAAAAGCT GGATAAATTAAAATCTGAGGTTAATGAAATGGAAAATAATCTAACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCAGATACCTTC CGAAGAAGAAATGCCAGAGGTAGAAATTGACATTGATGATCTTCTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATTACAGGAAGC TCTTGTAGACTGCTACAAACCAACAGAGGAATTTATCAAAGAGCTGCTTTCTCGGATAAGAGGCATGAGGAAACTGAGCCCTCCGCAGAA GAAGAGTGTATGATTCTGGAACAGGGTGAAACTCTCCCAGAGACGAAGAAAGAGTCCTGGGATTTGTACTTCATGAAGACTTTTGTGAAA GAATAGGTGTCCTTATGAACAACGTTTTTGTTTTTTTTTTTTTCTTTTTTGGTGTGAAGGTGGGGGGGTCTATTAGACATTTATTCAAGA GCGTTCTTTTTTTGGTTTTAAAGGTTTTTGTTAATGTAATATTTTAATAGCAAAGATATCATGACTCTAGCCACAGCCTAACCAAGGATT ATCAAAGGAGGTGGACACTCAAGGAAGGGCCACGCCAGGCTGCGTTTCCTGCAAGGACTCAGATGTTCAGTACCTTATGATACAGGGAAG ATAGTTTTCTTACAAGTAGTTTGGTAATATTTTTTTTCTTAAGTTGTACATTTGACTCAGCTGTCAAATTTCTCACACTTGTATATATCT ACACACAACTAAGTTAAAATGTTGATGTGAGTTTTATTTCACATGGATGGAATAAACTTGTGGTTGTCCTTTAACTGGAGGTCCCAGCAC ATGTGTTTTCAAGAGGCCACTAGGCATTCTTCACTGAGTGCTGCTGACTTCAACGTTCACTTTATGCACCAAAGTGAAAGAATTCAGTGT ATCCGTTATTTTAATGCACTACACCACAGAAATGTTAAGTTGGTCAAGGGCTTAATTTATGGAATTTCTATTATTTCATTGGTTGGGATG CTTTGCCAGGTCATGTGCTTATTGTCTCATTTTGTAGTCTTTTAAAGTTGTATGAACCCTTAATTTGAAGAACTAACTTGATTTCTAGAG AAATATCCACACTATCTCAGTGGTATTTTGCATTGGAAAAAGGAAGCACTGTGTAGCAGTGAATTGTCTGCTTTCCACCGAGTACTGTGT TTATTCTCTCTCCAGGAAAGCAGATCAAAAGAAAGTTAGCAGATCGAGTGTCTTCTTCCTTAGAAATAGGTTCTGGTAGCTTCTGTGCCT GGGTAGTATCAGACCAGTGGGAGTAAACCGAGTGTTAAGTGTCAAGGTGAGAAAGCCTCACATTCTCTCAAGACAGTTGCTCTAGGAGCT GAGTTGCTGGTTTGGAAGTGTGGAGATTGCATTTCTGGCTTCTCTCAATGGCTTGTGTTGAGGACTCTGGGTGCTCCTGGCCCTAATTGT GCACCCTGATCCCCGTGCTTGGAGCTAGGCCTGGTGGCGTGCTCTAGCCCTCTCAGTTACCAGCTCTTTGGAGAAGGATCAAAATTCAGA TGGAATGTGGGATGGGTAATAGGTGAGAGTAGAAACCCTTCCCTCCAGGAGGCCCCCGCTGACTCCCACAGAAACCCACCTACCATAAGA TGTCTTCAGGTGGCCTTGTCCAAGGATGGGGGTCAGGCATTTTATATCAAGGGTGCTCTGAACATATTTTATTTTTTAAAAAAACTATGT TTGTGAATTTTGCGTATACTGGCAAGCTTTTGAAAATGTATTTAATTTTGTATTGTTTACCAATGATTTATTTACAAGATATTTACTCAA >In-frame_TAB2_ENST00000286332_chr6_149718900_+_PPP1R14C_ENST00000361131_chr6_150535880_+_3583nt GAAAATGCTTGGACAGAAGAGATGAGTACTATTTCCACTAAGGCCTAGAATTGCCTACTGTACAAATAGTCCTGATCAGGCAATATACGA ATGGCCCAAGGAAGCCACCAAATTGATTTTCAGGTTTTACATGACCTGCGACAAAAATTCCCTGAAGTACCTGAAGTTGTTGTATCCAGG TGCATGTTACAGAATAATAATAACCTGGATGCCTGCTGTGCTGTTCTCTCTCAGGAGAGTACAAGATATCTTTATGGTGAAGGAGACTTG AATTTTTCAGATGATTCTGGAATTTCTGGTCTACGCAATCACATGACTTCTCTCAACTTGGACTTGCAATCACAGAACATTTACCACCAT GGAAGAGAAGGAAGTAGGATGAATGGAAGTAGGACTCTAACGCACAGCATTAGTGATGGACAACTTCAAGGTGGCCAGTCCAATAGTGAA CTATTTCAGCAGGAGCCACAGACAGCACCAGCTCAAGTTCCTCAAGGCTTTAATGTTTTTGGAATGTCCAGTTCCTCTGGTGCTTCAAAT TCAGCACCACATCTTGGATTTCACTTAGGCAGCAAAGGAACATCTAGCCTTTCTCAACAAACTCCCAGATTTAATCCCATTATGGTAACT TTAGCCCCAAATATCCAGACTGGTCGTAATACTCCTACATCTTTGCACATACATGGTGTACCTCCACCTGTACTTAACAGTCCACAGGGA AATTCTATCTATATTAGGCCTTACATTACAACTCCTGGTGGTACAACTCGACAGACACAACAGCATTCTGGCTGGGTATCTCAGTTTAAT CCCATGAACCCTCAGCAAGTTTATCAGCCTTCACAGCCTGGTCCCTGGACTACTTGTCCTGCATCTAATCCTCTGTCACATACCTCATCT CAACAGCCAAATCAGCAAGGCCACCAGACCTCTCATGTCTACATGCCAATCAGTTCACCTACTACTTCACAACCACCAACCATTCATTCA TCTGGTAGCTCACAGTCTTCTGCCCATAGCCAATATAACATTCAGAATATTTCAACAGGACCTCGAAAAAACCAGATTGAAATCAAACTT GAACCCCCACAAAGAAATAATTCTTCAAAACTGCGTTCTTCTGGACCTCGAACCTCCAGCACTTCCTCTTCAGTCAATAGCCAGACCTTA AACAGAAATCAGCCCACTGTTTACATAGCTGCCAGCCCCCCAAATACGGATGAGCTGATGTCCCGTAGTCAACCTAAGGTCTATATTTCA GCGAATGCTGCCACAGGAGATGAACAGGTCATGCGGAATCAGCCCACACTCTTCATATCCACAAACTCTGGAGCATCTGCTGCCTCCAGG AACATGTCTGGGCAAGTGAGCATGGGTCCTGCCTTTATTCATCACCATCCTCCCAAAAGTCGAGCAATAGGCAATAACTCTGCAACCTCT CCTCGAGTGGTAGTCACTCAGCCCAATACGAAATACACTTTCAAAATTACAGTCTCTCCCAATAAGCCCCCTGCAGTTTCACCAGGGGTG GTGTCCCCTACCTTTGAACTTACAAATCTTCTTAATCATCCTGATCATTATGTAGAAACCGAGAATATTCAGCACCTCACGGACCCTACA TTAGCACATGTGGATAGAATAAGTGAAACACGGAAACTGAGTATGGGATCTGATGATGCTGCCTACACACAAGCTCTTTTGGTACACCAG AAGGCCAGAATGGAACGACTTCAAAGAGAACTTGAGATTCAAAAGAAAAAGCTGGATAAATTAAAATCTGAGGTTAATGAAATGGAAAAT AATCTAACTCGAAGGCGCCTGAAAAGATCAAATTCTATATCCCAGATACCTTCCGAAGAAGAAATGCCAGAGGTAGAAATTGACATTGAT GATCTTCTTGATGCAGACAGTGATGAAGAGAGAGCTTCAAAATTACAGGAAGCTCTTGTAGACTGCTACAAACCAACAGAGGAATTTATC AAAGAGCTGCTTTCTCGGATAAGAGGCATGAGGAAACTGAGCCCTCCGCAGAAGAAGAGTGTATGATTCTGGAACAGGGTGAAACTCTCC CAGAGACGAAGAAAGAGTCCTGGGATTTGTACTTCATGAAGACTTTTGTGAAAGAATAGGTGTCCTTATGAACAACGTTTTTGTTTTTTT TTTTTTCTTTTTTGGTGTGAAGGTGGGGGGGTCTATTAGACATTTATTCAAGAGCGTTCTTTTTTTGGTTTTAAAGGTTTTTGTTAATGT AATATTTTAATAGCAAAGATATCATGACTCTAGCCACAGCCTAACCAAGGATTATCAAAGGAGGTGGACACTCAAGGAAGGGCCACGCCA GGCTGCGTTTCCTGCAAGGACTCAGATGTTCAGTACCTTATGATACAGGGAAGATAGTTTTCTTACAAGTAGTTTGGTAATATTTTTTTT CTTAAGTTGTACATTTGACTCAGCTGTCAAATTTCTCACACTTGTATATATCTACACACAACTAAGTTAAAATGTTGATGTGAGTTTTAT TTCACATGGATGGAATAAACTTGTGGTTGTCCTTTAACTGGAGGTCCCAGCACATGTGTTTTCAAGAGGCCACTAGGCATTCTTCACTGA GTGCTGCTGACTTCAACGTTCACTTTATGCACCAAAGTGAAAGAATTCAGTGTATCCGTTATTTTAATGCACTACACCACAGAAATGTTA AGTTGGTCAAGGGCTTAATTTATGGAATTTCTATTATTTCATTGGTTGGGATGCTTTGCCAGGTCATGTGCTTATTGTCTCATTTTGTAG TCTTTTAAAGTTGTATGAACCCTTAATTTGAAGAACTAACTTGATTTCTAGAGAAATATCCACACTATCTCAGTGGTATTTTGCATTGGA AAAAGGAAGCACTGTGTAGCAGTGAATTGTCTGCTTTCCACCGAGTACTGTGTTTATTCTCTCTCCAGGAAAGCAGATCAAAAGAAAGTT AGCAGATCGAGTGTCTTCTTCCTTAGAAATAGGTTCTGGTAGCTTCTGTGCCTGGGTAGTATCAGACCAGTGGGAGTAAACCGAGTGTTA AGTGTCAAGGTGAGAAAGCCTCACATTCTCTCAAGACAGTTGCTCTAGGAGCTGAGTTGCTGGTTTGGAAGTGTGGAGATTGCATTTCTG GCTTCTCTCAATGGCTTGTGTTGAGGACTCTGGGTGCTCCTGGCCCTAATTGTGCACCCTGATCCCCGTGCTTGGAGCTAGGCCTGGTGG CGTGCTCTAGCCCTCTCAGTTACCAGCTCTTTGGAGAAGGATCAAAATTCAGATGGAATGTGGGATGGGTAATAGGTGAGAGTAGAAACC CTTCCCTCCAGGAGGCCCCCGCTGACTCCCACAGAAACCCACCTACCATAAGATGTCTTCAGGTGGCCTTGTCCAAGGATGGGGGTCAGG CATTTTATATCAAGGGTGCTCTGAACATATTTTATTTTTTAAAAAAACTATGTTTGTGAATTTTGCGTATACTGGCAAGCTTTTGAAAAT |
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FusionGenePPI for TAB2_PPP1R14C |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TAB2 | CS, TAB1, MAP3K7, TAB3, TAB2, TRAF6, NCOR1, HDAC3, HDAC1, HDAC5, TBL1X, NFKB1, TNFRSF11A, XIAP, TRAF2, NUMBL, RIPK1, IRAK1, TNF, UBC, RIPK2, PPP6C, TRAF3IP1, TIRAP, CHUK, BNIP3P6, TLR3, ERBB4, BECN1, ESR1, RBCK1, TANK, PDLIM7, NR2C2, IKBKG, SMAD7, EDARADD, MAP3K8, NLK, TRIM5, ATG5, ATG13, TGFBR1, AR, TBL1XR1, MBD3, SIN3A, APP, WDR34, BST2, MALT1, HSP90AA1, IKBKB, NPM1, TRIM22, ZBTB16, CST9L, TGM2, VIM, FN1, GTF2I, PPP2CB, YWHAZ, FOSL1, SLC19A3, SIK1, SIK3, TRIM38, UBE2I, PIAS3, RFPL4B, CARD8, C9orf41, CNTROB, XPO1, DBN1, ARRB2, LITAF, MCM2, RNF4, F2R, MAPK14, USP18, CTDSP1, EMILIN1, SCRN1, CCDC102B, MANSC1, IL17RC, CYLD, TNIK | PPP1R14C | SAP25, VPS35, UBL7, ESR1, HMGCS1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | TAB2 | chr6:149718900 | chr6:150535880 | ENST00000286332 | + | 3 | 6 | 675_685 | 588 | 694 | polyubiquitin |
| Hgene | TAB2 | chr6:149718900 | chr6:150535880 | ENST00000367456 | + | 5 | 8 | 675_685 | 588 | 694 | polyubiquitin |
| Hgene | TAB2 | chr6:149718900 | chr6:150535880 | ENST00000392282 | + | 1 | 4 | 675_685 | -60 | 537 | polyubiquitin |
| Hgene | TAB2 | chr6:149718900 | chr6:150535880 | ENST00000538427 | + | 5 | 8 | 675_685 | 588 | 694 | polyubiquitin |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TAB2_PPP1R14C |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TAB2_PPP1R14C |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | TAB2 | C3554279 | CONGENITAL HEART DEFECTS, MULTIPLE TYPES, 2 | 1 | UNIPROT |
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