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Fusion gene ID: 36974 |
FusionGeneSummary for SYT14_HSD11B1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SYT14_HSD11B1 | Fusion gene ID: 36974 | Hgene | Tgene | Gene symbol | SYT14 | HSD11B1 | Gene ID | 255928 | 3290 |
| Gene name | synaptotagmin 14 | hydroxysteroid 11-beta dehydrogenase 1 | |
| Synonyms | SCAR11|sytXIV | 11-DH|11-beta-HSD1|CORTRD2|HDL|HSD11|HSD11B|HSD11L|SDR26C1 | |
| Cytomap | 1q32.2 | 1q32.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | synaptotagmin-14synaptotagmin XIV | corticosteroid 11-beta-dehydrogenase isozyme 1short chain dehydrogenase/reductase family 26C member 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8NB59 | P28845 | |
| Ensembl transtripts involved in fusion gene | ENST00000534859, ENST00000399639, ENST00000422431, ENST00000537238, ENST00000367019, ENST00000472886, ENST00000271745, ENST00000367015, | ENST00000367028, ENST00000261465, ENST00000367027, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 3 X 3 X 3=27 |
| # samples | 2 | 3 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SYT14 [Title/Abstract] AND HSD11B1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-BF-AAP1-01A | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000534859 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000534859 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000534859 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000399639 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000399639 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000399639 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| Frame-shift | ENST00000422431 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| Frame-shift | ENST00000422431 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| Frame-shift | ENST00000422431 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 5UTR-3CDS | ENST00000537238 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 5UTR-3CDS | ENST00000537238 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 5UTR-3CDS | ENST00000537238 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000367019 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000367019 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000367019 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000472886 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000472886 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| In-frame | ENST00000472886 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 3UTR-3CDS | ENST00000271745 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 3UTR-3CDS | ENST00000271745 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 3UTR-3CDS | ENST00000271745 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 5UTR-3CDS | ENST00000367015 | ENST00000367028 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 5UTR-3CDS | ENST00000367015 | ENST00000261465 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
| 5UTR-3CDS | ENST00000367015 | ENST00000367027 | SYT14 | chr1 | 210126101 | + | HSD11B1 | chr1 | 209905781 | + |
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FusionProtFeatures for SYT14_HSD11B1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SYT14 | HSD11B1 |
| Catalyzes reversibly the conversion of cortisol to theinactive metabolite cortisone. Catalyzes reversibly the conversionof 7-ketocholesterol to 7-beta-hydroxycholesterol. In intactcells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).{ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SYT14 | chr1:210126101 | chr1:209905781 | ENST00000422431 | + | 2 | 10 | 1_24 | 25 | 620 | Topological domain | Extracellular |
| Tgene | >HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 183_187 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | >HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 218_222 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | >HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 183_187 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | >HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 218_222 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | >HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 183_187 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | >HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 218_222 | 172 | 293 | Nucleotide binding | NADP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367015 | + | 1 | 8 | 276_378 | -86 | 518 | Domain | C2 1 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367015 | + | 1 | 8 | 417_521 | -86 | 518 | Domain | C2 2 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367019 | + | 2 | 9 | 276_378 | 20 | 575 | Domain | C2 1 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367019 | + | 2 | 9 | 417_521 | 20 | 575 | Domain | C2 2 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000422431 | + | 2 | 10 | 276_378 | 25 | 620 | Domain | C2 1 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000422431 | + | 2 | 10 | 417_521 | 25 | 620 | Domain | C2 2 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000472886 | + | 2 | 8 | 276_378 | 20 | 556 | Domain | C2 1 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000472886 | + | 2 | 8 | 417_521 | 20 | 556 | Domain | C2 2 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000534859 | + | 2 | 9 | 276_378 | 20 | 582 | Domain | C2 1 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000534859 | + | 2 | 9 | 417_521 | 20 | 582 | Domain | C2 2 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000537238 | + | 2 | 9 | 276_378 | -86 | 518 | Domain | C2 1 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000537238 | + | 2 | 9 | 417_521 | -86 | 518 | Domain | C2 2 |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367015 | + | 1 | 8 | 1_24 | -86 | 518 | Topological domain | Extracellular |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367015 | + | 1 | 8 | 48_555 | -86 | 518 | Topological domain | Cytoplasmic |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367019 | + | 2 | 9 | 1_24 | 20 | 575 | Topological domain | Extracellular |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367019 | + | 2 | 9 | 48_555 | 20 | 575 | Topological domain | Cytoplasmic |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000422431 | + | 2 | 10 | 48_555 | 25 | 620 | Topological domain | Cytoplasmic |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000472886 | + | 2 | 8 | 1_24 | 20 | 556 | Topological domain | Extracellular |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000472886 | + | 2 | 8 | 48_555 | 20 | 556 | Topological domain | Cytoplasmic |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000534859 | + | 2 | 9 | 1_24 | 20 | 582 | Topological domain | Extracellular |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000534859 | + | 2 | 9 | 48_555 | 20 | 582 | Topological domain | Cytoplasmic |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000537238 | + | 2 | 9 | 1_24 | -86 | 518 | Topological domain | Extracellular |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000537238 | + | 2 | 9 | 48_555 | -86 | 518 | Topological domain | Cytoplasmic |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367015 | + | 1 | 8 | 25_47 | -86 | 518 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000367019 | + | 2 | 9 | 25_47 | 20 | 575 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000422431 | + | 2 | 10 | 25_47 | 25 | 620 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000472886 | + | 2 | 8 | 25_47 | 20 | 556 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000534859 | + | 2 | 9 | 25_47 | 20 | 582 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | >SYT14 | chr1:210126101 | chr1:209905781 | ENST00000537238 | + | 2 | 9 | 25_47 | -86 | 518 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 119_121 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 41_67 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 92_93 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 119_121 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 41_67 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 92_93 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 119_121 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 41_67 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 92_93 | 172 | 293 | Nucleotide binding | NADP |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 1_7 | 172 | 293 | Topological domain | Cytoplasmic |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 25_292 | 172 | 293 | Topological domain | Lumenal |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 1_7 | 172 | 293 | Topological domain | Cytoplasmic |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 25_292 | 172 | 293 | Topological domain | Lumenal |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 1_7 | 172 | 293 | Topological domain | Cytoplasmic |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 25_292 | 172 | 293 | Topological domain | Lumenal |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000261465 | + | 4 | 7 | 8_24 | 172 | 293 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367027 | + | 3 | 6 | 8_24 | 172 | 293 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | HSD11B1 | chr1:210126101 | chr1:209905781 | ENST00000367028 | + | 4 | 7 | 8_24 | 172 | 293 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
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FusionGeneSequence for SYT14_HSD11B1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_141aa MAIEGGERTCGVHELICIRKGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_423nt ATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCC TATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTC TGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCC CTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_924nt AGCGCGTCCTCCGCCAGCCCTCGCGTCTGCTGCCCCCGCCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGA GAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTT GCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATA GACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGG GGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTT CTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTC TGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAAT GGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGT AAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAA AGGTCACATAAACTTTATAAATTCATAACTGGTAGCTATAACTTGAGCTTATTCAGGATGGTTTCTTTAAAACCATAAACTGTACAAATG >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_924nt AGCGCGTCCTCCGCCAGCCCTCGCGTCTGCTGCCCCCGCCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGA GAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTT GCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATA GACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGG GGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTT CTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTC TGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAAT GGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGT AAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAA AGGTCACATAAACTTTATAAATTCATAACTGGTAGCTATAACTTGAGCTTATTCAGGATGGTTTCTTTAAAACCATAAACTGTACAAATG >In-frame_SYT14_ENST00000534859_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_838nt AGCGCGTCCTCCGCCAGCCCTCGCGTCTGCTGCCCCCGCCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGA GAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTT GCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATA GACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGG GGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTT CTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTC TGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAAT GGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGT AAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAA >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_924nt AGCGCGTCCTCCGCCAGCCCTCGCGTCTGCTGCCCCCGCCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGA GAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTT GCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATA GACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGG GGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTT CTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTC TGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAAT GGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGT AAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAA AGGTCACATAAACTTTATAAATTCATAACTGGTAGCTATAACTTGAGCTTATTCAGGATGGTTTCTTTAAAACCATAAACTGTACAAATG >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_924nt AGCGCGTCCTCCGCCAGCCCTCGCGTCTGCTGCCCCCGCCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGA GAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTT GCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATA GACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGG GGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTT CTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTC TGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAAT GGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGT AAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAA AGGTCACATAAACTTTATAAATTCATAACTGGTAGCTATAACTTGAGCTTATTCAGGATGGTTTCTTTAAAACCATAAACTGTACAAATG >In-frame_SYT14_ENST00000399639_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_838nt AGCGCGTCCTCCGCCAGCCCTCGCGTCTGCTGCCCCCGCCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGA GAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTT GCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATA GACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGG GGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTT CTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTC TGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAAT GGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGT AAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAA >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_886nt CCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAG AAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATA TTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGT CCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTC ACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTTCTCTACTCAACGAGCTATAATATGGACAGATTCATAAA CAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTCTGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACAT CTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAATGGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTA ATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGTAAACATAGGTATAATTACCAGATAGTTATATTAAATTT ATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAAAGGTCACATAAACTTTATAAATTCATAACTGGTAGCTA >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_886nt CCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAG AAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATA TTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGT CCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTC ACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTTCTCTACTCAACGAGCTATAATATGGACAGATTCATAAA CAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTCTGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACAT CTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAATGGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTA ATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGTAAACATAGGTATAATTACCAGATAGTTATATTAAATTT ATATCTTATATATAATAATATGTGATGATTAATACAATATTAATTATAATAAAGGTCACATAAACTTTATAAATTCATAACTGGTAGCTA >In-frame_SYT14_ENST00000367019_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_800nt CCATCCAGTTGGTGCGGTCCATGGCGAGCGCATCATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAG AAAAGGGAAAGTGGCTTATCCAATGGTTGCTGCCTATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATA TTCAGTGTCCAGGGTCAATGTATCAATCACTCTCTGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGT CCATATGCAAGCAGCTCCAAAGGAGGAATGTGCCCTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTC ACTCTGGACCACTCTTCTGATCAGAAATCCATGCAGGAAGATCCTGGAATTTCTCTACTCAACGAGCTATAATATGGACAGATTCATAAA CAAGTAGGAACTCCCTGAGGGCTGGGCATGCTGAGGGATTTTGGGACTGTTCTGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACAT CTTCCCAGAGTGTCCCCAGAGACATGCAAGTCATGGGTCACACCTGACAAATGGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTA ATAATAATGAATGTCATGCACCGCTGCAGCCAGCAGTTGTAAAATTGTTAGTAAACATAGGTATAATTACCAGATAGTTATATTAAATTT >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000367028_chr1_209905781_+_866nt ATGGCGAGCGCATCATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATC CAATGGTTGCTGCCTATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATG TATCAATCACTCTCTGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAA AGGAGGAATGTGCCCTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGA TCAGAAATCCATGCAGGAAGATCCTGGAATTTCTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGG GCTGGGCATGCTGAGGGATTTTGGGACTGTTCTGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGA GACATGCAAGTCATGGGTCACACCTGACAAATGGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCA CCGCTGCAGCCAGCAGTTGTAAAATTGTTAGTAAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATA TGTGATGATTAATACAATATTAATTATAATAAAGGTCACATAAACTTTATAAATTCATAACTGGTAGCTATAACTTGAGCTTATTCAGGA >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000261465_chr1_209905781_+_866nt ATGGCGAGCGCATCATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATC CAATGGTTGCTGCCTATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATG TATCAATCACTCTCTGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAA AGGAGGAATGTGCCCTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGA TCAGAAATCCATGCAGGAAGATCCTGGAATTTCTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGG GCTGGGCATGCTGAGGGATTTTGGGACTGTTCTGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGA GACATGCAAGTCATGGGTCACACCTGACAAATGGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCA CCGCTGCAGCCAGCAGTTGTAAAATTGTTAGTAAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATA TGTGATGATTAATACAATATTAATTATAATAAAGGTCACATAAACTTTATAAATTCATAACTGGTAGCTATAACTTGAGCTTATTCAGGA >In-frame_SYT14_ENST00000472886_chr1_210126101_+_HSD11B1_ENST00000367027_chr1_209905781_+_780nt ATGGCGAGCGCATCATGGCGATTGAAGGTGGAGAGAGAACCTGTGGAGTACATGAACTTATCTGTATTAGAAAAGGGAAAGTGGCTTATC CAATGGTTGCTGCCTATTCTGCAAGCAAGTTTGCTTTGGATGGGTTCTTCTCCTCCATCAGAAAGGAATATTCAGTGTCCAGGGTCAATG TATCAATCACTCTCTGTGTTCTTGGCCTCATAGACACAGAAACAGCCATGAAGGCAGTTTCTGGGATAGTCCATATGCAAGCAGCTCCAA AGGAGGAATGTGCCCTGGAGATCATCAAAGGGGGAGCTCTGCGCCAAGAAGAAGTGTATTATGACAGCTCACTCTGGACCACTCTTCTGA TCAGAAATCCATGCAGGAAGATCCTGGAATTTCTCTACTCAACGAGCTATAATATGGACAGATTCATAAACAAGTAGGAACTCCCTGAGG GCTGGGCATGCTGAGGGATTTTGGGACTGTTCTGTCTCATGTTTATCTGAGCTCTTATCTATGAAGACATCTTCCCAGAGTGTCCCCAGA GACATGCAAGTCATGGGTCACACCTGACAAATGGAAGGAGTTCCTCTAACATTTGCAAAATGGAAATGTAATAATAATGAATGTCATGCA CCGCTGCAGCCAGCAGTTGTAAAATTGTTAGTAAACATAGGTATAATTACCAGATAGTTATATTAAATTTATATCTTATATATAATAATA |
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FusionGenePPI for SYT14_HSD11B1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SYT14 | SYT16 | HSD11B1 | CD36, GKAP1, DAD1, TMX2, UGT8, TMBIM6, GLB1L2, CDC42SE2, RAB18, NHLRC3, TOR1A, FAM69A, TMX4, MANEA, EGFR, NPTX1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SYT14_HSD11B1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | HSD11B1 | P28845 | DB00635 | Prednisone | Corticosteroid 11-beta-dehydrogenase isozyme 1 | small molecule | approved|vet_approved |
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RelatedDiseases for SYT14_HSD11B1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SYT14 | C3280226 | SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 11 | 1 | ORPHANET;UNIPROT |
| Tgene | HSD11B1 | C0020538 | Hypertensive disease | 3 | CTD_human |
| Tgene | HSD11B1 | C0028754 | Obesity | 2 | CTD_human |
| Tgene | HSD11B1 | C0003873 | Rheumatoid Arthritis | 1 | CTD_human |
| Tgene | HSD11B1 | C0011570 | Mental Depression | 1 | PSYGENET |
| Tgene | HSD11B1 | C0011581 | Depressive disorder | 1 | PSYGENET |
| Tgene | HSD11B1 | C0011853 | Diabetes Mellitus, Experimental | 1 | CTD_human |
| Tgene | HSD11B1 | C0020456 | Hyperglycemia | 1 | CTD_human |
| Tgene | HSD11B1 | C0021655 | Insulin Resistance | 1 | CTD_human |
| Tgene | HSD11B1 | C0162820 | Dermatitis, Allergic Contact | 1 | CTD_human |
| Tgene | HSD11B1 | C0311277 | Obesity, Abdominal | 1 | CTD_human |
| Tgene | HSD11B1 | C1291245 | Cortisone reductase deficiency | 1 | CTD_human |
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