	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 36958

FusionGeneSummary for SYNRG_SYNRG

Fusion gene summary

Fusion gene information	Fusion gene name: SYNRG_SYNRG
	Fusion gene ID: 36958
		Hgene	Tgene
	Gene symbol	SYNRG	SYNRG
	Gene ID	11276	11276
	Gene name	synergin gamma	synergin gamma
	Synonyms	AP1GBP1\|SYNG	AP1GBP1\|SYNG
	Cytomap	17q12	17q12
	Type of gene	protein-coding	protein-coding
	Description	synergin gammaAP1 gamma subunit binding protein 1AP1 subunit gamma-binding protein 1adaptor-related protein complex 1 gamma subunit-binding protein 1gamma-synergin	synergin gammaAP1 gamma subunit binding protein 1AP1 subunit gamma-binding protein 1adaptor-related protein complex 1 gamma subunit-binding protein 1gamma-synergin
	Modification date	20180519	20180519
	UniProtAcc	Q9UMZ2	Q9UMZ2
	Ensembl transtripts involved in fusion gene	ENST00000339208, ENST00000346661, ENST00000345615, ENST00000502449, ENST00000591288, ENST00000394378, ENST00000585472, ENST00000588194,	ENST00000339208, ENST00000346661, ENST00000345615, ENST00000502449, ENST00000591288, ENST00000394378, ENST00000585472, ENST00000588194,
Fusion gene scores	* DoF score	14 X 15 X 9=1890	4 X 7 X 3=84
	# samples	17	9
	** MAII score	log2(17/1890*10)=-3.47477958297073 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(9/84*10)=0.0995356735509144 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: SYNRG [Title/Abstract] AND SYNRG [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			AA233344	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
ChiTaRS3.1			BU685120	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
ChiTaRS3.1			AI863262	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
ChiTaRS3.1			AI668864	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
ChiTaRS3.1			BF727217	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-3UTR	ENST00000339208	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000339208	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000339208	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000339208	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000339208	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000339208	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000339208	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000339208	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000346661	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000346661	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000346661	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000346661	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000346661	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000346661	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000346661	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000346661	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000345615	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000345615	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000345615	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000345615	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000345615	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000345615	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000345615	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000345615	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000502449	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000502449	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000502449	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000502449	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000502449	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000502449	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000502449	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000502449	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000591288	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000591288	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000591288	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000591288	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000591288	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000591288	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000591288	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000591288	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000394378	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000394378	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000394378	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000394378	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000394378	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000394378	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000394378	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000394378	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000585472	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000585472	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000585472	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000585472	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000585472	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000585472	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000585472	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000585472	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000588194	ENST00000339208	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000588194	ENST00000346661	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000588194	ENST00000345615	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000588194	ENST00000502449	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000588194	ENST00000591288	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000588194	ENST00000394378	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000588194	ENST00000585472	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-intron	ENST00000588194	ENST00000588194	SYNRG	chr17	35877057	+	SYNRG	chr17	35875859	+
intron-3UTR	ENST00000339208	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000339208	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000339208	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000339208	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000339208	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000339208	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000339208	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000339208	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000346661	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000346661	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000346661	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000346661	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000346661	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000346661	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000346661	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000346661	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000345615	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000345615	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000345615	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000345615	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000345615	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000345615	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000345615	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000345615	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000502449	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000502449	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000502449	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000502449	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000502449	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000502449	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000502449	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000502449	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000591288	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000591288	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000591288	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000591288	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000591288	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000591288	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000591288	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000591288	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000394378	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000394378	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000394378	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000394378	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000394378	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000394378	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000394378	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000394378	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000585472	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000585472	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000585472	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000585472	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000585472	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000585472	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000585472	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000585472	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000588194	ENST00000339208	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000588194	ENST00000346661	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000588194	ENST00000345615	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000588194	ENST00000502449	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000588194	ENST00000591288	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000588194	ENST00000394378	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000588194	ENST00000585472	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-intron	ENST00000588194	ENST00000588194	SYNRG	chr17	35877061	+	SYNRG	chr17	35875858	+
intron-3UTR	ENST00000339208	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000339208	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000339208	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000339208	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000339208	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000339208	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000339208	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000339208	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000346661	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000346661	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000346661	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000346661	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000346661	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000346661	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000346661	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000346661	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000345615	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000345615	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000345615	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000345615	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000345615	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000345615	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000345615	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000345615	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000502449	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000502449	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000502449	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000502449	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000502449	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000502449	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000502449	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000502449	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000591288	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000591288	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000591288	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000591288	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000591288	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000591288	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000591288	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000591288	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000394378	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000394378	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000394378	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000394378	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000394378	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000394378	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000394378	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000394378	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000585472	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000585472	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000585472	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000585472	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000585472	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000585472	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000585472	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000585472	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000588194	ENST00000339208	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000588194	ENST00000346661	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000588194	ENST00000345615	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000588194	ENST00000502449	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000588194	ENST00000591288	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000588194	ENST00000394378	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000588194	ENST00000585472	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-intron	ENST00000588194	ENST00000588194	SYNRG	chr17	35877063	+	SYNRG	chr17	35875852	+
intron-3UTR	ENST00000339208	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000339208	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000339208	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000339208	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000339208	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000339208	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000339208	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000339208	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000346661	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000346661	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000346661	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000346661	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000346661	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000346661	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000346661	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000346661	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000345615	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000345615	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000345615	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000345615	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000345615	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000345615	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000345615	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000345615	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000502449	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000502449	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000502449	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000502449	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000502449	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000502449	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000502449	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000502449	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000591288	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000591288	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000591288	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000591288	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000591288	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000591288	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000591288	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000591288	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000394378	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000394378	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000394378	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000394378	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000394378	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000394378	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000394378	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000394378	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000585472	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000585472	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000585472	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000585472	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000585472	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000585472	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000585472	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000585472	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000588194	ENST00000339208	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-3UTR	ENST00000588194	ENST00000346661	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000588194	ENST00000345615	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000588194	ENST00000502449	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000588194	ENST00000591288	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000588194	ENST00000394378	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000588194	ENST00000585472	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-
intron-intron	ENST00000588194	ENST00000588194	SYNRG	chr17	35875858	-	SYNRG	chr17	35877061	-

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FusionProtFeatures for SYNRG_SYNRG

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
SYNRG Q9UMZ2	SYNRG Q9UMZ2
May play a role in endocytosis and/or membranetrafficking at the trans-Golgi network (TGN). May act by linkingthe adapter protein complex AP-1 to other proteins.	May play a role in endocytosis and/or membranetrafficking at the trans-Golgi network (TGN). May act by linkingthe adapter protein complex AP-1 to other proteins.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for SYNRG_SYNRG

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for SYNRG_SYNRG

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for SYNRG_SYNRG

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SYNRG_SYNRG

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Hgene	SYNRG	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
Tgene	SYNRG	C0023893	Liver Cirrhosis, Experimental	1	CTD_human

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Fusion gene ID: 36958

FusionGeneSummary for SYNRG_SYNRG

FusionProtFeatures for SYNRG_SYNRG

FusionGeneSequence for SYNRG_SYNRG

FusionGenePPI for SYNRG_SYNRG

RelatedDrugs for SYNRG_SYNRG

RelatedDiseases for SYNRG_SYNRG