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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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Fusion gene ID: 36812

FusionGeneSummary for SUSD4_NVL

check button Fusion gene summary
Fusion gene informationFusion gene name: SUSD4_NVL
Fusion gene ID: 36812
HgeneTgene
Gene symbol

SUSD4

NVL

Gene ID

55061

4931

Gene namesushi domain containing 4nuclear VCP-like
SynonymsPRO222NVL2
Cytomap

1q41

1q42.11

Type of geneprotein-codingprotein-coding
Descriptionsushi domain-containing protein 4YHGM196testicular secretory protein Li 55nuclear valosin-containing protein-likeNVLp
Modification date2018051920180523
UniProtAcc

Q5VX71

O15381

Ensembl transtripts involved in fusion geneENST00000343846, ENST00000366878, 
ENST00000484758, ENST00000494793, 
ENST00000478605, ENST00000454695, 
ENST00000344029, ENST00000366877, 
ENST00000391875, ENST00000281701, 
ENST00000469075, ENST00000482491, 
ENST00000340871, ENST00000361463, 
ENST00000468673, 
Fusion gene scores* DoF score4 X 2 X 3=243 X 3 X 3=27
# samples 43
** MAII scorelog2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SUSD4 [Title/Abstract] AND NVL [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSUSD4

GO:0030449

regulation of complement activation

23482636


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBRCATCGA-AO-A12D-01ASUSD4chr1

223536620

-NVLchr1

224468887

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000343846ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
In-frameENST00000343846ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
In-frameENST00000343846ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
In-frameENST00000343846ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
In-frameENST00000343846ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
In-frameENST00000343846ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5CDS-intronENST00000343846ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366878ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366878ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366878ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366878ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366878ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366878ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5CDS-intronENST00000366878ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000484758ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000484758ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000484758ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000484758ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000484758ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000484758ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5CDS-intronENST00000484758ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000494793ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000494793ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000494793ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000494793ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000494793ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000494793ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5CDS-intronENST00000494793ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000478605ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000478605ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000478605ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000478605ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000478605ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000478605ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-intronENST00000478605ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000454695ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000454695ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000454695ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000454695ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000454695ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-3CDSENST00000454695ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5UTR-intronENST00000454695ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000344029ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000344029ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000344029ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000344029ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000344029ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000344029ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5CDS-intronENST00000344029ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366877ENST00000391875SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366877ENST00000281701SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366877ENST00000469075SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366877ENST00000482491SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366877ENST00000340871SUSD4chr1

223536620

-NVLchr1

224468887

-
Frame-shiftENST00000366877ENST00000361463SUSD4chr1

223536620

-NVLchr1

224468887

-
5CDS-intronENST00000366877ENST00000468673SUSD4chr1

223536620

-NVLchr1

224468887

-

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FusionProtFeatures for SUSD4_NVL


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SUSD4

Q5VX71

NVL

O15381

Acts as complement inhibitor by disrupting the formationof the classical C3 convertase. Isoform 3 inhibits the classicalcomplement pathway, while membrane-bound isoform 1 inhibitsdeposition of C3b via both the classical and alternativecomplement pathways. {ECO:0000269|PubMed:23482636}. Participates in the assembly of the telomeraseholoenzyme and effecting of telomerase activity via itsinteraction with TERT (PubMed:22226966). May play a role in 60Sribosomal subunit biogenesis (PubMed:15469983, PubMed:16782053).{ECO:0000269|PubMed:15469983, ECO:0000269|PubMed:16782053,ECO:0000269|PubMed:22226966}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNVLchr1:223536620chr1:224468887ENST00000340871-1221622_629444668Nucleotide bindingATP
TgeneNVLchr1:223536620chr1:224468887ENST00000391875-1322622_629527751Nucleotide bindingATP
TgeneNVLchr1:223536620chr1:224468887ENST00000469075-1322622_629542766Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSUSD4chr1:223536620chr1:224468887ENST00000343846-18120_17949491DomainSushi 2
HgeneSUSD4chr1:223536620chr1:224468887ENST00000343846-18178_23949491DomainSushi 3
HgeneSUSD4chr1:223536620chr1:224468887ENST00000343846-18241_30449491DomainSushi 4
HgeneSUSD4chr1:223536620chr1:224468887ENST00000343846-1855_11949491DomainSushi 1
HgeneSUSD4chr1:223536620chr1:224468887ENST00000344029-26120_17949291DomainSushi 2
HgeneSUSD4chr1:223536620chr1:224468887ENST00000344029-26178_23949291DomainSushi 3
HgeneSUSD4chr1:223536620chr1:224468887ENST00000344029-26241_30449291DomainSushi 4
HgeneSUSD4chr1:223536620chr1:224468887ENST00000344029-2655_11949291DomainSushi 1
HgeneSUSD4chr1:223536620chr1:224468887ENST00000366878-29120_17949491DomainSushi 2
HgeneSUSD4chr1:223536620chr1:224468887ENST00000366878-29178_23949491DomainSushi 3
HgeneSUSD4chr1:223536620chr1:224468887ENST00000366878-29241_30449491DomainSushi 4
HgeneSUSD4chr1:223536620chr1:224468887ENST00000366878-2955_11949491DomainSushi 1
HgeneSUSD4chr1:223536620chr1:224468887ENST00000343846-18341_49049491Topological domainCytoplasmic
HgeneSUSD4chr1:223536620chr1:224468887ENST00000343846-1842_31949491Topological domainExtracellular
HgeneSUSD4chr1:223536620chr1:224468887ENST00000344029-26341_49049291Topological domainCytoplasmic
HgeneSUSD4chr1:223536620chr1:224468887ENST00000344029-2642_31949291Topological domainExtracellular
HgeneSUSD4chr1:223536620chr1:224468887ENST00000366878-29341_49049491Topological domainCytoplasmic
HgeneSUSD4chr1:223536620chr1:224468887ENST00000366878-2942_31949491Topological domainExtracellular
HgeneSUSD4chr1:223536620chr1:224468887ENST00000343846-18320_34049491TransmembraneHelical
HgeneSUSD4chr1:223536620chr1:224468887ENST00000344029-26320_34049291TransmembraneHelical
HgeneSUSD4chr1:223536620chr1:224468887ENST00000366878-29320_34049491TransmembraneHelical
TgeneNVLchr1:223536620chr1:224468887ENST00000281701-1423218_232633857MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000281701-142349_52633857MotifNucleolar localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000281701-142385_88633857MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000340871-1221218_232444668MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000340871-122149_52444668MotifNucleolar localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000340871-122185_88444668MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000391875-1322218_232527751MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000391875-132249_52527751MotifNucleolar localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000391875-132285_88527751MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000469075-1322218_232542766MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000469075-132249_52542766MotifNucleolar localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000469075-132285_88542766MotifNuclear localization signal
TgeneNVLchr1:223536620chr1:224468887ENST00000281701-1423305_312633857Nucleotide bindingATP
TgeneNVLchr1:223536620chr1:224468887ENST00000281701-1423622_629633857Nucleotide bindingATP
TgeneNVLchr1:223536620chr1:224468887ENST00000340871-1221305_312444668Nucleotide bindingATP
TgeneNVLchr1:223536620chr1:224468887ENST00000391875-1322305_312527751Nucleotide bindingATP
TgeneNVLchr1:223536620chr1:224468887ENST00000469075-1322305_312542766Nucleotide bindingATP


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FusionGeneSequence for SUSD4_NVL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000391875_chr1_224468887_-_273aa
MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGCCKXVRTKFYICQGPRITKHVCWXEXTCCATSFSTSQELS
TLCDILXXSGCFMSSKIRPRDRGKCPSGESATYRDGWSGSTPAGFYYGSHXQARYNXPCNPAPGPPGQNTVCGFTAPCRSPCHLKNYHKK
WYQTTTGCRCKFGSNCWXPSLXLLYGRRSLCFGTRSFYLCPETGNGKTEEWKXKRXTQGXSXAFXRSFQESKIIYIKKGSNHVXTFAGVP

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000281701_chr1_224468887_-_273aa
MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGCCKXVRTKFYICQGPRITKHVCWXEXTCCATSFSTSQELS
TLCDILXXSGCFMSSKIRPRDRGKCPSGESATYRDGWSGSTPAGFYYGSHXQARYNXPCNPAPGPPGQNTVCGFTAPCRSPCHLKNYHKK
WYQTTTGCRCKFGSNCWXPSLXLLYGRRSLCFGTRSFYLCPETGNGKTEEWKXKRXTQGXSXAFXRSFQESKIIYIKKGSNHVXTFAGVP

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000469075_chr1_224468887_-_273aa
MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGCCKXVRTKFYICQGPRITKHVCWXEXTCCATSFSTSQELS
TLCDILXXSGCFMSSKIRPRDRGKCPSGESATYRDGWSGSTPAGFYYGSHXQARYNXPCNPAPGPPGQNTVCGFTAPCRSPCHLKNYHKK
WYQTTTGCRCKFGSNCWXPSLXLLYGRRSLCFGTRSFYLCPETGNGKTEEWKXKRXTQGXSXAFXRSFQESKIIYIKKGSNHVXTFAGVP

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000482491_chr1_224468887_-_273aa
MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGCCKXVRTKFYICQGPRITKHVCWXEXTCCATSFSTSQELS
TLCDILXXSGCFMSSKIRPRDRGKCPSGESATYRDGWSGSTPAGFYYGSHXQARYNXPCNPAPGPPGQNTVCGFTAPCRSPCHLKNYHKK
WYQTTTGCRCKFGSNCWXPSLXLLYGRRSLCFGTRSFYLCPETGNGKTEEWKXKRXTQGXSXAFXRSFQESKIIYIKKGSNHVXTFAGVP

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000340871_chr1_224468887_-_273aa
MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGCCKXVRTKFYICQGPRITKHVCWXEXTCCATSFSTSQELS
TLCDILXXSGCFMSSKIRPRDRGKCPSGESATYRDGWSGSTPAGFYYGSHXQARYNXPCNPAPGPPGQNTVCGFTAPCRSPCHLKNYHKK
WYQTTTGCRCKFGSNCWXPSLXLLYGRRSLCFGTRSFYLCPETGNGKTEEWKXKRXTQGXSXAFXRSFQESKIIYIKKGSNHVXTFAGVP

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000361463_chr1_224468887_-_112aa
MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGCCKXVRTKFYICQGPRITKHVCWXEXTCCATSFSTSQELS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000391875_chr1_224468887_-_820nt
ATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACTCTTG
GCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATTTTAT
ATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACTCAGC
ACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGAATCA
GCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTGCAAT
CCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAAAAAA
TGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATCTCTC
TGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGGTTAG
TCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGTCCCT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000281701_chr1_224468887_-_820nt
ATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACTCTTG
GCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATTTTAT
ATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACTCAGC
ACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGAATCA
GCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTGCAAT
CCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAAAAAA
TGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATCTCTC
TGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGGTTAG
TCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGTCCCT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000469075_chr1_224468887_-_820nt
ATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACTCTTG
GCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATTTTAT
ATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACTCAGC
ACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGAATCA
GCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTGCAAT
CCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAAAAAA
TGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATCTCTC
TGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGGTTAG
TCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGTCCCT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000482491_chr1_224468887_-_820nt
ATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACTCTTG
GCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATTTTAT
ATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACTCAGC
ACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGAATCA
GCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTGCAAT
CCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAAAAAA
TGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATCTCTC
TGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGGTTAG
TCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGTCCCT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000340871_chr1_224468887_-_820nt
ATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACTCTTG
GCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATTTTAT
ATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACTCAGC
ACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGAATCA
GCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTGCAAT
CCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAAAAAA
TGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATCTCTC
TGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGGTTAG
TCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGTCCCT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000361463_chr1_224468887_-_337nt
ATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACTCTTG
GCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATTTTAT
ATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACTCAGC


* Fusion transcript sequences (Full-length transcript).
>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000391875_chr1_224468887_-_1746nt
CAGGTAAGACCGACAGTCCCGGAAGGGTCTTCCATTCCGAGGAGGCGCGCGCAGGCCGGGGAGGGGGAGTTGGTGCCTGGTGCAGCTCCC
CAAGGGAGAATTTTTTTTTTTTTTTTGACAGCGCAGAGAAATCTCACTGGGGACTGGGGCAGTAGGATCGATCCCAATCCCGAGGAAAAC
CAGAGAAGTAGCTGGGGGAGACGGTGCCACATTGTGAGATTCCCAGAGTGAAATGTATAGGCCCAGGGAAAAGTGTCTTCGCGGCCCCGA
GACGCGGGGAGGCTCTAGACTTTCCTGTGGTGGGCACAGCTGCTGAATCCCGGGGACCGGCGCGGAGCCAATGTGCGCTAACCCCTGCCC
TCCCTCCTGTCCTCCATCCCCCAGCACGCGCAGCATCCCACGGCGGCTGTTACTCAGTGCACCCGGCTCGGGGGAAGGCGGGGGACCTCG
CCGTGGGAAAGGGGGCGGGGGCCGCGCGGGGGAGGAACCAGGATGGAGCCTGGGAAGCCGAGGCGCCGGGTCCCAGAGCGGAGGAGGGGG
AGCGTGGCCCCCGAGCCCGGACAGACTGGCTTATTGTGGTGTTCCGCTTCTGGTTGCAGACTCTTGCAAGCTGGATGCCCTCTGTGGATG
AAAGATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACT
CTTGGCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATT
TTATATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACT
CAGCACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGA
ATCAGCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTG
CAATCCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAA
AAAATGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATC
TCTCTGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGG
TTAGTCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGT
CCCTCAGCCGGTGATGTCTCCAGCAGCCGGCTTAGAGGAGCTAGCCCATCAAGCCGGCAGAGAATCCCCCACACGCTCTGAAGGACCCAC
TTTCAGCTGGACACAGGCGCGGCCTCATGTAAACATTTTATTTTCAAATGAATGAGGCCAAGCTGAAGCTGAAGCTGAAGATTCTTCCCA
TCTGGCCAGCCTTGTGTGAAAATGCCTTCTTCCTCTTTAAGAAAAAGGACAATTTTTAAACTGCTGAAATAAAATGACTGTTACATTTTT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000281701_chr1_224468887_-_1746nt
CAGGTAAGACCGACAGTCCCGGAAGGGTCTTCCATTCCGAGGAGGCGCGCGCAGGCCGGGGAGGGGGAGTTGGTGCCTGGTGCAGCTCCC
CAAGGGAGAATTTTTTTTTTTTTTTTGACAGCGCAGAGAAATCTCACTGGGGACTGGGGCAGTAGGATCGATCCCAATCCCGAGGAAAAC
CAGAGAAGTAGCTGGGGGAGACGGTGCCACATTGTGAGATTCCCAGAGTGAAATGTATAGGCCCAGGGAAAAGTGTCTTCGCGGCCCCGA
GACGCGGGGAGGCTCTAGACTTTCCTGTGGTGGGCACAGCTGCTGAATCCCGGGGACCGGCGCGGAGCCAATGTGCGCTAACCCCTGCCC
TCCCTCCTGTCCTCCATCCCCCAGCACGCGCAGCATCCCACGGCGGCTGTTACTCAGTGCACCCGGCTCGGGGGAAGGCGGGGGACCTCG
CCGTGGGAAAGGGGGCGGGGGCCGCGCGGGGGAGGAACCAGGATGGAGCCTGGGAAGCCGAGGCGCCGGGTCCCAGAGCGGAGGAGGGGG
AGCGTGGCCCCCGAGCCCGGACAGACTGGCTTATTGTGGTGTTCCGCTTCTGGTTGCAGACTCTTGCAAGCTGGATGCCCTCTGTGGATG
AAAGATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACT
CTTGGCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATT
TTATATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACT
CAGCACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGA
ATCAGCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTG
CAATCCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAA
AAAATGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATC
TCTCTGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGG
TTAGTCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGT
CCCTCAGCCGGTGATGTCTCCAGCAGCCGGCTTAGAGGAGCTAGCCCATCAAGCCGGCAGAGAATCCCCCACACGCTCTGAAGGACCCAC
TTTCAGCTGGACACAGGCGCGGCCTCATGTAAACATTTTATTTTCAAATGAATGAGGCCAAGCTGAAGCTGAAGCTGAAGATTCTTCCCA
TCTGGCCAGCCTTGTGTGAAAATGCCTTCTTCCTCTTTAAGAAAAAGGACAATTTTTAAACTGCTGAAATAAAATGACTGTTACATTTTT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000469075_chr1_224468887_-_1711nt
CAGGTAAGACCGACAGTCCCGGAAGGGTCTTCCATTCCGAGGAGGCGCGCGCAGGCCGGGGAGGGGGAGTTGGTGCCTGGTGCAGCTCCC
CAAGGGAGAATTTTTTTTTTTTTTTTGACAGCGCAGAGAAATCTCACTGGGGACTGGGGCAGTAGGATCGATCCCAATCCCGAGGAAAAC
CAGAGAAGTAGCTGGGGGAGACGGTGCCACATTGTGAGATTCCCAGAGTGAAATGTATAGGCCCAGGGAAAAGTGTCTTCGCGGCCCCGA
GACGCGGGGAGGCTCTAGACTTTCCTGTGGTGGGCACAGCTGCTGAATCCCGGGGACCGGCGCGGAGCCAATGTGCGCTAACCCCTGCCC
TCCCTCCTGTCCTCCATCCCCCAGCACGCGCAGCATCCCACGGCGGCTGTTACTCAGTGCACCCGGCTCGGGGGAAGGCGGGGGACCTCG
CCGTGGGAAAGGGGGCGGGGGCCGCGCGGGGGAGGAACCAGGATGGAGCCTGGGAAGCCGAGGCGCCGGGTCCCAGAGCGGAGGAGGGGG
AGCGTGGCCCCCGAGCCCGGACAGACTGGCTTATTGTGGTGTTCCGCTTCTGGTTGCAGACTCTTGCAAGCTGGATGCCCTCTGTGGATG
AAAGATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACT
CTTGGCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATT
TTATATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACT
CAGCACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGA
ATCAGCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTG
CAATCCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAA
AAAATGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATC
TCTCTGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGG
TTAGTCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGT
CCCTCAGCCGGTGATGTCTCCAGCAGCCGGCTTAGAGGAGCTAGCCCATCAAGCCGGCAGAGAATCCCCCACACGCTCTGAAGGACCCAC
TTTCAGCTGGACACAGGCGCGGCCTCATGTAAACATTTTATTTTCAAATGAATGAGGCCAAGCTGAAGCTGAAGCTGAAGATTCTTCCCA
TCTGGCCAGCCTTGTGTGAAAATGCCTTCTTCCTCTTTAAGAAAAAGGACAATTTTTAAACTGCTGAAATAAAATGACTGTTACATTTTT

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000482491_chr1_224468887_-_1626nt
CAGGTAAGACCGACAGTCCCGGAAGGGTCTTCCATTCCGAGGAGGCGCGCGCAGGCCGGGGAGGGGGAGTTGGTGCCTGGTGCAGCTCCC
CAAGGGAGAATTTTTTTTTTTTTTTTGACAGCGCAGAGAAATCTCACTGGGGACTGGGGCAGTAGGATCGATCCCAATCCCGAGGAAAAC
CAGAGAAGTAGCTGGGGGAGACGGTGCCACATTGTGAGATTCCCAGAGTGAAATGTATAGGCCCAGGGAAAAGTGTCTTCGCGGCCCCGA
GACGCGGGGAGGCTCTAGACTTTCCTGTGGTGGGCACAGCTGCTGAATCCCGGGGACCGGCGCGGAGCCAATGTGCGCTAACCCCTGCCC
TCCCTCCTGTCCTCCATCCCCCAGCACGCGCAGCATCCCACGGCGGCTGTTACTCAGTGCACCCGGCTCGGGGGAAGGCGGGGGACCTCG
CCGTGGGAAAGGGGGCGGGGGCCGCGCGGGGGAGGAACCAGGATGGAGCCTGGGAAGCCGAGGCGCCGGGTCCCAGAGCGGAGGAGGGGG
AGCGTGGCCCCCGAGCCCGGACAGACTGGCTTATTGTGGTGTTCCGCTTCTGGTTGCAGACTCTTGCAAGCTGGATGCCCTCTGTGGATG
AAAGATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACT
CTTGGCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATT
TTATATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACT
CAGCACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGA
ATCAGCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTG
CAATCCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAA
AAAATGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATC
TCTCTGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGG
TTAGTCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGT
CCCTCAGCCGGTGATGTCTCCAGCAGCCGGCTTAGAGGAGCTAGCCCATCAAGCCGGCAGAGAATCCCCCACACGCTCTGAAGGACCCAC
TTTCAGCTGGACACAGGCGCGGCCTCATGTAAACATTTTATTTTCAAATGAATGAGGCCAAGCTGAAGCTGAAGCTGAAGATTCTTCCCA

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000340871_chr1_224468887_-_1626nt
CAGGTAAGACCGACAGTCCCGGAAGGGTCTTCCATTCCGAGGAGGCGCGCGCAGGCCGGGGAGGGGGAGTTGGTGCCTGGTGCAGCTCCC
CAAGGGAGAATTTTTTTTTTTTTTTTGACAGCGCAGAGAAATCTCACTGGGGACTGGGGCAGTAGGATCGATCCCAATCCCGAGGAAAAC
CAGAGAAGTAGCTGGGGGAGACGGTGCCACATTGTGAGATTCCCAGAGTGAAATGTATAGGCCCAGGGAAAAGTGTCTTCGCGGCCCCGA
GACGCGGGGAGGCTCTAGACTTTCCTGTGGTGGGCACAGCTGCTGAATCCCGGGGACCGGCGCGGAGCCAATGTGCGCTAACCCCTGCCC
TCCCTCCTGTCCTCCATCCCCCAGCACGCGCAGCATCCCACGGCGGCTGTTACTCAGTGCACCCGGCTCGGGGGAAGGCGGGGGACCTCG
CCGTGGGAAAGGGGGCGGGGGCCGCGCGGGGGAGGAACCAGGATGGAGCCTGGGAAGCCGAGGCGCCGGGTCCCAGAGCGGAGGAGGGGG
AGCGTGGCCCCCGAGCCCGGACAGACTGGCTTATTGTGGTGTTCCGCTTCTGGTTGCAGACTCTTGCAAGCTGGATGCCCTCTGTGGATG
AAAGATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACT
CTTGGCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATT
TTATATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACT
CAGCACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGACAGGGGCAAGTGTCCGAGTGGTGA
ATCAGCTACTTACAGAGATGGATGGTCTGGAAGCACGCCAGCAGGTTTTTATTATGGCAGCCACTAACAGGCCAGATATAATTGACCCTG
CAATCCTGCGCCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAA
AAAATGGTACCAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATC
TCTCTGCTTTGGTACGAGAAGCTTCTATCTGTGCCCTGAGACAGGAAATGGCAAGACAGAAGAGTGGAAATGAAAAAGGTGAACTCAAGG
TTAGTCATAAGCATTTTGAAGAAGCTTTCAAGAAAGTAAGATCATCTATATCAAAAAAGGATCAAATCATGTATGAACGTTTGCAGGAGT
CCCTCAGCCGGTGATGTCTCCAGCAGCCGGCTTAGAGGAGCTAGCCCATCAAGCCGGCAGAGAATCCCCCACACGCTCTGAAGGACCCAC
TTTCAGCTGGACACAGGCGCGGCCTCATGTAAACATTTTATTTTCAAATGAATGAGGCCAAGCTGAAGCTGAAGCTGAAGATTCTTCCCA

>In-frame_SUSD4_ENST00000343846_chr1_223536620_-_NVL_ENST00000361463_chr1_224468887_-_1232nt
CAGGTAAGACCGACAGTCCCGGAAGGGTCTTCCATTCCGAGGAGGCGCGCGCAGGCCGGGGAGGGGGAGTTGGTGCCTGGTGCAGCTCCC
CAAGGGAGAATTTTTTTTTTTTTTTTGACAGCGCAGAGAAATCTCACTGGGGACTGGGGCAGTAGGATCGATCCCAATCCCGAGGAAAAC
CAGAGAAGTAGCTGGGGGAGACGGTGCCACATTGTGAGATTCCCAGAGTGAAATGTATAGGCCCAGGGAAAAGTGTCTTCGCGGCCCCGA
GACGCGGGGAGGCTCTAGACTTTCCTGTGGTGGGCACAGCTGCTGAATCCCGGGGACCGGCGCGGAGCCAATGTGCGCTAACCCCTGCCC
TCCCTCCTGTCCTCCATCCCCCAGCACGCGCAGCATCCCACGGCGGCTGTTACTCAGTGCACCCGGCTCGGGGGAAGGCGGGGGACCTCG
CCGTGGGAAAGGGGGCGGGGGCCGCGCGGGGGAGGAACCAGGATGGAGCCTGGGAAGCCGAGGCGCCGGGTCCCAGAGCGGAGGAGGGGG
AGCGTGGCCCCCGAGCCCGGACAGACTGGCTTATTGTGGTGTTCCGCTTCTGGTTGCAGACTCTTGCAAGCTGGATGCCCTCTGTGGATG
AAAGATGTATCATGGAATGAACCCGAGCAATGGAGATGGATTTCTAGAGCAGCAGCAGCAGCAGCAGCAACCTCAGTCCCCCCAGAGACT
CTTGGCCGTGATCCTGTGGTTTCAGCTGGCGCTGTGCTTCGGCCCTGCACAGCTCACGGGCGGCTGTTGCAAATGAGTCCGGACTAAATT
TTATATCTGTCAAGGGCCCCGAATTACTAAACATGTATGTTGGTGAGAGTGAACGTGCTGTGCGACAAGTTTTTCAACGAGCCAAGAACT
CAGCACCCTGTGTGATATTCTTTGATGAAGTGGATGCTTTATGTCCTCGAAGATCAGACCGAGAGATATAATTGACCCTGCAATCCTGCG
CCCGGGCCGCCTGGACAAAACACTGTTTGTGGGTTTACCGCCCCCTGCAGATCGCCTTGCCATCTTAAAAACTATCACAAAAAATGGTAC
CAAACCACCACTGGATGCAGATGTAAATTTGGAAGCAATTGCTGGTGACCTTCGCTGTGATTGCTATACGGGCGCAGATCTCTCTGCTTT


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FusionGenePPI for SUSD4_NVL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SUSD4CNTNAP3, NNT, ATP12A, FAT1, LRP5, FRAS1, ITGAV, HSD17B8, NID2, ENTPD6, ARSK, LAMA5, GFPT2, KDELC2, TXNDC11, ITGA8, DHPS, NAGLU, CCDC85C, PLXNA2, PLXNA1, ITGA7, KIAA1467, CTSF, ADAMTS2, NLGN2, CACNA2D1, PAM, FUT11, IL17RA, POGLUT1, TOR3A, CERCAM, ARSB, MOXD1, PCOLCE2, MAN2A2, WDR34, HAPLN3, TCTN1, TXNDC16, ECE1, TUBB3, TUBA4A, ARSANVLTTF2, CRMP1, OSGEP, SIRT7, CUL3, MOV10, RPL14, NPM1, PRR11, ILF2, HSPB1, IFI16, CEP164, CEP19, UBE2I, RHOA, CLCN2, HNRNPU, RPL10, UBA1, KIF21A, GPATCH4, RRP8, PES1, MAK16, ZNF512, PLEKHO1, FGF8, MECP2, RBM34, DGCR8, ZNF71, RBM4, PPAN


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneNVLchr1:223536620chr1:224468887ENST00000281701-14231_220633857RPL5
TgeneNVLchr1:223536620chr1:224468887ENST00000340871-12211_220444668RPL5
TgeneNVLchr1:223536620chr1:224468887ENST00000391875-13221_220527751RPL5
TgeneNVLchr1:223536620chr1:224468887ENST00000469075-13221_220542766RPL5


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SUSD4_NVL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SUSD4_NVL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource