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Fusion gene ID: 36046 |
FusionGeneSummary for SRPK2_ZC3HC1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SRPK2_ZC3HC1 | Fusion gene ID: 36046 | Hgene | Tgene | Gene symbol | SRPK2 | ZC3HC1 | Gene ID | 6733 | 51530 |
| Gene name | SRSF protein kinase 2 | zinc finger C3HC-type containing 1 | |
| Synonyms | SFRSK2 | HSPC216|NIPA | |
| Cytomap | 7q22.3 | 7q32.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | SRSF protein kinase 2SFRS protein kinase 2SR protein kinase 2SR-protein-specific kinase 2serine kinase SRPK2serine/arginine-rich protein-specific kinase 2serine/arginine-rich splicing factor kinase 2serine/threonine-protein kinase SRPK2 | nuclear-interacting partner of ALKhematopoietic stem/progenitor cell protein 216nuclear interacting partner of anaplastic lymphoma kinase (ALK) | |
| Modification date | 20180523 | 20180529 | |
| UniProtAcc | P78362 | Q86WB0 | |
| Ensembl transtripts involved in fusion gene | ENST00000393651, ENST00000357311, ENST00000489828, ENST00000493638, | ENST00000358303, ENST00000360708, ENST00000311873, ENST00000481503, | |
| Fusion gene scores | * DoF score | 11 X 6 X 10=660 | 3 X 3 X 4=36 |
| # samples | 19 | 4 | |
| ** MAII score | log2(19/660*10)=-1.79646660591487 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SRPK2 [Title/Abstract] AND ZC3HC1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SRPK2 | GO:0000245 | spliceosomal complex assembly | 9472028 |
| Hgene | SRPK2 | GO:0006468 | protein phosphorylation | 9472028 |
| Hgene | SRPK2 | GO:0008284 | positive regulation of cell proliferation | 18559500 |
| Hgene | SRPK2 | GO:0008380 | RNA splicing | 9472028 |
| Hgene | SRPK2 | GO:0035556 | intracellular signal transduction | 9472028 |
| Hgene | SRPK2 | GO:0045070 | positive regulation of viral genome replication | 20498328 |
| Hgene | SRPK2 | GO:0045071 | negative regulation of viral genome replication | 12417631 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | KIRP | TCGA-5P-A9JZ-01A | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000393651 | ENST00000358303 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| Frame-shift | ENST00000393651 | ENST00000360708 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| Frame-shift | ENST00000393651 | ENST00000311873 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| Frame-shift | ENST00000393651 | ENST00000481503 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| Frame-shift | ENST00000357311 | ENST00000358303 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| Frame-shift | ENST00000357311 | ENST00000360708 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| Frame-shift | ENST00000357311 | ENST00000311873 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| Frame-shift | ENST00000357311 | ENST00000481503 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| In-frame | ENST00000489828 | ENST00000358303 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| In-frame | ENST00000489828 | ENST00000360708 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| In-frame | ENST00000489828 | ENST00000311873 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| In-frame | ENST00000489828 | ENST00000481503 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| intron-3CDS | ENST00000493638 | ENST00000358303 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| intron-3CDS | ENST00000493638 | ENST00000360708 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| intron-3CDS | ENST00000493638 | ENST00000311873 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
| intron-3CDS | ENST00000493638 | ENST00000481503 | SRPK2 | chr7 | 104800954 | - | ZC3HC1 | chr7 | 129688984 | - |
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FusionProtFeatures for SRPK2_ZC3HC1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SRPK2 | ZC3HC1 |
| Serine/arginine-rich protein-specific kinase whichspecifically phosphorylates its substrates at serine residueslocated in regions rich in arginine/serine dipeptides, known as RSdomains and is involved in the phosphorylation of SR splicingfactors and the regulation of splicing. Promotes neuronalapoptosis by up-regulating cyclin-D1 (CCND1) expression. This isdone by the phosphorylation of SRSF2, leading to the suppressionof p53/TP53 phosphorylation thereby relieving the repressiveeffect of p53/TP53 on cyclin-D1 (CCND1) expression. PhosphorylatesACIN1, and redistributes it from the nuclear speckles to thenucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complexformation via the phosphorylation of DDX23/PRP28. Can mediatehepatitis B virus (HBV) core protein phosphorylation. Plays anegative role in the regulation of HBV replication through amechanism not involving the phosphorylation of the core proteinbut by reducing the packaging efficiency of the pregenomic RNA(pgRNA) without affecting the formation of the viral coreparticles. {ECO:0000269|PubMed:12134018,ECO:0000269|PubMed:16122776, ECO:0000269|PubMed:18425142,ECO:0000269|PubMed:18559500, ECO:0000269|PubMed:19592491,ECO:0000269|PubMed:21056976, ECO:0000269|PubMed:21157427,ECO:0000269|PubMed:9472028}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for SRPK2_ZC3HC1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000358303_chr7_129688984_-_650aa MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWG HFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKS NYQGLPVRCVKSIIRQEGHVCHIPVSXWITPSGTTFIGIYKQRSLLXQSGNIFFFEMGRXALXAVSTRLCKIWLGHSGMXYAQVLXLSSF SLCQFTTSFXLXQIXATMCXAEESLVYCPXEVLFLARQPIPRPIWDVAPGXACYSCXXIPRSFSKPLSLGPPASFPKAGGLENYVLDRRQ DQSSPTLAXRXTXSPNXXEKNYNQIRLRHPSPRHCLYSLCVWLGVXFLFGIHAALPDNMFAMYEEGGALGLPADXIVHDXPGCILWPDQL PNPRPXGATRALTSGAXISSEDDDPEPGCHFLPRLRAGXKEPWSHCLSNSELGLFQSCXPSXARGCXPHHQNSPSDPKHGNRRHPWPGGT IXPSAESQASSPLLLQQFGHIFPKLLXSHLSAXRLVPLGEYHTWQRKQGEWWNXTRCQRPSRARLESSADHPLGAQTVXPASXNGLHESL >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000360708_chr7_129688984_-_579aa MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWG HFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKS NYQGLPVRCVKSIIRQEGHVCHIPVSXWITPSGTTFIGIYKQRSLLXQSGNIFFFEMGRXALXAVSTRLCKIWLGHSGMXYAQVLXLSSF SLCQFTTSFXLXQIXATMCXAEESLVYCPXEVLFLARQPIPRPIWDVAPGXACYSCXXIPRSFSKPLSLGPPASFPKAGGLENYVLDRRQ DQSSPTLAXRXTXSPNXXEKNYNQIRLRHPSPRHCLYSLCVWLGVXFLFGIHAALPDNMFAMYEEGGALGLPADXIVHDXPGCILWPDQL PNPRPXGATRALTSGAXISSEDDDPEPGCHFLPRLRAGHIFPKLLXSHLSAXRLVPLGEYHTWQRKQGEWWNXTRCQRPSRARLESSADH >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000311873_chr7_129688984_-_650aa MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWG HFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKS NYQGLPVRCVKSIIRQEGHVCHIPVSXWITPSGTTFIGIYKQRSLLXQSGNIFFFEMGRXALXAVSTRLCKIWLGHSGMXYAQVLXLSSF SLCQFTTSFXLXQIXATMCXAEESLVYCPXEVLFLARQPIPRPIWDVAPGXACYSCXXIPRSFSKPLSLGPPASFPKAGGLENYVLDRRQ DQSSPTLAXRXTXSPNXXEKNYNQIRLRHPSPRHCLYSLCVWLGVXFLFGIHAALPDNMFAMYEEGGALGLPADXIVHDXPGCILWPDQL PNPRPXGATRALTSGAXISSEDDDPEPGCHFLPRLRAGXKEPWSHCLSNSELGLFQSCXPSXARGCXPHHQNSPSDPKHGNRRHPWPGGT IXPSAESQASSPLLLQQFGHIFPKLLXSHLSAXRLVPLGEYHTWQRKQGEWWNXTRCQRPSRARLESSADHPLGAQTVXPASXNGLHESL >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000481503_chr7_129688984_-_607aa MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPPPLPDPTPPEPEEEILGSDDEEQEDPADYCKGGYHPVKIGDLFNGRYHVIRKLGWG HFSTVWLCWDMQGKRFVAMKVVKSAQHYTETALDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKS NYQGLPVRCVKSIIRQEGHVCHIPVSXWITPSGTTFIGIYKQRSLLXQSGNIFFFEMGRXALXAVSTRLCKIWLGHSGMXYAQVLXLSSF SLCQFTTSFXLXQIXATMCXAEESLVYCPXEVLFLARQPIPRPIWDVAPGXACYSCXXIPRSFSKPLSLGPPASFPKAGGLENYVLDRRQ DQSSPTLAXRXTXSPNXXEKNYNQIRLRHPSPRHCLYSLCVWLGVXLPNPRPXGATRALTSGAXISSEDDDPEPGCHFLPRLRAGXKEPW SHCLSNSELGLFQSCXPSXARGCXPHHQNSPSDPKHGNRRHPWPGGTIXPSAESQASSPLLLQQFGHIFPKLLXSHLSAXRLVPLGEYHT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000358303_chr7_129688984_-_1951nt ATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACCA CCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCCT GCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGGG CACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGAG ACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGAC GACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATCC AACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCACC CCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTAA GCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTTT TCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATGA GAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCCT AGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACAA GATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCCA AGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGTTCCTCTTTGGAATCCATGCAGCTCTCCCTGATAACATGTTC GCAATGTATGAGGAAGGTGGGGCTCTGGGGCTTCCAGCAGATTGAATCGTCCATGACTGACCTGGATGCATCCTTTGGCCTGACCAGCTC CCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTACCTCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCAC TTTCTCCCCAGGCTCAGAGCAGGCTGAAAAGAGCCCTGGTCCCATTGTCTCTCGAACTCGGAGCTGGGACTCTTCCAGTCCTGTTGACCG TCCTGAGCCAGAGGCTGCTAGCCCCACCACCAGAACTCGCCCAGTGACCCGAAGCATGGGAACAGGAGACACCCCTGGCCTGGAGGTACC ATCTAGCCCTCTGCGGAAAGCCAAGCGAGCTCGCCTCTGCTCCTCCAGCAGTTCGGACACATCTTCCCGAAGCTTCTTTGATCCCACCTC TCAGCATAGAGACTGGTGCCCTTGGGTGAATATCACACTTGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCCC AGCAGAGCCAGGCTGGAAAGCAGTGCTGACCATCCTCTTGGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCTC >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000360708_chr7_129688984_-_1738nt ATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACCA CCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCCT GCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGGG CACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGAG ACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGAC GACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATCC AACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCACC CCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTAA GCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTTT TCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATGA GAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCCT AGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACAA GATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCCA AGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGTTCCTCTTTGGAATCCATGCAGCTCTCCCTGATAACATGTTC GCAATGTATGAGGAAGGTGGGGCTCTGGGGCTTCCAGCAGATTGAATCGTCCATGACTGACCTGGATGCATCCTTTGGCCTGACCAGCTC CCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTACCTCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCAC TTTCTCCCCAGGCTCAGAGCAGGACACATCTTCCCGAAGCTTCTTTGATCCCACCTCTCAGCATAGAGACTGGTGCCCTTGGGTGAATAT CACACTTGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCCCAGCAGAGCCAGGCTGGAAAGCAGTGCTGACCAT CCTCTTGGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCTCTGAGAAATCAAGGAAAGTATTCCGAATATTTCG >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000311873_chr7_129688984_-_1951nt ATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACCA CCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCCT GCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGGG CACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGAG ACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGAC GACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATCC AACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCACC CCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTAA GCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTTT TCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATGA GAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCCT AGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACAA GATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCCA AGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGTTCCTCTTTGGAATCCATGCAGCTCTCCCTGATAACATGTTC GCAATGTATGAGGAAGGTGGGGCTCTGGGGCTTCCAGCAGATTGAATCGTCCATGACTGACCTGGATGCATCCTTTGGCCTGACCAGCTC CCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTACCTCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCAC TTTCTCCCCAGGCTCAGAGCAGGCTGAAAAGAGCCCTGGTCCCATTGTCTCTCGAACTCGGAGCTGGGACTCTTCCAGTCCTGTTGACCG TCCTGAGCCAGAGGCTGCTAGCCCCACCACCAGAACTCGCCCAGTGACCCGAAGCATGGGAACAGGAGACACCCCTGGCCTGGAGGTACC ATCTAGCCCTCTGCGGAAAGCCAAGCGAGCTCGCCTCTGCTCCTCCAGCAGTTCGGACACATCTTCCCGAAGCTTCTTTGATCCCACCTC TCAGCATAGAGACTGGTGCCCTTGGGTGAATATCACACTTGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCCC AGCAGAGCCAGGCTGGAAAGCAGTGCTGACCATCCTCTTGGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCTC >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000481503_chr7_129688984_-_1822nt ATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACCA CCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCCT GCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGGG CACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGAG ACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGAC GACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATCC AACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCACC CCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTAA GCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTTT TCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATGA GAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCCT AGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACAA GATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCCA AGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGCTCCCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTACC TCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCACTTTCTCCCCAGGCTCAGAGCAGGCTGAAAAGAGCCCTGG TCCCATTGTCTCTCGAACTCGGAGCTGGGACTCTTCCAGTCCTGTTGACCGTCCTGAGCCAGAGGCTGCTAGCCCCACCACCAGAACTCG CCCAGTGACCCGAAGCATGGGAACAGGAGACACCCCTGGCCTGGAGGTACCATCTAGCCCTCTGCGGAAAGCCAAGCGAGCTCGCCTCTG CTCCTCCAGCAGTTCGGACACATCTTCCCGAAGCTTCTTTGATCCCACCTCTCAGCATAGAGACTGGTGCCCTTGGGTGAATATCACACT TGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCCCAGCAGAGCCAGGCTGGAAAGCAGTGCTGACCATCCTCTT GGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCTCTGAGAAATCAAGGAAAGTATTCCGAATATTTCGGCAGTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000358303_chr7_129688984_-_2510nt GTTGGAGTGGGCCCTGTGCCTCTGCTGTCTCCTACTGCTAACGAGTGAACAACCAAGGCGATGGGCTGTAGGATGTTGATACATCTGAGG GGCCAGATGGCCACCATATCAGGGAAAGCCAATGTGTTTTGAAAAATATGCAAATGTTCAATAAGAAATCAAGCAGAAGATTGAGCTGCT GATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACC ACCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCC TGCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGG GCACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGA GACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGA CGACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATC CAACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCAC CCCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTA AGCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTT TTCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATG AGAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCC TAGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACA AGATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCC AAGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGTTCCTCTTTGGAATCCATGCAGCTCTCCCTGATAACATGTT CGCAATGTATGAGGAAGGTGGGGCTCTGGGGCTTCCAGCAGATTGAATCGTCCATGACTGACCTGGATGCATCCTTTGGCCTGACCAGCT CCCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTACCTCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCA CTTTCTCCCCAGGCTCAGAGCAGGCTGAAAAGAGCCCTGGTCCCATTGTCTCTCGAACTCGGAGCTGGGACTCTTCCAGTCCTGTTGACC GTCCTGAGCCAGAGGCTGCTAGCCCCACCACCAGAACTCGCCCAGTGACCCGAAGCATGGGAACAGGAGACACCCCTGGCCTGGAGGTAC CATCTAGCCCTCTGCGGAAAGCCAAGCGAGCTCGCCTCTGCTCCTCCAGCAGTTCGGACACATCTTCCCGAAGCTTCTTTGATCCCACCT CTCAGCATAGAGACTGGTGCCCTTGGGTGAATATCACACTTGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCC CAGCAGAGCCAGGCTGGAAAGCAGTGCTGACCATCCTCTTGGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCT CTGAGAAATCAAGGAAAGTATTCCGAATATTTCGGCAGTGGGAATCTCTGTGCTCATGCTGAAGATACTCCAGCGCCTTCCTGGAGATAG CTGGAATGAGAGTGACTTTTTGAAAAATTAAGGCTGAGTTCCTTTCGGTCAGCTGACACTAAGTTTTTCCTGTTCTGGGTTAATCATAAG GAGCCCCCTGCCATAGCAAAGGCAGTGAGTGTCAACTATCTGCATCTGGCTGAGAGAGACCCGTTTCCTTTCAGGGATGTGGACAGGGTA AGGGCAGCAAGCATGGTTCTGTTAAAGGAGTGTGGGATTAACAGACTAGAAGGAAGACTAAGGACCTGACCACCCATTTCAGCATCTTCA >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000360708_chr7_129688984_-_2291nt GTTGGAGTGGGCCCTGTGCCTCTGCTGTCTCCTACTGCTAACGAGTGAACAACCAAGGCGATGGGCTGTAGGATGTTGATACATCTGAGG GGCCAGATGGCCACCATATCAGGGAAAGCCAATGTGTTTTGAAAAATATGCAAATGTTCAATAAGAAATCAAGCAGAAGATTGAGCTGCT GATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACC ACCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCC TGCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGG GCACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGA GACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGA CGACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATC CAACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCAC CCCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTA AGCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTT TTCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATG AGAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCC TAGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACA AGATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCC AAGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGTTCCTCTTTGGAATCCATGCAGCTCTCCCTGATAACATGTT CGCAATGTATGAGGAAGGTGGGGCTCTGGGGCTTCCAGCAGATTGAATCGTCCATGACTGACCTGGATGCATCCTTTGGCCTGACCAGCT CCCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTACCTCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCA CTTTCTCCCCAGGCTCAGAGCAGGACACATCTTCCCGAAGCTTCTTTGATCCCACCTCTCAGCATAGAGACTGGTGCCCTTGGGTGAATA TCACACTTGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCCCAGCAGAGCCAGGCTGGAAAGCAGTGCTGACCA TCCTCTTGGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCTCTGAGAAATCAAGGAAAGTATTCCGAATATTTC GGCAGTGGGAATCTCTGTGCTCATGCTGAAGATACTCCAGCGCCTTCCTGGAGATAGCTGGAATGAGAGTGACTTTTTGAAAAATTAAGG CTGAGTTCCTTTCGGTCAGCTGACACTAAGTTTTTCCTGTTCTGGGTTAATCATAAGGAGCCCCCTGCCATAGCAAAGGCAGTGAGTGTC AACTATCTGCATCTGGCTGAGAGAGACCCGTTTCCTTTCAGGGATGTGGACAGGGTAAGGGCAGCAAGCATGGTTCTGTTAAAGGAGTGT GGGATTAACAGACTAGAAGGAAGACTAAGGACCTGACCACCCATTTCAGCATCTTCAATGTGGAGCAGTGTTCTGAGGACTCTTCTATCC >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000311873_chr7_129688984_-_2503nt GTTGGAGTGGGCCCTGTGCCTCTGCTGTCTCCTACTGCTAACGAGTGAACAACCAAGGCGATGGGCTGTAGGATGTTGATACATCTGAGG GGCCAGATGGCCACCATATCAGGGAAAGCCAATGTGTTTTGAAAAATATGCAAATGTTCAATAAGAAATCAAGCAGAAGATTGAGCTGCT GATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACC ACCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCC TGCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGG GCACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGA GACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGA CGACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATC CAACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCAC CCCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTA AGCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTT TTCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATG AGAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCC TAGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACA AGATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCC AAGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGTTCCTCTTTGGAATCCATGCAGCTCTCCCTGATAACATGTT CGCAATGTATGAGGAAGGTGGGGCTCTGGGGCTTCCAGCAGATTGAATCGTCCATGACTGACCTGGATGCATCCTTTGGCCTGACCAGCT CCCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTACCTCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCA CTTTCTCCCCAGGCTCAGAGCAGGCTGAAAAGAGCCCTGGTCCCATTGTCTCTCGAACTCGGAGCTGGGACTCTTCCAGTCCTGTTGACC GTCCTGAGCCAGAGGCTGCTAGCCCCACCACCAGAACTCGCCCAGTGACCCGAAGCATGGGAACAGGAGACACCCCTGGCCTGGAGGTAC CATCTAGCCCTCTGCGGAAAGCCAAGCGAGCTCGCCTCTGCTCCTCCAGCAGTTCGGACACATCTTCCCGAAGCTTCTTTGATCCCACCT CTCAGCATAGAGACTGGTGCCCTTGGGTGAATATCACACTTGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCC CAGCAGAGCCAGGCTGGAAAGCAGTGCTGACCATCCTCTTGGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCT CTGAGAAATCAAGGAAAGTATTCCGAATATTTCGGCAGTGGGAATCTCTGTGCTCATGCTGAAGATACTCCAGCGCCTTCCTGGAGATAG CTGGAATGAGAGTGACTTTTTGAAAAATTAAGGCTGAGTTCCTTTCGGTCAGCTGACACTAAGTTTTTCCTGTTCTGGGTTAATCATAAG GAGCCCCCTGCCATAGCAAAGGCAGTGAGTGTCAACTATCTGCATCTGGCTGAGAGAGACCCGTTTCCTTTCAGGGATGTGGACAGGGTA AGGGCAGCAAGCATGGTTCTGTTAAAGGAGTGTGGGATTAACAGACTAGAAGGAAGACTAAGGACCTGACCACCCATTTCAGCATCTTCA >In-frame_SRPK2_ENST00000489828_chr7_104800954_-_ZC3HC1_ENST00000481503_chr7_129688984_-_2341nt GTTGGAGTGGGCCCTGTGCCTCTGCTGTCTCCTACTGCTAACGAGTGAACAACCAAGGCGATGGGCTGTAGGATGTTGATACATCTGAGG GGCCAGATGGCCACCATATCAGGGAAAGCCAATGTGTTTTGAAAAATATGCAAATGTTCAATAAGAAATCAAGCAGAAGATTGAGCTGCT GATGTCAGTTAACTCTGAGAAGTCGTCCTCTTCAGAAAGGCCGGAGCCTCAACAGAAAGCTCCTTTAGTTCCTCCTCCTCCACCGCCACC ACCACCACCACCGCCACCTTTGCCAGACCCCACACCCCCGGAGCCAGAGGAGGAGATCCTGGGATCAGATGATGAGGAGCAAGAGGACCC TGCGGACTACTGCAAAGGTGGATATCATCCAGTGAAAATTGGAGACCTCTTCAATGGCCGGTATCATGTTATTAGAAAGCTTGGATGGGG GCACTTCTCTACTGTCTGGCTGTGCTGGGATATGCAGGGGAAAAGATTTGTTGCAATGAAAGTTGTAAAAAGTGCCCAGCATTATACGGA GACAGCCTTGGATGAAATAAAATTGCTCAAATGTGTTCGAGAAAGTGATCCCAGTGACCCAAACAAAGACATGGTGGTCCAGCTCATTGA CGACTTCAAGATTTCAGGCATGAATGGGATACATGTCTGCATGGTCTTCGAAGTACTTGGCCACCATCTCCTCAAGTGGATCATCAAATC CAACTATCAAGGCCTCCCAGTACGTTGTGTGAAGAGTATCATTCGACAGGAAGGACACGTCTGCCACATCCCAGTCAGTTAATGGATCAC CCCAAGCGGAACAACCTTCATTGGAATCTACAAGCAAAGAAGCCTTCTTTAGCAGAGTGGAAACATTTTCTTCTTTGAAATGGGCAGGTA AGCCCTTTGAGCTGTCTCCACTCGTCTGTGCAAAATATGGCTGGGTCACAGTGGAATGTGATATGCTCAAGTGCTCTAGCTGTCAAGCTT TTCTCTGTGCCAGTTTACAACCAGCTTTTGACTTTGACAGATATAAGCAACGATGTGCTGAGCTGAAGAAAGCCTTGTGTACTGCCCATG AGAAGTTCTGTTTCTGGCCAGACAGCCCATCCCCAGACCGATTTGGGATGTTGCCCCTGGATGAGCCTGCTATTCTTGTTAGTGAATTCC TAGATCGTTTTCAAAGCCTTTGTCACTTGGACCTCCAGCTTCCTTCCCTAAGGCCGGAGGACTTGAAAACTATGTGCTTGACAGAAGACA AGATCAGTCTTCTCCTACACTTGCTTGAAGATGAACTTGATCACCGAACTGATGAGAGAAAAACTACAATCAAATTAGGCTCAGACATCC AAGTCCACGTCACTGCCTGTATTCTCTCTGTGTGTGGCTGGGCGTGTAGCTCCCCAATCCCAGGCCTTGAGGGGCGACCAGAGCGCTTAC CTCTGGTGCCTGAATCTCCTCGGAGGATGATGACCCGGAGCCAGGATGCCACTTTCTCCCCAGGCTCAGAGCAGGCTGAAAAGAGCCCTG GTCCCATTGTCTCTCGAACTCGGAGCTGGGACTCTTCCAGTCCTGTTGACCGTCCTGAGCCAGAGGCTGCTAGCCCCACCACCAGAACTC GCCCAGTGACCCGAAGCATGGGAACAGGAGACACCCCTGGCCTGGAGGTACCATCTAGCCCTCTGCGGAAAGCCAAGCGAGCTCGCCTCT GCTCCTCCAGCAGTTCGGACACATCTTCCCGAAGCTTCTTTGATCCCACCTCTCAGCATAGAGACTGGTGCCCTTGGGTGAATATCACAC TTGGCAAAGAAAGCAGGGAGAATGGTGGAACTGAACCAGATGCCAGCGCCCCAGCAGAGCCAGGCTGGAAAGCAGTGCTGACCATCCTCT TGGCGCACAAACAGTCTAGCCAGCCAGCTGAAACGGACTCCATGAGTCTCTCTGAGAAATCAAGGAAAGTATTCCGAATATTTCGGCAGT GGGAATCTCTGTGCTCATGCTGAAGATACTCCAGCGCCTTCCTGGAGATAGCTGGAATGAGAGTGACTTTTTGAAAAATTAAGGCTGAGT TCCTTTCGGTCAGCTGACACTAAGTTTTTCCTGTTCTGGGTTAATCATAAGGAGCCCCCTGCCATAGCAAAGGCAGTGAGTGTCAACTAT CTGCATCTGGCTGAGAGAGACCCGTTTCCTTTCAGGGATGTGGACAGGGTAAGGGCAGCAAGCATGGTTCTGTTAAAGGAGTGTGGGATT AACAGACTAGAAGGAAGACTAAGGACCTGACCACCCATTTCAGCATCTTCAATGTGGAGCAGTGTTCTGAGGACTCTTCTATCCTAGGAC |
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FusionGenePPI for SRPK2_ZC3HC1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SRPK2 | U2AF2, RNPS1, SRSF1, SRSF3, SRSF2, SRSF5, SRSF6, SNRNP70, LUC7L3, SRPK1, VAV2, ARRB2, CUL3, APP, ESR1, BARD1, U2AF1, DDX46, RBM23, RBM39, PRPF38A, CTNNBL1, SNIP1, ACIN1, ARGLU1, SNRNP27, YTHDC1, DDX21, LUC7L, SRRM1, PABPC4, PRPF4B, SRRM2, PNN, SRPK2, SNRPD1, EIF4A3, HNRNPM, NOP2, DHX15, SNRPA, SNRPC, PCBP1, BCLAF1, RBBP6, PABPC1, C1orf35, DROSHA, LUC7L2, SRSF8, HNRNPC, RBM8A, MAGOH, SRSF7, TJP2, ALMS1, HNRNPCL1, CLASRP, DIDO1, DDX50, SNRPB, DGCR8, THRAP3, HNRNPH2, DDX39A, DDX39B, CPSF6, SON, NUDT21, NSG1, CHTOP, CDK13, FOXN3, EIF1AY, CHD2, TNFRSF10C, CASK, AURKA, CHUK, ARPC1B, UBD, NCK2, AHCYL1, TLE4, ERN1, DNAJC8, GABARAP, ZRANB2, TDP2, PAK4, ABL1, POLB, NELFE, ERCC3, MDK, PSMA3, DDX6, PTBP1, APEX1, GTF2E1, SRI, YWHAB, RPL22, MAGEB1, CBX5, CLK1, CLK3, CDK7, ADPRH, TPD52, RWDD2B, YPEL3, FGF12, WDR5, PPIA, RPL41, TRA2B, RNF4, MRPS6, PRKAA1, SRSF9, IFIT5, MPP3, TCOF1, TRA2A, DHX8, DRAP1, BRD3, SEC23B, HMGN3, ZRSR2, ENOX2, SNRNP35, C4orf46, C17orf85, TAF7L, FAM76B, ATAT1, ARL6IP4, AMMECR1L, CSAG1, RSRC2, NPM2, CAND1, LCA5, FAM90A1, MAPKAPK5, CCDC28A, ARHGAP12, CHERP, GPR114, DAW1, CLDN19, MARCH10, LRRN4CL, DBF4B, TNIP2, MCOLN3, EPS8L3, C16orf78, SDR42E1, TRIM41, SREK1, SRSF12, TTN, RTF1, RIT1, C18orf25, EVI5L, RPL39L, CCDC97, PELI1, NGLY1, RSRC1, EGLN2, UBE2E2, ALKBH3, YPEL2, RBM15, RIT2, VRK1, VIMP, CCM2, RSRP1, HIRIP3, LCE3D, NSRP1, GABARAPL1, KCNN2, CDC42EP4, EPB41L1, OCEL1, ZMAT4, EPB41L4A, PDE7B, NXT2, APOBEC3C, HOMER3, CBLN4, NSMCE4A, SLAIN2, NUP50, BAIAP2, DRG1, NOP16, PPIL1, HBS1L, MAB21L2, SUPT16H, SNURF, CACNG2, STON1, AES, CLK2, ZSCAN9, FXR2, LUZP4, BMI1, PPM1G, PRPF8, NTRK1, C5orf42, ACTB, ACTG1, ADAMTS18, AKAP13, ALDOA, ALPL, ANK3, ANKFY1, ANKRD35, AP1M1, KIAA1244, ARSG, ASL, BAG3, BAZ1A, BCL9L, BUD13, EFCAB12, ELP6, CADPS2, CALCOCO1, CAMSAP1, CARD11, CARHSP1, MTCL1, CCDC86, CCDC88B, CDK12, CEP170, CHD1L, CHEK2, CLASP1, CLASP2, CLCNKA, CLU, CPSF7, CRTC1, YBX3, DCAF10, DDX3X, DNAH6, DNAH9, DOCK3, ECT2, EED, EIF3A, EIF4B, EIF4G1, ELAVL3, ENSA, EPB41L4B, EPM2A, EPS8L1, ERBB3, ERC1, F5, AMER1, FAM179B, FAM43A, NXPE4, FBXO24, FCHO1, FGFR3, FIP1L1, FMNL1, GBF1, GCC2, GGCX, GHR, GLRA4, GLTSCR2, GNGT2, GSE1, GTPBP4, GXYLT2, HERC3, HIST1H2BK, HIVEP1, HMCN2, HMGA1, HMGN2, HMGXB4, HNRNPA1, HNRNPA3, HNRNPK, HTATSF1, IRS2, ISLR, JMJD1C, KANK2, KHDRBS1, KIF11, KRT78, LBR, LDHC, LINC00322, LMNA, LMNB1, LMO7, LRRC34, LRRC52, MACF1, MAP1S, MAP4, MAP7, MAP7D1, MAPKAPK3, MAPRE1, MAST2, MATR3, MDC1, MFSD10, MIB2, MIPOL1, ZAK, MMP23B, MYCBP2, MYLIP, MYO18B, MYO1E, MZT2B, NADK, NAGK, NCL, NGDN, NKAP, NOLC1, NSUN5P2, NTHL1, NXF1, OTOF, PALLD, PCF11, PDCL3, PHF6, PHLDB1, PKD1L2, PLEKHA5, PNMAL2, POLDIP3, PPHLN1, PPP1R13L, PRPF38B, PRRC2A, PRRC2B, PRRC2C, PSMD13, PTPN22, RABEP1, RASGRF1, RBM15B, RBM19, RBMX, RIPK3, RNF219, RPL13, RPL34, RPL37, RPLP2, RPS26, RRM2B, RRP1, RRP1B, RSL1D1, RXFP1, S100A4, SAFB, SART1, SBK1, SCAF1, SDK2, SEC16B, SERPING1, PNISR, SGPL1, SIPA1L3, SLC13A2, SLC17A6, SLFN5, SLTM, SMCHD1, SPDEF, SPEN, SRC, SRSF11, SRXN1, SYCP2, TCEANC2, TMEM57, TMPO, TMPRSS11A, TMSB10, TNFAIP8L2, TNS3, TOP1, TRIP12, TUBA1B, TXN, UBR4, UPF3B, USP36, USP39, VAC14, VSTM2L, WDR24, WDR70, XRCC5, YRDC, YTHDC2, ZC3H13, ZC3H18, ZCCHC17, ZDHHC5, ZFC3H1, ZFHX4, ZFP91, ZMYM4, ZNF140, ZNF234, ZNF529, ZNF592, ZNF593, ZNF616, FOXK2, FOXL2, FOXQ1, YBX1, AKT1, INO80B, TRIM25 | ZC3HC1 | CCNB1, SKP1, CUL1, RBX1, TNFSF11, PDPK1, TSC22D1, ALK, APP, EHD4, GTF3C4, AASDHPPT, HNRNPA1, PFKL, RPL38, TRIP13, FZR1, MAPK3, MAPK1, FAM188A, ATP6V1C2, GRN, HIST1H2BG, CDC5L, YWHAE, NXF2B, PLK1, SASS6, GPX7, TPR, FAM19A3, SRBD1, ETNPPL, SALL2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SRPK2_ZC3HC1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SRPK2_ZC3HC1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ZC3HC1 | C1956346 | Coronary Artery Disease | 1 | CTD_human |
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