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Fusion gene ID: 35723 |
FusionGeneSummary for SPNS1_PRKCB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SPNS1_PRKCB | Fusion gene ID: 35723 | Hgene | Tgene | Gene symbol | SPNS1 | PRKCB | Gene ID | 83985 | 5579 |
| Gene name | sphingolipid transporter 1 (putative) | protein kinase C beta | |
| Synonyms | HSpin1|LAT|PP2030|SPIN1|SPINL|nrs | PKC-beta|PKCB|PRKCB1|PRKCB2 | |
| Cytomap | 16p11.2 | 16p12.2-p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein spinster homolog 1SPNS sphingolipid transporter 1 (putative)spinster homolog 1spinster-like protein 1 | protein kinase C beta typePKC-Bprotein kinase C, beta 1 polypeptide | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9H2V7 | P05771 | |
| Ensembl transtripts involved in fusion gene | ENST00000565975, ENST00000311008, ENST00000323081, ENST00000334536, ENST00000352260, ENST00000561868, | ENST00000321728, ENST00000303531, ENST00000482000, ENST00000498058, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 13 X 9 X 10=1170 |
| # samples | 2 | 14 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(14/1170*10)=-3.0630097975258 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SPNS1 [Title/Abstract] AND PRKCB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | PRKCB | GO:0035408 | histone H3-T6 phosphorylation | 20228790 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-83-5908-01A | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000565975 | ENST00000321728 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| In-frame | ENST00000565975 | ENST00000303531 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000565975 | ENST00000482000 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000565975 | ENST00000498058 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| In-frame | ENST00000311008 | ENST00000321728 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| In-frame | ENST00000311008 | ENST00000303531 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000311008 | ENST00000482000 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000311008 | ENST00000498058 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| In-frame | ENST00000323081 | ENST00000321728 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| In-frame | ENST00000323081 | ENST00000303531 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000323081 | ENST00000482000 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000323081 | ENST00000498058 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| In-frame | ENST00000334536 | ENST00000321728 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| In-frame | ENST00000334536 | ENST00000303531 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000334536 | ENST00000482000 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 5CDS-intron | ENST00000334536 | ENST00000498058 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| intron-3CDS | ENST00000352260 | ENST00000321728 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| intron-3CDS | ENST00000352260 | ENST00000303531 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| intron-intron | ENST00000352260 | ENST00000482000 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| intron-intron | ENST00000352260 | ENST00000498058 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 3UTR-3CDS | ENST00000561868 | ENST00000321728 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 3UTR-3CDS | ENST00000561868 | ENST00000303531 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 3UTR-intron | ENST00000561868 | ENST00000482000 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
| 3UTR-intron | ENST00000561868 | ENST00000498058 | SPNS1 | chr16 | 28986878 | + | PRKCB | chr16 | 23999829 | + |
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FusionProtFeatures for SPNS1_PRKCB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SPNS1 | PRKCB |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 50_70 | 102 | 529 | Transmembrane | Helical |
| Hgene | SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 50_70 | 102 | 477 | Transmembrane | Helical |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000303531 | + | 1 | 17 | 173_260 | 68 | 674 | Domain | C2 |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000303531 | + | 1 | 17 | 342_600 | 68 | 674 | Domain | Protein kinase |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000303531 | + | 1 | 17 | 601_671 | 68 | 674 | Domain | Note=AGC-kinase C-terminal |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000321728 | + | 1 | 17 | 173_260 | 68 | 672 | Domain | C2 |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000321728 | + | 1 | 17 | 342_600 | 68 | 672 | Domain | Protein kinase |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000321728 | + | 1 | 17 | 601_671 | 68 | 672 | Domain | Note=AGC-kinase C-terminal |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000498058 | + | 0 | 2 | 173_260 | -32 | 58 | Domain | C2 |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000498058 | + | 0 | 2 | 342_600 | -32 | 58 | Domain | Protein kinase |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000498058 | + | 0 | 2 | 601_671 | -32 | 58 | Domain | Note=AGC-kinase C-terminal |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000303531 | + | 1 | 17 | 348_356 | 68 | 674 | Nucleotide binding | ATP |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000321728 | + | 1 | 17 | 348_356 | 68 | 672 | Nucleotide binding | ATP |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000498058 | + | 0 | 2 | 348_356 | -32 | 58 | Nucleotide binding | ATP |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000303531 | + | 1 | 17 | 101_151 | 68 | 674 | Zinc finger | Phorbol-ester/DAG-type 2 |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000321728 | + | 1 | 17 | 101_151 | 68 | 672 | Zinc finger | Phorbol-ester/DAG-type 2 |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000498058 | + | 0 | 2 | 101_151 | -32 | 58 | Zinc finger | Phorbol-ester/DAG-type 2 |
| Tgene | >PRKCB | chr16:28986878 | chr16:23999829 | ENST00000498058 | + | 0 | 2 | 36_86 | -32 | 58 | Zinc finger | Phorbol-ester/DAG-type 1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 127_147 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 160_180 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 187_207 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 218_238 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 278_298 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 323_343 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 357_377 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 381_401 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 421_441 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 465_485 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000311008 | + | 2 | 12 | 98_118 | 102 | 529 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 127_147 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 160_180 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 187_207 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 218_238 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 278_298 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 323_343 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 357_377 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 381_401 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 421_441 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 465_485 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 50_70 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000323081 | + | 3 | 13 | 98_118 | 29 | 456 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 127_147 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 160_180 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 187_207 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 218_238 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 278_298 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 323_343 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 357_377 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 381_401 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 421_441 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 465_485 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000334536 | + | 2 | 11 | 98_118 | 102 | 477 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 127_147 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 160_180 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 187_207 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 218_238 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 278_298 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 323_343 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 357_377 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 381_401 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 421_441 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 465_485 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 50_70 | -113 | 455 | Transmembrane | Helical |
| Hgene | >SPNS1 | chr16:28986878 | chr16:23999829 | ENST00000352260 | + | 1 | 10 | 98_118 | -113 | 455 | Transmembrane | Helical |
| Tgene | PRKCB | chr16:28986878 | chr16:23999829 | ENST00000303531 | + | 1 | 17 | 36_86 | 68 | 674 | Zinc finger | Phorbol-ester/DAG-type 1 |
| Tgene | PRKCB | chr16:28986878 | chr16:23999829 | ENST00000321728 | + | 1 | 17 | 36_86 | 68 | 672 | Zinc finger | Phorbol-ester/DAG-type 1 |
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FusionGeneSequence for SPNS1_PRKCB |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SPNS1_ENST00000565975_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_751aa MTGFKQHGGCRGAAPGLSDSKCSGLLPRVGSSVGPERGRARPPGTMAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQE GLQRITGLSPGRSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSK HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGL SDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQE EGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVK ILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKG IIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQ SIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVEL >In-frame_SPNS1_ENST00000565975_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_753aa MTGFKQHGGCRGAAPGLSDSKCSGLLPRVGSSVGPERGRARPPGTMAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQE GLQRITGLSPGRSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFFNIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSK HKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGL SDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQE EGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVK ILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKG IIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQ SIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLT >In-frame_SPNS1_ENST00000311008_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_706aa MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFF NIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMN VPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK DRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVS KFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRL YFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPD YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKE >In-frame_SPNS1_ENST00000311008_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_708aa MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFF NIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMN VPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK DRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVS KFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRL YFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPD YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKE >In-frame_SPNS1_ENST00000323081_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_633aa MDRFTVAGVLPDIEQFFNIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQG MKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSL NPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAK ISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKH PGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVI >In-frame_SPNS1_ENST00000323081_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_635aa MDRFTVAGVLPDIEQFFNIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQG MKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSL NPEWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAK ISQGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGK PPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCK ENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKH PGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLKP >In-frame_SPNS1_ENST00000334536_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_706aa MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFF NIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMN VPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK DRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVS KFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRL YFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPD YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKE >In-frame_SPNS1_ENST00000334536_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_708aa MAGSDTAPFLSQADDPDDGPVPGTPGLPGSTGNPKSEEPEVPDQEGLQRITGLSPGRSALIVAVLCYINLLNYMDRFTVAGVLPDIEQFF NIGDSSSGLIQTVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMN VPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDK DRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVS KFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRL YFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPD YIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SPNS1_ENST00000565975_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_2253nt ATGACCGGCTTTAAGCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGGTGGGA TCGTCGGTGGGACCGGAGCGCGGGCGGGCGCGGCCCCCCGGGACCATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGAC CCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCCACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAG GGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTCATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGAC CGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGC TTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAA CACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAA TGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGC ATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTG TCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCT GAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGC AGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAG GAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGT CAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGAT TTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAG ATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCC TTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCAC ATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGC ATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAAC ATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCC GTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAA TCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGC AAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAA GAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGACACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTG ACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTTCTCTTATACTAACCCAGAGTTTGTCATTAATGTG >In-frame_SPNS1_ENST00000565975_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_2259nt ATGACCGGCTTTAAGCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGGTGGGA TCGTCGGTGGGACCGGAGCGCGGGCGGGCGCGGCCCCCCGGGACCATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGAC CCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCCACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAG GGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTCATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGAC CGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGC TTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAA CACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAA TGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGC ATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTG TCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCT GAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGC AGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAG GAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGT CAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGAT TTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAG ATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCC TTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCAC ATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGC ATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAAC ATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCC GTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAA TCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGC AAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAA GAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCTGAAAACTTCGACCGATTTTTCACCCGCCATCCACCAGTCCTAACA CCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTCGAAGGATTTTCCTTTGTTAACTCTGAATTTTTAAAACCCGAAGTC >In-frame_SPNS1_ENST00000311008_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_2118nt ATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCC ACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTC ATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTC AACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGC CCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGAC CACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAAT GTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTC GTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGT GAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAA GACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTT CAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAG GCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCC AAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTC ATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGC ACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTG TACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTAC GCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCT GAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGAC TACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCT GGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAG GAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAG CATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGAC ACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAA >In-frame_SPNS1_ENST00000311008_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_2124nt ATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCC ACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTC ATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTC AACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGC CCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGAC CACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAAT GTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTC GTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGT GAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAA GACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTT CAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAG GCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCC AAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTC ATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGC ACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTG TACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTAC GCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCT GAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGAC TACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCT GGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAG GAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAG CATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCT GAAAACTTCGACCGATTTTTCACCCGCCATCCACCAGTCCTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTC >In-frame_SPNS1_ENST00000323081_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_1899nt ATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTT TGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGC AGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGG ATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGC GGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAAT GGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTC AACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTG ACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGC CAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAG ATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTG ACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCT GTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAG CCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATG TATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGT AAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAG GAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGG AAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTC TTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACAC CCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAA CGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGACACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTG GAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTTCTCTTATACTAACCCAGAGTTTGTCATT >In-frame_SPNS1_ENST00000323081_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_1905nt ATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTT TGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGC AGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGG ATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGC GGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAAT GGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTC AACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTG ACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGC CAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAG ATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTG ACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCT GTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAG CCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATG TATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGT AAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAG GAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGG AAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTC TTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACAC CCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAA CGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCTGAAAACTTCGACCGATTTTTCACCCGCCATCCACCAGTC CTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTCGAAGGATTTTCCTTTGTTAACTCTGAATTTTTAAAACCC >In-frame_SPNS1_ENST00000334536_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_2118nt ATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCC ACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTC ATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTC AACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGC CCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGAC CACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAAT GTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTC GTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGT GAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAA GACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTT CAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAG GCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCC AAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTC ATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGC ACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTG TACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTAC GCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCT GAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGAC TACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCT GGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAG GAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAG CATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGAC ACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAA >In-frame_SPNS1_ENST00000334536_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_2124nt ATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCC ACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTC ATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTC AACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGC CCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGAC CACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAAT GTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTC GTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGT GAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAA GACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTT CAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAG GCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCC AAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTC ATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGC ACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTG TACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTAC GCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCT GAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGAC TACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCT GGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAG GAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAG CATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCT GAAAACTTCGACCGATTTTTCACCCGCCATCCACCAGTCCTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SPNS1_ENST00000565975_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_2759nt CGCGTCACATGACCGGCTTTAAGCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCC GGGTGGGATCGTCGGTGGGACCGGAGCGCGGGCGGGCGCGGCCCCCCGGGACCATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGG CGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCCACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGG ACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTCATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACT ACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCG TTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCC GCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGG GGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCC GCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCA ATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCC TCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATT TGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGA GCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCA AGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAAC TGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATG CTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGA AGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCA TGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGA GTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTA AGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATG GGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAAC TCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAAC ACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTG AACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGACACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTG TGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTTCTCTTATACTAACCCAGAGTTTGTCA TTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCAAGCGTATGTATCAATTCTAGTCTTCCAGGAT TCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTTGTATGTGTAGCTTGCTAGTTTGTTTTCTACA TTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCAAACTTCCAGAAACTCATCAAATGAACAGACA ATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCAGAAGCTGATGTTCCTGGTAAAAGTTTTTACA GTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGAGTAAGCTTTGCAGTTACTGTGAACTATTGTC >In-frame_SPNS1_ENST00000565975_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_8062nt CGCGTCACATGACCGGCTTTAAGCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCC GGGTGGGATCGTCGGTGGGACCGGAGCGCGGGCGGGCGCGGCCCCCCGGGACCATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGG CGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCCACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGG ACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTCATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACT ACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCG TTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCC GCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGG GGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCC GCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCA ATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCC TCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATT TGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGA GCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCA AGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAAC TGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATG CTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGA AGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCA TGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGA GTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTA AGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATG GGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAAC TCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAAC ACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTG AACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCTGAAAACTTCGACCGATTTTTCACCCGCCATCCACCAG TCCTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTCGAAGGATTTTCCTTTGTTAACTCTGAATTTTTAAAAC CCGAAGTCAAGAGCTAAGTAGATGTGTAGATCTCCGTCCTTCATTTCTGTCATTCAAGCTCAACGGCTATTGTGGTGACATTTTTATGTT TTTCATTGCCAAGTTGCATCCATGTTTGATTTTCTGATGAGACTAGAGTGACAGTGTTTCAGAACCCAAATGTCCTCAGGTAGTTTGGAG CATCTCTATGAGATGGGATTATGCAGATGGCCTATGGAAAATGCAGCTGCATAATTAACACATTATCAAAGTCCTCTTACAATTTATTTT CCGCAGCATGTCAGCTAAGTAGACCCAATGGGGAGAGAAAATGCCTGCTTTCTTTCCCTCTTTTTCTGCACTGCCATATTCACCCCCAAC CATCCAATCTGTGGATAATTGGATGTTAGCGGTACTCTTCCACTTCCGGGCCTGGAGCTTGGCTTGTATCCAAGTGTATGGTTGCTTTGC CTAAGAGGAATCCCTCTATTTCACCTGTTCTGGAGGCACCAGACCTTGAAAAGAACATGCTCAAAATAAAATGTTATCTGTTATTTTTGT AAACTCAAAGTTAAGATGATCAAAGTTCTAAAATTCCAAGAATGTGCTTTTAGACGGTCTCAATCTAAAAGCACTTCAAGGGGTCAAAGG GCAACCAGCTTGGGTGCTACCTCAGTGTTGTAGTTTCTGATACTTTATGTCTTTGCTCACCCTCATCCCCAAACTACTTGAAAAGGGCAT TTGGCACCACTCTCTGAAACAACACAGTCACTCTAGCAAGGCCCCCAAAGGGCCCTGGTTTTACATTACATTTCAAACTTTATTTGCTTT GGGGTTTTGTTTCTGTTGTTGTTCAAATGCAAAAAAAAGAAAAAAAAAGAAAAAAAAAGGTGACTCACATTGTTACACATGCTTTAAAAT ATGTATTCAAATGTTATTAACCACAATGACGACCTGCTTTGATTTAACCAAGAAGACGGCTGCGGAGCCTAGCAGACTCAGGCCTGTGGG AATGGGATTTGTTACAAATCTAGGTTTGTTACTGGCTTCAGAAAGCTAATTAAGTGCTCTGAAAAAGACACCGTTTCTTGAAACAAAGAT GGTTGTATTCCTCACTTTGATGTTGTTTTGCAAGATGTTTGTGGAAATGTTCATTTGTATCTGGATCTCTGTTATGTGCCATTTTTCTTC TAGCATCGAGATACAATAAAAAAAAAAAAAAAGAAAAGAAGAAGAAATACTATTTCAAGGAAAACTGCTCTTTTTGAGAAACGTGGACCT AAACTACAAAGTGGGAACTGAGGAGGGAACTCAGGAGAAAGGAACTAACTGCGGAGCTTTAATCTTGGCCCCAGTGTTCAGCCACTCGGA GGGGCGGGGGCTGTGGCCCATTCAGGGGCTGCTGGTGGGCTGTAGTGGGGTGGGATGACCTGGCCAGAGCCAACGAGGATACTGGAGCCC AAAGTCAAGTTTAGAGACCAGCTGGGAACGTGAATGGGGCTCTTGATTTTCTTATCAAAATCACCACTCCTCCCAGCTTGGACTAAATAT TCTTTCTAGCAAGCAGCTTTGTGAGCTCCCTGAAGCCCAAGGAAACCCTTCGGTGGGAGAAATTTCATTTCTGTCTGAGAGGATTAAGGC AGCAGGTGACTCCCCCTCCTCGCCTGCCGTGTCCTGCTATTCTCAGGCAGCTCTAAGGAGAATTCTTATCACAGTTCAAGTGATTTCCAG AAGTTCCAGGGCTTCTGAGAGACCATCAAGGGAACTTTAACAACTTGACAAATGTCCTTGAAGTAAGATGCCTCATCTTTAGGGAAAAAT GGGGTTTGGATTTCTGCTTAGGCAAAGTCTCCTGCAGTTCATCCTTCTCTGTCCTCTTCTTGCTTCAGGCTTGGGGACCGTCCCTGCTGT CCCCACTGTGGTGGCAATCAGGACCTAAGGTGAAGCAAACTTGAAGTTCTATCTGACAAGTTTAGGCAGTAAGAGAAGGAGGGAAATCGG AGCAAAGCTCCCTCACTTTATTGTTGAGAAACTGGCATCTGGAAAGAGGAAGGAATTTGCCCAAAGTCAGTCAGCTGGGATAAAAACCTG GGTGTCCTGTCCAGAAAGTGCAGGGTGCTTTCTGCTCTGTAGCAAGGCAGCAGACATCTCTGAGCCAGGCCCACCAACAGGCCCTTATCT GGTGGTTGGATCATGATCCCATTTTGCTTGGACATGCTCTCAGGAAGATAAAAACCATGGAGAAACACTAGGCCATTGACAAATGATCTG AGACAACTTTAGAAAACAATGTAGGATGAATGGAAAGAGAAAGAAAGGAAAGAAAGAAGAAAAAGAAAGAAGGAAAGAAAGAAAGAGAAA GGAAGGAAGGAAAGAAGGAAGGAAAAGAAGGAAGGAAGGAAGGAATATAGTGTTATAAATACTGCACTCAACATTTTCCAAATTCTTGCC ATTATTTTTCAAAAGTTTAATAGTTTGCAGAAATAGATACTCAAGCCAAAGTCTGTTTTAGAGAAACTTTCCATGGAAAGTCAGAATTTC TACCACTTCCTTTTCTATCCACATTTCCAGTGCAGAAGAAACTGAGAAACAGAGCTTTTTGAAGAGAGGACAGGGCCATAGCAACAAGGA CCTTCTTGGGGGATTAATGGGAGGTCAGTAGAATTAATAACCCTCCTTGGATGAGTGCTACTGTTTTCACATGGCTTCAGATGCTATCAA CCTCAAAGAAATGATCTCAACAGAGAAGCTTATTCTCTCCCAACTTCTACGGTAAAATCCAGGAGTATTTTCTCTGGGGATCTGCCCACA GGACAAAGTCCATAAAAGCAAGTCCTGTCTGGACCATGTGGTTATCTGAAGCATTAGCCATCACCAGCACAACAAACGGGGCAGGGCTTT CCAAGGTGGGGCTGGTCAGAAGGGAATCTTTGATAAGAGGCCCACAGGCAGGGAAAGCGAAATAGGGTTGATGAGACCAGGGGAGACCTA AAAAAAAGGCAGCTTTGTGTCTTCTAGCTCCAAATATACCTGCCTTTTAGCTCACACACTGTCCTGGAGTTCTCAGACCTTTAGGGGCCC TAACACAGTTCAGTTCATACAGGGGTTCAAAAGGGACAGTGGCCCATTTGGGAGACCTTTAGGATCAATGGGAATCAATTCCATTGTTTT GCCTCAGAGTAAAGTTTCTGGCTCGGGGACAATTATAAGTTGCAAAAAGGATAGAGGCATATCCCAAGTCTTCCTTCATTCCACAAATAA TTACAAACAACCTACTGTGTGCCAGGCACTATTCTTAGCACTGGAAATACACTAGTGAAGAAGCAGATGAGGACCCTGTTTATTGTTTCT CTCCAAGAAATTCTCCAAGAATATTGTTTCTTGGAGAGAAATAATAAATAAACAAGACAATTTCTGAAAGCAATAAGTGCAATCAAGATA ATTAAAGGATGCTAAAGTGTGACTTGTGGGGATTGGGAGAGAGATGCACAGACAATATTAAAGAGGAGGCATTCGAGCTTTGTTGTGAAC ACCGGAAGTAACATGCCGAGCGCCTGGGGGATGGAAACTCCTATAGCACCCCACAGGCTAACAGCAAGCAGGACAAGACAAAAAGGGCAG GTGGGACATGGTAGAGATGGACCCTACCCAGGAAACAGCTCCATCAGCATCTTAGCCTGCCCCACTCTAGCCACACATACCCACGTGTGC TCCTGAGTTCAGTGTGCCCACCTCACTCCCACACCCTCACATAGACTTGGCAAGAGTAAGGAGGGAACTCCATAGAGACATTTTACCTAT CTCAGGGGAGCAGCCACAAAGAAGCAAGTCTTGTAAAAGGTCTTTTGCAAAGGAGAGTGAACCCAGCAATGAGAGATCCTTAACAGCTAG TGCCCATTAGGGGGCTAAACCTAAAGCCTGGGTGGTGATGGCTCAAACGCTAATGAGTCAGTGAATCCTTACCGACCCCCTGGCCTTTAT AATCTGAGGCAACTTTGGCTGCAGCCCGGGAATGTGCAGGGCACTAGGGAATACAAGGCCTTCTTCCCTGGTTGTCTTGTAATAAAACAG CCATGGGGTTGTCCCTCCAGTCCGAGAGACTGTGATGAGGCCTACATAGCAGCGATGTGGTCAGGTAAAAATCAGGAACCCACTGAAATC TTGGGCAAGCCACCCTGCCTGCTTGTGCCTCGGTTCTCTCATATGTCATATATAGGAGGTGAGGACTCCAGCTCCACCTGCCCCAGGTGG GTGTGGTGATGATGAGGAAAGACAAGAGGCTTGCAAGGACCCTGAAGAGGTCGGAGCATCATACAGATTCCTTTATTAGCCCACATTCTG ATGTTCCCTGGTGAGACTTGCCCCAAGCAATTGCTAGTAAATGGGGGTTAATTTCTTCTCCACCTCCCTACTGAACAAAAAAAGAAATGC CAGACTTACTAGGAGAATCGAGTTGCTTTGAGTTTCTTTTGTTTTGTTTTGTTTTGTTTTGTTTTAAGGCTCCCCTTACACACCCTCCTT TAAGCTTTGGGTTTTCTCTCTTATAGTTTGTTGACACATGCTAAAAATGTCTTTGGAGAGAACTTCTGCCTGATAAACACCCAATTCTAG ACTGTGGGTGGATTTTCGAGCTGACGGTGGTCAATTCCTTTCATTAAGCAGTGATCTGATTTCTCCACATGGCCATTCTGCCTTCTTGGG GGCAGAGTAGATGGGCAGCAGTTCACCTTTTCAGAGAAAGAGGTCTTCTAGCCACCTGGGCTGCTACTGAATGGTTTTCTCCAGGACGCT CTACCTAATGATTATTTCTATAACATTAAGCATGGTAATAAGTAGCTTCCAATTCAATTCATCCTAAAGCCAAAGAAAATACAGCAACAC ACACACACACACACACACACACACACACACACACACACACACACCACTTTATGGCAATTCTTAACTGACATTCAATGACTTACTTCTTTT CTTAGAAAATTTCCACCACATTTCTATCCCCAAGCCAACATACAATGTGAAATGAAAGCCAGTGCGTGGAGTGCAGCTGCTAAAAATTTT CAGCACAGGGCTCTTTCTGACTCTGCTCATGAGATGGTATCAGCCACCCAATGACTGGCGTATCTTGGTCCTGTGTCTTTCTTCTTACGC TGTGTTAATGTGTTTACTTTCCATTTGGCAGAGAGACAAGAGAGACACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACT GACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTTCTCTTATACTAACCCAGAGTTTGTCATTAATGT GTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCAAGCGTATGTATCAATTCTAGTCTTCCAGGATTCACGGT GCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTTGTATGTGTAGCTTGCTAGTTTGTTTTCTACATTTGAAA ATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCAAACTTCCAGAAACTCATCAAATGAACAGACAATGTCAA AACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCAGAAGCTGATGTTCCTGGTAAAAGTTTTTACAGTTATTC TATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGAGTAAGCTTTGCAGTTACTGTGAACTATTGTCTCTTGGA >In-frame_SPNS1_ENST00000311008_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_2993nt GTCACATGACCGGCTTTAAGCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGG TGAGGGGTGGCCTCCGCGTGGGATCGTGCCCTCTTCAGCCCGCTCCTGTCCCCGACATCACGTGTATTCCGCACGTCCCCTCCGCGCTGT GTGTCTACTGAGACGGGGAGGCGTGACAGGGCCCGGGTCCCTTCTCAGTGGTGCTCTGTGCTTCAGGGCAAGCTCCCCGTCTCCGGGCGC ACTTCCCTCGCCTGTGTTCGGTCCATCCTCCTTTCTCCAGCCTCCTCCCCTCGCAGGTGGGATCGTCGGTGGGACCGGAGCGCGGGCGGG CGCGGCCCCCCGGGACCATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCC CGGGGTTGCCAGGGTCCACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTC CCGGCCGTTCGGCTCTCATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCG ACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAAT TTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCA GCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACA AGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGG ACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGA TTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGC TGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCT TTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGC CACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGA CGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAG GCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAG ATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCC AGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGC CCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACA ACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACAT TCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGC TGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATC CCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCG AACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAG CTAGAGACAAGAGAGACACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGA ACTTGGACCAAAATGAATTTGCTGGCTTCTCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGC CTGGGGTGTAAGACTTCAAGCCAAGCGTATGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAG CTTGTCTTAGAGGGCTTTTCTTTGTATGTGTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCC AATTATAGAGGTACAATTTTCCAAACTTCCAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTC AGTATTTGTAATTTTTCAAGTCAGAAGCTGATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATG AGCGATATTTTTAAAAATTGTGAGTAAGCTTTGCAGTTACTGTGAACTATTGTCTCTTGGAGGAAGTTTTTTGTTTAAGAATTGATATGA >In-frame_SPNS1_ENST00000311008_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_8296nt GTCACATGACCGGCTTTAAGCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGG TGAGGGGTGGCCTCCGCGTGGGATCGTGCCCTCTTCAGCCCGCTCCTGTCCCCGACATCACGTGTATTCCGCACGTCCCCTCCGCGCTGT GTGTCTACTGAGACGGGGAGGCGTGACAGGGCCCGGGTCCCTTCTCAGTGGTGCTCTGTGCTTCAGGGCAAGCTCCCCGTCTCCGGGCGC ACTTCCCTCGCCTGTGTTCGGTCCATCCTCCTTTCTCCAGCCTCCTCCCCTCGCAGGTGGGATCGTCGGTGGGACCGGAGCGCGGGCGGG CGCGGCCCCCCGGGACCATGGCCGGGTCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCC CGGGGTTGCCAGGGTCCACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTC CCGGCCGTTCGGCTCTCATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCG ACATCGAGCAGTTCTTCAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAAT TTGTCACATTCTCCTGCCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCA GCCCCACGTTTTGTGACCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACA AGCGCTGCGTGATGAATGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGG ACGTCCTCATTGTCCTCGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGA TTCCCGATCCCAAAAGTGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGC TGAAAGAATCGGACAAAGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCT TTGGGATTTCTGAACTTCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGC CACCAGAAGGAAGTGAGGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGA CGACCAACACTGTCTCCAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAG GCAGCTTTGGCAAGGTCATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAG ATGATGACGTGGAGTGCACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCC AGACCATGGACCGCCTGTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGC CCCATGCTGTATTTTACGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACA ACGTGATGCTCGATTCTGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACAT TCTGTGGCACTCCAGACTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGC TGTATGAAATGTTGGCTGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATC CCAAGTCTATGTCCAAGGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCG AACGTGATATCAAAGAGCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAG CTTGTGGGCGAAATGCTGAAAACTTCGACCGATTTTTCACCCGCCATCCACCAGTCCTAACACCTCCCGACCAGGAAGTCATCAGGAATA TTGACCAATCAGAATTCGAAGGATTTTCCTTTGTTAACTCTGAATTTTTAAAACCCGAAGTCAAGAGCTAAGTAGATGTGTAGATCTCCG TCCTTCATTTCTGTCATTCAAGCTCAACGGCTATTGTGGTGACATTTTTATGTTTTTCATTGCCAAGTTGCATCCATGTTTGATTTTCTG ATGAGACTAGAGTGACAGTGTTTCAGAACCCAAATGTCCTCAGGTAGTTTGGAGCATCTCTATGAGATGGGATTATGCAGATGGCCTATG GAAAATGCAGCTGCATAATTAACACATTATCAAAGTCCTCTTACAATTTATTTTCCGCAGCATGTCAGCTAAGTAGACCCAATGGGGAGA GAAAATGCCTGCTTTCTTTCCCTCTTTTTCTGCACTGCCATATTCACCCCCAACCATCCAATCTGTGGATAATTGGATGTTAGCGGTACT CTTCCACTTCCGGGCCTGGAGCTTGGCTTGTATCCAAGTGTATGGTTGCTTTGCCTAAGAGGAATCCCTCTATTTCACCTGTTCTGGAGG CACCAGACCTTGAAAAGAACATGCTCAAAATAAAATGTTATCTGTTATTTTTGTAAACTCAAAGTTAAGATGATCAAAGTTCTAAAATTC CAAGAATGTGCTTTTAGACGGTCTCAATCTAAAAGCACTTCAAGGGGTCAAAGGGCAACCAGCTTGGGTGCTACCTCAGTGTTGTAGTTT CTGATACTTTATGTCTTTGCTCACCCTCATCCCCAAACTACTTGAAAAGGGCATTTGGCACCACTCTCTGAAACAACACAGTCACTCTAG CAAGGCCCCCAAAGGGCCCTGGTTTTACATTACATTTCAAACTTTATTTGCTTTGGGGTTTTGTTTCTGTTGTTGTTCAAATGCAAAAAA AAGAAAAAAAAAGAAAAAAAAAGGTGACTCACATTGTTACACATGCTTTAAAATATGTATTCAAATGTTATTAACCACAATGACGACCTG CTTTGATTTAACCAAGAAGACGGCTGCGGAGCCTAGCAGACTCAGGCCTGTGGGAATGGGATTTGTTACAAATCTAGGTTTGTTACTGGC TTCAGAAAGCTAATTAAGTGCTCTGAAAAAGACACCGTTTCTTGAAACAAAGATGGTTGTATTCCTCACTTTGATGTTGTTTTGCAAGAT GTTTGTGGAAATGTTCATTTGTATCTGGATCTCTGTTATGTGCCATTTTTCTTCTAGCATCGAGATACAATAAAAAAAAAAAAAAAGAAA AGAAGAAGAAATACTATTTCAAGGAAAACTGCTCTTTTTGAGAAACGTGGACCTAAACTACAAAGTGGGAACTGAGGAGGGAACTCAGGA GAAAGGAACTAACTGCGGAGCTTTAATCTTGGCCCCAGTGTTCAGCCACTCGGAGGGGCGGGGGCTGTGGCCCATTCAGGGGCTGCTGGT GGGCTGTAGTGGGGTGGGATGACCTGGCCAGAGCCAACGAGGATACTGGAGCCCAAAGTCAAGTTTAGAGACCAGCTGGGAACGTGAATG GGGCTCTTGATTTTCTTATCAAAATCACCACTCCTCCCAGCTTGGACTAAATATTCTTTCTAGCAAGCAGCTTTGTGAGCTCCCTGAAGC CCAAGGAAACCCTTCGGTGGGAGAAATTTCATTTCTGTCTGAGAGGATTAAGGCAGCAGGTGACTCCCCCTCCTCGCCTGCCGTGTCCTG CTATTCTCAGGCAGCTCTAAGGAGAATTCTTATCACAGTTCAAGTGATTTCCAGAAGTTCCAGGGCTTCTGAGAGACCATCAAGGGAACT TTAACAACTTGACAAATGTCCTTGAAGTAAGATGCCTCATCTTTAGGGAAAAATGGGGTTTGGATTTCTGCTTAGGCAAAGTCTCCTGCA GTTCATCCTTCTCTGTCCTCTTCTTGCTTCAGGCTTGGGGACCGTCCCTGCTGTCCCCACTGTGGTGGCAATCAGGACCTAAGGTGAAGC AAACTTGAAGTTCTATCTGACAAGTTTAGGCAGTAAGAGAAGGAGGGAAATCGGAGCAAAGCTCCCTCACTTTATTGTTGAGAAACTGGC ATCTGGAAAGAGGAAGGAATTTGCCCAAAGTCAGTCAGCTGGGATAAAAACCTGGGTGTCCTGTCCAGAAAGTGCAGGGTGCTTTCTGCT CTGTAGCAAGGCAGCAGACATCTCTGAGCCAGGCCCACCAACAGGCCCTTATCTGGTGGTTGGATCATGATCCCATTTTGCTTGGACATG CTCTCAGGAAGATAAAAACCATGGAGAAACACTAGGCCATTGACAAATGATCTGAGACAACTTTAGAAAACAATGTAGGATGAATGGAAA GAGAAAGAAAGGAAAGAAAGAAGAAAAAGAAAGAAGGAAAGAAAGAAAGAGAAAGGAAGGAAGGAAAGAAGGAAGGAAAAGAAGGAAGGA AGGAAGGAATATAGTGTTATAAATACTGCACTCAACATTTTCCAAATTCTTGCCATTATTTTTCAAAAGTTTAATAGTTTGCAGAAATAG ATACTCAAGCCAAAGTCTGTTTTAGAGAAACTTTCCATGGAAAGTCAGAATTTCTACCACTTCCTTTTCTATCCACATTTCCAGTGCAGA AGAAACTGAGAAACAGAGCTTTTTGAAGAGAGGACAGGGCCATAGCAACAAGGACCTTCTTGGGGGATTAATGGGAGGTCAGTAGAATTA ATAACCCTCCTTGGATGAGTGCTACTGTTTTCACATGGCTTCAGATGCTATCAACCTCAAAGAAATGATCTCAACAGAGAAGCTTATTCT CTCCCAACTTCTACGGTAAAATCCAGGAGTATTTTCTCTGGGGATCTGCCCACAGGACAAAGTCCATAAAAGCAAGTCCTGTCTGGACCA TGTGGTTATCTGAAGCATTAGCCATCACCAGCACAACAAACGGGGCAGGGCTTTCCAAGGTGGGGCTGGTCAGAAGGGAATCTTTGATAA GAGGCCCACAGGCAGGGAAAGCGAAATAGGGTTGATGAGACCAGGGGAGACCTAAAAAAAAGGCAGCTTTGTGTCTTCTAGCTCCAAATA TACCTGCCTTTTAGCTCACACACTGTCCTGGAGTTCTCAGACCTTTAGGGGCCCTAACACAGTTCAGTTCATACAGGGGTTCAAAAGGGA CAGTGGCCCATTTGGGAGACCTTTAGGATCAATGGGAATCAATTCCATTGTTTTGCCTCAGAGTAAAGTTTCTGGCTCGGGGACAATTAT AAGTTGCAAAAAGGATAGAGGCATATCCCAAGTCTTCCTTCATTCCACAAATAATTACAAACAACCTACTGTGTGCCAGGCACTATTCTT AGCACTGGAAATACACTAGTGAAGAAGCAGATGAGGACCCTGTTTATTGTTTCTCTCCAAGAAATTCTCCAAGAATATTGTTTCTTGGAG AGAAATAATAAATAAACAAGACAATTTCTGAAAGCAATAAGTGCAATCAAGATAATTAAAGGATGCTAAAGTGTGACTTGTGGGGATTGG GAGAGAGATGCACAGACAATATTAAAGAGGAGGCATTCGAGCTTTGTTGTGAACACCGGAAGTAACATGCCGAGCGCCTGGGGGATGGAA ACTCCTATAGCACCCCACAGGCTAACAGCAAGCAGGACAAGACAAAAAGGGCAGGTGGGACATGGTAGAGATGGACCCTACCCAGGAAAC AGCTCCATCAGCATCTTAGCCTGCCCCACTCTAGCCACACATACCCACGTGTGCTCCTGAGTTCAGTGTGCCCACCTCACTCCCACACCC TCACATAGACTTGGCAAGAGTAAGGAGGGAACTCCATAGAGACATTTTACCTATCTCAGGGGAGCAGCCACAAAGAAGCAAGTCTTGTAA AAGGTCTTTTGCAAAGGAGAGTGAACCCAGCAATGAGAGATCCTTAACAGCTAGTGCCCATTAGGGGGCTAAACCTAAAGCCTGGGTGGT GATGGCTCAAACGCTAATGAGTCAGTGAATCCTTACCGACCCCCTGGCCTTTATAATCTGAGGCAACTTTGGCTGCAGCCCGGGAATGTG CAGGGCACTAGGGAATACAAGGCCTTCTTCCCTGGTTGTCTTGTAATAAAACAGCCATGGGGTTGTCCCTCCAGTCCGAGAGACTGTGAT GAGGCCTACATAGCAGCGATGTGGTCAGGTAAAAATCAGGAACCCACTGAAATCTTGGGCAAGCCACCCTGCCTGCTTGTGCCTCGGTTC TCTCATATGTCATATATAGGAGGTGAGGACTCCAGCTCCACCTGCCCCAGGTGGGTGTGGTGATGATGAGGAAAGACAAGAGGCTTGCAA GGACCCTGAAGAGGTCGGAGCATCATACAGATTCCTTTATTAGCCCACATTCTGATGTTCCCTGGTGAGACTTGCCCCAAGCAATTGCTA GTAAATGGGGGTTAATTTCTTCTCCACCTCCCTACTGAACAAAAAAAGAAATGCCAGACTTACTAGGAGAATCGAGTTGCTTTGAGTTTC TTTTGTTTTGTTTTGTTTTGTTTTGTTTTAAGGCTCCCCTTACACACCCTCCTTTAAGCTTTGGGTTTTCTCTCTTATAGTTTGTTGACA CATGCTAAAAATGTCTTTGGAGAGAACTTCTGCCTGATAAACACCCAATTCTAGACTGTGGGTGGATTTTCGAGCTGACGGTGGTCAATT CCTTTCATTAAGCAGTGATCTGATTTCTCCACATGGCCATTCTGCCTTCTTGGGGGCAGAGTAGATGGGCAGCAGTTCACCTTTTCAGAG AAAGAGGTCTTCTAGCCACCTGGGCTGCTACTGAATGGTTTTCTCCAGGACGCTCTACCTAATGATTATTTCTATAACATTAAGCATGGT AATAAGTAGCTTCCAATTCAATTCATCCTAAAGCCAAAGAAAATACAGCAACACACACACACACACACACACACACACACACACACACAC ACACACACCACTTTATGGCAATTCTTAACTGACATTCAATGACTTACTTCTTTTCTTAGAAAATTTCCACCACATTTCTATCCCCAAGCC AACATACAATGTGAAATGAAAGCCAGTGCGTGGAGTGCAGCTGCTAAAAATTTTCAGCACAGGGCTCTTTCTGACTCTGCTCATGAGATG GTATCAGCCACCCAATGACTGGCGTATCTTGGTCCTGTGTCTTTCTTCTTACGCTGTGTTAATGTGTTTACTTTCCATTTGGCAGAGAGA CAAGAGAGACACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGA CCAAAATGAATTTGCTGGCTTCTCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGT GTAAGACTTCAAGCCAAGCGTATGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCT TAGAGGGCTTTTCTTTGTATGTGTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATA GAGGTACAATTTTCCAAACTTCCAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTT GTAATTTTTCAAGTCAGAAGCTGATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATA TTTTTAAAAATTGTGAGTAAGCTTTGCAGTTACTGTGAACTATTGTCTCTTGGAGGAAGTTTTTTGTTTAAGAATTGATATGATTAAACT >In-frame_SPNS1_ENST00000323081_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_2887nt GCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGGTGAGGGGTGGCCTCCGCGT GGGATCGTGCCCTCTTCAGCCCGCTCCTGTCCCCGACATCACGTGTATTCCGCACGTCCCCTCCGCGCTGTGTGTCTACTGAGACGGGGA GGCGTGACAGGGCCCGGGTCCCTTCTCAGTGGTGCTCTGTGCTTCAGGGCAAGCTCCCCGTCTCCGGGCGCACTTCCCTCGCCTGTGTTC GGTCCATCCTCCTTTCTCCAGCCTCCTCCCCTCGCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTC CACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCT CATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTT CAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTG CCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGA CCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAA TGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCT CGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAG TGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAA AGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACT TCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGA GGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTC CAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGT CATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTG CACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCT GTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTA CGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTC TGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGA CTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGC TGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAA GGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGA GCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGA CACCTCCAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGA ATTTGCTGGCTTCTCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTT CAAGCCAAGCGTATGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCT TTTCTTTGTATGTGTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAA TTTTCCAAACTTCCAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTT CAAGTCAGAAGCTGATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAA ATTGTGAGTAAGCTTTGCAGTTACTGTGAACTATTGTCTCTTGGAGGAAGTTTTTTGTTTAAGAATTGATATGATTAAACTGAATTAATA >In-frame_SPNS1_ENST00000323081_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_8190nt GCAACATGGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGGTGAGGGGTGGCCTCCGCGT GGGATCGTGCCCTCTTCAGCCCGCTCCTGTCCCCGACATCACGTGTATTCCGCACGTCCCCTCCGCGCTGTGTGTCTACTGAGACGGGGA GGCGTGACAGGGCCCGGGTCCCTTCTCAGTGGTGCTCTGTGCTTCAGGGCAAGCTCCCCGTCTCCGGGCGCACTTCCCTCGCCTGTGTTC GGTCCATCCTCCTTTCTCCAGCCTCCTCCCCTCGCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTC CACGGGGAACCCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCT CATAGTGGCGGTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTT CAACATCGGGGACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTG CCCTGGCGCTGACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGA CCACTGTGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAA TGTTCCCAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCT CGTAAGAGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAG TGAGAGCAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAA AGACAGAAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACT TCAGAAAGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGA GGCCAATGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTC CAAATTTGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGT CATGCTTTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTG CACTATGGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCT GTACTTTGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTA CGCTGCAGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTC TGAGGGACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGA CTACATCGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGC TGGGCAGGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAA GGAAGCTGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGA GCATGCATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGC TGAAAACTTCGACCGATTTTTCACCCGCCATCCACCAGTCCTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATT CGAAGGATTTTCCTTTGTTAACTCTGAATTTTTAAAACCCGAAGTCAAGAGCTAAGTAGATGTGTAGATCTCCGTCCTTCATTTCTGTCA TTCAAGCTCAACGGCTATTGTGGTGACATTTTTATGTTTTTCATTGCCAAGTTGCATCCATGTTTGATTTTCTGATGAGACTAGAGTGAC AGTGTTTCAGAACCCAAATGTCCTCAGGTAGTTTGGAGCATCTCTATGAGATGGGATTATGCAGATGGCCTATGGAAAATGCAGCTGCAT AATTAACACATTATCAAAGTCCTCTTACAATTTATTTTCCGCAGCATGTCAGCTAAGTAGACCCAATGGGGAGAGAAAATGCCTGCTTTC TTTCCCTCTTTTTCTGCACTGCCATATTCACCCCCAACCATCCAATCTGTGGATAATTGGATGTTAGCGGTACTCTTCCACTTCCGGGCC TGGAGCTTGGCTTGTATCCAAGTGTATGGTTGCTTTGCCTAAGAGGAATCCCTCTATTTCACCTGTTCTGGAGGCACCAGACCTTGAAAA GAACATGCTCAAAATAAAATGTTATCTGTTATTTTTGTAAACTCAAAGTTAAGATGATCAAAGTTCTAAAATTCCAAGAATGTGCTTTTA GACGGTCTCAATCTAAAAGCACTTCAAGGGGTCAAAGGGCAACCAGCTTGGGTGCTACCTCAGTGTTGTAGTTTCTGATACTTTATGTCT TTGCTCACCCTCATCCCCAAACTACTTGAAAAGGGCATTTGGCACCACTCTCTGAAACAACACAGTCACTCTAGCAAGGCCCCCAAAGGG CCCTGGTTTTACATTACATTTCAAACTTTATTTGCTTTGGGGTTTTGTTTCTGTTGTTGTTCAAATGCAAAAAAAAGAAAAAAAAAGAAA AAAAAAGGTGACTCACATTGTTACACATGCTTTAAAATATGTATTCAAATGTTATTAACCACAATGACGACCTGCTTTGATTTAACCAAG AAGACGGCTGCGGAGCCTAGCAGACTCAGGCCTGTGGGAATGGGATTTGTTACAAATCTAGGTTTGTTACTGGCTTCAGAAAGCTAATTA AGTGCTCTGAAAAAGACACCGTTTCTTGAAACAAAGATGGTTGTATTCCTCACTTTGATGTTGTTTTGCAAGATGTTTGTGGAAATGTTC ATTTGTATCTGGATCTCTGTTATGTGCCATTTTTCTTCTAGCATCGAGATACAATAAAAAAAAAAAAAAAGAAAAGAAGAAGAAATACTA TTTCAAGGAAAACTGCTCTTTTTGAGAAACGTGGACCTAAACTACAAAGTGGGAACTGAGGAGGGAACTCAGGAGAAAGGAACTAACTGC GGAGCTTTAATCTTGGCCCCAGTGTTCAGCCACTCGGAGGGGCGGGGGCTGTGGCCCATTCAGGGGCTGCTGGTGGGCTGTAGTGGGGTG GGATGACCTGGCCAGAGCCAACGAGGATACTGGAGCCCAAAGTCAAGTTTAGAGACCAGCTGGGAACGTGAATGGGGCTCTTGATTTTCT TATCAAAATCACCACTCCTCCCAGCTTGGACTAAATATTCTTTCTAGCAAGCAGCTTTGTGAGCTCCCTGAAGCCCAAGGAAACCCTTCG GTGGGAGAAATTTCATTTCTGTCTGAGAGGATTAAGGCAGCAGGTGACTCCCCCTCCTCGCCTGCCGTGTCCTGCTATTCTCAGGCAGCT CTAAGGAGAATTCTTATCACAGTTCAAGTGATTTCCAGAAGTTCCAGGGCTTCTGAGAGACCATCAAGGGAACTTTAACAACTTGACAAA TGTCCTTGAAGTAAGATGCCTCATCTTTAGGGAAAAATGGGGTTTGGATTTCTGCTTAGGCAAAGTCTCCTGCAGTTCATCCTTCTCTGT CCTCTTCTTGCTTCAGGCTTGGGGACCGTCCCTGCTGTCCCCACTGTGGTGGCAATCAGGACCTAAGGTGAAGCAAACTTGAAGTTCTAT CTGACAAGTTTAGGCAGTAAGAGAAGGAGGGAAATCGGAGCAAAGCTCCCTCACTTTATTGTTGAGAAACTGGCATCTGGAAAGAGGAAG GAATTTGCCCAAAGTCAGTCAGCTGGGATAAAAACCTGGGTGTCCTGTCCAGAAAGTGCAGGGTGCTTTCTGCTCTGTAGCAAGGCAGCA GACATCTCTGAGCCAGGCCCACCAACAGGCCCTTATCTGGTGGTTGGATCATGATCCCATTTTGCTTGGACATGCTCTCAGGAAGATAAA AACCATGGAGAAACACTAGGCCATTGACAAATGATCTGAGACAACTTTAGAAAACAATGTAGGATGAATGGAAAGAGAAAGAAAGGAAAG AAAGAAGAAAAAGAAAGAAGGAAAGAAAGAAAGAGAAAGGAAGGAAGGAAAGAAGGAAGGAAAAGAAGGAAGGAAGGAAGGAATATAGTG TTATAAATACTGCACTCAACATTTTCCAAATTCTTGCCATTATTTTTCAAAAGTTTAATAGTTTGCAGAAATAGATACTCAAGCCAAAGT CTGTTTTAGAGAAACTTTCCATGGAAAGTCAGAATTTCTACCACTTCCTTTTCTATCCACATTTCCAGTGCAGAAGAAACTGAGAAACAG AGCTTTTTGAAGAGAGGACAGGGCCATAGCAACAAGGACCTTCTTGGGGGATTAATGGGAGGTCAGTAGAATTAATAACCCTCCTTGGAT GAGTGCTACTGTTTTCACATGGCTTCAGATGCTATCAACCTCAAAGAAATGATCTCAACAGAGAAGCTTATTCTCTCCCAACTTCTACGG TAAAATCCAGGAGTATTTTCTCTGGGGATCTGCCCACAGGACAAAGTCCATAAAAGCAAGTCCTGTCTGGACCATGTGGTTATCTGAAGC ATTAGCCATCACCAGCACAACAAACGGGGCAGGGCTTTCCAAGGTGGGGCTGGTCAGAAGGGAATCTTTGATAAGAGGCCCACAGGCAGG GAAAGCGAAATAGGGTTGATGAGACCAGGGGAGACCTAAAAAAAAGGCAGCTTTGTGTCTTCTAGCTCCAAATATACCTGCCTTTTAGCT CACACACTGTCCTGGAGTTCTCAGACCTTTAGGGGCCCTAACACAGTTCAGTTCATACAGGGGTTCAAAAGGGACAGTGGCCCATTTGGG AGACCTTTAGGATCAATGGGAATCAATTCCATTGTTTTGCCTCAGAGTAAAGTTTCTGGCTCGGGGACAATTATAAGTTGCAAAAAGGAT AGAGGCATATCCCAAGTCTTCCTTCATTCCACAAATAATTACAAACAACCTACTGTGTGCCAGGCACTATTCTTAGCACTGGAAATACAC TAGTGAAGAAGCAGATGAGGACCCTGTTTATTGTTTCTCTCCAAGAAATTCTCCAAGAATATTGTTTCTTGGAGAGAAATAATAAATAAA CAAGACAATTTCTGAAAGCAATAAGTGCAATCAAGATAATTAAAGGATGCTAAAGTGTGACTTGTGGGGATTGGGAGAGAGATGCACAGA CAATATTAAAGAGGAGGCATTCGAGCTTTGTTGTGAACACCGGAAGTAACATGCCGAGCGCCTGGGGGATGGAAACTCCTATAGCACCCC ACAGGCTAACAGCAAGCAGGACAAGACAAAAAGGGCAGGTGGGACATGGTAGAGATGGACCCTACCCAGGAAACAGCTCCATCAGCATCT TAGCCTGCCCCACTCTAGCCACACATACCCACGTGTGCTCCTGAGTTCAGTGTGCCCACCTCACTCCCACACCCTCACATAGACTTGGCA AGAGTAAGGAGGGAACTCCATAGAGACATTTTACCTATCTCAGGGGAGCAGCCACAAAGAAGCAAGTCTTGTAAAAGGTCTTTTGCAAAG GAGAGTGAACCCAGCAATGAGAGATCCTTAACAGCTAGTGCCCATTAGGGGGCTAAACCTAAAGCCTGGGTGGTGATGGCTCAAACGCTA ATGAGTCAGTGAATCCTTACCGACCCCCTGGCCTTTATAATCTGAGGCAACTTTGGCTGCAGCCCGGGAATGTGCAGGGCACTAGGGAAT ACAAGGCCTTCTTCCCTGGTTGTCTTGTAATAAAACAGCCATGGGGTTGTCCCTCCAGTCCGAGAGACTGTGATGAGGCCTACATAGCAG CGATGTGGTCAGGTAAAAATCAGGAACCCACTGAAATCTTGGGCAAGCCACCCTGCCTGCTTGTGCCTCGGTTCTCTCATATGTCATATA TAGGAGGTGAGGACTCCAGCTCCACCTGCCCCAGGTGGGTGTGGTGATGATGAGGAAAGACAAGAGGCTTGCAAGGACCCTGAAGAGGTC GGAGCATCATACAGATTCCTTTATTAGCCCACATTCTGATGTTCCCTGGTGAGACTTGCCCCAAGCAATTGCTAGTAAATGGGGGTTAAT TTCTTCTCCACCTCCCTACTGAACAAAAAAAGAAATGCCAGACTTACTAGGAGAATCGAGTTGCTTTGAGTTTCTTTTGTTTTGTTTTGT TTTGTTTTGTTTTAAGGCTCCCCTTACACACCCTCCTTTAAGCTTTGGGTTTTCTCTCTTATAGTTTGTTGACACATGCTAAAAATGTCT TTGGAGAGAACTTCTGCCTGATAAACACCCAATTCTAGACTGTGGGTGGATTTTCGAGCTGACGGTGGTCAATTCCTTTCATTAAGCAGT GATCTGATTTCTCCACATGGCCATTCTGCCTTCTTGGGGGCAGAGTAGATGGGCAGCAGTTCACCTTTTCAGAGAAAGAGGTCTTCTAGC CACCTGGGCTGCTACTGAATGGTTTTCTCCAGGACGCTCTACCTAATGATTATTTCTATAACATTAAGCATGGTAATAAGTAGCTTCCAA TTCAATTCATCCTAAAGCCAAAGAAAATACAGCAACACACACACACACACACACACACACACACACACACACACACACACACCACTTTAT GGCAATTCTTAACTGACATTCAATGACTTACTTCTTTTCTTAGAAAATTTCCACCACATTTCTATCCCCAAGCCAACATACAATGTGAAA TGAAAGCCAGTGCGTGGAGTGCAGCTGCTAAAAATTTTCAGCACAGGGCTCTTTCTGACTCTGCTCATGAGATGGTATCAGCCACCCAAT GACTGGCGTATCTTGGTCCTGTGTCTTTCTTCTTACGCTGTGTTAATGTGTTTACTTTCCATTTGGCAGAGAGACAAGAGAGACACCTCC AACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCT GGCTTCTCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCA AGCGTATGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTT GTATGTGTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCA AACTTCCAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCA GAAGCTGATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGA GTAAGCTTTGCAGTTACTGTGAACTATTGTCTCTTGGAGGAAGTTTTTTGTTTAAGAATTGATATGATTAAACTGAATTAATATATGCAA >In-frame_SPNS1_ENST00000334536_chr16_28986878_+_PRKCB_ENST00000321728_chr16_23999829_+_2967nt GGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGGTGAGGGGTGGCCTCCGCGTGGGATCG TGCCCTCTTCAGCCCGCTCCTGTCCCCGACATCACGTGTATTCCGCACGTCCCCTCCGCGCTGTGTGTCTACTGAGACGGGGAGGCGTGA CAGGGCCCGGGTCCCTTCTCAGTGGTGCTCTGTGCTTCAGGGCAAGCTCCCCGTCTCCGGGCGCACTTCCCTCGCCTGTGTTCGGTCCAT CCTCCTTTCTCCAGCCTCCTCCCCTCGCAGGTGGGATCGTCGGTGGGACCGGAGCGCGGGCGGGCGCGGCCCCCCGGGACCATGGCCGGG TCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCCACGGGGAAC CCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTCATAGTGGCG GTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGG GACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCT GACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGG TCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGC CTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGAT GCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAA CAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGA CTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCC AGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAA GAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGAC AACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCA GAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTG GAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTG ATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAA ATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACAC ATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCC CCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCA CCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTG GCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTT TTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGACACCTCCAAC TTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGC TTCTCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCAAGC GTATGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTTGTA TGTGTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCAAAC TTCCAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCAGAA GCTGATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGAGTA >In-frame_SPNS1_ENST00000334536_chr16_28986878_+_PRKCB_ENST00000303531_chr16_23999829_+_8270nt GGCGGCTGCCGTGGTGCAGCGCCCGGGCTGAGCGACAGCAAGTGCAGCGGGCTCCTACCCCGGGTGAGGGGTGGCCTCCGCGTGGGATCG TGCCCTCTTCAGCCCGCTCCTGTCCCCGACATCACGTGTATTCCGCACGTCCCCTCCGCGCTGTGTGTCTACTGAGACGGGGAGGCGTGA CAGGGCCCGGGTCCCTTCTCAGTGGTGCTCTGTGCTTCAGGGCAAGCTCCCCGTCTCCGGGCGCACTTCCCTCGCCTGTGTTCGGTCCAT CCTCCTTTCTCCAGCCTCCTCCCCTCGCAGGTGGGATCGTCGGTGGGACCGGAGCGCGGGCGGGCGCGGCCCCCCGGGACCATGGCCGGG TCCGACACCGCGCCCTTCCTCAGCCAGGCGGATGACCCGGACGACGGGCCAGTGCCTGGCACCCCGGGGTTGCCAGGGTCCACGGGGAAC CCGAAGTCCGAGGAGCCCGAGGTCCCGGACCAGGAGGGGCTGCAGCGCATCACCGGCCTGTCTCCCGGCCGTTCGGCTCTCATAGTGGCG GTGCTGTGCTACATCAATCTCCTGAACTACATGGACCGCTTCACCGTGGCTGGCGTCCTTCCCGACATCGAGCAGTTCTTCAACATCGGG GACAGTAGCTCTGGGCTCATCCAGACCGTTTGCTGCTTTGTGGTGCACAAGCGGTGCCATGAATTTGTCACATTCTCCTGCCCTGGCGCT GACAAGGGTCCAGCCTCCGATGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGG TCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGC CTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGAT GCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAA CAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGA CTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCC AGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAA GAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGAC AACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCA GAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTG GAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTG ATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAA ATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACAC ATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCC CCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCA CCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTG GCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTT TTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCTGAAAACTTC GACCGATTTTTCACCCGCCATCCACCAGTCCTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTCGAAGGATTT TCCTTTGTTAACTCTGAATTTTTAAAACCCGAAGTCAAGAGCTAAGTAGATGTGTAGATCTCCGTCCTTCATTTCTGTCATTCAAGCTCA ACGGCTATTGTGGTGACATTTTTATGTTTTTCATTGCCAAGTTGCATCCATGTTTGATTTTCTGATGAGACTAGAGTGACAGTGTTTCAG AACCCAAATGTCCTCAGGTAGTTTGGAGCATCTCTATGAGATGGGATTATGCAGATGGCCTATGGAAAATGCAGCTGCATAATTAACACA TTATCAAAGTCCTCTTACAATTTATTTTCCGCAGCATGTCAGCTAAGTAGACCCAATGGGGAGAGAAAATGCCTGCTTTCTTTCCCTCTT TTTCTGCACTGCCATATTCACCCCCAACCATCCAATCTGTGGATAATTGGATGTTAGCGGTACTCTTCCACTTCCGGGCCTGGAGCTTGG CTTGTATCCAAGTGTATGGTTGCTTTGCCTAAGAGGAATCCCTCTATTTCACCTGTTCTGGAGGCACCAGACCTTGAAAAGAACATGCTC AAAATAAAATGTTATCTGTTATTTTTGTAAACTCAAAGTTAAGATGATCAAAGTTCTAAAATTCCAAGAATGTGCTTTTAGACGGTCTCA ATCTAAAAGCACTTCAAGGGGTCAAAGGGCAACCAGCTTGGGTGCTACCTCAGTGTTGTAGTTTCTGATACTTTATGTCTTTGCTCACCC TCATCCCCAAACTACTTGAAAAGGGCATTTGGCACCACTCTCTGAAACAACACAGTCACTCTAGCAAGGCCCCCAAAGGGCCCTGGTTTT ACATTACATTTCAAACTTTATTTGCTTTGGGGTTTTGTTTCTGTTGTTGTTCAAATGCAAAAAAAAGAAAAAAAAAGAAAAAAAAAGGTG ACTCACATTGTTACACATGCTTTAAAATATGTATTCAAATGTTATTAACCACAATGACGACCTGCTTTGATTTAACCAAGAAGACGGCTG CGGAGCCTAGCAGACTCAGGCCTGTGGGAATGGGATTTGTTACAAATCTAGGTTTGTTACTGGCTTCAGAAAGCTAATTAAGTGCTCTGA AAAAGACACCGTTTCTTGAAACAAAGATGGTTGTATTCCTCACTTTGATGTTGTTTTGCAAGATGTTTGTGGAAATGTTCATTTGTATCT GGATCTCTGTTATGTGCCATTTTTCTTCTAGCATCGAGATACAATAAAAAAAAAAAAAAAGAAAAGAAGAAGAAATACTATTTCAAGGAA AACTGCTCTTTTTGAGAAACGTGGACCTAAACTACAAAGTGGGAACTGAGGAGGGAACTCAGGAGAAAGGAACTAACTGCGGAGCTTTAA TCTTGGCCCCAGTGTTCAGCCACTCGGAGGGGCGGGGGCTGTGGCCCATTCAGGGGCTGCTGGTGGGCTGTAGTGGGGTGGGATGACCTG GCCAGAGCCAACGAGGATACTGGAGCCCAAAGTCAAGTTTAGAGACCAGCTGGGAACGTGAATGGGGCTCTTGATTTTCTTATCAAAATC ACCACTCCTCCCAGCTTGGACTAAATATTCTTTCTAGCAAGCAGCTTTGTGAGCTCCCTGAAGCCCAAGGAAACCCTTCGGTGGGAGAAA TTTCATTTCTGTCTGAGAGGATTAAGGCAGCAGGTGACTCCCCCTCCTCGCCTGCCGTGTCCTGCTATTCTCAGGCAGCTCTAAGGAGAA TTCTTATCACAGTTCAAGTGATTTCCAGAAGTTCCAGGGCTTCTGAGAGACCATCAAGGGAACTTTAACAACTTGACAAATGTCCTTGAA GTAAGATGCCTCATCTTTAGGGAAAAATGGGGTTTGGATTTCTGCTTAGGCAAAGTCTCCTGCAGTTCATCCTTCTCTGTCCTCTTCTTG CTTCAGGCTTGGGGACCGTCCCTGCTGTCCCCACTGTGGTGGCAATCAGGACCTAAGGTGAAGCAAACTTGAAGTTCTATCTGACAAGTT TAGGCAGTAAGAGAAGGAGGGAAATCGGAGCAAAGCTCCCTCACTTTATTGTTGAGAAACTGGCATCTGGAAAGAGGAAGGAATTTGCCC AAAGTCAGTCAGCTGGGATAAAAACCTGGGTGTCCTGTCCAGAAAGTGCAGGGTGCTTTCTGCTCTGTAGCAAGGCAGCAGACATCTCTG AGCCAGGCCCACCAACAGGCCCTTATCTGGTGGTTGGATCATGATCCCATTTTGCTTGGACATGCTCTCAGGAAGATAAAAACCATGGAG AAACACTAGGCCATTGACAAATGATCTGAGACAACTTTAGAAAACAATGTAGGATGAATGGAAAGAGAAAGAAAGGAAAGAAAGAAGAAA AAGAAAGAAGGAAAGAAAGAAAGAGAAAGGAAGGAAGGAAAGAAGGAAGGAAAAGAAGGAAGGAAGGAAGGAATATAGTGTTATAAATAC TGCACTCAACATTTTCCAAATTCTTGCCATTATTTTTCAAAAGTTTAATAGTTTGCAGAAATAGATACTCAAGCCAAAGTCTGTTTTAGA GAAACTTTCCATGGAAAGTCAGAATTTCTACCACTTCCTTTTCTATCCACATTTCCAGTGCAGAAGAAACTGAGAAACAGAGCTTTTTGA AGAGAGGACAGGGCCATAGCAACAAGGACCTTCTTGGGGGATTAATGGGAGGTCAGTAGAATTAATAACCCTCCTTGGATGAGTGCTACT GTTTTCACATGGCTTCAGATGCTATCAACCTCAAAGAAATGATCTCAACAGAGAAGCTTATTCTCTCCCAACTTCTACGGTAAAATCCAG GAGTATTTTCTCTGGGGATCTGCCCACAGGACAAAGTCCATAAAAGCAAGTCCTGTCTGGACCATGTGGTTATCTGAAGCATTAGCCATC ACCAGCACAACAAACGGGGCAGGGCTTTCCAAGGTGGGGCTGGTCAGAAGGGAATCTTTGATAAGAGGCCCACAGGCAGGGAAAGCGAAA TAGGGTTGATGAGACCAGGGGAGACCTAAAAAAAAGGCAGCTTTGTGTCTTCTAGCTCCAAATATACCTGCCTTTTAGCTCACACACTGT CCTGGAGTTCTCAGACCTTTAGGGGCCCTAACACAGTTCAGTTCATACAGGGGTTCAAAAGGGACAGTGGCCCATTTGGGAGACCTTTAG GATCAATGGGAATCAATTCCATTGTTTTGCCTCAGAGTAAAGTTTCTGGCTCGGGGACAATTATAAGTTGCAAAAAGGATAGAGGCATAT CCCAAGTCTTCCTTCATTCCACAAATAATTACAAACAACCTACTGTGTGCCAGGCACTATTCTTAGCACTGGAAATACACTAGTGAAGAA GCAGATGAGGACCCTGTTTATTGTTTCTCTCCAAGAAATTCTCCAAGAATATTGTTTCTTGGAGAGAAATAATAAATAAACAAGACAATT TCTGAAAGCAATAAGTGCAATCAAGATAATTAAAGGATGCTAAAGTGTGACTTGTGGGGATTGGGAGAGAGATGCACAGACAATATTAAA GAGGAGGCATTCGAGCTTTGTTGTGAACACCGGAAGTAACATGCCGAGCGCCTGGGGGATGGAAACTCCTATAGCACCCCACAGGCTAAC AGCAAGCAGGACAAGACAAAAAGGGCAGGTGGGACATGGTAGAGATGGACCCTACCCAGGAAACAGCTCCATCAGCATCTTAGCCTGCCC CACTCTAGCCACACATACCCACGTGTGCTCCTGAGTTCAGTGTGCCCACCTCACTCCCACACCCTCACATAGACTTGGCAAGAGTAAGGA GGGAACTCCATAGAGACATTTTACCTATCTCAGGGGAGCAGCCACAAAGAAGCAAGTCTTGTAAAAGGTCTTTTGCAAAGGAGAGTGAAC CCAGCAATGAGAGATCCTTAACAGCTAGTGCCCATTAGGGGGCTAAACCTAAAGCCTGGGTGGTGATGGCTCAAACGCTAATGAGTCAGT GAATCCTTACCGACCCCCTGGCCTTTATAATCTGAGGCAACTTTGGCTGCAGCCCGGGAATGTGCAGGGCACTAGGGAATACAAGGCCTT CTTCCCTGGTTGTCTTGTAATAAAACAGCCATGGGGTTGTCCCTCCAGTCCGAGAGACTGTGATGAGGCCTACATAGCAGCGATGTGGTC AGGTAAAAATCAGGAACCCACTGAAATCTTGGGCAAGCCACCCTGCCTGCTTGTGCCTCGGTTCTCTCATATGTCATATATAGGAGGTGA GGACTCCAGCTCCACCTGCCCCAGGTGGGTGTGGTGATGATGAGGAAAGACAAGAGGCTTGCAAGGACCCTGAAGAGGTCGGAGCATCAT ACAGATTCCTTTATTAGCCCACATTCTGATGTTCCCTGGTGAGACTTGCCCCAAGCAATTGCTAGTAAATGGGGGTTAATTTCTTCTCCA CCTCCCTACTGAACAAAAAAAGAAATGCCAGACTTACTAGGAGAATCGAGTTGCTTTGAGTTTCTTTTGTTTTGTTTTGTTTTGTTTTGT TTTAAGGCTCCCCTTACACACCCTCCTTTAAGCTTTGGGTTTTCTCTCTTATAGTTTGTTGACACATGCTAAAAATGTCTTTGGAGAGAA CTTCTGCCTGATAAACACCCAATTCTAGACTGTGGGTGGATTTTCGAGCTGACGGTGGTCAATTCCTTTCATTAAGCAGTGATCTGATTT CTCCACATGGCCATTCTGCCTTCTTGGGGGCAGAGTAGATGGGCAGCAGTTCACCTTTTCAGAGAAAGAGGTCTTCTAGCCACCTGGGCT GCTACTGAATGGTTTTCTCCAGGACGCTCTACCTAATGATTATTTCTATAACATTAAGCATGGTAATAAGTAGCTTCCAATTCAATTCAT CCTAAAGCCAAAGAAAATACAGCAACACACACACACACACACACACACACACACACACACACACACACACACCACTTTATGGCAATTCTT AACTGACATTCAATGACTTACTTCTTTTCTTAGAAAATTTCCACCACATTTCTATCCCCAAGCCAACATACAATGTGAAATGAAAGCCAG TGCGTGGAGTGCAGCTGCTAAAAATTTTCAGCACAGGGCTCTTTCTGACTCTGCTCATGAGATGGTATCAGCCACCCAATGACTGGCGTA TCTTGGTCCTGTGTCTTTCTTCTTACGCTGTGTTAATGTGTTTACTTTCCATTTGGCAGAGAGACAAGAGAGACACCTCCAACTTCGACA AAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTTCTCTT ATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCAAGCGTATGTA TCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTTGTATGTGTAG CTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCAAACTTCCAGA AACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCAGAAGCTGATG TTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGAGTAAGCTTTG |
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FusionGenePPI for SPNS1_PRKCB |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SPNS1 | BCL2, BCL2L1, NLRX1, UNC93B1, CLN5, TES | PRKCB | RASGRP3, NCAM1, ADRBK1, BTK, GNB2L1, CSF2RB, YWHAG, GNA12, GNA13, RIPK4, RGS2, TIAM1, PDLIM5, NCF1, PDPK1, AFAP1, LMNB1, CDK1, RBCK1, HSPA4, IKBKG, HIST1H3A, PRKCB, DDX58, TRIM41, EGFR, TERF1, TINF2, RNF31, IBTK, KCNA5, TOP2A, HIST1H1A, LSP1, H1F0, CARD11, SDC2, ITGB2, PPP2R4, PPP1CA, TNFRSF1A, FN1, HSP90AA1, GSK3A, CASR, RB1, SYT6, HIST1H1B, MARCKS, NUMB, LYN, MBP, PRKCD, EP300, SHCBP1, DAB2, AKT1, IKBKB, CHUK, GSK3B, ARRB2, ITGB3, PRKCA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SPNS1_PRKCB |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | PRKCB | P05771 | DB08862 | Cholecystokinin | Protein kinase C beta type | small molecule | approved|investigational |
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RelatedDiseases for SPNS1_PRKCB |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PRKCB | C0004352 | Autistic Disorder | 1 | CTD_human |
| Tgene | PRKCB | C0009404 | Colorectal Neoplasms | 1 | CTD_human |
| Tgene | PRKCB | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | CTD_human |
| Tgene | PRKCB | C0018800 | Cardiomegaly | 1 | CTD_human |
| Tgene | PRKCB | C0020456 | Hyperglycemia | 1 | CTD_human |
| Tgene | PRKCB | C0023493 | Adult T-Cell Lymphoma/Leukemia | 1 | CTD_human |
| Tgene | PRKCB | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | PRKCB | C0038356 | Stomach Neoplasms | 1 | CTD_human |
| Tgene | PRKCB | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Tgene | PRKCB | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
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