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Fusion gene ID: 3553 |
FusionGeneSummary for ATR_R3HDM2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATR_R3HDM2 | Fusion gene ID: 3553 | Hgene | Tgene | Gene symbol | ATR | R3HDM2 | Gene ID | 84168 | 22864 |
| Gene name | ANTXR cell adhesion molecule 1 | R3H domain containing 2 | |
| Synonyms | ATR|GAPO|TEM8 | CAG6|PR01365 | |
| Cytomap | 2p13.3 | 12q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | anthrax toxin receptor 12310008J16Rik2810405N18Riktumor endothelial marker 8 | R3H domain-containing protein 2 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q13535 | Q9Y2K5 | |
| Ensembl transtripts involved in fusion gene | ENST00000350721, ENST00000383101, | ENST00000413953, ENST00000347140, ENST00000358907, ENST00000402412, ENST00000441731, ENST00000403821, ENST00000546843, | |
| Fusion gene scores | * DoF score | 4 X 3 X 4=48 | 7 X 8 X 6=336 |
| # samples | 4 | 7 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/336*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ATR [Title/Abstract] AND R3HDM2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ATR | GO:0031532 | actin cytoskeleton reorganization | 16762926 |
| Hgene | ATR | GO:0034446 | substrate adhesion-dependent cell spreading | 16762926 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | STAD | TCGA-VQ-AA6D-01A | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000350721 | ENST00000413953 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000350721 | ENST00000347140 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000350721 | ENST00000358907 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000350721 | ENST00000402412 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000350721 | ENST00000441731 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000350721 | ENST00000403821 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| 5CDS-intron | ENST00000350721 | ENST00000546843 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000383101 | ENST00000413953 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000383101 | ENST00000347140 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000383101 | ENST00000358907 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000383101 | ENST00000402412 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000383101 | ENST00000441731 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| In-frame | ENST00000383101 | ENST00000403821 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
| 5CDS-intron | ENST00000383101 | ENST00000546843 | ATR | chr3 | 142284963 | - | R3HDM2 | chr12 | 57650294 | - |
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FusionProtFeatures for ATR_R3HDM2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATR | R3HDM2 |
| Serine/threonine protein kinase which activatescheckpoint signaling upon genotoxic stresses such as ionizingradiation (IR), ultraviolet light (UV), or DNA replicationstalling, thereby acting as a DNA damage sensor. Recognizes thesubstrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1,MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibitDNA replication and mitosis and promote DNA repair, recombinationand apoptosis. Phosphorylates 'Ser-139' of histone variantH2AX/H2AFX at sites of DNA damage, thereby regulating DNA damageresponse mechanism. Required for FANCD2 ubiquitination. Criticalfor maintenance of fragile site stability and efficient regulationof centrosome duplication. {ECO:0000269|PubMed:10597277,ECO:0000269|PubMed:10608806, ECO:0000269|PubMed:10859164,ECO:0000269|PubMed:11114888, ECO:0000269|PubMed:11418864,ECO:0000269|PubMed:11673449, ECO:0000269|PubMed:11721054,ECO:0000269|PubMed:11865061, ECO:0000269|PubMed:12526805,ECO:0000269|PubMed:12791985, ECO:0000269|PubMed:12814551,ECO:0000269|PubMed:14657349, ECO:0000269|PubMed:14729973,ECO:0000269|PubMed:14742437, ECO:0000269|PubMed:15210935,ECO:0000269|PubMed:15314022, ECO:0000269|PubMed:15496423,ECO:0000269|PubMed:16260606, ECO:0000269|PubMed:21144835,ECO:0000269|PubMed:27723717, ECO:0000269|PubMed:27723720,ECO:0000269|PubMed:9427750, ECO:0000269|PubMed:9636169,ECO:0000269|PubMed:9925639}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000347140 | - | 20 | 24 | 908_912 | 802 | 977 | Compositional bias | Note=Poly-Gly |
| Tgene | >R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000358907 | - | 18 | 22 | 908_912 | 802 | 977 | Compositional bias | Note=Poly-Gly |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000350721 | - | 3 | 47 | 1640_2185 | 97 | 2645 | Domain | FAT |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000350721 | - | 3 | 47 | 2322_2567 | 97 | 2645 | Domain | PI3K/PI4K |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000350721 | - | 3 | 47 | 2612_2644 | 97 | 2645 | Domain | FATC |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000383101 | - | 3 | 46 | 1640_2185 | 97 | 2581 | Domain | FAT |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000383101 | - | 3 | 46 | 2322_2567 | 97 | 2581 | Domain | PI3K/PI4K |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000383101 | - | 3 | 46 | 2612_2644 | 97 | 2581 | Domain | FATC |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000350721 | - | 3 | 47 | 1329_1365 | 97 | 2645 | Repeat | Note=HEAT 2 |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000350721 | - | 3 | 47 | 799_835 | 97 | 2645 | Repeat | Note=HEAT 1 |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000383101 | - | 3 | 46 | 1329_1365 | 97 | 2581 | Repeat | Note=HEAT 2 |
| Hgene | >ATR | chr3:142284963 | chr12:57650294 | ENST00000383101 | - | 3 | 46 | 799_835 | 97 | 2581 | Repeat | Note=HEAT 1 |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000347140 | - | 20 | 24 | 288_369 | 802 | 977 | Compositional bias | Note=Ser-rich |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000347140 | - | 20 | 24 | 404_694 | 802 | 977 | Compositional bias | Note=Gln-rich |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000358907 | - | 18 | 22 | 288_369 | 802 | 977 | Compositional bias | Note=Ser-rich |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000358907 | - | 18 | 22 | 404_694 | 802 | 977 | Compositional bias | Note=Gln-rich |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000347140 | - | 20 | 24 | 169_232 | 802 | 977 | Domain | R3H |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000347140 | - | 20 | 24 | 233_310 | 802 | 977 | Domain | SUZ |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000358907 | - | 18 | 22 | 169_232 | 802 | 977 | Domain | R3H |
| Tgene | R3HDM2 | chr3:142284963 | chr12:57650294 | ENST00000358907 | - | 18 | 22 | 233_310 | 802 | 977 | Domain | SUZ |
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FusionGeneSequence for ATR_R3HDM2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000413953_chr12_57650294_-_165aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000347140_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000358907_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000402412_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000441731_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000403821_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000413953_chr12_57650294_-_165aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000347140_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000358907_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000402412_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000441731_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000403821_chr12_57650294_-_272aa MGEHGLELASMIPALRELGSATPEEYNTVVQKPRQILCQFIDRILTDVNVVAVELVKKTDSQPTSVMLLDFIQHIMKSSPLMFVNVSGSH EAKGSCIGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVHQGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADK LFTQLAMSGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLNNSVSRFKLRMAKKNYDLRILERASS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000413953_chr12_57650294_-_495nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000347140_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000358907_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000402412_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000441731_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000403821_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000413953_chr12_57650294_-_495nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000347140_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000358907_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000402412_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000441731_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000403821_chr12_57650294_-_816nt ATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCAGTGCCACACCAGAGGAATATAATACAGTTGTA CAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATGTTGTTGCTGTAGAACTTGTAAAGAAAACTGAC TCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCCCACTTATGTTTGTAAATGTGAGTGGAAGCCAT GAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTACAGTACAATCTGTCCATCTGCCCTCCCTTGCTC CATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACCGGGGCAAGAGACAAGCACTCAAATCTGCCTCC ACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCCCTGAGGGCATCACCCGTACTGAGGCGGACAAA CTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGGGGCTGCCTGGAGGGGGTGGGGGGGACAACAGT GGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTGTGTTCCCCAGCCCCCTGGCTGCCCAAAATGCC TCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACTATGACCTGAGGATCCTGGAGCGAGCCAGCTCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000413953_chr12_57650294_-_827nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGCCCTGTCATTTCAGCCCTGACACCAAGGCAGGA GGCTAGGAGGTCTACAAATAGCGACTGGGTAGCTGGTGTGAACACAGGGGGTACTGGGGGGGCTTAGCCCCCAAGGAAGAGGACCAGTTT TTCCCCAGCACCACCATCAAGGCCTCGAGGCTCCCAGCTCCCTCTACAGCCTGTGGACTGACTTAGGGAATCCCGAACGATGACAGAAAA >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000347140_chr12_57650294_-_1947nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000358907_chr12_57650294_-_1946nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000402412_chr12_57650294_-_1946nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000441731_chr12_57650294_-_986nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT >In-frame_ATR_ENST00000350721_chr3_142284963_-_R3HDM2_ENST00000403821_chr12_57650294_-_955nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000413953_chr12_57650294_-_827nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGCCCTGTCATTTCAGCCCTGACACCAAGGCAGGA GGCTAGGAGGTCTACAAATAGCGACTGGGTAGCTGGTGTGAACACAGGGGGTACTGGGGGGGCTTAGCCCCCAAGGAAGAGGACCAGTTT TTCCCCAGCACCACCATCAAGGCCTCGAGGCTCCCAGCTCCCTCTACAGCCTGTGGACTGACTTAGGGAATCCCGAACGATGACAGAAAA >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000347140_chr12_57650294_-_1947nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000358907_chr12_57650294_-_1946nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000402412_chr12_57650294_-_1946nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT ATGACCTGAGGATCCTGGAGCGAGCCAGCTCCCAATAAATGGAGGAGGGGAAAGGGACTGTCACAGAAGGAGCAAGGGCAGGGTGGAGGG GGTTGAAGGATCCTGACAGACCATGGACAGAGGCAGGAAGTAAGGAAACTGATGTTAAACTGGAACCTAAGACAGTGATGAAGATGGAAA CACAGATACCTACACTGGCATTGGACTCCTTCTTGCTCCCCTGCCATGGGTCCTCTCTTTTTCCCTGGTTGACCCCCCTTGCATCACTCT TCTTCCCATCCTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTCACCCCAGCTGGAGTGCAGTAGCACGATCT TGGCTAACTGCAACCTCCAGCTCCTGGGTTCAGGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGCACTACAGACACGCGCCACCATG CCCGGCTAATTTTTGTATTTTTAGTAGAGACGGAGTTTCACCATGTTGGCCAGGCTGGCCTCAAACTCCTGACCTCAGGTGATCCACCTG CCTTGGCCTTCCAGAGTGCTGGGATTACAGGCGTGAGCCACTGTGCCTGGCTTCCATCCTCTTCTATCATTTTTTTAAATCTCTTCTCCT ATCATAAAATTAATTTCTCATTTTTTGGTCAGGTAGAATTGGGAAAGTCCCACACTGTCCTCCTATTACCTTAACATCCCAAGCTTCCTT TCCTTTTTTGGTCTTTATGAATATATTTATATGGACAGAATTAAGATAAACAAAATTGATTGCCCCATTCTCTCACTTCCCCATCTTGTC TTCCTAGACCCCACAGAGTTAAAACTTGGGATTCCCCTGGCCCCCCCAGAACACTTGTATATTGTTTGTTTGAGGTTCGTGCCGCAGTAA CAGACACAGTATTTAATTGCACATACAGATGTTTGCTGGGTATATTCACTGTAAATTTTATTTAATCTGTTTTTTTGTTTGTTTGGGGGT >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000441731_chr12_57650294_-_986nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT >In-frame_ATR_ENST00000383101_chr3_142284963_-_R3HDM2_ENST00000403821_chr12_57650294_-_955nt TTCCGGGAGGAGTTTTGGCCTCCACACGGCTCCGTCGGGCGCCGCGCTCTTCCGGCAGCGGTAGCTTTGGAGACGCCGGGAACCCGCGTT GGCGTGGTTGACTAGTGCCTCGCAGCCTCAGCATGGGGGAACATGGCCTGGAGCTGGCTTCCATGATCCCCGCCCTGCGGGAGCTGGGCA GTGCCACACCAGAGGAATATAATACAGTTGTACAGAAGCCAAGACAAATTCTGTGTCAATTCATTGACCGGATACTTACAGATGTAAATG TTGTTGCTGTAGAACTTGTAAAGAAAACTGACTCTCAGCCAACCTCCGTGATGTTGCTTGATTTCATCCAGCATATCATGAAATCCTCCC CACTTATGTTTGTAAATGTGAGTGGAAGCCATGAGGCCAAAGGCAGTTGTATTGGTGATGGGCGCTACTCCCTTTTGGGCCAGCCATTAC AGTACAATCTGTCCATCTGCCCTCCCTTGCTCCATGGCCAGTCAACTTACACGGTGCACCAGGGACAGAGTGGACTGAAGCATGGAAACC GGGGCAAGAGACAAGCACTCAAATCTGCCTCCACTGACCTGGGGACAGCAGATGTTGTCCTGGGGCGGGTGCTGGAGGTGACAGATCTCC CTGAGGGCATCACCCGTACTGAGGCGGACAAACTCTTCACGCAGCTCGCCATGTCTGGCGCCAAGATCCAGTGGCTCAAGGATGCTCAGG GGCTGCCTGGAGGGGGTGGGGGGGACAACAGTGGGACTGCTGAGAATGGCCGCCACTCGGACCTCGCTGCCTTGTACACCATTGTGGCTG TGTTCCCCAGCCCCCTGGCTGCCCAAAATGCCTCCCTTCGTCTCAACAACTCCGTGAGTCGCTTCAAACTTCGAATGGCCAAAAAGAACT |
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FusionGenePPI for ATR_R3HDM2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ATR | BRCA1, TP53, ABL1, AP1B1, ARHGEF1, ATM, ATR, BRCA2, CHEK1, E4F1, LIG4, MRE11A, NBN, PA2G4, PIK3CA, POLD1, RAD17, RPA1, WRN, MCM7, MCM2, MSH2, CLSPN, CHD4, HDAC2, HDAC1, MTA1, MTA2, ATRIP, RHEB, H2AFX, XPC, PMS1, CDC6, TTI1, TELO2, MSH6, FANCA, TOPBP1, C19orf40, RPA2, CHEK2, MCPH1, UPF1, SMC1A, CEP164, RAD1, HUS1, RAD9A, POLN, BLM, EP300, SNIP1, FANCD2, E2F1, NCOA2, CDK9, HSP90AA1, HSPA4, XRCC5, ARRB1, CDC5L, VPRBP, DCLRE1C, DTL, SOCS1, XPA, CCNB2, CDKN2A, CDKN2C, CREB1, IKBKG, CINP, EGFR, RPA3, CLTC, YBX3, FAM133B, PABPN1, BSG, CD274, CEACAM21, VSIG2, CA14, NT5E, LYPD3, SCN2B, SCARA3, ALDH3A2, HTR6, NOSIP, PPP2R3A, RASSF1, AP3B1, TERT, ETV1, SNW1, POU5F1, USP20, AIRE, MTMR4, PDGFRB, GYPA, TNFRSF1A, TNFSF8, SCN3B, PVR, NCR3LG1, GYPB, VSIG1, VASN, OPRM1, HELQ, FANCI, UHRF2 | R3HDM2 | ELAVL1, ATXN1, YWHAB, REL, SPRY1, RBPMS, FAM168A, KRTAP3-2, C1orf94, KRTAP10-8, KRTAP10-3, NOTCH2NL, STAT5A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ATR_R3HDM2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ATR_R3HDM2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ATR | C0032273 | Pneumoconiosis | 1 | CTD_human |
| Hgene | ATR | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | ATR | C0042076 | Urologic Neoplasms | 1 | CTD_human |
| Hgene | ATR | C3281203 | CUTANEOUS TELANGIECTASIA AND CANCER SYNDROME, FAMILIAL | 1 | ORPHANET;UNIPROT |
| Tgene | R3HDM2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | R3HDM2 | C3495559 | Juvenile arthritis | 1 | CTD_human |
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