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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 3542

FusionGeneSummary for ATRX_ABCB7

check button Fusion gene summary
Fusion gene informationFusion gene name: ATRX_ABCB7
Fusion gene ID: 3542
HgeneTgene
Gene symbol

ATRX

ABCB7

Gene ID

546

22

Gene nameATRX, chromatin remodelerATP binding cassette subfamily B member 7
SynonymsJMS|MRX52|RAD54|RAD54L|XH2|XNP|ZNF-HXABC7|ASAT|Atm1p|EST140535
Cytomap

Xq21.1

Xq13.3

Type of geneprotein-codingprotein-coding
Descriptiontranscriptional regulator ATRXATP-dependent helicase ATRXX-linked helicase IIX-linked nuclear proteinalpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)ATP-binding cassette sub-family B member 7, mitochondrialABC transporter 7 proteinATP-binding cassette transporter 7ATP-binding cassette, sub-family B (MDR/TAP), member 7
Modification date2018051920180525
UniProtAcc

P46100

O75027

Ensembl transtripts involved in fusion geneENST00000373344, ENST00000395603, 
ENST00000480283, ENST00000373341, 
ENST00000253577, ENST00000339447, 
ENST00000373394, ENST00000534570, 
Fusion gene scores* DoF score9 X 4 X 6=2163 X 4 X 3=36
# samples 93
** MAII scorelog2(9/216*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/36*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATRX [Title/Abstract] AND ABCB7 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATRX

GO:0006334

nucleosome assembly

20651253

HgeneATRX

GO:0006338

chromatin remodeling

20651253


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-HB-A3YV-01AATRXchrX

77041468

-ABCB7chrX

74334669

-
TCGALDSARCTCGA-HB-A3YV-01AATRXchrX

77041332

-ABCB7chrX

74318897

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000373344ENST00000253577ATRXchrX

77041468

-ABCB7chrX

74334669

-
In-frameENST00000373344ENST00000339447ATRXchrX

77041468

-ABCB7chrX

74334669

-
In-frameENST00000373344ENST00000373394ATRXchrX

77041468

-ABCB7chrX

74334669

-
5CDS-intronENST00000373344ENST00000534570ATRXchrX

77041468

-ABCB7chrX

74334669

-
In-frameENST00000395603ENST00000253577ATRXchrX

77041468

-ABCB7chrX

74334669

-
In-frameENST00000395603ENST00000339447ATRXchrX

77041468

-ABCB7chrX

74334669

-
In-frameENST00000395603ENST00000373394ATRXchrX

77041468

-ABCB7chrX

74334669

-
5CDS-intronENST00000395603ENST00000534570ATRXchrX

77041468

-ABCB7chrX

74334669

-
5UTR-3CDSENST00000480283ENST00000253577ATRXchrX

77041468

-ABCB7chrX

74334669

-
5UTR-3CDSENST00000480283ENST00000339447ATRXchrX

77041468

-ABCB7chrX

74334669

-
5UTR-3CDSENST00000480283ENST00000373394ATRXchrX

77041468

-ABCB7chrX

74334669

-
5UTR-intronENST00000480283ENST00000534570ATRXchrX

77041468

-ABCB7chrX

74334669

-
intron-3CDSENST00000373341ENST00000253577ATRXchrX

77041468

-ABCB7chrX

74334669

-
intron-3CDSENST00000373341ENST00000339447ATRXchrX

77041468

-ABCB7chrX

74334669

-
intron-3CDSENST00000373341ENST00000373394ATRXchrX

77041468

-ABCB7chrX

74334669

-
intron-intronENST00000373341ENST00000534570ATRXchrX

77041468

-ABCB7chrX

74334669

-
intron-3CDSENST00000373344ENST00000253577ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000373344ENST00000339447ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000373344ENST00000373394ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000373344ENST00000534570ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-3CDSENST00000395603ENST00000253577ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000395603ENST00000339447ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000395603ENST00000373394ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000395603ENST00000534570ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-3CDSENST00000480283ENST00000253577ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000480283ENST00000339447ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000480283ENST00000373394ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000480283ENST00000534570ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-3CDSENST00000373341ENST00000253577ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000373341ENST00000339447ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000373341ENST00000373394ATRXchrX

77041332

-ABCB7chrX

74318897

-
intron-intronENST00000373341ENST00000534570ATRXchrX

77041332

-ABCB7chrX

74318897

-

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FusionProtFeatures for ATRX_ABCB7


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATRX

P46100

ABCB7

O75027

Could be involved in the transport of heme from themitochondria to the cytosol. Plays a central role in thematuration of cytosolic iron-sulfur (Fe/S) cluster-containingproteins.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016140_43656754DomainABC transmembrane type-1
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016472_70656754DomainABC transporter
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016140_43656753DomainABC transmembrane type-1
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016472_70656753DomainABC transporter
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016505_51656754Nucleotide bindingATP
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016505_51656753Nucleotide bindingATP
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016141_16156754TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016186_20656754TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016260_28056754TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016291_31156754TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016383_40356754TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000253577-016410_43056754TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016141_16156753TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016186_20656753TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016260_28056753TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016291_31156753TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016383_40356753TransmembraneHelical
TgeneABCB7chrX:77041468chrX:74334669ENST00000373394-016410_43056753TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351151_115662493Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351166_116962493Compositional biasNote=Poly-Lys
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351202_120662493Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351259_126662493Compositional biasNote=Poly-Asp
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351443_146662493Compositional biasNote=Poly-Glu
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351499_150262493Compositional biasNote=Poly-Glu
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351929_193962493Compositional biasNote=Poly-Lys
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351941_194862493Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1352222_222562493Compositional biasNote=Poly-Lys
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1352262_226562493Compositional biasNote=Poly-Glu
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1352420_242562493Compositional biasNote=Poly-Gln
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-135745_75062493Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341151_115662455Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341166_116962455Compositional biasNote=Poly-Lys
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341202_120662455Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341259_126662455Compositional biasNote=Poly-Asp
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341443_146662455Compositional biasNote=Poly-Glu
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341499_150262455Compositional biasNote=Poly-Glu
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341929_193962455Compositional biasNote=Poly-Lys
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341941_194862455Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1342222_222562455Compositional biasNote=Poly-Lys
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1342262_226562455Compositional biasNote=Poly-Glu
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1342420_242562455Compositional biasNote=Poly-Gln
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-134745_75062455Compositional biasNote=Poly-Ser
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351581_176862493DomainHelicase ATP-binding
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-135159_29662493DomainADD
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1352025_220562493DomainHelicase C-terminal
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341581_176862455DomainHelicase ATP-binding
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-134159_29662455DomainADD
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1342025_220562455DomainHelicase C-terminal
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351719_172262493MotifNote=DEGH box
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-135581_59462493MotifNote=PxVxL motif
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341719_172262455MotifNote=DEGH box
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-134581_59462455MotifNote=PxVxL motif
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351594_160162493Nucleotide bindingATP
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341594_160162455Nucleotide bindingATP
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-135170_20662493Zinc fingerGATA-type%3B atypical
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-135217_27262493Zinc fingerPHD-type%3B atypical
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-134170_20662455Zinc fingerGATA-type%3B atypical
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-134217_27262455Zinc fingerPHD-type%3B atypical


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FusionGeneSequence for ATRX_ABCB7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000253577_chrX_74334669_-_704aa
MTAEPMSRFQSHXKVSHGRDWEKAIQDSSXMLQRLSRYGHXXKRGHVGMVMQEEDSTQTQKKGXKMLILGKSXKQCFLMCGPKTGQIYEL
ELPFRWDFWVVQRPXILWFPSCLNMLXTASTRCRETCXTXVMHQIQLQPWQQQFXLAMVYQELELLFLTKFEMQYLARXPRIQSEEXPKM
SFSIFTTWIWVFTXADRRELYLRLLTEEQGVSVLSXVLWYLIFFPSCLKXCLSVVFCITNAVPSLLWXPLEHLVHTQHSQLQSHGGELDL
EXKXTKQIMMQVMLLXTHCXIMKLXSILIMKDMKHRDMMDFXRRMRLLHXKVPLLWLCXTLVKVLFSVSVXQLXWCSPVRELWQVPLLLE
IXXWXMDCFFSFHYPXTFWELYIERLDKHSXIXTPCLLYSRXTPKLKTKXWHLPFRSHHRQLPWPLIMCILNTLRARKSLVEYPLKSLQE
RKWPLXEVVGQGKAQXXGYYFASMSLKRVAFILLVKIYKMXAWKAFGGQWEWYLRMLSSSIILFITTSYMETSVLHLRKCMQWQNXLDFM
MQFFECHMDMTPKXGNEDSSFQEEKSKEXQLQEPFXRTPQSYSMMKLLHRXIRLLKRLFLVPXRMWSNTELLFSLHTDCQQWLMQMKSLS

>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000339447_chrX_74334669_-_663aa
MTAEPMRFQSHXKVSHGRDWEKAIQDSSXMLQRLSRYGHXXKRGHVGMVMQEEDSTQTQKKGPXILWFPSCLNMLXTASTRCRETCXTXV
MHQIQLQPWQQQFXLAMVYQELELLFLTKFEMQYLARXPRIQSEEXPKMSFSIFTTWIWVFTXADRRELYLRLLTEEQGVSVLSXVLWYL
IFFPSCLKXCLSVVFCITNAVPSLLWXPLEHLVHTQHSQLQSHGGELDLEXKXTKQIMMQVMLLXTHCXIMKLXSILIMKDMKHRDMMDF
XRRMRLLHXKVPLLWLCXTLVKVLFSVSVXQLXWCSPVRELWQVPLLLEIXXWXMDCFFSFHYPXTFWELYIERLDKHSXIXTPCLLYSR
XTPKLKTKXWHLPFRSHHRQLPWPLIMCILNTLRARKSLVEYPLKSLQERKWPLXEVVGQGKAQXXGYYFASMSLKRVAFILLVKIYKMX
AWKAFGGQWEWYLRMLSSSIILFITTSYMETSVLHLRKCMQWQNXLDFMMQFFECHMDMTPKXGNEDSSFQEEKSKEXQLQEPFXRTPQS
YSMMKLLHRXIRLLKRLFLVPXRMWSNTELLFSLHTDCQQWLMQMKSLSWIRVRXPNVVPTMVCLLTLIVSIQKCGIHRAAVCRTMITPN

>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000373394_chrX_74334669_-_703aa
MTAEPMRFQSHXKVSHGRDWEKAIQDSSXMLQRLSRYGHXXKRGHVGMVMQEEDSTQTQKKGXKMLILGKSXKQCFLMCGPKTGQIYELE
LPFRWDFWVVQRPXILWFPSCLNMLXTASTRCRETCXTXVMHQIQLQPWQQQFXLAMVYQELELLFLTKFEMQYLARXPRIQSEEXPKMS
FSIFTTWIWVFTXADRRELYLRLLTEEQGVSVLSXVLWYLIFFPSCLKXCLSVVFCITNAVPSLLWXPLEHLVHTQHSQLQSHGGELDLE
XKXTKQIMMQVMLLXTHCXIMKLXSILIMKDMKHRDMMDFXRRMRLLHXKVPLLWLCXTLVKVLFSVSVXQLXWCSPVRELWQVPLLLEI
XXWXMDCFFSFHYPXTFWELYIERLDKHSXIXTPCLLYSRXTPKLKTKXWHLPFRSHHRQLPWPLIMCILNTLRARKSLVEYPLKSLQER
KWPLXEVVGQGKAQXXGYYFASMSLKRVAFILLVKIYKMXAWKAFGGQWEWYLRMLSSSIILFITTSYMETSVLHLRKCMQWQNXLDFMM
QFFECHMDMTPKXGNEDSSFQEEKSKEXQLQEPFXRTPQSYSMMKLLHRXIRLLKRLFLVPXRMWSNTELLFSLHTDCQQWLMQMKSLSW

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000253577_chrX_74334669_-_704aa
MTAEPMSRFQSHXKVSHGRDWEKAIQDSSXMLQRLSRYGHXXKRGHVGMVMQEEDSTQTQKKGXKMLILGKSXKQCFLMCGPKTGQIYEL
ELPFRWDFWVVQRPXILWFPSCLNMLXTASTRCRETCXTXVMHQIQLQPWQQQFXLAMVYQELELLFLTKFEMQYLARXPRIQSEEXPKM
SFSIFTTWIWVFTXADRRELYLRLLTEEQGVSVLSXVLWYLIFFPSCLKXCLSVVFCITNAVPSLLWXPLEHLVHTQHSQLQSHGGELDL
EXKXTKQIMMQVMLLXTHCXIMKLXSILIMKDMKHRDMMDFXRRMRLLHXKVPLLWLCXTLVKVLFSVSVXQLXWCSPVRELWQVPLLLE
IXXWXMDCFFSFHYPXTFWELYIERLDKHSXIXTPCLLYSRXTPKLKTKXWHLPFRSHHRQLPWPLIMCILNTLRARKSLVEYPLKSLQE
RKWPLXEVVGQGKAQXXGYYFASMSLKRVAFILLVKIYKMXAWKAFGGQWEWYLRMLSSSIILFITTSYMETSVLHLRKCMQWQNXLDFM
MQFFECHMDMTPKXGNEDSSFQEEKSKEXQLQEPFXRTPQSYSMMKLLHRXIRLLKRLFLVPXRMWSNTELLFSLHTDCQQWLMQMKSLS

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000339447_chrX_74334669_-_663aa
MTAEPMRFQSHXKVSHGRDWEKAIQDSSXMLQRLSRYGHXXKRGHVGMVMQEEDSTQTQKKGPXILWFPSCLNMLXTASTRCRETCXTXV
MHQIQLQPWQQQFXLAMVYQELELLFLTKFEMQYLARXPRIQSEEXPKMSFSIFTTWIWVFTXADRRELYLRLLTEEQGVSVLSXVLWYL
IFFPSCLKXCLSVVFCITNAVPSLLWXPLEHLVHTQHSQLQSHGGELDLEXKXTKQIMMQVMLLXTHCXIMKLXSILIMKDMKHRDMMDF
XRRMRLLHXKVPLLWLCXTLVKVLFSVSVXQLXWCSPVRELWQVPLLLEIXXWXMDCFFSFHYPXTFWELYIERLDKHSXIXTPCLLYSR
XTPKLKTKXWHLPFRSHHRQLPWPLIMCILNTLRARKSLVEYPLKSLQERKWPLXEVVGQGKAQXXGYYFASMSLKRVAFILLVKIYKMX
AWKAFGGQWEWYLRMLSSSIILFITTSYMETSVLHLRKCMQWQNXLDFMMQFFECHMDMTPKXGNEDSSFQEEKSKEXQLQEPFXRTPQS
YSMMKLLHRXIRLLKRLFLVPXRMWSNTELLFSLHTDCQQWLMQMKSLSWIRVRXPNVVPTMVCLLTLIVSIQKCGIHRAAVCRTMITPN

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000373394_chrX_74334669_-_703aa
MTAEPMRFQSHXKVSHGRDWEKAIQDSSXMLQRLSRYGHXXKRGHVGMVMQEEDSTQTQKKGXKMLILGKSXKQCFLMCGPKTGQIYELE
LPFRWDFWVVQRPXILWFPSCLNMLXTASTRCRETCXTXVMHQIQLQPWQQQFXLAMVYQELELLFLTKFEMQYLARXPRIQSEEXPKMS
FSIFTTWIWVFTXADRRELYLRLLTEEQGVSVLSXVLWYLIFFPSCLKXCLSVVFCITNAVPSLLWXPLEHLVHTQHSQLQSHGGELDLE
XKXTKQIMMQVMLLXTHCXIMKLXSILIMKDMKHRDMMDFXRRMRLLHXKVPLLWLCXTLVKVLFSVSVXQLXWCSPVRELWQVPLLLEI
XXWXMDCFFSFHYPXTFWELYIERLDKHSXIXTPCLLYSRXTPKLKTKXWHLPFRSHHRQLPWPLIMCILNTLRARKSLVEYPLKSLQER
KWPLXEVVGQGKAQXXGYYFASMSLKRVAFILLVKIYKMXAWKAFGGQWEWYLRMLSSSIILFITTSYMETSVLHLRKCMQWQNXLDFMM
QFFECHMDMTPKXGNEDSSFQEEKSKEXQLQEPFXRTPQSYSMMKLLHRXIRLLKRLFLVPXRMWSNTELLFSLHTDCQQWLMQMKSLSW


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000253577_chrX_74334669_-_2114nt
ATGACCGCTGAGCCCATGAGCAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAG
ATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAA
AAGAAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTATGTGTGGCCCAAAGACAGGCCAGATCTACGAGCTA
GAGTTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCTCA
ACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTAT
CAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAATG
TCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAGGG
GTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAAT
GCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATTTA
GAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAATG
AAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAACT
TTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAG
ATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACTCA
TAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACAGA
CAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAA
AGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCA
TTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCC
ATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCATG
ATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAA
TTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCTTG
GTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGTCT
TGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACAGA
GCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAG

>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000339447_chrX_74334669_-_1991nt
ATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATG
CTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAG
AAGGGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAACCTGAGTG
ATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTC
GAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTT
TTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTA
ATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAA
CACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATTTAGAATAGAAATGAACAAAGCAGATAATGATGCAG
GTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTT
TGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAA
CAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAGATCTAGTAATGGTGAATGGACTGCTTTTTCAGC
TTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACTCATAGATATGAACACCTTGTTTACTCTACTCAAGG
TAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAATGTGCATTTTG
AATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAG
GGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTTATCTTGCTGGTCAAAATATACAAGATGTGA
GCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATATGGAA
ACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATTCTTCGAATGCCACATGGATATGACA
CCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCA
TACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTT
CTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCC
ACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACAGAGCAGCCGTGTGCAGAACCATGATAACCCCAAAT
GGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACT

>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000373394_chrX_74334669_-_2111nt
ATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATG
CTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAG
AAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTATGTGTGGCCCAAAGACAGGCCAGATCTACGAGCTAGAG
TTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACC
AGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAA
GAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAATGTCT
TTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAGGGGTA
TCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCG
GTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATTTAGAA
TAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAATGAAA
GATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTG
GTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAGATC
TAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACTCATAG
ATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACAGACAG
CTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGA
AAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTT
ATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATA
ATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATG
CAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTG
CAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCTTGGTG
CCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGTCTTGG
ATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACAGAGCA
GCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAA

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000253577_chrX_74334669_-_2114nt
ATGACCGCTGAGCCCATGAGCAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAG
ATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAA
AAGAAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTATGTGTGGCCCAAAGACAGGCCAGATCTACGAGCTA
GAGTTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCTCA
ACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTAT
CAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAATG
TCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAGGG
GTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAAT
GCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATTTA
GAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAATG
AAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAACT
TTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAG
ATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACTCA
TAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACAGA
CAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAA
AGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCA
TTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCC
ATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCATG
ATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAA
TTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCTTG
GTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGTCT
TGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACAGA
GCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAG

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000339447_chrX_74334669_-_1991nt
ATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATG
CTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAG
AAGGGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAACCTGAGTG
ATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTC
GAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTT
TTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTA
ATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAA
CACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATTTAGAATAGAAATGAACAAAGCAGATAATGATGCAG
GTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTT
TGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAA
CAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAGATCTAGTAATGGTGAATGGACTGCTTTTTCAGC
TTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACTCATAGATATGAACACCTTGTTTACTCTACTCAAGG
TAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAATGTGCATTTTG
AATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAG
GGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTTATCTTGCTGGTCAAAATATACAAGATGTGA
GCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATATGGAA
ACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATTCTTCGAATGCCACATGGATATGACA
CCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCA
TACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTT
CTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCC
ACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACAGAGCAGCCGTGTGCAGAACCATGATAACCCCAAAT
GGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACT

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000373394_chrX_74334669_-_2111nt
ATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATG
CTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAG
AAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTATGTGTGGCCCAAAGACAGGCCAGATCTACGAGCTAGAG
TTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACC
AGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAA
GAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAATGTCT
TTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAGGGGTA
TCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCG
GTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATTTAGAA
TAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAATGAAA
GATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTG
GTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAGATC
TAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACTCATAG
ATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACAGACAG
CTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGA
AAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTT
ATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATA
ATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATG
CAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTG
CAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCTTGGTG
CCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGTCTTGG
ATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACAGAGCA
GCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000253577_chrX_74334669_-_2419nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGCAGATTCCAGAGTCATTAAAAAGTATCACATGGCA
GAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCA
TGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTA
TGTGTGGCCCAAAGACAGGCCAGATCTACGAGCTAGAGTTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGT
TCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAAC
CATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGT
AGCCCAGAATTCAATCCGAAGAATAGCCAAAAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGG
AGCTTTATCTAAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGA
AGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATT
CACAGTTGCAGTCACACGGTGGAGAACTAGATTTAGAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACT
GCTGAATTATGAAACTGTGAAGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTC
ATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAG
TCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAGATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCT
GGGAACTGTATATAGAGAGACTAGACAAGCACTCATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAA
AGTGATGGCATCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGT
CCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCT
ATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGC
AGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGA
AGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACT
CAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTC
ATCGTTAGATTCGATTACTGAAGAGACTATTCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATT
GTCAACAGTGGTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCC
TCATAGTATCTATTCAGAAATGTGGCATACACAGAGCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATAT
ATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGCTAAGTCACATAAGA

>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000339447_chrX_74334669_-_2294nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAG
ATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGG
TCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCT
CAACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGT
ATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAA
TGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAG
GGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAA
ATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATT
TAGAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAA
TGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAA
CTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGG
AGATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACT
CATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACA
GACAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGG
AAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAG
CATTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTT
CCATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCA
TGATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGC
AATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCT
TGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGT
CTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACA
GAGCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGA
AGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGCTAAGTCACATAAGACATTTTCTTTTTTTGTTGTTTTGGACTACATAT

>In-frame_ATRX_ENST00000373344_chrX_77041468_-_ABCB7_ENST00000373394_chrX_74334669_-_2412nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAG
ATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGG
TCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTATGT
GTGGCCCAAAGACAGGCCAGATCTACGAGCTAGAGTTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGTTCC
CTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCAT
GGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGC
CCAGAATTCAATCCGAAGAATAGCCAAAAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGC
TTTATCTAAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGT
GATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCAC
AGTTGCAGTCACACGGTGGAGAACTAGATTTAGAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCT
GAATTATGAAACTGTGAAGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATT
GAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCA
GGGAATTGTGGCAGGTACCCTTACTGTTGGAGATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGG
AACTGTATATAGAGAGACTAGACAAGCACTCATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGT
GATGGCATCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCT
TAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATT
ATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGT
GGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGT
GTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAA
GCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATC
GTTAGATTCGATTACTGAAGAGACTATTCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTC
AACAGTGGTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCA
TAGTATCTATTCAGAAATGTGGCATACACAGAGCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATC
CAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGCTAAGTCACATAAGACAT

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000253577_chrX_74334669_-_2419nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGCAGATTCCAGAGTCATTAAAAAGTATCACATGGCA
GAGATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCA
TGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTA
TGTGTGGCCCAAAGACAGGCCAGATCTACGAGCTAGAGTTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGT
TCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAAC
CATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGT
AGCCCAGAATTCAATCCGAAGAATAGCCAAAAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGG
AGCTTTATCTAAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGA
AGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATT
CACAGTTGCAGTCACACGGTGGAGAACTAGATTTAGAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACT
GCTGAATTATGAAACTGTGAAGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTC
ATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAG
TCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAGATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCT
GGGAACTGTATATAGAGAGACTAGACAAGCACTCATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAA
AGTGATGGCATCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGT
CCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCT
ATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGC
AGTGGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGA
AGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACT
CAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTC
ATCGTTAGATTCGATTACTGAAGAGACTATTCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATT
GTCAACAGTGGTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCC
TCATAGTATCTATTCAGAAATGTGGCATACACAGAGCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATAT
ATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGCTAAGTCACATAAGA

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000339447_chrX_74334669_-_2294nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAG
ATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGG
TCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGGCCATGAATATTGTGGTTCCCTTCATGTTTAAATATGCTGTAGACAGCCT
CAACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGT
ATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAAAAA
TGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGCTTTATCTAAGGCTATTGACAGAGGAACAAG
GGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAA
ATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATT
TAGAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGAAGTATTTTAATAA
TGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATTGAAAAGTACCTCTACTCTGGCTATGCTGAA
CTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGG
AGATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGCACT
CATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGTGATGGCATCTCCCCTTCAGATCACACCACA
GACAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGG
AAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAG
CATTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGGATGCTGTCCTCTT
CCATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGTGTATGCAGTGGCAAAATTAGCTGGACTTCA
TGATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGC
AATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTATTCT
TGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTCAACAGTGGTTGATGCAGATGAAATCATTGT
CTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACA
GAGCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGA
AGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGCTAAGTCACATAAGACATTTTCTTTTTTTGTTGTTTTGGACTACATAT

>In-frame_ATRX_ENST00000395603_chrX_77041468_-_ABCB7_ENST00000373394_chrX_74334669_-_2412nt
CTCGGCCCAACAAAATGGCGGCGGCAGCGGTGTCGCTTTGTTTCCGCGGCTCCTGCGGCGGTGGCAGTGGTAGCGGCCTTTGAGCTGTGG
GGAGGTTCCAGCAGCAGCTACAGTGACGACTAAGACTCCAGTGCATTTCTATCGTAACCGGGCGCGGGGGAGCGCAGATCGGCGCCCAGC
AATCACAGAAGCCGACAAGGCGTTCAAGCGAAAACATGACCGCTGAGCCCATGAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAG
ATTGGGAAAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGACATGTTGGCATGG
TCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGTTAAAAGATGTTGATACTCGGAAAATCATAAAAGCAATGCTTTCTTATGT
GTGGCCCAAAGACAGGCCAGATCTACGAGCTAGAGTTGCCATTTCGCTGGGATTTTTGGGTGGTGCAAAGGCCATGAATATTGTGGTTCC
CTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAACCTGAGTGATGCACCAAATACAGTTGCAACCAT
GGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGAGCTGGAGCTGCTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGC
CCAGAATTCAATCCGAAGAATAGCCAAAAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGC
TTTATCTAAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCATCATGTTTGAAGT
GATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAGTTTGCTTTGGTAACCCTTGGAACACTTGGTACATACACAGCATTCAC
AGTTGCAGTCACACGGTGGAGAACTAGATTTAGAATAGAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCT
GAATTATGAAACTGTGAAGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTCATT
GAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACAGCTATAATGGTGCTCGCCAGTCA
GGGAATTGTGGCAGGTACCCTTACTGTTGGAGATCTAGTAATGGTGAATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGG
AACTGTATATAGAGAGACTAGACAAGCACTCATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGT
GATGGCATCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGGGCCAGAAAGTCCT
TAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGAAAGTGGCCATTGTAGGAGGTAGTGGGTCAGGGAAAAGCACAATAGTGAGGCTATT
ATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTTATCTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGT
GGGAGTGGTACCTCAGGATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGAAGT
GTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATTCTTCGAATGCCACATGGATATGACACCCAAGTAGGGGAACGAGGACTCAA
GCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTGCAAGAGCCATTTTGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATC
GTTAGATTCGATTACTGAAGAGACTATTCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTC
AACAGTGGTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGCTTGCTAACCCTCA
TAGTATCTATTCAGAAATGTGGCATACACAGAGCAGCCGTGTGCAGAACCATGATAACCCCAAATGGGAAGCAAAGAAAGAAAATATATC
CAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAATTGTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGCTAAGTCACATAAGACAT


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FusionGenePPI for ATRX_ABCB7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ATRXEIF4A2, EZH2, CCSER2, KIAA1377, LUC7L2, PTN, PTPN4, RAD51, SMC1A, CBX5, H3F3A, H3F3B, DAXX, HDAC4, HIST1H3A, WRN, CALM1, SVIL, ZBED1, HIST2H3C, BLM, NEK1, ZNF512B, PRKDC, RAD50, XRCC5, MRE11A, XRCC6, SUPT16H, NBN, SSRP1, HIST1H4J, HIST2H2BE, RPA1, TP53, HIST1H1C, RAD9A, HIST1H2BL, HIST1H2AB, RAD1, PML, NSD1, SUMO2, TMPO, CNOT1, LRRK2, H2AFY, SNW1, ZNF274, TRIM28, SETDB1, BMI1, AURKA, HIST1H4A, WDR1, EAF1, DDX20, NAF1, EIF2AK1, AP3B1, POLD1, RBM14, MFAP1ABCB7FECH, ICT1, PCK1, APP, MRPL10, ATP6V1D, PDCD6, NDUFB6, UQCRC1, MTCH1, SDF4, UNK, NTRK1, ACAT1, CKB, CKM, FKBP8, MAT2A, RAB2A, YBX3, EPRS, RPN1, FOXS1, FAF2, COQ9, NDUFA4, UBC, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1351189_132662493DAXX
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1341189_132662455DAXX
HgeneATRXchrX:77041468chrX:74334669ENST00000373344-1352010_228062493MECP2
HgeneATRXchrX:77041468chrX:74334669ENST00000395603-1342010_228062455MECP2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ATRX_ABCB7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ATRX_ABCB7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneATRXC1845055ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME, NONDELETION TYPE, X-LINKED11CTD_human;ORPHANET;UNIPROT
HgeneATRXC0796003Juberg-Marsidi syndrome5CTD_human;ORPHANET;UNIPROT
HgeneATRXC0017638Glioma2CTD_human
HgeneATRXC0027819Neuroblastoma2CTD_human
HgeneATRXC0010417Cryptorchidism1CTD_human;HPO
HgeneATRXC0010606Adenoid Cystic Carcinoma1CTD_human
HgeneATRXC0018273Growth Disorders1CTD_human
HgeneATRXC0030297Pancreatic Neoplasm1CTD_human
HgeneATRXC0030846Penile Diseases1CTD_human
HgeneATRXC0039978Thoracic Diseases1CTD_human
HgeneATRXC0206754Neuroendocrine Tumors1CTD_human
HgeneATRXC0376634Craniofacial Abnormalities1CTD_human
HgeneATRXC1136249Mental Retardation, X-Linked1CTD_human
HgeneATRXC3463824MYELODYSPLASTIC SYNDROME1CTD_human;HPO
TgeneABCB7C1845028ANEMIA, SIDEROBLASTIC, AND SPINOCEREBELLAR ATAXIA5CTD_human;ORPHANET;UNIPROT
TgeneABCB7C0002896Sideroblastic anemia2CTD_human;HPO
TgeneABCB7C0004134Ataxia1CTD_human