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Fusion gene ID: 35358 |
FusionGeneSummary for SOCS7_SRCIN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SOCS7_SRCIN1 | Fusion gene ID: 35358 | Hgene | Tgene | Gene symbol | SOCS7 | SRCIN1 | Gene ID | 122809 | 80725 |
| Gene name | suppressor of cytokine signaling 4 | SRC kinase signaling inhibitor 1 | |
| Synonyms | SOCS7 | P140|SNIP | |
| Cytomap | 14q22.3 | 17q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | suppressor of cytokine signaling 4SH2 domain containing SOCS box proteinSOCS-4SOCS-7suppressor of cytokine signaling 7 | SRC kinase signaling inhibitor 1P130Cas-associated proteinSNAP-25-interacting proteinSNAP25-interacting proteinp140Cap | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | O14512 | Q9C0H9 | |
| Ensembl transtripts involved in fusion gene | ENST00000331159, ENST00000577233, | ENST00000264659, ENST00000578925, ENST00000398579, | |
| Fusion gene scores | * DoF score | 8 X 6 X 6=288 | 7 X 5 X 4=140 |
| # samples | 10 | 7 | |
| ** MAII score | log2(10/288*10)=-1.52606881166759 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/140*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SOCS7 [Title/Abstract] AND SRCIN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SOCS7 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity | 15590694 |
| Tgene | SRCIN1 | GO:0061098 | positive regulation of protein tyrosine kinase activity | 17525734 |
| Tgene | SRCIN1 | GO:0061099 | negative regulation of protein tyrosine kinase activity | 17525734 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-A8-A07I-01A | SOCS7 | chr17 | 36533668 | + | SRCIN1 | chr17 | 36705446 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000331159 | ENST00000264659 | SOCS7 | chr17 | 36533668 | + | SRCIN1 | chr17 | 36705446 | - |
| In-frame | ENST00000331159 | ENST00000578925 | SOCS7 | chr17 | 36533668 | + | SRCIN1 | chr17 | 36705446 | - |
| 5CDS-5UTR | ENST00000331159 | ENST00000398579 | SOCS7 | chr17 | 36533668 | + | SRCIN1 | chr17 | 36705446 | - |
| In-frame | ENST00000577233 | ENST00000264659 | SOCS7 | chr17 | 36533668 | + | SRCIN1 | chr17 | 36705446 | - |
| In-frame | ENST00000577233 | ENST00000578925 | SOCS7 | chr17 | 36533668 | + | SRCIN1 | chr17 | 36705446 | - |
| 5CDS-5UTR | ENST00000577233 | ENST00000398579 | SOCS7 | chr17 | 36533668 | + | SRCIN1 | chr17 | 36705446 | - |
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FusionProtFeatures for SOCS7_SRCIN1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SOCS7 | SRCIN1 |
| Regulates signaling cascades probably through proteinubiquitination and/or sequestration. Functions in insulinsignaling and glucose homeostasis through IRS1 ubiquitination andsubsequent proteasomal degradation. Inhibits also prolactin,growth hormone and leptin signaling by preventing STAT3 and STAT5activation, sequestering them in the cytoplasm and reducing theirbinding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates theubiquitination and subsequent proteasomal degradation of targetproteins (By similarity). {ECO:0000250,ECO:0000269|PubMed:15677474, ECO:0000269|PubMed:16127460}. | Acts as a negative regulator of SRC by activating CSKwhich inhibits SRC activity and downstream signaling, leading toimpaired cell spreading and migration. Regulates dendritic spinemorphology. Involved in calcium-dependent exocytosis. May play arole in neurotransmitter release or synapse maintenance.{ECO:0000269|PubMed:14657239, ECO:0000269|PubMed:17525734,ECO:0000269|PubMed:19146815}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 141_148 | 496 | 404 | Compositional bias | Note=Poly-Gly |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 180_187 | 496 | 404 | Compositional bias | Note=Poly-Gln |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 188_197 | 496 | 404 | Compositional bias | Note=Poly-Pro |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 303_312 | 496 | 404 | Compositional bias | Note=Poly-Pro |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 343_350 | 496 | 404 | Compositional bias | Note=Poly-Pro |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 82_97 | 496 | 404 | Compositional bias | Note=Poly-Pro |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 400_509 | 496 | 404 | Domain | SH2 |
| Hgene | SOCS7 | chr17:36533668 | chr17:36705446 | ENST00000577233 | + | 7 | 10 | 504_554 | 496 | 404 | Domain | SOCS box |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | SRCIN1 | chr17:36533668 | chr17:36705446 | ENST00000264659 | - | 14 | 19 | 654_674 | 987 | 1184 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | SRCIN1 | chr17:36533668 | chr17:36705446 | ENST00000264659 | - | 14 | 19 | 726_746 | 987 | 1184 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | SRCIN1 | chr17:36533668 | chr17:36705446 | ENST00000264659 | - | 14 | 19 | 471_504 | 987 | 1184 | Compositional bias | Note=Pro-rich |
| Tgene | SRCIN1 | chr17:36533668 | chr17:36705446 | ENST00000264659 | - | 14 | 19 | 956_1014 | 987 | 1184 | Compositional bias | Note=Pro-rich |
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FusionGeneSequence for SOCS7_SRCIN1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SOCS7_ENST00000331159_chr17_36533668_+_SRCIN1_ENST00000264659_chr17_36705446_-_659aa MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPP PPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRT QSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRE LEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKN GKFLYFLRSRVPDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARP ASTPPIMASAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQATKPSKEMSGSNETSS >In-frame_SOCS7_ENST00000331159_chr17_36533668_+_SRCIN1_ENST00000578925_chr17_36705446_-_659aa MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPP PPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRT QSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDAFPRIAPIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRE LEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRMEHYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKN GKFLYFLRSRVPDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTSKKDSAFIKKAESEELEVQKPQVKLRRAVSEVARP ASTPPIMASAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDKSKHGKQRAEYMRIQAQQQATKPSKEMSGSNETSS >In-frame_SOCS7_ENST00000577233_chr17_36533668_+_SRCIN1_ENST00000264659_chr17_36705446_-_693aa MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPP PPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRT QSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRME HYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTS KKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDK >In-frame_SOCS7_ENST00000577233_chr17_36533668_+_SRCIN1_ENST00000578925_chr17_36705446_-_693aa MVFRNVGRPPEEEDVEAAPEPGPSELLCPRHRCALDPKALPPGLALERTWGPAAGLEAQLAALGLGQPAGPGVKTVGGGCCPCPCPPQPP PPQPQPPAAAPQAGEDPTETSDALLVLEGLESEAESLETNSCSEEELSSPGRGGGGGGRLLLQPPGPELPPVPFPLQDLVPLGRLSRGEQ QQQQQQQPPPPPPPPGPLRPLAGPSRKGSFKIRLSRLFRTKSCNGGSGGGDGTGKRPSGELAASAASLTDMGGSAGRELDAGRKPKLTRT QSAFSPVSFSPLFTGETVSLVDVDISQRGLTSPHPPTPPPPPRRSLSLLDDISGTLPTSVLVAPMGSSLQSFPLPPPPPPHAPDAFPRIA PIRAAESLHSQPPQHLQCPLYRPDSSSFAASLRELEKCGWYWGPMNWEDAEMKLKGKPDGSFLVRDSSDPRYILSLSFRSQGITHHTRME HYRGTFSLWCHPKFEDRCQSVVEFIKRAIMHSKNGKFLYFLRSRVPDELTVPRYRTEKPSKSPPPPPPRRSFPSSHGLTTTRTGEVVVTS KKDSAFIKKAESEELEVQKPQVKLRRAVSEVARPASTPPIMASAIKDEDDEDRIIAELESGGGSVPPMKVVTPGASRLKAAQGQAGSPDK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SOCS7_ENST00000331159_chr17_36533668_+_SRCIN1_ENST00000264659_chr17_36705446_-_1977nt ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGCATTTCCCCGGATTGCTCCCATCCGAGCA GCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCCAGCCTTCGAGAG TTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGTTCTTTCCTGGTA CGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAGCACTACAGAGGA ACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATGCACTCCAAGAAT GGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGCCCTCCAAGTCGCCCCCA CCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCACCAGCAAGAAGGACTCG GCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGTCTGAGGTGGCCCGCCCA GCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAGAGAGTGGCGGAGGCAGT GTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCGACAAAAGCAAACATGGC AAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGTCGAATGAGACCTCGAGC >In-frame_SOCS7_ENST00000331159_chr17_36533668_+_SRCIN1_ENST00000578925_chr17_36705446_-_1977nt ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGCATTTCCCCGGATTGCTCCCATCCGAGCA GCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCCAGCCTTCGAGAG TTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGTTCTTTCCTGGTA CGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAGCACTACAGAGGA ACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATGCACTCCAAGAAT GGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGCCCTCCAAGTCGCCCCCA CCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCACCAGCAAGAAGGACTCG GCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGTCTGAGGTGGCCCGCCCA GCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAGAGAGTGGCGGAGGCAGT GTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCGACAAAAGCAAACATGGC AAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGTCGAATGAGACCTCGAGC >In-frame_SOCS7_ENST00000577233_chr17_36533668_+_SRCIN1_ENST00000264659_chr17_36705446_-_2079nt ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCCTACATCTGTC CTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCT CCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCC AGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAG CACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATG CACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGCCCTCC AAGTCGCCCCCACCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCACCAGC AAGAAGGACTCGGCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGTCTGAG GTGGCCCGCCCAGCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAGAGAGT GGCGGAGGCAGTGTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCGACAAA AGCAAACATGGCAAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGTCGAAT GAGACCTCGAGCCCAGTCTCAGAAAAGCCCTCGGCTTCCAGAACCTCTATCCCTGTATTGACTTCCTTTGGGGCAAGGAATTCTTCCATC >In-frame_SOCS7_ENST00000577233_chr17_36533668_+_SRCIN1_ENST00000578925_chr17_36705446_-_2079nt ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCCTACATCTGTC CTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCT CCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCC AGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAG CACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATG CACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGCCCTCC AAGTCGCCCCCACCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCACCAGC AAGAAGGACTCGGCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGTCTGAG GTGGCCCGCCCAGCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAGAGAGT GGCGGAGGCAGTGTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCGACAAA AGCAAACATGGCAAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGTCGAAT GAGACCTCGAGCCCAGTCTCAGAAAAGCCCTCGGCTTCCAGAACCTCTATCCCTGTATTGACTTCCTTTGGGGCAAGGAATTCTTCCATC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SOCS7_ENST00000331159_chr17_36533668_+_SRCIN1_ENST00000264659_chr17_36705446_-_5275nt CCCGGCCGCCGCAGCTGATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGG AACTGCTGTGTCCCCGGCACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTG GACTAGAGGCGCAGTTGGCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGT GTCCTCCTCAGCCGCCCCCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGC TGGTCCTGGAGGGCTTGGAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAG GAGGGGGCGGCCGGCTTCTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCC TGAGTAGAGGGGAGCAGCAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTT CTCGGAAGGGCTCCTTCAAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCA AGAGGCCTTCTGGAGAGCTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAAC CCAAGTTGACAAGAACTCAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACA TTTCTCAGCGGGGCCTGACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGCATTTCCCCGGA TTGCTCCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTG CAGCCAGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAG ATGGTTCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAA TGGAGCACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCA TTATGCACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGC CCTCCAAGTCGCCCCCACCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCA CCAGCAAGAAGGACTCGGCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGT CTGAGGTGGCCCGCCCAGCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAG AGAGTGGCGGAGGCAGTGTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCG ACAAAAGCAAACATGGCAAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGT CGAATGAGACCTCGAGCCCAGTCTCAGAAAAGCCCTCGGCTTCCAGAACCTCTATCCCTGTATTGACTTCCTTTGGGGCAAGGAATTCTT CCATCTCCTTCTAGAAGCCCCTCACCCCGCTGCCCCGCCTGTCCCCCTCCCTCACTCCTGCCATTTCTCCCCTCTCTTCCTTCATCTCCA CCCCACCCCACCCTACTCTCCAGACGCCCTGAGGGGTGTGCCCTGAAGAGGAGGGTGCGGCCCTCCTCAGCGACCCCTACCCATCATCTG TTGGTGTTTTTGGTTTTGTTTTTTTTTTTTTTTTTAACAATTAACTTTTAATTATCTTTTTTTAAACAGTAAAACTAAAAACCAAACACA CCACCTTCCTTGATCCCAGCTGGCCTCTCGCTGGCCGCACCTGTCACATCTCTCCTTCTTCTCTTTCACCACTCTTTCCCCCAGTCCATC CTGAAGCTCCTGCACCCCCTTCCCGCCTTCCCCTCACTTCCCAAGAATACTCCAAACAAACTCTGAACCACGGAGACTTGGAGCAGTGGG AGACCCCTCTCCCGTTTCTCGATACCTTCCTGGAGGAACGCGGGGACATCGGACCAACCCATACATCAAGCCAGAGAGCGGGGCTTAGGG AGACTGGCCTTGGAGATGCCCCACTCCCTGTCTAAGCTCCGACAAGACTGTGACTTCCTCTGTGGCTGCTCTGCCTCCTCCCACTCACAC CCAAGTGGGCCTGGAGTAGAGACGGACAGGCTGGAGACGAGGCCGGAGTTTGAGAGGCCTCAGGGTGGGTGTGAGGCCATGGAGTCTGTA TCCCTGGGGAGGCGCTGGCCTCCTGGGCCTTGCCGTCCAGTGGGGAGTGGAGGGCAGAGGCCCTTTGGTCTGCTGGCTGTGGAGGGTGGG TTGCACGGACAGCCGGATATCGGGGACACTGCCTTGGGAGAGGGCGGCCCGGACGGGTATTTGGTACTTTTAGTTTCCTGATTTAGCACT TTAAATGGCATTAACTTATTGAATGGGGATGGGGTGGGCAAGAGTGAGGGGCCTAGAAAACCAGGTTTTGTGGCTTGCAGTTGGGGGAAG GGTCTGGTTTGAGGGAAATGGGAGGGTCGAGAGGGGCTTGACGGGGAGCACTGAAGACACCTGGGACCCGCAGGTGGGGTGACTTGAACT TCAGTCATCCTCTTGGCAATTTGAGGGTTTTCCCAGGAAAGGATGAGACGTAGTTTTTCAATGGGGCTCTGGTGACCCTGGTGAGATGTC TGAAGGTCCCTGAGGCCTGACCATCCAGCCAGCGCCCCTGGCCTGTGGACGCCCTGCCTGCCCTGCAGAGGCGGTTGGCAGTGCCGCCTG GCTTTTGGCCGGGTCCTGGGGAGGCAGAGAGAGGCCAATTTTGGTTCTCACTCCTGGCCCCCCAGAGGGCACAGTGAGGAGCCGGTAGGG AGAGGATAGGAGAAGAGGAGGAGGAGGAGCGGGGTCCCCGGCCGCAGGATTCCCACTTGGAGCACAAAGTGAAGTAAGCACAGGGGAGGG GGACTAGAATCAGTCCCCCATAGCAAGCACAGAAAGGAGGAGCTGCGCAGAAGGCAGAGCCCCCCAGACCCTGGGGCCTGGCTGGGGAAG GTCCGCACCTGGGGAGAGCTGGGAGCTGTTGAAGGTTTGGGGGGAGGGGAAACGGGTTGTGTTTCTTCATTTCTTTTTTTGTTTTTGCCT TTGTTGGTTCATCCTTGTTTTCTAGCTTTGGATCATTTTTGTACCAAGGCGAGCAAGCCTTTTTGAAAAATAACAAAAGAGGAAAAAAAA AATCCCTCCTGGAAAAAAAAAAAAACCCTGGAAAATAGAAAAAAAAAAAAGGACCTCATAAATGATGCAATTACTTTTAATTGCAGGCAA CTCTTTACATTTAAGTGAAGTGTCTTAACATTTTATATTGTTTTAAAAATATATTTACATATTATATATATAATATACGTAATATAAATA TATATAAATATTTAAAAAAGAAAAAAAAAAGAAAACCACGGCACTCTCCCTGGCCACTGTTTTGGCGGGGGAGGGGGGCTGGGGGGCGGG CACGTCGGCCTGGCTTCTGTGGTCCCAGTGAAATGGTCTGGTTTGATTTGGCTGTACAGAGACCCCCTGACTTGGGAGGGGAGGGGGGAG TGGTGCCCCCTCCTCCCTCCACTCCATTACTCTCTGCTTGCTACTTCGCTTGCCCCCAGCTCCCACCCTCAGCCCTGTGACTGGAATGTG TGCCCCACCGTCATTGTCCTGAGTTGAATGTCCCTTTGTGGGGGAGGTGGGGGGGGCAGTGTCCATCCACGAAGGGGCAGAAGGAGGGAG CCACGTGCCCCGCCCCACCCGCTCGGGTGAAGCCCAGTGGGATTTGCATCTTTCTTTCTCTTTGGTTCCTGCACATTTATGGGCTGGGAG GCATCCGTGTGGAATTGCGTGCAGCCTGTGTGTGTGCTGGCACAAGCCCATGCACTGTGTGTGCAGACGCATGGGGCCTGCACCCACAGG CATGGCCGAGCACATGTGTGGGGGAAGGCGTGGGCACATAGGTGCATGTAACCTGTTTGGGCATTGGCACGTGCCTACCTGCATGTTAGC GTGAGAGGAGCTTTGTGTGTGAGAACATGTGTAATGTGTGTGCAGACATGCCGAGAGCCAGAGACTTGTGTGTGGGCCACGTACATGTGG ATAGAGACGCATACATGGAGGTGCATGTAATCTGTGTCTCCGAGTGTGTGTGTGCAGGTATGTGTGCTGGTGCAGACCCAAGTGTGTGGG TGTGCCTCTGTGTGCGTGTGTTCCATCATCCCTGCACCACTGGCTCCAGATCCCTTCCTGAGCCCCCGTCCCCGCTGGCCCTCTCACAGC CTGCAGCACATCAGTGCCCCCAGCTGCATGCGCCTCGCTGCTCTGTCCATCAGTGTGTGCTTGACCAAGAGAAAACTAAGACGTCTCGGG GGACCCCTGTACCTGGTCCTCTCAGCCCCCGCCCACTGTGCTGTGTTACTCGCATGGGGGATTTCCTGCCCCTTCCACAATATGCTGTTT CCCCAGGAGCCTCAGGCCTGAGGCTCTGAGTGGGGTCCCCAGGGGGCCCCCCGGGGTGAGCCCCGGCTCCACACCCTGCCCCATCCACCC TGTAGGGCCCATGTTGGTGTAGCAGTGATGGCTTCTGTGGATATTCTGTGACCTCTGTCGGTGTAACTTGACAATTTCTAAATGGAAAAG GGTTGCTGTGTTTTCTCTGTCTCTCTTTTTTAATGTCCTTTTTTCTTCTCCCCCGCTCCCTGCTCTCTTTCCTTTTCAGTTTTTCTAGCC >In-frame_SOCS7_ENST00000331159_chr17_36533668_+_SRCIN1_ENST00000578925_chr17_36705446_-_2847nt CCCGGCCGCCGCAGCTGATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGG AACTGCTGTGTCCCCGGCACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTG GACTAGAGGCGCAGTTGGCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGT GTCCTCCTCAGCCGCCCCCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGC TGGTCCTGGAGGGCTTGGAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAG GAGGGGGCGGCCGGCTTCTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCC TGAGTAGAGGGGAGCAGCAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTT CTCGGAAGGGCTCCTTCAAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCA AGAGGCCTTCTGGAGAGCTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAAC CCAAGTTGACAAGAACTCAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACA TTTCTCAGCGGGGCCTGACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGCATTTCCCCGGA TTGCTCCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTG CAGCCAGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAG ATGGTTCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAA TGGAGCACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCA TTATGCACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGC CCTCCAAGTCGCCCCCACCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCA CCAGCAAGAAGGACTCGGCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGT CTGAGGTGGCCCGCCCAGCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAG AGAGTGGCGGAGGCAGTGTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCG ACAAAAGCAAACATGGCAAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGT CGAATGAGACCTCGAGCCCAGTCTCAGAAAAGCCCTCGGCTTCCAGAACCTCTATCCCTGTATTGACTTCCTTTGGGGCAAGGAATTCTT CCATCTCCTTCTAGAAGCCCCTCACCCCGCTGCCCCGCCTGTCCCCCTCCCTCACTCCTGCCATTTCTCCCCTCTCTTCCTTCATCTCCA CCCCACCCCACCCTACTCTCCAGACGCCCTGAGGGGTGTGCCCTGAAGAGGAGGGTGCGGCCCTCCTCAGCGACCCCTACCCATCATCTG TTGGTGTTTTTGGTTTTGTTTTTTTTTTTTTTTTTAACAATTAACTTTTAATTATCTTTTTTTAAACAGTAAAACTAAAAACCAAACACA CCACCTTCCTTGATCCCAGCTGGCCTCTCGCTGGCCGCACCTGTCACATCTCTCCTTCTTCTCTTTCACCACTCTTTCCCCCAGTCCATC CTGAAGCTCCTGCACCCCCTTCCCGCCTTCCCCTCACTTCCCAAGAATACTCCAAACAAACTCTGAACCACGGAGACTTGGAGCAGTGGG AGACCCCTCTCCCGTTTCTCGATACCTTCCTGGAGGAACGCGGGGACATCGGACCAACCCATACATCAAGCCAGAGAGCGGGGCTTAGGG AGACTGGCCTTGGAGATGCCCCACTCCCTGTCTAAGCTCCGACAAGACTGTGACTTCCTCTGTGGCTGCTCTGCCTCCTCCCACTCACAC CCAAGTGGGCCTGGAGTAGAGACGGACAGGCTGGAGACGAGGCCGGAGTTTGAGAGGCCTCAGGGTGGGTGTGAGGCCATGGAGTCTGTA TCCCTGGGGAGGCGCTGGCCTCCTGGGCCTTGCCGTCCAGTGGGGAGTGGAGGGCAGAGGCCCTTTGGTCTGCTGGCTGTGGAGGGTGGG >In-frame_SOCS7_ENST00000577233_chr17_36533668_+_SRCIN1_ENST00000264659_chr17_36705446_-_5360nt ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCCTACATCTGTC CTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCT CCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCC AGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAG CACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATG CACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGCCCTCC AAGTCGCCCCCACCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCACCAGC AAGAAGGACTCGGCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGTCTGAG GTGGCCCGCCCAGCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAGAGAGT GGCGGAGGCAGTGTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCGACAAA AGCAAACATGGCAAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGTCGAAT GAGACCTCGAGCCCAGTCTCAGAAAAGCCCTCGGCTTCCAGAACCTCTATCCCTGTATTGACTTCCTTTGGGGCAAGGAATTCTTCCATC TCCTTCTAGAAGCCCCTCACCCCGCTGCCCCGCCTGTCCCCCTCCCTCACTCCTGCCATTTCTCCCCTCTCTTCCTTCATCTCCACCCCA CCCCACCCTACTCTCCAGACGCCCTGAGGGGTGTGCCCTGAAGAGGAGGGTGCGGCCCTCCTCAGCGACCCCTACCCATCATCTGTTGGT GTTTTTGGTTTTGTTTTTTTTTTTTTTTTTAACAATTAACTTTTAATTATCTTTTTTTAAACAGTAAAACTAAAAACCAAACACACCACC TTCCTTGATCCCAGCTGGCCTCTCGCTGGCCGCACCTGTCACATCTCTCCTTCTTCTCTTTCACCACTCTTTCCCCCAGTCCATCCTGAA GCTCCTGCACCCCCTTCCCGCCTTCCCCTCACTTCCCAAGAATACTCCAAACAAACTCTGAACCACGGAGACTTGGAGCAGTGGGAGACC CCTCTCCCGTTTCTCGATACCTTCCTGGAGGAACGCGGGGACATCGGACCAACCCATACATCAAGCCAGAGAGCGGGGCTTAGGGAGACT GGCCTTGGAGATGCCCCACTCCCTGTCTAAGCTCCGACAAGACTGTGACTTCCTCTGTGGCTGCTCTGCCTCCTCCCACTCACACCCAAG TGGGCCTGGAGTAGAGACGGACAGGCTGGAGACGAGGCCGGAGTTTGAGAGGCCTCAGGGTGGGTGTGAGGCCATGGAGTCTGTATCCCT GGGGAGGCGCTGGCCTCCTGGGCCTTGCCGTCCAGTGGGGAGTGGAGGGCAGAGGCCCTTTGGTCTGCTGGCTGTGGAGGGTGGGTTGCA CGGACAGCCGGATATCGGGGACACTGCCTTGGGAGAGGGCGGCCCGGACGGGTATTTGGTACTTTTAGTTTCCTGATTTAGCACTTTAAA TGGCATTAACTTATTGAATGGGGATGGGGTGGGCAAGAGTGAGGGGCCTAGAAAACCAGGTTTTGTGGCTTGCAGTTGGGGGAAGGGTCT GGTTTGAGGGAAATGGGAGGGTCGAGAGGGGCTTGACGGGGAGCACTGAAGACACCTGGGACCCGCAGGTGGGGTGACTTGAACTTCAGT CATCCTCTTGGCAATTTGAGGGTTTTCCCAGGAAAGGATGAGACGTAGTTTTTCAATGGGGCTCTGGTGACCCTGGTGAGATGTCTGAAG GTCCCTGAGGCCTGACCATCCAGCCAGCGCCCCTGGCCTGTGGACGCCCTGCCTGCCCTGCAGAGGCGGTTGGCAGTGCCGCCTGGCTTT TGGCCGGGTCCTGGGGAGGCAGAGAGAGGCCAATTTTGGTTCTCACTCCTGGCCCCCCAGAGGGCACAGTGAGGAGCCGGTAGGGAGAGG ATAGGAGAAGAGGAGGAGGAGGAGCGGGGTCCCCGGCCGCAGGATTCCCACTTGGAGCACAAAGTGAAGTAAGCACAGGGGAGGGGGACT AGAATCAGTCCCCCATAGCAAGCACAGAAAGGAGGAGCTGCGCAGAAGGCAGAGCCCCCCAGACCCTGGGGCCTGGCTGGGGAAGGTCCG CACCTGGGGAGAGCTGGGAGCTGTTGAAGGTTTGGGGGGAGGGGAAACGGGTTGTGTTTCTTCATTTCTTTTTTTGTTTTTGCCTTTGTT GGTTCATCCTTGTTTTCTAGCTTTGGATCATTTTTGTACCAAGGCGAGCAAGCCTTTTTGAAAAATAACAAAAGAGGAAAAAAAAAATCC CTCCTGGAAAAAAAAAAAAACCCTGGAAAATAGAAAAAAAAAAAAGGACCTCATAAATGATGCAATTACTTTTAATTGCAGGCAACTCTT TACATTTAAGTGAAGTGTCTTAACATTTTATATTGTTTTAAAAATATATTTACATATTATATATATAATATACGTAATATAAATATATAT AAATATTTAAAAAAGAAAAAAAAAAGAAAACCACGGCACTCTCCCTGGCCACTGTTTTGGCGGGGGAGGGGGGCTGGGGGGCGGGCACGT CGGCCTGGCTTCTGTGGTCCCAGTGAAATGGTCTGGTTTGATTTGGCTGTACAGAGACCCCCTGACTTGGGAGGGGAGGGGGGAGTGGTG CCCCCTCCTCCCTCCACTCCATTACTCTCTGCTTGCTACTTCGCTTGCCCCCAGCTCCCACCCTCAGCCCTGTGACTGGAATGTGTGCCC CACCGTCATTGTCCTGAGTTGAATGTCCCTTTGTGGGGGAGGTGGGGGGGGCAGTGTCCATCCACGAAGGGGCAGAAGGAGGGAGCCACG TGCCCCGCCCCACCCGCTCGGGTGAAGCCCAGTGGGATTTGCATCTTTCTTTCTCTTTGGTTCCTGCACATTTATGGGCTGGGAGGCATC CGTGTGGAATTGCGTGCAGCCTGTGTGTGTGCTGGCACAAGCCCATGCACTGTGTGTGCAGACGCATGGGGCCTGCACCCACAGGCATGG CCGAGCACATGTGTGGGGGAAGGCGTGGGCACATAGGTGCATGTAACCTGTTTGGGCATTGGCACGTGCCTACCTGCATGTTAGCGTGAG AGGAGCTTTGTGTGTGAGAACATGTGTAATGTGTGTGCAGACATGCCGAGAGCCAGAGACTTGTGTGTGGGCCACGTACATGTGGATAGA GACGCATACATGGAGGTGCATGTAATCTGTGTCTCCGAGTGTGTGTGTGCAGGTATGTGTGCTGGTGCAGACCCAAGTGTGTGGGTGTGC CTCTGTGTGCGTGTGTTCCATCATCCCTGCACCACTGGCTCCAGATCCCTTCCTGAGCCCCCGTCCCCGCTGGCCCTCTCACAGCCTGCA GCACATCAGTGCCCCCAGCTGCATGCGCCTCGCTGCTCTGTCCATCAGTGTGTGCTTGACCAAGAGAAAACTAAGACGTCTCGGGGGACC CCTGTACCTGGTCCTCTCAGCCCCCGCCCACTGTGCTGTGTTACTCGCATGGGGGATTTCCTGCCCCTTCCACAATATGCTGTTTCCCCA GGAGCCTCAGGCCTGAGGCTCTGAGTGGGGTCCCCAGGGGGCCCCCCGGGGTGAGCCCCGGCTCCACACCCTGCCCCATCCACCCTGTAG GGCCCATGTTGGTGTAGCAGTGATGGCTTCTGTGGATATTCTGTGACCTCTGTCGGTGTAACTTGACAATTTCTAAATGGAAAAGGGTTG CTGTGTTTTCTCTGTCTCTCTTTTTTAATGTCCTTTTTTCTTCTCCCCCGCTCCCTGCTCTCTTTCCTTTTCAGTTTTTCTAGCCAAGTG >In-frame_SOCS7_ENST00000577233_chr17_36533668_+_SRCIN1_ENST00000578925_chr17_36705446_-_2932nt ATGGTGTTCCGCAACGTGGGTCGGCCGCCGGAGGAGGAGGACGTGGAGGCGGCCCCGGAGCCGGGACCCTCGGAACTGCTGTGTCCCCGG CACCGCTGTGCCCTGGACCCCAAGGCCCTGCCGCCGGGCTTGGCGCTCGAGCGGACCTGGGGCCCGGCGGCTGGACTAGAGGCGCAGTTG GCGGCTCTGGGGCTCGGGCAGCCGGCGGGGCCGGGGGTCAAGACAGTCGGTGGGGGTTGCTGCCCGTGTCCGTGTCCTCCTCAGCCGCCC CCTCCGCAGCCCCAGCCGCCTGCTGCCGCCCCGCAGGCCGGGGAGGACCCCACGGAAACGAGCGACGCGCTGCTGGTCCTGGAGGGCTTG GAATCGGAGGCCGAGAGCCTGGAGACTAACAGCTGCTCGGAAGAGGAGCTCAGCAGCCCGGGTCGCGGAGGAGGAGGGGGCGGCCGGCTT CTGCTGCAGCCCCCAGGCCCTGAATTACCTCCGGTGCCCTTCCCGCTGCAGGACTTGGTCCCTCTGGGGCGCCTGAGTAGAGGGGAGCAG CAGCAGCAGCAGCAGCAGCAACCTCCCCCGCCCCCGCCTCCTCCCGGGCCCCTCCGGCCACTCGCGGGTCCTTCTCGGAAGGGCTCCTTC AAAATCCGCCTCAGTCGCCTCTTTCGCACCAAGAGCTGCAACGGTGGCTCCGGCGGTGGGGATGGGACCGGCAAGAGGCCTTCTGGAGAG CTGGCTGCTTCAGCTGCGAGCCTGACAGACATGGGAGGCTCTGCGGGCCGGGAGCTGGACGCGGGGAGGAAACCCAAGTTGACAAGAACT CAAAGTGCCTTTTCTCCGGTCTCCTTCAGCCCCCTGTTCACAGGTGAAACTGTGTCGCTTGTGGATGTGGACATTTCTCAGCGGGGCCTG ACCTCTCCACACCCTCCAACTCCCCCTCCTCCTCCGAGAAGAAGCCTCAGCCTCCTAGATGATATCAGTGGGACGCTGCCTACATCTGTC CTTGTGGCTCCGATGGGGTCTTCCTTGCAGTCTTTCCCCCTACCTCCGCCTCCTCCACCCCATGCCCCAGATGCATTTCCCCGGATTGCT CCCATCCGAGCAGCTGAATCCCTGCACAGCCAACCCCCACAGCACCTCCAGTGTCCCCTCTACCGGCCTGACTCGAGCAGCTTTGCAGCC AGCCTTCGAGAGTTGGAGAAGTGTGGTTGGTATTGGGGGCCAATGAATTGGGAAGATGCAGAGATGAAGCTGAAAGGGAAACCAGATGGT TCTTTCCTGGTACGAGACAGTTCTGATCCTCGTTACATCCTGAGCCTCAGTTTCCGATCACAGGGTATCACCCACCACACTAGAATGGAG CACTACAGAGGAACCTTCAGCCTGTGGTGTCATCCCAAGTTTGAGGACCGCTGTCAATCTGTTGTAGAGTTTATTAAGAGAGCCATTATG CACTCCAAGAATGGAAAGTTTCTCTATTTCTTAAGATCCAGGGTTCCAGATGAGTTGACCGTGCCCCGATACCGCACAGAGAAGCCCTCC AAGTCGCCCCCACCGCCCCCTCCCCGCCGGAGCTTCCCCTCCTCCCATGGCCTGACCACCACACGTACCGGAGAGGTGGTGGTCACCAGC AAGAAGGACTCGGCCTTCATCAAGAAGGCTGAGTCCGAGGAGCTGGAGGTGCAGAAGCCCCAGGTGAAGCTGCGCCGGGCTGTGTCTGAG GTGGCCCGCCCAGCCTCCACACCACCCATCATGGCCTCGGCCATCAAGGACGAGGATGACGAGGATCGCATCATCGCAGAGCTAGAGAGT GGCGGAGGCAGTGTACCACCCATGAAGGTGGTGACTCCGGGGGCCTCTCGGCTGAAGGCGGCCCAGGGCCAGGCGGGCAGCCCCGACAAA AGCAAACATGGCAAGCAGAGGGCCGAGTACATGCGGATCCAGGCCCAGCAGCAGGCCACTAAACCATCTAAAGAGATGAGCGGGTCGAAT GAGACCTCGAGCCCAGTCTCAGAAAAGCCCTCGGCTTCCAGAACCTCTATCCCTGTATTGACTTCCTTTGGGGCAAGGAATTCTTCCATC TCCTTCTAGAAGCCCCTCACCCCGCTGCCCCGCCTGTCCCCCTCCCTCACTCCTGCCATTTCTCCCCTCTCTTCCTTCATCTCCACCCCA CCCCACCCTACTCTCCAGACGCCCTGAGGGGTGTGCCCTGAAGAGGAGGGTGCGGCCCTCCTCAGCGACCCCTACCCATCATCTGTTGGT GTTTTTGGTTTTGTTTTTTTTTTTTTTTTTAACAATTAACTTTTAATTATCTTTTTTTAAACAGTAAAACTAAAAACCAAACACACCACC TTCCTTGATCCCAGCTGGCCTCTCGCTGGCCGCACCTGTCACATCTCTCCTTCTTCTCTTTCACCACTCTTTCCCCCAGTCCATCCTGAA GCTCCTGCACCCCCTTCCCGCCTTCCCCTCACTTCCCAAGAATACTCCAAACAAACTCTGAACCACGGAGACTTGGAGCAGTGGGAGACC CCTCTCCCGTTTCTCGATACCTTCCTGGAGGAACGCGGGGACATCGGACCAACCCATACATCAAGCCAGAGAGCGGGGCTTAGGGAGACT GGCCTTGGAGATGCCCCACTCCCTGTCTAAGCTCCGACAAGACTGTGACTTCCTCTGTGGCTGCTCTGCCTCCTCCCACTCACACCCAAG TGGGCCTGGAGTAGAGACGGACAGGCTGGAGACGAGGCCGGAGTTTGAGAGGCCTCAGGGTGGGTGTGAGGCCATGGAGTCTGTATCCCT GGGGAGGCGCTGGCCTCCTGGGCCTTGCCGTCCAGTGGGGAGTGGAGGGCAGAGGCCCTTTGGTCTGCTGGCTGTGGAGGGTGGGTTGCA |
Top |
FusionGenePPI for SOCS7_SRCIN1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SOCS7 | NCK1, CUL5, SORBS3, STAT3, STAT5A, SEPT6, DAB1 | SRCIN1 | BCAR1, CRK, SNAP25, SRC, CSK, SORBS3, SYP, NUFIP1, BCAS4, CKAP5, CDH1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | SRCIN1 | chr17:36533668 | chr17:36705446 | ENST00000264659 | - | 14 | 19 | 647_697 | 987 | 1184 | SNAP25 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SOCS7_SRCIN1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SOCS7_SRCIN1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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