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Fusion gene ID: 35322 |
FusionGeneSummary for SNX6_ADAMTS12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SNX6_ADAMTS12 | Fusion gene ID: 35322 | Hgene | Tgene | Gene symbol | SNX6 | ADAMTS12 | Gene ID | 58533 | 81792 |
| Gene name | sorting nexin 6 | ADAM metallopeptidase with thrombospondin type 1 motif 12 | |
| Synonyms | MSTP010|TFAF2 | PRO4389 | |
| Cytomap | 14q13.1 | 5p13.3-p13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sorting nexin-6TRAF4-associated factor 2tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2 | A disintegrin and metalloproteinase with thrombospondin motifs 12ADAM-TS 12ADAM-TS12ADAMTS-12a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q9UNH7 | P58397 | |
| Ensembl transtripts involved in fusion gene | ENST00000396526, ENST00000396534, ENST00000362031, ENST00000355110, | ENST00000504830, ENST00000352040, ENST00000504582, ENST00000515401, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 7 X 4 X 5=140 |
| # samples | 6 | 7 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/140*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SNX6 [Title/Abstract] AND ADAMTS12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SNX6 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway | 11279102 |
| Hgene | SNX6 | GO:0045892 | negative regulation of transcription, DNA-templated | 11279102|20830743 |
| Tgene | ADAMTS12 | GO:0030167 | proteoglycan catabolic process | 17895370 |
| Tgene | ADAMTS12 | GO:0032331 | negative regulation of chondrocyte differentiation | 22247065 |
| Tgene | ADAMTS12 | GO:0050727 | regulation of inflammatory response | 23019333 |
| Tgene | ADAMTS12 | GO:0051603 | proteolysis involved in cellular protein catabolic process | 16611630 |
| Tgene | ADAMTS12 | GO:0071773 | cellular response to BMP stimulus | 22247065 |
| Tgene | ADAMTS12 | GO:1901509 | regulation of endothelial tube morphogenesis | 17895370 |
| Tgene | ADAMTS12 | GO:1902203 | negative regulation of hepatocyte growth factor receptor signaling pathway | 17895370 |
| Tgene | ADAMTS12 | GO:1902548 | negative regulation of cellular response to vascular endothelial growth factor stimulus | 17895370 |
| Tgene | ADAMTS12 | GO:2001113 | negative regulation of cellular response to hepatocyte growth factor stimulus | 17895370 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | COAD | TCGA-CM-6172-01A | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000396526 | ENST00000504830 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-3CDS | ENST00000396526 | ENST00000352040 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-5UTR | ENST00000396526 | ENST00000504582 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-5UTR | ENST00000396526 | ENST00000515401 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-3CDS | ENST00000396534 | ENST00000504830 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-3CDS | ENST00000396534 | ENST00000352040 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-5UTR | ENST00000396534 | ENST00000504582 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-5UTR | ENST00000396534 | ENST00000515401 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| In-frame | ENST00000362031 | ENST00000504830 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| In-frame | ENST00000362031 | ENST00000352040 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5CDS-5UTR | ENST00000362031 | ENST00000504582 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5CDS-5UTR | ENST00000362031 | ENST00000515401 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-3CDS | ENST00000355110 | ENST00000504830 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-3CDS | ENST00000355110 | ENST00000352040 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-5UTR | ENST00000355110 | ENST00000504582 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
| 5UTR-5UTR | ENST00000355110 | ENST00000515401 | SNX6 | chr14 | 35099113 | - | ADAMTS12 | chr5 | 33751653 | - |
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FusionProtFeatures for SNX6_ADAMTS12 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SNX6 | ADAMTS12 |
| Involved in several stages of intracellular trafficking.Interacts with membranes phosphatidylinositol 3,4-bisphosphateand/or phosphatidylinositol 4,5-bisphosphate (Probable). Acts inpart as component of the retromer membrane-deforming SNX-BARsubcomplex (PubMed:19935774). The SNX-BAR retromer mediatesretrograde transport of cargo proteins from endosomes to thetrans-Golgi network (TGN) and is involved in endosome-to-plasmamembrane transport for cargo protein recycling. The SNX-BARsubcomplex functions to deform the donor membrane into a tubularprofile called endosome-to-TGN transport carrier (ETC) (Probable).Does not have in vitro vesicle-to-membrane remodeling activity(PubMed:23085988). Involved in retrograde endosome-to-TGNtransport of lysosomal enzyme receptor IGF2R (PubMed:17148574).May function as link between transport vesicles and dynactin(Probable). Negatively regulates retrograde transport of BACE1from the cell surface to the trans-Golgi network(PubMed:20354142). Involved in E-cadherin sorting and degradation;inhibits PIP5K1C isoform 3-mediated E-cadherin degradation(PubMed:24610942). In association with GIT1 involved in EGFRdegradation. Promotes lysosomal degradation of CDKN1B (Bysimilarity). May contribute to transcription regulation(Probable). {ECO:0000250|UniProtKB:Q6P8X1,ECO:0000269|PubMed:17148574, ECO:0000269|PubMed:19935774,ECO:0000269|PubMed:20354142, ECO:0000269|PubMed:23085988,ECO:0000269|PubMed:24610942, ECO:0000303|PubMed:19935774,ECO:0000303|PubMed:20830743, ECO:0000305}. | Metalloprotease that may play a role in the degradationof COMP. Cleaves also alpha-2 macroglobulin and aggregan. Hasanti-tumorigenic properties. {ECO:0000269|PubMed:16611630,ECO:0000269|PubMed:17895370, ECO:0000269|PubMed:18485748}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for SNX6_ADAMTS12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SNX6_ENST00000362031_chr14_35099113_-_ADAMTS12_ENST00000504830_chr5_33751653_-_1462aa MRACAGPRLGAAMMEGLDDGPDFLSEEDRGTGFFQLPHGDFFIEPVKKHPLVEGGYHPHIVYRRQKVPETKEPTCGLKDSVNISQKQELW REKWERHNLPSRSLSRRSISKERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHH AEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHD GKENDCEPVGRHPYIMSRQLQYDPTPLTWSKCSEEYITRFLDRGWGFCLDDIPKKKGLKSKVIAPGVIYDVHHQCQLQYGPNATFCQEVE NVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTG ERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFPIFNPAHPCELYCRPIDGQFSEKMLDAVIDGTPCFEGGNSRNVCINGIC KMVGCDYEIDSNATEDRCGVCLGDGSSCQTVRKMFKQKEGSGYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNG NYKLAGTVFQYDRKGDLEKLMATGPTNESVWIQLLFQVTNPGIKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHCIK KGRGMVKATFCDPETQPNGRQKKCHEKACPPRWWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDIL CPSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDVTRKPNSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLT TPTGPESMSTSTPAISSPSPTTASKEGDLGGKQWQDSSTQPELSSRYLISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGGLVATT TSGSGLSSSRNPITWPVTPFYNTLTKGPEMEIHSGSGEEREQPEDKDESNPVIWTKIRVPGNDAPVESTEMPLAPPLTPDLSRESWWPPF STVMEGLLPSQRPTTSETGTPRVEGMVTEKPANTLLPLGGDHQPEPSGKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGFLLNAS NYKQLTNGHGSAHWIVGNWSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFKIREIQCVD SRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATGNWDLC STSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQACKKSADLLCTKDKLSASFCQTLKAMKKCSVPTVRAECCFSCPQ >In-frame_SNX6_ENST00000362031_chr14_35099113_-_ADAMTS12_ENST00000352040_chr5_33751653_-_1377aa MRACAGPRLGAAMMEGLDDGPDFLSEEDRGTGFFQLPHGDFFIEPVKKHPLVEGGYHPHIVYRRQKVPETKEPTCGLKDSVNISQKQELW REKWERHNLPSRSLSRRSISKERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHH AEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHD GKENDCEPVGRHPYIMSRQLQYDPTPLTWSKCSEEYITRFLDRGWGFCLDDIPKKKGLKSKVIAPGVIYDVHHQCQLQYGPNATFCQEVE NVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTG ERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFPIFNPGYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFI IQWNGNYKLAGTVFQYDRKGDLEKLMATGPTNESVWIQLLFQVTNPGIKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQT AHCIKKGRGMVKATFCDPETQPNGRQKKCHEKACPPRWWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSC NRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDVTRKPNSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSR PRMLTTPTGPESMSTSTPAISSPSPTTASKEGDLGGKQWQDSSTQPELSSRYLISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGG LVATTTSGSGLSSSRNPITWPVTPFYNTLTKGPEMEIHSGSGEEREQPEDKDESNPVIWTKIRVPGNDAPVESTEMPLAPPLTPDLSRES WWPPFSTVMEGLLPSQRPTTSETGTPRVEGMVTEKPANTLLPLGGDHQPEPSGKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGF LLNASNYKQLTNGHGSAHWIVGNWSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFKIRE IQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATG NWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQACKKSADLLCTKDKLSASFCQTLKAMKKCSVPTVRAECC |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SNX6_ENST00000362031_chr14_35099113_-_ADAMTS12_ENST00000504830_chr5_33751653_-_4386nt ATGCGCGCCTGCGCCGGCCCTCGCCTCGGAGCAGCCATGATGGAAGGCCTGGACGACGGCCCGGACTTCCTCTCAGAAGAGGACCGCGGA ACTGGATTTTTCCAACTACCACATGGAGACTTTTTCATTGAACCCGTGAAGAAGCATCCACTGGTTGAGGGAGGGTACCACCCGCACATC GTTTACAGGAGGCAGAAAGTTCCAGAAACCAAGGAGCCAACCTGTGGATTAAAGGACAGTGTTAACATCTCCCAGAAGCAAGAGCTATGG CGGGAGAAGTGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAGCAAGGAGAGATGGGTGGAGACACTGGTGGTG GCCGACACAAAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCACCATCATGAACATGGTCACTGGGTTGTTCCAT AACCCAAGCATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGAAGAAGAGCAAGGACTGAAAATAGTTCACCAT GCAGAAAAGACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGACCTCAATCCTGTTCATCACGACGTGGCTGTC CTTCTCACCAGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCTGTCTCACCTTTCAGGAATGTGTCAGCCTCAC CGCAGTTGTAACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGAGCTAGGACACAGCTTCGGCATCCAGCATGAT GGGAAAGAAAATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCTCCAGTACGATCCCACTCCGCTGACATGGTCC AAGTGCAGCGAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGATGACATACCTAAAAAGAAAGGCTTGAAGTCC AAGGTCATTGCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGGACCCAATGCTACCTTCTGCCAGGAAGTAGAA AACGTCTGCCAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGCTGCTGCAGATGGAACTCAATGTGGTGAGAAG AAGTGGTGTATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGGAGGCTGGGGCCGCTGGTCACCCTGGTCCCAC TGTTCCAGGACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGAGCCAAAGTTTGGAGGGAAATATTGCACTGGA GAAAGAAAACGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATTTCGGCAGATGCAGTGCAGTGAATTTGACACT GTTCCCTACAAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGCACATCCTTGTGAGCTCTACTGCCGACCCATAGATGGCCAG TTTTCTGAGAAAATGCTGGATGCTGTCATTGATGGTACCCCTTGCTTTGAAGGCGGCAACAGCAGAAATGTCTGTATTAATGGCATATGT AAGATGGTTGGCTGTGACTATGAGATCGATTCCAATGCCACCGAGGATCGCTGCGGTGTGTGCCTGGGAGATGGCTCTTCCTGCCAGACT GTGAGAAAGATGTTTAAGCAGAAGGAAGGATCTGGTTATGTTGACATTGGGCTCATTCCAAAAGGAGCAAGGGACATAAGAGTGATGGAA ATTGAGGGAGCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCCTGAAAAATATTACCTGAATGGAGGGTTTATTATCCAGTGGAACGGG AACTATAAGCTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGGAGACCTGGAAAAGCTGATGGCCACAGGTCCCACCAATGAGTCTGTG TGGATCCAGCTTCTATTCCAGGTGACTAACCCTGGCATCAAGTATGAGTACACAATCCAGAAAGATGGCCTTGACAATGATGTTGAGCAG CAGATGTACTTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGTGACCTGCGGGACAGGTATCCGCCGCCAAACTGCCCATTGCATAAAG AAGGGCCGCGGGATGGTGAAAGCTACATTCTGTGACCCAGAAACACAGCCCAATGGGAGACAGAAGAAGTGCCATGAAAAGGCTTGTCCA CCCAGGTGGTGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATGCGGGCCCCACGGGGAGAAGAAGCGAACCGTGCTGTGCATCCAGACC ATGGTCTCTGACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCACCTGCTGAAGCCCAAGACCCTCCTTTCCTGCAACAGAGACATCCTG TGCCCCTCGGACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGTTTCCTGTGGTGGTGGAGTGCGGATTCGCAGTGTCACATGTGCCAAG AACCATGATGAACCTTGCGATGTGACAAGGAAACCCAACAGCCGAGCTCTGTGTGGCCTCCAGCAATGCCCTTCTAGCCGGAGAGTTCTG AAACCAAACAAAGGCACTATTTCCAATGGAAAAAACCCACCAACACTAAAGCCCGTCCCTCCACCTACATCCAGGCCCAGAATGCTGACC ACACCCACAGGGCCTGAGTCTATGAGCACAAGCACTCCAGCAATCAGCAGCCCTAGTCCTACCACAGCCTCCAAAGAAGGAGACCTGGGT GGGAAACAGTGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTCTCGCTATCTCATTTCCACTGGAAGCACTTCCCAGCCCATCCTCACT TCCCAATCCTTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAGTTCAGATACTGGTCCTACCTCGGAGGGAGGCCTTGTAGCTACAACA ACAAGTGGTTCTGGCTTGTCATCTTCCCGCAACCCTATCACTTGGCCTGTGACTCCATTTTACAATACCTTGACCAAAGGTCCAGAAATG GAGATTCACAGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGACAAAGATGAAAGCAATCCTGTAATATGGACCAAGATCAGAGTACCT GGAAATGACGCTCCAGTGGAAAGTACAGAAATGCCACTTGCACCTCCACTAACACCAGATCTCAGCAGGGAGTCCTGGTGGCCACCCTTC AGCACAGTAATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTACTTCCGAAACTGGGACACCCAGAGTTGAGGGGATGGTTACTGAAAAG CCAGCCAACACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGAACCCTCAGGAAAGACGGCAAACCGTAACCACCTGAAACTTCCAAAC AACATGAACCAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGAGGATGCAACAAGTCTGATTACTGAGGGCTTTTTGCTAAATGCCTCC AATTACAAGCAGCTCACAAACGGCCACGGCTCTGCACACTGGATCGTCGGAAACTGGAGCGAGTGCTCCACCACATGTGGCCTGGGGGCC TACTGGAGAAGGGTGGAGTGCAGCACCCAGATGGATTCTGACTGTGCGGCCATCCAGAGACCTGACCCTGCAAAAAGATGCCACCTCCGT CCCTGTGCTGGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAGAAACTGCAGTGGGGGCTTCAAGATACGCGAGATTCAGTGCGTGGAC AGCCGGGACCACCGGAACCTGAGGCCATTTCACTGCCAGTTCCTGGCCGGCATTCCTCCCCCATTGAGCATGAGCTGTAACCCGGAGCCC TGTGAGGCGTGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTCCTGTGGAGGTGGAGTTCAGGAGAGAGGAGTGTTCTGTCCAGGAGGC CTCTGTGATTGGACAAAAAGACCCACATCCACCATGTCTTGCAATGAGCACCTGTGCTGTCACTGGGCCACTGGGAACTGGGACCTGTGT TCCACTTCCTGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATGTGTGCCCTCAGAGGGCAATAAAACTGAAGACCAAGACCAATGTCTA TGTGATCACAAACCCAGACCTCCAGAATTCAAAAAATGCAACCAGCAGGCCTGCAAGAAAAGTGCCGATTTACTTTGCACTAAGGACAAA CTGTCAGCCAGTTTCTGCCAGACACTGAAAGCCATGAAGAAATGTTCTGTGCCCACCGTGAGGGCTGAGTGCTGCTTCTCGTGTCCCCAG >In-frame_SNX6_ENST00000362031_chr14_35099113_-_ADAMTS12_ENST00000352040_chr5_33751653_-_4131nt ATGCGCGCCTGCGCCGGCCCTCGCCTCGGAGCAGCCATGATGGAAGGCCTGGACGACGGCCCGGACTTCCTCTCAGAAGAGGACCGCGGA ACTGGATTTTTCCAACTACCACATGGAGACTTTTTCATTGAACCCGTGAAGAAGCATCCACTGGTTGAGGGAGGGTACCACCCGCACATC GTTTACAGGAGGCAGAAAGTTCCAGAAACCAAGGAGCCAACCTGTGGATTAAAGGACAGTGTTAACATCTCCCAGAAGCAAGAGCTATGG CGGGAGAAGTGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAGCAAGGAGAGATGGGTGGAGACACTGGTGGTG GCCGACACAAAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCACCATCATGAACATGGTCACTGGGTTGTTCCAT AACCCAAGCATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGAAGAAGAGCAAGGACTGAAAATAGTTCACCAT GCAGAAAAGACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGACCTCAATCCTGTTCATCACGACGTGGCTGTC CTTCTCACCAGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCTGTCTCACCTTTCAGGAATGTGTCAGCCTCAC CGCAGTTGTAACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGAGCTAGGACACAGCTTCGGCATCCAGCATGAT GGGAAAGAAAATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCTCCAGTACGATCCCACTCCGCTGACATGGTCC AAGTGCAGCGAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGATGACATACCTAAAAAGAAAGGCTTGAAGTCC AAGGTCATTGCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGGACCCAATGCTACCTTCTGCCAGGAAGTAGAA AACGTCTGCCAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGCTGCTGCAGATGGAACTCAATGTGGTGAGAAG AAGTGGTGTATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGGAGGCTGGGGCCGCTGGTCACCCTGGTCCCAC TGTTCCAGGACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGAGCCAAAGTTTGGAGGGAAATATTGCACTGGA GAAAGAAAACGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATTTCGGCAGATGCAGTGCAGTGAATTTGACACT GTTCCCTACAAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGGTTATGTTGACATTGGGCTCATTCCAAAAGGAGCAAGGGAC ATAAGAGTGATGGAAATTGAGGGAGCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCCTGAAAAATATTACCTGAATGGAGGGTTTATT ATCCAGTGGAACGGGAACTATAAGCTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGGAGACCTGGAAAAGCTGATGGCCACAGGTCCC ACCAATGAGTCTGTGTGGATCCAGCTTCTATTCCAGGTGACTAACCCTGGCATCAAGTATGAGTACACAATCCAGAAAGATGGCCTTGAC AATGATGTTGAGCAGCAGATGTACTTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGTGACCTGCGGGACAGGTATCCGCCGCCAAACT GCCCATTGCATAAAGAAGGGCCGCGGGATGGTGAAAGCTACATTCTGTGACCCAGAAACACAGCCCAATGGGAGACAGAAGAAGTGCCAT GAAAAGGCTTGTCCACCCAGGTGGTGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATGCGGGCCCCACGGGGAGAAGAAGCGAACCGTG CTGTGCATCCAGACCATGGTCTCTGACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCACCTGCTGAAGCCCAAGACCCTCCTTTCCTGC AACAGAGACATCCTGTGCCCCTCGGACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGTTTCCTGTGGTGGTGGAGTGCGGATTCGCAGT GTCACATGTGCCAAGAACCATGATGAACCTTGCGATGTGACAAGGAAACCCAACAGCCGAGCTCTGTGTGGCCTCCAGCAATGCCCTTCT AGCCGGAGAGTTCTGAAACCAAACAAAGGCACTATTTCCAATGGAAAAAACCCACCAACACTAAAGCCCGTCCCTCCACCTACATCCAGG CCCAGAATGCTGACCACACCCACAGGGCCTGAGTCTATGAGCACAAGCACTCCAGCAATCAGCAGCCCTAGTCCTACCACAGCCTCCAAA GAAGGAGACCTGGGTGGGAAACAGTGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTCTCGCTATCTCATTTCCACTGGAAGCACTTCC CAGCCCATCCTCACTTCCCAATCCTTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAGTTCAGATACTGGTCCTACCTCGGAGGGAGGC CTTGTAGCTACAACAACAAGTGGTTCTGGCTTGTCATCTTCCCGCAACCCTATCACTTGGCCTGTGACTCCATTTTACAATACCTTGACC AAAGGTCCAGAAATGGAGATTCACAGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGACAAAGATGAAAGCAATCCTGTAATATGGACC AAGATCAGAGTACCTGGAAATGACGCTCCAGTGGAAAGTACAGAAATGCCACTTGCACCTCCACTAACACCAGATCTCAGCAGGGAGTCC TGGTGGCCACCCTTCAGCACAGTAATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTACTTCCGAAACTGGGACACCCAGAGTTGAGGGG ATGGTTACTGAAAAGCCAGCCAACACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGAACCCTCAGGAAAGACGGCAAACCGTAACCAC CTGAAACTTCCAAACAACATGAACCAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGAGGATGCAACAAGTCTGATTACTGAGGGCTTT TTGCTAAATGCCTCCAATTACAAGCAGCTCACAAACGGCCACGGCTCTGCACACTGGATCGTCGGAAACTGGAGCGAGTGCTCCACCACA TGTGGCCTGGGGGCCTACTGGAGAAGGGTGGAGTGCAGCACCCAGATGGATTCTGACTGTGCGGCCATCCAGAGACCTGACCCTGCAAAA AGATGCCACCTCCGTCCCTGTGCTGGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAGAAACTGCAGTGGGGGCTTCAAGATACGCGAG ATTCAGTGCGTGGACAGCCGGGACCACCGGAACCTGAGGCCATTTCACTGCCAGTTCCTGGCCGGCATTCCTCCCCCATTGAGCATGAGC TGTAACCCGGAGCCCTGTGAGGCGTGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTCCTGTGGAGGTGGAGTTCAGGAGAGAGGAGTG TTCTGTCCAGGAGGCCTCTGTGATTGGACAAAAAGACCCACATCCACCATGTCTTGCAATGAGCACCTGTGCTGTCACTGGGCCACTGGG AACTGGGACCTGTGTTCCACTTCCTGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATGTGTGCCCTCAGAGGGCAATAAAACTGAAGAC CAAGACCAATGTCTATGTGATCACAAACCCAGACCTCCAGAATTCAAAAAATGCAACCAGCAGGCCTGCAAGAAAAGTGCCGATTTACTT TGCACTAAGGACAAACTGTCAGCCAGTTTCTGCCAGACACTGAAAGCCATGAAGAAATGTTCTGTGCCCACCGTGAGGGCTGAGTGCTGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SNX6_ENST00000362031_chr14_35099113_-_ADAMTS12_ENST00000504830_chr5_33751653_-_8070nt CTGGCCGCCGGCTCCCTCCGGCAGCAGGGAGATGCGCGCCTGCGCCGGCCCTCGCCTCGGAGCAGCCATGATGGAAGGCCTGGACGACGG CCCGGACTTCCTCTCAGAAGAGGACCGCGGAACTGGATTTTTCCAACTACCACATGGAGACTTTTTCATTGAACCCGTGAAGAAGCATCC ACTGGTTGAGGGAGGGTACCACCCGCACATCGTTTACAGGAGGCAGAAAGTTCCAGAAACCAAGGAGCCAACCTGTGGATTAAAGGACAG TGTTAACATCTCCCAGAAGCAAGAGCTATGGCGGGAGAAGTGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAG CAAGGAGAGATGGGTGGAGACACTGGTGGTGGCCGACACAAAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCAC CATCATGAACATGGTCACTGGGTTGTTCCATAACCCAAGCATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGA AGAAGAGCAAGGACTGAAAATAGTTCACCATGCAGAAAAGACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGA CCTCAATCCTGTTCATCACGACGTGGCTGTCCTTCTCACCAGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCT GTCTCACCTTTCAGGAATGTGTCAGCCTCACCGCAGTTGTAACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGA GCTAGGACACAGCTTCGGCATCCAGCATGATGGGAAAGAAAATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCT CCAGTACGATCCCACTCCGCTGACATGGTCCAAGTGCAGCGAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGA TGACATACCTAAAAAGAAAGGCTTGAAGTCCAAGGTCATTGCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGG ACCCAATGCTACCTTCTGCCAGGAAGTAGAAAACGTCTGCCAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGC TGCTGCAGATGGAACTCAATGTGGTGAGAAGAAGTGGTGTATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGG AGGCTGGGGCCGCTGGTCACCCTGGTCCCACTGTTCCAGGACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGA GCCAAAGTTTGGAGGGAAATATTGCACTGGAGAAAGAAAACGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATT TCGGCAGATGCAGTGCAGTGAATTTGACACTGTTCCCTACAAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGCACATCCTTG TGAGCTCTACTGCCGACCCATAGATGGCCAGTTTTCTGAGAAAATGCTGGATGCTGTCATTGATGGTACCCCTTGCTTTGAAGGCGGCAA CAGCAGAAATGTCTGTATTAATGGCATATGTAAGATGGTTGGCTGTGACTATGAGATCGATTCCAATGCCACCGAGGATCGCTGCGGTGT GTGCCTGGGAGATGGCTCTTCCTGCCAGACTGTGAGAAAGATGTTTAAGCAGAAGGAAGGATCTGGTTATGTTGACATTGGGCTCATTCC AAAAGGAGCAAGGGACATAAGAGTGATGGAAATTGAGGGAGCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCCTGAAAAATATTACCT GAATGGAGGGTTTATTATCCAGTGGAACGGGAACTATAAGCTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGGAGACCTGGAAAAGCT GATGGCCACAGGTCCCACCAATGAGTCTGTGTGGATCCAGCTTCTATTCCAGGTGACTAACCCTGGCATCAAGTATGAGTACACAATCCA GAAAGATGGCCTTGACAATGATGTTGAGCAGCAGATGTACTTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGTGACCTGCGGGACAGG TATCCGCCGCCAAACTGCCCATTGCATAAAGAAGGGCCGCGGGATGGTGAAAGCTACATTCTGTGACCCAGAAACACAGCCCAATGGGAG ACAGAAGAAGTGCCATGAAAAGGCTTGTCCACCCAGGTGGTGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATGCGGGCCCCACGGGGA GAAGAAGCGAACCGTGCTGTGCATCCAGACCATGGTCTCTGACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCACCTGCTGAAGCCCAA GACCCTCCTTTCCTGCAACAGAGACATCCTGTGCCCCTCGGACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGTTTCCTGTGGTGGTGG AGTGCGGATTCGCAGTGTCACATGTGCCAAGAACCATGATGAACCTTGCGATGTGACAAGGAAACCCAACAGCCGAGCTCTGTGTGGCCT CCAGCAATGCCCTTCTAGCCGGAGAGTTCTGAAACCAAACAAAGGCACTATTTCCAATGGAAAAAACCCACCAACACTAAAGCCCGTCCC TCCACCTACATCCAGGCCCAGAATGCTGACCACACCCACAGGGCCTGAGTCTATGAGCACAAGCACTCCAGCAATCAGCAGCCCTAGTCC TACCACAGCCTCCAAAGAAGGAGACCTGGGTGGGAAACAGTGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTCTCGCTATCTCATTTC CACTGGAAGCACTTCCCAGCCCATCCTCACTTCCCAATCCTTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAGTTCAGATACTGGTCC TACCTCGGAGGGAGGCCTTGTAGCTACAACAACAAGTGGTTCTGGCTTGTCATCTTCCCGCAACCCTATCACTTGGCCTGTGACTCCATT TTACAATACCTTGACCAAAGGTCCAGAAATGGAGATTCACAGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGACAAAGATGAAAGCAA TCCTGTAATATGGACCAAGATCAGAGTACCTGGAAATGACGCTCCAGTGGAAAGTACAGAAATGCCACTTGCACCTCCACTAACACCAGA TCTCAGCAGGGAGTCCTGGTGGCCACCCTTCAGCACAGTAATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTACTTCCGAAACTGGGAC ACCCAGAGTTGAGGGGATGGTTACTGAAAAGCCAGCCAACACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGAACCCTCAGGAAAGAC GGCAAACCGTAACCACCTGAAACTTCCAAACAACATGAACCAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGAGGATGCAACAAGTCT GATTACTGAGGGCTTTTTGCTAAATGCCTCCAATTACAAGCAGCTCACAAACGGCCACGGCTCTGCACACTGGATCGTCGGAAACTGGAG CGAGTGCTCCACCACATGTGGCCTGGGGGCCTACTGGAGAAGGGTGGAGTGCAGCACCCAGATGGATTCTGACTGTGCGGCCATCCAGAG ACCTGACCCTGCAAAAAGATGCCACCTCCGTCCCTGTGCTGGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAGAAACTGCAGTGGGGG CTTCAAGATACGCGAGATTCAGTGCGTGGACAGCCGGGACCACCGGAACCTGAGGCCATTTCACTGCCAGTTCCTGGCCGGCATTCCTCC CCCATTGAGCATGAGCTGTAACCCGGAGCCCTGTGAGGCGTGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTCCTGTGGAGGTGGAGT TCAGGAGAGAGGAGTGTTCTGTCCAGGAGGCCTCTGTGATTGGACAAAAAGACCCACATCCACCATGTCTTGCAATGAGCACCTGTGCTG TCACTGGGCCACTGGGAACTGGGACCTGTGTTCCACTTCCTGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATGTGTGCCCTCAGAGGG CAATAAAACTGAAGACCAAGACCAATGTCTATGTGATCACAAACCCAGACCTCCAGAATTCAAAAAATGCAACCAGCAGGCCTGCAAGAA AAGTGCCGATTTACTTTGCACTAAGGACAAACTGTCAGCCAGTTTCTGCCAGACACTGAAAGCCATGAAGAAATGTTCTGTGCCCACCGT GAGGGCTGAGTGCTGCTTCTCGTGTCCCCAGACACACATCACACACACCCAAAGGCAAAGAAGGCAACGGTTGCTCCAAAAGTCAAAAGA ACTCTAAGCCCAAAAGGAAGCCAGCTTCCACCAGACTGCAGCAGCCTGCTGACCATGACATGCTTTAGCCCTGGGAGCTGCTTCGTTGAG GTTTTGCTTCATATATTTCAGATTCAGCTTTGGGTCATGATGAAACAAAATCCATTGTGTTCCTCTAGCCACCGAATGTCCCTCACAGGA GGCCTAGGCTGCCGTACTTGCTGCTCCCTGATAGGAAGGTGAAATAGCTAGGAGAATCAGGCAGCACCTGGTATCGGCTCCTGGGAAAGG TGCCAGGTTAGACAGATTTGTGAAATACTGTATTTTTGTTCTCCCTTAAAGATAAAAACAAAGAGACCAGCTATTTCCCTGACTACCTCA AGAGTATCAGGCAACACTTACCCAGGGGACAAATAATCTTCTTAATTTATCTTGATGAATACCTTTCTTTTTTTTTTCTTGCCTCCCTGC CTGGGGCAGCTGCTATTTAAAATGTCACAGCGGAGCTTTAGGAACATTCCTTTAATTCATCCAGGCAGAGGACTGCTTTCTTCACCCCAT GTTCAACTAGGGCAGGAAGTGCTGGTTACATCCCTCAGTCTCTTCCTCCATCCCTGTAGGGCTCCATATCTGGGCTGCTTAGAGTCTCCT GCCAACCTTGGGACACTAGACTAAGAGGAAACAGGCATAAGAAACACAGCCTAAGGGGTTTAGGTCACTTACACAGAAAACACTTCTGGT TTGAAGAGCATTTCTATGAAAACTCGTAAAATGCAAATGAGCAGAAATCAATTTCTTAATATTACAGAAAAGGAACTGTGGGCCTTTATT CTTCCCACTTTCCTGGCAAATACACACTCCTTTGCAGAAGGGAAAATGTGTCTTCCTGGCTGACTTCCTCCCATCCTCCAGTCCCCACAG GAGGCCTGAGCTCAGGTCCCACCATCGTCTTGCTGCAGGGGCTGTATATGCAAAGACCACTATGACCAGCTCTAGGGCTGCCACCTGTCC TCACCTCTTCTCAGGTTGGAAAATGGAGGTTCCATATTAAAATATTTCAAAGAACCAGGTAAATTGTACTAAGTACAAGAACATAGTGCA AACTTCTAATCTAGAGAAAAAACATTTCTAAAAAGTAAGGTAAAGGGGATCTACTCCTCAGTGTACCCAATATGTAGTTAGTCTTAAAGA TCTTTTACTTTGGGGAGAACAGGTGAATCAGGGAGTCCAAAGAAACTGAAATGAAAGTTAGAATGCTTGTTCTGGATGTTCCTACCTCCC ACCAGAAGTCAAAGTAGGCTTGGTCTCAAATTCAGAGCAAATTTCTAGACAAAGTGATTTCTAAGGGAAGGTACTTACATGAACTGAACC CAGAGAAAGAGGGTAAGTGGGTGGGTGGAGGGGCATAAGCTTCAAATGAAAGAAGATATCAGAACCAATTCTTGACAGGGAGAAAGGCAA GGATGTGGCCTTCATGTGATGGGCAGCATATTTTCTGACTCATGCACAGATACACTTAATACTCCTCATGGAACACAATATCCCACGTCT CCCTTTACCTATCCGTTCAGCAGAATGGTGCTATTAAAAAAATGGTGCTAATATCTAGATGGTGGCAGAATTAATGTAAACATAGATAGG CATACAAATGGGTAAGTGTATGTGAAACTCTCCATATACATCTTCTGTTAAACATGTAACGGTGTTGCTGACCAATGCCAGTTTTATTGC TTGGGTACCTTGAATTTAAGATTTAATATTATGTGCTTTTTATTTTTTTCCAAGCCATTAACGTGTATTACTCTCATGAATTCCTGTGAA AAATAAAACAGTGGGATTGGGATGAAATTCAAGATAGACCAGAAACAGGAGGAAAGTACAAATGTTTACCTAAAGCCAGAGAATTTATTT CTAGATGATAATTACATTATTGTATTCTCTGCCTTTAAACATAAACATTGCTGGCCGATAGCAATCTCTGGTGAATAATGGTTTTCGAGG AGAGGAGACACTTAAATTGTTAGTGACATGAGTGGAGGAGAATCTGATATTTACTAATGAGGCAGTTTGCAAAGACTGTCCCTGAAGTGT AGTGTAGTCTTTCAGGGGGATTCATTTAGTAAGCTAGATTGATTTAACCTGGTACTGTACTAGCATAGGGTCAAATACGTGTCATCAGAG ACCTGGGTATGACCAGGCTTACAAAACTCAGGAACAAACTCAGATTCCTACTGACCTCAACCAACTAAACTAGGCCAAATTTCTCCGTGT ACAAAATGGACCACGTTATTTACAATCCACGTGGTGGAGAAGATGGTAGACATGTGGAGAGAGTTTGGCCAGGTGCTCCATTCTAGGTCT TTTTCCAGTTTCTCAAAGGCAGAACATTGGCTCCTAATTATTTGCCATGGATATTTGCTTCCTGTTCTGGAGCTATGTTGTAAGACAGCT GTGTGATGTCCATCATTCTTGACTCCAGAATGAAGACAGGGCTTGCTGTTTTCTGTCCTGTTGGTATCATCTGTTGCCTTGGCGATCACT CAGTGATGAGTCGTCAGTATTTTGACATGTCCCAGTGCTTGCTGTACAAGAGGGGACTCAGATCAACAGGAAGACTCTGAAGACAGGAAC CTGCATGGTATCTTACATCTTTGATACTTGGGTGCTGATATGAAGCAGAGTTGTTGATTTACTTTATCTAGGCCCTTCTTTCTTCTCACC TGGATCAAGCAACTGAGAAGTGTATCAGGAGACACTGGATACATATCTCTATGAAATAGAGAGGGCCATCGCAGGGCCTGGTACTTAACT ACATTAACGTTCTAAAACCCAGTTTGGTTTACGTTGTCTTTCACAGTAGTATATTTAGCTCTTCTCTGGAAAGTTGTGGGTTAATATAAT TCTTAAACATGAAAATGTAATTAAACACACCACGAGAGAACAATATTCCAGGAGACTTAATAGTGATTACTTTCTTCAATCAGGAAATCG TTTCAGTGCCTCCTTTGTAGGAATGCTTTGTTTTGTGATGGGTTTTCTTAAAGAAGAGCACACCTCCGTCCAATCTCCTGAGACAGCCAC GTCTCCGCTGACATCCCACTGTGATGCTTTCAGATAGTCAGTGAATGTTTCTGATAACCTTCATCCAGTATCTGAAACACAATGTGAGAG ATTATATTGTTTTAGATAATAACATCCCATTTAGTTGACTAAAATCTTCCAAACTCTGAAAGCTGCACACTGCTACTCCAGAGAGTGCAG GTCTTAGCTCTTCTCCTTTCTGACTTCAAGATGAATCTTTGGGACGATGTTTCTGGTGCTTGGTCCACAGTGATTCACTTTTGAAGGAGA GGCCACATGACATGAACTGCCTGGTGTTACAACCTAGCTAACATATTTGATGCTACTCCTGTTGTCTGTACTGCTTATTCAAGTAGTATT CTAAGTTATGTTACTAAAAAACATGGTGGGTAAAGCACAATCCTACCCATCATTGTCCTCCAAAATAATTGTATGACATACACGGCCCAG CCCATTGCCCTCCCTGCATCTCTGTGCTGCTTTGCCATTTCCCCTTCTACCCAGCCTCCTCAAGGGGTACCTTGGTGGATATTTCAGTAC >In-frame_SNX6_ENST00000362031_chr14_35099113_-_ADAMTS12_ENST00000352040_chr5_33751653_-_4169nt CTGGCCGCCGGCTCCCTCCGGCAGCAGGGAGATGCGCGCCTGCGCCGGCCCTCGCCTCGGAGCAGCCATGATGGAAGGCCTGGACGACGG CCCGGACTTCCTCTCAGAAGAGGACCGCGGAACTGGATTTTTCCAACTACCACATGGAGACTTTTTCATTGAACCCGTGAAGAAGCATCC ACTGGTTGAGGGAGGGTACCACCCGCACATCGTTTACAGGAGGCAGAAAGTTCCAGAAACCAAGGAGCCAACCTGTGGATTAAAGGACAG TGTTAACATCTCCCAGAAGCAAGAGCTATGGCGGGAGAAGTGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAG CAAGGAGAGATGGGTGGAGACACTGGTGGTGGCCGACACAAAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCAC CATCATGAACATGGTCACTGGGTTGTTCCATAACCCAAGCATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGA AGAAGAGCAAGGACTGAAAATAGTTCACCATGCAGAAAAGACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGA CCTCAATCCTGTTCATCACGACGTGGCTGTCCTTCTCACCAGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCT GTCTCACCTTTCAGGAATGTGTCAGCCTCACCGCAGTTGTAACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGA GCTAGGACACAGCTTCGGCATCCAGCATGATGGGAAAGAAAATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCT CCAGTACGATCCCACTCCGCTGACATGGTCCAAGTGCAGCGAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGA TGACATACCTAAAAAGAAAGGCTTGAAGTCCAAGGTCATTGCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGG ACCCAATGCTACCTTCTGCCAGGAAGTAGAAAACGTCTGCCAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGC TGCTGCAGATGGAACTCAATGTGGTGAGAAGAAGTGGTGTATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGG AGGCTGGGGCCGCTGGTCACCCTGGTCCCACTGTTCCAGGACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGA GCCAAAGTTTGGAGGGAAATATTGCACTGGAGAAAGAAAACGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATT TCGGCAGATGCAGTGCAGTGAATTTGACACTGTTCCCTACAAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGGTTATGTTGA CATTGGGCTCATTCCAAAAGGAGCAAGGGACATAAGAGTGATGGAAATTGAGGGAGCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCC TGAAAAATATTACCTGAATGGAGGGTTTATTATCCAGTGGAACGGGAACTATAAGCTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGG AGACCTGGAAAAGCTGATGGCCACAGGTCCCACCAATGAGTCTGTGTGGATCCAGCTTCTATTCCAGGTGACTAACCCTGGCATCAAGTA TGAGTACACAATCCAGAAAGATGGCCTTGACAATGATGTTGAGCAGCAGATGTACTTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGT GACCTGCGGGACAGGTATCCGCCGCCAAACTGCCCATTGCATAAAGAAGGGCCGCGGGATGGTGAAAGCTACATTCTGTGACCCAGAAAC ACAGCCCAATGGGAGACAGAAGAAGTGCCATGAAAAGGCTTGTCCACCCAGGTGGTGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATG CGGGCCCCACGGGGAGAAGAAGCGAACCGTGCTGTGCATCCAGACCATGGTCTCTGACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCA CCTGCTGAAGCCCAAGACCCTCCTTTCCTGCAACAGAGACATCCTGTGCCCCTCGGACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGT TTCCTGTGGTGGTGGAGTGCGGATTCGCAGTGTCACATGTGCCAAGAACCATGATGAACCTTGCGATGTGACAAGGAAACCCAACAGCCG AGCTCTGTGTGGCCTCCAGCAATGCCCTTCTAGCCGGAGAGTTCTGAAACCAAACAAAGGCACTATTTCCAATGGAAAAAACCCACCAAC ACTAAAGCCCGTCCCTCCACCTACATCCAGGCCCAGAATGCTGACCACACCCACAGGGCCTGAGTCTATGAGCACAAGCACTCCAGCAAT CAGCAGCCCTAGTCCTACCACAGCCTCCAAAGAAGGAGACCTGGGTGGGAAACAGTGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTC TCGCTATCTCATTTCCACTGGAAGCACTTCCCAGCCCATCCTCACTTCCCAATCCTTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAG TTCAGATACTGGTCCTACCTCGGAGGGAGGCCTTGTAGCTACAACAACAAGTGGTTCTGGCTTGTCATCTTCCCGCAACCCTATCACTTG GCCTGTGACTCCATTTTACAATACCTTGACCAAAGGTCCAGAAATGGAGATTCACAGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGA CAAAGATGAAAGCAATCCTGTAATATGGACCAAGATCAGAGTACCTGGAAATGACGCTCCAGTGGAAAGTACAGAAATGCCACTTGCACC TCCACTAACACCAGATCTCAGCAGGGAGTCCTGGTGGCCACCCTTCAGCACAGTAATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTAC TTCCGAAACTGGGACACCCAGAGTTGAGGGGATGGTTACTGAAAAGCCAGCCAACACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGA ACCCTCAGGAAAGACGGCAAACCGTAACCACCTGAAACTTCCAAACAACATGAACCAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGA GGATGCAACAAGTCTGATTACTGAGGGCTTTTTGCTAAATGCCTCCAATTACAAGCAGCTCACAAACGGCCACGGCTCTGCACACTGGAT CGTCGGAAACTGGAGCGAGTGCTCCACCACATGTGGCCTGGGGGCCTACTGGAGAAGGGTGGAGTGCAGCACCCAGATGGATTCTGACTG TGCGGCCATCCAGAGACCTGACCCTGCAAAAAGATGCCACCTCCGTCCCTGTGCTGGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAG AAACTGCAGTGGGGGCTTCAAGATACGCGAGATTCAGTGCGTGGACAGCCGGGACCACCGGAACCTGAGGCCATTTCACTGCCAGTTCCT GGCCGGCATTCCTCCCCCATTGAGCATGAGCTGTAACCCGGAGCCCTGTGAGGCGTGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTC CTGTGGAGGTGGAGTTCAGGAGAGAGGAGTGTTCTGTCCAGGAGGCCTCTGTGATTGGACAAAAAGACCCACATCCACCATGTCTTGCAA TGAGCACCTGTGCTGTCACTGGGCCACTGGGAACTGGGACCTGTGTTCCACTTCCTGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATG TGTGCCCTCAGAGGGCAATAAAACTGAAGACCAAGACCAATGTCTATGTGATCACAAACCCAGACCTCCAGAATTCAAAAAATGCAACCA GCAGGCCTGCAAGAAAAGTGCCGATTTACTTTGCACTAAGGACAAACTGTCAGCCAGTTTCTGCCAGACACTGAAAGCCATGAAGAAATG TTCTGTGCCCACCGTGAGGGCTGAGTGCTGCTTCTCGTGTCCCCAGACACACATCACACACACCCAAAGGCAAAGAAGGCAACGGTTGCT |
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FusionGenePPI for SNX6_ADAMTS12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SNX6 | PIM1, SNX4, SNX2, BMPR1B, ACVR2B, ACVRL1, SNX1, TGFBR2, TGFBR1, PDGFRA, INSR, EGFR, LEPR, CALM1, DISC1, NDEL1, TNIK, ELAVL1, GIT1, COIL, PHLPP1, BRCA1, CSNK2A2, GTF2A1, H3F3A, RTF1, ANP32E, APEH, ATG7, ATP6V1C1, FAM129B, PAWR, SHMT1, SHMT2, STAT1, TSNAX, VPS29, VPS35, TSN, BRMS1, ESR1, USP46, FAM221A, DNM3, TEAD4, TREML2, FAM43A, CAMKMT, CCNL2, GATS, VAPB, IMPDH2, PCID2, IFI16, HERC2, PTPRR, MTM1, SNX32, POTEB3, TSPYL1, HENMT1, TCTEX1D2, SNRNP27, CCDC102B, USP47, FGB, EPB42 | ADAMTS12 | CALM2, MEOX2, MYL6, UBR1, FKBP9, SP3, PPM1A, SNRK, USF2, USF1, RUFY3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SNX6_ADAMTS12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SNX6_ADAMTS12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ADAMTS12 | C0036341 | Schizophrenia | 1 | PSYGENET |
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