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Fusion gene ID: 35086 |
FusionGeneSummary for SND1_IMMP2L |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SND1_IMMP2L | Fusion gene ID: 35086 | Hgene | Tgene | Gene symbol | SND1 | IMMP2L | Gene ID | 27044 | 83943 |
| Gene name | staphylococcal nuclease and tudor domain containing 1 | inner mitochondrial membrane peptidase subunit 2 | |
| Synonyms | TDRD11|Tudor-SN|p100 | IMMP2L-IT1|IMP2|IMP2-LIKE | |
| Cytomap | 7q32.1 | 7q31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | staphylococcal nuclease domain-containing protein 1EBNA2 coactivator p100testis tissue sperm-binding protein Li 82Ptudor domain-containing protein 11 | mitochondrial inner membrane protease subunit 2IMP2 inner mitochondrial membrane peptidase-likeIMP2 inner mitochondrial membrane protease-likeinner mitochondrial membrane peptidase 2 like | |
| Modification date | 20180523 | 20180526 | |
| UniProtAcc | Q7KZF4 | Q96T52 | |
| Ensembl transtripts involved in fusion gene | ENST00000354725, ENST00000467238, | ENST00000405709, ENST00000331762, ENST00000452895, ENST00000415362, ENST00000447215, ENST00000437687, ENST00000489381, ENST00000450877, | |
| Fusion gene scores | * DoF score | 13 X 14 X 7=1274 | 15 X 7 X 10=1050 |
| # samples | 20 | 15 | |
| ** MAII score | log2(20/1274*10)=-2.67129337248158 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/1050*10)=-2.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SND1 [Title/Abstract] AND IMMP2L [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-FX-A3RE-01A | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| TCGA | LD | SARC | TCGA-FX-A3TO-01A | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000354725 | ENST00000405709 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000354725 | ENST00000331762 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000354725 | ENST00000452895 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| In-frame | ENST00000354725 | ENST00000415362 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-intron | ENST00000354725 | ENST00000447215 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-intron | ENST00000354725 | ENST00000437687 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-5UTR | ENST00000354725 | ENST00000489381 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| 5CDS-5UTR | ENST00000354725 | ENST00000450877 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000467238 | ENST00000405709 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000467238 | ENST00000331762 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000467238 | ENST00000452895 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-3CDS | ENST00000467238 | ENST00000415362 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-intron | ENST00000467238 | ENST00000447215 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-intron | ENST00000467238 | ENST00000437687 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-5UTR | ENST00000467238 | ENST00000489381 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
| intron-5UTR | ENST00000467238 | ENST00000450877 | SND1 | chr7 | 127569382 | + | IMMP2L | chr7 | 110303777 | - |
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FusionProtFeatures for SND1_IMMP2L |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SND1 | IMMP2L |
| Functions as a bridging factor between STAT6 and thebasal transcription factor. Plays a role in PIM1 regulation of MYBactivity. Functions as a transcriptional coactivator for theEpstein-Barr virus nuclear antigen 2 (EBNA2).{ECO:0000269|PubMed:7651391}. | Catalyzes the removal of transit peptides required forthe targeting of proteins from the mitochondrial matrix, acrossthe inner membrane, into the inter-membrane space. Known toprocess the nuclear encoded protein DIABLO.{ECO:0000269|PubMed:15814844}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for SND1_IMMP2L |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000331762_chr7_110303777_-_596aa MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKL IGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCHN QNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCATVTIGGINI AEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000452895_chr7_110303777_-_596aa MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKL IGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCHN QNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCATVTIGGINI AEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000415362_chr7_110303777_-_596aa MASSAQSGGSSGGPAVPTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKL IGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTI ENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCHN QNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKL NSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCATVTIGGINI AEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000331762_chr7_110303777_-_1789nt ATGGCGTCCTCCGCGCAGAGCGGCGGCTCCTCCGGGGGACCCGCGGTCCCCACCGTGCAGCGGGGCATCATCAAGATGGTCCTCTCAGGG TGCGCCATCATTGTCCGAGGTCAGCCTCGTGGTGGGCCTCCTCCTGAGCGGCAGATCAACCTCAGCAACATTCGTGCTGGAAATCTTGCT CGCCGGGCAGCCGCCACACAACCTGATGCAAAGGATACCCCTGATGAGCCCTGGGCATTTCCAGCTCGAGAGTTCCTTCGAAAGAAGCTG ATTGGGAAGGAAGTCTGTTTCACGATAGAAAACAAGACTCCCCAGGGGCGAGAGTATGGCATGATCTACCTTGGAAAAGATACCAATGGG GAAAACATTGCAGAATCACTGGTTGCAGAGGGCTTAGCCACCCGGAGAGAAGGCATGAGAGCTAATAATCCTGAGCAGAACCGGCTTTCA GAATGTGAAGAACAAGCAAAGGCAGCCAAGAAAGGGATGTGGAGTGAGGGGAACGGTTCACATACTATCCGGGATCTCAAGTATACCATT GAAAACCCAAGGCACTTTGTGGACTCACACCACCAGAAGCCTGTTAATGCTATCATCGAGCATGTGCGGGACGGCAGTGTGGTCAGGGCC CTGCTCCTCCCAGATTACTACCTGGTTACAGTCATGCTGTCAGGCATCAAGTGCCCAACTTTTCGACGGGAAGCAGATGGCAGTGAAACT CCAGAGCCTTTTGCTGCAGAAGCCAAATTTTTCACTGAGTCGCGACTGCTTCAGAGAGATGTTCAGATCATTCTGGAGAGCTGCCACAAC CAGAACATTCTGGGTACCATCCTTCATCCAAATGGCAACATCACAGAGCTCCTCCTGAAGGAAGGTTTCGCACGCTGTGTGGACTGGTCG ATTGCAGTTTACACCCGGGGCGCAGAAAAGCTGAGGGCGGCAGAGAGGTTTGCCAAAGAGCGCAGGCTGAGAATATGGAGAGACTATGTG GCTCCCACAGCTAATTTGGACCAAAAGGACAAGCAGTTTGTTGCCAAGGTGATGCAGGTTCTGAATGCTGATGCCATTGTTGTGAAGCTG AACTCAGGCGATTACAAGACGATTCACCTGTCCAGCATCCGACCACCGAGGCTGGAGGGGGAGAACACCCAGGATAAGAACAAGAAACTG CGTCCCCTGTATGACATTCCTTACATGTTTGAGGCCCGGGAATTTCTTCGAAAAAAGCTTATTGGGAAGAAGGTCAATGTGACGGTGGAC TACATTAGACCAGCCAGCCCAGCCACAGAGACAGTGCCTGCCTTTTCAGAGCGTACCTGTGCCACTGTCACCATTGGAGGAATAAACATT GCTGAGGCTCTTGTCAGCAAAGGTCTAGCCACAGTGATCAGATACCGGCAGGATGATGACCAGAGATCATCACACTACGATGAACTGCTT GCTGCAGAGGCCAGAGCTATTAAGAATGGCAAAGGATTGCATAGCAAGAAGGAAGTGCCTATCCACCGTGTTGCAGATATATCTGGGGAT ACCCAAAAAGCAAAGCAGTTCCTGCCTTTTCTTCAGCGGGCAGGTCGTTCTGAAGCTGTGGTGGAATACGTCTTCAGTGGTTCTCGTCTC AAACTCTATTTGCCAAAGGAAACTTGCCTTATCACCTTCTTGCTTGCAGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCT >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000452895_chr7_110303777_-_1789nt ATGGCGTCCTCCGCGCAGAGCGGCGGCTCCTCCGGGGGACCCGCGGTCCCCACCGTGCAGCGGGGCATCATCAAGATGGTCCTCTCAGGG TGCGCCATCATTGTCCGAGGTCAGCCTCGTGGTGGGCCTCCTCCTGAGCGGCAGATCAACCTCAGCAACATTCGTGCTGGAAATCTTGCT CGCCGGGCAGCCGCCACACAACCTGATGCAAAGGATACCCCTGATGAGCCCTGGGCATTTCCAGCTCGAGAGTTCCTTCGAAAGAAGCTG ATTGGGAAGGAAGTCTGTTTCACGATAGAAAACAAGACTCCCCAGGGGCGAGAGTATGGCATGATCTACCTTGGAAAAGATACCAATGGG GAAAACATTGCAGAATCACTGGTTGCAGAGGGCTTAGCCACCCGGAGAGAAGGCATGAGAGCTAATAATCCTGAGCAGAACCGGCTTTCA GAATGTGAAGAACAAGCAAAGGCAGCCAAGAAAGGGATGTGGAGTGAGGGGAACGGTTCACATACTATCCGGGATCTCAAGTATACCATT GAAAACCCAAGGCACTTTGTGGACTCACACCACCAGAAGCCTGTTAATGCTATCATCGAGCATGTGCGGGACGGCAGTGTGGTCAGGGCC CTGCTCCTCCCAGATTACTACCTGGTTACAGTCATGCTGTCAGGCATCAAGTGCCCAACTTTTCGACGGGAAGCAGATGGCAGTGAAACT CCAGAGCCTTTTGCTGCAGAAGCCAAATTTTTCACTGAGTCGCGACTGCTTCAGAGAGATGTTCAGATCATTCTGGAGAGCTGCCACAAC CAGAACATTCTGGGTACCATCCTTCATCCAAATGGCAACATCACAGAGCTCCTCCTGAAGGAAGGTTTCGCACGCTGTGTGGACTGGTCG ATTGCAGTTTACACCCGGGGCGCAGAAAAGCTGAGGGCGGCAGAGAGGTTTGCCAAAGAGCGCAGGCTGAGAATATGGAGAGACTATGTG GCTCCCACAGCTAATTTGGACCAAAAGGACAAGCAGTTTGTTGCCAAGGTGATGCAGGTTCTGAATGCTGATGCCATTGTTGTGAAGCTG AACTCAGGCGATTACAAGACGATTCACCTGTCCAGCATCCGACCACCGAGGCTGGAGGGGGAGAACACCCAGGATAAGAACAAGAAACTG CGTCCCCTGTATGACATTCCTTACATGTTTGAGGCCCGGGAATTTCTTCGAAAAAAGCTTATTGGGAAGAAGGTCAATGTGACGGTGGAC TACATTAGACCAGCCAGCCCAGCCACAGAGACAGTGCCTGCCTTTTCAGAGCGTACCTGTGCCACTGTCACCATTGGAGGAATAAACATT GCTGAGGCTCTTGTCAGCAAAGGTCTAGCCACAGTGATCAGATACCGGCAGGATGATGACCAGAGATCATCACACTACGATGAACTGCTT GCTGCAGAGGCCAGAGCTATTAAGAATGGCAAAGGATTGCATAGCAAGAAGGAAGTGCCTATCCACCGTGTTGCAGATATATCTGGGGAT ACCCAAAAAGCAAAGCAGTTCCTGCCTTTTCTTCAGCGGGCAGGTCGTTCTGAAGCTGTGGTGGAATACGTCTTCAGTGGTTCTCGTCTC AAACTCTATTTGCCAAAGGAAACTTGCCTTATCACCTTCTTGCTTGCAGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCT >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000415362_chr7_110303777_-_1789nt ATGGCGTCCTCCGCGCAGAGCGGCGGCTCCTCCGGGGGACCCGCGGTCCCCACCGTGCAGCGGGGCATCATCAAGATGGTCCTCTCAGGG TGCGCCATCATTGTCCGAGGTCAGCCTCGTGGTGGGCCTCCTCCTGAGCGGCAGATCAACCTCAGCAACATTCGTGCTGGAAATCTTGCT CGCCGGGCAGCCGCCACACAACCTGATGCAAAGGATACCCCTGATGAGCCCTGGGCATTTCCAGCTCGAGAGTTCCTTCGAAAGAAGCTG ATTGGGAAGGAAGTCTGTTTCACGATAGAAAACAAGACTCCCCAGGGGCGAGAGTATGGCATGATCTACCTTGGAAAAGATACCAATGGG GAAAACATTGCAGAATCACTGGTTGCAGAGGGCTTAGCCACCCGGAGAGAAGGCATGAGAGCTAATAATCCTGAGCAGAACCGGCTTTCA GAATGTGAAGAACAAGCAAAGGCAGCCAAGAAAGGGATGTGGAGTGAGGGGAACGGTTCACATACTATCCGGGATCTCAAGTATACCATT GAAAACCCAAGGCACTTTGTGGACTCACACCACCAGAAGCCTGTTAATGCTATCATCGAGCATGTGCGGGACGGCAGTGTGGTCAGGGCC CTGCTCCTCCCAGATTACTACCTGGTTACAGTCATGCTGTCAGGCATCAAGTGCCCAACTTTTCGACGGGAAGCAGATGGCAGTGAAACT CCAGAGCCTTTTGCTGCAGAAGCCAAATTTTTCACTGAGTCGCGACTGCTTCAGAGAGATGTTCAGATCATTCTGGAGAGCTGCCACAAC CAGAACATTCTGGGTACCATCCTTCATCCAAATGGCAACATCACAGAGCTCCTCCTGAAGGAAGGTTTCGCACGCTGTGTGGACTGGTCG ATTGCAGTTTACACCCGGGGCGCAGAAAAGCTGAGGGCGGCAGAGAGGTTTGCCAAAGAGCGCAGGCTGAGAATATGGAGAGACTATGTG GCTCCCACAGCTAATTTGGACCAAAAGGACAAGCAGTTTGTTGCCAAGGTGATGCAGGTTCTGAATGCTGATGCCATTGTTGTGAAGCTG AACTCAGGCGATTACAAGACGATTCACCTGTCCAGCATCCGACCACCGAGGCTGGAGGGGGAGAACACCCAGGATAAGAACAAGAAACTG CGTCCCCTGTATGACATTCCTTACATGTTTGAGGCCCGGGAATTTCTTCGAAAAAAGCTTATTGGGAAGAAGGTCAATGTGACGGTGGAC TACATTAGACCAGCCAGCCCAGCCACAGAGACAGTGCCTGCCTTTTCAGAGCGTACCTGTGCCACTGTCACCATTGGAGGAATAAACATT GCTGAGGCTCTTGTCAGCAAAGGTCTAGCCACAGTGATCAGATACCGGCAGGATGATGACCAGAGATCATCACACTACGATGAACTGCTT GCTGCAGAGGCCAGAGCTATTAAGAATGGCAAAGGATTGCATAGCAAGAAGGAAGTGCCTATCCACCGTGTTGCAGATATATCTGGGGAT ACCCAAAAAGCAAAGCAGTTCCTGCCTTTTCTTCAGCGGGCAGGTCGTTCTGAAGCTGTGGTGGAATACGTCTTCAGTGGTTCTCGTCTC AAACTCTATTTGCCAAAGGAAACTTGCCTTATCACCTTCTTGCTTGCAGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000331762_chr7_110303777_-_2531nt GGCGGAGATCGCGTCTCTTTCGCTCCGTGTCCCGCTGCTGCTCCTGTGAGCGCCCGGCGAGTCCGTCCCGTCCACCGTCCGCAGCTGGTA GCCAGCCTGCCCCTCGCCTCGACTCCCTTTCACCAACACCGACACCCACATTGACACCTCCAGTCCGGCCAGCCGCTCCACTCGTTGCCT TTGCATCTCCACACATGGCGTCCTCCGCGCAGAGCGGCGGCTCCTCCGGGGGACCCGCGGTCCCCACCGTGCAGCGGGGCATCATCAAGA TGGTCCTCTCAGGGTGCGCCATCATTGTCCGAGGTCAGCCTCGTGGTGGGCCTCCTCCTGAGCGGCAGATCAACCTCAGCAACATTCGTG CTGGAAATCTTGCTCGCCGGGCAGCCGCCACACAACCTGATGCAAAGGATACCCCTGATGAGCCCTGGGCATTTCCAGCTCGAGAGTTCC TTCGAAAGAAGCTGATTGGGAAGGAAGTCTGTTTCACGATAGAAAACAAGACTCCCCAGGGGCGAGAGTATGGCATGATCTACCTTGGAA AAGATACCAATGGGGAAAACATTGCAGAATCACTGGTTGCAGAGGGCTTAGCCACCCGGAGAGAAGGCATGAGAGCTAATAATCCTGAGC AGAACCGGCTTTCAGAATGTGAAGAACAAGCAAAGGCAGCCAAGAAAGGGATGTGGAGTGAGGGGAACGGTTCACATACTATCCGGGATC TCAAGTATACCATTGAAAACCCAAGGCACTTTGTGGACTCACACCACCAGAAGCCTGTTAATGCTATCATCGAGCATGTGCGGGACGGCA GTGTGGTCAGGGCCCTGCTCCTCCCAGATTACTACCTGGTTACAGTCATGCTGTCAGGCATCAAGTGCCCAACTTTTCGACGGGAAGCAG ATGGCAGTGAAACTCCAGAGCCTTTTGCTGCAGAAGCCAAATTTTTCACTGAGTCGCGACTGCTTCAGAGAGATGTTCAGATCATTCTGG AGAGCTGCCACAACCAGAACATTCTGGGTACCATCCTTCATCCAAATGGCAACATCACAGAGCTCCTCCTGAAGGAAGGTTTCGCACGCT GTGTGGACTGGTCGATTGCAGTTTACACCCGGGGCGCAGAAAAGCTGAGGGCGGCAGAGAGGTTTGCCAAAGAGCGCAGGCTGAGAATAT GGAGAGACTATGTGGCTCCCACAGCTAATTTGGACCAAAAGGACAAGCAGTTTGTTGCCAAGGTGATGCAGGTTCTGAATGCTGATGCCA TTGTTGTGAAGCTGAACTCAGGCGATTACAAGACGATTCACCTGTCCAGCATCCGACCACCGAGGCTGGAGGGGGAGAACACCCAGGATA AGAACAAGAAACTGCGTCCCCTGTATGACATTCCTTACATGTTTGAGGCCCGGGAATTTCTTCGAAAAAAGCTTATTGGGAAGAAGGTCA ATGTGACGGTGGACTACATTAGACCAGCCAGCCCAGCCACAGAGACAGTGCCTGCCTTTTCAGAGCGTACCTGTGCCACTGTCACCATTG GAGGAATAAACATTGCTGAGGCTCTTGTCAGCAAAGGTCTAGCCACAGTGATCAGATACCGGCAGGATGATGACCAGAGATCATCACACT ACGATGAACTGCTTGCTGCAGAGGCCAGAGCTATTAAGAATGGCAAAGGATTGCATAGCAAGAAGGAAGTGCCTATCCACCGTGTTGCAG ATATATCTGGGGATACCCAAAAAGCAAAGCAGTTCCTGCCTTTTCTTCAGCGGGCAGGTCGTTCTGAAGCTGTGGTGGAATACGTCTTCA GTGGTTCTCGTCTCAAACTCTATTTGCCAAAGGAAACTTGCCTTATCACCTTCTTGCTTGCAGGTTTCCCTAGGACTTCTGCATGCCCAT GCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAA TGACTGCATGAATCTACCTGAGTTGCTGGCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTT CTGACAATATGATGCTGTGCGAGAAATATTTACAGCACATTAAAACGATCTGTATTATTAAATAAATAATTTTCAAATGTTAAACAGTAT TAAATGGCACCTGATTTTGTGTTAAATTTTAGTTCCCTGTTGTTTAATGCCCCCAAAATATGCAGACCTTTGGGAATATAAAAATATTGC ACCCACATGTCTTAATGGGGCTGAATTTCAGATTATTTGTTACATATACTTATTATATTGATTGTTGGGTTTTGATTTTGGTGCTTGCTG CTGAAATAAATTGAAAATTAATATTCAATAAAAATGATGTATTTGTCACTTGCTGTTAAGGTAGAACAAGAAGGAACACATATTATACAC ATAATGATGGGAATTACATTGTGATTTGTACTATCTACAAAGGAGTAACTGCCAGTTAGGAAGAACAGTAAACAGTGATGTTAAAATAAA >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000452895_chr7_110303777_-_2169nt GGCGGAGATCGCGTCTCTTTCGCTCCGTGTCCCGCTGCTGCTCCTGTGAGCGCCCGGCGAGTCCGTCCCGTCCACCGTCCGCAGCTGGTA GCCAGCCTGCCCCTCGCCTCGACTCCCTTTCACCAACACCGACACCCACATTGACACCTCCAGTCCGGCCAGCCGCTCCACTCGTTGCCT TTGCATCTCCACACATGGCGTCCTCCGCGCAGAGCGGCGGCTCCTCCGGGGGACCCGCGGTCCCCACCGTGCAGCGGGGCATCATCAAGA TGGTCCTCTCAGGGTGCGCCATCATTGTCCGAGGTCAGCCTCGTGGTGGGCCTCCTCCTGAGCGGCAGATCAACCTCAGCAACATTCGTG CTGGAAATCTTGCTCGCCGGGCAGCCGCCACACAACCTGATGCAAAGGATACCCCTGATGAGCCCTGGGCATTTCCAGCTCGAGAGTTCC TTCGAAAGAAGCTGATTGGGAAGGAAGTCTGTTTCACGATAGAAAACAAGACTCCCCAGGGGCGAGAGTATGGCATGATCTACCTTGGAA AAGATACCAATGGGGAAAACATTGCAGAATCACTGGTTGCAGAGGGCTTAGCCACCCGGAGAGAAGGCATGAGAGCTAATAATCCTGAGC AGAACCGGCTTTCAGAATGTGAAGAACAAGCAAAGGCAGCCAAGAAAGGGATGTGGAGTGAGGGGAACGGTTCACATACTATCCGGGATC TCAAGTATACCATTGAAAACCCAAGGCACTTTGTGGACTCACACCACCAGAAGCCTGTTAATGCTATCATCGAGCATGTGCGGGACGGCA GTGTGGTCAGGGCCCTGCTCCTCCCAGATTACTACCTGGTTACAGTCATGCTGTCAGGCATCAAGTGCCCAACTTTTCGACGGGAAGCAG ATGGCAGTGAAACTCCAGAGCCTTTTGCTGCAGAAGCCAAATTTTTCACTGAGTCGCGACTGCTTCAGAGAGATGTTCAGATCATTCTGG AGAGCTGCCACAACCAGAACATTCTGGGTACCATCCTTCATCCAAATGGCAACATCACAGAGCTCCTCCTGAAGGAAGGTTTCGCACGCT GTGTGGACTGGTCGATTGCAGTTTACACCCGGGGCGCAGAAAAGCTGAGGGCGGCAGAGAGGTTTGCCAAAGAGCGCAGGCTGAGAATAT GGAGAGACTATGTGGCTCCCACAGCTAATTTGGACCAAAAGGACAAGCAGTTTGTTGCCAAGGTGATGCAGGTTCTGAATGCTGATGCCA TTGTTGTGAAGCTGAACTCAGGCGATTACAAGACGATTCACCTGTCCAGCATCCGACCACCGAGGCTGGAGGGGGAGAACACCCAGGATA AGAACAAGAAACTGCGTCCCCTGTATGACATTCCTTACATGTTTGAGGCCCGGGAATTTCTTCGAAAAAAGCTTATTGGGAAGAAGGTCA ATGTGACGGTGGACTACATTAGACCAGCCAGCCCAGCCACAGAGACAGTGCCTGCCTTTTCAGAGCGTACCTGTGCCACTGTCACCATTG GAGGAATAAACATTGCTGAGGCTCTTGTCAGCAAAGGTCTAGCCACAGTGATCAGATACCGGCAGGATGATGACCAGAGATCATCACACT ACGATGAACTGCTTGCTGCAGAGGCCAGAGCTATTAAGAATGGCAAAGGATTGCATAGCAAGAAGGAAGTGCCTATCCACCGTGTTGCAG ATATATCTGGGGATACCCAAAAAGCAAAGCAGTTCCTGCCTTTTCTTCAGCGGGCAGGTCGTTCTGAAGCTGTGGTGGAATACGTCTTCA GTGGTTCTCGTCTCAAACTCTATTTGCCAAAGGAAACTTGCCTTATCACCTTCTTGCTTGCAGGTTTCCCTAGGACTTCTGCATGCCCAT GCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAA TGACTGCATGAATCTACCTGAGTTGCTGGCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTT CTGACAATATGATGCTGTGCGAGAAATATTTACAGCACATTAAAACGATCTGTATTATTAAATAAATAATTTTCAAATGTTAAACAGTAT >In-frame_SND1_ENST00000354725_chr7_127569382_+_IMMP2L_ENST00000415362_chr7_110303777_-_1983nt GGCGGAGATCGCGTCTCTTTCGCTCCGTGTCCCGCTGCTGCTCCTGTGAGCGCCCGGCGAGTCCGTCCCGTCCACCGTCCGCAGCTGGTA GCCAGCCTGCCCCTCGCCTCGACTCCCTTTCACCAACACCGACACCCACATTGACACCTCCAGTCCGGCCAGCCGCTCCACTCGTTGCCT TTGCATCTCCACACATGGCGTCCTCCGCGCAGAGCGGCGGCTCCTCCGGGGGACCCGCGGTCCCCACCGTGCAGCGGGGCATCATCAAGA TGGTCCTCTCAGGGTGCGCCATCATTGTCCGAGGTCAGCCTCGTGGTGGGCCTCCTCCTGAGCGGCAGATCAACCTCAGCAACATTCGTG CTGGAAATCTTGCTCGCCGGGCAGCCGCCACACAACCTGATGCAAAGGATACCCCTGATGAGCCCTGGGCATTTCCAGCTCGAGAGTTCC TTCGAAAGAAGCTGATTGGGAAGGAAGTCTGTTTCACGATAGAAAACAAGACTCCCCAGGGGCGAGAGTATGGCATGATCTACCTTGGAA AAGATACCAATGGGGAAAACATTGCAGAATCACTGGTTGCAGAGGGCTTAGCCACCCGGAGAGAAGGCATGAGAGCTAATAATCCTGAGC AGAACCGGCTTTCAGAATGTGAAGAACAAGCAAAGGCAGCCAAGAAAGGGATGTGGAGTGAGGGGAACGGTTCACATACTATCCGGGATC TCAAGTATACCATTGAAAACCCAAGGCACTTTGTGGACTCACACCACCAGAAGCCTGTTAATGCTATCATCGAGCATGTGCGGGACGGCA GTGTGGTCAGGGCCCTGCTCCTCCCAGATTACTACCTGGTTACAGTCATGCTGTCAGGCATCAAGTGCCCAACTTTTCGACGGGAAGCAG ATGGCAGTGAAACTCCAGAGCCTTTTGCTGCAGAAGCCAAATTTTTCACTGAGTCGCGACTGCTTCAGAGAGATGTTCAGATCATTCTGG AGAGCTGCCACAACCAGAACATTCTGGGTACCATCCTTCATCCAAATGGCAACATCACAGAGCTCCTCCTGAAGGAAGGTTTCGCACGCT GTGTGGACTGGTCGATTGCAGTTTACACCCGGGGCGCAGAAAAGCTGAGGGCGGCAGAGAGGTTTGCCAAAGAGCGCAGGCTGAGAATAT GGAGAGACTATGTGGCTCCCACAGCTAATTTGGACCAAAAGGACAAGCAGTTTGTTGCCAAGGTGATGCAGGTTCTGAATGCTGATGCCA TTGTTGTGAAGCTGAACTCAGGCGATTACAAGACGATTCACCTGTCCAGCATCCGACCACCGAGGCTGGAGGGGGAGAACACCCAGGATA AGAACAAGAAACTGCGTCCCCTGTATGACATTCCTTACATGTTTGAGGCCCGGGAATTTCTTCGAAAAAAGCTTATTGGGAAGAAGGTCA ATGTGACGGTGGACTACATTAGACCAGCCAGCCCAGCCACAGAGACAGTGCCTGCCTTTTCAGAGCGTACCTGTGCCACTGTCACCATTG GAGGAATAAACATTGCTGAGGCTCTTGTCAGCAAAGGTCTAGCCACAGTGATCAGATACCGGCAGGATGATGACCAGAGATCATCACACT ACGATGAACTGCTTGCTGCAGAGGCCAGAGCTATTAAGAATGGCAAAGGATTGCATAGCAAGAAGGAAGTGCCTATCCACCGTGTTGCAG ATATATCTGGGGATACCCAAAAAGCAAAGCAGTTCCTGCCTTTTCTTCAGCGGGCAGGTCGTTCTGAAGCTGTGGTGGAATACGTCTTCA GTGGTTCTCGTCTCAAACTCTATTTGCCAAAGGAAACTTGCCTTATCACCTTCTTGCTTGCAGGTTTCCCTAGGACTTCTGCATGCCCAT GCCACACATATCCTGTGGCCCCCAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAA |
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FusionGenePPI for SND1_IMMP2L |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SND1 | IKBKE, SNW1, RBPJ, GTF2E2, GTF2E1, MYB, PIM1, STAT6, POLR2A, USP22, PDPK1, PRKAA1, UBA5, LZTR1, DHX9, CREBBP, RBM39, SIRT7, CUL3, CDK2, CAND1, APP, RPS3, HNRNPM, TOMM22, RPL19, MYBBP1A, SMNDC1, RPS20, NENF, RPL4, VDAC2, ILF2, SRSF3, HNRNPU, RPN1, HNRNPR, SSR3, FN1, VCAM1, CSNK2A1, ITGA4, G3BP1, PRPF8, RNU1-1, RNU2-1, RNU4-1, RNU6-1, RNU5A-1, MAK, TARDBP, EIF3CL, RPS11, RPS2, RPS6, RPS9, DDX3X, RPL23A, RPL35, RPS16, RPS26, RPS27, RPS3A, SHFM1, LIN28A, HUWE1, RAPGEF2, MDM2, CUL7, OBSL1, CCDC8, UBE2I, ESR1, MMP28, TDRD3, TXNDC5, NTRK1, NPM1, RPL10, CNOT1, MCM2, U2AF2, CDH1, PTP4A1, MTDH, PA2G4, TRAP1, ANXA5, SNRPB2, EIF5B, GPI, IDH2, PDIA3, UBE2N, MRPL12, CRNN, ZNF207, CPNE3, CS, PYGL, SF3A3, DNAJC8, PLS3, CPSF6, NANS, SF3A1, ECHS1, SRP68, MYL12B, AIMP1, CYLD, DLD, DLST, PDHA1, SOD1, TRIM25, BRCA1, YAP1 | IMMP2L | HNRNPD |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SND1_IMMP2L |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SND1_IMMP2L |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SND1 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Hgene | SND1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
| Tgene | IMMP2L | C0004352 | Autistic Disorder | 1 | CTD_human |
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