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Fusion gene ID: 34885 |
FusionGeneSummary for SMG1_ANO3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SMG1_ANO3 | Fusion gene ID: 34885 | Hgene | Tgene | Gene symbol | SMG1 | ANO3 | Gene ID | 23049 | 63982 |
| Gene name | SMG1, nonsense mediated mRNA decay associated PI3K related kinase | anoctamin 3 | |
| Synonyms | 61E3.4|ATX|LIP | C11orf25|DYT23|DYT24|GENX-3947|TMEM16C | |
| Cytomap | 16p12.3 | 11p14.3-p14.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein kinase SMG1PI-3-kinase-related kinase SMG-1SMG1 phosphatidylinositol 3-kinase-related kinaselambda-interacting proteinlambda/iota protein kinase C-interacting proteinsmg-1 homolog, phosphatidylinositol 3-kinase-related kinase | anoctamin-3transmembrane protein 16C (eight membrane-spanning domains) | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q96Q15 | Q9BYT9 | |
| Ensembl transtripts involved in fusion gene | ENST00000389467, ENST00000446231, ENST00000565224, ENST00000567737, | ENST00000537978, ENST00000525139, ENST00000256737, ENST00000531646, ENST00000531568, ENST00000529242, | |
| Fusion gene scores | * DoF score | 14 X 10 X 7=980 | 4 X 4 X 4=64 |
| # samples | 16 | 4 | |
| ** MAII score | log2(16/980*10)=-2.61470984411521 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SMG1 [Title/Abstract] AND ANO3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SMG1 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 11544179 |
| Hgene | SMG1 | GO:0018105 | peptidyl-serine phosphorylation | 11544179|15175154 |
| Hgene | SMG1 | GO:0046777 | protein autophosphorylation | 11331269|11544179 |
| Hgene | SMG1 | GO:0046854 | phosphatidylinositol phosphorylation | 11331269 |
| Hgene | SMG1 | GO:2001020 | regulation of response to DNA damage stimulus | 15175154 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A2-A0EY-01A | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000389467 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000389467 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000389467 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000389467 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000389467 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000389467 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000446231 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000446231 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| In-frame | ENST00000446231 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000446231 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000446231 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| 5CDS-intron | ENST00000446231 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000565224 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000565224 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000565224 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000565224 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000565224 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000565224 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000567737 | ENST00000537978 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000567737 | ENST00000525139 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-3CDS | ENST00000567737 | ENST00000256737 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000567737 | ENST00000531646 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000567737 | ENST00000531568 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
| intron-intron | ENST00000567737 | ENST00000529242 | SMG1 | chr16 | 18869492 | - | ANO3 | chr11 | 26669256 | + |
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FusionProtFeatures for SMG1_ANO3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SMG1 | ANO3 |
| Serine/threonine protein kinase involved in both mRNAsurveillance and genotoxic stress response pathways. Recognizesthe substrate consensus sequence [ST]-Q. Plays a central role innonsense-mediated decay (NMD) of mRNAs containing premature stopcodons by phosphorylating UPF1/RENT1. Recruited by release factorsto stalled ribosomes together with SMG8 and SMG9 (forming theSMG1C protein kinase complex), and UPF1 to form the transient SURF(SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURFcomplex associates with the exon junction complex (EJC) throughUPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillancecomplex which is believed to activate NMD. Also acts as agenotoxic stress-activated protein kinase that displays somefunctional overlap with ATM. Can phosphorylate p53/TP53 and isrequired for optimal p53/TP53 activation after cellular exposureto genotoxic stress. Its depletion leads to spontaneous DNA damageand increased sensitivity to ionizing radiation (IR). May activatePRKCI but not PRKCZ. {ECO:0000269|PubMed:11331269,ECO:0000269|PubMed:11544179, ECO:0000269|PubMed:15175154,ECO:0000269|PubMed:16452507}. | Has calcium-dependent phospholipid scramblase activity;scrambles phosphatidylcholine and galactosylceramide. Seems to actas potassium channel regulator and may inhibit pain signaling; canfacilitate KCNT1/Slack channel activity by promoting its fullsingle-channel conductance at very low sodium concentrations andby increasing its sodium sensitivity (By similarity). Does notexhibit calcium-activated chloride channel (CaCC) activity.{ECO:0000250|UniProtKB:A2AHL1, ECO:0000269|PubMed:21984732}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 832_914 | 809 | 982 | Topological domain | Extracellular |
| Tgene | >ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 936_981 | 809 | 982 | Topological domain | Cytoplasmic |
| Tgene | >ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 811_831 | 809 | 982 | Transmembrane | Helical |
| Tgene | >ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 915_935 | 809 | 982 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 1131_1866 | 1411 | 3662 | Domain | FAT |
| Hgene | >SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 2150_2478 | 1411 | 3662 | Domain | PI3K/PI4K |
| Hgene | >SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 3629_3661 | 1411 | 3662 | Domain | FATC |
| Hgene | >SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 1817_1852 | 1411 | 3662 | Repeat | Note=HEAT |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 1_403 | 809 | 982 | Topological domain | Cytoplasmic |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 425_469 | 809 | 982 | Topological domain | Extracellular |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 491_550 | 809 | 982 | Topological domain | Cytoplasmic |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 572_592 | 809 | 982 | Topological domain | Extracellular |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 614_640 | 809 | 982 | Topological domain | Cytoplasmic |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 662_761 | 809 | 982 | Topological domain | Extracellular |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 783_810 | 809 | 982 | Topological domain | Cytoplasmic |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 404_424 | 809 | 982 | Transmembrane | Helical |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 470_490 | 809 | 982 | Transmembrane | Helical |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 551_571 | 809 | 982 | Transmembrane | Helical |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 593_613 | 809 | 982 | Transmembrane | Helical |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 641_661 | 809 | 982 | Transmembrane | Helical |
| Tgene | ANO3 | chr16:18869492 | chr11:26669256 | ENST00000256737 | + | 22 | 27 | 762_782 | 809 | 982 | Transmembrane | Helical |
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FusionGeneSequence for SMG1_ANO3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000537978_chr11_26669256_+_1584aa MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSV NGGSGENTYGRKSLGQELRVNNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFS SVMQLVMTSLQSILENVDTPELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSE AVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIG MWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSG TRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENL EKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKT VLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLS TLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYI PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIK >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000525139_chr11_26669256_+_1584aa MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSV NGGSGENTYGRKSLGQELRVNNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFS SVMQLVMTSLQSILENVDTPELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSE AVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIG MWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSG TRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENL EKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKT VLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLS TLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYI PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIK >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000256737_chr11_26669256_+_1584aa MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSV NGGSGENTYGRKSLGQELRVNNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFS SVMQLVMTSLQSILENVDTPELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSE AVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIG MWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSG TRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENL EKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKT VLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLS TLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYI PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIK >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000537978_chr11_26669256_+_1584aa MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSV NGGSGENTYGRKSLGQELRVNNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFS SVMQLVMTSLQSILENVDTPELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSE AVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIG MWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSG TRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENL EKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKT VLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLS TLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYI PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIK >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000525139_chr11_26669256_+_1584aa MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSV NGGSGENTYGRKSLGQELRVNNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFS SVMQLVMTSLQSILENVDTPELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSE AVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIG MWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSG TRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENL EKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKT VLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLS TLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYI PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIK >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000256737_chr11_26669256_+_1584aa MSRRAPGSRLSSGGGGGGTKYPRSWNDWQPRTDSASADPDNLKYSSSRDRGGSSSYGLQPSNSAVVSRQRHDDTRVHADIQNDEKGGYSV NGGSGENTYGRKSLGQELRVNNVTSPEFTSVQHGSRALATKDMRKSQERSMSYSDESRLSNLLRRITREDDRDRRLATVKQLKEFIQQPE NKLVLVKQLDNILAAVHDVLNESSKLLQELRQEGACCLGLLCASLSYEAEKIFKWIFSKFSSSAKDEVKLLYLCATYKALETVGEKKAFS SVMQLVMTSLQSILENVDTPELLCKCVKCILLVARCYPHIFSTNFRDTVDILVGWHIDHTQKPSLTQQVSGWLQSLEPFWVADLAFSTTL LGQFLEDMEAYAEDLSHVASGESVDEDVPPPSVSLPKLAALLRVFSTVVRSIGERFSPIRGPPITEAYVTDVLYRVMRCVTAANQVFFSE AVLTAANECVGVLLGSLDPSMTIHCDMVITYGLDQLENCQTCGTDYIISVLNLLTLIVEQINTKLPSSFVEKLFIPSSKLLFLRYHKEKE VVAVAHAVYQAVLSLKNIPVLETAYKLILGEMTCALNNLLHSLQLPEACSEIKHEAFKNHVFNVDNAKFVVIFDLSALTTIGNAKNSLIG MWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATKKHFSIILNLLGILLKK DNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSG TRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQST IPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENL EKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEAL CELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGRNSASPKHSLNGESRKT VLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVECTEQLELLPGENINLL AGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLS TLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKGIWLGILEGIGILAVITNAFVIAITSDYI PRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000537978_chr11_26669256_+_4752nt ATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCC AGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCT TCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTC AATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGT GTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCG AATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAA AATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTG AGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTT AGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCA TCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATT CTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACT CAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTT CTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCT CCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGG GGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAG GCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACA TATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAG ATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAG GTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGA GAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCAT GTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGG ATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATT CAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTG TTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAA GATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCT TTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGC AGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGA ACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAA ATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTG TATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACA ATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGA ACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGAT GTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTG GAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGC CAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACAT GGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTA TGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTG GCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCC AGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACT GTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGG GCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTAT ATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTT GCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAA GTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTG GTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGT ACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAA GCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATT AAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATC CCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGC CTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAA CCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAG TCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTAT >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000525139_chr11_26669256_+_4752nt ATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCC AGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCT TCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTC AATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGT GTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCG AATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAA AATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTG AGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTT AGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCA TCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATT CTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACT CAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTT CTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCT CCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGG GGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAG GCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACA TATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAG ATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAG GTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGA GAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCAT GTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGG ATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATT CAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTG TTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAA GATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCT TTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGC AGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGA ACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAA ATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTG TATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACA ATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGA ACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGAT GTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTG GAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGC CAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACAT GGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTA TGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTG GCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCC AGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACT GTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGG GCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTAT ATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTT GCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAA GTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTG GTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGT ACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAA GCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATT AAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATC CCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGC CTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAA CCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAG TCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTAT >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000256737_chr11_26669256_+_4752nt ATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCC AGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCT TCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTC AATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGT GTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCG AATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAA AATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTG AGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTT AGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCA TCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATT CTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACT CAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTT CTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCT CCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGG GGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAG GCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACA TATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAG ATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAG GTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGA GAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCAT GTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGG ATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATT CAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTG TTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAA GATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCT TTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGC AGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGA ACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAA ATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTG TATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACA ATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGA ACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGAT GTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTG GAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGC CAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACAT GGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTA TGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTG GCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCC AGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACT GTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGG GCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTAT ATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTT GCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAA GTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTG GTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGT ACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAA GCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATT AAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATC CCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGC CTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAA CCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAG TCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTAT >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000537978_chr11_26669256_+_4752nt ATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCC AGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCT TCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTC AATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGT GTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCG AATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAA AATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTG AGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTT AGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCA TCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATT CTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACT CAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTT CTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCT CCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGG GGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAG GCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACA TATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAG ATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAG GTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGA GAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCAT GTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGG ATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATT CAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTG TTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAA GATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCT TTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGC AGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGA ACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAA ATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTG TATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACA ATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGA ACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGAT GTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTG GAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGC CAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACAT GGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTA TGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTG GCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCC AGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACT GTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGG GCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTAT ATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTT GCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAA GTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTG GTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGT ACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAA GCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATT AAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATC CCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGC CTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAA CCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAG TCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTAT >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000525139_chr11_26669256_+_4752nt ATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCC AGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCT TCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTC AATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGT GTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCG AATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAA AATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTG AGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTT AGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCA TCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATT CTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACT CAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTT CTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCT CCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGG GGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAG GCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACA TATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAG ATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAG GTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGA GAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCAT GTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGG ATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATT CAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTG TTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAA GATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCT TTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGC AGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGA ACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAA ATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTG TATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACA ATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGA ACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGAT GTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTG GAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGC CAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACAT GGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTA TGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTG GCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCC AGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACT GTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGG GCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTAT ATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTT GCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAA GTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTG GTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGT ACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAA GCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATT AAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATC CCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGC CTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAA CCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAG TCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTAT >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000256737_chr11_26669256_+_4752nt ATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCC AGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCT TCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTC AATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGT GTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCG AATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAA AATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTG AGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTT AGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCA TCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATT CTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACT CAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTT CTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCT CCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGG GGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAG GCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACA TATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAG ATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAG GTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGA GAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCAT GTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGG ATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATT CAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTG TTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAA GATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCT TTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGC AGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGA ACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAA ATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTG TATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACA ATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGA ACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGAT GTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTG GAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGC CAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACAT GGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTA TGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTG GCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCC AGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACT GTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGG GCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTAT ATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTT GCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAA GTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTG GTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGT ACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAA GCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATT AAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATC CCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGC CTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAA CCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAG TCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000537978_chr11_26669256_+_5351nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000525139_chr11_26669256_+_5351nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC >In-frame_SMG1_ENST00000389467_chr16_18869492_-_ANO3_ENST00000256737_chr11_26669256_+_7959nt GCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCTCGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCT GGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCACCGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCG GAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCCTTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCC GGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGCGACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAG GTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCGGCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAA CCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAAAATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAA CCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATGATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGT GTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGTCGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACC AGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACATGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTG TCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAGACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCA GAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCTTGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAG TTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTGCTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAA TTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACTTATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTT TCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTATTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGC ATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCACTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCAT ACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGTTGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACT CTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTGAGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCT CCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCCGGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATT CGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTCTGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCT GAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTTTGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATT ACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTGGTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAA CAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAACTGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAA GAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGCTCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTG GGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTCTACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAAT CATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATATTTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATA GGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCC ATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCT TTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAG AAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCA CCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCA TGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGT GGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAA GAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATT TTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCA ACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTG AGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAG GATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAAT CTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAAT CGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGA CATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCA TTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCA GTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATC TCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAA ACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGAT TGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAAC TATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTA CTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATT GAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAAT GTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTA AGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGT GAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAA ATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTATATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTAC ATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTGCAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAAT AGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAAAATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCC AAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTGCTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATT AAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGGGTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATG TATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAAAAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACC CATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAACTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACA TGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCTGGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGAC CTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATGTAATTCTCAGAACCAGTCTCAGGGAGATATATGCTTGGAGAACTCTGCCT TCCATCAACTGCAGTGTAATGGGAAAGAGGGTGGTGAGGTTTTGAAAGACAGATTTCCATGTAAATGTGCACAAGCCAGGCATGGCTTAA AATATCATGCAGTCTTCACTCACATACTAATTTGACTTTGGAAAGTATGGTTGAGTTCAGATACTTATAAGAAATGACTTAAACAAATCC TTGCCTTGGCTGCCAGAACTCTACATCCCTTCAGTTTACAGGTTGGTAGGAATTGCCCATGTCTCTTGCTGAGATTATGGATCTGTGCCA CAGGGGATTTATGCTGCTTTACATTGACTATGCAGTTGAAGAGTTGCACATCACCTTTAGTAGTCAAACCAAAAATCTAAGATTCCAAAA AGAACAGCATTCATTGAAATAATATTCCATTGCATTGGCTACTTCAAGTCTCTTTTACCCCTGGCAGAGCCAGTTGCAGTGCAATTTTTT GTACTAAATGCCAATAAAGCCACATACTTATAAACTATGAATGGCTATTCTTATATAGTTTAGAACACAACTAATCCATACTTTATTGTG GAAGGCTGTTTTATAGTTTATTTAATTTTTTCTCTATGATTTATTACAACTCTCACGGAATATTAACTTGAAATGCTGTAAATACGTTGG TTTTCCTTGTCCCTTTGCACCTTGACAGTACGTAGTATACATTGTGGTTTATGCAGCTCTGACACCAGTTTTTGCTATTGTAATATGTTT ATTCGGGAAAACTGAGGCCAGATGCTCTGCAACACTTACGCTTTTTCAACAATGTGCACTCTTACTCATGAACTAATGAAAATAATGCAT GAATATAAATCTATATTATTTGCTAAAAAAAGAAAAAACATTTGTGTTTTAGTTTCTTTTTTCATGACTGAAGGGAGTTTTATGTTATTA TTTCTTCCATAGTTTTGTTTTGGTTTATTTTTAACAACGCTCTAGAAACAAAGTCAAATTAATCACAAAAGACATAATTTTGCTTTGTTG TGGAATTTCTATTTCAACGTCAACTCTGTATCTATGAGTATGTCTGTTCCACAGACAGATGAGGCAGGAGTGATGGGGCACTCAAGAAAG TTCAGAGGAGGCATAAGCTATGGAGGTTGGAAAGGAAGAAAGAGAAGAGCTGAAGTAAATGTATGGTAGAAATTAAGACGTTTCTTTGCA AAACAAGGAAATCACACATATGCACACATACATATTTATGGTTACTATGATTGTTATTATTTGTCCAATCAAGCAAAGCACCATTATTTC TAACATATAAAAGACCAGATCAAACACAATGGAAATAAAGCTACTACATATATATGCCAGTATTTCTCTAGTAAGATTATGTTTCTCTTA CTAGAAAACTATTTTCTAAATATTAACACTGAAAATGTTTTGTTAGCTTTTCCTTCTTTCTCTCCAGAAGAAACATGGATAGATGATAGC TGTTTCATTGTTTGTTTTTGTCAAGCATATTCACTTTCCTCCTTGTCCTCTGATTCTGAGCAAAGGGCCTCAGACTCTGAACTTCCCTCA AGTGCCGTTGTTATGTGAAACTCTTCCATTCAGATTCCAGAGAGGTTCTCATGCTCCCCCCCCTCCTTATTTGTAGCAATCGTAGCAACT AATTCCACTAAGTACAAGGGAGTTTTTTACACTCCTCCATTTTTATAGCATCTGCATTTCTTTTTCTTTGTTAGGTACATGTATACACCT GCCTGAGTATAAATACTCTCTCTACCTAATAATAACATCAACCAACATCTTTTCCAAATTAGGGCCACAGAACAGCAACATTTGTCTGAC AGTAGTATAAAGAATAATGATAGCTCTATCCTTAAGAAGTATTTCCTTTCCTTTTTATATAGTCCCGTTAGGGTTTAAAACCATATTGAT CAACTAGAAAGAAAAATATGAAAAGAGAAAAATATTTTAATTTAAAAATTGTAATACATTGATTTATAAAATGCCTTCTCTGATACTTTT GAAACAGATGTGAAAAACAGAAAAAGAAAAAATTGTCTGAAATGTTTATTTTGCAAAACAGTGCAATAGAATCTAGTTATGCCTTCATCA CTGTTGACAGTAAATACTGACAGCCCCTTGCAGTGTGTTAGTTTTAGATCACTCTGTTTTAGTTGAGAGAAATGTTTTATATCATGGTTT TTATATGAATACAAATTATTTCTCAAAGATTTATAGCACACACTATTCTCAGGAATTCTGTATTACATGAATGCTGCTTATATATTTTCA TATTCTAACTTGTCTTTTCAAGCAAATAACTAATATATATGTGCATGCAGTCTGCCTTGACAAGTTGTTCCAAGCTGAAGAGCTTTCACT GTACAATGTGTGGAAAATCACCATAGATCATGGCTGAAATAGTTTGTAATTGTCTGAGTCTGTGCACGTACTTTTAGATAAAATGCTGCT GAGTGACTGCATGATGAGATACAACTTCTGAATGCTGCACATTCTTCCAAAATGATCCTTAGCACAATCTATTGTATGATGGAATGAATA >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000537978_chr11_26669256_+_5401nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000525139_chr11_26669256_+_5401nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG >In-frame_SMG1_ENST00000446231_chr16_18869492_-_ANO3_ENST00000256737_chr11_26669256_+_8009nt GTGCGACAGCGGCGGCGCGGCGGGCGGAGCCGGGAGGCGGGGAAGCAGTGGCCGTGTGAGCGTGAGGAGCTGCCGCCACCGCCTGCTCCT CGTCGTCCTCGTCCTCCGGGGCCCCGGCGACGTGGGCCGCGCACGGCCCTGGAAAAGACGTCGCCTCCCCTTCATCCGCCTCTCTCTCAC CGCGCCGCTCCCGCCTCCTCGTCCTGCGCTGCGGGCTCAGGCGGAACCCGGAACGGCCGTCCTCTTCCCCCGCCCTCCGCCGCCTCCTCC TTCTCCTCCTCCTCCTCCTCCTCCTCCTTCTCGGCTTCCTCCTCAGCCCCGGGCCGGAGCGGGGTGTCGGCGGCGGCCGGTTCGGGCGGC GACTCGCGCTTCTTTGGGCGGCGGCGCTTGGCCATGTCGTGTCGGGGAAGGTAATGAGCCGCAGAGCCCCGGGGTCTCGGCTGAGCAGCG GCGGCGGCGGCGGCGGCACCAAGTATCCGCGGAGCTGGAATGACTGGCAACCCAGAACTGATAGTGCATCAGCCGACCCAGATAATTTAA AATATTCTTCATCCAGAGATAGAGGTGGTTCTTCCTCTTATGGACTGCAACCTTCAAATTCAGCTGTGGTGTCTCGGCAAAGGCACGATG ATACCAGAGTCCACGCTGACATACAGAATGACGAAAAGGGTGGCTACAGTGTCAATGGAGGATCTGGGGAAAATACTTATGGTCGGAAGT CGTTGGGGCAAGAGCTGAGGGTTAACAATGTGACCAGCCCTGAGTTCACCAGTGTTCAGCATGGCAGTCGTGCTTTAGCCACCAAAGACA TGAGGAAATCACAGGAGAGATCGATGTCTTATTCTGATGAGTCTCGACTGTCGAATCTTCTTCGGAGGATCACCCGGGAAGACGACAGAG ACCGAAGATTGGCTACTGTAAAGCAGTTGAAAGAATTTATTCAGCAACCAGAAAATAAGCTGGTACTAGTTAAACAATTGGATAATATCT TGGCTGCTGTACATGACGTGCTTAATGAAAGTAGCAAATTGCTTCAGGAGTTGAGACAGGAGGGAGCTTGCTGTCTTGGCCTTCTTTGTG CTTCTCTGAGCTATGAGGCTGAGAAGATCTTCAAGTGGATTTTTAGCAAATTTAGCTCATCTGCAAAAGATGAAGTTAAACTCCTCTACT TATGTGCCACCTACAAAGCACTAGAGACTGTAGGAGAAAAGAAAGCCTTTTCATCTGTAATGCAGCTTGTAATGACCAGCCTGCAGTCTA TTCTTGAAAATGTGGATACACCAGAATTGCTTTGTAAATGTGTTAAGTGCATTCTTTTGGTGGCTCGATGTTACCCTCATATTTTCAGCA CTAATTTTAGGGATACAGTTGATATATTAGTTGGATGGCATATAGATCATACTCAGAAACCTTCGCTCACGCAGCAGGTATCTGGGTGGT TGCAGAGTTTGGAGCCATTTTGGGTAGCTGATCTTGCATTTTCTACTACTCTTCTTGGTCAGTTTCTGGAAGACATGGAAGCATATGCTG AGGACCTCAGCCATGTGGCCTCTGGGGAATCAGTGGATGAAGATGTCCCTCCTCCATCAGTGTCATTACCAAAGCTGGCTGCACTTCTCC GGGTATTTAGTACTGTGGTGAGGAGCATTGGGGAACGCTTCAGCCCAATTCGGGGTCCTCCAATTACTGAGGCATATGTAACAGATGTTC TGTACAGAGTAATGAGATGTGTGACGGCTGCAAACCAGGTGTTTTTTTCTGAGGCTGTGTTGACAGCTGCTAATGAGTGTGTTGGTGTTT TGCTCGGCAGCTTGGATCCTAGCATGACTATACATTGTGACATGGTCATTACATATGGATTAGACCAACTGGAGAATTGCCAGACTTGTG GTACCGATTATATCATCTCAGTCTTGAATTTACTCACGCTGATTGTTGAACAGATAAATACGAAACTGCCATCATCATTTGTAGAAAAAC TGTTTATACCATCATCTAAACTACTATTCTTGCGTTATCATAAAGAAAAAGAGGTTGTTGCTGTAGCCCATGCTGTTTATCAAGCAGTGC TCAGCTTGAAGAATATTCCTGTTTTGGAGACTGCCTATAAGTTAATATTGGGAGAAATGACTTGTGCCCTAAACAACCTCCTACACAGTC TACAACTTCCTGAGGCCTGTTCTGAAATAAAACATGAGGCTTTTAAGAATCATGTGTTCAATGTAGACAATGCAAAATTTGTAGTTATAT TTGACCTCAGTGCCCTGACTACAATTGGAAATGCCAAAAACTCACTAATAGGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGA GTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTA CCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTA CAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGA CTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAG GCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATG ATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAAT CAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCAC CAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGT TGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTT GGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAA TTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCC ATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTA ATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCT CCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCC TATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTG CTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTG TGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTG GGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTA TAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACT TGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTG TTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAAC TGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTG CTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTG GACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACA CAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCAT GGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGGTATCTGGCTTGGAATTCTCGAAGGAATCGGTA TATTGGCTGTGATCACCAATGCATTTGTAATTGCTATTACTTCTGATTACATCCCACGTTTTGTTTATGAATACAAATATGGCCCCTGTG CAAATCATGTAGAACCAAGTGAAAATTGCTTGAAGGGATATGTCAACAATAGCCTATCCTTCTTTGACCTGAGTGAGCTTGGTATGGGAA AATCTGGTTATTGCAGGTACAGAGACTACAGAGGCCCGCCCTGGAGTTCCAAACCCTATGAGTTTACTTTACAATACTGGCATATCCTTG CTGCTAGATTGGCCTTCATTATTGTGTTTGAGCACCTTGTTTTTGGGATTAAGTCATTCATCGCATACCTGATTCCAGACGTACCAAAGG GTCTACATGACCGAATACGACGAGAGAAGTACTTAGTTCAAGAAATGATGTATGAGGCTGAACTGGAACATTTGCAACAACAACGGAGAA AAAGTGGTCAGCCTGTTCACCATGAATGGCCTTAGTTGACACCTGTTACCCATTAGGGGTGATAACATTAATGGGAAGAAATGATGGCAA CTTTGAATGCTAGGTGAAATCTAGGAGGAAGGCATACTTGGCAAACCACATGTATAATATGCTACTTGGAAATGTATCACAGCCATCTCT GGGATTTGAAATATCCAGACTTGTAGGGAAGAAAACAATGACTTGACGACCTTAAAAAGGGTTAGATTGACATTGCAGGAAGCCAGGATG TAATTCTCAGAACCAGTCTCAGGGAGATATATGCTTGGAGAACTCTGCCTTCCATCAACTGCAGTGTAATGGGAAAGAGGGTGGTGAGGT TTTGAAAGACAGATTTCCATGTAAATGTGCACAAGCCAGGCATGGCTTAAAATATCATGCAGTCTTCACTCACATACTAATTTGACTTTG GAAAGTATGGTTGAGTTCAGATACTTATAAGAAATGACTTAAACAAATCCTTGCCTTGGCTGCCAGAACTCTACATCCCTTCAGTTTACA GGTTGGTAGGAATTGCCCATGTCTCTTGCTGAGATTATGGATCTGTGCCACAGGGGATTTATGCTGCTTTACATTGACTATGCAGTTGAA GAGTTGCACATCACCTTTAGTAGTCAAACCAAAAATCTAAGATTCCAAAAAGAACAGCATTCATTGAAATAATATTCCATTGCATTGGCT ACTTCAAGTCTCTTTTACCCCTGGCAGAGCCAGTTGCAGTGCAATTTTTTGTACTAAATGCCAATAAAGCCACATACTTATAAACTATGA ATGGCTATTCTTATATAGTTTAGAACACAACTAATCCATACTTTATTGTGGAAGGCTGTTTTATAGTTTATTTAATTTTTTCTCTATGAT TTATTACAACTCTCACGGAATATTAACTTGAAATGCTGTAAATACGTTGGTTTTCCTTGTCCCTTTGCACCTTGACAGTACGTAGTATAC ATTGTGGTTTATGCAGCTCTGACACCAGTTTTTGCTATTGTAATATGTTTATTCGGGAAAACTGAGGCCAGATGCTCTGCAACACTTACG CTTTTTCAACAATGTGCACTCTTACTCATGAACTAATGAAAATAATGCATGAATATAAATCTATATTATTTGCTAAAAAAAGAAAAAACA TTTGTGTTTTAGTTTCTTTTTTCATGACTGAAGGGAGTTTTATGTTATTATTTCTTCCATAGTTTTGTTTTGGTTTATTTTTAACAACGC TCTAGAAACAAAGTCAAATTAATCACAAAAGACATAATTTTGCTTTGTTGTGGAATTTCTATTTCAACGTCAACTCTGTATCTATGAGTA TGTCTGTTCCACAGACAGATGAGGCAGGAGTGATGGGGCACTCAAGAAAGTTCAGAGGAGGCATAAGCTATGGAGGTTGGAAAGGAAGAA AGAGAAGAGCTGAAGTAAATGTATGGTAGAAATTAAGACGTTTCTTTGCAAAACAAGGAAATCACACATATGCACACATACATATTTATG GTTACTATGATTGTTATTATTTGTCCAATCAAGCAAAGCACCATTATTTCTAACATATAAAAGACCAGATCAAACACAATGGAAATAAAG CTACTACATATATATGCCAGTATTTCTCTAGTAAGATTATGTTTCTCTTACTAGAAAACTATTTTCTAAATATTAACACTGAAAATGTTT TGTTAGCTTTTCCTTCTTTCTCTCCAGAAGAAACATGGATAGATGATAGCTGTTTCATTGTTTGTTTTTGTCAAGCATATTCACTTTCCT CCTTGTCCTCTGATTCTGAGCAAAGGGCCTCAGACTCTGAACTTCCCTCAAGTGCCGTTGTTATGTGAAACTCTTCCATTCAGATTCCAG AGAGGTTCTCATGCTCCCCCCCCTCCTTATTTGTAGCAATCGTAGCAACTAATTCCACTAAGTACAAGGGAGTTTTTTACACTCCTCCAT TTTTATAGCATCTGCATTTCTTTTTCTTTGTTAGGTACATGTATACACCTGCCTGAGTATAAATACTCTCTCTACCTAATAATAACATCA ACCAACATCTTTTCCAAATTAGGGCCACAGAACAGCAACATTTGTCTGACAGTAGTATAAAGAATAATGATAGCTCTATCCTTAAGAAGT ATTTCCTTTCCTTTTTATATAGTCCCGTTAGGGTTTAAAACCATATTGATCAACTAGAAAGAAAAATATGAAAAGAGAAAAATATTTTAA TTTAAAAATTGTAATACATTGATTTATAAAATGCCTTCTCTGATACTTTTGAAACAGATGTGAAAAACAGAAAAAGAAAAAATTGTCTGA AATGTTTATTTTGCAAAACAGTGCAATAGAATCTAGTTATGCCTTCATCACTGTTGACAGTAAATACTGACAGCCCCTTGCAGTGTGTTA GTTTTAGATCACTCTGTTTTAGTTGAGAGAAATGTTTTATATCATGGTTTTTATATGAATACAAATTATTTCTCAAAGATTTATAGCACA CACTATTCTCAGGAATTCTGTATTACATGAATGCTGCTTATATATTTTCATATTCTAACTTGTCTTTTCAAGCAAATAACTAATATATAT GTGCATGCAGTCTGCCTTGACAAGTTGTTCCAAGCTGAAGAGCTTTCACTGTACAATGTGTGGAAAATCACCATAGATCATGGCTGAAAT AGTTTGTAATTGTCTGAGTCTGTGCACGTACTTTTAGATAAAATGCTGCTGAGTGACTGCATGATGAGATACAACTTCTGAATGCTGCAC |
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FusionGenePPI for SMG1_ANO3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SMG1 | PRKCI, SMG1, UPF1, UPF2, UPF3A, TTI1, TELO2, ELAVL1, SMG8, SMG9, RBM8A, UPF3B, NCBP2, PABPC1, SMG7, EIF4A3, MAGOH, GSPT2, GSPT1, EEF2, HSP90AA1, HSPA4, RUVBL1, RUVBL2, POLR2E, TUBA1A, TUBG1, HAUS2, HTR6, HSP90B1, EGFR, EPHA1 | ANO3 | HSPA5, SNX3, CTR9, RAPGEF2, RGMA, ASPM |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | SMG1 | chr16:18869492 | chr11:26669256 | ENST00000446231 | - | 29 | 63 | 1_1977 | 1411 | 3662 | SMG8 and SMG9 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SMG1_ANO3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SMG1_ANO3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ANO3 | C0009952 | Febrile Convulsions | 1 | CTD_human |
| Tgene | ANO3 | C3554374 | DYSTONIA 24 | 1 | ORPHANET;UNIPROT |
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