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Fusion gene ID: 34822 |
FusionGeneSummary for SMARCC1_DOCK3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SMARCC1_DOCK3 | Fusion gene ID: 34822 | Hgene | Tgene | Gene symbol | SMARCC1 | DOCK3 | Gene ID | 6599 | 1795 |
| Gene name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 | dedicator of cytokinesis 3 | |
| Synonyms | BAF155|CRACC1|Rsc8|SRG3|SWI3 | MOCA|PBP | |
| Cytomap | 3p21.31 | 3p21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | SWI/SNF complex subunit SMARCC1BRG1-associated factor 155SWI/SNF complex 155 kDa subunitSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1chromatin remodeling complex BAF155 subunitmammalian chromatin remode | dedicator of cytokinesis protein 3modifier of cell adhesionpresenilin-binding protein | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q92922 | Q8IZD9 | |
| Ensembl transtripts involved in fusion gene | ENST00000254480, ENST00000425518, | ENST00000266037, | |
| Fusion gene scores | * DoF score | 13 X 10 X 9=1170 | 5 X 4 X 4=80 |
| # samples | 17 | 5 | |
| ** MAII score | log2(17/1170*10)=-2.78290187833307 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SMARCC1 [Title/Abstract] AND DOCK3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. DDR (DNA damage repair) gene involved fusion gene, retained protein feature but frameshift. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SMARCC1 | GO:0006337 | nucleosome disassembly | 8895581 |
| Hgene | SMARCC1 | GO:0006338 | chromatin remodeling | 10078207|11018012|11726552 |
| Hgene | SMARCC1 | GO:0045893 | positive regulation of transcription, DNA-templated | 11018012 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-BL-A3JM-01A | SMARCC1 | chr3 | 47814307 | - | DOCK3 | chr3 | 50927457 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000254480 | ENST00000266037 | SMARCC1 | chr3 | 47814307 | - | DOCK3 | chr3 | 50927457 | + |
| 5UTR-3CDS | ENST00000425518 | ENST00000266037 | SMARCC1 | chr3 | 47814307 | - | DOCK3 | chr3 | 50927457 | + |
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FusionProtFeatures for SMARCC1_DOCK3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SMARCC1 | DOCK3 |
| Involved in transcriptional activation and repression ofselect genes by chromatin remodeling (alteration of DNA-nucleosometopology). Component of SWI/SNF chromatin remodeling complexesthat carry out key enzymatic activities, changing chromatinstructure by altering DNA-histone contacts within a nucleosome inan ATP-dependent manner. May stimulate the ATPase activity of thecatalytic subunit of the complex (PubMed:10078207). Belongs to theneural progenitors-specific chromatin remodeling complex (npBAFcomplex) and the neuron-specific chromatin remodeling complex(nBAF complex). During neural development a switch from astem/progenitor to a postmitotic chromatin remodeling mechanismoccurs as neurons exit the cell cycle and become committed totheir adult state. The transition from proliferating neuralstem/progenitor cells to postmitotic neurons requires a switch insubunit composition of the npBAF and nBAF complexes. As neuralprogenitors exit mitosis and differentiate into neurons, npBAFcomplexes which contain ACTL6A/BAF53A and PHF10/BAF45A, areexchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45Bor DPF3/BAF45C subunits in neuron-specific complexes (nBAF). ThenpBAF complex is essential for the self-renewal/proliferativecapacity of the multipotent neural stem cells. The nBAF complexalong with CREST plays a role regulating the activity of genesessential for dendrite growth (By similarity).{ECO:0000250|UniProtKB:P97496, ECO:0000269|PubMed:10078207,ECO:0000269|PubMed:11018012, ECO:0000303|PubMed:22952240,ECO:0000303|PubMed:26601204}. | Potential guanine nucleotide exchange factor (GEF). GEFproteins activate some small GTPases by exchanging bound GDP forfree GTP. Its interaction with presenilin proteins as well as itsability to stimulate Tau/MAPT phosphorylation suggest that it maybe involved in Alzheimer disease. Ectopic expression in nervecells decreases the secretion of amyloid-beta APBA1 protein andlowers the rate of cell-substratum adhesion, suggesting that itmay affect the function of some small GTPase involved in theregulation of actin cytoskeleton or cell adhesion receptors (Bysimilarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >DOCK3 | chr3:47814307 | chr3:50927457 | ENST00000266037 | + | 2 | 53 | 1731_1768 | 54 | 2031 | Compositional bias | Note=Ser-rich |
| Tgene | >DOCK3 | chr3:47814307 | chr3:50927457 | ENST00000266037 | + | 2 | 53 | 1228_1635 | 54 | 2031 | Domain | DHR-2 |
| Tgene | >DOCK3 | chr3:47814307 | chr3:50927457 | ENST00000266037 | + | 2 | 53 | 421_599 | 54 | 2031 | Domain | DHR-1 |
| Tgene | >DOCK3 | chr3:47814307 | chr3:50927457 | ENST00000266037 | + | 2 | 53 | 1970_1976 | 54 | 2031 | Motif | SH3-binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SMARCC1 | chr3:47814307 | chr3:50927457 | ENST00000254480 | - | 2 | 28 | 914_946 | 105 | 1106 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >SMARCC1 | chr3:47814307 | chr3:50927457 | ENST00000254480 | - | 2 | 28 | 329_336 | 105 | 1106 | Compositional bias | Note=Poly-Pro |
| Hgene | >SMARCC1 | chr3:47814307 | chr3:50927457 | ENST00000254480 | - | 2 | 28 | 769_863 | 105 | 1106 | Compositional bias | Note=Glu-rich |
| Hgene | >SMARCC1 | chr3:47814307 | chr3:50927457 | ENST00000254480 | - | 2 | 28 | 867_878 | 105 | 1106 | Compositional bias | Note=Poly-Ala |
| Hgene | >SMARCC1 | chr3:47814307 | chr3:50927457 | ENST00000254480 | - | 2 | 28 | 977_1105 | 105 | 1106 | Compositional bias | Note=Pro-rich |
| Hgene | >SMARCC1 | chr3:47814307 | chr3:50927457 | ENST00000254480 | - | 2 | 28 | 449_546 | 105 | 1106 | Domain | SWIRM |
| Hgene | >SMARCC1 | chr3:47814307 | chr3:50927457 | ENST00000254480 | - | 2 | 28 | 618_669 | 105 | 1106 | Domain | SANT |
| Tgene | DOCK3 | chr3:47814307 | chr3:50927457 | ENST00000266037 | + | 2 | 53 | 6_67 | 54 | 2031 | Domain | SH3 |
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FusionGeneSequence for SMARCC1_DOCK3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SMARCC1_ENST00000254480_chr3_47814307_-_DOCK3_ENST00000266037_chr3_50927457_+_2082aa MAAAAGGGGPGTAVGATGSGIAAAAAGLAVYRRKDGGPATKFWESPETVSQLDSVRVWLGKHYKKYVHADAPTNKTLAGLVVQLLQFQED AFGKHVTNPAFTKLPGIFPANYIHLKKAIVSNRGQYETVVPLEDSIVTEVTATLQEWASLWKQLYVKHKVDLFYKLRHVMNELIDLRRQL LSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGETCRMPVPHHFFL SLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPP HLHYRRPYGCAVLSILDVLQSLTEVKEEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYSAPSASHGLIISLQLLRGDMEQIRRENPMIF NRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWGE IIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIP SSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDDNTEKYGLLVFQSLVF IINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSS IQELFQSIRFVLSLDSRNSETLLFTQAALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFS ESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAE ITGEYVSCLLSLLRQMCDTHFQHLLDNFQSKDELKEFLLKIFCVFRNLMKMSVFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFTETDFD FKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFH DMMDWEQRKNGNFKQVEAELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGISFVTSVTRLMERLLDYRDCMKG EETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWEDRPLREFLHYPSQTEWQRKEGLCRKIIH YFNKGKSWEFGIPLCRELACQYESLYDYQSLSWIRKMEASYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQR MLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVLQMDRVPDRVKSFYRVNNVRKFRYDRPFHKGPKDKENEFKSLWIERT TLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRSLISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYI NKHPGDAEKITQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEFPGLDKLSPACSGTSTPRGNVLASHSPMSP ESIKMTHRHSPMNLMGTGRHSSSSLSSHASSEAGNMVMLGDGSMGDAPEDLYHHMQLAYPNPRYQGSVTNVSVLSSSQASPSSSSLSSTH SAPSQMITSAPSSARGSPSLPDKYRHAREMMLLLPTYRDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKPCSDPNLSVAEKGHYSLH FDAFHHPLGDTPPALPARTLRKSPLHPIPASPTSPQSGLDGSNSTLSGSASSGVSSLSESNFGHSSEAPPRTDTMDSMPSQAWNADEDLE PPYLPVHYSLSESAVLDSIKAQPCRSHSAPGCVIPQDPMDPPALPPKPYHPRLPALEHDEGVLLREETERPRGLHRKAPLPPGSAKEEQA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SMARCC1_ENST00000254480_chr3_47814307_-_DOCK3_ENST00000266037_chr3_50927457_+_6246nt ATGGCCGCAGCGGCGGGCGGCGGCGGGCCGGGGACAGCGGTAGGCGCCACGGGCTCGGGGATTGCGGCGGCAGCCGCAGGCCTAGCTGTT TATCGACGGAAGGATGGGGGCCCGGCCACCAAGTTTTGGGAGAGCCCGGAGACGGTGTCCCAGCTGGATTCGGTGCGGGTCTGGCTGGGC AAGCACTACAAGAAGTATGTTCATGCGGATGCTCCTACCAATAAAACACTGGCTGGGCTGGTGGTGCAGCTTCTTCAGTTCCAGGAAGAT GCCTTTGGGAAGCATGTCACCAACCCGGCCTTCACCAAACTCCCTGGGATCTTTCCTGCAAATTACATTCACTTGAAAAAGGCAATTGTC AGTAATAGGGGGCAGTATGAAACTGTGGTTCCACTTGAAGATTCTATTGTGACTGAGGTTACAGCAACTCTACAAGAATGGGCAAGTTTG TGGAAACAGTTGTATGTGAAACACAAAGTAGATCTTTTCTACAAACTACGCCATGTGATGAATGAACTTATTGACCTGCGAAGGCAGCTA CTGTCTGGTCACCTGACTCAGGATCAGGTGCGGGAGGTTAAGCGGCACATCACCGTGCGCCTGGACTGGGGTAATGAACATTTGGGCCTG GACCTGGTGCCTCGGAAGGACTTTGAAGTAGTGGACTCGGACCAGATTAGTGTCTCAGATCTCTATAAGATGCATTTATCTAGCCGGCAG AGTGTACAGCAAAGCACATCCCAGGTAGATACAATGCGCCCACGTCATGGGGAAACATGTCGGATGCCAGTGCCACATCACTTCTTCCTC AGCCTGAAGAGTTTCACTTACAATACTATTGGGGAAGATACCGATGTCTTCTTTTCCTTATATGACATGAGGGAAGGCAAGCAGATCAGT GAGCGGTTTCTGGTAAGACTGAACAAGAATGGTGGGCCGAGGAACCCAGAGAAGATAGAACGAATGTGTGCCCTTTTTACAGATCTGAGC AGCAAAGATATGAAGAGAGATTTGTATATCGTTGCCCATGTGATCCGAATAGGCCGGATGCTCCTGAACGACTCAAAGAAAGGTCCTCCT CACCTGCACTACAGGCGACCATATGGCTGTGCGGTCCTAAGCATCTTGGATGTCCTACAGTCACTCACAGAAGTAAAGGAAGAAAAGGAT TTTGTTCTTAAGGTTTACACGTGCAACAACGAGAGTGAGTGGTCCCAGATCCACGAGAACATCATCCGAAAGTCCAGTGCCAAGTACTCT GCCCCCAGCGCCAGCCATGGTCTTATCATTTCTCTGCAGCTTCTTCGTGGAGACATGGAACAGATTCGGAGAGAAAATCCCATGATATTT AATAGGGGATTGGCAATTACAAGAAAATTGGGATTTCCTGATGTCATTATGCCAGGTGATATCCGCAATGACCTGTACCTAACCCTGGAG AAGGGGGATTTCGAGAGAGGAGGAAAGAGTGTACAAAAGAATATTGAAGTGACCATGTATGTGCTTTATGCAGATGGAGAAATCTTGAAG GATTGCATCAGCTTGGGTTCAGGAGAGCCAAATAGGAGTTCCTACCACTCCTTTGTCCTCTACCACAGTAATAGTCCTCGCTGGGGAGAA ATTATCAAATTGCCTATCCCCATTGACCGGTTCCGGGGCTCCCACCTGCGCTTTGAGTTCAGACATTGTTCCACAAAGGACAAAGGGGAA AAGAAACTCTTTGGCTTTGCATTCTCAACCCTGATGCGTGATGATGGCACCACCCTCTCAGATGATATTCACGAGCTTTATGTGTACAAG TGTGATGAGAATAGCACGTTTAATAACCATGCTCTGTACCTGGGCCTGCCCTGCTGCAAAGAGGACTACAATGGCTGCCCTAATATTCCT TCTAGCCTCATCTTCCAGCGCAGCACCAAAGAGTCTTTCTTCATCTCCACTCAGCTCTCCTCTACCAAACTCACCCAGAATGTGGACCTC CTAGCTCTGCTGAAGTGGAAAGCCTTCCCCGACCGGATCATGGATGTACTAGGGCGGCTGCGGCATGTCAGTGGGGAGGAAATTGTTAAG TTTCTGCAGGACATCTTAGATACACTCTTTGTGATTTTGGATGATAATACAGAGAAGTACGGCCTGTTGGTTTTTCAGTCTCTGGTGTTC ATCATCAACCTGCTCCGAGACATCAAGTATTTTCACTTTCGACCTGTGATGGACACGTATATCCAGAAGCACTTTGCTGGAGCTCTGGCA TACAAGGAGCTCATCCGCTGTTTGAAGTGGTATATGGACTGCTCAGCAGAACTGATTCGACAGGACCACATTCAAGAAGCTATGCGGGCC TTGGAGTACCTTTTCAAGTTCATTGTACAGTCACGGATCCTGTACTCACGAGCCACTTGTGGAATGGAAGAGGAACAATTCAGATCCAGT ATCCAAGAACTTTTCCAGTCCATCCGGTTTGTGCTCAGTCTGGACAGCCGAAACTCAGAAACACTCCTTTTTACTCAGGCTGCACTCCTC AATTCTTTCCCAACCATCTTTGATGAGCTTCTGCAAATGTTCACCGTGCAAGAGGTGGCAGAGTTTGTGAGAGGGACACTGGGGAGCATG CCCAGCACTGTGCACATTGGGCAGTCAATGGACGTGGTCAAGCTGCAGTCCATTGCCAGGACAGTGGATAGCCGCCTGTTTTCTTTCTCA GAATCCCGCCGCATCCTGCTTCCTGTGGTTCTCCATCACATTCACCTTCACCTGAGGCAGCAGAAAGAGCTGCTAATTTGCTCAGGGATT CTTGGCAGCATCTTCTCCATCGTCAAGACCAGCTCTCTGGAGGCAGATGTCATGGAGGAAGTAGAGATGATGGTGGAGAGCCTCCTGGAC GTGCTCTTGCAGACTCTGCTCACCATCATGAGCAAATCGCACGCTCAGGAGGCGGTAAGAGGGCAGCGGTGCCCGCAGTGCACAGCCGAG ATCACTGGCGAGTATGTGTCCTGCCTTCTCTCACTGCTCCGCCAGATGTGTGACACCCATTTCCAGCACCTCCTGGACAACTTCCAGAGC AAAGATGAACTCAAGGAATTTCTGCTGAAGATTTTTTGCGTGTTCCGGAACCTGATGAAGATGAGTGTCTTCCCTCGGGACTGGATGGTA ATGAGACTGCTCACAAGCAATATTATAGTCACTACTGTCCAGTACCTGTCCTCTGCACTGCACAAGAATTTCACAGAGACTGACTTTGAC TTTAAGGTGTGGAATTCTTACTTTAGCCTGGCAGTTCTATTCATAAATCAGCCAAGCCTTCAGCTAGAAATTATCACCTCAGCCAAAAGG AAGAAGATTCTAGATAAGTATGGGGACATGCGTGTAATGATGGCCTATGAACTGTTCAGCATGTGGCAGAATTTGGGTGAACATAAGATC CACTTTATTCCGGGAATGATTGGTCCTTTTCTGGGTGTGACACTGGTCCCACAGCCAGAAGTACGGAATATCATGATTCCCATCTTTCAT GACATGATGGACTGGGAGCAGAGAAAAAATGGCAACTTCAAACAGGTGGAGGCCGAGTTGATTGACAAGCTGGACAGCATGGTGTCAGAA GGGAAAGGTGACGAGAGCTACAGGGAGCTCTTCAGCCTACTAACCCAGCTGTTTGGGCCCTACCCCAGCCTGCTGGAGAAGGTTGAACAA GAAACATGGCGCGAGACCGGCATTTCCTTTGTGACCTCAGTCACCCGCCTCATGGAACGTCTTCTTGACTACAGGGACTGCATGAAAGGA GAGGAAACAGAGAATAAGAAGATAGGCTGCACTGTTAACCTGATGAATTTTTACAAATCTGAGATTAACAAGGAAGAAATGTATATCCGC TACATCCATAAGCTTTGTGACATGCACTTGCAGGCCGAAAACTACACAGAGGCCGCATTTACCCTGCTCCTTTACTGTGAGCTGCTGCAG TGGGAGGACCGGCCACTACGGGAATTCCTCCACTACCCATCGCAGACAGAGTGGCAGCGGAAGGAGGGACTGTGCCGGAAGATCATTCAC TACTTCAACAAAGGCAAGAGCTGGGAGTTTGGGATCCCACTGTGCAGGGAGCTGGCGTGTCAGTACGAGAGCCTCTATGATTACCAGAGC CTCAGCTGGATTCGGAAAATGGAGGCCAGCTACTATGACAACATTATGGAGCAGCAACGCCTGGAGCCTGAGTTCTTTCGGGTCGGCTTC TATGGCAGGAAGTTTCCTTTCTTTCTTCGGAACAAAGAATACGTGTGCCGTGGCCATGACTACGAGAGGCTGGAGGCCTTCCAGCAGAGG ATGCTCAGTGAGTTTCCGCAGGCTGTCGCCATGCAGCACCCCAACCATCCTGATGACGCCATCCTACAGTGCGATGCCCAGTACTTGCAG ATCTATGCAGTGACGCCCATTCCAGATTATGTGGATGTTCTGCAGATGGATAGGGTACCAGATCGAGTCAAGAGCTTCTATCGCGTCAAC AATGTGAGGAAGTTCCGGTATGACAGGCCTTTTCACAAAGGCCCCAAGGACAAGGAGAATGAATTCAAGAGCCTGTGGATTGAACGTACC ACACTGACCCTGACCCACAGCTTGCCTGGCATCTCTCGGTGGTTTGAAGTGGAGAGGAGGGAACTGGTGGAGGTGAGCCCTCTGGAGAAT GCCATCCAAGTGGTTGAGAATAAGAACCAGGAGCTACGCTCCCTGATCAGCCAGTATCAACACAAGCAGGTGCATGGCAACATTAACCTG CTAAGCATGTGCCTGAATGGTGTCATTGATGCAGCTGTCAATGGAGGCATTGCACGCTATCAGGAGGCCTTCTTTGATAAAGATTACATC AACAAGCACCCAGGAGATGCTGAGAAGATCACCCAGCTCAAGGAGCTTATGCAGGAGCAGGTTCATGTCCTTGGAGTTGGGCTAGCAGTT CATGAGAAGTTTGTGCACCCAGAAATGCGGCCTCTGCATAAGAAGCTAATTGATCAGTTCCAGATGATGCGGGCCAGTCTCTACCATGAG TTTCCAGGTTTGGATAAGCTAAGTCCTGCATGTTCAGGCACCAGCACCCCACGGGGAAATGTTCTGGCATCCCATAGCCCCATGAGTCCG GAGAGCATCAAGATGACCCACCGGCACAGCCCCATGAACTTGATGGGCACAGGCCGCCATTCATCATCCTCTCTCTCCTCACATGCGTCT AGTGAAGCAGGAAACATGGTGATGCTGGGTGACGGCTCCATGGGTGATGCTCCTGAGGACCTGTACCACCACATGCAGCTCGCGTATCCC AACCCCAGGTACCAAGGCTCAGTCACCAACGTCTCTGTTCTGTCCTCGTCCCAGGCAAGCCCTTCTTCCTCCAGCCTGAGTTCCACTCAC TCAGCACCATCCCAGATGATTACCTCTGCCCCTTCCAGTGCCCGAGGCTCTCCCTCTCTGCCAGATAAGTACCGCCATGCCCGTGAAATG ATGTTGTTGCTGCCCACATACCGGGACCGCCCAAGCAGTGCCATGTATCCAGCAGCCATCCTGGAGAACGGACAGCCGCCGAATTTCCAG CGAGCCCTGTTCCAGCAAGTGGTCGGAGCCTGCAAACCCTGCAGTGATCCCAATCTGTCTGTGGCTGAAAAAGGTCATTACTCCCTACAC TTTGACGCCTTCCACCACCCTCTGGGTGATACCCCCCCAGCCCTCCCTGCCCGGACCCTGCGCAAGTCTCCTCTCCACCCTATCCCAGCC TCCCCCACAAGCCCCCAGTCAGGTCTGGACGGCAGCAACTCTACGCTGTCCGGCAGTGCCAGCAGCGGCGTGTCCTCCTTGAGTGAGAGT AACTTTGGGCACTCCTCGGAGGCCCCACCTCGCACTGACACCATGGACTCCATGCCAAGTCAGGCCTGGAATGCTGACGAAGATCTTGAG CCACCCTACCTCCCTGTCCACTACAGCCTCTCTGAGTCTGCCGTCCTGGACTCCATCAAGGCCCAGCCATGCCGAAGCCACTCAGCCCCA GGGTGCGTCATCCCTCAGGACCCCATGGACCCGCCTGCGCTGCCGCCCAAGCCCTACCACCCCCGCCTGCCGGCCCTGGAGCACGATGAG GGGGTGCTGCTGCGTGAAGAGACTGAGAGGCCTCGAGGCCTGCACCGCAAGGCTCCATTGCCTCCTGGGAGCGCTAAGGAGGAGCAGGCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SMARCC1_ENST00000254480_chr3_47814307_-_DOCK3_ENST00000266037_chr3_50927457_+_9005nt GGCTGGGCGGGGCCGGGAAGCGGCAGTGGCGGCTACGCGCGCGGGGGTGCGCGCGGGAACGACCGGGAAACACCGCGAGGGCCGGGGTGG GCCAGGCTGTGGGGACGACGGGCTGCGACGATGGCCGCAGCGGCGGGCGGCGGCGGGCCGGGGACAGCGGTAGGCGCCACGGGCTCGGGG ATTGCGGCGGCAGCCGCAGGCCTAGCTGTTTATCGACGGAAGGATGGGGGCCCGGCCACCAAGTTTTGGGAGAGCCCGGAGACGGTGTCC CAGCTGGATTCGGTGCGGGTCTGGCTGGGCAAGCACTACAAGAAGTATGTTCATGCGGATGCTCCTACCAATAAAACACTGGCTGGGCTG GTGGTGCAGCTTCTTCAGTTCCAGGAAGATGCCTTTGGGAAGCATGTCACCAACCCGGCCTTCACCAAACTCCCTGGGATCTTTCCTGCA AATTACATTCACTTGAAAAAGGCAATTGTCAGTAATAGGGGGCAGTATGAAACTGTGGTTCCACTTGAAGATTCTATTGTGACTGAGGTT ACAGCAACTCTACAAGAATGGGCAAGTTTGTGGAAACAGTTGTATGTGAAACACAAAGTAGATCTTTTCTACAAACTACGCCATGTGATG AATGAACTTATTGACCTGCGAAGGCAGCTACTGTCTGGTCACCTGACTCAGGATCAGGTGCGGGAGGTTAAGCGGCACATCACCGTGCGC CTGGACTGGGGTAATGAACATTTGGGCCTGGACCTGGTGCCTCGGAAGGACTTTGAAGTAGTGGACTCGGACCAGATTAGTGTCTCAGAT CTCTATAAGATGCATTTATCTAGCCGGCAGAGTGTACAGCAAAGCACATCCCAGGTAGATACAATGCGCCCACGTCATGGGGAAACATGT CGGATGCCAGTGCCACATCACTTCTTCCTCAGCCTGAAGAGTTTCACTTACAATACTATTGGGGAAGATACCGATGTCTTCTTTTCCTTA TATGACATGAGGGAAGGCAAGCAGATCAGTGAGCGGTTTCTGGTAAGACTGAACAAGAATGGTGGGCCGAGGAACCCAGAGAAGATAGAA CGAATGTGTGCCCTTTTTACAGATCTGAGCAGCAAAGATATGAAGAGAGATTTGTATATCGTTGCCCATGTGATCCGAATAGGCCGGATG CTCCTGAACGACTCAAAGAAAGGTCCTCCTCACCTGCACTACAGGCGACCATATGGCTGTGCGGTCCTAAGCATCTTGGATGTCCTACAG TCACTCACAGAAGTAAAGGAAGAAAAGGATTTTGTTCTTAAGGTTTACACGTGCAACAACGAGAGTGAGTGGTCCCAGATCCACGAGAAC ATCATCCGAAAGTCCAGTGCCAAGTACTCTGCCCCCAGCGCCAGCCATGGTCTTATCATTTCTCTGCAGCTTCTTCGTGGAGACATGGAA CAGATTCGGAGAGAAAATCCCATGATATTTAATAGGGGATTGGCAATTACAAGAAAATTGGGATTTCCTGATGTCATTATGCCAGGTGAT ATCCGCAATGACCTGTACCTAACCCTGGAGAAGGGGGATTTCGAGAGAGGAGGAAAGAGTGTACAAAAGAATATTGAAGTGACCATGTAT GTGCTTTATGCAGATGGAGAAATCTTGAAGGATTGCATCAGCTTGGGTTCAGGAGAGCCAAATAGGAGTTCCTACCACTCCTTTGTCCTC TACCACAGTAATAGTCCTCGCTGGGGAGAAATTATCAAATTGCCTATCCCCATTGACCGGTTCCGGGGCTCCCACCTGCGCTTTGAGTTC AGACATTGTTCCACAAAGGACAAAGGGGAAAAGAAACTCTTTGGCTTTGCATTCTCAACCCTGATGCGTGATGATGGCACCACCCTCTCA GATGATATTCACGAGCTTTATGTGTACAAGTGTGATGAGAATAGCACGTTTAATAACCATGCTCTGTACCTGGGCCTGCCCTGCTGCAAA GAGGACTACAATGGCTGCCCTAATATTCCTTCTAGCCTCATCTTCCAGCGCAGCACCAAAGAGTCTTTCTTCATCTCCACTCAGCTCTCC TCTACCAAACTCACCCAGAATGTGGACCTCCTAGCTCTGCTGAAGTGGAAAGCCTTCCCCGACCGGATCATGGATGTACTAGGGCGGCTG CGGCATGTCAGTGGGGAGGAAATTGTTAAGTTTCTGCAGGACATCTTAGATACACTCTTTGTGATTTTGGATGATAATACAGAGAAGTAC GGCCTGTTGGTTTTTCAGTCTCTGGTGTTCATCATCAACCTGCTCCGAGACATCAAGTATTTTCACTTTCGACCTGTGATGGACACGTAT ATCCAGAAGCACTTTGCTGGAGCTCTGGCATACAAGGAGCTCATCCGCTGTTTGAAGTGGTATATGGACTGCTCAGCAGAACTGATTCGA CAGGACCACATTCAAGAAGCTATGCGGGCCTTGGAGTACCTTTTCAAGTTCATTGTACAGTCACGGATCCTGTACTCACGAGCCACTTGT GGAATGGAAGAGGAACAATTCAGATCCAGTATCCAAGAACTTTTCCAGTCCATCCGGTTTGTGCTCAGTCTGGACAGCCGAAACTCAGAA ACACTCCTTTTTACTCAGGCTGCACTCCTCAATTCTTTCCCAACCATCTTTGATGAGCTTCTGCAAATGTTCACCGTGCAAGAGGTGGCA GAGTTTGTGAGAGGGACACTGGGGAGCATGCCCAGCACTGTGCACATTGGGCAGTCAATGGACGTGGTCAAGCTGCAGTCCATTGCCAGG ACAGTGGATAGCCGCCTGTTTTCTTTCTCAGAATCCCGCCGCATCCTGCTTCCTGTGGTTCTCCATCACATTCACCTTCACCTGAGGCAG CAGAAAGAGCTGCTAATTTGCTCAGGGATTCTTGGCAGCATCTTCTCCATCGTCAAGACCAGCTCTCTGGAGGCAGATGTCATGGAGGAA GTAGAGATGATGGTGGAGAGCCTCCTGGACGTGCTCTTGCAGACTCTGCTCACCATCATGAGCAAATCGCACGCTCAGGAGGCGGTAAGA GGGCAGCGGTGCCCGCAGTGCACAGCCGAGATCACTGGCGAGTATGTGTCCTGCCTTCTCTCACTGCTCCGCCAGATGTGTGACACCCAT TTCCAGCACCTCCTGGACAACTTCCAGAGCAAAGATGAACTCAAGGAATTTCTGCTGAAGATTTTTTGCGTGTTCCGGAACCTGATGAAG ATGAGTGTCTTCCCTCGGGACTGGATGGTAATGAGACTGCTCACAAGCAATATTATAGTCACTACTGTCCAGTACCTGTCCTCTGCACTG CACAAGAATTTCACAGAGACTGACTTTGACTTTAAGGTGTGGAATTCTTACTTTAGCCTGGCAGTTCTATTCATAAATCAGCCAAGCCTT CAGCTAGAAATTATCACCTCAGCCAAAAGGAAGAAGATTCTAGATAAGTATGGGGACATGCGTGTAATGATGGCCTATGAACTGTTCAGC ATGTGGCAGAATTTGGGTGAACATAAGATCCACTTTATTCCGGGAATGATTGGTCCTTTTCTGGGTGTGACACTGGTCCCACAGCCAGAA GTACGGAATATCATGATTCCCATCTTTCATGACATGATGGACTGGGAGCAGAGAAAAAATGGCAACTTCAAACAGGTGGAGGCCGAGTTG ATTGACAAGCTGGACAGCATGGTGTCAGAAGGGAAAGGTGACGAGAGCTACAGGGAGCTCTTCAGCCTACTAACCCAGCTGTTTGGGCCC TACCCCAGCCTGCTGGAGAAGGTTGAACAAGAAACATGGCGCGAGACCGGCATTTCCTTTGTGACCTCAGTCACCCGCCTCATGGAACGT CTTCTTGACTACAGGGACTGCATGAAAGGAGAGGAAACAGAGAATAAGAAGATAGGCTGCACTGTTAACCTGATGAATTTTTACAAATCT GAGATTAACAAGGAAGAAATGTATATCCGCTACATCCATAAGCTTTGTGACATGCACTTGCAGGCCGAAAACTACACAGAGGCCGCATTT ACCCTGCTCCTTTACTGTGAGCTGCTGCAGTGGGAGGACCGGCCACTACGGGAATTCCTCCACTACCCATCGCAGACAGAGTGGCAGCGG AAGGAGGGACTGTGCCGGAAGATCATTCACTACTTCAACAAAGGCAAGAGCTGGGAGTTTGGGATCCCACTGTGCAGGGAGCTGGCGTGT CAGTACGAGAGCCTCTATGATTACCAGAGCCTCAGCTGGATTCGGAAAATGGAGGCCAGCTACTATGACAACATTATGGAGCAGCAACGC CTGGAGCCTGAGTTCTTTCGGGTCGGCTTCTATGGCAGGAAGTTTCCTTTCTTTCTTCGGAACAAAGAATACGTGTGCCGTGGCCATGAC TACGAGAGGCTGGAGGCCTTCCAGCAGAGGATGCTCAGTGAGTTTCCGCAGGCTGTCGCCATGCAGCACCCCAACCATCCTGATGACGCC ATCCTACAGTGCGATGCCCAGTACTTGCAGATCTATGCAGTGACGCCCATTCCAGATTATGTGGATGTTCTGCAGATGGATAGGGTACCA GATCGAGTCAAGAGCTTCTATCGCGTCAACAATGTGAGGAAGTTCCGGTATGACAGGCCTTTTCACAAAGGCCCCAAGGACAAGGAGAAT GAATTCAAGAGCCTGTGGATTGAACGTACCACACTGACCCTGACCCACAGCTTGCCTGGCATCTCTCGGTGGTTTGAAGTGGAGAGGAGG GAACTGGTGGAGGTGAGCCCTCTGGAGAATGCCATCCAAGTGGTTGAGAATAAGAACCAGGAGCTACGCTCCCTGATCAGCCAGTATCAA CACAAGCAGGTGCATGGCAACATTAACCTGCTAAGCATGTGCCTGAATGGTGTCATTGATGCAGCTGTCAATGGAGGCATTGCACGCTAT CAGGAGGCCTTCTTTGATAAAGATTACATCAACAAGCACCCAGGAGATGCTGAGAAGATCACCCAGCTCAAGGAGCTTATGCAGGAGCAG GTTCATGTCCTTGGAGTTGGGCTAGCAGTTCATGAGAAGTTTGTGCACCCAGAAATGCGGCCTCTGCATAAGAAGCTAATTGATCAGTTC CAGATGATGCGGGCCAGTCTCTACCATGAGTTTCCAGGTTTGGATAAGCTAAGTCCTGCATGTTCAGGCACCAGCACCCCACGGGGAAAT GTTCTGGCATCCCATAGCCCCATGAGTCCGGAGAGCATCAAGATGACCCACCGGCACAGCCCCATGAACTTGATGGGCACAGGCCGCCAT TCATCATCCTCTCTCTCCTCACATGCGTCTAGTGAAGCAGGAAACATGGTGATGCTGGGTGACGGCTCCATGGGTGATGCTCCTGAGGAC CTGTACCACCACATGCAGCTCGCGTATCCCAACCCCAGGTACCAAGGCTCAGTCACCAACGTCTCTGTTCTGTCCTCGTCCCAGGCAAGC CCTTCTTCCTCCAGCCTGAGTTCCACTCACTCAGCACCATCCCAGATGATTACCTCTGCCCCTTCCAGTGCCCGAGGCTCTCCCTCTCTG CCAGATAAGTACCGCCATGCCCGTGAAATGATGTTGTTGCTGCCCACATACCGGGACCGCCCAAGCAGTGCCATGTATCCAGCAGCCATC CTGGAGAACGGACAGCCGCCGAATTTCCAGCGAGCCCTGTTCCAGCAAGTGGTCGGAGCCTGCAAACCCTGCAGTGATCCCAATCTGTCT GTGGCTGAAAAAGGTCATTACTCCCTACACTTTGACGCCTTCCACCACCCTCTGGGTGATACCCCCCCAGCCCTCCCTGCCCGGACCCTG CGCAAGTCTCCTCTCCACCCTATCCCAGCCTCCCCCACAAGCCCCCAGTCAGGTCTGGACGGCAGCAACTCTACGCTGTCCGGCAGTGCC AGCAGCGGCGTGTCCTCCTTGAGTGAGAGTAACTTTGGGCACTCCTCGGAGGCCCCACCTCGCACTGACACCATGGACTCCATGCCAAGT CAGGCCTGGAATGCTGACGAAGATCTTGAGCCACCCTACCTCCCTGTCCACTACAGCCTCTCTGAGTCTGCCGTCCTGGACTCCATCAAG GCCCAGCCATGCCGAAGCCACTCAGCCCCAGGGTGCGTCATCCCTCAGGACCCCATGGACCCGCCTGCGCTGCCGCCCAAGCCCTACCAC CCCCGCCTGCCGGCCCTGGAGCACGATGAGGGGGTGCTGCTGCGTGAAGAGACTGAGAGGCCTCGAGGCCTGCACCGCAAGGCTCCATTG CCTCCTGGGAGCGCTAAGGAGGAGCAGGCCCGCATGGCCTGGGAGCACGGCCGAGGGGAGCAGTGAGGGGCAACGAGGCGGCTGGGATGC CGCCCTCAGTAAGCAGCTTGCCAATCACTCCAGGTCTGAAAAGCAAGTCCCCCAGCCCCACCCCAGGGAGCCAGAGAGGCTTGCACTCAG GAGAGAACCACCCCCAAGTCTCCGTTCTACTGCCGTGAACTCATGTGTTGCCATGTACAGAGGCCACAGCAGCATGAAGGGTTGTGGCTT CCCTTTTTATTTTTTTACATTTCCATTTCTATGGGTTTTCCTTTCTTTCCTTTATGCAGTAGATGCTTTCTTCCTCCTGCAGTTCTGGAC CATGTGGAGCTACATGGAGAAATTGCACAGACAGAATCACTTTGCCACACTGCAGGGCCCAGGAGTGGGAGCCCAGGCCCTCCCTCCAGG GTAGAGATGCACCGAATGGAAATTGCACTAAGGACCTCTTCCTTTGCTGTATGGACAGAAGAGTTCATGGTTGCATTCAGGGATTGCAAG GACCATATAGACATGTCACAGGTGGAAAAAGGGCCACAAGCCGTTTTGCACAAATGCCTGCCCACCTGCCCCTCTTCCATCCAGGAGTGT GCTACTGAGGGGCTGGCTGGACCAACCTGCTGGCTCAGGCATGTGACTGGCCTAACTGCATGCCCAGGGCACTGCCAGGGTTCAATGGGC CAGCCGTCTCCTACTCCACCTTGGATTTTTCTCTCCATCACATCATTTCTGACCATTTGCTCCCTTCCATTCTTGAAACACCTCATGCCC CACAGGAGCCCCAGTGGTGACTGGATCTGCAAGGGTTATCTCCCGCCCTCTGGGGTTTGAGTGGAGGTATGGAGCCAGAGAGGCTATCCT AGCTACCTTCCTCCTAGGGGGAGCTGGTCCCCTTCCTATGTGGTAGAGAGACTGGTGTAAGAGTGTGGGGTGTGGCAGGCGCCGGAAATC CTCAAAGCTTTCAGAAGCATCCAGAATGCCTACCATCAGCTCCTGAATCAGGGATTTTCAGCACTACCTCTGAGCCATGGGGTTGGCTGC CCAGCCAGGCTTCCAGGCCCTGAGGACATGTGGTCAGGTTCAGCAGGCTCCTGGGTAAAGAGGGTGGGAGGGGGCTTCTCCTTTTGGAAG CAGATAGCCATGCAGGTAGAATTGTCATCTCCCAAGTGGCCACATACAGCAACCCACTCCAGGCCATGGGGACCACCACTCAGGGTTCGG GGCTGGCAGGAGGGTAGTTTCTCCAGTCTCCCCAGTCTGTTGGTGTCTTTATAGGAAACTATAAAGCAGAGCAGTGGTGTCTTTAGAGGA AACTCATTCAAGTCAGGGCACTGATTTTCCTCTCAGTTTATTATTTGGGGGGATAGGGTCAGGTGGGTATAGTAGTACTTTACCAGGGTG CTTTTAAGTTACTTTAAAAAAAGCCTACAAAATATTTTTTTTCTTTTATTTGCTCGAGTTCACATTAATGATGGTCACAAGGCTGCCTTG TTGGGCAGGCGTATTGCCCCCAGTTCCTCTTCTGCTGGCCTGTATGACCTCCACAGCCAGGCCCTGGGCCCAAGCCCCTTGTCCCTTCTC CACTGCCCCTCTTTCCAGACAGTAAAGGCCATGGTCAGTGTGTTTTTCTCTTGTAAACAAACCCCAGCTTGTTTAACAGAAATGCTAATA ACCTACTGGGAAAGATGGAGGTCTAAATTACCTCCAGGGTTTTTCTGGGGGTTTATCACCAGTGTGGGTCCCTTCTGATACCACCAGGTT CACTCCAGGCAGAGTGGGGCGGAAGGCTGCTGAGGATATGGGTCAGTTACAGCAGCCCTCACCTCAAAGGGCTGGCCTGCTTCTCAGCCT ACATTCATTTGCAAGCTTCAATCTCTGGACCATCTGGTGTTCACAGGTGTTAGAGGGTTAGGGGTTAGGGGCTAGTTTTGGATTTGATTC ATAGGTAGGAGGGCTTAGATTTTAAGGCACTTCTGAAAGTCAATCCCTGGACAAGGCAGTCATCACATAAGAACAGCTACCTTCTCCACT TGGTGGCACAAGAGGTAGGGAGGGGAGTATGGGTTCATTTGGCTTCGCATTATGCAAGGTGAAACCGTTTGTTTTCCCTCTCCATTTTCC CTAACTAAATGAAAAGGACACATTCTGAAATCCCTTTTGTTGGAGAATAAGTCAGTCTGAGGGGAAATGGGAGGCCAGAGATGAGAACCC TTTGAAAAGATTGTAAAATACTGATTTTCATTCTTTCAAGCTTATTTGTAAATACCTATTTGAATGCTGTGTATTTGTACAGGAATTTGA GCAAAAAATGTATAGAGTGTGATGTCCAATTGGTATTCAGCACTATAAATGTGTTTTTAACCTCCCGCATTCTGTGCTTATTTAAAACAA GGAAACTTCTAACCATTTCTTTTGTGTATTCATGTTTAAAGAAAAAAAGTGATTTAAAAATGATCTTACCTGTACCAGAAAAGCAAAGTT AAAGGAAACAAAATTTGTACCATTGTCCCAAGAGGTATTTTACTGTATATATTGTGGTAGCATGTTCAAAATCCAACAAGTAATGTGAAT TTTAGATGTAAATATCTGCCACTTGATTTTTTTTCCCCCTTTCCCCACTTCCTTGACTGCTGTGATGTGAATTAAAGATAAATACGTGAT |
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FusionGenePPI for SMARCC1_DOCK3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SMARCC1 | RELB, NR3C1, SMARCD1, SMARCB1, SMARCA4, SMARCA2, SIN3A, KLF1, GATA1, SP1, TP53, BRCA1, STAT2, CCNE1, HSP90B1, NCOR1, SMARCE1, CEBPB, CDK8, ING1, AR, ING2, TAF10, NR4A1, ARID1A, SMARCC2, PBRM1, ADD1, MCPH1, BCL7C, BRD7, ARID1B, AKT1, PRMT5, MYC, SMARCC1, HNRNPC, CHD4, SRRM2, TAF6, NR0B2, NONO, SMAD2, SMAD3, CARM1, EMD, DPF2, TRIM28, RUNX1, CHD7, ARID2, STK11, WHSC1L1, SMARCAD1, SOX2, ELAVL1, SIRT7, DPF3, PHF10, DPF1, ACTL6A, CUL3, CAND1, BAZ1B, SMARCD2, TOP2B, HDAC1, SMARCA5, RBBP5, KDM1A, SMARCA1, NOTCH1, EPAS1, VCP, HDAC6, ITCH, NEDD4, WWOX, AURKB, OTX1, PLSCR1, ADAMTSL4, MOV10, NXF1, MSL1, EED, RNF2, BMI1, SS18, NTRK1, MESDC2, MRE11A, SAMD9, BCL7A, CPSF6, DCTN2, FUBP1, FUBP3, KHSRP, MDC1, METTL13, NCAPH2, SF3A1, TMOD3, YLPM1, SMARCD3, SS18L1, TBL1XR1, NCOA1, KMT2A, EWSR1, HIST1H3E, RAB5C, NR2C2, FOS, JUN, NFATC1, NFATC2, C1orf131, SFPQ, CHEK1, TRIM25 | DOCK3 | CALM1, KHDRBS1, ELMO1, SRPK2, ELMO3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SMARCC1_DOCK3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SMARCC1_DOCK3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SMARCC1 | C0001418 | Adenocarcinoma | 1 | CTD_human |
| Hgene | SMARCC1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Hgene | SMARCC1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
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