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Fusion gene ID: 34500 |
FusionGeneSummary for SLC43A2_SMG6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC43A2_SMG6 | Fusion gene ID: 34500 | Hgene | Tgene | Gene symbol | SLC43A2 | SMG6 | Gene ID | 124935 | 23293 |
| Gene name | solute carrier family 43 member 2 | SMG6, nonsense mediated mRNA decay factor | |
| Synonyms | LAT4 | C17orf31|EST1A|SMG-6|hSMG5/7a | |
| Cytomap | 17p13.3 | 17p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | large neutral amino acids transporter small subunit 4L-type amino acid transporter 4solute carrier family 43 (amino acid system L transporter), member 2 | telomerase-binding protein EST1AEST1 telomerase component homolog Aever shorter telomeres 1Asmg-6 homolog, nonsense mediated mRNA decay factortelomerase subunit EST1A | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8N370 | Q86US8 | |
| Ensembl transtripts involved in fusion gene | ENST00000301335, ENST00000571650, ENST00000382147, ENST00000412517, ENST00000574274, | ENST00000544865, ENST00000263073, ENST00000354901, ENST00000536871, ENST00000573166, | |
| Fusion gene scores | * DoF score | 5 X 3 X 4=60 | 8 X 6 X 5=240 |
| # samples | 5 | 8 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SLC43A2 [Title/Abstract] AND SMG6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | SMG6 | GO:1904354 | negative regulation of telomere capping | 12676087 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A06Z-01A | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000301335 | ENST00000544865 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| In-frame | ENST00000301335 | ENST00000263073 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000301335 | ENST00000354901 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000301335 | ENST00000536871 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000301335 | ENST00000573166 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| Frame-shift | ENST00000571650 | ENST00000544865 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| Frame-shift | ENST00000571650 | ENST00000263073 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000571650 | ENST00000354901 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000571650 | ENST00000536871 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000571650 | ENST00000573166 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| In-frame | ENST00000382147 | ENST00000544865 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| In-frame | ENST00000382147 | ENST00000263073 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000382147 | ENST00000354901 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000382147 | ENST00000536871 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| 5CDS-intron | ENST00000382147 | ENST00000573166 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-3CDS | ENST00000412517 | ENST00000544865 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-3CDS | ENST00000412517 | ENST00000263073 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-intron | ENST00000412517 | ENST00000354901 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-intron | ENST00000412517 | ENST00000536871 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-intron | ENST00000412517 | ENST00000573166 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-3CDS | ENST00000574274 | ENST00000544865 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-3CDS | ENST00000574274 | ENST00000263073 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-intron | ENST00000574274 | ENST00000354901 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-intron | ENST00000574274 | ENST00000536871 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
| intron-intron | ENST00000574274 | ENST00000573166 | SLC43A2 | chr17 | 1516489 | - | SMG6 | chr17 | 2187029 | - |
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FusionProtFeatures for SLC43A2_SMG6 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC43A2 | SMG6 |
| Component of the telomerase ribonucleoprotein (RNP)complex that is essential for the replication of chromosometermini. May have a general role in telomere regulation. Promotesin vitro the ability of TERT to elongate telomeres. Overexpressioninduces telomere uncapping, chromosomal end-to-end fusions(telomeric DNA persists at the fusion points) and did not perturbTRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNAtemplate component (TER). Plays a role in nonsense-mediated mRNA decay. Is thoughtto provide a link to the mRNA degradation machinery as it hasendonuclease activity required to initiate NMD, and to serve as anadapter for UPF1 to protein phosphatase 2A (PP2A), therebytriggering UPF1 dephosphorylation. Degrades single-stranded RNA(ssRNA), but not ssDNA or dsRNA. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 120_140 | 167 | 570 | Transmembrane | Helical |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 143_163 | 167 | 570 | Transmembrane | Helical |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 20_40 | 167 | 570 | Transmembrane | Helical |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 90_110 | 167 | 570 | Transmembrane | Helical |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 120_140 | 167 | 574 | Transmembrane | Helical |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 143_163 | 167 | 574 | Transmembrane | Helical |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 20_40 | 167 | 574 | Transmembrane | Helical |
| Hgene | SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 90_110 | 167 | 574 | Transmembrane | Helical |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000263073 | - | 5 | 19 | 1197_1239 | 779 | 1420 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000354901 | - | 0 | 12 | 1197_1239 | -99 | 512 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000354901 | - | 0 | 12 | 163_193 | -99 | 512 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000354901 | - | 0 | 12 | 567_625 | -99 | 512 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000536871 | - | 0 | 11 | 1197_1239 | -81 | 512 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000536871 | - | 0 | 11 | 163_193 | -81 | 512 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000536871 | - | 0 | 11 | 567_625 | -81 | 512 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000544865 | - | 5 | 19 | 1197_1239 | 748 | 1389 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000263073 | - | 5 | 19 | 1246_1397 | 779 | 1420 | Domain | Note=PINc |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000354901 | - | 0 | 12 | 1246_1397 | -99 | 512 | Domain | Note=PINc |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000536871 | - | 0 | 11 | 1246_1397 | -81 | 512 | Domain | Note=PINc |
| Tgene | >SMG6 | chr17:1516489 | chr17:2187029 | ENST00000544865 | - | 5 | 19 | 1246_1397 | 748 | 1389 | Domain | Note=PINc |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 409_413 | 167 | 570 | Compositional bias | Note=Poly-Lys |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 409_413 | 167 | 574 | Compositional bias | Note=Poly-Lys |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 177_197 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 203_223 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 323_345 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 365_385 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 435_455 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 462_482 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 490_510 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000301335 | - | 5 | 14 | 516_536 | 167 | 570 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 177_197 | 167 | 574 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 203_223 | 167 | 574 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 323_345 | 167 | 574 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 365_385 | 167 | 574 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 435_455 | 167 | 574 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 462_482 | 167 | 574 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 490_510 | 167 | 574 | Transmembrane | Helical |
| Hgene | >SLC43A2 | chr17:1516489 | chr17:2187029 | ENST00000571650 | - | 5 | 15 | 516_536 | 167 | 574 | Transmembrane | Helical |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000263073 | - | 5 | 19 | 163_193 | 779 | 1420 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000263073 | - | 5 | 19 | 567_625 | 779 | 1420 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000544865 | - | 5 | 19 | 163_193 | 748 | 1389 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000544865 | - | 5 | 19 | 567_625 | 748 | 1389 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for SLC43A2_SMG6 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SLC43A2_ENST00000301335_chr17_1516489_-_SMG6_ENST00000544865_chr17_2187029_-_808aa MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNL AFTVGSFLLSAITLPLGIVMDKYGPRKLRLLGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTRRKLDAVYYYMRS LAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKSTFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGS LSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAA ALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLA DFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG >In-frame_SLC43A2_ENST00000301335_chr17_1516489_-_SMG6_ENST00000263073_chr17_2187029_-_808aa MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNL AFTVGSFLLSAITLPLGIVMDKYGPRKLRLLGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTRRKLDAVYYYMRS LAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKSTFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGS LSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAA ALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLA DFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG >In-frame_SLC43A2_ENST00000382147_chr17_1516489_-_SMG6_ENST00000544865_chr17_2187029_-_808aa MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNL AFTVGSFLLSAITLPLGIVMDKYGPRKLRLLGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTRRKLDAVYYYMRS LAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKSTFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGS LSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAA ALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLA DFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG >In-frame_SLC43A2_ENST00000382147_chr17_1516489_-_SMG6_ENST00000263073_chr17_2187029_-_808aa MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNL AFTVGSFLLSAITLPLGIVMDKYGPRKLRLLGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTRRKLDAVYYYMRS LAASNPILTAKESLMSLFEETKRKAEQMEKKQHEEFDLSPDQWRKGKKSTFRHVGDDTTRLEIWIHPSHPRSSQGTESGKDSEQENGLGS LSPSDLNKRFILSFLHAHGKLFTRIGMETFPAVAEKVLKEFQVLLQHSPSPIGSTRMLQLMTINMFAVHNSQLKDCFSEECRSVIQEQAA ALGLAMFSLLVRRCTCLLKESAKAQLSSPEDQDDQDDIKVSSFVPDLKELLPSVKVWSDWMLGYPDTWNPPPTSLDLPSHVAVDVWSTLA DFCNILTAVNQSEVPLYKDPDDDLTLLILEEDRLLSGFVPLLAAPQDPCYVEKTSDKVIAADCKRVTVLKYFLEALCGQEEPLLAFKGGK YVSVAPVPDTMGKEMGSQEGTRLEDEEEDVVIEDFEEDSEAEGSGGEDDIRELRAKKLALARKIAEQQRRQEKIQAVLEDHSQMRQMELE IRPLFLVPDTNGFIDHLASLARLLESRKYILVVPLIVINELDGLAKGQETDHRAGGYARVVQEKARKSIEFLEQRFESRDSCLRALTSRG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SLC43A2_ENST00000301335_chr17_1516489_-_SMG6_ENST00000544865_chr17_2187029_-_2424nt ATGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTC CTGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACA GTGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTG GCCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTG CTGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCC CTGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGT TTAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAG AAGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGC CTGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGC CTGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTC CCTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTT ATGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCA GCTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAG GACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGG ATGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCT GATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAA GAGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCA GCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAG TATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTG GTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTG GCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAA ATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATC CTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTG GTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGC AATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCAC TACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGAC >In-frame_SLC43A2_ENST00000301335_chr17_1516489_-_SMG6_ENST00000263073_chr17_2187029_-_2424nt ATGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTC CTGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACA GTGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTG GCCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTG CTGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCC CTGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGT TTAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAG AAGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGC CTGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGC CTGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTC CCTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTT ATGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCA GCTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAG GACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGG ATGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCT GATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAA GAGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCA GCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAG TATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTG GTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTG GCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAA ATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATC CTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTG GTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGC AATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCAC TACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGAC >In-frame_SLC43A2_ENST00000382147_chr17_1516489_-_SMG6_ENST00000544865_chr17_2187029_-_2424nt ATGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTC CTGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACA GTGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTG GCCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTG CTGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCC CTGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGT TTAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAG AAGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGC CTGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGC CTGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTC CCTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTT ATGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCA GCTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAG GACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGG ATGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCT GATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAA GAGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCA GCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAG TATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTG GTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTG GCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAA ATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATC CTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTG GTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGC AATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCAC TACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGAC >In-frame_SLC43A2_ENST00000382147_chr17_1516489_-_SMG6_ENST00000263073_chr17_2187029_-_2424nt ATGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTC CTGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACA GTGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTG GCCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTG CTGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCC CTGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGT TTAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAG AAGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGC CTGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGC CTGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTC CCTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTT ATGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCA GCTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAG GACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGG ATGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCT GATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAA GAGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCA GCTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAG TATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTG GTGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTG GCCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAA ATCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATC CTGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTG GTACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGC AATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCAC TACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SLC43A2_ENST00000301335_chr17_1516489_-_SMG6_ENST00000544865_chr17_2187029_-_4166nt AGAAAAGGCGCCGGGCGGGCCCGACACACGCCGGAGGAGCCGGGTGGTGCAGAGCCGGAGCCGGAGCCGGAGCCGCGCCGCGCCGCACCA TGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTCC TGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACAG TGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTGG CCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTGC TGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCCC TGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGTT TAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAGA AGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGCC TGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGCC TGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTCC CTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTTA TGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCAG CTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAGG ACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGGA TGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCTG ATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAAG AGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCAG CTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGT ATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGG TGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGG CCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAA TCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCC TGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGG TACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCA ATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACT ACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACC GGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCC ACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCA ATCCACCCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATC GGGCGGAAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGG CCGCCCATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCA GTGGAGACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTT CAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGG CTTCTAGACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTC CTCTTCCTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGG TCTCAGGCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTC CTGACTCCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGAT CCTTTTCACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCAT GGCAGGAACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCT GAGGCATTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCC TTTCCTTGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACT TAGGGGAAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAG CCTGCCTGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGC CAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTC CCCAGCTGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAAT >In-frame_SLC43A2_ENST00000301335_chr17_1516489_-_SMG6_ENST00000263073_chr17_2187029_-_4162nt AGAAAAGGCGCCGGGCGGGCCCGACACACGCCGGAGGAGCCGGGTGGTGCAGAGCCGGAGCCGGAGCCGGAGCCGCGCCGCGCCGCACCA TGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTCC TGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACAG TGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTGG CCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTGC TGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCCC TGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGTT TAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAGA AGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGCC TGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGCC TGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTCC CTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTTA TGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCAG CTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAGG ACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGGA TGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCTG ATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAAG AGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCAG CTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGT ATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGG TGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGG CCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAA TCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCC TGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGG TACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCA ATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACT ACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACC GGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCC ACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCA ATCCACCCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATC GGGCGGAAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGG CCGCCCATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCA GTGGAGACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTT CAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGG CTTCTAGACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTC CTCTTCCTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGG TCTCAGGCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTC CTGACTCCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGAT CCTTTTCACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCAT GGCAGGAACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCT GAGGCATTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCC TTTCCTTGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACT TAGGGGAAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAG CCTGCCTGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGC CAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTC CCCAGCTGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAAT >In-frame_SLC43A2_ENST00000382147_chr17_1516489_-_SMG6_ENST00000544865_chr17_2187029_-_4166nt AGAAAAGGCGCCGGGCGGGCCCGACACACGCCGGAGGAGCCGGGTGGTGCAGAGCCGGAGCCGGAGCCGGAGCCGCGCCGCGCCGCACCA TGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTCC TGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACAG TGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTGG CCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTGC TGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCCC TGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGTT TAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAGA AGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGCC TGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGCC TGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTCC CTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTTA TGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCAG CTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAGG ACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGGA TGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCTG ATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAAG AGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCAG CTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGT ATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGG TGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGG CCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAA TCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCC TGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGG TACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCA ATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACT ACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACC GGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCC ACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCA ATCCACCCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATC GGGCGGAAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGG CCGCCCATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCA GTGGAGACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTT CAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGG CTTCTAGACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTC CTCTTCCTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGG TCTCAGGCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTC CTGACTCCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGAT CCTTTTCACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCAT GGCAGGAACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCT GAGGCATTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCC TTTCCTTGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACT TAGGGGAAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAG CCTGCCTGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGC CAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTC CCCAGCTGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAAT >In-frame_SLC43A2_ENST00000382147_chr17_1516489_-_SMG6_ENST00000263073_chr17_2187029_-_4162nt AGAAAAGGCGCCGGGCGGGCCCGACACACGCCGGAGGAGCCGGGTGGTGCAGAGCCGGAGCCGGAGCCGGAGCCGCGCCGCGCCGCACCA TGGCGCCCACCCTGGCCACTGCCCATCGGCGCCGCTGGTGGATGGCCTGCACGGCCGTGCTGGAGAACCTCCTCTTCTCGGCAGTCCTCC TGGGCTGGGGCTCGCTGCTCATCATGCTCAAGTCAGAGGGCTTTTACTCCTACCTGTGTACCGAGCCAGAGAATGTCACCAATGGCACAG TGGGCGGCACAGCAGAGCCGGGGCACGAGGAGGTGAGCTGGATGAACGGCTGGCTCAGCTGCCAGGCCCAGGACGAGATGCTAAATTTGG CCTTCACTGTGGGCTCCTTTCTGCTCAGTGCCATCACCCTGCCCCTGGGTATCGTCATGGACAAGTATGGCCCGAGGAAGCTCAGGCTGC TGGGCAGCGCCTGCTTCGCGGTTTCCTGCTTGCTGATTGCGTACGGAGCAAGTAAACCAAACGCTCTCTCCGTGCTCATCTTCATCGCCC TGGCTCTGAATGGCTTTGGTGGGATGTGTATGACCTTCACCTCATTAACAAGGAGGAAGCTTGACGCTGTCTATTACTATATGCGCAGTT TAGCTGCCAGCAACCCTATCCTGACTGCCAAGGAGAGTCTCATGAGCTTGTTTGAAGAGACCAAGCGGAAGGCAGAACAGATGGAAAAGA AGCAACATGAGGAATTTGACCTGAGCCCTGACCAGTGGCGGAAAGGAAAGAAGTCTACTTTCCGGCATGTTGGAGATGACACCACTCGCC TGGAGATCTGGATTCATCCATCCCATCCACGGTCTTCCCAGGGCACTGAGTCTGGGAAGGATTCTGAGCAAGAGAATGGGCTGGGCAGCC TGAGTCCCAGTGATCTGAACAAAAGGTTCATCCTCAGTTTTCTCCATGCCCATGGGAAGCTGTTTACCCGGATTGGGATGGAGACATTCC CTGCAGTGGCTGAGAAGGTCCTCAAGGAGTTCCAGGTGTTACTGCAGCACAGCCCCTCTCCCATTGGAAGTACCCGCATGCTGCAGCTTA TGACCATCAATATGTTTGCAGTACACAACTCCCAGCTGAAAGACTGCTTCTCGGAGGAGTGCCGCTCTGTGATCCAGGAACAAGCCGCAG CTCTGGGCTTGGCCATGTTTTCTCTACTGGTCCGCCGCTGCACCTGCTTACTTAAGGAGTCCGCCAAAGCTCAGCTGTCCTCTCCTGAGG ACCAGGATGACCAAGACGACATCAAGGTGTCTTCCTTTGTCCCGGACCTGAAGGAGCTGCTCCCCAGTGTCAAAGTCTGGTCAGATTGGA TGCTCGGCTACCCGGACACCTGGAATCCTCCTCCCACATCCCTGGATCTGCCCTCGCATGTTGCTGTGGATGTATGGTCGACGCTGGCTG ATTTCTGTAACATACTGACTGCAGTGAATCAGTCTGAGGTGCCACTGTACAAGGACCCGGATGATGACCTCACCCTTCTTATCCTGGAAG AGGATCGGCTTCTCTCGGGCTTTGTCCCCTTGCTGGCTGCCCCTCAGGACCCCTGCTACGTGGAGAAAACCTCGGATAAGGTTATTGCAG CTGACTGCAAAAGGGTCACAGTGCTGAAGTATTTTCTGGAAGCCCTTTGTGGACAAGAAGAGCCTCTGCTGGCATTCAAGGGTGGAAAGT ATGTGTCAGTGGCACCCGTCCCAGACACCATGGGAAAGGAAATGGGAAGCCAAGAGGGAACACGACTGGAAGATGAGGAGGAGGATGTGG TGATTGAAGACTTTGAGGAAGATTCAGAGGCTGAAGGCAGCGGAGGCGAGGATGACATCAGGGAGCTTCGGGCCAAGAAGCTGGCTCTGG CCAGGAAGATAGCTGAGCAGCAGCGTCGCCAGGAAAAGATCCAGGCTGTCCTGGAGGACCACAGTCAGATGAGGCAGATGGAGCTCGAAA TCAGACCTTTGTTCCTCGTACCAGACACCAACGGCTTCATTGACCACCTGGCCAGTCTGGCGCGGCTGCTGGAGAGCAGGAAGTACATCC TGGTGGTGCCCCTCATCGTGATCAATGAGCTGGACGGCCTGGCCAAGGGGCAGGAGACAGACCACCGGGCTGGGGGCTACGCCCGTGTGG TACAAGAGAAGGCCCGCAAGTCCATCGAGTTCCTCGAGCAGCGATTCGAGAGTCGGGACTCTTGCCTGCGAGCCCTGACCAGCCGTGGCA ATGAACTCGAATCCATCGCCTTCCGCAGTGAGGACATCACTGGCCAGCTGGGTAACAACGATGATCTCATCCTGTCCTGCTGCCTCCACT ACTGCAAAGACAAGGCTAAGGACTTCATGCCCGCCAGCAAAGAGGAGCCAATCCGGCTACTGCGGGAGGTGGTGCTGTTGACGGATGACC GGAACCTGCGTGTGAAGGCGCTCACAAGGAATGTTCCTGTACGGGACATCCCAGCCTTCCTCACGTGGGCCCAGGTGGGCTGAGGGAGCC ACACTGGGGCCCCCCCCCCGTGGAACCGTTCCTGAAAGGCCACCAGGCGCCCAGTGTAGCACGGAAGATGCCCACGTGCCTGAGCCACCA ATCCACCCAGACAATAAACCATCCTCTTCCAACCCACGCCACGGCCATGCTGTGGGGGACCTGCTCCTCACAGAGCCCCTCCCAAGGATC GGGCGGAAGCTGCTGGGACCCTCCTGGGCTGCCAGGATTTAGCAGGGAGGTGGCTGGCTACAGCAACAGCAGCTGGGCAAGCCAGATAGG CCGCCCATGCTCTCAGCCTTTCTCCCTCCCCCGTCTCATTCCAAGGCTGAGGGAGGGCCTTCTCGCCTGGGGACGCAGCCACTTTCTCCA GTGGAGACAGGGCAGGGGTTCTGAGTTTCCGTCAGATGCAGTGAAATCACAGTTCCCTTTCATCTTCAGAACCTCTGTCGTGAATGTGTT CAAGAGGCTTTGGTTAAGTCAGGAAGAAGTGCCCAGGGTGTGTGTCCCCAGTCTCCCTGAGGCCTGGACTCGCCCATGAACCCAAGTCGG CTTCTAGACAGCATGTCCCTAACAGCAGCCCTGGGCCCCCACCTCTTCTACCATCCACCCCAGACTTACCACACACCCTTCCTGCTGCTC CTCTTCCTGCCCTTATCAACCTGGGTCCCTCACACTTCGCCAGTTGCGTCCCCGTGGACAGTCATGAGTCTAGAGGAAAGGGGCATCTGG TCTCAGGCCCGTGCTCTCGGGTGGCCTCCACCTGCTCCCTCTCTCCTCACTGGCCTTTCTTTCCGTCTAGCTTCCTCTTCAGGAAATGTC CTGACTCCCCTCAGCTCCCCCTTCACCCCTCCTTGCCCGCCTACCCTCCCTCCAGAATAGCCCCTCACCCTTCTTCCCCTTCTAGTTGAT CCTTTTCACCTCCCTGATCCCCTTCATTTCTTCACCGCGGTTCCTCGTCATAGGGGTTCTCACTCTGAACTTTCCCTCTCTACTACCCAT GGCAGGAACCTAGTACAGGTCTCCCACCCAGGGCCTTCCACCCTCGGCTCCTGTGCTGGGAGAAACTTCCAGGCGTGGACAGCCCAGCCT GAGGCATTCCAGTGCTGGGGCACCGTCGCCTAACCTGGTTTCTAGCTTTGCCCTCACTCCCCGGAAAAACTGACACTGACACAGGGGCCC TTTCCTTGCCCCTTTAGCTGGTACCTCAGTGGGGAGGCTTCCTTACCAAGAATGAGTTCCTGAAACCCAGGGCCAGAGACAAGGACAACT TAGGGGAAGACGGGGTTTTCGGTGGAGCCAGGGGCAAATCTTAATGGGACCAGTGGGGGATACCCCAGAGCCCATGGCCTGACTGCACAG CCTGCCTGGAGGATGGGTGCGCAGCTCTGCCCTCCCTGAGGCCCAGGACTATGCCAGAAGCGATGGGGTACCGTGTAGGGGAGCCAAGGC CAGTAGTTTGGGGGTAGGAGTCCCCTAGAGTCTCAGAAGACTGGGCTCTTTGGAGTACAGGGTCCCCGGCCTCTCCTTTAAGATTCTCTC CCCAGCTGGAAGGCCGATGACTGGGTGGTCGGGAGGGAGACCCAGCTCTCCTTTCTGTCCCGTTTGCAGCACTGGTTTTGTTTCCTTAAT |
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FusionGenePPI for SLC43A2_SMG6 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SLC43A2 | ELAVL1, KRTAP10-3, YIPF3, TRIM25 | SMG6 | TERT, HDAC8, UPF1, HBB, PPP1CC, SOX2, RBM8A, MAGOH, PABPC1, SMG6, UPF3B, SMG5, SMG7, PSG1, C2orf68, FAM221B, SPATA1, HAO2, LPIN3, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000354901 | - | 0 | 12 | 114_503 | -99 | 512 | telomeric DNA |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000536871 | - | 0 | 11 | 114_503 | -81 | 512 | telomeric DNA |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000263073 | - | 5 | 19 | 114_503 | 779 | 1420 | telomeric DNA |
| Tgene | SMG6 | chr17:1516489 | chr17:2187029 | ENST00000544865 | - | 5 | 19 | 114_503 | 748 | 1389 | telomeric DNA |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SLC43A2_SMG6 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SLC43A2_SMG6 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SLC43A2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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