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Fusion gene ID: 34411 |
FusionGeneSummary for SLC38A2_C12orf4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC38A2_C12orf4 | Fusion gene ID: 34411 | Hgene | Tgene | Gene symbol | SLC38A2 | C12orf4 | Gene ID | 54407 | 57102 |
| Gene name | solute carrier family 38 member 2 | chromosome 12 open reading frame 4 | |
| Synonyms | ATA2|PRO1068|SAT2|SNAT2 | - | |
| Cytomap | 12q13.11 | 12p13.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sodium-coupled neutral amino acid transporter 2amino acid transporter 2amino acid transporter A2protein 40-9-1system A amino acid transporter 2system A transporter 1system N amino acid transporter 2 | protein C12orf4 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q96QD8 | Q9NQ89 | |
| Ensembl transtripts involved in fusion gene | ENST00000256689, ENST00000551374, ENST00000547252, | ENST00000261250, ENST00000545746, ENST00000509318, | |
| Fusion gene scores | * DoF score | 6 X 6 X 3=108 | 5 X 4 X 5=100 |
| # samples | 6 | 5 | |
| ** MAII score | log2(6/108*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SLC38A2 [Title/Abstract] AND C12orf4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-59-2348-01A | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000256689 | ENST00000261250 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| In-frame | ENST00000256689 | ENST00000545746 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| 5CDS-intron | ENST00000256689 | ENST00000509318 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| Frame-shift | ENST00000551374 | ENST00000261250 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| Frame-shift | ENST00000551374 | ENST00000545746 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| 5CDS-intron | ENST00000551374 | ENST00000509318 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| intron-3CDS | ENST00000547252 | ENST00000261250 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| intron-3CDS | ENST00000547252 | ENST00000545746 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
| intron-intron | ENST00000547252 | ENST00000509318 | SLC38A2 | chr12 | 46758172 | - | C12orf4 | chr12 | 4634749 | - |
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FusionProtFeatures for SLC38A2_C12orf4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC38A2 | C12orf4 |
| Functions as a sodium-dependent amino acid transporter.Mediates the saturable, pH-sensitive and electrogenic cotransportof neutral amino acids and sodium ions with a stoichiometry of1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetusthrough the placenta. {ECO:0000269|PubMed:10930503,ECO:0000269|PubMed:15922329}. | Plays a role in mast cell degranulation.{ECO:0000250|UniProtKB:D4A770}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 1_96 | 291 | 507 | Region | Regulates protein turnover upon amino acid deprivation |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 124_158 | 291 | 507 | Topological domain | Cytoplasmic |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 180_188 | 291 | 507 | Topological domain | Extracellular |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 1_76 | 291 | 507 | Topological domain | Cytoplasmic |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 210_217 | 291 | 507 | Topological domain | Cytoplasmic |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 239_292 | 291 | 507 | Topological domain | Extracellular |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 98_102 | 291 | 507 | Topological domain | Extracellular |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 103_123 | 291 | 507 | Transmembrane | Helical |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 159_179 | 291 | 507 | Transmembrane | Helical |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 189_209 | 291 | 507 | Transmembrane | Helical |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 218_238 | 291 | 507 | Transmembrane | Helical |
| Hgene | SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 77_97 | 291 | 507 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 314_329 | 291 | 507 | Topological domain | Cytoplasmic |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 351_371 | 291 | 507 | Topological domain | Extracellular |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 393_413 | 291 | 507 | Topological domain | Cytoplasmic |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 435_436 | 291 | 507 | Topological domain | Extracellular |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 458_474 | 291 | 507 | Topological domain | Cytoplasmic |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 496_506 | 291 | 507 | Topological domain | Extracellular |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 293_313 | 291 | 507 | Transmembrane | Helical |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 330_350 | 291 | 507 | Transmembrane | Helical |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 372_392 | 291 | 507 | Transmembrane | Helical |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 414_434 | 291 | 507 | Transmembrane | Helical |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 437_457 | 291 | 507 | Transmembrane | Helical |
| Hgene | >SLC38A2 | chr12:46758172 | chr12:4634749 | ENST00000256689 | - | 10 | 16 | 475_495 | 291 | 507 | Transmembrane | Helical |
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FusionGeneSequence for SLC38A2_C12orf4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SLC38A2_ENST00000256689_chr12_46758172_-_C12orf4_ENST00000261250_chr12_4634749_-_675aa MKKAEMGRFSISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGIL GLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQAL TNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPA LSHNVTENDSCRPHYFIFNSQTRYXNGKSHAGIGKITDRSRCKFTGCSAFXIPARPRKXMVEXIKTINCHPKTRVSRMGNKTSPRPKKPQ QQLPXXGNXSSAKSVQRICRSNWKDLXGTEKVRRKFYHSLRSPVEDHAXFEIAESRYAGLLXAXKKSSKWCETSSAPNSSVTLFYISLWP GFTSRXSNXFIXWYXKRFCHSLPRMHXLPFPPNXRAIRSCPTGGTLCXNPAQEXIERITXFWKPKWRKXXXDXECXEELFKCFTWGILYY TAFXSLRNPCCFPSLCGXPCEIGKHHCSXSCHYGTPKYTQSLLYPXHHNNKHSSLAGTXYVRGNDYTLVLKESGTCVQVCQRFHDGNGFM >In-frame_SLC38A2_ENST00000256689_chr12_46758172_-_C12orf4_ENST00000545746_chr12_4634749_-_675aa MKKAEMGRFSISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGIL GLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQAL TNIEDKTGLWYLNGNYLVLLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVEAALIINETINTTLTQPTALVPA LSHNVTENDSCRPHYFIFNSQTRYXNGKSHAGIGKITDRSRCKFTGCSAFXIPARPRKXMVEXIKTINCHPKTRVSRMGNKTSPRPKKPQ QQLPXXGNXSSAKSVQRICRSNWKDLXGTEKVRRKFYHSLRSPVEDHAXFEIAESRYAGLLXAXKKSSKWCETSSAPNSSVTLFYISLWP GFTSRXSNXFIXWYXKRFCHSLPRMHXLPFPPNXRAIRSCPTGGTLCXNPAQEXIERITXFWKPKWRKXXXDXECXEELFKCFTWGILYY TAFXSLRNPCCFPSLCGXPCEIGKHHCSXSCHYGTPKYTQSLLYPXHHNNKHSSLAGTXYVRGNDYTLVLKESGTCVQVCQRFHDGNGFM |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SLC38A2_ENST00000256689_chr12_46758172_-_C12orf4_ENST00000261250_chr12_4634749_-_2026nt ATGAAGAAGGCCGAAATGGGACGATTCAGTATTTCCCCGGATGAAGACAGCAGCAGCTACAGTTCCAACAGCGACTTCAACTACTCCTAC CCCACCAAGCAAGCTGCTCTGAAAAGCCATTATGCAGATGTAGATCCTGAAAACCAGAACTTTTTACTTGAATCGAATTTGGGGAAGAAG AAGTATGAAACAGAATTTCATCCAGGTACTACTTCCTTTGGAATGTCAGTATTTAATCTGAGCAATGCGATTGTGGGCAGTGGAATCCTT GGGCTTTCTTATGCCATGGCTAATACTGGAATTGCTCTTTTTATAATTCTCTTGACATTTGTGTCAATATTTTCCCTGTATTCTGTTCAT CTCCTTTTGAAGACTGCCAATGAAGGAGGGTCTTTATTATATGAACAATTGGGATATAAGGCATTTGGATTAGTTGGAAAGCTTGCAGCA TCTGGATCAATTACAATGCAGAACATTGGAGCTATGTCAAGCTACCTCTTCATAGTGAAATATGAGTTGCCTTTGGTGATCCAGGCATTA ACGAACATTGAAGATAAAACTGGATTGTGGTATCTGAACGGGAACTATTTGGTTCTGTTGGTGTCATTGGTGGTCATTCTTCCTTTGTCG CTGTTTAGAAATTTAGGATATTTGGGATATACCAGTGGCCTTTCCTTGTTGTGTATGGTGTTCTTTCTGATTGTGGTCATTTGCAAGAAA TTTCAGGTTCCGTGTCCTGTGGAAGCTGCTTTGATAATTAACGAAACAATAAACACCACCTTAACACAGCCAACAGCTCTTGTACCTGCT TTGTCACATAACGTGACTGAAAATGACTCTTGCAGACCTCACTATTTTATTTTCAACTCACAGACAAGGTATTGAAATGGAAAAAGTCAT GCAGGAATTGGGAAAATCACTGACAGATCAAGATGTAAATTCACTGGCTGCTCAGCATTTTGAATCCCAGCAAGACCTAGAAAATAAATG GTCGAATGAATTAAAACAATCAACTGCCATCCAAAAACAAGAGTATCAAGAATGGGTAATAAAACTTCACCAAGACCTAAAAAACCCCAA CAACAGCTCCCTTAGTGAGGAAATTAAAGTTCAGCCAAGTCAGTTCAGAGAATCTGTAGAAGCAATTGGAAGGATTTATGAGGAACAGAG AAAGTTAGAAGAAAGTTTTACCATTCACTTAGGAGCCCAGTTGAAGACCATGCATAATTTGAGATTGCTGAGAGCAGATATGCTGGACTT CTGTAAGCATAAAAGAAATCATCGAAGTGGTGTGAAACTTCATCGGCTCCAAACAGCTCTGTCACTTTATTCTACATCTCTCTGTGGCCT GGTTTTACTAGTAGATAATCGAATTAATTCATATAGTGGTATTAAAAGAGATTTTGCCACAGTTTGCCAAGAATGCACTGACTTCCATTT CCCCCGAATTGAAGAGCAATTAGAAGTTGTCCAACAGGTGGTACTTTATGCTAGAACCCAGCGCAGGAGTAAATTGAAAGAATCACTTGA TTCTGGAAACCAAAATGGAGGAAATGATGATAAGACTAAGAATGCTGAGAGGAACTATTTAAATGTTTTACCTGGGGAATTTTATATTAC ACGGCATTCTAATCTCTCAGAAATCCATGTTGCTTTCCATCTCTGTGTGGATGACCATGTGAAATCGGGAAACATCACTGCTCGTGATCC TGCCATTATGGGACTCCGAAATATACTCAAAGTTTGCTGTACCCATGACATCACAACAATAAGCATTCCTCTCTTGCTGGTACATGATAT GTCAGAGGAAATGACTATACCCTGGTGCTTAAGGAGAGCGGAACTTGTGTTCAAGTGTGTCAAAGGTTTCATGATGGAAATGGCTTCATG GGATGGAGGAATTTCTAGGACAGTGCAATTTCTAGTACCACAGAGTATTTCTGAAGAAATGTTTTATCAACTTAGTAACATGCTTCCCCA >In-frame_SLC38A2_ENST00000256689_chr12_46758172_-_C12orf4_ENST00000545746_chr12_4634749_-_2026nt ATGAAGAAGGCCGAAATGGGACGATTCAGTATTTCCCCGGATGAAGACAGCAGCAGCTACAGTTCCAACAGCGACTTCAACTACTCCTAC CCCACCAAGCAAGCTGCTCTGAAAAGCCATTATGCAGATGTAGATCCTGAAAACCAGAACTTTTTACTTGAATCGAATTTGGGGAAGAAG AAGTATGAAACAGAATTTCATCCAGGTACTACTTCCTTTGGAATGTCAGTATTTAATCTGAGCAATGCGATTGTGGGCAGTGGAATCCTT GGGCTTTCTTATGCCATGGCTAATACTGGAATTGCTCTTTTTATAATTCTCTTGACATTTGTGTCAATATTTTCCCTGTATTCTGTTCAT CTCCTTTTGAAGACTGCCAATGAAGGAGGGTCTTTATTATATGAACAATTGGGATATAAGGCATTTGGATTAGTTGGAAAGCTTGCAGCA TCTGGATCAATTACAATGCAGAACATTGGAGCTATGTCAAGCTACCTCTTCATAGTGAAATATGAGTTGCCTTTGGTGATCCAGGCATTA ACGAACATTGAAGATAAAACTGGATTGTGGTATCTGAACGGGAACTATTTGGTTCTGTTGGTGTCATTGGTGGTCATTCTTCCTTTGTCG CTGTTTAGAAATTTAGGATATTTGGGATATACCAGTGGCCTTTCCTTGTTGTGTATGGTGTTCTTTCTGATTGTGGTCATTTGCAAGAAA TTTCAGGTTCCGTGTCCTGTGGAAGCTGCTTTGATAATTAACGAAACAATAAACACCACCTTAACACAGCCAACAGCTCTTGTACCTGCT TTGTCACATAACGTGACTGAAAATGACTCTTGCAGACCTCACTATTTTATTTTCAACTCACAGACAAGGTATTGAAATGGAAAAAGTCAT GCAGGAATTGGGAAAATCACTGACAGATCAAGATGTAAATTCACTGGCTGCTCAGCATTTTGAATCCCAGCAAGACCTAGAAAATAAATG GTCGAATGAATTAAAACAATCAACTGCCATCCAAAAACAAGAGTATCAAGAATGGGTAATAAAACTTCACCAAGACCTAAAAAACCCCAA CAACAGCTCCCTTAGTGAGGAAATTAAAGTTCAGCCAAGTCAGTTCAGAGAATCTGTAGAAGCAATTGGAAGGATTTATGAGGAACAGAG AAAGTTAGAAGAAAGTTTTACCATTCACTTAGGAGCCCAGTTGAAGACCATGCATAATTTGAGATTGCTGAGAGCAGATATGCTGGACTT CTGTAAGCATAAAAGAAATCATCGAAGTGGTGTGAAACTTCATCGGCTCCAAACAGCTCTGTCACTTTATTCTACATCTCTCTGTGGCCT GGTTTTACTAGTAGATAATCGAATTAATTCATATAGTGGTATTAAAAGAGATTTTGCCACAGTTTGCCAAGAATGCACTGACTTCCATTT CCCCCGAATTGAAGAGCAATTAGAAGTTGTCCAACAGGTGGTACTTTATGCTAGAACCCAGCGCAGGAGTAAATTGAAAGAATCACTTGA TTCTGGAAACCAAAATGGAGGAAATGATGATAAGACTAAGAATGCTGAGAGGAACTATTTAAATGTTTTACCTGGGGAATTTTATATTAC ACGGCATTCTAATCTCTCAGAAATCCATGTTGCTTTCCATCTCTGTGTGGATGACCATGTGAAATCGGGAAACATCACTGCTCGTGATCC TGCCATTATGGGACTCCGAAATATACTCAAAGTTTGCTGTACCCATGACATCACAACAATAAGCATTCCTCTCTTGCTGGTACATGATAT GTCAGAGGAAATGACTATACCCTGGTGCTTAAGGAGAGCGGAACTTGTGTTCAAGTGTGTCAAAGGTTTCATGATGGAAATGGCTTCATG GGATGGAGGAATTTCTAGGACAGTGCAATTTCTAGTACCACAGAGTATTTCTGAAGAAATGTTTTATCAACTTAGTAACATGCTTCCCCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SLC38A2_ENST00000256689_chr12_46758172_-_C12orf4_ENST00000261250_chr12_4634749_-_4550nt GATACACAAAGAGAAGGCGCCCGGGCGGCCGCGGTCCCGCCCACTGACGCGTCCCCGGGGTGCCGCTATAACCCGCCGCTCGCAGGGCTG CTCCACAGCCGCGCGACGCCGCCGCCTTAGAACGCCTTTCCAGTACTGCTAGCAGCAGCCCGACCACGCGTTACCGCACGCTCGCGCCTT TCCCTTGACACGGCGGACGCCGGAGGATTGGGGCGGCAATTTGTCTTTTCCTTTTTTATTAAAATTATTTTTCCTGCCTGTTGTTGGATT TGGGGAAATTTTTTGTTTGTTTTTTATGATTTGTATTTGACTGAGAGAAACCCACTGAAGACGTCTGCGTGAGAATAGAGACCACCGAGG CCGACTCGCGGGCCGCTGCACCCACCGCCAAGGACAAAAGGAGCCCAGCGCTACTAGCTGCACCCGATTCCTCCCAGTGCTTAGCATGAA GAAGGCCGAAATGGGACGATTCAGTATTTCCCCGGATGAAGACAGCAGCAGCTACAGTTCCAACAGCGACTTCAACTACTCCTACCCCAC CAAGCAAGCTGCTCTGAAAAGCCATTATGCAGATGTAGATCCTGAAAACCAGAACTTTTTACTTGAATCGAATTTGGGGAAGAAGAAGTA TGAAACAGAATTTCATCCAGGTACTACTTCCTTTGGAATGTCAGTATTTAATCTGAGCAATGCGATTGTGGGCAGTGGAATCCTTGGGCT TTCTTATGCCATGGCTAATACTGGAATTGCTCTTTTTATAATTCTCTTGACATTTGTGTCAATATTTTCCCTGTATTCTGTTCATCTCCT TTTGAAGACTGCCAATGAAGGAGGGTCTTTATTATATGAACAATTGGGATATAAGGCATTTGGATTAGTTGGAAAGCTTGCAGCATCTGG ATCAATTACAATGCAGAACATTGGAGCTATGTCAAGCTACCTCTTCATAGTGAAATATGAGTTGCCTTTGGTGATCCAGGCATTAACGAA CATTGAAGATAAAACTGGATTGTGGTATCTGAACGGGAACTATTTGGTTCTGTTGGTGTCATTGGTGGTCATTCTTCCTTTGTCGCTGTT TAGAAATTTAGGATATTTGGGATATACCAGTGGCCTTTCCTTGTTGTGTATGGTGTTCTTTCTGATTGTGGTCATTTGCAAGAAATTTCA GGTTCCGTGTCCTGTGGAAGCTGCTTTGATAATTAACGAAACAATAAACACCACCTTAACACAGCCAACAGCTCTTGTACCTGCTTTGTC ACATAACGTGACTGAAAATGACTCTTGCAGACCTCACTATTTTATTTTCAACTCACAGACAAGGTATTGAAATGGAAAAAGTCATGCAGG AATTGGGAAAATCACTGACAGATCAAGATGTAAATTCACTGGCTGCTCAGCATTTTGAATCCCAGCAAGACCTAGAAAATAAATGGTCGA ATGAATTAAAACAATCAACTGCCATCCAAAAACAAGAGTATCAAGAATGGGTAATAAAACTTCACCAAGACCTAAAAAACCCCAACAACA GCTCCCTTAGTGAGGAAATTAAAGTTCAGCCAAGTCAGTTCAGAGAATCTGTAGAAGCAATTGGAAGGATTTATGAGGAACAGAGAAAGT TAGAAGAAAGTTTTACCATTCACTTAGGAGCCCAGTTGAAGACCATGCATAATTTGAGATTGCTGAGAGCAGATATGCTGGACTTCTGTA AGCATAAAAGAAATCATCGAAGTGGTGTGAAACTTCATCGGCTCCAAACAGCTCTGTCACTTTATTCTACATCTCTCTGTGGCCTGGTTT TACTAGTAGATAATCGAATTAATTCATATAGTGGTATTAAAAGAGATTTTGCCACAGTTTGCCAAGAATGCACTGACTTCCATTTCCCCC GAATTGAAGAGCAATTAGAAGTTGTCCAACAGGTGGTACTTTATGCTAGAACCCAGCGCAGGAGTAAATTGAAAGAATCACTTGATTCTG GAAACCAAAATGGAGGAAATGATGATAAGACTAAGAATGCTGAGAGGAACTATTTAAATGTTTTACCTGGGGAATTTTATATTACACGGC ATTCTAATCTCTCAGAAATCCATGTTGCTTTCCATCTCTGTGTGGATGACCATGTGAAATCGGGAAACATCACTGCTCGTGATCCTGCCA TTATGGGACTCCGAAATATACTCAAAGTTTGCTGTACCCATGACATCACAACAATAAGCATTCCTCTCTTGCTGGTACATGATATGTCAG AGGAAATGACTATACCCTGGTGCTTAAGGAGAGCGGAACTTGTGTTCAAGTGTGTCAAAGGTTTCATGATGGAAATGGCTTCATGGGATG GAGGAATTTCTAGGACAGTGCAATTTCTAGTACCACAGAGTATTTCTGAAGAAATGTTTTATCAACTTAGTAACATGCTTCCCCAGATCT TCCGAGTATCATCAACACTCACTCTGACATCCAAGCACTAAACCCTTATAGATTGACATGCTGGCAGAAGATGATTGTTAAACTCTCCAG GAACTTGTGCTATGCTGGGAATCTGTCAAGCAAAAGATGCCCAGAAAGAGAACTTGCAGCTCAATCCACAAATCAAGATACATGTGTGTG AAACCATTCCAAAAATTTATATACTGCACAAACTGGTGATCAACCCCTAACTTAAACACTTAAAGTCTCTTTATGAATTTCTCTTTTTTT CTTCTCTGTGTTACCTGTGAATATTAGTAATCTAAAACTTTTTATTTATCACACATGGACACTTGGGAAAGGAAACTTGATTATATTTAC ATGGAGGCATTTGACTTTTTCAAGAGGCTTGACTCGTCTCAGGTGCAATCCTTAATTAAACATACAAACAAAATTTTCCTTTTACTTTCT TTGCCAAAACAAAATGTAAAAGCACTGAAATATACATTGCAAGTACAAATTTCCTGTGAAAATCTTTTTATAGAAACACAAATGTATAAG ACAAATGTGCTTGTTCTTTTAAATTCTCCTGTTTCAGAATCTCTTTTTAATCTACTCCTAAGGATGTACAAGTTAGAGTCAGAAGACGTT TTGGATTTTTTCCCTCTCTCTCATCCTCCCGCTGTGCCCTTGCACTTGCATATTAATAACATTTCATGGACTGGGAAATAGTGTTCTTTT TTGCAAGCTTGATGTCAAGTTAGTCTAAACCAGCACCTGGCAGTATTTTAGTGCTCATCAACATTGTGACAATCACACAAGGAAGATCAT TTCTACATTTCTGTCCTCCCTGCGTTCTCAGCTTGCTTAACCATTCCTCTACCTCTTGCATTTTTTTGCGGATAAATGTATCCCCATTTC TGCTTCTCTGTTTCCCCTCCTTTTCCATTGTTTTTCCTTATGGTACTACTTTCTCAGGTGCTACATATCATATATTTGTCCCATCTATAA CATATTTAAATGCTATAAGTAGTAACTCCATTAAACAAAGGCATTTACAAAAGCACACAGGTGTTTAGAAAAGCAATAGTTTCATCAATT CCAAGTTATGTGGATATTGTAACTGGCCACAAGAATGAAATGGAGGGCATTTGGTGTCATAAGATGGCATGTCTTGATGACAAGAAACAA AACGCCCTTCATTAATATGCCTCAGTGTAATAACTATTATAGAAACTGTTGGCAAGCAGAGTGCTTTCCTATAACAGAATGTGTCTTAAT TTTCTACTCGAGGGAAAGGTTTGTCCAGGTAACAACACTAAAGACAACCCTAAGAACACCCACTCCAGCAGTATGTCCATTAGACACTAA AACTCTCCAAATTATTTGTCAGGGAGCCTGGCGATTCTGCCAAGAAGGCAGGTGTTTTGCCCTTAGAGCCTATACAGTTCTCTTGGAGAA ATTGTCTTTCAGGCACCACTGTTAATCACTGAGACTGATTCTAATGCAAAGCAGGGAAGACAGAGGCAGAAACCAGGAGAGTGGTAGATC AGTGCAGCCCAGATATCGGAATGGAGGAGCAAAGTTTCATTCACGGATGTTTGTTGAATGCTGCTGCCCAACTCTTCCTTTGTCACCTCT AGGCTATTCCACTAAGTTACTTATAAACTGGTGGCTTTAACTGAGGGCTGTGTAAAGGTACTATTTGGCATGTGAAGTCAGGATAAATTT ATCGAATGTCCGTTTTCCACATGCAACTGTGTTACAGAAGTAGTAAAATTGGAAGAATCATGTTTATGGTGTTACCACTGATGGAAACAC ACAAACACCAAGCTAATAATAAATATATAACTTAAAAAGCTAATTATATGCACTGAAATGGTGGGAATTTTAGTGATGCAGTAATTGAGG AGTCTGGAGTTTTGTATTTGGACCAAGAATTATGAGATGAGGATCTTTTTCTGAGTGTTCTAAAGGGCTTCTTGAGGGGGAGTGGTTTAA AGCACTTCATGAATGATGTGAAGAAGGTACCTTGGGCTGAGACAGCATTCTAGGTACAGATGGCACTCTGTTCAACCAACTGTGGATGGA >In-frame_SLC38A2_ENST00000256689_chr12_46758172_-_C12orf4_ENST00000545746_chr12_4634749_-_2863nt GATACACAAAGAGAAGGCGCCCGGGCGGCCGCGGTCCCGCCCACTGACGCGTCCCCGGGGTGCCGCTATAACCCGCCGCTCGCAGGGCTG CTCCACAGCCGCGCGACGCCGCCGCCTTAGAACGCCTTTCCAGTACTGCTAGCAGCAGCCCGACCACGCGTTACCGCACGCTCGCGCCTT TCCCTTGACACGGCGGACGCCGGAGGATTGGGGCGGCAATTTGTCTTTTCCTTTTTTATTAAAATTATTTTTCCTGCCTGTTGTTGGATT TGGGGAAATTTTTTGTTTGTTTTTTATGATTTGTATTTGACTGAGAGAAACCCACTGAAGACGTCTGCGTGAGAATAGAGACCACCGAGG CCGACTCGCGGGCCGCTGCACCCACCGCCAAGGACAAAAGGAGCCCAGCGCTACTAGCTGCACCCGATTCCTCCCAGTGCTTAGCATGAA GAAGGCCGAAATGGGACGATTCAGTATTTCCCCGGATGAAGACAGCAGCAGCTACAGTTCCAACAGCGACTTCAACTACTCCTACCCCAC CAAGCAAGCTGCTCTGAAAAGCCATTATGCAGATGTAGATCCTGAAAACCAGAACTTTTTACTTGAATCGAATTTGGGGAAGAAGAAGTA TGAAACAGAATTTCATCCAGGTACTACTTCCTTTGGAATGTCAGTATTTAATCTGAGCAATGCGATTGTGGGCAGTGGAATCCTTGGGCT TTCTTATGCCATGGCTAATACTGGAATTGCTCTTTTTATAATTCTCTTGACATTTGTGTCAATATTTTCCCTGTATTCTGTTCATCTCCT TTTGAAGACTGCCAATGAAGGAGGGTCTTTATTATATGAACAATTGGGATATAAGGCATTTGGATTAGTTGGAAAGCTTGCAGCATCTGG ATCAATTACAATGCAGAACATTGGAGCTATGTCAAGCTACCTCTTCATAGTGAAATATGAGTTGCCTTTGGTGATCCAGGCATTAACGAA CATTGAAGATAAAACTGGATTGTGGTATCTGAACGGGAACTATTTGGTTCTGTTGGTGTCATTGGTGGTCATTCTTCCTTTGTCGCTGTT TAGAAATTTAGGATATTTGGGATATACCAGTGGCCTTTCCTTGTTGTGTATGGTGTTCTTTCTGATTGTGGTCATTTGCAAGAAATTTCA GGTTCCGTGTCCTGTGGAAGCTGCTTTGATAATTAACGAAACAATAAACACCACCTTAACACAGCCAACAGCTCTTGTACCTGCTTTGTC ACATAACGTGACTGAAAATGACTCTTGCAGACCTCACTATTTTATTTTCAACTCACAGACAAGGTATTGAAATGGAAAAAGTCATGCAGG AATTGGGAAAATCACTGACAGATCAAGATGTAAATTCACTGGCTGCTCAGCATTTTGAATCCCAGCAAGACCTAGAAAATAAATGGTCGA ATGAATTAAAACAATCAACTGCCATCCAAAAACAAGAGTATCAAGAATGGGTAATAAAACTTCACCAAGACCTAAAAAACCCCAACAACA GCTCCCTTAGTGAGGAAATTAAAGTTCAGCCAAGTCAGTTCAGAGAATCTGTAGAAGCAATTGGAAGGATTTATGAGGAACAGAGAAAGT TAGAAGAAAGTTTTACCATTCACTTAGGAGCCCAGTTGAAGACCATGCATAATTTGAGATTGCTGAGAGCAGATATGCTGGACTTCTGTA AGCATAAAAGAAATCATCGAAGTGGTGTGAAACTTCATCGGCTCCAAACAGCTCTGTCACTTTATTCTACATCTCTCTGTGGCCTGGTTT TACTAGTAGATAATCGAATTAATTCATATAGTGGTATTAAAAGAGATTTTGCCACAGTTTGCCAAGAATGCACTGACTTCCATTTCCCCC GAATTGAAGAGCAATTAGAAGTTGTCCAACAGGTGGTACTTTATGCTAGAACCCAGCGCAGGAGTAAATTGAAAGAATCACTTGATTCTG GAAACCAAAATGGAGGAAATGATGATAAGACTAAGAATGCTGAGAGGAACTATTTAAATGTTTTACCTGGGGAATTTTATATTACACGGC ATTCTAATCTCTCAGAAATCCATGTTGCTTTCCATCTCTGTGTGGATGACCATGTGAAATCGGGAAACATCACTGCTCGTGATCCTGCCA TTATGGGACTCCGAAATATACTCAAAGTTTGCTGTACCCATGACATCACAACAATAAGCATTCCTCTCTTGCTGGTACATGATATGTCAG AGGAAATGACTATACCCTGGTGCTTAAGGAGAGCGGAACTTGTGTTCAAGTGTGTCAAAGGTTTCATGATGGAAATGGCTTCATGGGATG GAGGAATTTCTAGGACAGTGCAATTTCTAGTACCACAGAGTATTTCTGAAGAAATGTTTTATCAACTTAGTAACATGCTTCCCCAGATCT TCCGAGTATCATCAACACTCACTCTGACATCCAAGCACTAAACCCTTATAGATTGACATGCTGGCAGAAGATGATTGTTAAACTCTCCAG GAACTTGTGCTATGCTGGGAATCTGTCAAGCAAAAGATGCCCAGAAAGAGAACTTGCAGCTCAATCCACAAATCAAGATACATGTGTGTG AAACCATTCCAAAAATTTATATACTGCACAAACTGGTGATCAACCCCTAACTTAAACACTTAAAGTCTCTTTATGAATTTCTCTTTTTTT CTTCTCTGTGTTACCTGTGAATATTAGTAATCTAAAACTTTTTATTTATCACACATGGACACTTGGGAAAGGAAACTTGATTATATTTAC |
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FusionGenePPI for SLC38A2_C12orf4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SLC38A2 | STX11, ELAVL1, APP, FLOT1, MCU, COX5A, UNK, TCTN3, TMEM17, TMEM216, CDC42, GJB2, KIF20B, ATP6AP2, GOLT1B, TMEM63B, CHMP4B, TSPAN5, LPAR6, DLK1 | C12orf4 | PPP1R21, IL6R, TCP10L |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SLC38A2_C12orf4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SLC38A2_C12orf4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SLC38A2 | C0036341 | Schizophrenia | 1 | PSYGENET |
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