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Fusion gene ID: 34295 |
FusionGeneSummary for SLC2A12_ZNF236 |
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Fusion gene information | Fusion gene name: SLC2A12_ZNF236 | Fusion gene ID: 34295 | Hgene | Tgene | Gene symbol | SLC2A12 | ZNF236 | Gene ID | 154091 | 7776 |
Gene name | solute carrier family 2 member 12 | zinc finger protein 236 | |
Synonyms | GLUT12|GLUT8 | ZNF236A|ZNF236B | |
Cytomap | 6q23.2 | 18q23 | |
Type of gene | protein-coding | protein-coding | |
Description | solute carrier family 2, facilitated glucose transporter member 12GLUT-12glucose transporter type 12solute carrier family 2 (facilitated glucose transporter), member 12 | zinc finger protein 236regulated by glucose | |
Modification date | 20180523 | 20180519 | |
UniProtAcc | Q8TD20 | Q9UL36 | |
Ensembl transtripts involved in fusion gene | ENST00000275230, | ENST00000320610, ENST00000253159, ENST00000583095, | |
Fusion gene scores | * DoF score | 3 X 3 X 4=36 | 3 X 3 X 1=9 |
# samples | 4 | 3 | |
** MAII score | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: SLC2A12 [Title/Abstract] AND ZNF236 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AA665574 | SLC2A12 | chr6 | 134311343 | + | ZNF236 | chr18 | 74625855 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000275230 | ENST00000320610 | SLC2A12 | chr6 | 134311343 | + | ZNF236 | chr18 | 74625855 | - |
intron-intron | ENST00000275230 | ENST00000253159 | SLC2A12 | chr6 | 134311343 | + | ZNF236 | chr18 | 74625855 | - |
intron-intron | ENST00000275230 | ENST00000583095 | SLC2A12 | chr6 | 134311343 | + | ZNF236 | chr18 | 74625855 | - |
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FusionProtFeatures for SLC2A12_ZNF236 |
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Hgene | Tgene |
SLC2A12 | ZNF236 |
Facilitative glucose transporter. {ECO:0000250}. | May be involved in transcriptional regulation. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for SLC2A12_ZNF236 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for SLC2A12_ZNF236 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SLC2A12_ZNF236 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SLC2A12_ZNF236 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |