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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 34178

FusionGeneSummary for SLC25A13_CD2AP

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC25A13_CD2AP
Fusion gene ID: 34178
HgeneTgene
Gene symbol

SLC25A13

CD2AP

Gene ID

10165

23607

Gene namesolute carrier family 25 member 13CD2 associated protein
SynonymsARALAR2|CITRIN|CTLN2CMS
Cytomap

7q21.3

6p12.3

Type of geneprotein-codingprotein-coding
Descriptioncalcium-binding mitochondrial carrier protein Aralar2mitochondrial aspartate glutamate carrier 2solute carrier family 25 (aspartate/glutamate carrier), member 13CD2-associated proteinCas ligand with multiple Src homology 3 (SH3) domainsadapter protein CMScas ligand with multiple SH3 domains
Modification date2018052320180522
UniProtAcc

Q9UJS0

Q9Y5K6

Ensembl transtripts involved in fusion geneENST00000265631, ENST00000416240, 
ENST00000542654, ENST00000494085, 
ENST00000359314, ENST00000486693, 
Fusion gene scores* DoF score9 X 7 X 8=5047 X 7 X 5=245
# samples 87
** MAII scorelog2(8/504*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC25A13 [Title/Abstract] AND CD2AP [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLC25A13

GO:0006754

ATP biosynthetic process

12851387

HgeneSLC25A13

GO:0015810

aspartate transmembrane transport

11566871

HgeneSLC25A13

GO:0015813

L-glutamate transmembrane transport

11566871

HgeneSLC25A13

GO:0043490

malate-aspartate shuttle

11566871

HgeneSLC25A13

GO:0045333

cellular respiration

12851387

HgeneSLC25A13

GO:0051592

response to calcium ion

11566871


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVREADTCGA-EI-6510-01ASLC25A13chr7

95813589

-CD2APchr6

47512342

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000265631ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
5CDS-intronENST00000265631ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+
In-frameENST00000416240ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
5CDS-intronENST00000416240ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+
Frame-shiftENST00000542654ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
5CDS-intronENST00000542654ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+
intron-3CDSENST00000494085ENST00000359314SLC25A13chr7

95813589

-CD2APchr6

47512342

+
intron-intronENST00000494085ENST00000486693SLC25A13chr7

95813589

-CD2APchr6

47512342

+

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FusionProtFeatures for SLC25A13_CD2AP


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SLC25A13

Q9UJS0

CD2AP

Q9Y5K6

Mitochondrial and calcium-binding carrier that catalyzesthe calcium-dependent exchange of cytoplasmic glutamate withmitochondrial aspartate across the mitochondrial inner membrane(PubMed:11566871, PubMed:25410934). May have a function in theurea cycle (PubMed:11566871). {ECO:0000269|PubMed:11566871,ECO:0000269|PubMed:25410934}. Seems to act as an adapter protein between membraneproteins and the actin cytoskeleton (PubMed:10339567). Incollaboration with CBLC, modulates the rate of RET turnover andmay act as regulatory checkpoint that limits the potency of GDNFon neuronal survival. Controls CBLC function, converting it froman inhibitor to a promoter of RET degradation (By similarity). Mayplay a role in receptor clustering and cytoskeletal polarity inthe junction between T-cell and antigen-presenting cell (Bysimilarity). May anchor the podocyte slit diaphragm to the actincytoskeleton in renal glomerolus. Also required for cytokinesis(PubMed:15800069). Plays a role in epithelial cell junctionsformation (PubMed:22891260). {ECO:0000250|UniProtKB:F1LRS8,ECO:0000250|UniProtKB:Q9JLQ0, ECO:0000269|PubMed:10339567,ECO:0000269|PubMed:15800069, ECO:0000269|PubMed:22891260}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118100_111392676Calcium bindingNote=2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118171_182392676Calcium bindingNote=3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-111866_77392676Calcium binding1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118100_111393677Calcium bindingNote=2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118171_182393677Calcium bindingNote=3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-111866_77393677Calcium binding1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118125_157392676DomainEF-hand 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118158_193392676DomainEF-hand 4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-111851_86392676DomainEF-hand 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-111887_122392676DomainEF-hand 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118125_157393677DomainEF-hand 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118158_193393677DomainEF-hand 4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-111851_86393677DomainEF-hand 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-111887_122393677DomainEF-hand 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118296_311392676RegionLinker loop domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-11182_295392676RegionN-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118296_311393677RegionLinker loop domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-11182_295393677RegionN-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118332_349392676TransmembraneHelical%3B Name%3D1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118332_349393677TransmembraneHelical%3B Name%3D1
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+218577_638106640Coiled coilOntology_term=ECO:0000255
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+218336_422106640Compositional biasNote=Pro-rich
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+218108_167106640DomainSH3 2
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+218269_330106640DomainSH3 3
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+218336_352106640MotifSH3-binding
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+218378_397106640MotifSH3-binding
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+218410_422106640MotifSH3-binding

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118321_612392676RegionCarrier domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118613_675392676RegionC-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118321_612393677RegionCarrier domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118613_675393677RegionC-terminal domain
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118326_418392676RepeatSolcar 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118426_510392676RepeatSolcar 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118518_606392676RepeatSolcar 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118326_418393677RepeatSolcar 1
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118426_510393677RepeatSolcar 2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118518_606393677RepeatSolcar 3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118393_412392676TransmembraneHelical%3B Name%3D2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118436_449392676TransmembraneHelical%3B Name%3D3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118485_504392676TransmembraneHelical%3B Name%3D4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118524_541392676TransmembraneHelical%3B Name%3D5
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000265631-1118581_600392676TransmembraneHelical%3B Name%3D6
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118393_412393677TransmembraneHelical%3B Name%3D2
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118436_449393677TransmembraneHelical%3B Name%3D3
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118485_504393677TransmembraneHelical%3B Name%3D4
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118524_541393677TransmembraneHelical%3B Name%3D5
HgeneSLC25A13chr7:95813589chr6:47512342ENST00000416240-1118581_600393677TransmembraneHelical%3B Name%3D6
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+2181_59106640DomainSH3 1%3B truncated


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FusionGeneSequence for SLC25A13_CD2AP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SLC25A13_ENST00000265631_chr7_95813589_-_CD2AP_ENST00000359314_chr6_47512342_+_926aa
MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDA
LFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA
IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGTRKDVEVTKEEFVLAAQKFGQVTPMEVD
ILFQLADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQR
STGSFVGELMYKNSFDCFKKVLRYEGFFGLYRETKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKE
LEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPKT
QSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPP
AKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSIS
SKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKE
EDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKD

>In-frame_SLC25A13_ENST00000416240_chr7_95813589_-_CD2AP_ENST00000359314_chr6_47512342_+_927aa
MAAAKVALTKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDA
LFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEFTQFLLEIQLEHAKQAFVQRDNARTGRVTA
IDFRDIMVTIRPHVLTPFVEECLVAAAGGTTSHQVSFSYFNGFNSLLNNMELIRKIYSTLAGTRKDVEVTKEEFVLAAQKFGQVTPMEVD
ILFQLADLYEPRGRMTLADIERIAPLEEGTLPFNLAEAQRQQKASGDSARPVLLQVAESAYRFGLGSVAGAVGATAVYPIDLVKTRMQNQ
RSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRETKKRQCKVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVK
ELEVTDDGETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKKPEKPLILQSLGPK
TQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPP
PAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSI
SSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPK
EEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRK


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SLC25A13_ENST00000265631_chr7_95813589_-_CD2AP_ENST00000359314_chr6_47512342_+_2778nt
ATGGCGGCCGCCAAGGTGGCTTTAACCAAGAGAGCAGATCCAGCTGAGCTTAGAACAATATTTTTGAAGTATGCAAGCATTGAGAAAAAC
GGTGAATTTTTCATGTCCCCCAATGACTTTGTCACTCGATACTTGAACATTTTTGGAGAAAGCCAGCCTAATCCAAAGACTGTGGAACTT
TTAAGTGGAGTGGTGGATCAGACCAAAGATGGATTAATATCTTTTCAAGAATTTGTTGCCTTTGAATCTGTCCTGTGTGCCCCTGATGCT
TTGTTTATGGTAGCCTTTCAGCTGTTTGACAAAGCTGGCAAAGGAGAAGTAACTTTTGAGGATGTTAAGCAAGTTTTTGGACAGACCACA
ATTCATCAACATATTCCATTTAACTGGGATTCAGAATTTGTGCAACTACATTTTGGAAAAGAAAGAAAAAGACACCTGACATATGCGGAA
TTTACTCAGTTTTTATTGGAAATACAACTGGAGCACGCAAAGCAAGCCTTTGTGCAACGGGACAATGCTAGGACTGGGAGAGTCACAGCC
ATCGACTTCCGAGACATCATGGTCACCATCCGCCCCCATGTCTTGACTCCTTTTGTAGAAGAATGTCTAGTAGCTGCTGCTGGAGGTACC
ACATCCCATCAAGTTAGTTTCTCCTATTTTAATGGATTTAATTCGCTCCTTAACAACATGGAACTCATTAGAAAGATCTATAGCACTCTG
GCTGGCACCAGGAAAGATGTTGAAGTGACTAAGGAGGAGTTTGTTCTGGCAGCTCAGAAATTTGGTCAGGTTACACCCATGGAAGTTGAC
ATCTTGTTTCAGTTAGCAGATTTATATGAGCCAAGGGGACGTATGACCTTAGCAGACATTGAACGGATTGCTCCTCTGGAAGAGGGAACT
CTGCCCTTTAACTTGGCTGAGGCCCAGAGGCAGAAGGCCTCAGGTGATTCAGCTCGACCAGTTCTTCTACAAGTTGCAGAGTCGGCCTAC
AGGTTTGGTCTGGGTTCTGTTGCTGGAGCTGTTGGAGCCACTGCTGTGTATCCTATCGATCTTGTAAAAACTCGAATGCAGAACCAACGA
TCAACTGGCTCTTTTGTGGGAGAACTCATGTATAAAAACAGCTTTGACTGTTTTAAGAAAGTGCTACGCTATGAAGGCTTCTTTGGACTG
TATAGAGAGACCAAGAAGCGTCAGTGTAAAGTTCTTTTTGAGTACATTCCACAAAATGAGGATGAACTGGAGCTGAAAGTGGGAGATATT
ATTGATATTAATGAAGAGGTAGAAGAAGGCTGGTGGAGTGGAACCCTGAATAACAAGTTGGGACTGTTTCCCTCAAATTTTGTGAAAGAA
TTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACGATTCAGAAACTGTTTTGGCTGGGCCTACTTCACCTATACCTTCTCTG
GGAAATGTGAGTGAAACTGCATCTGGATCAGTTACACAGCCAAAGAAAATTCGAGGAATTGGATTTGGAGACATTTTTAAAGAAGGCTCT
GTGAAACTTCGGACAAGAACATCCAGTAGTGAAACAGAAGAGAAAAAACCAGAAAAGCCCTTAATCCTACAGTCACTGGGACCCAAAACT
CAGAGTGTGGAGATAACAAAAACAGATACCGAAGGTAAAATTAAAGCTAAAGAATATTGTAGAACATTATTTGCCTATGAAGGTACTAAT
GAAGATGAACTTACTTTTAAAGAGGGGGAGATAATCCATTTGATAAGTAAGGAGACTGGAGAAGCTGGCTGGTGGAGGGGCGAACTTAAT
GGTAAAGAAGGAGTATTTCCAGACAATTTTGCTGTCCAGATAAATGAACTTGATAAAGACTTTCCAAAACCAAAGAAACCACCACCTCCT
GCTAAGGCTCCAGCTCCAAAGCCTGAACTGATAGCTGCAGAGAAGAAATATTTTTCTTTAAAGCCTGAAGAAAAGGATGAAAAATCAACA
CTGGAACAGAAACCTTCTAAACCAGCAGCTCCACAAGTCCCACCCAAGAAACCTACTCCACCTACCAAAGCCAGTAATTTACTGAGATCT
TCTGGAACAGTGTACCCAAAGCGACCTGAAAAACCAGTTCCTCCACCACCTCCTATAGCCAAGATTAATGGGGAAGTTTCTAGCATTTCA
TCAAAATTTGAAACTGAGCCAGTATCAAAACTAAAGCTAGATTCTGAACAGCTGCCCCTTAGACCAAAATCAGTAGACTTTGATTCACTT
ACAGTAAGGACCTCCAAAGAAACAGATGTTGTAAATTTTGATGACATAGCTTCCTCAGAAAACTTGCTTCATCTCACTGCAAATAGACCA
AAGATGCCTGGAAGAAGGTTGCCGGGCCGTTTCAATGGTGGACATTCTCCAACTCACAGCCCCGAAAAAATCTTGAAGTTACCAAAAGAA
GAAGACAGTGCCAACCTGAAGCCATCTGAATTAAAAAAAGATACATGCTACTCTCCAAAGCCATCTGTGTACCTTTCAACACCTTCCAGT
GCTTCTAAAGCAAATACAACTGCTTTCCTGACTCCATTAGAAATCAAAGCTAAAGTGGAAACAGATGATGTGAAAAAAAATTCCCTGGAT
GAACTTAGAGCCCAGATTATTGAATTGTTGTGCATTGTAGAAGCACTGAAAAAGGATCACGGGAAAGAACTGGAAAAACTGCGAAAAGAT

>In-frame_SLC25A13_ENST00000416240_chr7_95813589_-_CD2AP_ENST00000359314_chr6_47512342_+_2781nt
ATGGCGGCCGCCAAGGTGGCTTTAACCAAGAGAGCAGATCCAGCTGAGCTTAGAACAATATTTTTGAAGTATGCAAGCATTGAGAAAAAC
GGTGAATTTTTCATGTCCCCCAATGACTTTGTCACTCGATACTTGAACATTTTTGGAGAAAGCCAGCCTAATCCAAAGACTGTGGAACTT
TTAAGTGGAGTGGTGGATCAGACCAAAGATGGATTAATATCTTTTCAAGAATTTGTTGCCTTTGAATCTGTCCTGTGTGCCCCTGATGCT
TTGTTTATGGTAGCCTTTCAGCTGTTTGACAAAGCTGGCAAAGGAGAAGTAACTTTTGAGGATGTTAAGCAAGTTTTTGGACAGACCACA
ATTCATCAACATATTCCATTTAACTGGGATTCAGAATTTGTGCAACTACATTTTGGAAAAGAAAGAAAAAGACACCTGACATATGCGGAA
TTTACTCAGTTTTTATTGGAAATACAACTGGAGCACGCAAAGCAAGCCTTTGTGCAACGGGACAATGCTAGGACTGGGAGAGTCACAGCC
ATCGACTTCCGAGACATCATGGTCACCATCCGCCCCCATGTCTTGACTCCTTTTGTAGAAGAATGTCTAGTAGCTGCTGCTGGAGGTACC
ACATCCCATCAAGTTAGTTTCTCCTATTTTAATGGATTTAATTCGCTCCTTAACAACATGGAACTCATTAGAAAGATCTATAGCACTCTG
GCTGGCACCAGGAAAGATGTTGAAGTGACTAAGGAGGAGTTTGTTCTGGCAGCTCAGAAATTTGGTCAGGTTACACCCATGGAAGTTGAC
ATCTTGTTTCAGTTAGCAGATTTATATGAGCCAAGGGGACGTATGACCTTAGCAGACATTGAACGGATTGCTCCTCTGGAAGAGGGAACT
CTGCCCTTTAACTTGGCTGAGGCCCAGAGGCAGCAGAAGGCCTCAGGTGATTCAGCTCGACCAGTTCTTCTACAAGTTGCAGAGTCGGCC
TACAGGTTTGGTCTGGGTTCTGTTGCTGGAGCTGTTGGAGCCACTGCTGTGTATCCTATCGATCTTGTAAAAACTCGAATGCAGAACCAA
CGATCAACTGGCTCTTTTGTGGGAGAACTCATGTATAAAAACAGCTTTGACTGTTTTAAGAAAGTGCTACGCTATGAAGGCTTCTTTGGA
CTGTATAGAGAGACCAAGAAGCGTCAGTGTAAAGTTCTTTTTGAGTACATTCCACAAAATGAGGATGAACTGGAGCTGAAAGTGGGAGAT
ATTATTGATATTAATGAAGAGGTAGAAGAAGGCTGGTGGAGTGGAACCCTGAATAACAAGTTGGGACTGTTTCCCTCAAATTTTGTGAAA
GAATTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACGATTCAGAAACTGTTTTGGCTGGGCCTACTTCACCTATACCTTCT
CTGGGAAATGTGAGTGAAACTGCATCTGGATCAGTTACACAGCCAAAGAAAATTCGAGGAATTGGATTTGGAGACATTTTTAAAGAAGGC
TCTGTGAAACTTCGGACAAGAACATCCAGTAGTGAAACAGAAGAGAAAAAACCAGAAAAGCCCTTAATCCTACAGTCACTGGGACCCAAA
ACTCAGAGTGTGGAGATAACAAAAACAGATACCGAAGGTAAAATTAAAGCTAAAGAATATTGTAGAACATTATTTGCCTATGAAGGTACT
AATGAAGATGAACTTACTTTTAAAGAGGGGGAGATAATCCATTTGATAAGTAAGGAGACTGGAGAAGCTGGCTGGTGGAGGGGCGAACTT
AATGGTAAAGAAGGAGTATTTCCAGACAATTTTGCTGTCCAGATAAATGAACTTGATAAAGACTTTCCAAAACCAAAGAAACCACCACCT
CCTGCTAAGGCTCCAGCTCCAAAGCCTGAACTGATAGCTGCAGAGAAGAAATATTTTTCTTTAAAGCCTGAAGAAAAGGATGAAAAATCA
ACACTGGAACAGAAACCTTCTAAACCAGCAGCTCCACAAGTCCCACCCAAGAAACCTACTCCACCTACCAAAGCCAGTAATTTACTGAGA
TCTTCTGGAACAGTGTACCCAAAGCGACCTGAAAAACCAGTTCCTCCACCACCTCCTATAGCCAAGATTAATGGGGAAGTTTCTAGCATT
TCATCAAAATTTGAAACTGAGCCAGTATCAAAACTAAAGCTAGATTCTGAACAGCTGCCCCTTAGACCAAAATCAGTAGACTTTGATTCA
CTTACAGTAAGGACCTCCAAAGAAACAGATGTTGTAAATTTTGATGACATAGCTTCCTCAGAAAACTTGCTTCATCTCACTGCAAATAGA
CCAAAGATGCCTGGAAGAAGGTTGCCGGGCCGTTTCAATGGTGGACATTCTCCAACTCACAGCCCCGAAAAAATCTTGAAGTTACCAAAA
GAAGAAGACAGTGCCAACCTGAAGCCATCTGAATTAAAAAAAGATACATGCTACTCTCCAAAGCCATCTGTGTACCTTTCAACACCTTCC
AGTGCTTCTAAAGCAAATACAACTGCTTTCCTGACTCCATTAGAAATCAAAGCTAAAGTGGAAACAGATGATGTGAAAAAAAATTCCCTG
GATGAACTTAGAGCCCAGATTATTGAATTGTTGTGCATTGTAGAAGCACTGAAAAAGGATCACGGGAAAGAACTGGAAAAACTGCGAAAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_SLC25A13_ENST00000265631_chr7_95813589_-_CD2AP_ENST00000359314_chr6_47512342_+_5951nt
GGCCAGGAACGCACGCTGCCTGGCCGTATCGCCGCCCCCACCGCCGCCGCCGCCGGGACTAGAAGTGAGCCGCCCGGGTCCCAAACGCCA
GCCAGCCAGTCAGTGGGTCCCGCAGTCGCCCGCAACCGGGGCGAATCATGGCGGCCGCCAAGGTGGCTTTAACCAAGAGAGCAGATCCAG
CTGAGCTTAGAACAATATTTTTGAAGTATGCAAGCATTGAGAAAAACGGTGAATTTTTCATGTCCCCCAATGACTTTGTCACTCGATACT
TGAACATTTTTGGAGAAAGCCAGCCTAATCCAAAGACTGTGGAACTTTTAAGTGGAGTGGTGGATCAGACCAAAGATGGATTAATATCTT
TTCAAGAATTTGTTGCCTTTGAATCTGTCCTGTGTGCCCCTGATGCTTTGTTTATGGTAGCCTTTCAGCTGTTTGACAAAGCTGGCAAAG
GAGAAGTAACTTTTGAGGATGTTAAGCAAGTTTTTGGACAGACCACAATTCATCAACATATTCCATTTAACTGGGATTCAGAATTTGTGC
AACTACATTTTGGAAAAGAAAGAAAAAGACACCTGACATATGCGGAATTTACTCAGTTTTTATTGGAAATACAACTGGAGCACGCAAAGC
AAGCCTTTGTGCAACGGGACAATGCTAGGACTGGGAGAGTCACAGCCATCGACTTCCGAGACATCATGGTCACCATCCGCCCCCATGTCT
TGACTCCTTTTGTAGAAGAATGTCTAGTAGCTGCTGCTGGAGGTACCACATCCCATCAAGTTAGTTTCTCCTATTTTAATGGATTTAATT
CGCTCCTTAACAACATGGAACTCATTAGAAAGATCTATAGCACTCTGGCTGGCACCAGGAAAGATGTTGAAGTGACTAAGGAGGAGTTTG
TTCTGGCAGCTCAGAAATTTGGTCAGGTTACACCCATGGAAGTTGACATCTTGTTTCAGTTAGCAGATTTATATGAGCCAAGGGGACGTA
TGACCTTAGCAGACATTGAACGGATTGCTCCTCTGGAAGAGGGAACTCTGCCCTTTAACTTGGCTGAGGCCCAGAGGCAGAAGGCCTCAG
GTGATTCAGCTCGACCAGTTCTTCTACAAGTTGCAGAGTCGGCCTACAGGTTTGGTCTGGGTTCTGTTGCTGGAGCTGTTGGAGCCACTG
CTGTGTATCCTATCGATCTTGTAAAAACTCGAATGCAGAACCAACGATCAACTGGCTCTTTTGTGGGAGAACTCATGTATAAAAACAGCT
TTGACTGTTTTAAGAAAGTGCTACGCTATGAAGGCTTCTTTGGACTGTATAGAGAGACCAAGAAGCGTCAGTGTAAAGTTCTTTTTGAGT
ACATTCCACAAAATGAGGATGAACTGGAGCTGAAAGTGGGAGATATTATTGATATTAATGAAGAGGTAGAAGAAGGCTGGTGGAGTGGAA
CCCTGAATAACAAGTTGGGACTGTTTCCCTCAAATTTTGTGAAAGAATTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACG
ATTCAGAAACTGTTTTGGCTGGGCCTACTTCACCTATACCTTCTCTGGGAAATGTGAGTGAAACTGCATCTGGATCAGTTACACAGCCAA
AGAAAATTCGAGGAATTGGATTTGGAGACATTTTTAAAGAAGGCTCTGTGAAACTTCGGACAAGAACATCCAGTAGTGAAACAGAAGAGA
AAAAACCAGAAAAGCCCTTAATCCTACAGTCACTGGGACCCAAAACTCAGAGTGTGGAGATAACAAAAACAGATACCGAAGGTAAAATTA
AAGCTAAAGAATATTGTAGAACATTATTTGCCTATGAAGGTACTAATGAAGATGAACTTACTTTTAAAGAGGGGGAGATAATCCATTTGA
TAAGTAAGGAGACTGGAGAAGCTGGCTGGTGGAGGGGCGAACTTAATGGTAAAGAAGGAGTATTTCCAGACAATTTTGCTGTCCAGATAA
ATGAACTTGATAAAGACTTTCCAAAACCAAAGAAACCACCACCTCCTGCTAAGGCTCCAGCTCCAAAGCCTGAACTGATAGCTGCAGAGA
AGAAATATTTTTCTTTAAAGCCTGAAGAAAAGGATGAAAAATCAACACTGGAACAGAAACCTTCTAAACCAGCAGCTCCACAAGTCCCAC
CCAAGAAACCTACTCCACCTACCAAAGCCAGTAATTTACTGAGATCTTCTGGAACAGTGTACCCAAAGCGACCTGAAAAACCAGTTCCTC
CACCACCTCCTATAGCCAAGATTAATGGGGAAGTTTCTAGCATTTCATCAAAATTTGAAACTGAGCCAGTATCAAAACTAAAGCTAGATT
CTGAACAGCTGCCCCTTAGACCAAAATCAGTAGACTTTGATTCACTTACAGTAAGGACCTCCAAAGAAACAGATGTTGTAAATTTTGATG
ACATAGCTTCCTCAGAAAACTTGCTTCATCTCACTGCAAATAGACCAAAGATGCCTGGAAGAAGGTTGCCGGGCCGTTTCAATGGTGGAC
ATTCTCCAACTCACAGCCCCGAAAAAATCTTGAAGTTACCAAAAGAAGAAGACAGTGCCAACCTGAAGCCATCTGAATTAAAAAAAGATA
CATGCTACTCTCCAAAGCCATCTGTGTACCTTTCAACACCTTCCAGTGCTTCTAAAGCAAATACAACTGCTTTCCTGACTCCATTAGAAA
TCAAAGCTAAAGTGGAAACAGATGATGTGAAAAAAAATTCCCTGGATGAACTTAGAGCCCAGATTATTGAATTGTTGTGCATTGTAGAAG
CACTGAAAAAGGATCACGGGAAAGAACTGGAAAAACTGCGAAAAGATTTGGAAGAAGAGAAGACAATGAGAAGTAATCTAGAGATGGAAA
TAGAGAAGCTGAAAAAAGCTGTCCTGTCTTCTTGAGTGGTGTGGACCTGGTGTTCATAATGTTCCAGGGATTCAGAAGCAACGCTATGAA
CTTCAGCTGACTTGTTACTTAAAAATTGTGAATTCTGTTGTTGTGATAAATATGAGCAAATGAAGTGTAATATCTATAGAAAAGTAGAGT
GAGGGTGAATTTATATATATATTTTGTTTTGCCAATATGAAGAAAAAGAGGCCTTATTTCTTAACTGTGCTGGGATTGCAAACACTTTTT
AAAAAATTGTTTGCTTGAAAATACTACTGAATATAAATAAGAATGTGCACAGTAGTTTTTTTATTGAAACTTGTATTATTTTTAAAGAGA
TCTATACTATAAATATGGTGATATATTTACAAGTAATCTGTTAAGATATACTATTTGAGAGGGACAGATTAGCCTTTTAGTAACTATAGT
CACTACTTTTTCCATAATGCATAAGGGATATAAACTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATAT
ATATATTTTTACTTTTATCCTCTTACCGAAGGTTACACTGTTGTGCCTGTTTGTCTGCAATGCTGTTTATATTTTGGGTGATGAAATAGG
AGTTTCCTAGCTATATAAACCAGATTACTCACCCATGCATATAGTAAGAACTAATGAATAATCAAAATAATTTCATCAACTTTTAGAATA
TTTTATGTTGCTTGCACTATAGGAGTCATAAAAGGAACTTAGTTAAAATATGTTGGATTGTTAAACATTTGGGGAAATATGAACTGTATT
TTAAATTTGTTAGGTCTGAAGAATCTAAAACTGTTAATTTAACCCTTAACTTGTGCCTAGAAACTACAGCACATATAAAATATGTAAACA
CCAGCCTGTTGCTGTACTTTTCTGCTTATTTTACAGCCTCAAATATTTCTCATTATCTTGTCACTTAGTTCTTCATGTTTCTCCTTCTGA
CTTTTAATAATGGTAATAGGAAAACAAAACCCAAAGCTTTTCAGAACTTCAGTGTGAGGTTTCCTATTTTGACAAGTTAACTTGTAAATA
CTCAGGTTTTACGATGTATAATTTACCTAATAGACCAAACTAACTCATGGAGATATTTTGAACTATTATTTAGGTACAAACTTTATAAAG
AATGTTAGTATGTCATAAAATATAACATTACAGCTTATTTAAAACCAAATATAGTTGAACATATTTAAAATACATTTTCACAGAATGGAT
GAATTAGTTGTTTCTTCAGAGTTACTTATGAACAGTTGAATGCTTTAAAATGTTCTGTCTGTAGGTAACATCTAAAACACAAGTGGGTTT
ATTTAAATTTTTAAAATTTGAAATTTTTTATTTGCAAAAAATTGTTTTATGCTTTATTATATCGCAAATGAGTGTCAGATTTTTGAGTAC
CAATGATCATGCTTCCATTTTTTTTAGTTTTAAACCACCAAACCAATATTTTTCCTTTAAATTTTAATCTTATAATATAGAAATCTTATG
TAAATGAAATTTTGTCATGTTTCAAATAAAGAGAACTGAAGTAGAAAATAGAAATGCCAGTAAACAACATAATGTTTAATTTACAACTTA
CATTAGGGGTTTGGGGGAATGCTAATTATATATTGAGAATATACATTAGAACTCTTCAAAATGGGCTCTTCTAATGAGGTCACTACTGAA
CAAAATTGTTCCCTCTTCTGTTAAATAGAATAGGTTTAAATGACTAGTCAAATGAATTATTTTCTTCTTGTTAAATAAATTAAATCTTAC
TTTCTTTTAATGACCAACCTTAGGTAAAACAAAAATATTGTAATCCTAGAAATTATCCTCCAGCTTTCTCACCTGAAAATCTATTGAAGT
GATCCCTGGTCATCCTAATAATGGGATGAGGGAAGTTTCCAGCAGATTTCAGGCTGTTCTTAAAGTTTTTGTTGGTCATTTTCTCAATAG
TACATGAAATCAAGATGCTTATGAGCATGGAAATGTATTTAAAGTTTTTGCTTGTGTCCTCCTCAGTCAGAATAGAAAAGTAACTGAAAT
ACTTTTACCTTTCTGTCCTTGATAAAATAGTAAAGAAAACCAAACAAACCCAGGCCTGATGGGAAAAATGATTCCTTTATTCTAGCAACT
TACTTTCTGTTGGTATGGGAAATGTTATTAATTTCTATTACTAAAGTTCATATCACAAAATGATATTTAATAATAACCTTGGGGTAAATC
ATGAATTTTTTTTCTACGTGTGAGTATAAAAGACAAAAGTTGAACAGCATGGAATCTCATTGCCAAATTATTAGTGAATGTATAGTTCAG
GTATTCTTTGAGACACACAGTATCATTAATTTCTGAATTGTATTTCAGTGTTATTTTTTGTTTGTGACCACTAAGCTTCTGTCTTAATAC
AAAGCTGTTACCTTCTACAGAATTTAAGTCTGAAGATGTAAAGAGAGAACAGGCCTTGTGTAACAGAAGATACTCTTTTTTATGCTCCTT
ACTGTGATCACAGAAAAATTAAAAATCCAAGTGCTCTCTAGATTTGTTGATAAACATTTTATGCTTGCATTTAAACTTGAAATGTATGAG
CAGAATGAGACAATCAGTTAAATCAGAAATGAGAAGTATTATAATGTAAAGGCCTTGTTTTGCTGTAGCAATAAAATGACCAAGTGCAAT
GACTTGATTTAATAAAATCATATTTTAAAAGTTGCTGCTATGAATATTTTTGGCTATAAAATTTTACCCTGACTTGCTTTCAATAACTGT
TACGTAATGCAGTTGATGTTGTAACCTAACATTCCAAAAAAAAAATTGAGAGGGGGAATCTCAAAATAGTATATACTTCACTAACTTGTT
TACAGGTGCTGTATTTAAAAGCATGCTTCTCTCTCAAAAAGAAAAATTAAAGGATTTTATTGCCAGTCGTGTCAGTCTTTATTGGTTATT
TTTTGTTAACTTTAGCATTTGTGTATTTCAGAGTATGATGAAAATTATATTACTTCAATTTCCAAATACAAGAATAAATAGTAAACCAAA

>In-frame_SLC25A13_ENST00000416240_chr7_95813589_-_CD2AP_ENST00000359314_chr6_47512342_+_6008nt
AATGGGCGGGCAGCATCCACATGACCCGCGCCGGCGGGAGGGCGTGGGGAGGCAGGCCAGGAACGCACGCTGCCTGGCCGTATCGCCGCC
CCCACCGCCGCCGCCGCCGGGACTAGAAGTGAGCCGCCCGGGTCCCAAACGCCAGCCAGCCAGTCAGTGGGTCCCGCAGTCGCCCGCAAC
CGGGGCGAATCATGGCGGCCGCCAAGGTGGCTTTAACCAAGAGAGCAGATCCAGCTGAGCTTAGAACAATATTTTTGAAGTATGCAAGCA
TTGAGAAAAACGGTGAATTTTTCATGTCCCCCAATGACTTTGTCACTCGATACTTGAACATTTTTGGAGAAAGCCAGCCTAATCCAAAGA
CTGTGGAACTTTTAAGTGGAGTGGTGGATCAGACCAAAGATGGATTAATATCTTTTCAAGAATTTGTTGCCTTTGAATCTGTCCTGTGTG
CCCCTGATGCTTTGTTTATGGTAGCCTTTCAGCTGTTTGACAAAGCTGGCAAAGGAGAAGTAACTTTTGAGGATGTTAAGCAAGTTTTTG
GACAGACCACAATTCATCAACATATTCCATTTAACTGGGATTCAGAATTTGTGCAACTACATTTTGGAAAAGAAAGAAAAAGACACCTGA
CATATGCGGAATTTACTCAGTTTTTATTGGAAATACAACTGGAGCACGCAAAGCAAGCCTTTGTGCAACGGGACAATGCTAGGACTGGGA
GAGTCACAGCCATCGACTTCCGAGACATCATGGTCACCATCCGCCCCCATGTCTTGACTCCTTTTGTAGAAGAATGTCTAGTAGCTGCTG
CTGGAGGTACCACATCCCATCAAGTTAGTTTCTCCTATTTTAATGGATTTAATTCGCTCCTTAACAACATGGAACTCATTAGAAAGATCT
ATAGCACTCTGGCTGGCACCAGGAAAGATGTTGAAGTGACTAAGGAGGAGTTTGTTCTGGCAGCTCAGAAATTTGGTCAGGTTACACCCA
TGGAAGTTGACATCTTGTTTCAGTTAGCAGATTTATATGAGCCAAGGGGACGTATGACCTTAGCAGACATTGAACGGATTGCTCCTCTGG
AAGAGGGAACTCTGCCCTTTAACTTGGCTGAGGCCCAGAGGCAGCAGAAGGCCTCAGGTGATTCAGCTCGACCAGTTCTTCTACAAGTTG
CAGAGTCGGCCTACAGGTTTGGTCTGGGTTCTGTTGCTGGAGCTGTTGGAGCCACTGCTGTGTATCCTATCGATCTTGTAAAAACTCGAA
TGCAGAACCAACGATCAACTGGCTCTTTTGTGGGAGAACTCATGTATAAAAACAGCTTTGACTGTTTTAAGAAAGTGCTACGCTATGAAG
GCTTCTTTGGACTGTATAGAGAGACCAAGAAGCGTCAGTGTAAAGTTCTTTTTGAGTACATTCCACAAAATGAGGATGAACTGGAGCTGA
AAGTGGGAGATATTATTGATATTAATGAAGAGGTAGAAGAAGGCTGGTGGAGTGGAACCCTGAATAACAAGTTGGGACTGTTTCCCTCAA
ATTTTGTGAAAGAATTAGAGGTAACAGATGATGGTGAAACTCATGAAGCCCAGGACGATTCAGAAACTGTTTTGGCTGGGCCTACTTCAC
CTATACCTTCTCTGGGAAATGTGAGTGAAACTGCATCTGGATCAGTTACACAGCCAAAGAAAATTCGAGGAATTGGATTTGGAGACATTT
TTAAAGAAGGCTCTGTGAAACTTCGGACAAGAACATCCAGTAGTGAAACAGAAGAGAAAAAACCAGAAAAGCCCTTAATCCTACAGTCAC
TGGGACCCAAAACTCAGAGTGTGGAGATAACAAAAACAGATACCGAAGGTAAAATTAAAGCTAAAGAATATTGTAGAACATTATTTGCCT
ATGAAGGTACTAATGAAGATGAACTTACTTTTAAAGAGGGGGAGATAATCCATTTGATAAGTAAGGAGACTGGAGAAGCTGGCTGGTGGA
GGGGCGAACTTAATGGTAAAGAAGGAGTATTTCCAGACAATTTTGCTGTCCAGATAAATGAACTTGATAAAGACTTTCCAAAACCAAAGA
AACCACCACCTCCTGCTAAGGCTCCAGCTCCAAAGCCTGAACTGATAGCTGCAGAGAAGAAATATTTTTCTTTAAAGCCTGAAGAAAAGG
ATGAAAAATCAACACTGGAACAGAAACCTTCTAAACCAGCAGCTCCACAAGTCCCACCCAAGAAACCTACTCCACCTACCAAAGCCAGTA
ATTTACTGAGATCTTCTGGAACAGTGTACCCAAAGCGACCTGAAAAACCAGTTCCTCCACCACCTCCTATAGCCAAGATTAATGGGGAAG
TTTCTAGCATTTCATCAAAATTTGAAACTGAGCCAGTATCAAAACTAAAGCTAGATTCTGAACAGCTGCCCCTTAGACCAAAATCAGTAG
ACTTTGATTCACTTACAGTAAGGACCTCCAAAGAAACAGATGTTGTAAATTTTGATGACATAGCTTCCTCAGAAAACTTGCTTCATCTCA
CTGCAAATAGACCAAAGATGCCTGGAAGAAGGTTGCCGGGCCGTTTCAATGGTGGACATTCTCCAACTCACAGCCCCGAAAAAATCTTGA
AGTTACCAAAAGAAGAAGACAGTGCCAACCTGAAGCCATCTGAATTAAAAAAAGATACATGCTACTCTCCAAAGCCATCTGTGTACCTTT
CAACACCTTCCAGTGCTTCTAAAGCAAATACAACTGCTTTCCTGACTCCATTAGAAATCAAAGCTAAAGTGGAAACAGATGATGTGAAAA
AAAATTCCCTGGATGAACTTAGAGCCCAGATTATTGAATTGTTGTGCATTGTAGAAGCACTGAAAAAGGATCACGGGAAAGAACTGGAAA
AACTGCGAAAAGATTTGGAAGAAGAGAAGACAATGAGAAGTAATCTAGAGATGGAAATAGAGAAGCTGAAAAAAGCTGTCCTGTCTTCTT
GAGTGGTGTGGACCTGGTGTTCATAATGTTCCAGGGATTCAGAAGCAACGCTATGAACTTCAGCTGACTTGTTACTTAAAAATTGTGAAT
TCTGTTGTTGTGATAAATATGAGCAAATGAAGTGTAATATCTATAGAAAAGTAGAGTGAGGGTGAATTTATATATATATTTTGTTTTGCC
AATATGAAGAAAAAGAGGCCTTATTTCTTAACTGTGCTGGGATTGCAAACACTTTTTAAAAAATTGTTTGCTTGAAAATACTACTGAATA
TAAATAAGAATGTGCACAGTAGTTTTTTTATTGAAACTTGTATTATTTTTAAAGAGATCTATACTATAAATATGGTGATATATTTACAAG
TAATCTGTTAAGATATACTATTTGAGAGGGACAGATTAGCCTTTTAGTAACTATAGTCACTACTTTTTCCATAATGCATAAGGGATATAA
ACTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATATATATATATATATTTTTACTTTTATCCTCTTACCGAAGGT
TACACTGTTGTGCCTGTTTGTCTGCAATGCTGTTTATATTTTGGGTGATGAAATAGGAGTTTCCTAGCTATATAAACCAGATTACTCACC
CATGCATATAGTAAGAACTAATGAATAATCAAAATAATTTCATCAACTTTTAGAATATTTTATGTTGCTTGCACTATAGGAGTCATAAAA
GGAACTTAGTTAAAATATGTTGGATTGTTAAACATTTGGGGAAATATGAACTGTATTTTAAATTTGTTAGGTCTGAAGAATCTAAAACTG
TTAATTTAACCCTTAACTTGTGCCTAGAAACTACAGCACATATAAAATATGTAAACACCAGCCTGTTGCTGTACTTTTCTGCTTATTTTA
CAGCCTCAAATATTTCTCATTATCTTGTCACTTAGTTCTTCATGTTTCTCCTTCTGACTTTTAATAATGGTAATAGGAAAACAAAACCCA
AAGCTTTTCAGAACTTCAGTGTGAGGTTTCCTATTTTGACAAGTTAACTTGTAAATACTCAGGTTTTACGATGTATAATTTACCTAATAG
ACCAAACTAACTCATGGAGATATTTTGAACTATTATTTAGGTACAAACTTTATAAAGAATGTTAGTATGTCATAAAATATAACATTACAG
CTTATTTAAAACCAAATATAGTTGAACATATTTAAAATACATTTTCACAGAATGGATGAATTAGTTGTTTCTTCAGAGTTACTTATGAAC
AGTTGAATGCTTTAAAATGTTCTGTCTGTAGGTAACATCTAAAACACAAGTGGGTTTATTTAAATTTTTAAAATTTGAAATTTTTTATTT
GCAAAAAATTGTTTTATGCTTTATTATATCGCAAATGAGTGTCAGATTTTTGAGTACCAATGATCATGCTTCCATTTTTTTTAGTTTTAA
ACCACCAAACCAATATTTTTCCTTTAAATTTTAATCTTATAATATAGAAATCTTATGTAAATGAAATTTTGTCATGTTTCAAATAAAGAG
AACTGAAGTAGAAAATAGAAATGCCAGTAAACAACATAATGTTTAATTTACAACTTACATTAGGGGTTTGGGGGAATGCTAATTATATAT
TGAGAATATACATTAGAACTCTTCAAAATGGGCTCTTCTAATGAGGTCACTACTGAACAAAATTGTTCCCTCTTCTGTTAAATAGAATAG
GTTTAAATGACTAGTCAAATGAATTATTTTCTTCTTGTTAAATAAATTAAATCTTACTTTCTTTTAATGACCAACCTTAGGTAAAACAAA
AATATTGTAATCCTAGAAATTATCCTCCAGCTTTCTCACCTGAAAATCTATTGAAGTGATCCCTGGTCATCCTAATAATGGGATGAGGGA
AGTTTCCAGCAGATTTCAGGCTGTTCTTAAAGTTTTTGTTGGTCATTTTCTCAATAGTACATGAAATCAAGATGCTTATGAGCATGGAAA
TGTATTTAAAGTTTTTGCTTGTGTCCTCCTCAGTCAGAATAGAAAAGTAACTGAAATACTTTTACCTTTCTGTCCTTGATAAAATAGTAA
AGAAAACCAAACAAACCCAGGCCTGATGGGAAAAATGATTCCTTTATTCTAGCAACTTACTTTCTGTTGGTATGGGAAATGTTATTAATT
TCTATTACTAAAGTTCATATCACAAAATGATATTTAATAATAACCTTGGGGTAAATCATGAATTTTTTTTCTACGTGTGAGTATAAAAGA
CAAAAGTTGAACAGCATGGAATCTCATTGCCAAATTATTAGTGAATGTATAGTTCAGGTATTCTTTGAGACACACAGTATCATTAATTTC
TGAATTGTATTTCAGTGTTATTTTTTGTTTGTGACCACTAAGCTTCTGTCTTAATACAAAGCTGTTACCTTCTACAGAATTTAAGTCTGA
AGATGTAAAGAGAGAACAGGCCTTGTGTAACAGAAGATACTCTTTTTTATGCTCCTTACTGTGATCACAGAAAAATTAAAAATCCAAGTG
CTCTCTAGATTTGTTGATAAACATTTTATGCTTGCATTTAAACTTGAAATGTATGAGCAGAATGAGACAATCAGTTAAATCAGAAATGAG
AAGTATTATAATGTAAAGGCCTTGTTTTGCTGTAGCAATAAAATGACCAAGTGCAATGACTTGATTTAATAAAATCATATTTTAAAAGTT
GCTGCTATGAATATTTTTGGCTATAAAATTTTACCCTGACTTGCTTTCAATAACTGTTACGTAATGCAGTTGATGTTGTAACCTAACATT
CCAAAAAAAAAATTGAGAGGGGGAATCTCAAAATAGTATATACTTCACTAACTTGTTTACAGGTGCTGTATTTAAAAGCATGCTTCTCTC
TCAAAAAGAAAAATTAAAGGATTTTATTGCCAGTCGTGTCAGTCTTTATTGGTTATTTTTTGTTAACTTTAGCATTTGTGTATTTCAGAG


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FusionGenePPI for SLC25A13_CD2AP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SLC25A13USP50, BRE, BABAM1, SLX1B, UBC, MYC, ICT1, AGO4, SIRT7, MRPL46, ALB, ATF2, GRB2, CLN3, CLN5, ADRB2, FBXO6, PARK2, ASB8, CCDC8, EGFR, AATK, ARAF, IKBKB, ILK, IRAK1, LIMK2, SIK2, PPT1, NTRK1, ELAVL1, IMMT, CRK, XRCC3, NEIL3, SKI, MCM2, NF2, OTUB1, ZNF746, SLC25A12, CYLD, DLST, PDHA1, SOAT1, VDAC1, TRIM25CD2APRAB4A, CBL, CD2, CAPZA1, CD2AP, NPHS2, BCAR1, MVB12A, SH3KBP1, NPHS1, NR4A1, NR2C2, HBP1, HOXC11, KHDRBS1, BLNK, TRA, PDCD6IP, ACTC1, CBLB, CTTN, EGFR, SH3GL2, DNM2, TSG101, INPP5D, CAPZB, CBLC, ARHGAP17, CAPZA2, MORF4L1P2, SH3BP1, GRB2, NRAS, VCAM1, ITGA4, LMNA, PTGES3, UBC, GZMB, LOX, ARHGEF10, BRCC3, CCDC6, ELP2, SPAG9, HNRNPR, HUWE1, MTA2, NR3C1, IKBKAP, KIAA0196, KIAA1033, LARP7, NOLC1, NRBP1, RABEP2, TSC22D1, USP34, WDHD1, FRS3, UBE2I, SLC25A41, STAP1, TAS2R7, ASNS, CSTF2, DPH5, GALE, IMPDH2, MSN, NPLOC4, PFDN2, PPA2, PRDX6, SCPEP1, SEC24C, SEC24D, TTC27, UFD1L, ZYX, NIT1, MED4, RPGRIP1L, KIF23, ATP6AP2, RACGAP1, KIF15, NF2, CDH1, TCP10L, ARHGAP44, MRPL12, DACH2, SETX, UBE2A


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneCD2APchr7:95813589chr6:47512342ENST00000359314+2181_175106640ANLN and localization to the midbody


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SLC25A13_CD2AP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SLC25A13_CD2AP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLC25A13C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneSLC25A13C1853942CITRULLINEMIA, TYPE II, NEONATAL-ONSET1CTD_human;ORPHANET;UNIPROT
HgeneSLC25A13C1863844Adult-onset citrullinemia type 21CTD_human;ORPHANET
TgeneCD2APC0002395Alzheimer's Disease2CTD_human