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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 34028

FusionGeneSummary for SLC12A2_PPP2CA

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC12A2_PPP2CA
Fusion gene ID: 34028
HgeneTgene
Gene symbol

SLC12A2

PPP2CA

Gene ID

6558

5515

Gene namesolute carrier family 12 member 2protein phosphatase 2 catalytic subunit alpha
SynonymsBSC|BSC2|NKCC1|PPP1R141PP2Ac|PP2CA|PP2Calpha|RP-C
Cytomap

5q23.3

5q31.1

Type of geneprotein-codingprotein-coding
Descriptionsolute carrier family 12 member 2basolateral Na-K-Cl symporterbumetanide-sensitive sodium-(potassium)-chloride cotransporter 1protein phosphatase 1, regulatory subunit 141solute carrier family 12 (sodium/potassium/chloride transporter), member 2solutserine/threonine-protein phosphatase 2A catalytic subunit alpha isoformPP2A-alphaprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoformprotein phosphatase 2, catalytic subunit, alpha isozymereplication protein Cserine/threonine protein
Modification date2018052320180523
UniProtAcc

P55011

P67775

Ensembl transtripts involved in fusion geneENST00000262461, ENST00000343225, 
ENST00000507791, 		ENST00000481195, 
ENST00000231504, 
Fusion gene scores* DoF score9 X 6 X 4=2164 X 6 X 3=72
# samples 96
** MAII scorelog2(9/216*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/72*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC12A2 [Title/Abstract] AND PPP2CA [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLC12A2

GO:0015696

ammonium transport

12946942|18032481

HgeneSLC12A2

GO:0030321

transepithelial chloride transport

12946942

HgeneSLC12A2

GO:0070634

transepithelial ammonium transport

18032481


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSTADTCGA-HU-A4GH-01ASLC12A2chr5

127420402

+PPP2CAchr5

133537712

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000262461ENST00000481195SLC12A2chr5

127420402

+PPP2CAchr5

133537712

-
5CDS-intronENST00000262461ENST00000231504SLC12A2chr5

127420402

+PPP2CAchr5

133537712

-
In-frameENST00000343225ENST00000481195SLC12A2chr5

127420402

+PPP2CAchr5

133537712

-
5CDS-intronENST00000343225ENST00000231504SLC12A2chr5

127420402

+PPP2CAchr5

133537712

-
intron-3CDSENST00000507791ENST00000481195SLC12A2chr5

127420402

+PPP2CAchr5

133537712

-
intron-intronENST00000507791ENST00000231504SLC12A2chr5

127420402

+PPP2CAchr5

133537712

-

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FusionProtFeatures for SLC12A2_PPP2CA


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SLC12A2

P55011

PPP2CA

P67775

Electrically silent transporter system. Mediates sodiumand chloride reabsorption. Plays a vital role in the regulation ofionic balance and cell volume. PP2A is the major phosphatase for microtubule-associatedproteins (MAPs). PP2A can modulate the activity of phosphorylase Bkinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2kinase. Cooperates with SGO2 to protect centromeric cohesin fromseparase-mediated cleavage in oocytes specifically during meiosisI (By similarity). Can dephosphorylate SV40 large T antigen andp53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.{ECO:0000250, ECO:0000269|PubMed:10801873,ECO:0000269|PubMed:22613722, ECO:0000269|PubMed:9920888}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127188_1942521213Compositional biasNote=Poly-Gly
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+12790_1222521213Compositional biasNote=Ala-rich
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126188_1942521197Compositional biasNote=Poly-Gly
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+12690_1222521197Compositional biasNote=Ala-rich

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+1271_2852521213Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127307_3182521213Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127342_3662521213Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127388_4102521213Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127432_4352521213Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127457_4862521213Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127508_5202521213Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127542_5912521213Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127613_6542521213Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127676_6802521213Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127700_7242521213Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127746_8992521213Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127921_12122521213Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+1261_2852521197Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126307_3182521197Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126342_3662521197Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126388_4102521197Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126432_4352521197Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126457_4862521197Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126508_5202521197Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126542_5912521197Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126613_6542521197Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126676_6802521197Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126700_7242521197Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126746_8992521197Topological domainExtracellular
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126921_12122521197Topological domainCytoplasmic
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127286_3062521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127319_3412521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127367_3872521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127411_4312521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127436_4562521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127487_5072521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127521_5412521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127592_6122521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127655_6752521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127681_6992521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127725_7452521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000262461+127900_9202521213TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126286_3062521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126319_3412521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126367_3872521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126411_4312521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126436_4562521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126487_5072521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126521_5412521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126592_6122521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126655_6752521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126681_6992521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126725_7452521197TransmembraneHelical
HgeneSLC12A2chr5:127420402chr5:133537712ENST00000343225+126900_9202521197TransmembraneHelical


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FusionGeneSequence for SLC12A2_PPP2CA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SLC12A2_ENST00000262461_chr5_127420402_+_PPP2CA_ENST00000481195_chr5_133537712_-_458aa
MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGGGVRDEGPAAAGDGLGRPLGPTPSQSRFQVDLVSENA
GRAAAAAAAAAAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLS
EGSSLHSGGGGGSGHHQHYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKVRYRERITILRGNHESRQ
ITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGIS
PRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTR

>In-frame_SLC12A2_ENST00000343225_chr5_127420402_+_PPP2CA_ENST00000481195_chr5_133537712_-_458aa
MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGGGVRDEGPAAAGDGLGRPLGPTPSQSRFQVDLVSENA
GRAAAAAAAAAAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLS
EGSSLHSGGGGGSGHHQHYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKVRYRERITILRGNHESRQ
ITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGIS
PRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SLC12A2_ENST00000262461_chr5_127420402_+_PPP2CA_ENST00000481195_chr5_133537712_-_1374nt
ATGGAGCCGCGGCCCACGGCGCCCTCCTCCGGCGCCCCGGGACTGGCCGGGGTCGGGGAGACGCCGTCAGCCGCTGCGCTGGCCGCAGCC
AGGGTGGAACTGCCCGGCACGGCTGTGCCCTCGGTGCCGGAGGATGCTGCGCCCGCGAGCCGGGACGGCGGCGGGGTCCGCGATGAGGGC
CCCGCGGCGGCCGGGGACGGGCTGGGCAGACCCTTGGGGCCCACCCCGAGCCAGAGCCGTTTCCAGGTGGACCTGGTTTCCGAGAACGCC
GGGCGGGCCGCTGCTGCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCTGGTGCTGGGGCGGGGGCCAAGCAGACCCCCGCGGACGGG
GAAGCCAGCGGCGAGAGCGAGCCGGCTAAAGGCAGCGAGGAAGCCAAGGGCCGCTTCCGCGTGAACTTCGTGGACCCAGCTGCCTCCTCG
TCGGCTGAAGACAGCCTGTCAGATGCTGCCGGGGTCGGAGTCGACGGGCCCAACGTGAGCTTCCAGAACGGCGGGGACACGGTGCTGAGC
GAGGGCAGCAGCCTGCACTCCGGCGGCGGCGGCGGCAGTGGGCACCACCAGCACTACTATTATGATACCCACACCAACACCTACTACCTG
CGCACCTTCGGCCACAACACCATGGACGCTGTGCCCAGGATCGATCACTACCGGCACACAGCCGCGCAGCTGGGCGAGAAGCTGCTCCGG
CCTAGCCTGGCGGAGCTCCACGACGAGCTGGAAAAGGTTCGTTACCGTGAACGCATCACCATTCTTCGAGGGAATCATGAGAGCAGACAG
ATCACACAAGTTTATGGTTTCTATGATGAATGTTTAAGAAAATATGGAAATGCAAATGTTTGGAAATATTTTACAGATCTTTTTGACTAT
CTTCCTCTCACTGCCTTGGTGGATGGGCAGATCTTCTGTCTACATGGTGGTCTCTCGCCATCTATAGATACACTGGATCATATCAGAGCA
CTTGATCGCCTACAAGAAGTTCCCCATGAGGGTCCAATGTGTGACTTGCTGTGGTCAGATCCAGATGACCGTGGTGGTTGGGGTATATCT
CCTCGAGGAGCTGGTTACACCTTTGGGCAAGATATTTCTGAGACATTTAATCATGCCAATGGCCTCACGTTGGTGTCTAGAGCTCACCAG
CTAGTGATGGAGGGATATAACTGGTGCCATGACCGGAATGTAGTAACGATTTTCAGTGCTCCAAACTATTGTTATCGTTGTGGTAACCAA
GCTGCAATCATGGAACTTGACGATACTCTAAAATACTCTTTCTTGCAGTTTGACCCAGCACCTCGTAGAGGCGAGCCACATGTTACTCGT

>In-frame_SLC12A2_ENST00000343225_chr5_127420402_+_PPP2CA_ENST00000481195_chr5_133537712_-_1374nt
ATGGAGCCGCGGCCCACGGCGCCCTCCTCCGGCGCCCCGGGACTGGCCGGGGTCGGGGAGACGCCGTCAGCCGCTGCGCTGGCCGCAGCC
AGGGTGGAACTGCCCGGCACGGCTGTGCCCTCGGTGCCGGAGGATGCTGCGCCCGCGAGCCGGGACGGCGGCGGGGTCCGCGATGAGGGC
CCCGCGGCGGCCGGGGACGGGCTGGGCAGACCCTTGGGGCCCACCCCGAGCCAGAGCCGTTTCCAGGTGGACCTGGTTTCCGAGAACGCC
GGGCGGGCCGCTGCTGCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCTGGTGCTGGGGCGGGGGCCAAGCAGACCCCCGCGGACGGG
GAAGCCAGCGGCGAGAGCGAGCCGGCTAAAGGCAGCGAGGAAGCCAAGGGCCGCTTCCGCGTGAACTTCGTGGACCCAGCTGCCTCCTCG
TCGGCTGAAGACAGCCTGTCAGATGCTGCCGGGGTCGGAGTCGACGGGCCCAACGTGAGCTTCCAGAACGGCGGGGACACGGTGCTGAGC
GAGGGCAGCAGCCTGCACTCCGGCGGCGGCGGCGGCAGTGGGCACCACCAGCACTACTATTATGATACCCACACCAACACCTACTACCTG
CGCACCTTCGGCCACAACACCATGGACGCTGTGCCCAGGATCGATCACTACCGGCACACAGCCGCGCAGCTGGGCGAGAAGCTGCTCCGG
CCTAGCCTGGCGGAGCTCCACGACGAGCTGGAAAAGGTTCGTTACCGTGAACGCATCACCATTCTTCGAGGGAATCATGAGAGCAGACAG
ATCACACAAGTTTATGGTTTCTATGATGAATGTTTAAGAAAATATGGAAATGCAAATGTTTGGAAATATTTTACAGATCTTTTTGACTAT
CTTCCTCTCACTGCCTTGGTGGATGGGCAGATCTTCTGTCTACATGGTGGTCTCTCGCCATCTATAGATACACTGGATCATATCAGAGCA
CTTGATCGCCTACAAGAAGTTCCCCATGAGGGTCCAATGTGTGACTTGCTGTGGTCAGATCCAGATGACCGTGGTGGTTGGGGTATATCT
CCTCGAGGAGCTGGTTACACCTTTGGGCAAGATATTTCTGAGACATTTAATCATGCCAATGGCCTCACGTTGGTGTCTAGAGCTCACCAG
CTAGTGATGGAGGGATATAACTGGTGCCATGACCGGAATGTAGTAACGATTTTCAGTGCTCCAAACTATTGTTATCGTTGTGGTAACCAA
GCTGCAATCATGGAACTTGACGATACTCTAAAATACTCTTTCTTGCAGTTTGACCCAGCACCTCGTAGAGGCGAGCCACATGTTACTCGT


* Fusion transcript sequences (Full-length transcript).
>In-frame_SLC12A2_ENST00000262461_chr5_127420402_+_PPP2CA_ENST00000481195_chr5_133537712_-_5001nt
ACACTCGCGCGCTCGCTCGGCTGCCGGTGGCCTCTGTGGCCGTCCAGGCTAGCGGCGGCCCGCAGGCGGCGGGGAGAAAGACTCTCTCAC
CTGGTCTTGCGGCTGTGGCCACCGCCGGCCAGGGGTGTGGAGGGCGTGCTGCCGGAGACGTCCGCCGGGCTCTGCAGTTCCGCCGGGGGT
CGGGCAGCTATGGAGCCGCGGCCCACGGCGCCCTCCTCCGGCGCCCCGGGACTGGCCGGGGTCGGGGAGACGCCGTCAGCCGCTGCGCTG
GCCGCAGCCAGGGTGGAACTGCCCGGCACGGCTGTGCCCTCGGTGCCGGAGGATGCTGCGCCCGCGAGCCGGGACGGCGGCGGGGTCCGC
GATGAGGGCCCCGCGGCGGCCGGGGACGGGCTGGGCAGACCCTTGGGGCCCACCCCGAGCCAGAGCCGTTTCCAGGTGGACCTGGTTTCC
GAGAACGCCGGGCGGGCCGCTGCTGCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCTGGTGCTGGGGCGGGGGCCAAGCAGACCCCC
GCGGACGGGGAAGCCAGCGGCGAGAGCGAGCCGGCTAAAGGCAGCGAGGAAGCCAAGGGCCGCTTCCGCGTGAACTTCGTGGACCCAGCT
GCCTCCTCGTCGGCTGAAGACAGCCTGTCAGATGCTGCCGGGGTCGGAGTCGACGGGCCCAACGTGAGCTTCCAGAACGGCGGGGACACG
GTGCTGAGCGAGGGCAGCAGCCTGCACTCCGGCGGCGGCGGCGGCAGTGGGCACCACCAGCACTACTATTATGATACCCACACCAACACC
TACTACCTGCGCACCTTCGGCCACAACACCATGGACGCTGTGCCCAGGATCGATCACTACCGGCACACAGCCGCGCAGCTGGGCGAGAAG
CTGCTCCGGCCTAGCCTGGCGGAGCTCCACGACGAGCTGGAAAAGGTTCGTTACCGTGAACGCATCACCATTCTTCGAGGGAATCATGAG
AGCAGACAGATCACACAAGTTTATGGTTTCTATGATGAATGTTTAAGAAAATATGGAAATGCAAATGTTTGGAAATATTTTACAGATCTT
TTTGACTATCTTCCTCTCACTGCCTTGGTGGATGGGCAGATCTTCTGTCTACATGGTGGTCTCTCGCCATCTATAGATACACTGGATCAT
ATCAGAGCACTTGATCGCCTACAAGAAGTTCCCCATGAGGGTCCAATGTGTGACTTGCTGTGGTCAGATCCAGATGACCGTGGTGGTTGG
GGTATATCTCCTCGAGGAGCTGGTTACACCTTTGGGCAAGATATTTCTGAGACATTTAATCATGCCAATGGCCTCACGTTGGTGTCTAGA
GCTCACCAGCTAGTGATGGAGGGATATAACTGGTGCCATGACCGGAATGTAGTAACGATTTTCAGTGCTCCAAACTATTGTTATCGTTGT
GGTAACCAAGCTGCAATCATGGAACTTGACGATACTCTAAAATACTCTTTCTTGCAGTTTGACCCAGCACCTCGTAGAGGCGAGCCACAT
GTTACTCGTCGTACCCCAGACTACTTCCTGTAATGAAATTTTAAACTTGTACAGTATTGCCATGAACCATATATCGACCTAATGGAAATG
GGAAGAGCAACAGTAACTCCAAAGTGTCAGAAAATAGTTAACATTCAAAAAACTTGTTTTCACATGGACCAAAAGATGTGCCATATAAAA
ATACAAAGCCTCTTGTCATCAACAGCCGTGACCACTTTAGAATGAACCAGTTCATTGCATGCTGAAGCGACATTGTTGGTCAAGAAACCA
GTTTCTGGCATAGCGCTATTTGTAGTTACTTTTGCTTTCTCTGAGAGACTGCAGATAATAAGATGTAAACATTAACACCTCGTGAATACA
ATTTAACTTCCATTTAGCTATAGCTTTACTCAGCATGACTGTAGATAAGGATAGCAGCAAACAATCATTGGAGCTTAATGAACATTTTTA
AAAATAATTACCAAGGCCTCCCTTCTACTTGTGAGTTTTGAAATTGTTCTTTTTATTTTCAGGGATACCGTTTAATTTAATTATATGATT
TGTCTGCACTCAGTTTATTCCCTACTCAAATCTCAGCCCCATGTTGTTCTTTGTTATTGTCAGAACCTGGTGAGTTGTTTTGAACAGAAC
TGTTTTTTCCCCTTCCTGTAAGACGATGTGACTGCACAAGAGCACTGCAGTGTTTTTCATAATAAACTTGTGAACTAAGAACTGAGAAGG
TCAAATTTTAATTGTATCAATGGGCAAGACTGGTGCTGTTTATTAAAAAAGTTAAATCAATTGAGTAAATTTTAGAATTTGTAGACTTGT
AGGTAAAATAAAAATCAAGGGCACTACATAACCTCTCTGGTAACTCCTTGACATTCTTCAGATTAACTTCAGGATTTATTTGTATTTCAC
ATATTACAATTTGTCACATTGTTGGTGTGCACTTTGTGGGTTCTTCCTGCATATTAACTTGTTTGTAAGAAAGGAAATCTGTGCTGCTTC
AGTAAGACTTAATTGTAAAACCATATAACTTGAGATTTAAGTCTTTGGGTTTTGTTTTAATAAAACAGCATGTTTTCAGGTAGAGCTTAA
ACTAAATGATGTGTTTACTTAGTGCAGTTTCTGGTTATGAATATTATATTGCTATGTGTATATTATATGGACTCTTTAAAATGATTGACA
GATTGGCAAATTCTTAAATCTTTGTACATTGTTGAGTCATATGTTCTTAGAGTTAAATTTGTCTCAGATAAGAAAGTGTTAAAGCATTAG
CCTGTGTCAAGTTCTTTGAGTGATACTAGTGAAACCAAATAGAAAACTATTGTTGGATCATGATTTAGTCTTATGTACATTCACCCGAAG
ACAAAAATGGTACTTAAAGTGGCAGTGTTCAACATTTAATGAGTTTTTCCCCTTTTATCCTTCGAATAGGATTAGATGTTTAAAAAAAAG
TTCTTCTGTGGGAACTAATATTTGATATTTTAACCTACCAGAGTAAACAGGAACACTTAATCATACTTGTGAGTGTAGTAAATAAAAGTT
TTCTTGCTTTGTGCTGTGTTGAATCTGGAACCAACAGGGAAGTTATAGCATATCCCCTTTCTAAAATGCTTGAGGAACACATACATACCG
AATGTCTTTTCTGATCTAATTGATAGTATTTTTAGTGGCTTGTGGAGTTAATTTTCCAAAGCAAAAGGCCATTAGGGTTTCTACATTTCA
TTTCATTTCATTCTTTTCTTTCACAAGAAATACATTCTCTGTGTGTCTTTTTGTTGCTCTGTCACTCTATGCCCTTTCTCTCCGACTGAA
CAAATAGCTTATCCATGTGCAGTGGTTTTAATACCCAAACAATCTAGACACCAAGCAGCTATTTTTTCCGGTCCTGTGATATCAGAATTG
ACCAAGGAATACGTATATTGTAATTGACACGTGGTGGTATCTTCCAGGTACAAATTCTCTAAATTTTGTGGTTAGCAGAATGGGACTTGT
GATAAGAATAGCTTGGTTTTAGCATAACTAGGGTTTAAAATAATTGTTTAATTATAGAGACTGACCGGGCTTTGGCCATCTAAACTGGAA
AGTGTTAGTACCCTACCTTCTTTTGAAAATGGCTATGGTAAGGAAAATGTGTTAGTAAATTATGTATTTTCTTGAAAAATACATAATTAT
GGTTGGATGGGAATCACTAAGTTGGGTGTTAACTGATGTCTCAATTAGTAACATTAGGATTTTCATTAATAAACCTAAAAAGCTTTCCCT
AAGAACAGGCCTGGCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACCAGGGTGGGTGGATCCCTTGAGGTCAGGAGTTGAAG
AGCAGCCTGGCCAACATGGCAAAACCCCATCTCTACAAAAAATATGAAAATCAGCCGGGCTTGGTGGCATACCATAGTCCCAGCTACTTG
GGAGGCTGAGGTGAGAGGATCGCCTGAGCCCAGGAGATGGAGGTTGCAGTGGGCTGAGATTGTGCCACTGTACTCCAGTCTGGGTGACAG
AGCCAGACCCTGTCTCAAAAATAAAGAGGATTCTGAGTTTGTATAGTGAGGGCTTGCAGAAATTTTGAAACTTATTTTGTAAGTTTACAA
TGAATTTGTACATGATGTGCTCATGTCTTGGGTTGAGTATCCTAGACATGATTTTTTCATTTGCTGCATATTAAACATTTGTTGGTTGTA
GTCGGTATTTCTTAAATAGAAGTTTGTCAATATTAGATTAGTTTCAAGAAGGACTTAGCTCAGGAAAAGGATAGTTATTTCTGTGGTTCT
CAGCTTTGATGCCTACAGAGATTCTGATTTAAATTGCTGGAGGAGGGCCCAGGCATACATTTTTTAAGTTTCCCAAGTGATTCTAATTTA
CATCTAGGGTTAAAAACAGCCAGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTGGGGAGGCCGGGGTGGGTGGATCACCTGATGTCA
GGAGATCGAGACCAGCCTGGCCAGCGTGGTGAAACCCCATCTCTATTAAAAATACAAAACTGACCGGTGTGGTGGCAGGAGCCTGTAATC
CCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACTCAGGAGGAGGAGGTTACAGTGAGCCCAGATCGTGCCATTGCACTCCAGC
CTGGGCAAAAAGAGCAAAACTCCATCTCAAAAAACAAAAACACCTCACTGCTGTTTCCTAAGTACATACTTAAGAAAATTGGGATACATG
GTGGTGGTTCATGGATGTTGATAAGGAATTAAAATGTACCGTGCGACTCTCTGTTTCAGTGGTGACTTTTACCTGTTTAGTATAAATATT
CCTTTGCTTCCAACCATAAATGTGTTCTTAGAAATGGGCCTATAGTTTAGTAACCTATAGTTTGGTAATAGGCTTGTTTGTTTTCAGATG

>In-frame_SLC12A2_ENST00000343225_chr5_127420402_+_PPP2CA_ENST00000481195_chr5_133537712_-_4919nt
TCTCTCACCTGGTCTTGCGGCTGTGGCCACCGCCGGCCAGGGGTGTGGAGGGCGTGCTGCCGGAGACGTCCGCCGGGCTCTGCAGTTCCG
CCGGGGGTCGGGCAGCTATGGAGCCGCGGCCCACGGCGCCCTCCTCCGGCGCCCCGGGACTGGCCGGGGTCGGGGAGACGCCGTCAGCCG
CTGCGCTGGCCGCAGCCAGGGTGGAACTGCCCGGCACGGCTGTGCCCTCGGTGCCGGAGGATGCTGCGCCCGCGAGCCGGGACGGCGGCG
GGGTCCGCGATGAGGGCCCCGCGGCGGCCGGGGACGGGCTGGGCAGACCCTTGGGGCCCACCCCGAGCCAGAGCCGTTTCCAGGTGGACC
TGGTTTCCGAGAACGCCGGGCGGGCCGCTGCTGCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCTGGTGCTGGGGCGGGGGCCAAGC
AGACCCCCGCGGACGGGGAAGCCAGCGGCGAGAGCGAGCCGGCTAAAGGCAGCGAGGAAGCCAAGGGCCGCTTCCGCGTGAACTTCGTGG
ACCCAGCTGCCTCCTCGTCGGCTGAAGACAGCCTGTCAGATGCTGCCGGGGTCGGAGTCGACGGGCCCAACGTGAGCTTCCAGAACGGCG
GGGACACGGTGCTGAGCGAGGGCAGCAGCCTGCACTCCGGCGGCGGCGGCGGCAGTGGGCACCACCAGCACTACTATTATGATACCCACA
CCAACACCTACTACCTGCGCACCTTCGGCCACAACACCATGGACGCTGTGCCCAGGATCGATCACTACCGGCACACAGCCGCGCAGCTGG
GCGAGAAGCTGCTCCGGCCTAGCCTGGCGGAGCTCCACGACGAGCTGGAAAAGGTTCGTTACCGTGAACGCATCACCATTCTTCGAGGGA
ATCATGAGAGCAGACAGATCACACAAGTTTATGGTTTCTATGATGAATGTTTAAGAAAATATGGAAATGCAAATGTTTGGAAATATTTTA
CAGATCTTTTTGACTATCTTCCTCTCACTGCCTTGGTGGATGGGCAGATCTTCTGTCTACATGGTGGTCTCTCGCCATCTATAGATACAC
TGGATCATATCAGAGCACTTGATCGCCTACAAGAAGTTCCCCATGAGGGTCCAATGTGTGACTTGCTGTGGTCAGATCCAGATGACCGTG
GTGGTTGGGGTATATCTCCTCGAGGAGCTGGTTACACCTTTGGGCAAGATATTTCTGAGACATTTAATCATGCCAATGGCCTCACGTTGG
TGTCTAGAGCTCACCAGCTAGTGATGGAGGGATATAACTGGTGCCATGACCGGAATGTAGTAACGATTTTCAGTGCTCCAAACTATTGTT
ATCGTTGTGGTAACCAAGCTGCAATCATGGAACTTGACGATACTCTAAAATACTCTTTCTTGCAGTTTGACCCAGCACCTCGTAGAGGCG
AGCCACATGTTACTCGTCGTACCCCAGACTACTTCCTGTAATGAAATTTTAAACTTGTACAGTATTGCCATGAACCATATATCGACCTAA
TGGAAATGGGAAGAGCAACAGTAACTCCAAAGTGTCAGAAAATAGTTAACATTCAAAAAACTTGTTTTCACATGGACCAAAAGATGTGCC
ATATAAAAATACAAAGCCTCTTGTCATCAACAGCCGTGACCACTTTAGAATGAACCAGTTCATTGCATGCTGAAGCGACATTGTTGGTCA
AGAAACCAGTTTCTGGCATAGCGCTATTTGTAGTTACTTTTGCTTTCTCTGAGAGACTGCAGATAATAAGATGTAAACATTAACACCTCG
TGAATACAATTTAACTTCCATTTAGCTATAGCTTTACTCAGCATGACTGTAGATAAGGATAGCAGCAAACAATCATTGGAGCTTAATGAA
CATTTTTAAAAATAATTACCAAGGCCTCCCTTCTACTTGTGAGTTTTGAAATTGTTCTTTTTATTTTCAGGGATACCGTTTAATTTAATT
ATATGATTTGTCTGCACTCAGTTTATTCCCTACTCAAATCTCAGCCCCATGTTGTTCTTTGTTATTGTCAGAACCTGGTGAGTTGTTTTG
AACAGAACTGTTTTTTCCCCTTCCTGTAAGACGATGTGACTGCACAAGAGCACTGCAGTGTTTTTCATAATAAACTTGTGAACTAAGAAC
TGAGAAGGTCAAATTTTAATTGTATCAATGGGCAAGACTGGTGCTGTTTATTAAAAAAGTTAAATCAATTGAGTAAATTTTAGAATTTGT
AGACTTGTAGGTAAAATAAAAATCAAGGGCACTACATAACCTCTCTGGTAACTCCTTGACATTCTTCAGATTAACTTCAGGATTTATTTG
TATTTCACATATTACAATTTGTCACATTGTTGGTGTGCACTTTGTGGGTTCTTCCTGCATATTAACTTGTTTGTAAGAAAGGAAATCTGT
GCTGCTTCAGTAAGACTTAATTGTAAAACCATATAACTTGAGATTTAAGTCTTTGGGTTTTGTTTTAATAAAACAGCATGTTTTCAGGTA
GAGCTTAAACTAAATGATGTGTTTACTTAGTGCAGTTTCTGGTTATGAATATTATATTGCTATGTGTATATTATATGGACTCTTTAAAAT
GATTGACAGATTGGCAAATTCTTAAATCTTTGTACATTGTTGAGTCATATGTTCTTAGAGTTAAATTTGTCTCAGATAAGAAAGTGTTAA
AGCATTAGCCTGTGTCAAGTTCTTTGAGTGATACTAGTGAAACCAAATAGAAAACTATTGTTGGATCATGATTTAGTCTTATGTACATTC
ACCCGAAGACAAAAATGGTACTTAAAGTGGCAGTGTTCAACATTTAATGAGTTTTTCCCCTTTTATCCTTCGAATAGGATTAGATGTTTA
AAAAAAAGTTCTTCTGTGGGAACTAATATTTGATATTTTAACCTACCAGAGTAAACAGGAACACTTAATCATACTTGTGAGTGTAGTAAA
TAAAAGTTTTCTTGCTTTGTGCTGTGTTGAATCTGGAACCAACAGGGAAGTTATAGCATATCCCCTTTCTAAAATGCTTGAGGAACACAT
ACATACCGAATGTCTTTTCTGATCTAATTGATAGTATTTTTAGTGGCTTGTGGAGTTAATTTTCCAAAGCAAAAGGCCATTAGGGTTTCT
ACATTTCATTTCATTTCATTCTTTTCTTTCACAAGAAATACATTCTCTGTGTGTCTTTTTGTTGCTCTGTCACTCTATGCCCTTTCTCTC
CGACTGAACAAATAGCTTATCCATGTGCAGTGGTTTTAATACCCAAACAATCTAGACACCAAGCAGCTATTTTTTCCGGTCCTGTGATAT
CAGAATTGACCAAGGAATACGTATATTGTAATTGACACGTGGTGGTATCTTCCAGGTACAAATTCTCTAAATTTTGTGGTTAGCAGAATG
GGACTTGTGATAAGAATAGCTTGGTTTTAGCATAACTAGGGTTTAAAATAATTGTTTAATTATAGAGACTGACCGGGCTTTGGCCATCTA
AACTGGAAAGTGTTAGTACCCTACCTTCTTTTGAAAATGGCTATGGTAAGGAAAATGTGTTAGTAAATTATGTATTTTCTTGAAAAATAC
ATAATTATGGTTGGATGGGAATCACTAAGTTGGGTGTTAACTGATGTCTCAATTAGTAACATTAGGATTTTCATTAATAAACCTAAAAAG
CTTTCCCTAAGAACAGGCCTGGCACAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGACCAGGGTGGGTGGATCCCTTGAGGTCAGG
AGTTGAAGAGCAGCCTGGCCAACATGGCAAAACCCCATCTCTACAAAAAATATGAAAATCAGCCGGGCTTGGTGGCATACCATAGTCCCA
GCTACTTGGGAGGCTGAGGTGAGAGGATCGCCTGAGCCCAGGAGATGGAGGTTGCAGTGGGCTGAGATTGTGCCACTGTACTCCAGTCTG
GGTGACAGAGCCAGACCCTGTCTCAAAAATAAAGAGGATTCTGAGTTTGTATAGTGAGGGCTTGCAGAAATTTTGAAACTTATTTTGTAA
GTTTACAATGAATTTGTACATGATGTGCTCATGTCTTGGGTTGAGTATCCTAGACATGATTTTTTCATTTGCTGCATATTAAACATTTGT
TGGTTGTAGTCGGTATTTCTTAAATAGAAGTTTGTCAATATTAGATTAGTTTCAAGAAGGACTTAGCTCAGGAAAAGGATAGTTATTTCT
GTGGTTCTCAGCTTTGATGCCTACAGAGATTCTGATTTAAATTGCTGGAGGAGGGCCCAGGCATACATTTTTTAAGTTTCCCAAGTGATT
CTAATTTACATCTAGGGTTAAAAACAGCCAGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTGGGGAGGCCGGGGTGGGTGGATCACC
TGATGTCAGGAGATCGAGACCAGCCTGGCCAGCGTGGTGAAACCCCATCTCTATTAAAAATACAAAACTGACCGGTGTGGTGGCAGGAGC
CTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACTCAGGAGGAGGAGGTTACAGTGAGCCCAGATCGTGCCATTGC
ACTCCAGCCTGGGCAAAAAGAGCAAAACTCCATCTCAAAAAACAAAAACACCTCACTGCTGTTTCCTAAGTACATACTTAAGAAAATTGG
GATACATGGTGGTGGTTCATGGATGTTGATAAGGAATTAAAATGTACCGTGCGACTCTCTGTTTCAGTGGTGACTTTTACCTGTTTAGTA
TAAATATTCCTTTGCTTCCAACCATAAATGTGTTCTTAGAAATGGGCCTATAGTTTAGTAACCTATAGTTTGGTAATAGGCTTGTTTGTT


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FusionGenePPI for SLC12A2_PPP2CA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SLC12A2STK39, MAPK14, SLC12A2, SEC13, COMMD1, ATP4A, EGFR, CUL7, CCDC8, ILK, LGALS3, LGALS8, MCOLN3, LGALS9, LGALS9C, FAM189A2, ZACN, NTRK1, GNG12, TCTN3, TMEM17, TMEM216, AK1, CDKN2AIP, CDH1, CTDSPL, PTGIR, HTR3A, TMED6PPP2CATRIP13, TBCD, ARL2, TLX1, ISYNA1, MRPS26, PTN, CSNK1A1, PPM1B, CDK2, CDK6, ETF1, RELA, CCNG2, PPP2R5C, PXN, PPP2R3B, PPP2R3A, PPP2R2A, BEST1, CTTNBP2, CTTNBP2NL, STRIP1, MOB4, PDCD10, PPP2R1A, STRN, STRN3, PPP2R5D, PPP2R1B, STRN4, PPP2R2D, PPME1, PPP2R5E, PPFIA1, IGBP1, CCT2, CCT8, CCT3, TCP1, CCT5, CCT6A, CCT7, PPFIA3, PPP2R5A, CCT4, PPFIA2, FGFR1OP, PPP2R5B, STK26, SIKE1, STK24, STK25, TRAF3IP3, PPP2R2C, PRKCD, BCL2, SGK1, SPRY2, PMS2, RBL2, HDAC7, HDAC4, HDAC5, MID1, INTS1, INTS6, PRKDC, TERF1, IRAK1, PRR14L, SGOL1, PRR14, TUBA8, ANKLE2, CEP350, SLMAP, KPNB1, PPP2R2B, PPP2R4, FGFR1OP2, PRKAA1, RALA, AXIN1, MYC, MAPK3, AKT1, CHEK2, TWIST1, PABPC1, CUL3, CUL5, CUL1, MAP3K3, CHUK, IKBKB, IKBKG, VCP, CAV1, PSMC6, NUBP2, CLNS1A, PIN1, DDTL, PIR, PSMD1, SOD1, PSMD3, AURKB, BRCA1, ECT2, MDC1, PAXIP1, CBX5, NOTCH1, KLHL15, SMURF1, VCAM1, FN1, ITGA4, CFTR, RAF1, CTDP1, ID1, NPM1, POLA1, BAG3, CDKN2C, MYH9, XRN1, NRD1, AHCYL1, ARPC4, HNRNPH1, NIF3L1, PFDN1, SSB, TNPO1, TNPO3, RPA3, RPA2, RPA1, ZNF346, HTT, ESPL1, ZFP36, SETBP1, VAC14, EP300, DAPK1, UNC5B, PYGM, CSNK2B, DEC1, RORC, FOXS1, LCMT1, SERTAD4, GRN, SGOL2, KNG1, ZNF114, FOXD4L6, LACC1, SIK2, CAMK1, RPS6KB2, TIPRL, UNK, FNBP1, PPAT, PPP2CB, NTRK1, RAC1, PIM1, AHI1, FECH, NPTX1, PCM1, PPP4R1, PPP4C, RP9, CCDC6, CEP131, PKN3, ATP6V1D, CPSF3L, INTS10, INTS9, INTS12, STRIP2, INTS2, INTS5, INTS4, USP7, ESR1, CDC20, CDC27, NOSIP, ESRRB, CARD11, BCL10, AMBRA1, KISS1R, AR, DUSP19, ARHGEF2, ENSA, FAM122A, FAM122B, FBXL16, TBC1D4, TTC33, UNG, WDR61, PTPDC1, FOXD4, TBCCD1, CDCA4, NCAPD3, FAM19A3, ZNF331, RFWD2, LRRC56, WNT7A, ZNF550, ZNF517, EEF1A1, ZNF785, ZFC3H1, ZNF764, TINAG, KLHDC8A, WDR86, PAK1, VHL, AKT3, AKT2, BRCA2, TRIM25, CCND2, CEBPA, URI1, TRIM28


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SLC12A2_PPP2CA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneSLC12A2P55011DB00887BumetanideSolute carrier family 12 member 2small moleculeapproved
HgeneSLC12A2P55011DB01325QuinethazoneSolute carrier family 12 member 2small moleculeapproved
HgeneSLC12A2P55011DB00761Potassium ChlorideSolute carrier family 12 member 2small moleculeapproved|withdrawn

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RelatedDiseases for SLC12A2_PPP2CA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLC12A2C0036341Schizophrenia4PSYGENET
HgeneSLC12A2C0007222Cardiovascular Diseases1CTD_human
HgeneSLC12A2C0014544Epilepsy1CTD_human
HgeneSLC12A2C0014556Epilepsy, Temporal Lobe1CTD_human
HgeneSLC12A2C0020538Hypertensive disease1CTD_human
HgeneSLC12A2C0024667Animal Mammary Neoplasms1CTD_human
HgeneSLC12A2C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneSLC12A2C0026650Movement Disorders1CTD_human
HgeneSLC12A2C0033578Prostatic Neoplasms1CTD_human
HgeneSLC12A2C0033975Psychotic Disorders1PSYGENET
HgeneSLC12A2C0271650Impaired glucose tolerance1CTD_human
TgenePPP2CAC0004096Asthma1CTD_human
TgenePPP2CAC0018799Heart Diseases1CTD_human
TgenePPP2CAC0151744Myocardial Ischemia1CTD_human