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Fusion gene ID: 34011 |
FusionGeneSummary for SLBP_LETM1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLBP_LETM1 | Fusion gene ID: 34011 | Hgene | Tgene | Gene symbol | SLBP | LETM1 | Gene ID | 7884 | 3954 |
| Gene name | stem-loop binding protein | leucine zipper and EF-hand containing transmembrane protein 1 | |
| Synonyms | HBP | SLC55A1 | |
| Cytomap | 4p16.3 | 4p16.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | histone RNA hairpin-binding proteinhairpin binding protein, histonehistone binding proteinhistone stem-loop binding proteinstem-loop (histone) binding protein | mitochondrial proton/calcium exchanger proteinLETM1 and EF-hand domain-containing protein 1, mitochondrialMdm38 homologleucine zipper-EF-hand containing transmembrane protein 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q14493 | O95202 | |
| Ensembl transtripts involved in fusion gene | ENST00000429429, ENST00000489418, ENST00000318386, ENST00000488267, | ENST00000302787, ENST00000512189, | |
| Fusion gene scores | * DoF score | 3 X 3 X 4=36 | 3 X 3 X 3=27 |
| # samples | 4 | 4 | |
| ** MAII score | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/27*10)=0.567040592723894 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SLBP [Title/Abstract] AND LETM1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SLBP | GO:0051028 | mRNA transport | 19155325 |
| Tgene | LETM1 | GO:0006851 | mitochondrial calcium ion transmembrane transport | 19797662 |
| Tgene | LETM1 | GO:0051560 | mitochondrial calcium ion homeostasis | 19797662 |
| Tgene | LETM1 | GO:0099093 | calcium export from the mitochondrion | 19797662 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | HNSC | TCGA-CR-7370-01A | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| TCGA | RV | LUSC | TCGA-LA-A7SW-01A | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000429429 | ENST00000302787 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| 5CDS-intron | ENST00000429429 | ENST00000512189 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| In-frame | ENST00000489418 | ENST00000302787 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| 5CDS-intron | ENST00000489418 | ENST00000512189 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| In-frame | ENST00000318386 | ENST00000302787 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| 5CDS-intron | ENST00000318386 | ENST00000512189 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| In-frame | ENST00000488267 | ENST00000302787 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| 5CDS-intron | ENST00000488267 | ENST00000512189 | SLBP | chr4 | 1696501 | - | LETM1 | chr4 | 1827410 | - |
| intron-3CDS | ENST00000429429 | ENST00000302787 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| intron-intron | ENST00000429429 | ENST00000512189 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| In-frame | ENST00000489418 | ENST00000302787 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| 5CDS-intron | ENST00000489418 | ENST00000512189 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| In-frame | ENST00000318386 | ENST00000302787 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| 5CDS-intron | ENST00000318386 | ENST00000512189 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| In-frame | ENST00000488267 | ENST00000302787 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
| 5CDS-intron | ENST00000488267 | ENST00000512189 | SLBP | chr4 | 1713601 | - | LETM1 | chr4 | 1817529 | - |
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FusionProtFeatures for SLBP_LETM1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLBP | LETM1 |
| RNA-binding protein involved in the histone pre-mRNAprocessing. Binds the stem-loop structure of replication-dependenthistone pre-mRNAs and contributes to efficient 3'-end processingby stabilizing the complex between histone pre-mRNA and U7 smallnuclear ribonucleoprotein (snRNP), via the histone downstreamelement (HDE). Plays an important role in targeting mature histonemRNA from the nucleus to the cytoplasm and to the translationmachinery. Stabilizes mature histone mRNA and could be involved incell-cycle regulation of histone gene expression. Involved in themechanism by which growing oocytes accumulate histone proteinsthat support early embryogenesis. Binds to the 5' side of thestem-loop structure of histone pre-mRNAs.{ECO:0000269|PubMed:12588979, ECO:0000269|PubMed:19155325}. | Mitochondrial proton/calcium antiporter that mediatesproton-dependent calcium efflux from mitochondrion(PubMed:19797662). Crucial for the maintenance of mitochondrialtubular networks and for the assembly of the supercomplexes of therespiratory chain (PubMed:18628306). Required for the maintenanceof the tubular shape and cristae organization (PubMed:18628306).In contrast to SLC8B1/NCLX, does not constitute the major factorfor mitochondrial calcium extrusion (PubMed:24898248).{ECO:0000269|PubMed:18628306, ECO:0000269|PubMed:19797662,ECO:0000269|PubMed:24898248}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SLBP | chr4:1696501 | chr4:1827410 | ENST00000489418 | - | 7 | 8 | 129_198 | 232 | 271 | Region | Note=RNA-binding |
| Tgene | >LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 676_688 | 360 | 740 | Calcium binding | Ontology_term=ECO:0000255 |
| Tgene | >LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 462_490 | 360 | 740 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 537_627 | 360 | 740 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 708_739 | 360 | 740 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 663_698 | 360 | 740 | Domain | EF-hand |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SLBP | chr4:1696501 | chr4:1827410 | ENST00000429429 | - | 6 | 7 | 129_198 | 193 | 232 | Region | Note=RNA-binding |
| Tgene | LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 115_136 | 360 | 740 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 18_21 | 360 | 740 | Compositional bias | Note=Poly-Pro |
| Tgene | LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 252_537 | 360 | 740 | Domain | Letm1 RBD |
| Tgene | LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 116_208 | 360 | 740 | Topological domain | Mitochondrial intermembrane |
| Tgene | LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 230_739 | 360 | 740 | Topological domain | Mitochondrial matrix |
| Tgene | LETM1 | chr4:1696501 | chr4:1827410 | ENST00000302787 | - | 5 | 14 | 209_229 | 360 | 740 | Transmembrane | Helical |
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FusionGeneSequence for SLBP_LETM1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SLBP_ENST00000429429_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_573aa MACRPRSPPRHQSRCDGDASFTTPEGPKPRSRCSDWASAVEEDEMRTRVNKEMARYKRKLLINDFGRERKSSSGSSDSKESMSTVPADFE TDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAE SSSEPQTSSQDDFLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTL QTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRSEVAKDFEPERVVAAPQRPGTEPQPEMPDTVLQSETLKD TAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIG QIDGLISQLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVKHIPESKLTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHISTSQV >In-frame_SLBP_ENST00000489418_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_612aa MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPESFTTPEGPKPRSRCSDWASAVEEDEMRTRVNK EMARYKRKLLINDFGRERKSSSGSSDSKESMSTVPADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSR RSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAESSSEPQTSSQDDFLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQL KQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKR SEVAKDFEPERVVAAPQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQD YSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVKHIPESKL >In-frame_SLBP_ENST00000318386_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_619aa MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPESFTTPEGPKPRSRCSDWASAVEEDEMRTRVNK EMASNIYFALRYKRKLLINDFGRERKSSSGSSDSKESMSTVPADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPN KFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDLESAESSSEPQTSSQDDFLIAEEGVDSLNVKELQAACRARGMRALGVTE DRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHR EKELQKRSEVAKDFEPERVVAAPQRPGTEPQPEMPDTVLQSETLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELEL LKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVK >In-frame_SLBP_ENST00000488267_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_577aa MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPERYKRKLLINDFGRERKSSSGSSDSKESMSTVP ADFETDESVLMRRQKQINYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWKVALHFWDPPAEEGCDLQEIHPVDL ESAESSSEPQTSSQDDFLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIPTSLLILSRAMYLPDTLSPADQL KSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQEEAAIQQEHREKELQKRSEVAKDFEPERVVAAPQRPGTEPQPEMPDTVLQSE TLKDTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQ QMIGQIDGLISQLEMDQQAGKLAPANGMPTGENVISVAELINAMKQVKHIPESKLTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHIS >In-frame_SLBP_ENST00000489418_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_155aa MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPERENVISVAELINAMKQVKHIPESKLTSLAAAL >In-frame_SLBP_ENST00000318386_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_155aa MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPERENVISVAELINAMKQVKHIPESKLTSLAAAL >In-frame_SLBP_ENST00000488267_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_155aa MACRPRSPPRHQSRCDGDASPPSPARWSLGRKRRADGRRWRPEDAEEAEHRGAERRPERENVISVAELINAMKQVKHIPESKLTSLAAAL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SLBP_ENST00000429429_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_1719nt ATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCTTTACCACTCCTGAAGGCCCTAAACCCCGT TCCAGATGCTCTGACTGGGCAAGTGCAGTTGAAGAAGATGAAATGAGGACCAGAGTTAACAAAGAAATGGCAAGATATAAAAGGAAACTC CTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCAGGAAGTTCTGATTCAAAGGAGTCTATGTCTACTGTGCCGGCTGACTTTGAG ACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATCAACTATGGGAAGAACACAATTGCCTACGATCGTTATATTAAAGAAGTCCCA AGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCTAATAAATTTAAGAAGTATAGTCGACGTTCATGGGACCAGCAAATCAAACTC TGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAAGAAGGATGTGATTTGCAAGAAATACACCCTGTAGACCTTGAATCTGCAGAA AGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTTCTGATTGCTGAGGAAGGGGTGGACAGCCTGAATGTCAAGGAGCTGCAGGCA GCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACGGAAGACCGCCTGAGGGGTCAGCTGAAGCAGTGGCTGGACCTGCACCTGCAT CAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCCATGTACCTCCCGGACACCCTCTCTCCAGCCGACCAGCTCAAGTCCACACTG CAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTGAAAGTGGCCGAGGTGGAGGGCGAGCAGGTGGACAACAAGGCCAAGCTGGAG GCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCACCGTGAGAAGGAGCTGCAGAAGCGCTCGGAGGTGGCGAAGGATTTTGAGCCC GAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAGCCACAGCCAGAAATGCCTGACACAGTCCTGCAGTCAGAGACCTTGAAGGAC ACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATCACGAAGGAGGAAATCGACATCCTCAGCGATGCCTGCTCTAAGCTGCAGGAG CAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAGCTGCTGAAGGAGGATGTGCAGGACTACAGCGAGGACTTGCAGGAGATCAAG AAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAAGAATCTAAAGCCAGCAAGAGATTGACAAAAAGGGTGCAGCAAATGATCGGG CAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAGCAGGCTGGCAAGCTGGCCCCGGCCAACGGCATGCCCACGGGGGAGAACGTC ATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTGGATGAA AACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGCCAGGTG GCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCAGAGGTG >In-frame_SLBP_ENST00000489418_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_1836nt ATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGA CGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGCTTT ACCACTCCTGAAGGCCCTAAACCCCGTTCCAGATGCTCTGACTGGGCAAGTGCAGTTGAAGAAGATGAAATGAGGACCAGAGTTAACAAA GAAATGGCAAGATATAAAAGGAAACTCCTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCAGGAAGTTCTGATTCAAAGGAGTCT ATGTCTACTGTGCCGGCTGACTTTGAGACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATCAACTATGGGAAGAACACAATTGCC TACGATCGTTATATTAAAGAAGTCCCAAGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCTAATAAATTTAAGAAGTATAGTCGA CGTTCATGGGACCAGCAAATCAAACTCTGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAAGAAGGATGTGATTTGCAAGAAATA CACCCTGTAGACCTTGAATCTGCAGAAAGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTTCTGATTGCTGAGGAAGGGGTGGAC AGCCTGAATGTCAAGGAGCTGCAGGCAGCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACGGAAGACCGCCTGAGGGGTCAGCTG AAGCAGTGGCTGGACCTGCACCTGCATCAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCCATGTACCTCCCGGACACCCTCTCT CCAGCCGACCAGCTCAAGTCCACACTGCAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTGAAAGTGGCCGAGGTGGAGGGCGAG CAGGTGGACAACAAGGCCAAGCTGGAGGCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCACCGTGAGAAGGAGCTGCAGAAGCGC TCGGAGGTGGCGAAGGATTTTGAGCCCGAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAGCCACAGCCAGAAATGCCTGACACA GTCCTGCAGTCAGAGACCTTGAAGGACACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATCACGAAGGAGGAAATCGACATCCTC AGCGATGCCTGCTCTAAGCTGCAGGAGCAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAGCTGCTGAAGGAGGATGTGCAGGAC TACAGCGAGGACTTGCAGGAGATCAAGAAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAAGAATCTAAAGCCAGCAAGAGATTG ACAAAAAGGGTGCAGCAAATGATCGGGCAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAGCAGGCTGGCAAGCTGGCCCCGGCC AACGGCATGCCCACGGGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTC ACCAGCCTGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAA GATGTTCACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAG >In-frame_SLBP_ENST00000318386_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_1857nt ATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGA CGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGCTTT ACCACTCCTGAAGGCCCTAAACCCCGTTCCAGATGCTCTGACTGGGCAAGTGCAGTTGAAGAAGATGAAATGAGGACCAGAGTTAACAAA GAAATGGCAAGCAATATTTATTTTGCCCTCAGATATAAAAGGAAACTCCTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCAGGA AGTTCTGATTCAAAGGAGTCTATGTCTACTGTGCCGGCTGACTTTGAGACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATCAAC TATGGGAAGAACACAATTGCCTACGATCGTTATATTAAAGAAGTCCCAAGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCTAAT AAATTTAAGAAGTATAGTCGACGTTCATGGGACCAGCAAATCAAACTCTGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAAGAA GGATGTGATTTGCAAGAAATACACCCTGTAGACCTTGAATCTGCAGAAAGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTTCTG ATTGCTGAGGAAGGGGTGGACAGCCTGAATGTCAAGGAGCTGCAGGCAGCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACGGAA GACCGCCTGAGGGGTCAGCTGAAGCAGTGGCTGGACCTGCACCTGCATCAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCCATG TACCTCCCGGACACCCTCTCTCCAGCCGACCAGCTCAAGTCCACACTGCAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTGAAA GTGGCCGAGGTGGAGGGCGAGCAGGTGGACAACAAGGCCAAGCTGGAGGCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCACCGT GAGAAGGAGCTGCAGAAGCGCTCGGAGGTGGCGAAGGATTTTGAGCCCGAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAGCCA CAGCCAGAAATGCCTGACACAGTCCTGCAGTCAGAGACCTTGAAGGACACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATCACG AAGGAGGAAATCGACATCCTCAGCGATGCCTGCTCTAAGCTGCAGGAGCAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAGCTG CTGAAGGAGGATGTGCAGGACTACAGCGAGGACTTGCAGGAGATCAAGAAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAAGAA TCTAAAGCCAGCAAGAGATTGACAAAAAGGGTGCAGCAAATGATCGGGCAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAGCAG GCTGGCAAGCTGGCCCCGGCCAACGGCATGCCCACGGGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAG CACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTG ATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAG >In-frame_SLBP_ENST00000488267_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_1731nt ATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGA CGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGATAT AAAAGGAAACTCCTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCAGGAAGTTCTGATTCAAAGGAGTCTATGTCTACTGTGCCG GCTGACTTTGAGACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATCAACTATGGGAAGAACACAATTGCCTACGATCGTTATATT AAAGAAGTCCCAAGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCTAATAAATTTAAGAAGTATAGTCGACGTTCATGGGACCAG CAAATCAAACTCTGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAAGAAGGATGTGATTTGCAAGAAATACACCCTGTAGACCTT GAATCTGCAGAAAGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTTCTGATTGCTGAGGAAGGGGTGGACAGCCTGAATGTCAAG GAGCTGCAGGCAGCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACGGAAGACCGCCTGAGGGGTCAGCTGAAGCAGTGGCTGGAC CTGCACCTGCATCAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCCATGTACCTCCCGGACACCCTCTCTCCAGCCGACCAGCTC AAGTCCACACTGCAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTGAAAGTGGCCGAGGTGGAGGGCGAGCAGGTGGACAACAAG GCCAAGCTGGAGGCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCACCGTGAGAAGGAGCTGCAGAAGCGCTCGGAGGTGGCGAAG GATTTTGAGCCCGAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAGCCACAGCCAGAAATGCCTGACACAGTCCTGCAGTCAGAG ACCTTGAAGGACACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATCACGAAGGAGGAAATCGACATCCTCAGCGATGCCTGCTCT AAGCTGCAGGAGCAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAGCTGCTGAAGGAGGATGTGCAGGACTACAGCGAGGACTTG CAGGAGATCAAGAAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAAGAATCTAAAGCCAGCAAGAGATTGACAAAAAGGGTGCAG CAAATGATCGGGCAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAGCAGGCTGGCAAGCTGGCCCCGGCCAACGGCATGCCCACG GGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCA GCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCC ACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAG >In-frame_SLBP_ENST00000489418_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_465nt ATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGA CGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGGGAG AACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTG GATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGC CAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCA >In-frame_SLBP_ENST00000318386_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_465nt ATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGA CGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGGGAG AACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTG GATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGC CAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCA >In-frame_SLBP_ENST00000488267_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_465nt ATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGA CGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGGGAG AACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTG GATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGC CAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SLBP_ENST00000429429_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_4794nt GAGCTCGTGAGCGCCGGCGCGGGGACGCGGGTTTCTGCCTCAGGCCCTGCCCTGCTCTACTCTGCGCTCTCTGCCCGCGCCGCCGCCGCC TCAGCCTCGGCCCTGCGCTGCGCGCCCGGCCCGTGCTGCCATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGG TGACGCCAGCTTTACCACTCCTGAAGGCCCTAAACCCCGTTCCAGATGCTCTGACTGGGCAAGTGCAGTTGAAGAAGATGAAATGAGGAC CAGAGTTAACAAAGAAATGGCAAGATATAAAAGGAAACTCCTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCAGGAAGTTCTGA TTCAAAGGAGTCTATGTCTACTGTGCCGGCTGACTTTGAGACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATCAACTATGGGAA GAACACAATTGCCTACGATCGTTATATTAAAGAAGTCCCAAGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCTAATAAATTTAA GAAGTATAGTCGACGTTCATGGGACCAGCAAATCAAACTCTGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAAGAAGGATGTGA TTTGCAAGAAATACACCCTGTAGACCTTGAATCTGCAGAAAGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTTCTGATTGCTGA GGAAGGGGTGGACAGCCTGAATGTCAAGGAGCTGCAGGCAGCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACGGAAGACCGCCT GAGGGGTCAGCTGAAGCAGTGGCTGGACCTGCACCTGCATCAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCCATGTACCTCCC GGACACCCTCTCTCCAGCCGACCAGCTCAAGTCCACACTGCAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTGAAAGTGGCCGA GGTGGAGGGCGAGCAGGTGGACAACAAGGCCAAGCTGGAGGCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCACCGTGAGAAGGA GCTGCAGAAGCGCTCGGAGGTGGCGAAGGATTTTGAGCCCGAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAGCCACAGCCAGA AATGCCTGACACAGTCCTGCAGTCAGAGACCTTGAAGGACACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATCACGAAGGAGGA AATCGACATCCTCAGCGATGCCTGCTCTAAGCTGCAGGAGCAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAGCTGCTGAAGGA GGATGTGCAGGACTACAGCGAGGACTTGCAGGAGATCAAGAAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAAGAATCTAAAGC CAGCAAGAGATTGACAAAAAGGGTGCAGCAAATGATCGGGCAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAGCAGGCTGGCAA GCTGGCCCCGGCCAACGGCATGCCCACGGGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCC CGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCT GGTGGACAAAGAAGATGTTCACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGA GAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCAGAGGTGAAGAGCTAGAACCACTGGCCTGGGCACCTGTCCTCCTGCTGTGCCGTCAC CCTGGCAAGGGCCGTGAGGGCGATTGCTTTGTGGTGATTCTCAGTGGCTCATCTAATATTTTGGCTGGAATAAATCAGAGACTTCCATAA TCAAGTAAATTTTAATTTTCATCATTCCACGGAGATTCAGTCTGTCTGGAATCCCGGAACCCCTCCACAGAATCGTGTCTGGATCCACAC TGTGGTGTGGCTGCCACGGCCTCCTGGCTCCAGAGGCAGCTGGGCTGGGCCAAGGCAGGAAGGCGCCCCCATGTGTGTGGCCTCAGTCTC AGCATCTGACTGTGCTGCCCTGTCCCCAGGGAAGAGAATGAGGACCACGTGGACTCCGCCCACACAGAGCTGGCTGCTGTGCCCACCCTC AGGGGCGTCAGGAGACACAGCCTGGCCTCCTCAGGGCTGAAGATGCCTCCATTCGCCTGTGGACCTTGATTTCTAGATTTCAGTGTCAAT AGACCTGTCTTCCTGCACACTTTCAGTTGGATGTGGGTCATTGTGGAGACAGAGGTGTCTGCCATCTCTGTGGCCTCTGGAGAGTGACGT CTCCCTGCTGGGAGTGCTGGTTCTCACGTGCGGTTTCCCTTGTGTATCGGAGCTCTTTCTCGGCTTTCTATTTCCCCCAGTTCTTTAAGC AGTCAATTGGCACAGAGTTTCCCACGGGGGCTGCAGTGGATTCACTGTGTCAGGGATGAGCCTGGCTTGGGGGTTGGTGGGGCTCTGAAG CGCATTTGGGGTTCTTTGTAGCTTCTAATGTGAGGTTTGAGTCCAGTGCGCCCACAGCAGCATGCCCTTCTCACCCCTTGCAGTGTTGCA GGCTCAGGCCCCTGGGCTCCTTCAGCAAGCAGGCTAGTCAATGAGGCATGAGGATCCGGCACAGGGCATCCCCTGGGGCTTCAAGGGCAA TACCCCCGTGCTTAGGGTTTGCCCTGTGCCCTCTGGGTGGGGTGGCCTCCCCGCACTCGGCAGCATGGCCAGGCTGGCCAGGGCGTGGGC AGGTGGTGTCCTGTGGCACCTCCATCCTCCTGCCCAGCCGGCTGTGTCACACTCATCTTTTTAAGGTCAGGTTGGTTCCTGGCAAAAATG TACCTCCAGGGGCCTCCAAGCATAGGATTTGGAAGACAGGAACGGCACAGGCGTCCAGGAAAGCAGCTGCACTCAGACAATGCCTTCTCC ATTACTTGAAGCTTCTTTCTGTTCAGCCATTAAAGAAACTTGACAAAATAGGAACAGGAGATATTTCTCAATTGTAAACCTTTGTGCAGG GACAGTTGGCTTCCAGAGGCTTTCAGCTTTCAGTTATTTGAGAAGTTTGTTTTAGATCCTTAACTAATATTTATGAATTCTCTCACCCTG TGTAAGTAGCCTGGTGTTCGTTTGTCCAAGTGTACTTACCCTTGAGAACAAGTCTTGCAGTTGCCAGGTGTGTGCAGACGCCTCTCCTGT GAGCGGCATCGCGGGCCCAGTCAGCTGCCCCGGCTCTCATCCTCGTCCTCACTGCCTTGGCTGAGCACTGTTGACGTGAACAGCCACTGC AACAGGCAGCCCATCCCACTGTCCCCTCTGCCCTGGACTCCGCATGGCCTCCAAAAGCCAGCTTGCCCTCCGGGTGCTGCAGGGGCTTTG CAGGTGGGGAAGGCTCTGGTGGGTGCCTTTGGTGGCTTCCGTGACATCAGCCGTGCTCTGATGCAGGCTTGCTCCCTCGTCATTCTCCCT CGTCATTCTCCCTCATCGTTCTGTGTGCATTTTTCTCTATGTCCTGACCTTTCTTCTTGCACCTAAAAGTGGTGTCTGGGTGCAAATGTA AGCAGTGGTGGATCCAGAAATATGAGCTTTGTGTAATAAGCTTCTTAAAACAGTCCTTTCTTACACCTGCCCAGGGCCAGACCCTCGGTC TTGGCCTTTTTCAGGAGCTAGGATATCTGCGCCTGGTGAAAATGAAACGAATTCCTGATTTAGGAATTCAGTGTTTCCTCCTCACTCCAG CTAAGCACTCACTTTTTTTTTTTTTTTTTTTTTTTTTTGATACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTCG GCTCACTGCAAGCTCCACCTCCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAATTGGGATTACAGGCATGCGCCACCATGCC CAGCTAATTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCCAGCT CCGCTTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCCAGGACTACAAGCACCCGCCACCACACCTGGCTAATTTTTTT GTATTTTTATTAGAGACAGTGTTTTACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTACTCACCTCGGCCTCCCAAAG TGCTGGGATTACGGGCAAGTTTTTATTAGAGATGGGGTTTCATCATGTTGGTCAGGCTGGTCTTCAACTCCTGACCTCAGGTGATCCACC CGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTGAACTCTCAGTTCTAACGCAGGGATTCAGGAATTG GGCTTTCAGACTCCTTCTGCAGTGTCACAGTCCAGACTTTTTTTAAATGAAGGACACCCCGCAGTGGCTCACAGTGGGTCCCAGGGCTAG CAGGAGCGTGCTGGGGAGCCGGCTCTGTCTTTGTTCGCAGTGGGTCCCGGTGCTGGCAGGAGTGTGCTGGTGAGCCGGCTCTGTCTTTGT AAATCCTTCAGGGGTCCTACGGCTGACTCCACCGGACAGCCCGTCCTGGGCCGTGTTAAGCACCTTTTGTAGAAATCGTATTTTTATTAA >In-frame_SLBP_ENST00000489418_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_5148nt AGGCCTCTCCTCAGCCCACGGCGTCCATCTGGCTCCCGAGCCGAGGGCCGGGCAGTCGGGCTTCGCGGCTGCCCGCGGTCCCGAGGCCTC GCCCTAGCCCCAGTCGGCTCGCGAGGCGCGCACAGCTGAGTGGACCCCTGCGGCGTGGCCCGATGGTCTCGCCCGACCCGGCGCGCGCGG GAGGCCGAGGGGCGGGGCCCGGCGCCCACATAAAGGCGGTTGGGGGCGGGGCGCGCAGAGCTCGTGAGCGCCGGCGCGGGGACGCGGGTT TCTGCCTCAGGCCCTGCCCTGCTCTACTCTGCGCTCTCTGCCCGCGCCGCCGCCGCCTCAGCCTCGGCCCTGCGCTGCGCGCCCGGCCCG TGCTGCCATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAG CCTGGGACGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGA GAGCTTTACCACTCCTGAAGGCCCTAAACCCCGTTCCAGATGCTCTGACTGGGCAAGTGCAGTTGAAGAAGATGAAATGAGGACCAGAGT TAACAAAGAAATGGCAAGATATAAAAGGAAACTCCTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCAGGAAGTTCTGATTCAAA GGAGTCTATGTCTACTGTGCCGGCTGACTTTGAGACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATCAACTATGGGAAGAACAC AATTGCCTACGATCGTTATATTAAAGAAGTCCCAAGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCTAATAAATTTAAGAAGTA TAGTCGACGTTCATGGGACCAGCAAATCAAACTCTGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAAGAAGGATGTGATTTGCA AGAAATACACCCTGTAGACCTTGAATCTGCAGAAAGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTTCTGATTGCTGAGGAAGG GGTGGACAGCCTGAATGTCAAGGAGCTGCAGGCAGCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACGGAAGACCGCCTGAGGGG TCAGCTGAAGCAGTGGCTGGACCTGCACCTGCATCAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCCATGTACCTCCCGGACAC CCTCTCTCCAGCCGACCAGCTCAAGTCCACACTGCAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTGAAAGTGGCCGAGGTGGA GGGCGAGCAGGTGGACAACAAGGCCAAGCTGGAGGCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCACCGTGAGAAGGAGCTGCA GAAGCGCTCGGAGGTGGCGAAGGATTTTGAGCCCGAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAGCCACAGCCAGAAATGCC TGACACAGTCCTGCAGTCAGAGACCTTGAAGGACACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATCACGAAGGAGGAAATCGA CATCCTCAGCGATGCCTGCTCTAAGCTGCAGGAGCAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAGCTGCTGAAGGAGGATGT GCAGGACTACAGCGAGGACTTGCAGGAGATCAAGAAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAAGAATCTAAAGCCAGCAA GAGATTGACAAAAAGGGTGCAGCAAATGATCGGGCAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAGCAGGCTGGCAAGCTGGC CCCGGCCAACGGCATGCCCACGGGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAG CAAGCTCACCAGCCTGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGA CAAAGAAGATGTTCACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGC CAAAGAGAAGGCAGAGAAGGAGGTCGCAGAGGTGAAGAGCTAGAACCACTGGCCTGGGCACCTGTCCTCCTGCTGTGCCGTCACCCTGGC AAGGGCCGTGAGGGCGATTGCTTTGTGGTGATTCTCAGTGGCTCATCTAATATTTTGGCTGGAATAAATCAGAGACTTCCATAATCAAGT AAATTTTAATTTTCATCATTCCACGGAGATTCAGTCTGTCTGGAATCCCGGAACCCCTCCACAGAATCGTGTCTGGATCCACACTGTGGT GTGGCTGCCACGGCCTCCTGGCTCCAGAGGCAGCTGGGCTGGGCCAAGGCAGGAAGGCGCCCCCATGTGTGTGGCCTCAGTCTCAGCATC TGACTGTGCTGCCCTGTCCCCAGGGAAGAGAATGAGGACCACGTGGACTCCGCCCACACAGAGCTGGCTGCTGTGCCCACCCTCAGGGGC GTCAGGAGACACAGCCTGGCCTCCTCAGGGCTGAAGATGCCTCCATTCGCCTGTGGACCTTGATTTCTAGATTTCAGTGTCAATAGACCT GTCTTCCTGCACACTTTCAGTTGGATGTGGGTCATTGTGGAGACAGAGGTGTCTGCCATCTCTGTGGCCTCTGGAGAGTGACGTCTCCCT GCTGGGAGTGCTGGTTCTCACGTGCGGTTTCCCTTGTGTATCGGAGCTCTTTCTCGGCTTTCTATTTCCCCCAGTTCTTTAAGCAGTCAA TTGGCACAGAGTTTCCCACGGGGGCTGCAGTGGATTCACTGTGTCAGGGATGAGCCTGGCTTGGGGGTTGGTGGGGCTCTGAAGCGCATT TGGGGTTCTTTGTAGCTTCTAATGTGAGGTTTGAGTCCAGTGCGCCCACAGCAGCATGCCCTTCTCACCCCTTGCAGTGTTGCAGGCTCA GGCCCCTGGGCTCCTTCAGCAAGCAGGCTAGTCAATGAGGCATGAGGATCCGGCACAGGGCATCCCCTGGGGCTTCAAGGGCAATACCCC CGTGCTTAGGGTTTGCCCTGTGCCCTCTGGGTGGGGTGGCCTCCCCGCACTCGGCAGCATGGCCAGGCTGGCCAGGGCGTGGGCAGGTGG TGTCCTGTGGCACCTCCATCCTCCTGCCCAGCCGGCTGTGTCACACTCATCTTTTTAAGGTCAGGTTGGTTCCTGGCAAAAATGTACCTC CAGGGGCCTCCAAGCATAGGATTTGGAAGACAGGAACGGCACAGGCGTCCAGGAAAGCAGCTGCACTCAGACAATGCCTTCTCCATTACT TGAAGCTTCTTTCTGTTCAGCCATTAAAGAAACTTGACAAAATAGGAACAGGAGATATTTCTCAATTGTAAACCTTTGTGCAGGGACAGT TGGCTTCCAGAGGCTTTCAGCTTTCAGTTATTTGAGAAGTTTGTTTTAGATCCTTAACTAATATTTATGAATTCTCTCACCCTGTGTAAG TAGCCTGGTGTTCGTTTGTCCAAGTGTACTTACCCTTGAGAACAAGTCTTGCAGTTGCCAGGTGTGTGCAGACGCCTCTCCTGTGAGCGG CATCGCGGGCCCAGTCAGCTGCCCCGGCTCTCATCCTCGTCCTCACTGCCTTGGCTGAGCACTGTTGACGTGAACAGCCACTGCAACAGG CAGCCCATCCCACTGTCCCCTCTGCCCTGGACTCCGCATGGCCTCCAAAAGCCAGCTTGCCCTCCGGGTGCTGCAGGGGCTTTGCAGGTG GGGAAGGCTCTGGTGGGTGCCTTTGGTGGCTTCCGTGACATCAGCCGTGCTCTGATGCAGGCTTGCTCCCTCGTCATTCTCCCTCGTCAT TCTCCCTCATCGTTCTGTGTGCATTTTTCTCTATGTCCTGACCTTTCTTCTTGCACCTAAAAGTGGTGTCTGGGTGCAAATGTAAGCAGT GGTGGATCCAGAAATATGAGCTTTGTGTAATAAGCTTCTTAAAACAGTCCTTTCTTACACCTGCCCAGGGCCAGACCCTCGGTCTTGGCC TTTTTCAGGAGCTAGGATATCTGCGCCTGGTGAAAATGAAACGAATTCCTGATTTAGGAATTCAGTGTTTCCTCCTCACTCCAGCTAAGC ACTCACTTTTTTTTTTTTTTTTTTTTTTTTTTGATACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCAC TGCAAGCTCCACCTCCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAATTGGGATTACAGGCATGCGCCACCATGCCCAGCTA ATTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCCAGCTCCGCTT CCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCCAGGACTACAAGCACCCGCCACCACACCTGGCTAATTTTTTTGTATTT TTATTAGAGACAGTGTTTTACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTACTCACCTCGGCCTCCCAAAGTGCTGG GATTACGGGCAAGTTTTTATTAGAGATGGGGTTTCATCATGTTGGTCAGGCTGGTCTTCAACTCCTGACCTCAGGTGATCCACCCGCCTC AGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTGAACTCTCAGTTCTAACGCAGGGATTCAGGAATTGGGCTTT CAGACTCCTTCTGCAGTGTCACAGTCCAGACTTTTTTTAAATGAAGGACACCCCGCAGTGGCTCACAGTGGGTCCCAGGGCTAGCAGGAG CGTGCTGGGGAGCCGGCTCTGTCTTTGTTCGCAGTGGGTCCCGGTGCTGGCAGGAGTGTGCTGGTGAGCCGGCTCTGTCTTTGTAAATCC TTCAGGGGTCCTACGGCTGACTCCACCGGACAGCCCGTCCTGGGCCGTGTTAAGCACCTTTTGTAGAAATCGTATTTTTATTAAAACATC >In-frame_SLBP_ENST00000318386_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_4864nt CTCTGCCCGCGCCGCCGCCGCCTCAGCCTCGGCCCTGCGCTGCGCGCCCGGCCCGTGCTGCCATGGCCTGCCGCCCGCGAAGCCCGCCGA GGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGACGGAAGCGCAGAGCCGACGGCAGGCGCT GGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGCTTTACCACTCCTGAAGGCCCTAAACCCCGTT CCAGATGCTCTGACTGGGCAAGTGCAGTTGAAGAAGATGAAATGAGGACCAGAGTTAACAAAGAAATGGCAAGCAATATTTATTTTGCCC TCAGATATAAAAGGAAACTCCTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCAGGAAGTTCTGATTCAAAGGAGTCTATGTCTA CTGTGCCGGCTGACTTTGAGACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATCAACTATGGGAAGAACACAATTGCCTACGATC GTTATATTAAAGAAGTCCCAAGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCTAATAAATTTAAGAAGTATAGTCGACGTTCAT GGGACCAGCAAATCAAACTCTGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAAGAAGGATGTGATTTGCAAGAAATACACCCTG TAGACCTTGAATCTGCAGAAAGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTTCTGATTGCTGAGGAAGGGGTGGACAGCCTGA ATGTCAAGGAGCTGCAGGCAGCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACGGAAGACCGCCTGAGGGGTCAGCTGAAGCAGT GGCTGGACCTGCACCTGCATCAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCCATGTACCTCCCGGACACCCTCTCTCCAGCCG ACCAGCTCAAGTCCACACTGCAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTGAAAGTGGCCGAGGTGGAGGGCGAGCAGGTGG ACAACAAGGCCAAGCTGGAGGCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCACCGTGAGAAGGAGCTGCAGAAGCGCTCGGAGG TGGCGAAGGATTTTGAGCCCGAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAGCCACAGCCAGAAATGCCTGACACAGTCCTGC AGTCAGAGACCTTGAAGGACACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATCACGAAGGAGGAAATCGACATCCTCAGCGATG CCTGCTCTAAGCTGCAGGAGCAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAGCTGCTGAAGGAGGATGTGCAGGACTACAGCG AGGACTTGCAGGAGATCAAGAAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAAGAATCTAAAGCCAGCAAGAGATTGACAAAAA GGGTGCAGCAAATGATCGGGCAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAGCAGGCTGGCAAGCTGGCCCCGGCCAACGGCA TGCCCACGGGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCC TGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTC ACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAG AGAAGGAGGTCGCAGAGGTGAAGAGCTAGAACCACTGGCCTGGGCACCTGTCCTCCTGCTGTGCCGTCACCCTGGCAAGGGCCGTGAGGG CGATTGCTTTGTGGTGATTCTCAGTGGCTCATCTAATATTTTGGCTGGAATAAATCAGAGACTTCCATAATCAAGTAAATTTTAATTTTC ATCATTCCACGGAGATTCAGTCTGTCTGGAATCCCGGAACCCCTCCACAGAATCGTGTCTGGATCCACACTGTGGTGTGGCTGCCACGGC CTCCTGGCTCCAGAGGCAGCTGGGCTGGGCCAAGGCAGGAAGGCGCCCCCATGTGTGTGGCCTCAGTCTCAGCATCTGACTGTGCTGCCC TGTCCCCAGGGAAGAGAATGAGGACCACGTGGACTCCGCCCACACAGAGCTGGCTGCTGTGCCCACCCTCAGGGGCGTCAGGAGACACAG CCTGGCCTCCTCAGGGCTGAAGATGCCTCCATTCGCCTGTGGACCTTGATTTCTAGATTTCAGTGTCAATAGACCTGTCTTCCTGCACAC TTTCAGTTGGATGTGGGTCATTGTGGAGACAGAGGTGTCTGCCATCTCTGTGGCCTCTGGAGAGTGACGTCTCCCTGCTGGGAGTGCTGG TTCTCACGTGCGGTTTCCCTTGTGTATCGGAGCTCTTTCTCGGCTTTCTATTTCCCCCAGTTCTTTAAGCAGTCAATTGGCACAGAGTTT CCCACGGGGGCTGCAGTGGATTCACTGTGTCAGGGATGAGCCTGGCTTGGGGGTTGGTGGGGCTCTGAAGCGCATTTGGGGTTCTTTGTA GCTTCTAATGTGAGGTTTGAGTCCAGTGCGCCCACAGCAGCATGCCCTTCTCACCCCTTGCAGTGTTGCAGGCTCAGGCCCCTGGGCTCC TTCAGCAAGCAGGCTAGTCAATGAGGCATGAGGATCCGGCACAGGGCATCCCCTGGGGCTTCAAGGGCAATACCCCCGTGCTTAGGGTTT GCCCTGTGCCCTCTGGGTGGGGTGGCCTCCCCGCACTCGGCAGCATGGCCAGGCTGGCCAGGGCGTGGGCAGGTGGTGTCCTGTGGCACC TCCATCCTCCTGCCCAGCCGGCTGTGTCACACTCATCTTTTTAAGGTCAGGTTGGTTCCTGGCAAAAATGTACCTCCAGGGGCCTCCAAG CATAGGATTTGGAAGACAGGAACGGCACAGGCGTCCAGGAAAGCAGCTGCACTCAGACAATGCCTTCTCCATTACTTGAAGCTTCTTTCT GTTCAGCCATTAAAGAAACTTGACAAAATAGGAACAGGAGATATTTCTCAATTGTAAACCTTTGTGCAGGGACAGTTGGCTTCCAGAGGC TTTCAGCTTTCAGTTATTTGAGAAGTTTGTTTTAGATCCTTAACTAATATTTATGAATTCTCTCACCCTGTGTAAGTAGCCTGGTGTTCG TTTGTCCAAGTGTACTTACCCTTGAGAACAAGTCTTGCAGTTGCCAGGTGTGTGCAGACGCCTCTCCTGTGAGCGGCATCGCGGGCCCAG TCAGCTGCCCCGGCTCTCATCCTCGTCCTCACTGCCTTGGCTGAGCACTGTTGACGTGAACAGCCACTGCAACAGGCAGCCCATCCCACT GTCCCCTCTGCCCTGGACTCCGCATGGCCTCCAAAAGCCAGCTTGCCCTCCGGGTGCTGCAGGGGCTTTGCAGGTGGGGAAGGCTCTGGT GGGTGCCTTTGGTGGCTTCCGTGACATCAGCCGTGCTCTGATGCAGGCTTGCTCCCTCGTCATTCTCCCTCGTCATTCTCCCTCATCGTT CTGTGTGCATTTTTCTCTATGTCCTGACCTTTCTTCTTGCACCTAAAAGTGGTGTCTGGGTGCAAATGTAAGCAGTGGTGGATCCAGAAA TATGAGCTTTGTGTAATAAGCTTCTTAAAACAGTCCTTTCTTACACCTGCCCAGGGCCAGACCCTCGGTCTTGGCCTTTTTCAGGAGCTA GGATATCTGCGCCTGGTGAAAATGAAACGAATTCCTGATTTAGGAATTCAGTGTTTCCTCCTCACTCCAGCTAAGCACTCACTTTTTTTT TTTTTTTTTTTTTTTTTTGATACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAAGCTCCACCT CCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAATTGGGATTACAGGCATGCGCCACCATGCCCAGCTAATTTTTTTTTTTTT TTTTGAGACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCCAGCTCCGCTTCCTGGGTTCACGCC ATTCTCCTGCCTCAGCCTCCCGAGTAGCCAGGACTACAAGCACCCGCCACCACACCTGGCTAATTTTTTTGTATTTTTATTAGAGACAGT GTTTTACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTACTCACCTCGGCCTCCCAAAGTGCTGGGATTACGGGCAAGT TTTTATTAGAGATGGGGTTTCATCATGTTGGTCAGGCTGGTCTTCAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTG CTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTGAACTCTCAGTTCTAACGCAGGGATTCAGGAATTGGGCTTTCAGACTCCTTCTGC AGTGTCACAGTCCAGACTTTTTTTAAATGAAGGACACCCCGCAGTGGCTCACAGTGGGTCCCAGGGCTAGCAGGAGCGTGCTGGGGAGCC GGCTCTGTCTTTGTTCGCAGTGGGTCCCGGTGCTGGCAGGAGTGTGCTGGTGAGCCGGCTCTGTCTTTGTAAATCCTTCAGGGGTCCTAC GGCTGACTCCACCGGACAGCCCGTCCTGGGCCGTGTTAAGCACCTTTTGTAGAAATCGTATTTTTATTAAAACATCAAATCTGTGTTCCT >In-frame_SLBP_ENST00000488267_chr4_1696501_-_LETM1_ENST00000302787_chr4_1827410_-_4805nt AGCTCGTGAGCGCCGGCGCGGGGACGCGGGTTTCTGCCTCAGGCCCTGCCCTGCTCTACTCTGCGCTCTCTGCCCGCGCCGCCGCCGCCT CAGCCTCGGCCCTGCGCTGCGCGCCCGGCCCGTGCTGCCATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGT GACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGACGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAG GCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGATATAAAAGGAAACTCCTCATCAATGACTTTGGAAGAGAGAGAAAATCATCATCA GGAAGTTCTGATTCAAAGGAGTCTATGTCTACTGTGCCGGCTGACTTTGAGACAGATGAAAGTGTCCTAATGAGGAGACAGAAGCAGATC AACTATGGGAAGAACACAATTGCCTACGATCGTTATATTAAAGAAGTCCCAAGACACCTTCGACAACCTGGCATTCATCCCAAGACCCCT AATAAATTTAAGAAGTATAGTCGACGTTCATGGGACCAGCAAATCAAACTCTGGAAGGTGGCTCTGCATTTTTGGGATCCTCCAGCGGAA GAAGGATGTGATTTGCAAGAAATACACCCTGTAGACCTTGAATCTGCAGAAAGCAGCTCCGAGCCCCAGACCAGCTCTCAGGATGACTTT CTGATTGCTGAGGAAGGGGTGGACAGCCTGAATGTCAAGGAGCTGCAGGCAGCGTGTCGGGCACGAGGCATGCGGGCCCTGGGCGTCACG GAAGACCGCCTGAGGGGTCAGCTGAAGCAGTGGCTGGACCTGCACCTGCATCAGGAGATCCCCACATCGCTGCTCATCCTGTCCCGGGCC ATGTACCTCCCGGACACCCTCTCTCCAGCCGACCAGCTCAAGTCCACACTGCAGACCCTCCCAGAGATTGTGGCAAAGGAAGCACAGGTG AAAGTGGCCGAGGTGGAGGGCGAGCAGGTGGACAACAAGGCCAAGCTGGAGGCCACGCTGCAGGAGGAGGCGGCCATCCAGCAGGAGCAC CGTGAGAAGGAGCTGCAGAAGCGCTCGGAGGTGGCGAAGGATTTTGAGCCCGAACGTGTGGTAGCTGCTCCCCAAAGGCCGGGGACCGAG CCACAGCCAGAAATGCCTGACACAGTCCTGCAGTCAGAGACCTTGAAGGACACTGCCCCGGTGCTGGAGGGCTTGAAGGAGGAAGAGATC ACGAAGGAGGAAATCGACATCCTCAGCGATGCCTGCTCTAAGCTGCAGGAGCAGAAGAAGTCACTCACCAAGGAGAAGGAGGAGCTGGAG CTGCTGAAGGAGGATGTGCAGGACTACAGCGAGGACTTGCAGGAGATCAAGAAGGAACTTTCAAAGACTGGTGAAGAAAAGTACGTGGAA GAATCTAAAGCCAGCAAGAGATTGACAAAAAGGGTGCAGCAAATGATCGGGCAGATCGATGGCTTGATCTCGCAGCTGGAGATGGACCAG CAGGCTGGCAAGCTGGCCCCGGCCAACGGCATGCCCACGGGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTC AAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAG GTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTG GAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCAGAGGTGAAGAGCTAGAACCACTGGCCTGGGCACCTGTCCTCCTGC TGTGCCGTCACCCTGGCAAGGGCCGTGAGGGCGATTGCTTTGTGGTGATTCTCAGTGGCTCATCTAATATTTTGGCTGGAATAAATCAGA GACTTCCATAATCAAGTAAATTTTAATTTTCATCATTCCACGGAGATTCAGTCTGTCTGGAATCCCGGAACCCCTCCACAGAATCGTGTC TGGATCCACACTGTGGTGTGGCTGCCACGGCCTCCTGGCTCCAGAGGCAGCTGGGCTGGGCCAAGGCAGGAAGGCGCCCCCATGTGTGTG GCCTCAGTCTCAGCATCTGACTGTGCTGCCCTGTCCCCAGGGAAGAGAATGAGGACCACGTGGACTCCGCCCACACAGAGCTGGCTGCTG TGCCCACCCTCAGGGGCGTCAGGAGACACAGCCTGGCCTCCTCAGGGCTGAAGATGCCTCCATTCGCCTGTGGACCTTGATTTCTAGATT TCAGTGTCAATAGACCTGTCTTCCTGCACACTTTCAGTTGGATGTGGGTCATTGTGGAGACAGAGGTGTCTGCCATCTCTGTGGCCTCTG GAGAGTGACGTCTCCCTGCTGGGAGTGCTGGTTCTCACGTGCGGTTTCCCTTGTGTATCGGAGCTCTTTCTCGGCTTTCTATTTCCCCCA GTTCTTTAAGCAGTCAATTGGCACAGAGTTTCCCACGGGGGCTGCAGTGGATTCACTGTGTCAGGGATGAGCCTGGCTTGGGGGTTGGTG GGGCTCTGAAGCGCATTTGGGGTTCTTTGTAGCTTCTAATGTGAGGTTTGAGTCCAGTGCGCCCACAGCAGCATGCCCTTCTCACCCCTT GCAGTGTTGCAGGCTCAGGCCCCTGGGCTCCTTCAGCAAGCAGGCTAGTCAATGAGGCATGAGGATCCGGCACAGGGCATCCCCTGGGGC TTCAAGGGCAATACCCCCGTGCTTAGGGTTTGCCCTGTGCCCTCTGGGTGGGGTGGCCTCCCCGCACTCGGCAGCATGGCCAGGCTGGCC AGGGCGTGGGCAGGTGGTGTCCTGTGGCACCTCCATCCTCCTGCCCAGCCGGCTGTGTCACACTCATCTTTTTAAGGTCAGGTTGGTTCC TGGCAAAAATGTACCTCCAGGGGCCTCCAAGCATAGGATTTGGAAGACAGGAACGGCACAGGCGTCCAGGAAAGCAGCTGCACTCAGACA ATGCCTTCTCCATTACTTGAAGCTTCTTTCTGTTCAGCCATTAAAGAAACTTGACAAAATAGGAACAGGAGATATTTCTCAATTGTAAAC CTTTGTGCAGGGACAGTTGGCTTCCAGAGGCTTTCAGCTTTCAGTTATTTGAGAAGTTTGTTTTAGATCCTTAACTAATATTTATGAATT CTCTCACCCTGTGTAAGTAGCCTGGTGTTCGTTTGTCCAAGTGTACTTACCCTTGAGAACAAGTCTTGCAGTTGCCAGGTGTGTGCAGAC GCCTCTCCTGTGAGCGGCATCGCGGGCCCAGTCAGCTGCCCCGGCTCTCATCCTCGTCCTCACTGCCTTGGCTGAGCACTGTTGACGTGA ACAGCCACTGCAACAGGCAGCCCATCCCACTGTCCCCTCTGCCCTGGACTCCGCATGGCCTCCAAAAGCCAGCTTGCCCTCCGGGTGCTG CAGGGGCTTTGCAGGTGGGGAAGGCTCTGGTGGGTGCCTTTGGTGGCTTCCGTGACATCAGCCGTGCTCTGATGCAGGCTTGCTCCCTCG TCATTCTCCCTCGTCATTCTCCCTCATCGTTCTGTGTGCATTTTTCTCTATGTCCTGACCTTTCTTCTTGCACCTAAAAGTGGTGTCTGG GTGCAAATGTAAGCAGTGGTGGATCCAGAAATATGAGCTTTGTGTAATAAGCTTCTTAAAACAGTCCTTTCTTACACCTGCCCAGGGCCA GACCCTCGGTCTTGGCCTTTTTCAGGAGCTAGGATATCTGCGCCTGGTGAAAATGAAACGAATTCCTGATTTAGGAATTCAGTGTTTCCT CCTCACTCCAGCTAAGCACTCACTTTTTTTTTTTTTTTTTTTTTTTTTTGATACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTG GTGCGATCTCGGCTCACTGCAAGCTCCACCTCCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAATTGGGATTACAGGCATGC GCCACCATGCCCAGCTAATTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCT CACTGCCAGCTCCGCTTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCCAGGACTACAAGCACCCGCCACCACACCTGG CTAATTTTTTTGTATTTTTATTAGAGACAGTGTTTTACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTACTCACCTCG GCCTCCCAAAGTGCTGGGATTACGGGCAAGTTTTTATTAGAGATGGGGTTTCATCATGTTGGTCAGGCTGGTCTTCAACTCCTGACCTCA GGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTGAACTCTCAGTTCTAACGCAGGGA TTCAGGAATTGGGCTTTCAGACTCCTTCTGCAGTGTCACAGTCCAGACTTTTTTTAAATGAAGGACACCCCGCAGTGGCTCACAGTGGGT CCCAGGGCTAGCAGGAGCGTGCTGGGGAGCCGGCTCTGTCTTTGTTCGCAGTGGGTCCCGGTGCTGGCAGGAGTGTGCTGGTGAGCCGGC TCTGTCTTTGTAAATCCTTCAGGGGTCCTACGGCTGACTCCACCGGACAGCCCGTCCTGGGCCGTGTTAAGCACCTTTTGTAGAAATCGT >In-frame_SLBP_ENST00000489418_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_3777nt AGGCCTCTCCTCAGCCCACGGCGTCCATCTGGCTCCCGAGCCGAGGGCCGGGCAGTCGGGCTTCGCGGCTGCCCGCGGTCCCGAGGCCTC GCCCTAGCCCCAGTCGGCTCGCGAGGCGCGCACAGCTGAGTGGACCCCTGCGGCGTGGCCCGATGGTCTCGCCCGACCCGGCGCGCGCGG GAGGCCGAGGGGCGGGGCCCGGCGCCCACATAAAGGCGGTTGGGGGCGGGGCGCGCAGAGCTCGTGAGCGCCGGCGCGGGGACGCGGGTT TCTGCCTCAGGCCCTGCCCTGCTCTACTCTGCGCTCTCTGCCCGCGCCGCCGCCGCCTCAGCCTCGGCCCTGCGCTGCGCGCCCGGCCCG TGCTGCCATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAG CCTGGGACGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGA GAGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGC AGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTC CACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGA GGTCGCAGAGGTGAAGAGCTAGAACCACTGGCCTGGGCACCTGTCCTCCTGCTGTGCCGTCACCCTGGCAAGGGCCGTGAGGGCGATTGC TTTGTGGTGATTCTCAGTGGCTCATCTAATATTTTGGCTGGAATAAATCAGAGACTTCCATAATCAAGTAAATTTTAATTTTCATCATTC CACGGAGATTCAGTCTGTCTGGAATCCCGGAACCCCTCCACAGAATCGTGTCTGGATCCACACTGTGGTGTGGCTGCCACGGCCTCCTGG CTCCAGAGGCAGCTGGGCTGGGCCAAGGCAGGAAGGCGCCCCCATGTGTGTGGCCTCAGTCTCAGCATCTGACTGTGCTGCCCTGTCCCC AGGGAAGAGAATGAGGACCACGTGGACTCCGCCCACACAGAGCTGGCTGCTGTGCCCACCCTCAGGGGCGTCAGGAGACACAGCCTGGCC TCCTCAGGGCTGAAGATGCCTCCATTCGCCTGTGGACCTTGATTTCTAGATTTCAGTGTCAATAGACCTGTCTTCCTGCACACTTTCAGT TGGATGTGGGTCATTGTGGAGACAGAGGTGTCTGCCATCTCTGTGGCCTCTGGAGAGTGACGTCTCCCTGCTGGGAGTGCTGGTTCTCAC GTGCGGTTTCCCTTGTGTATCGGAGCTCTTTCTCGGCTTTCTATTTCCCCCAGTTCTTTAAGCAGTCAATTGGCACAGAGTTTCCCACGG GGGCTGCAGTGGATTCACTGTGTCAGGGATGAGCCTGGCTTGGGGGTTGGTGGGGCTCTGAAGCGCATTTGGGGTTCTTTGTAGCTTCTA ATGTGAGGTTTGAGTCCAGTGCGCCCACAGCAGCATGCCCTTCTCACCCCTTGCAGTGTTGCAGGCTCAGGCCCCTGGGCTCCTTCAGCA AGCAGGCTAGTCAATGAGGCATGAGGATCCGGCACAGGGCATCCCCTGGGGCTTCAAGGGCAATACCCCCGTGCTTAGGGTTTGCCCTGT GCCCTCTGGGTGGGGTGGCCTCCCCGCACTCGGCAGCATGGCCAGGCTGGCCAGGGCGTGGGCAGGTGGTGTCCTGTGGCACCTCCATCC TCCTGCCCAGCCGGCTGTGTCACACTCATCTTTTTAAGGTCAGGTTGGTTCCTGGCAAAAATGTACCTCCAGGGGCCTCCAAGCATAGGA TTTGGAAGACAGGAACGGCACAGGCGTCCAGGAAAGCAGCTGCACTCAGACAATGCCTTCTCCATTACTTGAAGCTTCTTTCTGTTCAGC CATTAAAGAAACTTGACAAAATAGGAACAGGAGATATTTCTCAATTGTAAACCTTTGTGCAGGGACAGTTGGCTTCCAGAGGCTTTCAGC TTTCAGTTATTTGAGAAGTTTGTTTTAGATCCTTAACTAATATTTATGAATTCTCTCACCCTGTGTAAGTAGCCTGGTGTTCGTTTGTCC AAGTGTACTTACCCTTGAGAACAAGTCTTGCAGTTGCCAGGTGTGTGCAGACGCCTCTCCTGTGAGCGGCATCGCGGGCCCAGTCAGCTG CCCCGGCTCTCATCCTCGTCCTCACTGCCTTGGCTGAGCACTGTTGACGTGAACAGCCACTGCAACAGGCAGCCCATCCCACTGTCCCCT CTGCCCTGGACTCCGCATGGCCTCCAAAAGCCAGCTTGCCCTCCGGGTGCTGCAGGGGCTTTGCAGGTGGGGAAGGCTCTGGTGGGTGCC TTTGGTGGCTTCCGTGACATCAGCCGTGCTCTGATGCAGGCTTGCTCCCTCGTCATTCTCCCTCGTCATTCTCCCTCATCGTTCTGTGTG CATTTTTCTCTATGTCCTGACCTTTCTTCTTGCACCTAAAAGTGGTGTCTGGGTGCAAATGTAAGCAGTGGTGGATCCAGAAATATGAGC TTTGTGTAATAAGCTTCTTAAAACAGTCCTTTCTTACACCTGCCCAGGGCCAGACCCTCGGTCTTGGCCTTTTTCAGGAGCTAGGATATC TGCGCCTGGTGAAAATGAAACGAATTCCTGATTTAGGAATTCAGTGTTTCCTCCTCACTCCAGCTAAGCACTCACTTTTTTTTTTTTTTT TTTTTTTTTTTGATACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAAGCTCCACCTCCCGGGT TCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAATTGGGATTACAGGCATGCGCCACCATGCCCAGCTAATTTTTTTTTTTTTTTTTGAG ACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGCCAGCTCCGCTTCCTGGGTTCACGCCATTCTCC TGCCTCAGCCTCCCGAGTAGCCAGGACTACAAGCACCCGCCACCACACCTGGCTAATTTTTTTGTATTTTTATTAGAGACAGTGTTTTAC CGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTACTCACCTCGGCCTCCCAAAGTGCTGGGATTACGGGCAAGTTTTTATT AGAGATGGGGTTTCATCATGTTGGTCAGGCTGGTCTTCAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGAT TACAGGCATGAGCCACCGCGCCCGGCCTGAACTCTCAGTTCTAACGCAGGGATTCAGGAATTGGGCTTTCAGACTCCTTCTGCAGTGTCA CAGTCCAGACTTTTTTTAAATGAAGGACACCCCGCAGTGGCTCACAGTGGGTCCCAGGGCTAGCAGGAGCGTGCTGGGGAGCCGGCTCTG TCTTTGTTCGCAGTGGGTCCCGGTGCTGGCAGGAGTGTGCTGGTGAGCCGGCTCTGTCTTTGTAAATCCTTCAGGGGTCCTACGGCTGAC >In-frame_SLBP_ENST00000318386_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_3472nt CTCTGCCCGCGCCGCCGCCGCCTCAGCCTCGGCCCTGCGCTGCGCGCCCGGCCCGTGCTGCCATGGCCTGCCGCCCGCGAAGCCCGCCGA GGCATCAGAGCCGCTGCGACGGTGACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGACGGAAGCGCAGAGCCGACGGCAGGCGCT GGAGGCCCGAAGACGCCGAGGAGGCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGGGAGAACGTCATCAGTGTCGCTGAGCTCATCA ACGCCATGAAGCAAGTCAAGCACATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACA TCGACGACCTCGTCAAGGTGATTGAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGG AAAAAGAGGAGAAGGTGGAGGAGAAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCAGAGGTGAAGAGCTAGAACCACTGGCCTG GGCACCTGTCCTCCTGCTGTGCCGTCACCCTGGCAAGGGCCGTGAGGGCGATTGCTTTGTGGTGATTCTCAGTGGCTCATCTAATATTTT GGCTGGAATAAATCAGAGACTTCCATAATCAAGTAAATTTTAATTTTCATCATTCCACGGAGATTCAGTCTGTCTGGAATCCCGGAACCC CTCCACAGAATCGTGTCTGGATCCACACTGTGGTGTGGCTGCCACGGCCTCCTGGCTCCAGAGGCAGCTGGGCTGGGCCAAGGCAGGAAG GCGCCCCCATGTGTGTGGCCTCAGTCTCAGCATCTGACTGTGCTGCCCTGTCCCCAGGGAAGAGAATGAGGACCACGTGGACTCCGCCCA CACAGAGCTGGCTGCTGTGCCCACCCTCAGGGGCGTCAGGAGACACAGCCTGGCCTCCTCAGGGCTGAAGATGCCTCCATTCGCCTGTGG ACCTTGATTTCTAGATTTCAGTGTCAATAGACCTGTCTTCCTGCACACTTTCAGTTGGATGTGGGTCATTGTGGAGACAGAGGTGTCTGC CATCTCTGTGGCCTCTGGAGAGTGACGTCTCCCTGCTGGGAGTGCTGGTTCTCACGTGCGGTTTCCCTTGTGTATCGGAGCTCTTTCTCG GCTTTCTATTTCCCCCAGTTCTTTAAGCAGTCAATTGGCACAGAGTTTCCCACGGGGGCTGCAGTGGATTCACTGTGTCAGGGATGAGCC TGGCTTGGGGGTTGGTGGGGCTCTGAAGCGCATTTGGGGTTCTTTGTAGCTTCTAATGTGAGGTTTGAGTCCAGTGCGCCCACAGCAGCA TGCCCTTCTCACCCCTTGCAGTGTTGCAGGCTCAGGCCCCTGGGCTCCTTCAGCAAGCAGGCTAGTCAATGAGGCATGAGGATCCGGCAC AGGGCATCCCCTGGGGCTTCAAGGGCAATACCCCCGTGCTTAGGGTTTGCCCTGTGCCCTCTGGGTGGGGTGGCCTCCCCGCACTCGGCA GCATGGCCAGGCTGGCCAGGGCGTGGGCAGGTGGTGTCCTGTGGCACCTCCATCCTCCTGCCCAGCCGGCTGTGTCACACTCATCTTTTT AAGGTCAGGTTGGTTCCTGGCAAAAATGTACCTCCAGGGGCCTCCAAGCATAGGATTTGGAAGACAGGAACGGCACAGGCGTCCAGGAAA GCAGCTGCACTCAGACAATGCCTTCTCCATTACTTGAAGCTTCTTTCTGTTCAGCCATTAAAGAAACTTGACAAAATAGGAACAGGAGAT ATTTCTCAATTGTAAACCTTTGTGCAGGGACAGTTGGCTTCCAGAGGCTTTCAGCTTTCAGTTATTTGAGAAGTTTGTTTTAGATCCTTA ACTAATATTTATGAATTCTCTCACCCTGTGTAAGTAGCCTGGTGTTCGTTTGTCCAAGTGTACTTACCCTTGAGAACAAGTCTTGCAGTT GCCAGGTGTGTGCAGACGCCTCTCCTGTGAGCGGCATCGCGGGCCCAGTCAGCTGCCCCGGCTCTCATCCTCGTCCTCACTGCCTTGGCT GAGCACTGTTGACGTGAACAGCCACTGCAACAGGCAGCCCATCCCACTGTCCCCTCTGCCCTGGACTCCGCATGGCCTCCAAAAGCCAGC TTGCCCTCCGGGTGCTGCAGGGGCTTTGCAGGTGGGGAAGGCTCTGGTGGGTGCCTTTGGTGGCTTCCGTGACATCAGCCGTGCTCTGAT GCAGGCTTGCTCCCTCGTCATTCTCCCTCGTCATTCTCCCTCATCGTTCTGTGTGCATTTTTCTCTATGTCCTGACCTTTCTTCTTGCAC CTAAAAGTGGTGTCTGGGTGCAAATGTAAGCAGTGGTGGATCCAGAAATATGAGCTTTGTGTAATAAGCTTCTTAAAACAGTCCTTTCTT ACACCTGCCCAGGGCCAGACCCTCGGTCTTGGCCTTTTTCAGGAGCTAGGATATCTGCGCCTGGTGAAAATGAAACGAATTCCTGATTTA GGAATTCAGTGTTTCCTCCTCACTCCAGCTAAGCACTCACTTTTTTTTTTTTTTTTTTTTTTTTTTGATACAGAGTCTCGCTCTGTCACC CAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAAGCTCCACCTCCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAAT TGGGATTACAGGCATGCGCCACCATGCCCAGCTAATTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCA ATGGCGTGATCTCGGCTCACTGCCAGCTCCGCTTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCCAGGACTACAAGCA CCCGCCACCACACCTGGCTAATTTTTTTGTATTTTTATTAGAGACAGTGTTTTACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTC GTGATCTACTCACCTCGGCCTCCCAAAGTGCTGGGATTACGGGCAAGTTTTTATTAGAGATGGGGTTTCATCATGTTGGTCAGGCTGGTC TTCAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTGAACTCT CAGTTCTAACGCAGGGATTCAGGAATTGGGCTTTCAGACTCCTTCTGCAGTGTCACAGTCCAGACTTTTTTTAAATGAAGGACACCCCGC AGTGGCTCACAGTGGGTCCCAGGGCTAGCAGGAGCGTGCTGGGGAGCCGGCTCTGTCTTTGTTCGCAGTGGGTCCCGGTGCTGGCAGGAG TGTGCTGGTGAGCCGGCTCTGTCTTTGTAAATCCTTCAGGGGTCCTACGGCTGACTCCACCGGACAGCCCGTCCTGGGCCGTGTTAAGCA >In-frame_SLBP_ENST00000488267_chr4_1713601_-_LETM1_ENST00000302787_chr4_1817529_-_3539nt AGCTCGTGAGCGCCGGCGCGGGGACGCGGGTTTCTGCCTCAGGCCCTGCCCTGCTCTACTCTGCGCTCTCTGCCCGCGCCGCCGCCGCCT CAGCCTCGGCCCTGCGCTGCGCGCCCGGCCCGTGCTGCCATGGCCTGCCGCCCGCGAAGCCCGCCGAGGCATCAGAGCCGCTGCGACGGT GACGCCAGCCCGCCGTCCCCCGCGCGATGGAGCCTGGGACGGAAGCGCAGAGCCGACGGCAGGCGCTGGAGGCCCGAAGACGCCGAGGAG GCAGAGCACCGCGGCGCCGAGCGCAGACCCGAGAGGGAGAACGTCATCAGTGTCGCTGAGCTCATCAACGCCATGAAGCAAGTCAAGCAC ATTCCCGAAAGCAAGCTCACCAGCCTGGCCGCAGCACTGGATGAAAACAAGGATGGCAAGGTCAACATCGACGACCTCGTCAAGGTGATT GAGCTGGTGGACAAAGAAGATGTTCACATCTCCACCAGCCAGGTGGCTGAGATTGTAGCAACACTGGAAAAAGAGGAGAAGGTGGAGGAG AAGGAGAAGGCCAAAGAGAAGGCAGAGAAGGAGGTCGCAGAGGTGAAGAGCTAGAACCACTGGCCTGGGCACCTGTCCTCCTGCTGTGCC GTCACCCTGGCAAGGGCCGTGAGGGCGATTGCTTTGTGGTGATTCTCAGTGGCTCATCTAATATTTTGGCTGGAATAAATCAGAGACTTC CATAATCAAGTAAATTTTAATTTTCATCATTCCACGGAGATTCAGTCTGTCTGGAATCCCGGAACCCCTCCACAGAATCGTGTCTGGATC CACACTGTGGTGTGGCTGCCACGGCCTCCTGGCTCCAGAGGCAGCTGGGCTGGGCCAAGGCAGGAAGGCGCCCCCATGTGTGTGGCCTCA GTCTCAGCATCTGACTGTGCTGCCCTGTCCCCAGGGAAGAGAATGAGGACCACGTGGACTCCGCCCACACAGAGCTGGCTGCTGTGCCCA CCCTCAGGGGCGTCAGGAGACACAGCCTGGCCTCCTCAGGGCTGAAGATGCCTCCATTCGCCTGTGGACCTTGATTTCTAGATTTCAGTG TCAATAGACCTGTCTTCCTGCACACTTTCAGTTGGATGTGGGTCATTGTGGAGACAGAGGTGTCTGCCATCTCTGTGGCCTCTGGAGAGT GACGTCTCCCTGCTGGGAGTGCTGGTTCTCACGTGCGGTTTCCCTTGTGTATCGGAGCTCTTTCTCGGCTTTCTATTTCCCCCAGTTCTT TAAGCAGTCAATTGGCACAGAGTTTCCCACGGGGGCTGCAGTGGATTCACTGTGTCAGGGATGAGCCTGGCTTGGGGGTTGGTGGGGCTC TGAAGCGCATTTGGGGTTCTTTGTAGCTTCTAATGTGAGGTTTGAGTCCAGTGCGCCCACAGCAGCATGCCCTTCTCACCCCTTGCAGTG TTGCAGGCTCAGGCCCCTGGGCTCCTTCAGCAAGCAGGCTAGTCAATGAGGCATGAGGATCCGGCACAGGGCATCCCCTGGGGCTTCAAG GGCAATACCCCCGTGCTTAGGGTTTGCCCTGTGCCCTCTGGGTGGGGTGGCCTCCCCGCACTCGGCAGCATGGCCAGGCTGGCCAGGGCG TGGGCAGGTGGTGTCCTGTGGCACCTCCATCCTCCTGCCCAGCCGGCTGTGTCACACTCATCTTTTTAAGGTCAGGTTGGTTCCTGGCAA AAATGTACCTCCAGGGGCCTCCAAGCATAGGATTTGGAAGACAGGAACGGCACAGGCGTCCAGGAAAGCAGCTGCACTCAGACAATGCCT TCTCCATTACTTGAAGCTTCTTTCTGTTCAGCCATTAAAGAAACTTGACAAAATAGGAACAGGAGATATTTCTCAATTGTAAACCTTTGT GCAGGGACAGTTGGCTTCCAGAGGCTTTCAGCTTTCAGTTATTTGAGAAGTTTGTTTTAGATCCTTAACTAATATTTATGAATTCTCTCA CCCTGTGTAAGTAGCCTGGTGTTCGTTTGTCCAAGTGTACTTACCCTTGAGAACAAGTCTTGCAGTTGCCAGGTGTGTGCAGACGCCTCT CCTGTGAGCGGCATCGCGGGCCCAGTCAGCTGCCCCGGCTCTCATCCTCGTCCTCACTGCCTTGGCTGAGCACTGTTGACGTGAACAGCC ACTGCAACAGGCAGCCCATCCCACTGTCCCCTCTGCCCTGGACTCCGCATGGCCTCCAAAAGCCAGCTTGCCCTCCGGGTGCTGCAGGGG CTTTGCAGGTGGGGAAGGCTCTGGTGGGTGCCTTTGGTGGCTTCCGTGACATCAGCCGTGCTCTGATGCAGGCTTGCTCCCTCGTCATTC TCCCTCGTCATTCTCCCTCATCGTTCTGTGTGCATTTTTCTCTATGTCCTGACCTTTCTTCTTGCACCTAAAAGTGGTGTCTGGGTGCAA ATGTAAGCAGTGGTGGATCCAGAAATATGAGCTTTGTGTAATAAGCTTCTTAAAACAGTCCTTTCTTACACCTGCCCAGGGCCAGACCCT CGGTCTTGGCCTTTTTCAGGAGCTAGGATATCTGCGCCTGGTGAAAATGAAACGAATTCCTGATTTAGGAATTCAGTGTTTCCTCCTCAC TCCAGCTAAGCACTCACTTTTTTTTTTTTTTTTTTTTTTTTTTGATACAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGA TCTCGGCTCACTGCAAGCTCCACCTCCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAATTGGGATTACAGGCATGCGCCACC ATGCCCAGCTAATTTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCTCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACTGC CAGCTCCGCTTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCCAGGACTACAAGCACCCGCCACCACACCTGGCTAATT TTTTTGTATTTTTATTAGAGACAGTGTTTTACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACTTCGTGATCTACTCACCTCGGCCTCC CAAAGTGCTGGGATTACGGGCAAGTTTTTATTAGAGATGGGGTTTCATCATGTTGGTCAGGCTGGTCTTCAACTCCTGACCTCAGGTGAT CCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTGAACTCTCAGTTCTAACGCAGGGATTCAGG AATTGGGCTTTCAGACTCCTTCTGCAGTGTCACAGTCCAGACTTTTTTTAAATGAAGGACACCCCGCAGTGGCTCACAGTGGGTCCCAGG GCTAGCAGGAGCGTGCTGGGGAGCCGGCTCTGTCTTTGTTCGCAGTGGGTCCCGGTGCTGGCAGGAGTGTGCTGGTGAGCCGGCTCTGTC TTTGTAAATCCTTCAGGGGTCCTACGGCTGACTCCACCGGACAGCCCGTCCTGGGCCGTGTTAAGCACCTTTTGTAGAAATCGTATTTTT |
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FusionGenePPI for SLBP_LETM1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SLBP | ERI1, ZNF473, UPF1, CDK4, CDK6, GSTM3, HIST1H2BG, TACC3, FEM1A, FEM1B, FEM1C, CUL2, NCBP1, CTIF, CCNF, CCNA2, DCAF11, CUL4A, SKP1, CDK1, CDK2, EIF4G1, ZCCHC6, MIF4GD, CSNK2A1, CSNK2A2, CUL1, P4HA3, ZFC3H1 | LETM1 | ICT1, TBK1, ILF3, C12orf57, SYNCRIP, LATS2, PSMA3, CYP1A1, NTRK1, NDUFA4, COQ9, PTPMT1, C15orf48, PPM1A, USP47, SNRNP27, PCDHGB4, HSD3B2, FGB, MRPS11, LYPD4, RNF19B, ATP6V0D1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SLBP_LETM1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SLBP_LETM1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | LETM1 | C0026827 | Muscle hypotonia | 1 | CTD_human;HPO |
| Tgene | LETM1 | C0036572 | Seizures | 1 | CTD_human;HPO |
| Tgene | LETM1 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Tgene | LETM1 | C1956097 | Wolf-Hirschhorn Syndrome | 1 | CTD_human;ORPHANET |
| Tgene | LETM1 | C2239176 | Liver carcinoma | 1 | CTD_human |
| Tgene | LETM1 | C3714756 | Intellectual Disability | 1 | CTD_human |
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