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Fusion gene ID: 33952 |
FusionGeneSummary for SKAP1_PSMD11 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SKAP1_PSMD11 | Fusion gene ID: 33952 | Hgene | Tgene | Gene symbol | SKAP1 | PSMD11 | Gene ID | 8631 | 5717 |
| Gene name | src kinase associated phosphoprotein 1 | proteasome 26S subunit, non-ATPase 11 | |
| Synonyms | HEL-S-81p|SCAP1|SKAP55 | Rpn6|S9|p44.5 | |
| Cytomap | 17q21.32 | 17q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | src kinase-associated phosphoprotein 1SKAP-55epididymis secretory sperm binding protein Li 81ppp55src family-associated phosphoprotein 1src kinase-associated phosphoprotein of 55 kDa | 26S proteasome non-ATPase regulatory subunit 1126S proteasome regulatory subunit 926S proteasome regulatory subunit RPN626S proteasome regulatory subunit S926S proteasome regulatory subunit p44.5proteasome (prosome, macropain) 26S subunit, non-ATPase | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q86WV1 | O00231 | |
| Ensembl transtripts involved in fusion gene | ENST00000336915, ENST00000584924, | ENST00000261712, ENST00000457654, | |
| Fusion gene scores | * DoF score | 16 X 4 X 7=448 | 9 X 7 X 6=378 |
| # samples | 16 | 9 | |
| ** MAII score | log2(16/448*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/378*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SKAP1 [Title/Abstract] AND PSMD11 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SKAP1 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 11909961 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PAAD | TCGA-XD-AAUI-01A | SKAP1 | chr17 | 46423267 | - | PSMD11 | chr17 | 30773963 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000336915 | ENST00000261712 | SKAP1 | chr17 | 46423267 | - | PSMD11 | chr17 | 30773963 | + |
| In-frame | ENST00000336915 | ENST00000457654 | SKAP1 | chr17 | 46423267 | - | PSMD11 | chr17 | 30773963 | + |
| In-frame | ENST00000584924 | ENST00000261712 | SKAP1 | chr17 | 46423267 | - | PSMD11 | chr17 | 30773963 | + |
| In-frame | ENST00000584924 | ENST00000457654 | SKAP1 | chr17 | 46423267 | - | PSMD11 | chr17 | 30773963 | + |
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FusionProtFeatures for SKAP1_PSMD11 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SKAP1 | PSMD11 |
| Positively regulates T-cell receptor signaling byenhancing the MAP kinase pathway. Required for optimal conjugationbetween T-cells and antigen-presenting cells by promoting theclustering of integrin ITGAL on the surface of T-cells. May beinvolved in high affinity immunoglobulin epsilon receptorsignaling in mast cells. {ECO:0000269|PubMed:10856234,ECO:0000269|PubMed:11909961, ECO:0000269|PubMed:12652296,ECO:0000269|PubMed:15939789, ECO:0000269|PubMed:16980616}. | Component of the 26S proteasome, a multiprotein complexinvolved in the ATP-dependent degradation of ubiquitinatedproteins. This complex plays a key role in the maintenance ofprotein homeostasis by removing misfolded or damaged proteins,which could impair cellular functions, and by removing proteinswhose functions are no longer required. Therefore, the proteasomeparticipates in numerous cellular processes, including cell cycleprogression, apoptosis, or DNA damage repair. In the complex,PSMD11 is required for proteasome assembly. Plays a key role inincreased proteasome activity in embryonic stem cells (ESCs): itshigh expression in ESCs promotes enhanced assembly of the 26Sproteasome, followed by higher proteasome activity.{ECO:0000269|PubMed:1317798, ECO:0000269|PubMed:22972301}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PSMD11 | chr17:46423267 | chr17:30773963 | ENST00000261712 | + | 0 | 14 | 224_392 | 30 | 1160 | Domain | PCI |
| Tgene | >PSMD11 | chr17:46423267 | chr17:30773963 | ENST00000457654 | + | 0 | 13 | 224_392 | 30 | 423 | Domain | PCI |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000336915 | - | 4 | 13 | 220_230 | 93 | 448 | Compositional bias | Note=Poly-Glu |
| Hgene | >SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000584924 | - | 4 | 12 | 220_230 | 93 | 360 | Compositional bias | Note=Poly-Glu |
| Hgene | >SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000336915 | - | 4 | 13 | 107_210 | 93 | 448 | Domain | PH |
| Hgene | >SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000336915 | - | 4 | 13 | 294_355 | 93 | 448 | Domain | SH3 |
| Hgene | >SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000584924 | - | 4 | 12 | 107_210 | 93 | 360 | Domain | PH |
| Hgene | >SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000584924 | - | 4 | 12 | 294_355 | 93 | 360 | Domain | SH3 |
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FusionGeneSequence for SKAP1_PSMD11 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SKAP1_ENST00000336915_chr17_46423267_-_PSMD11_ENST00000261712_chr17_30773963_+_486aa MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQDSSDDNHSGTLGLSLTSDAPFLSDY QDEVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWA KSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQ ATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNR SLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLII >In-frame_SKAP1_ENST00000336915_chr17_46423267_-_PSMD11_ENST00000457654_chr17_30773963_+_486aa MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQDSSDDNHSGTLGLSLTSDAPFLSDY QDEVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWA KSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQ ATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNR SLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLII >In-frame_SKAP1_ENST00000584924_chr17_46423267_-_PSMD11_ENST00000261712_chr17_30773963_+_486aa MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQDSSDDNHSGTLGLSLTSDAPFLSDY QDEVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWA KSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQ ATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNR SLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLII >In-frame_SKAP1_ENST00000584924_chr17_46423267_-_PSMD11_ENST00000457654_chr17_30773963_+_486aa MQAAALPEEIRWLLEDAEEFLAEGLRNENLSAVARDHRDHILRGFQQIKARYYWDFQPQGGDIGQDSSDDNHSGTLGLSLTSDAPFLSDY QDEVKRDIQENDEEAVQVKEQSILELGSLLAKTGQAAELGGLLKYVRPFLNSISKAKAARLVRSLLDLFLDMEAATGQEVELCLECIEWA KSEKRTFLRQALEARLVSLYFDTKRYQEALHLGSQLLRELKKMDDKALLVEVQLLESKTYHALSNLPKARAALTSARTTANAIYCPPKLQ ATLDMQSGIIHAAEEKDWKTAYSYFYEAFEGYDSIDSPKAITSLKYMLLCKIMLNTPEDVQALVSGKLALRYAGRQTEALKCVAQASKNR SLADFEKALTDYRAELRDDPIISTHLAKLYDNLLEQNLIRVIEPFSRVQIEHISSLIKLSKADVERKLSQMILDKKFHGILDQGEGVLII |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SKAP1_ENST00000336915_chr17_46423267_-_PSMD11_ENST00000261712_chr17_30773963_+_1458nt ATGCAGGCCGCCGCCCTCCCTGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAATGAGAACCTC AGCGCTGTTGCAAGGGATCACAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAGCCCCAAGGG GGAGACATTGGACAGGACAGCTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTGTCAGATTAT CAGGATGAGGTGAAGCGTGACATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGATCTCTCCTG GCAAAGACTGGACAAGCTGCAGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAAGCAGCTCGC CTGGTCCGATCTCTTCTTGATCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATCGAATGGGCC AAGTCAGAGAAAAGAACTTTCTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAGGAAGCATTG CATTTGGGTTCTCAGCTGCTGCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGCAAAACATAC CATGCCCTGAGCAACCTGCCGAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCTAAATTGCAG GCCACCTTGGACATGCAGTCGGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAGGCATTTGAG GGTTATGACTCCATCGACAGCCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCAGAAGATGTC CAGGCTTTGGTGAGCGGGAAGCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGCAAGAACAGA TCACTGGCAGATTTTGAAAAGGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCCAAGTTGTAT GATAACTTACTAGAACAGAATCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATCAAACTCTCC AAGGCCGACGTGGAAAGGAAATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTCCTGATTATT TTCGATGAACCCCCAGTAGATAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTCTACAACAAA >In-frame_SKAP1_ENST00000336915_chr17_46423267_-_PSMD11_ENST00000457654_chr17_30773963_+_1458nt ATGCAGGCCGCCGCCCTCCCTGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAATGAGAACCTC AGCGCTGTTGCAAGGGATCACAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAGCCCCAAGGG GGAGACATTGGACAGGACAGCTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTGTCAGATTAT CAGGATGAGGTGAAGCGTGACATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGATCTCTCCTG GCAAAGACTGGACAAGCTGCAGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAAGCAGCTCGC CTGGTCCGATCTCTTCTTGATCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATCGAATGGGCC AAGTCAGAGAAAAGAACTTTCTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAGGAAGCATTG CATTTGGGTTCTCAGCTGCTGCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGCAAAACATAC CATGCCCTGAGCAACCTGCCGAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCTAAATTGCAG GCCACCTTGGACATGCAGTCGGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAGGCATTTGAG GGTTATGACTCCATCGACAGCCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCAGAAGATGTC CAGGCTTTGGTGAGCGGGAAGCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGCAAGAACAGA TCACTGGCAGATTTTGAAAAGGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCCAAGTTGTAT GATAACTTACTAGAACAGAATCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATCAAACTCTCC AAGGCCGACGTGGAAAGGAAATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTCCTGATTATT TTCGATGAACCCCCAGTAGATAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTCTACAACAAA >In-frame_SKAP1_ENST00000584924_chr17_46423267_-_PSMD11_ENST00000261712_chr17_30773963_+_1458nt ATGCAGGCCGCCGCCCTCCCTGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAATGAGAACCTC AGCGCTGTTGCAAGGGATCACAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAGCCCCAAGGG GGAGACATTGGACAGGACAGCTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTGTCAGATTAT CAGGATGAGGTGAAGCGTGACATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGATCTCTCCTG GCAAAGACTGGACAAGCTGCAGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAAGCAGCTCGC CTGGTCCGATCTCTTCTTGATCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATCGAATGGGCC AAGTCAGAGAAAAGAACTTTCTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAGGAAGCATTG CATTTGGGTTCTCAGCTGCTGCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGCAAAACATAC CATGCCCTGAGCAACCTGCCGAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCTAAATTGCAG GCCACCTTGGACATGCAGTCGGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAGGCATTTGAG GGTTATGACTCCATCGACAGCCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCAGAAGATGTC CAGGCTTTGGTGAGCGGGAAGCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGCAAGAACAGA TCACTGGCAGATTTTGAAAAGGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCCAAGTTGTAT GATAACTTACTAGAACAGAATCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATCAAACTCTCC AAGGCCGACGTGGAAAGGAAATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTCCTGATTATT TTCGATGAACCCCCAGTAGATAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTCTACAACAAA >In-frame_SKAP1_ENST00000584924_chr17_46423267_-_PSMD11_ENST00000457654_chr17_30773963_+_1458nt ATGCAGGCCGCCGCCCTCCCTGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAATGAGAACCTC AGCGCTGTTGCAAGGGATCACAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAGCCCCAAGGG GGAGACATTGGACAGGACAGCTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTGTCAGATTAT CAGGATGAGGTGAAGCGTGACATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGATCTCTCCTG GCAAAGACTGGACAAGCTGCAGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAAGCAGCTCGC CTGGTCCGATCTCTTCTTGATCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATCGAATGGGCC AAGTCAGAGAAAAGAACTTTCTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAGGAAGCATTG CATTTGGGTTCTCAGCTGCTGCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGCAAAACATAC CATGCCCTGAGCAACCTGCCGAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCTAAATTGCAG GCCACCTTGGACATGCAGTCGGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAGGCATTTGAG GGTTATGACTCCATCGACAGCCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCAGAAGATGTC CAGGCTTTGGTGAGCGGGAAGCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGCAAGAACAGA TCACTGGCAGATTTTGAAAAGGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCCAAGTTGTAT GATAACTTACTAGAACAGAATCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATCAAACTCTCC AAGGCCGACGTGGAAAGGAAATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTCCTGATTATT TTCGATGAACCCCCAGTAGATAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTCTACAACAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SKAP1_ENST00000336915_chr17_46423267_-_PSMD11_ENST00000261712_chr17_30773963_+_4094nt GTCGCCTTCCAGCCCGTCCGCCTCCCGACCAGGGCCCGCGCCCCGTCCCGCCTCTCTCCCGCCCAGCCAAATGCAGGCCGCCGCCCTCCC TGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAATGAGAACCTCAGCGCTGTTGCAAGGGATCA CAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAGCCCCAAGGGGGAGACATTGGACAGGACAG CTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTGTCAGATTATCAGGATGAGGTGAAGCGTGA CATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGATCTCTCCTGGCAAAGACTGGACAAGCTGC AGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAAGCAGCTCGCCTGGTCCGATCTCTTCTTGA TCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATCGAATGGGCCAAGTCAGAGAAAAGAACTTT CTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAGGAAGCATTGCATTTGGGTTCTCAGCTGCT GCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGCAAAACATACCATGCCCTGAGCAACCTGCC GAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCTAAATTGCAGGCCACCTTGGACATGCAGTC GGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAGGCATTTGAGGGTTATGACTCCATCGACAG CCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCAGAAGATGTCCAGGCTTTGGTGAGCGGGAA GCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGCAAGAACAGATCACTGGCAGATTTTGAAAA GGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCCAAGTTGTATGATAACTTACTAGAACAGAA TCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATCAAACTCTCCAAGGCCGACGTGGAAAGGAA ATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTCCTGATTATTTTCGATGAACCCCCAGTAGA TAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTCTACAACAAAGCCAAGAAACTGACATAGAG TTGGATCTGTAGCGGTCCTTTGGAGAGTGTGTGTGGCGGGAGAGTGAAACCTTGGGGGAAAATGCTAGGAGATTCTTTTTTCTTTTTGTT CTACTTTTCGCTCGGAAAGTTTTTAAATCCTCATTTGGTGCATCTGTATTCCAGCCAATAGGTGTGCCAGTTTTCATGTAATCTTTACTG GCCCAACTTGGGAGTGGGGAAATTGCTTAAAAAAAAAGAAAAAGAAAAAAAAAAAGATTATTCTAAATAAAAGGAAAAAGGCTTACACTA CCTAAAGCTGTGCTCTCTGCCTCCTGGGAGAGGGCCGCAAAGCCAGGCACCCCGCCAACCACTGGGGGTCCTAATCCACCTGCTGGGCAT CACCTCTCCTCCTCCTCAGAATTGGGTGTTTGCTGACCATCAAAAGCAATGACTTTTTATTCTGTTTGTACTGAACCAAAACAAACAACT GTGTATAGACTGCTGTTTTCTTTTTTATTTGAAATGAGGCATTTTGGTGTTCTTTCCCCTACCATACGGCCTGTCTGCCCTTCCCTCCCC ACATTGGCTCCAGCAGAGTAGCCGAAGGTCCTGCCGCCGCCGCCACCACCACCACCACTGCAGCAACAACAGCAGCAGCAGCAGCAGCGC CTGCATAGCTCCACTCTGACCTGTGAAGGAATGGGGATGAGGCCAGGAGCTAGTGTCTACCACGGCCACACAGGGAGCAGTGTGGGCCCT TAGCCCCCAAGGGGCCTGCTATGCATGTGGCTTTTTTTTTTTTTTTAAACACAGTAAACTAGATTAGTCGTCAGTGTTTTAATTGCCCCT CTTCTCCTCTCCTGCATTCCTCTCCTCTCTTCTTTCCTCTCTGTCCCTTCTCTTTCCCCTCTCAACCAGGAGACCATCATGTCTCTCTGC CTTCCTCCTCTCCCCTCCAGGGGAGTCAGGCTGTCTGTGAAAGCCATGAGCTTCTCTCCCTCTCCCACTCCTCCTCTCCTACTTTCAGAT GGATTTATTCCTTTTTTAAACAATGAACATCGGAAATGAGACTGTGGGGTGTGGTTTCTCTCTCTCTTTTTTTTTTAATTTTCTTTGTTG GGTTTTTGAGCAACCTCATGTCCCCTTCCCAGGGAGCTTTTTAATTTACCTCTTAGAACTCAAGTGGATGGGAAGTAGAGCACTATGTGT CAGTATGCTTTGTTTTCTGACACGATTACACAGCGAGGCTTTAATGCCATTTGGGTAGGTGAGCTTCTGCACTTCTGTTGTGCTGAACTG TATTTTCTTCTCTCATCTCCTCTTTGTCTTTTTCTCTTTTCCTCTCCTTCCTGCCTTCTTCTGCTGGCCTCCTTTTCTCTTTCTTTACCT TCCTTGGATTATCCTTCCAGGTTTTCATAATAAATTTATATTTTGTAAAAGGATTTTGTTGTACCAGGTTTTGCATCCTCACTGAATCTG ACTGGCTTTTATTTTCCTCTCCAAAATCAGGTTTTTGTTCTCAACATCTTTCCCCATCATGTCTAGTCACTGTTTTGGTTTTGGCACCAT CAGTATCAAATGTACAAACGGTTCTTGCTAACCAACACCAGGTATATCTGATGTTCAGATGAGTTCCAATAAAAATAATTTTTTTTTTTT TCAAAAGGTGTCTTTTTCTTGAGTGCTGGAGGGCTTCCAAGCAAGTCCAGACAGCTCTGTGTGGCCCCACACTAGTCTAGCTCTCATCTG GCCAAAGCTGTTATCTCATTTGTGTAATGGGAGTCCTTAAGGTAAATTTGGGGTCCAAACTTGGAGGGCTTTGGGGGCAAGAAAGTTGGT GTGTGAGTTCTGAGGTTGGAAATGAGTTCAGGTGTCTTCTTCCAGGGCAGCATGGTCCAGTGAGCACATGTAAGTTTGGGCAGTAGATCC TCTGAGCCTACTTTCTCTTCTACTCAGTGAGGATGCTGCTTCCTTGGCAGGTGATTGTGATGTGAAGCTTAGTAAGTCATAGACGTGCAG GTGTCTGGAGAGTCCTGACATGCAGTTGTGGTTTCGTTTCCTTTTGGAATCTTCAAAGGCAGCGATTTTCATATTGCCTCACACCCTGGC GGGGGCGGGGGGCTCTGGGACCACTGGGGGACCTGCTAAATCCTCTTCAGTCTGAGCAGTTCAGCCATTGTCAGTTTTAGTATTGTGTCT CTGTATTTCACTTGCAGAAAGAGCTTTGCTTCTATAAAGGACTTTAAAAAGTACTCCAAAGAGATCTAGTTTTGGAGTAGAGGGGAGATG TTTTCTCAAACTTAGGGCAGTCCTGAGATGCTCAGGCAGTAGCCCTTTTCTCAGTTCCCTTTGCGGGTCTTGGTCAGATGATGCCCTCTA GACCCGTGCTGTCCAATATGTAGCCGCTAGCCATGTGCAGCTGTCAGGCCCTTGCAACGTGGCTGGTTCGAGCTGTGATACACTGCAAGT GTAAACACAAACCAGACTTCGAAGGCTTAGTATGATAACAAAAGAAAAGGAGTGTAAAATATGTCAATAACTTTTTTATATATGTGTTGA >In-frame_SKAP1_ENST00000336915_chr17_46423267_-_PSMD11_ENST00000457654_chr17_30773963_+_2368nt GTCGCCTTCCAGCCCGTCCGCCTCCCGACCAGGGCCCGCGCCCCGTCCCGCCTCTCTCCCGCCCAGCCAAATGCAGGCCGCCGCCCTCCC TGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAATGAGAACCTCAGCGCTGTTGCAAGGGATCA CAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAGCCCCAAGGGGGAGACATTGGACAGGACAG CTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTGTCAGATTATCAGGATGAGGTGAAGCGTGA CATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGATCTCTCCTGGCAAAGACTGGACAAGCTGC AGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAAGCAGCTCGCCTGGTCCGATCTCTTCTTGA TCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATCGAATGGGCCAAGTCAGAGAAAAGAACTTT CTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAGGAAGCATTGCATTTGGGTTCTCAGCTGCT GCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGCAAAACATACCATGCCCTGAGCAACCTGCC GAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCTAAATTGCAGGCCACCTTGGACATGCAGTC GGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAGGCATTTGAGGGTTATGACTCCATCGACAG CCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCAGAAGATGTCCAGGCTTTGGTGAGCGGGAA GCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGCAAGAACAGATCACTGGCAGATTTTGAAAA GGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCCAAGTTGTATGATAACTTACTAGAACAGAA TCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATCAAACTCTCCAAGGCCGACGTGGAAAGGAA ATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTCCTGATTATTTTCGATGAACCCCCAGTAGA TAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTCTACAACAAAGCCAAGAAACTGACATAGGT GAGTGCTGGCTTCAGGACCCCAGGGCTGGGCAGCTCTGTCTTCTGCGTGTCGAGACTGAAAACCTCCTCCTGGTGTCCTCATGGCTTCCT GATTGACACTGCTCTGTCTTCTCTTGCAGAGTTGGATCTGTAGCGGTCCTTTGGAGAGTGTGTGTGGCGGGAGAGTGAAACCTTGGGGGA AAATGCTAGGAGATTCTTTTTTCTTTTTGTTCTACTTTTCGCTCGGAAAGTTTTTAAATCCTCATTTGGTGCATCTGTATTCCAGCCAAT AGGTGTGCCAGTTTTCATGTAATCTTTACTGGCCCAACTTGGGAGTGGGGAAATTGCTTAAAAAAAAAGAAAAAGAAAAAAAAAAAGATT ATTCTAAATAAAAGGAAAAAGGCTTACACTACCTAAAGCTGTGCTCTCTGCCTCCTGGGAGAGGGCCGCAAAGCCAGGCACCCCGCCAAC CACTGGGGGTCCTAATCCACCTGCTGGGCATCACCTCTCCTCCTCCTCAGAATTGGGTGTTTGCTGACCATCAAAAGCAATGACTTTTTA TTCTGTTTGTACTGAACCAAAACAAACAACTGTGTATAGACTGCTGTTTTCTTTTTTATTTGAAATGAGGCATTTTGGTGTTCTTTCCCC TACCATACGGCCTGTCTGCCCTTCCCTCCCCACATTGGCTCCAGCAGAGTAGCCGAAGGTCCTGCCGCCGCCGCCACCACCACCACCACT GCAGCAACAACAGCAGCAGCAGCAGCAGCGCCTGCATAGCTCCACTCTGACCTGTGAAGGAATGGGGATGAGGCCAGGAGCTAGTGTCTA >In-frame_SKAP1_ENST00000584924_chr17_46423267_-_PSMD11_ENST00000261712_chr17_30773963_+_4123nt GAGGTACAGGTGCCTCGCGGTGCAGCCGGGTCGCCTTCCAGCCCGTCCGCCTCCCGACCAGGGCCCGCGCCCCGTCCCGCCTCTCTCCCG CCCAGCCAAATGCAGGCCGCCGCCCTCCCTGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAAT GAGAACCTCAGCGCTGTTGCAAGGGATCACAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAG CCCCAAGGGGGAGACATTGGACAGGACAGCTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTG TCAGATTATCAGGATGAGGTGAAGCGTGACATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGA TCTCTCCTGGCAAAGACTGGACAAGCTGCAGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAA GCAGCTCGCCTGGTCCGATCTCTTCTTGATCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATC GAATGGGCCAAGTCAGAGAAAAGAACTTTCTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAG GAAGCATTGCATTTGGGTTCTCAGCTGCTGCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGC AAAACATACCATGCCCTGAGCAACCTGCCGAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCT AAATTGCAGGCCACCTTGGACATGCAGTCGGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAG GCATTTGAGGGTTATGACTCCATCGACAGCCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCA GAAGATGTCCAGGCTTTGGTGAGCGGGAAGCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGC AAGAACAGATCACTGGCAGATTTTGAAAAGGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCC AAGTTGTATGATAACTTACTAGAACAGAATCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATC AAACTCTCCAAGGCCGACGTGGAAAGGAAATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTC CTGATTATTTTCGATGAACCCCCAGTAGATAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTC TACAACAAAGCCAAGAAACTGACATAGAGTTGGATCTGTAGCGGTCCTTTGGAGAGTGTGTGTGGCGGGAGAGTGAAACCTTGGGGGAAA ATGCTAGGAGATTCTTTTTTCTTTTTGTTCTACTTTTCGCTCGGAAAGTTTTTAAATCCTCATTTGGTGCATCTGTATTCCAGCCAATAG GTGTGCCAGTTTTCATGTAATCTTTACTGGCCCAACTTGGGAGTGGGGAAATTGCTTAAAAAAAAAGAAAAAGAAAAAAAAAAAGATTAT TCTAAATAAAAGGAAAAAGGCTTACACTACCTAAAGCTGTGCTCTCTGCCTCCTGGGAGAGGGCCGCAAAGCCAGGCACCCCGCCAACCA CTGGGGGTCCTAATCCACCTGCTGGGCATCACCTCTCCTCCTCCTCAGAATTGGGTGTTTGCTGACCATCAAAAGCAATGACTTTTTATT CTGTTTGTACTGAACCAAAACAAACAACTGTGTATAGACTGCTGTTTTCTTTTTTATTTGAAATGAGGCATTTTGGTGTTCTTTCCCCTA CCATACGGCCTGTCTGCCCTTCCCTCCCCACATTGGCTCCAGCAGAGTAGCCGAAGGTCCTGCCGCCGCCGCCACCACCACCACCACTGC AGCAACAACAGCAGCAGCAGCAGCAGCGCCTGCATAGCTCCACTCTGACCTGTGAAGGAATGGGGATGAGGCCAGGAGCTAGTGTCTACC ACGGCCACACAGGGAGCAGTGTGGGCCCTTAGCCCCCAAGGGGCCTGCTATGCATGTGGCTTTTTTTTTTTTTTTAAACACAGTAAACTA GATTAGTCGTCAGTGTTTTAATTGCCCCTCTTCTCCTCTCCTGCATTCCTCTCCTCTCTTCTTTCCTCTCTGTCCCTTCTCTTTCCCCTC TCAACCAGGAGACCATCATGTCTCTCTGCCTTCCTCCTCTCCCCTCCAGGGGAGTCAGGCTGTCTGTGAAAGCCATGAGCTTCTCTCCCT CTCCCACTCCTCCTCTCCTACTTTCAGATGGATTTATTCCTTTTTTAAACAATGAACATCGGAAATGAGACTGTGGGGTGTGGTTTCTCT CTCTCTTTTTTTTTTAATTTTCTTTGTTGGGTTTTTGAGCAACCTCATGTCCCCTTCCCAGGGAGCTTTTTAATTTACCTCTTAGAACTC AAGTGGATGGGAAGTAGAGCACTATGTGTCAGTATGCTTTGTTTTCTGACACGATTACACAGCGAGGCTTTAATGCCATTTGGGTAGGTG AGCTTCTGCACTTCTGTTGTGCTGAACTGTATTTTCTTCTCTCATCTCCTCTTTGTCTTTTTCTCTTTTCCTCTCCTTCCTGCCTTCTTC TGCTGGCCTCCTTTTCTCTTTCTTTACCTTCCTTGGATTATCCTTCCAGGTTTTCATAATAAATTTATATTTTGTAAAAGGATTTTGTTG TACCAGGTTTTGCATCCTCACTGAATCTGACTGGCTTTTATTTTCCTCTCCAAAATCAGGTTTTTGTTCTCAACATCTTTCCCCATCATG TCTAGTCACTGTTTTGGTTTTGGCACCATCAGTATCAAATGTACAAACGGTTCTTGCTAACCAACACCAGGTATATCTGATGTTCAGATG AGTTCCAATAAAAATAATTTTTTTTTTTTTCAAAAGGTGTCTTTTTCTTGAGTGCTGGAGGGCTTCCAAGCAAGTCCAGACAGCTCTGTG TGGCCCCACACTAGTCTAGCTCTCATCTGGCCAAAGCTGTTATCTCATTTGTGTAATGGGAGTCCTTAAGGTAAATTTGGGGTCCAAACT TGGAGGGCTTTGGGGGCAAGAAAGTTGGTGTGTGAGTTCTGAGGTTGGAAATGAGTTCAGGTGTCTTCTTCCAGGGCAGCATGGTCCAGT GAGCACATGTAAGTTTGGGCAGTAGATCCTCTGAGCCTACTTTCTCTTCTACTCAGTGAGGATGCTGCTTCCTTGGCAGGTGATTGTGAT GTGAAGCTTAGTAAGTCATAGACGTGCAGGTGTCTGGAGAGTCCTGACATGCAGTTGTGGTTTCGTTTCCTTTTGGAATCTTCAAAGGCA GCGATTTTCATATTGCCTCACACCCTGGCGGGGGCGGGGGGCTCTGGGACCACTGGGGGACCTGCTAAATCCTCTTCAGTCTGAGCAGTT CAGCCATTGTCAGTTTTAGTATTGTGTCTCTGTATTTCACTTGCAGAAAGAGCTTTGCTTCTATAAAGGACTTTAAAAAGTACTCCAAAG AGATCTAGTTTTGGAGTAGAGGGGAGATGTTTTCTCAAACTTAGGGCAGTCCTGAGATGCTCAGGCAGTAGCCCTTTTCTCAGTTCCCTT TGCGGGTCTTGGTCAGATGATGCCCTCTAGACCCGTGCTGTCCAATATGTAGCCGCTAGCCATGTGCAGCTGTCAGGCCCTTGCAACGTG GCTGGTTCGAGCTGTGATACACTGCAAGTGTAAACACAAACCAGACTTCGAAGGCTTAGTATGATAACAAAAGAAAAGGAGTGTAAAATA >In-frame_SKAP1_ENST00000584924_chr17_46423267_-_PSMD11_ENST00000457654_chr17_30773963_+_2397nt GAGGTACAGGTGCCTCGCGGTGCAGCCGGGTCGCCTTCCAGCCCGTCCGCCTCCCGACCAGGGCCCGCGCCCCGTCCCGCCTCTCTCCCG CCCAGCCAAATGCAGGCCGCCGCCCTCCCTGAGGAGATCCGTTGGCTCCTGGAAGATGCTGAAGAGTTTCTGGCAGAAGGTTTGCGGAAT GAGAACCTCAGCGCTGTTGCAAGGGATCACAGAGACCATATTCTACGGGGCTTTCAGCAAATCAAAGCCAGGTACTATTGGGATTTTCAG CCCCAAGGGGGAGACATTGGACAGGACAGCTCTGATGATAATCACAGCGGGACTCTTGGCCTGTCCCTCACATCCGATGCACCCTTTTTG TCAGATTATCAGGATGAGGTGAAGCGTGACATTCAGGAAAACGATGAAGAGGCAGTGCAAGTCAAAGAGCAGAGCATCCTGGAACTGGGA TCTCTCCTGGCAAAGACTGGACAAGCTGCAGAGCTTGGAGGACTCCTGAAGTATGTACGACCCTTCTTGAATTCCATCAGCAAGGCTAAA GCAGCTCGCCTGGTCCGATCTCTTCTTGATCTGTTTCTTGATATGGAAGCAGCTACAGGGCAGGAGGTCGAGCTGTGTTTAGAGTGCATC GAATGGGCCAAGTCAGAGAAAAGAACTTTCTTACGCCAAGCTTTGGAGGCAAGACTGGTGTCTTTGTACTTTGATACCAAGAGGTACCAG GAAGCATTGCATTTGGGTTCTCAGCTGCTGCGGGAGTTGAAAAAGATGGACGACAAAGCTCTTTTGGTGGAAGTACAGCTTTTAGAAAGC AAAACATACCATGCCCTGAGCAACCTGCCGAAAGCCCGAGCTGCCTTAACTTCTGCTCGAACCACAGCAAATGCCATCTACTGCCCCCCT AAATTGCAGGCCACCTTGGACATGCAGTCGGGTATTATCCATGCAGCAGAAGAGAAGGACTGGAAAACTGCGTACTCATACTTCTATGAG GCATTTGAGGGTTATGACTCCATCGACAGCCCCAAGGCCATCACATCTCTGAAGTACATGTTGCTGTGCAAAATCATGCTCAACACCCCA GAAGATGTCCAGGCTTTGGTGAGCGGGAAGCTTGCACTTCGGTATGCAGGGAGGCAGACAGAAGCATTAAAATGCGTGGCTCAGGCTAGC AAGAACAGATCACTGGCAGATTTTGAAAAGGCTCTGACAGATTACCGGGCAGAGCTCCGGGATGACCCAATCATCAGCACACACTTGGCC AAGTTGTATGATAACTTACTAGAACAGAATCTGATCCGAGTCATTGAGCCTTTTTCCAGAGTACAGATTGAACACATATCTAGTCTCATC AAACTCTCCAAGGCCGACGTGGAAAGGAAATTATCACAGATGATTCTTGACAAGAAATTTCATGGGATTTTGGACCAGGGGGAGGGTGTC CTGATTATTTTCGATGAACCCCCAGTAGATAAAACTTACGAAGCTGCTCTGGAAACAATTCAGAACATGAGCAAAGTAGTGGATTCCCTC TACAACAAAGCCAAGAAACTGACATAGGTGAGTGCTGGCTTCAGGACCCCAGGGCTGGGCAGCTCTGTCTTCTGCGTGTCGAGACTGAAA ACCTCCTCCTGGTGTCCTCATGGCTTCCTGATTGACACTGCTCTGTCTTCTCTTGCAGAGTTGGATCTGTAGCGGTCCTTTGGAGAGTGT GTGTGGCGGGAGAGTGAAACCTTGGGGGAAAATGCTAGGAGATTCTTTTTTCTTTTTGTTCTACTTTTCGCTCGGAAAGTTTTTAAATCC TCATTTGGTGCATCTGTATTCCAGCCAATAGGTGTGCCAGTTTTCATGTAATCTTTACTGGCCCAACTTGGGAGTGGGGAAATTGCTTAA AAAAAAAGAAAAAGAAAAAAAAAAAGATTATTCTAAATAAAAGGAAAAAGGCTTACACTACCTAAAGCTGTGCTCTCTGCCTCCTGGGAG AGGGCCGCAAAGCCAGGCACCCCGCCAACCACTGGGGGTCCTAATCCACCTGCTGGGCATCACCTCTCCTCCTCCTCAGAATTGGGTGTT TGCTGACCATCAAAAGCAATGACTTTTTATTCTGTTTGTACTGAACCAAAACAAACAACTGTGTATAGACTGCTGTTTTCTTTTTTATTT GAAATGAGGCATTTTGGTGTTCTTTCCCCTACCATACGGCCTGTCTGCCCTTCCCTCCCCACATTGGCTCCAGCAGAGTAGCCGAAGGTC CTGCCGCCGCCGCCACCACCACCACCACTGCAGCAACAACAGCAGCAGCAGCAGCAGCGCCTGCATAGCTCCACTCTGACCTGTGAAGGA |
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FusionGenePPI for SKAP1_PSMD11 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SKAP1 | PTPRC, FYB, SRC, LYN, FYN, LCK, SKAP1, GRB2, APP, BLCAP, SH2D4A, PRAM1, FAM102A, AP3M1, MYO9B, MYO9A, POLR1B, LOC81691, EML3, WRN, ASPM, JPH1, POLR1A, POLR3A, RECQL4, HPS3, ZNF324, FAM208A, UXT, NCAPD3, MYCBP2, CUL2, PIP5K1A, NEK1, PLEKHH3, PHLDB3, PIK3C3, SEC63, SKAP2, GTF3C1, URI1, PIK3R2, PIK3R3, POLRMT, PLD2, UCKL1, PRR14L, KSR1, ZNHIT6, PDRG1, SETX, NEFL, ALMS1, APPBP2, DDX11L8, UTP15, SENP5, NCAPH2, PAX3, TBL2, ZNHIT2, ZNF644, SUGCT, PKN3, TTF2, PPHLN1, NPHP4, MTMR1, PKN2, C21orf2, POLA1, POLR3B, POLR2L, CCP110, SETD5, ELP3, DOCK7, USP54, POLR1E, TRMT44, POLR1D, EXPH5, NEK4, ATXN2, SBF1, GTPBP6, TRMT1, CD3EAP, PER1, SUPT6H, MCM8, RTEL1, TIGD5, PUSL1, KLHDC3, DYNLL2, MAP7D1 | PSMD11 | PSMD13, PSMD10, PSMD6, PAAF1, PSMC4, GDF9, CCSER2, CCDC90B, IGSF21, PTPRK, COPS6, HAP1, SETDB1, ZHX1, MED31, EEF1G, GAPDH, PTN, LRIF1, TLE1, TP53, TUBB2A, UNC119, ZBTB16, BRD7, CRMP1, RBM48, EEF1A1, PSMD14, PSMD7, UCHL5, USP14, USP15, USP20, SLX1B, NFKB2, UBC, HDAC5, INSIG2, SHFM1, RAD23A, PRKAB2, PRKAA2, PRKAA1, FKBP8, FBXO25, PSMA2, CDK2, USP4, GRK5, GRB2, APP, PSMC5, PSMC6, PSMC1, PSMC3, PSMC2, PSMD12, PSMD1, PSMD2, PSMD3, PSMD8, PSMD4, PSMA5, PSMA7, PSMB1, PSMA6, PSMA3, PSMB7, PSMA1, PSMB2, PSMB3, PSMB5, PSMA4, PSMB4, PSME3, PUS1, LRRK2, FN1, VCAM1, NOS2, SMAD3, SMAD4, SMAD2, SMAD1, SMAD5, CFTR, PARK2, PRMT6, RNF11, ADRM1, KIAA0368, KCMF1, RPS15A, RPS21, RPS8, ASB11, HUWE1, CUL7, CCDC74B, CCDC92, PSMB9, COPS3, COX5A, DCTN1, DNAJA2, MCFD2, MTCH1, NHP2L1, NLRP9, POLE, PSMB6, PSMB8, DNAJA1, DNAJA4, IKBKAP, PSMD5, PSMD9, NTRK1, HERC2, FAN1, RNF168, SUCO, CRY1, CRY2, PRKACA, MID2, SNW1, CDC5L, RC3H1, DERL1, UBLCP1, KDELR1, ODF1, ATG9A, ZFYVE27, NALCN, SLCO6A1, SLC17A2, TMC7, CYLD, DLD, HSD17B10, SOD1, BRCA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000336915 | - | 4 | 13 | 290_295 | 93 | 448 | FYB1 |
| Hgene | SKAP1 | chr17:46423267 | chr17:30773963 | ENST00000584924 | - | 4 | 12 | 290_295 | 93 | 360 | FYB1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SKAP1_PSMD11 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SKAP1_PSMD11 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SKAP1 | C0919267 | ovarian neoplasm | 1 | CTD_human |
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