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Fusion gene ID: 33797 |
FusionGeneSummary for SHMT2_SLC26A10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SHMT2_SLC26A10 | Fusion gene ID: 33797 | Hgene | Tgene | Gene symbol | SHMT2 | SLC26A10 | Gene ID | 6472 | 65012 |
| Gene name | serine hydroxymethyltransferase 2 | solute carrier family 26 member 10 | |
| Synonyms | GLYA|HEL-S-51e|SHMT | - | |
| Cytomap | 12q13.3 | 12q13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine hydroxymethyltransferase, mitochondrialGLY A+epididymis secretory sperm binding protein Li 51eglycine auxotroph A, human complement for hamsterglycine hydroxymethyltransferaseserine aldolaseserine hydroxymethylaseserine hydroxymethyltransfer | solute carrier family 26 member 10 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | P34897 | Q8NG04 | |
| Ensembl transtripts involved in fusion gene | ENST00000328923, ENST00000554600, ENST00000557487, ENST00000414700, ENST00000553474, ENST00000449049, ENST00000393827, | ENST00000320442, ENST00000379218, ENST00000490243, | |
| Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 4 X 3 X 2=24 |
| # samples | 2 | 3 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(3/24*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SHMT2 [Title/Abstract] AND SLC26A10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SHMT2 | GO:0006544 | glycine metabolic process | 25619277|29180469 |
| Hgene | SHMT2 | GO:0006563 | L-serine metabolic process | 25619277|29180469 |
| Hgene | SHMT2 | GO:0006730 | one-carbon metabolic process | 11516159|29180469|29364879|29452640 |
| Hgene | SHMT2 | GO:0034340 | response to type I interferon | 24075985 |
| Hgene | SHMT2 | GO:0046653 | tetrahydrofolate metabolic process | 24075985|25619277 |
| Hgene | SHMT2 | GO:0051262 | protein tetramerization | 25619277 |
| Hgene | SHMT2 | GO:0051289 | protein homotetramerization | 29180469 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | GBM | TCGA-28-5207-01A | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000328923 | ENST00000320442 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| In-frame | ENST00000328923 | ENST00000379218 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| 5CDS-3UTR | ENST00000328923 | ENST00000490243 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| intron-3CDS | ENST00000554600 | ENST00000320442 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| intron-3CDS | ENST00000554600 | ENST00000379218 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| intron-3UTR | ENST00000554600 | ENST00000490243 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| Frame-shift | ENST00000557487 | ENST00000320442 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| In-frame | ENST00000557487 | ENST00000379218 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| 5CDS-3UTR | ENST00000557487 | ENST00000490243 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| Frame-shift | ENST00000414700 | ENST00000320442 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| In-frame | ENST00000414700 | ENST00000379218 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| 5CDS-3UTR | ENST00000414700 | ENST00000490243 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| Frame-shift | ENST00000553474 | ENST00000320442 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| In-frame | ENST00000553474 | ENST00000379218 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| 5CDS-3UTR | ENST00000553474 | ENST00000490243 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| Frame-shift | ENST00000449049 | ENST00000320442 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| In-frame | ENST00000449049 | ENST00000379218 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| 5CDS-3UTR | ENST00000449049 | ENST00000490243 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| Frame-shift | ENST00000393827 | ENST00000320442 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| In-frame | ENST00000393827 | ENST00000379218 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
| 5CDS-3UTR | ENST00000393827 | ENST00000490243 | SHMT2 | chr12 | 57627893 | + | SLC26A10 | chr12 | 58018649 | + |
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FusionProtFeatures for SHMT2_SLC26A10 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SHMT2 | SLC26A10 |
| Catalyzes the cleavage of serine to glycine accompaniedwith the production of 5,10-methylenetetrahydrofolate, anessential intermediate for purine biosynthesis (PubMed:24075985,PubMed:29364879, PubMed:25619277). Serine provides the majorsource of folate one-carbon in cells by catalyzing the transfer ofone carbon from serine to tetrahydrofolate (PubMed:25619277).Contributes to the de novo mitochondrial thymidylate biosynthesispathway via its role in glycine and tetrahydrofolate metabolism:thymidylate biosynthesis is required to prevent uracilaccumulation in mtDNA (PubMed:21876188). Also required formitochondrial translation by producing 5,10-methylenetetrahydrofolate; 5,10-methylenetetrahydrofolateproviding methyl donors to produce the taurinomethyluridine baseat the wobble position of some mitochondrial tRNAs(PubMed:29452640, PubMed:29364879). Associates with mitochondrialDNA (PubMed:18063578). In addition to its role in mitochondia,also plays a role in the deubiquitination of target proteins ascomponent of the BRISC complex: required for IFNAR1deubiquitination by the BRISC complex (PubMed:24075985).{ECO:0000269|PubMed:18063578, ECO:0000269|PubMed:21876188,ECO:0000269|PubMed:24075985, ECO:0000269|PubMed:25619277,ECO:0000269|PubMed:29364879, ECO:0000269|PubMed:29452640}. | Chloride/bicarbonate exchanger. {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for SHMT2_SLC26A10 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SHMT2_ENST00000328923_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_472aa MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGS CLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV KRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKH ADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARA MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDE >In-frame_SHMT2_ENST00000557487_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_462aa MLYFSLFWAARPLQRCGQLVRMAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGS CLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDV KRISATSIFFESMPYKLNLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHK TLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGY SLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKS >In-frame_SHMT2_ENST00000414700_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_451aa MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEV VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAPPGPGALH >In-frame_SHMT2_ENST00000553474_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_451aa MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEV VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAPPGPGALH >In-frame_SHMT2_ENST00000449049_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_451aa MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEV VDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIF YRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAPPGPGALH >In-frame_SHMT2_ENST00000393827_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_376aa MGEQRWWMKLSCCASAGPWKPLTWILHSGESMSSPTPGPQPTWPSTQPFCNLTTGSWGWTCPMGAISPTATCLTSSGYQPRPSSSSLCPI SSTALAVCVSVQPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTT TTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALL ERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SHMT2_ENST00000328923_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_1418nt ATGCTGTACTTCTCTTTGTTTTGGGCGGCTCGGCCTCTGCAGAGATGTGGGCAGCTGGTCAGGATGGCCATTCGGGCTCAGCACAGCAAC GCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGACAGTGATCCTGAGATGTGGGAGTTGCTG CAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGCCGAGCTGCGCTGGAGGCCCTGGGGTCC TGTCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCCAG CGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCGTC TACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCATCTCACCCACGGCTACATGTCTGACGTC AAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACCCCAAAACTGGCCTCATTGACTACAACCAGCTGGCA CTGACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCTATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTG TGTGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCCTGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCAC GCGGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGAC CCCAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTGCCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCAT GCCATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCC ATGGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTGACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGC CTGGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCACA CCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAGGATGACTTCCGGAGAGTTGTGGACTTTATAGATGAA >In-frame_SHMT2_ENST00000557487_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_1388nt ATGCTGTACTTCTCTTTGTTTTGGGCGGCTCGGCCTCTGCAGAGATGTGGGCAGCTGGTCAGGATGGCCATTCGGGCTCAGCACAGCAAC GCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGACAGTGATCCTGAGATGTGGGAGTTGCTG CAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGCCGAGCTGCGCTGGAGGCCCTGGGGTCC TGTCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCCAG CGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCGTC TACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCATCTCACCCACGGCTACATGTCTGACGTC AAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTC ATCATAGCTGGCACCAGCGCCTATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCA GACATGGCCCACATCAGTGGCCTGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAG ACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACA TTTGAGGACCGAATCAACTTTGCCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAG CAGGCCTGCACCCCCATGTTCCGGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTAC TCACTGGTATCAGGTGGTACTGACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTA GAGCTTGTATCCATCACTGCCAACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCC TTAACTTCTCGACAGTTCCGTGAGGATGACTTCCGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGC >In-frame_SHMT2_ENST00000414700_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_1355nt ATGGCCATTCGGGCTCAGCACAGCAACGCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGAC AGTGATCCTGAGATGTGGGAGTTGCTGCAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGC CGAGCTGCGCTGGAGGCCCTGGGGTCCTGTCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTG GTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTAC TCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCAT CTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACCCCAAAACT GGCCTCATTGACTACAACCAGCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCTATGCTCGCCTC ATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCCTGGTGGCTGCC AAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTC TACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTGCCGTGTTCCCA TCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGGGAGTACTCC CTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTGACAACCACCTG GTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAACAAGAACACC TGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAGGATGACTTC CGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCTCCTCCAGGTCCCGGGGCTCTGCAT >In-frame_SHMT2_ENST00000553474_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_1355nt ATGGCCATTCGGGCTCAGCACAGCAACGCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGAC AGTGATCCTGAGATGTGGGAGTTGCTGCAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGC CGAGCTGCGCTGGAGGCCCTGGGGTCCTGTCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTG GTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTAC TCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCAT CTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACCCCAAAACT GGCCTCATTGACTACAACCAGCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCTATGCTCGCCTC ATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCCTGGTGGCTGCC AAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTC TACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTGCCGTGTTCCCA TCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGGGAGTACTCC CTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTGACAACCACCTG GTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAACAAGAACACC TGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAGGATGACTTC CGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCTCCTCCAGGTCCCGGGGCTCTGCAT >In-frame_SHMT2_ENST00000449049_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_1355nt ATGGCCATTCGGGCTCAGCACAGCAACGCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGAC AGTGATCCTGAGATGTGGGAGTTGCTGCAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGC CGAGCTGCGCTGGAGGCCCTGGGGTCCTGTCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTG GTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTAC TCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCAT CTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACCCCAAAACT GGCCTCATTGACTACAACCAGCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCTATGCTCGCCTC ATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCCTGGTGGCTGCC AAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTC TACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTGCCGTGTTCCCA TCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGGGAGTACTCC CTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTGACAACCACCTG GTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAACAAGAACACC TGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAGGATGACTTC CGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCTCCTCCAGGTCCCGGGGCTCTGCAT >In-frame_SHMT2_ENST00000393827_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_1130nt ATGGGGGAGCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAG TCAATGTCCAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACC TGCCCGATGGGGGCCATCTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATA AGCTCAACGGCTTTAGCTGTTTGTGTGTCTGTCCAGCCCAAAACTGGCCTCATTGACTACAACCAGCTGGCACTGACTGCTCGACTTTTC CGGCCACGGCTCATCATAGCTGGCACCAGCGCCTATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCA CACCTGCTGGCAGACATGGCCCACATCAGTGGCCTGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACC ACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAG ATCCCTTACACATTTGAGGACCGAATCAACTTTGCCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCT GTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTA GAGCGAGGCTACTCACTGGTATCAGGTGGTACTGACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCT GAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTT GGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAGGATGACTTCCGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SHMT2_ENST00000328923_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_2709nt ACGGTGCTTTCCAGTGTTCCATAGCTCTTTATCTTGTGTGGGGGTCTAGATCTCCTGGAGTCTAATAATGCTAGCTAGATATTCAGTAGG CACCCTATAAACGTTTGTCTTGACAACAAGCAGAGAGAAAACCCTGAAAAGCTTCAAGATAGTAAGGAGAGGGGGCGGCACTGGACCTCT GTTTTTGTTTTTTGTTTTTTTCCCCCCAGGCAAGGGCCTCTAACCCTGGGGCTACAGACGGGAATCATAAAGAAAAAAGCGGTGAGTGGG CGAACTACAATTCCCAAAAGGCCACAAAGGGGCCACCACTACGCATGCGTAGATCCCTCCCGTTAGCTTTGGCGCCTCAGCGAGCTCTTC TCGCGCATGCGTTCTCCGAACGGTCTTCTTCCGACAGCTTGCTGCCCTAGACCAGAGTTGGTGGCTGGACCTCCTGCGACTTCCGAGTTG CGATGCTGTACTTCTCTTTGTTTTGGGCGGCTCGGCCTCTGCAGAGATGTGGGCAGCTGGTCAGGATGGCCATTCGGGCTCAGCACAGCA ACGCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGACAGTGATCCTGAGATGTGGGAGTTGC TGCAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGCCGAGCTGCGCTGGAGGCCCTGGGGT CCTGTCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCC AGCGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCG TCTACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCATCTCACCCACGGCTACATGTCTGACG TCAAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACCCCAAAACTGGCCTCATTGACTACAACCAGCTGG CACTGACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCTATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGG TGTGTGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCCTGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGC ACGCGGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGG ACCCCAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTGCCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATC ATGCCATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGG CCATGGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTGACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGG GCCTGGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCA CACCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAGGATGACTTCCGGAGAGTTGTGGACTTTATAGATG AAGGGGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCTCCTCCAGGTCCCGGGGCTCTGCATCCTGAGCTATCCAACACCACTGTAC TTTGGGACCCGTGGGCAGTTTCGCTGCAACCTGGAGTGGCACCTGGGGCTCGGAGAAGGAGAAAAGGAGACTTCAAAGCCAGATGGCCCA ATGGTTGCAGTTGCTGAGCCTGTCAGGGTGGTGGTCCTAGACTTCAGTGGTGTCACCTTTGCAGATGCTGCTGGGGCCAGAGAAGTGGTG CAGGTGAGGGAGAGGCTGGCCAGCCGATGTCGAGATGCTAGGATCCGCCTCCTCCTGGCTCAGTGTAATGCCTTGGTGCAGGGGACACTG ACCCGGGTAGGACTCCTGGACAGGGTGACTCCAGATCAGCTGTTTGTGAGTGTGCAGGATGCAGCTGCTTATGCCCTGGGGAGCCTGTTA AGGGGCAGTAGCACCAGGAGCGGGAGCCAGGAGGCACTGGGCTGCGGCAAGTGAGGCAGGGGTAAGTGGCTGGAGACCCAGGGAGAGGGG TTTGGGAAAGGGTCTGAGGAAGATCAAGAAGAAAAGGGTGGGGACGGAATGAATAGTAGATTGAAGACCAAATCAGGGAGCCCGGGCTGA GCTATGGGTGAGGAACTGAAGAACTCAGATCCCTAAGTAGGTGGGGTACCCCTGAGAGGACTGCCACATTTCATTAAGGAAGAGGGGTGC CTAATCTATTCCTGACATGTCTCCTCTCTTCTCCAGGAGCTCACTGACCCAAAGATTTGCACCGTGTGGGTCTGACCTCATCATGTGGAG TGCAGAGGGCCCTGATGACATGTGTGTGATGAGGACCATGACCCTTGAACCCCCTTACCTAACGTAACTAATAAAATGAAGCTGAGAGCT >In-frame_SHMT2_ENST00000557487_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_2295nt CTTCTTCCGACAGCTTGCTGCCCTAGACCAGAGTTGGTGGCTGGACCTCCTGCGACTTCCGAGTTGCGATGCTGTACTTCTCTTTGTTTT GGGCGGCTCGGCCTCTGCAGAGATGTGGGCAGCTGGTCAGGATGGCCATTCGGGCTCAGCACAGCAACGCAGCCCAGACTCAGACTGGGG AAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGACAGTGATCCTGAGATGTGGGAGTTGCTGCAGAGGGAGAAGGACAGGCAGT GTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGCCGAGCTGCGCTGGAGGCCCTGGGGTCCTGTCTGAACAACAAGTACTCGG AGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTG ACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTC ACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCATCTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCA TCTTCTTCGAGTCTATGCCCTATAAGCTCAACCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCT ATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCC TGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAG GGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTG CCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCC GGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTG ACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCA ACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTG AGGATGACTTCCGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCTCCTCCAGGTCCCG GGGCTCTGCATCCTGAGCTATCCAACACCACTGTACTTTGGGACCCGTGGGCAGTTTCGCTGCAACCTGGAGTGGCACCTGGGGCTCGGA GAAGGAGAAAAGGAGACTTCAAAGCCAGATGGCCCAATGGTTGCAGTTGCTGAGCCTGTCAGGGTGGTGGTCCTAGACTTCAGTGGTGTC ACCTTTGCAGATGCTGCTGGGGCCAGAGAAGTGGTGCAGGTGAGGGAGAGGCTGGCCAGCCGATGTCGAGATGCTAGGATCCGCCTCCTC CTGGCTCAGTGTAATGCCTTGGTGCAGGGGACACTGACCCGGGTAGGACTCCTGGACAGGGTGACTCCAGATCAGCTGTTTGTGAGTGTG CAGGATGCAGCTGCTTATGCCCTGGGGAGCCTGTTAAGGGGCAGTAGCACCAGGAGCGGGAGCCAGGAGGCACTGGGCTGCGGCAAGTGA GGCAGGGGTAAGTGGCTGGAGACCCAGGGAGAGGGGTTTGGGAAAGGGTCTGAGGAAGATCAAGAAGAAAAGGGTGGGGACGGAATGAAT AGTAGATTGAAGACCAAATCAGGGAGCCCGGGCTGAGCTATGGGTGAGGAACTGAAGAACTCAGATCCCTAAGTAGGTGGGGTACCCCTG AGAGGACTGCCACATTTCATTAAGGAAGAGGGGTGCCTAATCTATTCCTGACATGTCTCCTCTCTTCTCCAGGAGCTCACTGACCCAAAG ATTTGCACCGTGTGGGTCTGACCTCATCATGTGGAGTGCAGAGGGCCCTGATGACATGTGTGTGATGAGGACCATGACCCTTGAACCCCC >In-frame_SHMT2_ENST00000414700_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_2383nt GCGGACCCGGTGCTGGCAAATGAGCGGAGTTTTCGGCCTGGTCTCACAAGCTGAGCCTTTCCGGCCAGCTCTGAGCCCTGCAGATGATGC AACCGAGCTTCACTGCTTGCATCAGGCAGGGGTCCCGGCGGCAGTGAGGGCTGGAAGGAGGTGGAACGGCCTCTGCAGAGATGTGGGCAG CTGGTCAGGATGGCCATTCGGGCTCAGCACAGCAACGCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGC CTGTCGGACAGTGATCCTGAGATGTGGGAGTTGCTGCAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAAC TTCTGCAGCCGAGCTGCGCTGGAGGCCCTGGGGTCCTGTCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGA GCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTC CAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGAT GGGGGCCATCTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAAC CCCAAAACTGGCCTCATTGACTACAACCAGCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCTAT GCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCCTG GTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGG CTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTGCC GTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGG GAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTGAC AACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAAC AAGAACACCTGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAG GATGACTTCCGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCTCCTCCAGGTCCCGGG GCTCTGCATCCTGAGCTATCCAACACCACTGTACTTTGGGACCCGTGGGCAGTTTCGCTGCAACCTGGAGTGGCACCTGGGGCTCGGAGA AGGAGAAAAGGAGACTTCAAAGCCAGATGGCCCAATGGTTGCAGTTGCTGAGCCTGTCAGGGTGGTGGTCCTAGACTTCAGTGGTGTCAC CTTTGCAGATGCTGCTGGGGCCAGAGAAGTGGTGCAGGTGAGGGAGAGGCTGGCCAGCCGATGTCGAGATGCTAGGATCCGCCTCCTCCT GGCTCAGTGTAATGCCTTGGTGCAGGGGACACTGACCCGGGTAGGACTCCTGGACAGGGTGACTCCAGATCAGCTGTTTGTGAGTGTGCA GGATGCAGCTGCTTATGCCCTGGGGAGCCTGTTAAGGGGCAGTAGCACCAGGAGCGGGAGCCAGGAGGCACTGGGCTGCGGCAAGTGAGG CAGGGGTAAGTGGCTGGAGACCCAGGGAGAGGGGTTTGGGAAAGGGTCTGAGGAAGATCAAGAAGAAAAGGGTGGGGACGGAATGAATAG TAGATTGAAGACCAAATCAGGGAGCCCGGGCTGAGCTATGGGTGAGGAACTGAAGAACTCAGATCCCTAAGTAGGTGGGGTACCCCTGAG AGGACTGCCACATTTCATTAAGGAAGAGGGGTGCCTAATCTATTCCTGACATGTCTCCTCTCTTCTCCAGGAGCTCACTGACCCAAAGAT TTGCACCGTGTGGGTCTGACCTCATCATGTGGAGTGCAGAGGGCCCTGATGACATGTGTGTGATGAGGACCATGACCCTTGAACCCCCTT >In-frame_SHMT2_ENST00000553474_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_2317nt ACGGACTGCTAAAGGTCTCCCCTCCCACCTGCATTGCTCTACAATCTGTGGCCTCAGCCCTTGCCAACTCTGCCTCTTCCCCCGCTGACT GGGCCTCTGCAGAGATGTGGGCAGCTGGTCAGGATGGCCATTCGGGCTCAGCACAGCAACGCAGCCCAGACTCAGACTGGGGAAGCAAAC AGGGGCTGGACAGGCCAGGAGAGCCTGTCGGACAGTGATCCTGAGATGTGGGAGTTGCTGCAGAGGGAGAAGGACAGGCAGTGTCGTGGC CTGGAGCTCATTGCCTCAGAGAACTTCTGCAGCCGAGCTGCGCTGGAGGCCCTGGGGTCCTGTCTGAACAACAAGTACTCGGAGGGTTAT CCTGGCAAGAGATACTATGGGGGAGCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTGACCTGGAT CCTGCACAGTGGGGAGTCAATGTCCAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTCACGACCGG ATCATGGGGCTGGACCTGCCCGATGGGGGCCATCTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCATCTTCTTC GAGTCTATGCCCTATAAGCTCAACCCCAAAACTGGCCTCATTGACTACAACCAGCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTC ATCATAGCTGGCACCAGCGCCTATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCA GACATGGCCCACATCAGTGGCCTGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAG ACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACA TTTGAGGACCGAATCAACTTTGCCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAG CAGGCCTGCACCCCCATGTTCCGGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTAC TCACTGGTATCAGGTGGTACTGACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTA GAGCTTGTATCCATCACTGCCAACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCC TTAACTTCTCGACAGTTCCGTGAGGATGACTTCCGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGC AAGACTGCTCCTCCAGGTCCCGGGGCTCTGCATCCTGAGCTATCCAACACCACTGTACTTTGGGACCCGTGGGCAGTTTCGCTGCAACCT GGAGTGGCACCTGGGGCTCGGAGAAGGAGAAAAGGAGACTTCAAAGCCAGATGGCCCAATGGTTGCAGTTGCTGAGCCTGTCAGGGTGGT GGTCCTAGACTTCAGTGGTGTCACCTTTGCAGATGCTGCTGGGGCCAGAGAAGTGGTGCAGGTGAGGGAGAGGCTGGCCAGCCGATGTCG AGATGCTAGGATCCGCCTCCTCCTGGCTCAGTGTAATGCCTTGGTGCAGGGGACACTGACCCGGGTAGGACTCCTGGACAGGGTGACTCC AGATCAGCTGTTTGTGAGTGTGCAGGATGCAGCTGCTTATGCCCTGGGGAGCCTGTTAAGGGGCAGTAGCACCAGGAGCGGGAGCCAGGA GGCACTGGGCTGCGGCAAGTGAGGCAGGGGTAAGTGGCTGGAGACCCAGGGAGAGGGGTTTGGGAAAGGGTCTGAGGAAGATCAAGAAGA AAAGGGTGGGGACGGAATGAATAGTAGATTGAAGACCAAATCAGGGAGCCCGGGCTGAGCTATGGGTGAGGAACTGAAGAACTCAGATCC CTAAGTAGGTGGGGTACCCCTGAGAGGACTGCCACATTTCATTAAGGAAGAGGGGTGCCTAATCTATTCCTGACATGTCTCCTCTCTTCT CCAGGAGCTCACTGACCCAAAGATTTGCACCGTGTGGGTCTGACCTCATCATGTGGAGTGCAGAGGGCCCTGATGACATGTGTGTGATGA >In-frame_SHMT2_ENST00000449049_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_2525nt ATTGCTCTACAATCTGTGGCCTCAGCCCTTGCCAACTCTGCCTCTTCCCCCGCTGACTGGGGTATCAGTTTATGGTGCCCTGCAGGAAGA CCCTCTTGTTCCTGTGGGTGGGAAGGTTCTGGAATCTCAGTTGCCCTCTCTGGAGTTGGGGAGACATAGGCTTTTGGAGGACAAGCTTTG CAGAGTGGTTCATGGAGTGAGGTGGTGGGAGATTTCTGAGGTGCGGTGCGGTGAATGGAGCAAATCAGAACCACCCCTTGGACGTTGATC TCAAGCTTGGCTCCAGAACTGGCTTTTGAAGCCTCTGCAGAGATGTGGGCAGCTGGTCAGGATGGCCATTCGGGCTCAGCACAGCAACGC AGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGACAGTGATCCTGAGATGTGGGAGTTGCTGCA GAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGAACTTCTGCAGCCGAGCTGCGCTGGAGGCCCTGGGGTCCTG TCTGAACAACAAGTACTCGGAGGGTTATCCTGGCAAGAGATACTATGGGGGAGCAGAGGTGGTGGATGAAATTGAGCTGCTGTGCCAGCG CCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCCTACTCCGGGTCCCCAGCCAACCTGGCCGTCTA CACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGCCATCTCACCCACGGCTACATGTCTGACGTCAA GCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACCCCAAAACTGGCCTCATTGACTACAACCAGCTGGCACT GACTGCTCGACTTTTCCGGCCACGGCTCATCATAGCTGGCACCAGCGCCTATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTGTG TGATGAAGTCAAAGCACACCTGCTGGCAGACATGGCCCACATCAGTGGCCTGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCACGC GGACATCGTCACCACCACTACTCACAAGACTCTTCGAGGGGCCAGGTCAGGGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGACCC CAAGACTGGCCGGGAGATCCCTTACACATTTGAGGACCGAATCAACTTTGCCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCATGC CATTGCTGCAGTAGCTGTGGCCCTAAAGCAGGCCTGCACCCCCATGTTCCGGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCCAT GGCAGATGCCCTGCTAGAGCGAGGCTACTCACTGGTATCAGGTGGTACTGACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGCCT GGATGGAGCTCGGGCTGAGCGGGTGCTAGAGCTTGTATCCATCACTGCCAACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCACACC GGGCGGCCTGCGGCTTGGGGCCCCAGCCTTAACTTCTCGACAGTTCCGTGAGGATGACTTCCGGAGAGTTGTGGACTTTATAGATGAAGG GGTCAACATTGGCTTAGAGGTGAAGAGCAAGACTGCTCCTCCAGGTCCCGGGGCTCTGCATCCTGAGCTATCCAACACCACTGTACTTTG GGACCCGTGGGCAGTTTCGCTGCAACCTGGAGTGGCACCTGGGGCTCGGAGAAGGAGAAAAGGAGACTTCAAAGCCAGATGGCCCAATGG TTGCAGTTGCTGAGCCTGTCAGGGTGGTGGTCCTAGACTTCAGTGGTGTCACCTTTGCAGATGCTGCTGGGGCCAGAGAAGTGGTGCAGG TGAGGGAGAGGCTGGCCAGCCGATGTCGAGATGCTAGGATCCGCCTCCTCCTGGCTCAGTGTAATGCCTTGGTGCAGGGGACACTGACCC GGGTAGGACTCCTGGACAGGGTGACTCCAGATCAGCTGTTTGTGAGTGTGCAGGATGCAGCTGCTTATGCCCTGGGGAGCCTGTTAAGGG GCAGTAGCACCAGGAGCGGGAGCCAGGAGGCACTGGGCTGCGGCAAGTGAGGCAGGGGTAAGTGGCTGGAGACCCAGGGAGAGGGGTTTG GGAAAGGGTCTGAGGAAGATCAAGAAGAAAAGGGTGGGGACGGAATGAATAGTAGATTGAAGACCAAATCAGGGAGCCCGGGCTGAGCTA TGGGTGAGGAACTGAAGAACTCAGATCCCTAAGTAGGTGGGGTACCCCTGAGAGGACTGCCACATTTCATTAAGGAAGAGGGGTGCCTAA TCTATTCCTGACATGTCTCCTCTCTTCTCCAGGAGCTCACTGACCCAAAGATTTGCACCGTGTGGGTCTGACCTCATCATGTGGAGTGCA GAGGGCCCTGATGACATGTGTGTGATGAGGACCATGACCCTTGAACCCCCTTACCTAACGTAACTAATAAAATGAAGCTGAGAGCTTTGG >In-frame_SHMT2_ENST00000393827_chr12_57627893_+_SLC26A10_ENST00000379218_chr12_58018649_+_2225nt ACAATCTGTGGCCTCAGCCCTTGCCAACTCTGCCTCTTCCCCCGCTGACTGGGCCTCTGCAGAGATGTGGGCAGCTGGTCAGGATGGCCA TTCGGGCTCAGCACAGCAACGCAGCCCAGACTCAGACTGGGGAAGCAAACAGGGGCTGGACAGGCCAGGAGAGCCTGTCGGACAGTGATC CTGAGATGTGGGAGTTGCTGCAGAGGGAGAAGGACAGGCAGTGTCGTGGCCTGGAGCTCATTGCCTCAGAGATACTATGGGGGAGCAGAG GTGGTGGATGAAATTGAGCTGCTGTGCCAGCGCCGGGCCTTGGAAGCCTTTGACCTGGATCCTGCACAGTGGGGAGTCAATGTCCAGCCC TACTCCGGGTCCCCAGCCAACCTGGCCGTCTACACAGCCCTTCTGCAACCTCACGACCGGATCATGGGGCTGGACCTGCCCGATGGGGGC CATCTCACCCACGGCTACATGTCTGACGTCAAGCGGATATCAGCCACGTCCATCTTCTTCGAGTCTATGCCCTATAAGCTCAACGGCTTT AGCTGTTTGTGTGTCTGTCCAGCCCAAAACTGGCCTCATTGACTACAACCAGCTGGCACTGACTGCTCGACTTTTCCGGCCACGGCTCAT CATAGCTGGCACCAGCGCCTATGCTCGCCTCATTGACTACGCCCGCATGAGAGAGGTGTGTGATGAAGTCAAAGCACACCTGCTGGCAGA CATGGCCCACATCAGTGGCCTGGTGGCTGCCAAGGTGATTCCCTCGCCTTTCAAGCACGCGGACATCGTCACCACCACTACTCACAAGAC TCTTCGAGGGGCCAGGTCAGGGCTCATCTTCTACCGGAAAGGGGTGAAGGCTGTGGACCCCAAGACTGGCCGGGAGATCCCTTACACATT TGAGGACCGAATCAACTTTGCCGTGTTCCCATCCCTGCAGGGGGGCCCCCACAATCATGCCATTGCTGCAGTAGCTGTGGCCCTAAAGCA GGCCTGCACCCCCATGTTCCGGGAGTACTCCCTGCAGGTTCTGAAGAATGCTCGGGCCATGGCAGATGCCCTGCTAGAGCGAGGCTACTC ACTGGTATCAGGTGGTACTGACAACCACCTGGTGCTGGTGGACCTGCGGCCCAAGGGCCTGGATGGAGCTCGGGCTGAGCGGGTGCTAGA GCTTGTATCCATCACTGCCAACAAGAACACCTGTCCTGGAGACCGAAGTGCCATCACACCGGGCGGCCTGCGGCTTGGGGCCCCAGCCTT AACTTCTCGACAGTTCCGTGAGGATGACTTCCGGAGAGTTGTGGACTTTATAGATGAAGGGGTCAACATTGGCTTAGAGGTGAAGAGCAA GACTGCTCCTCCAGGTCCCGGGGCTCTGCATCCTGAGCTATCCAACACCACTGTACTTTGGGACCCGTGGGCAGTTTCGCTGCAACCTGG AGTGGCACCTGGGGCTCGGAGAAGGAGAAAAGGAGACTTCAAAGCCAGATGGCCCAATGGTTGCAGTTGCTGAGCCTGTCAGGGTGGTGG TCCTAGACTTCAGTGGTGTCACCTTTGCAGATGCTGCTGGGGCCAGAGAAGTGGTGCAGGTGAGGGAGAGGCTGGCCAGCCGATGTCGAG ATGCTAGGATCCGCCTCCTCCTGGCTCAGTGTAATGCCTTGGTGCAGGGGACACTGACCCGGGTAGGACTCCTGGACAGGGTGACTCCAG ATCAGCTGTTTGTGAGTGTGCAGGATGCAGCTGCTTATGCCCTGGGGAGCCTGTTAAGGGGCAGTAGCACCAGGAGCGGGAGCCAGGAGG CACTGGGCTGCGGCAAGTGAGGCAGGGGTAAGTGGCTGGAGACCCAGGGAGAGGGGTTTGGGAAAGGGTCTGAGGAAGATCAAGAAGAAA AGGGTGGGGACGGAATGAATAGTAGATTGAAGACCAAATCAGGGAGCCCGGGCTGAGCTATGGGTGAGGAACTGAAGAACTCAGATCCCT AAGTAGGTGGGGTACCCCTGAGAGGACTGCCACATTTCATTAAGGAAGAGGGGTGCCTAATCTATTCCTGACATGTCTCCTCTCTTCTCC AGGAGCTCACTGACCCAAAGATTTGCACCGTGTGGGTCTGACCTCATCATGTGGAGTGCAGAGGGCCCTGATGACATGTGTGTGATGAGG |
Top |
FusionGenePPI for SHMT2_SLC26A10 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SHMT2 | EIF1B, GNAS, BRCC3, BRE, BABAM1, DDA1, UBA5, ICT1, PPARD, HDAC5, NDRG1, CUL3, CUL1, APP, ATF2, ADRB2, APEH, CAND1, CTTN, GSPT2, IDE, NASP, ARFIP1, ATG7, ATP6V1C1, CUL5, CYHR1, H1FX, HIST1H1B, IVNS1ABP, JMJD6, LUC7L2, PAWR, PSMG3, SEC24D, SHMT1, SNX1, STAT1, TBC1D15, VPS35, SNX6, HUWE1, ARL6IP1, CMTM5, NOC2L, HES4, MTOR, UBR4, HP1BP3, E2F2, RSRP1, ARID1A, MAP3K6, RCC1, ZBTB8OS, YARS, KIAA0754, BMP8B, SZT2, LRRC42, MRPL37, DNAJB4, CCBL2, SNORD21, SNORA66, FNBP1L, PALMD, STRIP1, NOTCH2NL, MRPS21, GOLPH3L, PRUNE, S100A11, TPM3, KIAA0907, LMNA, MEF2D, COPA, NDUFS2, SNORD76, RABGAP1L, SCARNA3, C1orf21, LIN9, PARP1, AHCTF1, FAM110C, PTRHD1, GPATCH11, LRPPRC, CAMKMT, EFEMP1, MEIS1, POLR1A, COX5B, PDCL3, NPAS2, BIN1, IWS1, NAB1, FAM117B, ABI2, COL4A3, SCARNA5, HJURP, ATG4B, ZNF860, SNORA6, RBM6, ARHGEF3, THOC7, CCDC58, ISY1, MBD4, RYK, MRPS22, ACTL6A, ABCC5, SNORA63, XXYLT1, DGKQ, EVC, GRPEL1, HSP90AB2P, MED28, OCIAD1, SEC31A, MRPS18C, WDFY3, HERC3, FAT4, HMGB2, NR2F1-AS1, SNORA13, TNFAIP8, RAPGEF6, HSPA4, HSPA9, SNORA74A, HARS2, FBXO38, STK10, SNORA74B, UIMC1, GRK6, PDLIM7, DDX41, HNRNPAB, EXOC2, BPHL, FARS2, SCARNA27, TBC1D7, RNF144B, HIST1H4E, HIST1H2AE, HIST1H4I, HIST1H2BO, PBX2, ZNF76, NFYA, MRPS10, TRERF1, TTK, SNX14, ZUFSP, SNORA33, IFNGR1, HEBP2, FBXO5, SCAF8, TFB1M, WDR27, SNX8, NOD1, SNORA5A, CRCP, GATAD1, SAMD9, PTCD1, ATP5J2-PTCD1, TRIP6, PMPCB, PSMC2, LOC407835, COPG2, NUP205, LOC155060, ABCF2, DMTN, BIN3, GTF2E2, SNORD54, MTFR1, STAU2, GDAP1, RIPK2, DECR1, PLEKHF2, YWHAZ, UTP23, ZNF623, SCRIB, KANK1, KIAA0020, KDM4C, MPDZ, ACO1, NFX1, UBAP1, TLN1, CREB3, HINT2, C9orf40, NOL8, NANS, CCP110, TTLL11, HSPA5, CCBL1, FNBP1, SNORD24, SNORA43, SNORA17, DPH7, USP6NL, KIAA1217, CUL2, BMS1, HERC4, DNA2, AGAP11, ALDH18A1, GOT1, C10orf76, BBIP1, SNORA52, SNORA54, DNHD1, ILK, ZNF215, SNORA45B, COPB1, ELP4, MADD, PSMC3, NDUFS3, CPSF7, FEN1, SNORD22, SSH3, RELT, SNORA8, ANKRD49, AMOTL1, ENDOD1, IL18, CEP164, VPS11, HINFP, FOXRED1, CPNE8, KIF21A, PPHLN1, HDAC7, LIMA1, RAB5B, SMARCC2, CS, SPRYD4, INHBE, RASSF9, NTN4, APAF1, MIR3652, PXN, RNF10, USPL1, INTS6, PIBF1, RAP2A, FKSG29, TUBGCP3, PCID2, SNORD9, MLH3, FLVCR2, GTF2A1, DDX24, BTBD6, WHAMMP2, AQR, KNSTRN, CHP1, ADAL, TP53BP1, PIN4P1, GABPB1-AS1, TMOD2, TCF12, GCOM1, MYO1E, HMG20A, RHBDF1, CLUAP1, SPN, SNORA30, C16orf93, RPGRIP1L, ARL2BP, NUTF2, EDC4, NFATC3, PDPR, DHX38, OSGIN1, KLHDC4, PRPF8, WDR81, CHD3, PFAS, POLDIP2, ALDOC, MYO18A, COPRS, ZNF207, SNORD7, SNORA21, RAPGEFL1, NT5C3B, STAT3, AOC2, DHX8, HEXIM1, LUC7L3, SRSF1, MKS1, METTL2A, STRADA, SNORD104, PLEKHM1P, SAP30BP, EXOC7, SCARNA16, TBC1D16, HGS, NDC80, FAM210A, TTC39C, ELP2, MBD1, PIGN, ADNP2, WDR18, GIPC3, HNRNPM, TYK2, SNORD41, RNASEH2A, AKAP8L, RAB8A, UNC13A, CRLF1, COPE, RFXANK, ZNF792, SUPT5H, ATP1A3, CADM4, PPP5C, STRN4, PRMT1, ZNF419, ZNF544, ZNF8, A1BG, NOP56, ITPA, XRN2, RALY, CEP250, ZNFX1, GMEB2, BACH1, CRYZL1, NDUFV3, NIPSNAP1, TAB1, ATF4, XRCC6, CA5B, POLA1, RBM10, EBP, HDAC6, SPIN4, PIN4, MORC4, GLUD2, ENOX2, MBNL3, DKC1, FUNDC2, CUL7, OBSL1, ESR1, ILF2, FBXW11, DCTN2, DDX1, EIF4EBP1, HSPE1, MAPK12, NAPRT, SCLY, ATP6V1A, EZR, GORASP2, NLRP13, PAFAH1B2, PPP1R8, PRRC1, RHOA, YWHAE, NTRK1, CTR9, U2AF2, PPM1G, FAM175B, TMEM184A, DYNLL2, DYNLL1, DLD, PDHA1, SDHA, SOAT1 | SLC26A10 | TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SHMT2_SLC26A10 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | SHMT2 | P34897 | DB11638 | Artenimol | Serine hydroxymethyltransferase, mitochondrial | small molecule | approved|investigational |
| Hgene | SHMT2 | P34897 | DB00114 | Pyridoxal Phosphate | Serine hydroxymethyltransferase, mitochondrial | small molecule | approved|investigational|nutraceutical |
| Hgene | SHMT2 | P34897 | DB00145 | Glycine | Serine hydroxymethyltransferase, mitochondrial | small molecule | approved|nutraceutical|vet_approved |
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RelatedDiseases for SHMT2_SLC26A10 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SHMT2 | C0007131 | Non-Small Cell Lung Carcinoma | 1 | CTD_human |
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