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Fusion gene ID: 33692 |
FusionGeneSummary for SH3RF1_SPOCK3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SH3RF1_SPOCK3 | Fusion gene ID: 33692 | Hgene | Tgene | Gene symbol | SH3RF1 | SPOCK3 | Gene ID | 57630 | 50859 |
| Gene name | SH3 domain containing ring finger 1 | SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 | |
| Synonyms | POSH|RNF142|SH3MD2 | HSAJ1454|TES-3|TICN3 | |
| Cytomap | 4q32.3-q33 | 4q32.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase SH3RF1RING-type E3 ubiquitin transferase SH3RF1SH3 domain-containing RING finger protein 1SH3 multiple domains 2SH3 multiple domains protein 2plenty of SH3 domainsplenty of SH3sputative E3 ubiquitin-protein ligase SH3RF1 | testican-3SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q7Z6J0 | Q9BQ16 | |
| Ensembl transtripts involved in fusion gene | ENST00000284637, ENST00000508685, | ENST00000357154, ENST00000357545, ENST00000504953, ENST00000511531, ENST00000506886, ENST00000507137, ENST00000510741, ENST00000502330, ENST00000541354, ENST00000512681, ENST00000511269, ENST00000535728, ENST00000421836, ENST00000534949, ENST00000541637, ENST00000512648, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 3 X 3 X 2=18 |
| # samples | 6 | 3 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SH3RF1 [Title/Abstract] AND SPOCK3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-AZ-6607-01A | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000284637 | ENST00000357154 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| In-frame | ENST00000284637 | ENST00000357545 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| In-frame | ENST00000284637 | ENST00000504953 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| In-frame | ENST00000284637 | ENST00000511531 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| In-frame | ENST00000284637 | ENST00000506886 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000507137 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000510741 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000502330 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000541354 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000512681 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000511269 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000535728 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000421836 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000534949 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000541637 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5CDS-5UTR | ENST00000284637 | ENST00000512648 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-3CDS | ENST00000508685 | ENST00000357154 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-3CDS | ENST00000508685 | ENST00000357545 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-3CDS | ENST00000508685 | ENST00000504953 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-3CDS | ENST00000508685 | ENST00000511531 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-3CDS | ENST00000508685 | ENST00000506886 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000507137 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000510741 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000502330 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000541354 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000512681 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000511269 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000535728 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000421836 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000534949 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000541637 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
| 5UTR-5UTR | ENST00000508685 | ENST00000512648 | SH3RF1 | chr4 | 170057469 | - | SPOCK3 | chr4 | 167810395 | - |
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FusionProtFeatures for SH3RF1_SPOCK3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SH3RF1 | SPOCK3 |
| Has E3 ubiquitin-protein ligase activity. In the absenceof an external substrate, it can catalyze self-ubiquitination(PubMed:15659549, PubMed:20696164). Stimulates ubiquitination ofpotassium channel KCNJ1, enhancing it's dynamin-dependent andclathrin-independent endocytosis (PubMed:19710010). Acts as ascaffold protein that coordinates with MAPK8IP1/JIP1 in organizingdifferent components of the JNK pathway, including RAC1 or RAC2,MAP3K11/MLK3 or MAP3K7/TAK1, MAP2K7/MKK7, MAPK8/JNK1 and/orMAPK9/JNK2 into a functional multiprotein complex to ensure theeffective activation of the JNK signaling pathway. Regulates thedifferentiation of CD4(+) and CD8(+) T-cells and promotes T-helper1 (Th1) cell differentiation. Regulates the activation ofMAPK8/JNK1 and MAPK9/JNK2 in CD4(+) T-cells and the activation ofMAPK8/JNK1 in CD8(+) T-cells. Plays a crucial role in themigration of neocortical neurons in the developing brain. Controlsproper cortical neuronal migration and the formation of proximalcytoplasmic dilation in the leading process (PCDLP) in migratoryneocortical neurons by regulating the proper localization ofactivated RAC1 and F-actin assembly (By similarity).{ECO:0000250|UniProtKB:Q69ZI1, ECO:0000269|PubMed:15659549,ECO:0000269|PubMed:19710010, ECO:0000269|PubMed:20696164}. (Microbial infection) Plays an essential role in thetargeting of HIV-1 Gag to the plasma membrane, this function isdependent on it's RING domain, and hence it's E3 ligase activity.{ECO:0000269|PubMed:15659549}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 134_193 | 356 | 889 | Domain | SH3 1 |
| Hgene | SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 196_259 | 356 | 889 | Domain | SH3 2 |
| Hgene | SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 12_53 | 356 | 889 | Zinc finger | RING-type |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000357154 | - | 5 | 12 | 394_436 | 161 | 437 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000357545 | - | 4 | 11 | 394_436 | 158 | 434 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000421836 | - | 5 | 12 | 394_436 | 110 | 386 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000502330 | - | 5 | 12 | 394_436 | 161 | 437 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000504953 | - | 4 | 11 | 394_436 | 158 | 434 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000506886 | - | 5 | 12 | 394_436 | 161 | 437 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000510741 | - | 4 | 10 | 394_436 | 158 | 394 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000511269 | - | 3 | 10 | 394_436 | 158 | 434 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000511531 | - | 5 | 12 | 394_436 | 161 | 437 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000512648 | - | 4 | 8 | 394_436 | 158 | 314 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000512681 | - | 1 | 8 | 394_436 | 63 | 339 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000534949 | - | 1 | 8 | 394_436 | 65 | 341 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000541354 | - | 3 | 10 | 394_436 | 41 | 317 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000541637 | - | 0 | 7 | 394_436 | 63 | 339 | Compositional bias | Note=Asp-rich |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000357154 | - | 5 | 12 | 314_380 | 161 | 437 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000357545 | - | 4 | 11 | 314_380 | 158 | 434 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000421836 | - | 5 | 12 | 133_185 | 110 | 386 | Domain | Kazal-like |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000421836 | - | 5 | 12 | 314_380 | 110 | 386 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000502330 | - | 5 | 12 | 314_380 | 161 | 437 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000504953 | - | 4 | 11 | 314_380 | 158 | 434 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000506886 | - | 5 | 12 | 314_380 | 161 | 437 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000510741 | - | 4 | 10 | 314_380 | 158 | 394 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000511269 | - | 3 | 10 | 314_380 | 158 | 434 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000511531 | - | 5 | 12 | 314_380 | 161 | 437 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000512648 | - | 4 | 8 | 314_380 | 158 | 314 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000512681 | - | 1 | 8 | 133_185 | 63 | 339 | Domain | Kazal-like |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000512681 | - | 1 | 8 | 314_380 | 63 | 339 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000534949 | - | 1 | 8 | 133_185 | 65 | 341 | Domain | Kazal-like |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000534949 | - | 1 | 8 | 314_380 | 65 | 341 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000541354 | - | 3 | 10 | 133_185 | 41 | 317 | Domain | Kazal-like |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000541354 | - | 3 | 10 | 314_380 | 41 | 317 | Domain | Thyroglobulin type-1 |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000541637 | - | 0 | 7 | 133_185 | 63 | 339 | Domain | Kazal-like |
| Tgene | >SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000541637 | - | 0 | 7 | 314_380 | 63 | 339 | Domain | Thyroglobulin type-1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 397_403 | 356 | 889 | Compositional bias | Note=Poly-Pro |
| Hgene | >SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 417_424 | 356 | 889 | Compositional bias | Note=Poly-Ala |
| Hgene | >SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 657_662 | 356 | 889 | Compositional bias | Note=Poly-Ala |
| Hgene | >SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 445_506 | 356 | 889 | Domain | SH3 3 |
| Hgene | >SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 829_888 | 356 | 889 | Domain | SH3 4 |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000357154 | - | 5 | 12 | 133_185 | 161 | 437 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000357545 | - | 4 | 11 | 133_185 | 158 | 434 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000502330 | - | 5 | 12 | 133_185 | 161 | 437 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000504953 | - | 4 | 11 | 133_185 | 158 | 434 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000506886 | - | 5 | 12 | 133_185 | 161 | 437 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000510741 | - | 4 | 10 | 133_185 | 158 | 394 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000511269 | - | 3 | 10 | 133_185 | 158 | 434 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000511531 | - | 5 | 12 | 133_185 | 161 | 437 | Domain | Kazal-like |
| Tgene | SPOCK3 | chr4:170057469 | chr4:167810395 | ENST00000512648 | - | 4 | 8 | 133_185 | 158 | 314 | Domain | Kazal-like |
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FusionGeneSequence for SH3RF1_SPOCK3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000357154_chr4_167810395_-_632aa MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSG TNCTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIH GFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPP VPGVDAGECSSAAAQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQCKLE YQACVLGKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGW MFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDG YYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGGDDHDVY >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000357545_chr4_167810395_-_632aa MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSG TNCTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIH GFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPP VPGVDAGECSSAAAQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQCKLE YQACVLGKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGW MFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDG YYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGGDDHDVY >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000504953_chr4_167810395_-_632aa MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSG TNCTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIH GFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPP VPGVDAGECSSAAAQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQCKLE YQACVLGKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGW MFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDG YYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGGDDHDVY >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000511531_chr4_167810395_-_632aa MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSG TNCTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIH GFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPP VPGVDAGECSSAAAQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQCKLE YQACVLGKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGW MFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDG YYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGGDDHDVY >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000506886_chr4_167810395_-_632aa MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSG TNCTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIH GFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPP VPGVDAGECSSAAAQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQCKLE YQACVLGKQISVKCEGHCPCPSDKPTSTSRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKTLLRPERSRFDTSILPICKDSLGW MFNRLDTNYDLLLDQSELRSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDG YYKPTQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIMNDEDEIEDDDEDEGDDDDGGDDHDVY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000357154_chr4_167810395_-_1896nt ATGGATGAATCAGCCTTGTTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCAT ACGTTTTGCAAGCGATGTTTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTC GAGGAGCTTCCCAGTAACATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGG ACCAACTGCACAAATGCATTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAG CCTCGGGTGCAATCCTGGAGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCT GGAGACCTTAAATTCAGCAAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCAT GGCTTTTTCCCCACCAACTTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAA GACAAGGAAGCAGACAAAGATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGA ATGCTGGCAGACAAAATAGGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCT GTGCCAGGAGTTGATGCTGGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAA AAGCGGCACTCCTTCACTTCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTC CTCATCAGCTCCAGCAACCCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAA TATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGA AATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGT CAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGG ATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACC AAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCA CCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGT TACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAAT GGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAA GACGATATTATGAATGATGAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATAC >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000357545_chr4_167810395_-_1896nt ATGGATGAATCAGCCTTGTTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCAT ACGTTTTGCAAGCGATGTTTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTC GAGGAGCTTCCCAGTAACATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGG ACCAACTGCACAAATGCATTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAG CCTCGGGTGCAATCCTGGAGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCT GGAGACCTTAAATTCAGCAAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCAT GGCTTTTTCCCCACCAACTTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAA GACAAGGAAGCAGACAAAGATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGA ATGCTGGCAGACAAAATAGGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCT GTGCCAGGAGTTGATGCTGGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAA AAGCGGCACTCCTTCACTTCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTC CTCATCAGCTCCAGCAACCCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAA TATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGA AATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGT CAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGG ATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACC AAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCA CCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGT TACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAAT GGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAA GACGATATTATGAATGATGAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATAC >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000504953_chr4_167810395_-_1896nt ATGGATGAATCAGCCTTGTTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCAT ACGTTTTGCAAGCGATGTTTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTC GAGGAGCTTCCCAGTAACATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGG ACCAACTGCACAAATGCATTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAG CCTCGGGTGCAATCCTGGAGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCT GGAGACCTTAAATTCAGCAAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCAT GGCTTTTTCCCCACCAACTTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAA GACAAGGAAGCAGACAAAGATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGA ATGCTGGCAGACAAAATAGGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCT GTGCCAGGAGTTGATGCTGGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAA AAGCGGCACTCCTTCACTTCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTC CTCATCAGCTCCAGCAACCCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAA TATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGA AATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGT CAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGG ATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACC AAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCA CCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGT TACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAAT GGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAA GACGATATTATGAATGATGAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATAC >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000511531_chr4_167810395_-_1896nt ATGGATGAATCAGCCTTGTTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCAT ACGTTTTGCAAGCGATGTTTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTC GAGGAGCTTCCCAGTAACATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGG ACCAACTGCACAAATGCATTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAG CCTCGGGTGCAATCCTGGAGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCT GGAGACCTTAAATTCAGCAAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCAT GGCTTTTTCCCCACCAACTTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAA GACAAGGAAGCAGACAAAGATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGA ATGCTGGCAGACAAAATAGGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCT GTGCCAGGAGTTGATGCTGGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAA AAGCGGCACTCCTTCACTTCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTC CTCATCAGCTCCAGCAACCCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAA TATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGA AATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGT CAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGG ATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACC AAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCA CCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGT TACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAAT GGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAA GACGATATTATGAATGATGAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATAC >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000506886_chr4_167810395_-_1896nt ATGGATGAATCAGCCTTGTTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCAT ACGTTTTGCAAGCGATGTTTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTC GAGGAGCTTCCCAGTAACATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGG ACCAACTGCACAAATGCATTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAG CCTCGGGTGCAATCCTGGAGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCT GGAGACCTTAAATTCAGCAAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCAT GGCTTTTTCCCCACCAACTTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAA GACAAGGAAGCAGACAAAGATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGA ATGCTGGCAGACAAAATAGGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCT GTGCCAGGAGTTGATGCTGGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAA AAGCGGCACTCCTTCACTTCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTC CTCATCAGCTCCAGCAACCCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAA TATCAGGCATGTGTCTTAGGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGA AATGTTAAGAGAGCATGCAGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGT CAAAACAAGAAGACAAAAACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGG ATGTTTAACAGACTTGATACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACC AAGGCATTCTTCAATTCTTGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCA CCTTGCCAGACTGAGCTCAGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGT TACTACAAGCCAACACAATGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAAT GGTGTTGCAGATTGTGCTATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAA GACGATATTATGAATGATGAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000357154_chr4_167810395_-_3775nt CGCCCCGGGCGCCGGCTGCGTCCCGGCCTCCTCCTCCTCTTCCTCCGCCCTCCTTGGCTGGGAAAGTGGGAGGCGGCGGCGGCGGCGTGG TGTGTGTGCGCGCGTGAGGGGGGCAGCAGAGAGGAGTCTCCCGGTGCCGCCGCGGCGTCAGAGACACTGCGAGCGGCGAGCGCGGTGGGG CCGCATCTGCATCAGCCGCCGCAGCCGCTGCGGGGCCGCGAACAAAGAGGAGGAGCCGAGGCGCGAGAGCAAAGTCTGAAATGGATGTTA CATGAGTCATTTTAAGGGATGCACACAACTATGAACATTTCTGAAGATTTTTTCTCAGTAAAGTAGATAAAGATGGATGAATCAGCCTTG TTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCATACGTTTTGCAAGCGATGT TTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTCGAGGAGCTTCCCAGTAAC ATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGGACCAACTGCACAAATGCA TTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAGCCTCGGGTGCAATCCTGG AGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCTGGAGACCTTAAATTCAGC AAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCATGGCTTTTTCCCCACCAAC TTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAAGACAAGGAAGCAGACAAA GATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGAATGCTGGCAGACAAAATA GGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCTGTGCCAGGAGTTGATGCT GGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAAAAGCGGCACTCCTTCACT TCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTCCTCATCAGCTCCAGCAAC CCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAATATCAGGCATGTGTCTTA GGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGC AGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAA ACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGAT ACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCT TGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTC AGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAA TGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCT ATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGAT GAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTT GAAATCAATAAATTCTACATTTCTAATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAAC CTCACATATATTTTGTATAATTATTTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTT ATATTCCTTACACAAAAAGAAAATACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAA CAAACTTTGTAAATCTTCCATAAGCAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATT TAAAATAAATAAATTTTTAATGACCTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTA GACCTAGTTGAGTCAGGATAACAGAGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAAT AGTGGTGTTTTTACCTATGAAATTATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAA AAATTTAGTTGTTCTCCCCAATGTGTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTT TGCCTTTCTAGATTTCTTTATCTTTCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCA TATTTTTACAAAGTTTGTCATTTGCCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATT TAATCTTAGAATTATGTTATTTTTGTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATT TTAGCATGCATACCAATATAGTATATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATG AAGAAAATGGGATACGTTTGTTTCTTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTA AGATTTAACTGTAGCAAAAATTACTTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTT TAACTATATCATACCAATGGTTTTGTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTG GGTAAACTGGTTTCCCAGTATACAATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAA >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000357545_chr4_167810395_-_3772nt CGCCCCGGGCGCCGGCTGCGTCCCGGCCTCCTCCTCCTCTTCCTCCGCCCTCCTTGGCTGGGAAAGTGGGAGGCGGCGGCGGCGGCGTGG TGTGTGTGCGCGCGTGAGGGGGGCAGCAGAGAGGAGTCTCCCGGTGCCGCCGCGGCGTCAGAGACACTGCGAGCGGCGAGCGCGGTGGGG CCGCATCTGCATCAGCCGCCGCAGCCGCTGCGGGGCCGCGAACAAAGAGGAGGAGCCGAGGCGCGAGAGCAAAGTCTGAAATGGATGTTA CATGAGTCATTTTAAGGGATGCACACAACTATGAACATTTCTGAAGATTTTTTCTCAGTAAAGTAGATAAAGATGGATGAATCAGCCTTG TTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCATACGTTTTGCAAGCGATGT TTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTCGAGGAGCTTCCCAGTAAC ATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGGACCAACTGCACAAATGCA TTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAGCCTCGGGTGCAATCCTGG AGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCTGGAGACCTTAAATTCAGC AAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCATGGCTTTTTCCCCACCAAC TTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAAGACAAGGAAGCAGACAAA GATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGAATGCTGGCAGACAAAATA GGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCTGTGCCAGGAGTTGATGCT GGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAAAAGCGGCACTCCTTCACT TCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTCCTCATCAGCTCCAGCAAC CCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAATATCAGGCATGTGTCTTA GGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGC AGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAA ACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGAT ACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCT TGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTC AGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAA TGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCT ATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGAT GAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTT GAAATCAATAAATTCTACATTTCTAATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAAC CTCACATATATTTTGTATAATTATTTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTT ATATTCCTTACACAAAAAGAAAATACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAA CAAACTTTGTAAATCTTCCATAAGCAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATT TAAAATAAATAAATTTTTAATGACCTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTA GACCTAGTTGAGTCAGGATAACAGAGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAAT AGTGGTGTTTTTACCTATGAAATTATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAA AAATTTAGTTGTTCTCCCCAATGTGTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTT TGCCTTTCTAGATTTCTTTATCTTTCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCA TATTTTTACAAAGTTTGTCATTTGCCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATT TAATCTTAGAATTATGTTATTTTTGTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATT TTAGCATGCATACCAATATAGTATATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATG AAGAAAATGGGATACGTTTGTTTCTTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTA AGATTTAACTGTAGCAAAAATTACTTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTT TAACTATATCATACCAATGGTTTTGTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTG GGTAAACTGGTTTCCCAGTATACAATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAA >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000504953_chr4_167810395_-_3772nt CGCCCCGGGCGCCGGCTGCGTCCCGGCCTCCTCCTCCTCTTCCTCCGCCCTCCTTGGCTGGGAAAGTGGGAGGCGGCGGCGGCGGCGTGG TGTGTGTGCGCGCGTGAGGGGGGCAGCAGAGAGGAGTCTCCCGGTGCCGCCGCGGCGTCAGAGACACTGCGAGCGGCGAGCGCGGTGGGG CCGCATCTGCATCAGCCGCCGCAGCCGCTGCGGGGCCGCGAACAAAGAGGAGGAGCCGAGGCGCGAGAGCAAAGTCTGAAATGGATGTTA CATGAGTCATTTTAAGGGATGCACACAACTATGAACATTTCTGAAGATTTTTTCTCAGTAAAGTAGATAAAGATGGATGAATCAGCCTTG TTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCATACGTTTTGCAAGCGATGT TTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTCGAGGAGCTTCCCAGTAAC ATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGGACCAACTGCACAAATGCA TTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAGCCTCGGGTGCAATCCTGG AGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCTGGAGACCTTAAATTCAGC AAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCATGGCTTTTTCCCCACCAAC TTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAAGACAAGGAAGCAGACAAA GATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGAATGCTGGCAGACAAAATA GGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCTGTGCCAGGAGTTGATGCT GGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAAAAGCGGCACTCCTTCACT TCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTCCTCATCAGCTCCAGCAAC CCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAATATCAGGCATGTGTCTTA GGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGC AGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAA ACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGAT ACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCT TGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTC AGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAA TGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCT ATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGAT GAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTT GAAATCAATAAATTCTACATTTCTAATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAAC CTCACATATATTTTGTATAATTATTTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTT ATATTCCTTACACAAAAAGAAAATACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAA CAAACTTTGTAAATCTTCCATAAGCAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATT TAAAATAAATAAATTTTTAATGACCTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTA GACCTAGTTGAGTCAGGATAACAGAGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAAT AGTGGTGTTTTTACCTATGAAATTATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAA AAATTTAGTTGTTCTCCCCAATGTGTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTT TGCCTTTCTAGATTTCTTTATCTTTCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCA TATTTTTACAAAGTTTGTCATTTGCCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATT TAATCTTAGAATTATGTTATTTTTGTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATT TTAGCATGCATACCAATATAGTATATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATG AAGAAAATGGGATACGTTTGTTTCTTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTA AGATTTAACTGTAGCAAAAATTACTTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTT TAACTATATCATACCAATGGTTTTGTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTG GGTAAACTGGTTTCCCAGTATACAATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAA >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000511531_chr4_167810395_-_3771nt CGCCCCGGGCGCCGGCTGCGTCCCGGCCTCCTCCTCCTCTTCCTCCGCCCTCCTTGGCTGGGAAAGTGGGAGGCGGCGGCGGCGGCGTGG TGTGTGTGCGCGCGTGAGGGGGGCAGCAGAGAGGAGTCTCCCGGTGCCGCCGCGGCGTCAGAGACACTGCGAGCGGCGAGCGCGGTGGGG CCGCATCTGCATCAGCCGCCGCAGCCGCTGCGGGGCCGCGAACAAAGAGGAGGAGCCGAGGCGCGAGAGCAAAGTCTGAAATGGATGTTA CATGAGTCATTTTAAGGGATGCACACAACTATGAACATTTCTGAAGATTTTTTCTCAGTAAAGTAGATAAAGATGGATGAATCAGCCTTG TTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCATACGTTTTGCAAGCGATGT TTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTCGAGGAGCTTCCCAGTAAC ATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGGACCAACTGCACAAATGCA TTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAGCCTCGGGTGCAATCCTGG AGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCTGGAGACCTTAAATTCAGC AAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCATGGCTTTTTCCCCACCAAC TTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAAGACAAGGAAGCAGACAAA GATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGAATGCTGGCAGACAAAATA GGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCTGTGCCAGGAGTTGATGCT GGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAAAAGCGGCACTCCTTCACT TCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTCCTCATCAGCTCCAGCAAC CCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAATATCAGGCATGTGTCTTA GGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGC AGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAA ACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGAT ACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCT TGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTC AGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAA TGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCT ATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGAT GAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTT GAAATCAATAAATTCTACATTTCTAATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAAC CTCACATATATTTTGTATAATTATTTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTT ATATTCCTTACACAAAAAGAAAATACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAA CAAACTTTGTAAATCTTCCATAAGCAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATT TAAAATAAATAAATTTTTAATGACCTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTA GACCTAGTTGAGTCAGGATAACAGAGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAAT AGTGGTGTTTTTACCTATGAAATTATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAA AAATTTAGTTGTTCTCCCCAATGTGTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTT TGCCTTTCTAGATTTCTTTATCTTTCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCA TATTTTTACAAAGTTTGTCATTTGCCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATT TAATCTTAGAATTATGTTATTTTTGTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATT TTAGCATGCATACCAATATAGTATATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATG AAGAAAATGGGATACGTTTGTTTCTTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTA AGATTTAACTGTAGCAAAAATTACTTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTT TAACTATATCATACCAATGGTTTTGTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTG GGTAAACTGGTTTCCCAGTATACAATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAA >In-frame_SH3RF1_ENST00000284637_chr4_170057469_-_SPOCK3_ENST00000506886_chr4_167810395_-_3771nt CGCCCCGGGCGCCGGCTGCGTCCCGGCCTCCTCCTCCTCTTCCTCCGCCCTCCTTGGCTGGGAAAGTGGGAGGCGGCGGCGGCGGCGTGG TGTGTGTGCGCGCGTGAGGGGGGCAGCAGAGAGGAGTCTCCCGGTGCCGCCGCGGCGTCAGAGACACTGCGAGCGGCGAGCGCGGTGGGG CCGCATCTGCATCAGCCGCCGCAGCCGCTGCGGGGCCGCGAACAAAGAGGAGGAGCCGAGGCGCGAGAGCAAAGTCTGAAATGGATGTTA CATGAGTCATTTTAAGGGATGCACACAACTATGAACATTTCTGAAGATTTTTTCTCAGTAAAGTAGATAAAGATGGATGAATCAGCCTTG TTGGATCTTTTGGAGTGTCCGGTGTGTCTAGAGCGCCTTGATGCTTCTGCGAAGGTCTTGCCTTGCCAGCATACGTTTTGCAAGCGATGT TTGCTGGGGATCGTAGGTTCTCGAAATGAACTCAGATGTCCCGAGTGCAGGACTCTTGTTGGCTCGGGTGTCGAGGAGCTTCCCAGTAAC ATCTTGCTGGTCAGACTTCTGGATGGCATCAAACAGAGGCCTTGGAAACCTGGTCCTGGTGGGGGAAGTGGGACCAACTGCACAAATGCA TTAAGGTCTCAGAGCAGCACTGTGGCTAATTGTAGCTCAAAAGATCTGCAGAGCTCCCAGGGCGGACAGCAGCCTCGGGTGCAATCCTGG AGCCCCCCAGTGAGGGGTATACCTCAGTTACCATGTGCCAAAGCATTATACAACTATGAAGGAAAAGAGCCTGGAGACCTTAAATTCAGC AAAGGTGACATCATCATTTTGCGAAGACAAGTGGATGAAAATTGGTACCATGGGGAAGTCAATGGAATCCATGGCTTTTTCCCCACCAAC TTTGTGCAGATTATTAAACCGTTACCTCAGCCCCCACCTCAGTGCAAAGCACTTTATGACTTTGAAGTGAAAGACAAGGAAGCAGACAAA GATTGCCTTCCATTTGCAAAGGATGATGTTCTGACTGTGATCCGAAGAGTGGATGAAAACTGGGCTGAAGGAATGCTGGCAGACAAAATA GGAATATTTCCAATTTCATATGTTGAGTTTAACTCGGCTGCTAAGCAGCTGATAGAATGGGATAAGCCTCCTGTGCCAGGAGTTGATGCT GGAGAATGTTCCTCGGCAGCAGCCCAGAGCAGCACTGCCCCAAAGCACTCCGACACCAAGAAGAACACCAAAAAGCGGCACTCCTTCACT TCCCTCACTATGGCCAACAAGTCCTCCCAGGCATCCCAGAACCGCCACTCCATGGAGATCAGCCCCCCTGTCCTCATCAGCTCCAGCAAC CCCACTGCTGCTGCACGGATCAGCGAGCTGTCTGGGCTCTCCTGCAGTGCCCCTTCTCAGTGCAAACTAGAATATCAGGCATGTGTCTTA GGAAAACAGATCTCAGTCAAATGTGAAGGACATTGCCCATGTCCTTCAGATAAGCCCACCAGTACAAGCAGAAATGTTAAGAGAGCATGC AGTGACCTGGAGTTCAGGGAAGTGGCAAACAGATTGCGGGACTGGTTCAAGGCCCTTCATGAAAGTGGAAGTCAAAACAAGAAGACAAAA ACATTGCTGAGGCCTGAGAGAAGCAGATTCGATACCAGCATCTTGCCAATTTGCAAGGACTCACTTGGCTGGATGTTTAACAGACTTGAT ACAAACTATGACCTGCTATTGGACCAGTCAGAGCTCAGAAGCATTTACCTTGATAAGAATGAACAGTGTACCAAGGCATTCTTCAATTCT TGTGACACATACAAGGACAGTTTAATATCTAATAATGAGTGGTGCTACTGCTTCCAGAGACAGCAAGACCCACCTTGCCAGACTGAGCTC AGCAATATTCAGAAGCGGCAAGGGGTAAAGAAGCTCCTAGGACAGTATATCCCCCTGTGTGATGAAGATGGTTACTACAAGCCAACACAA TGTCATGGCAGTGTTGGACAGTGCTGGTGTGTTGACAGATATGGAAATGAAGTCATGGGATCCAGAATAAATGGTGTTGCAGATTGTGCT ATAGATTTTGAGATCTCCGGAGATTTTGCTAGTGGCGATTTTCATGAATGGACTGATGATGAGGATGATGAAGACGATATTATGAATGAT GAAGATGAAATTGAAGATGATGATGAAGATGAAGGGGATGATGATGATGGTGGTGATGACCATGATGTATACATTTGATTGATGACAGTT GAAATCAATAAATTCTACATTTCTAATATTTACAAAAATGATAGCCTATTTAAAATTATCTTCTTCCCCAATAACAAAATGATTCTAAAC CTCACATATATTTTGTATAATTATTTGAAAAATTGCAGCTAAAGTTATAGAACTTTATGTTTAAATAAGAATCATTTGCTTTGAGTTTTT ATATTCCTTACACAAAAAGAAAATACATATGCAGTCTAGTCAGACAAAATAAAGTTTTGAAGTGCTACTATAATAAGTTTTTCACGAGAA CAAACTTTGTAAATCTTCCATAAGCAAAATGACAGCTAGTGCTTGGGATCGTACATGTTAATTTTCTGAAAGATAATTCTAAGTGAAATT TAAAATAAATAAATTTTTAATGACCTGGGTCTTAAGGATTTAGGAAAAATATGCATGCTTTAATTGCATTTCCAAAGTAGCATCTTGCTA GACCTAGTTGAGTCAGGATAACAGAGAGATACCACATGGCAAGAAAAACAAAGTGACAATTGTAGAGTCCTCAATTGTGTTTACATTAAT AGTGGTGTTTTTACCTATGAAATTATTCTGGATCTAATAGGACATTTTACAAAATGGCAAGTATGGAAAACCATGGATTCTGAAAGTTAA AAATTTAGTTGTTCTCCCCAATGTGTATTTTAATTTGGATGGCAGTCTCATGCAGATTTTTTAAAAGATTCTTTAATAACATGATTTGTT TGCCTTTCTAGATTTCTTTATCTTTCTGACCAGCAACTTAGGGAGCAGAATTTAAATTAGGAAGACAAAGGGAAAGATTCATTTAAACCA TATTTTTACAAAGTTTGTCATTTGCCCCAAGGTCAAATTTTAAATTCTTAATTTTCATTTTATTTCCCATTTTAGGTAAAAGTTTGCATT TAATCTTAGAATTATGTTATTTTTGTTAGTAGTGTGGAAACTTAGAGAACTTATTGTATGGTGCCTTGCAAAAATAGAGATAGAAAGATT TTAGCATGCATACCAATATAGTATATTACGCAATATATAAGCACACCTAATTAACAGATTAATATCAGTAAAGGTATTGCTGCTGGAATG AAGAAAATGGGATACGTTTGTTTCTTTTTTTCTATTGTTACATAATTGCCATGTGGACTTGTTTATGATTATTGTGTAGAGTAGCATTTA AGATTTAACTGTAGCAAAAATTACTTTAACCGCTGTATTTAAGTTAGCATGTTAATTAATTGTGTAGACATTTTGGCACACCATCACTTT TAACTATATCATACCAATGGTTTTGTGCCCATAATAAAAATGGAAAAACCTGTTGAATGTTACGTATTGGTATCTTTAATTTCAACAGTG GGTAAACTGGTTTCCCAGTATACAATTCATTGAAAGCAAAATTGATTAATTATTTCCATTTAATTTATACACACTCAATACAAAATTTAA |
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FusionGenePPI for SH3RF1_SPOCK3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SH3RF1 | AKT2, MAP3K11, MAP4K3, RAC1, PDCD6IP, KCNJ1, SEMA6A, SH3RF2, SIAH1, SIAH2, AKT1, UBE2N, UBE2D3, UBE2D1, YWHAB, NINL, HERPUD1, SH3RF1, FAT1, CDH1, TRIM25 | SPOCK3 | SPOCK2, MMP3, MMP14, CREB3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 440_543 | 356 | 889 | AKT2 |
| Hgene | SH3RF1 | chr4:170057469 | chr4:167810395 | ENST00000284637 | - | 5 | 12 | 292_362 | 356 | 889 | RAC1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SH3RF1_SPOCK3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SH3RF1_SPOCK3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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