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Fusion gene ID: 33442 |
FusionGeneSummary for SF3A1_PES1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SF3A1_PES1 | Fusion gene ID: 33442 | Hgene | Tgene | Gene symbol | SF3A1 | PES1 | Gene ID | 10291 | 23481 |
| Gene name | splicing factor 3a subunit 1 | pescadillo ribosomal biogenesis factor 1 | |
| Synonyms | PRP21|PRPF21|SAP114|SF3A120 | NOP7|PES | |
| Cytomap | 22q12.2 | 22q12.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | splicing factor 3A subunit 1SAP 114pre-mRNA processing 21pre-mRNA splicing factor SF3a (120 kDa subunit)spliceosome-associated protein 114splicing factor 3 subunit 1splicing factor 3a, subunit 1, 120kDsplicing factor 3a, subunit 1, 120kDa | pescadillo homologpescadillo homolog 1, containing BRCT domain | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q15459 | O00541 | |
| Ensembl transtripts involved in fusion gene | ENST00000215793, ENST00000439242, | ENST00000354694, ENST00000402281, ENST00000405677, ENST00000402284, ENST00000335214, ENST00000492986, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 4 X 4 X 3=48 |
| # samples | 4 | 4 | |
| ** MAII score | log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SF3A1 [Title/Abstract] AND PES1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SF3A1 | GO:0000398 | mRNA splicing, via spliceosome | 10882114 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | UCEC | TCGA-AJ-A3BD-01A | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000215793 | ENST00000354694 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| Frame-shift | ENST00000215793 | ENST00000402281 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| In-frame | ENST00000215793 | ENST00000405677 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| In-frame | ENST00000215793 | ENST00000402284 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| Frame-shift | ENST00000215793 | ENST00000335214 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| 5CDS-intron | ENST00000215793 | ENST00000492986 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| In-frame | ENST00000439242 | ENST00000354694 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| Frame-shift | ENST00000439242 | ENST00000402281 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| In-frame | ENST00000439242 | ENST00000405677 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| In-frame | ENST00000439242 | ENST00000402284 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| Frame-shift | ENST00000439242 | ENST00000335214 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
| 5CDS-intron | ENST00000439242 | ENST00000492986 | SF3A1 | chr22 | 30733015 | - | PES1 | chr22 | 30973116 | - |
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FusionProtFeatures for SF3A1_PES1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SF3A1 | PES1 |
| Subunit of the splicing factor SF3A required for 'A'complex assembly formed by the stable binding of U2 snRNP to thebranchpoint sequence (BPS) in pre-mRNA. Sequence independentbinding of SF3A/SF3B complex upstream of the branch site isessential, it may anchor U2 snRNP to the pre-mRNA. May also beinvolved in the assembly of the 'E' complex. | Component of the PeBoW complex, which is required formaturation of 28S and 5.8S ribosomal RNAs and formation of the 60Sribosome. {ECO:0000255|HAMAP-Rule:MF_03028,ECO:0000269|PubMed:16738141, ECO:0000269|PubMed:17189298,ECO:0000269|PubMed:17353269}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 10_16 | 702 | 794 | Compositional bias | Note=Poly-Pro |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 118_122 | 702 | 794 | Compositional bias | Note=Poly-Gln |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 260_267 | 702 | 794 | Compositional bias | Note=Poly-Glu |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 369_372 | 702 | 794 | Compositional bias | Note=Poly-Pro |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 557_560 | 702 | 794 | Compositional bias | Note=Poly-Pro |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 672_675 | 702 | 794 | Compositional bias | Note=Poly-Pro |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 166_208 | 702 | 794 | Repeat | Note=SURP motif 2 |
| Hgene | SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 52_94 | 702 | 794 | Repeat | Note=SURP motif 1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SF3A1 | chr22:30733015 | chr22:30973116 | ENST00000215793 | - | 13 | 16 | 707_793 | 702 | 794 | Domain | Ubiquitin-like |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000335214 | - | 13 | 15 | 456_531 | 556 | 584 | Compositional bias | Note=Glu-rich |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000354694 | - | 13 | 15 | 456_531 | 561 | 589 | Compositional bias | Note=Glu-rich |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000335214 | - | 13 | 15 | 322_415 | 556 | 584 | Domain | BRCT |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000354694 | - | 13 | 15 | 322_415 | 561 | 589 | Domain | BRCT |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000335214 | - | 13 | 15 | 1_257 | 556 | 584 | Region | Note=Sufficient for nucleolar localization |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000335214 | - | 13 | 15 | 1_54 | 556 | 584 | Region | Note=Required for 28S ribosomal RNA processing |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000335214 | - | 13 | 15 | 539_588 | 556 | 584 | Region | Note=Required for 28S ribosomal RNA processing |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000354694 | - | 13 | 15 | 1_257 | 561 | 589 | Region | Note=Sufficient for nucleolar localization |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000354694 | - | 13 | 15 | 1_54 | 561 | 589 | Region | Note=Required for 28S ribosomal RNA processing |
| Tgene | PES1 | chr22:30733015 | chr22:30973116 | ENST00000354694 | - | 13 | 15 | 539_588 | 561 | 589 | Region | Note=Required for 28S ribosomal RNA processing |
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FusionGeneSequence for SF3A1_PES1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000354694_chr22_30973116_-_730aa MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPY HAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVA YAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQ SDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVP MPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKANKLAEKRKAHDEAVRSE >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000405677_chr22_30973116_-_730aa MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPY HAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVA YAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQ SDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVP MPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKANKLAEKRKAHDEAVRSE >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000402284_chr22_30973116_-_730aa MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPY HAYYRHKVSEFKEGKAQEPSAAIPKVMQQQQQTTQQQLPQKVQAQVIQETIVPKEPPPEFEFIADPPSISAFDLDVVKLTAQFVARNGRQ FLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCYRVEWAKFQERERKKEEEEKEKERVA YAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDKQEKAEEPPSQLDQDTQVQDMDEGSD DEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKMQEHMRIGLLDPRWLEQRDRSIREKQ SDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQAAQANITLQEQIEAIHKAKGLVPEDD TKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASVVRLPPGSVIAPMPPIIHAPRINVVP MPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEEEFLRRNKANKLAEKRKAHDEAVRSE >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000354694_chr22_30973116_-_665aa MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPY HAYYRHKVSEFKEGKAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCY RVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDK QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM QEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQA AQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000405677_chr22_30973116_-_665aa MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPY HAYYRHKVSEFKEGKAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCY RVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDK QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM QEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQA AQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000402284_chr22_30973116_-_665aa MPAGPVQAVPPPPPVPTEPKQPTEEEASSKEDSAPSKPVVGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQNEINNPKFNFLNPNDPY HAYYRHKVSEFKEGKAQFVARNGRQFLTQLMQKEQRNYQFDFLRPQHSLFNYFTKLVEQYTKILIPPKGLFSKLKKEAENPREVLDQVCY RVEWAKFQERERKKEEEEKEKERVAYAQIDWHDFVVVETVDFQPNEQGNFPPPTTPEELGARILIQERYEKFGESEEVEMEVESDEEDDK QEKAEEPPSQLDQDTQVQDMDEGSDDEEEGQKVPPPPETPMPPPLPPTPDQVIVRKDYDPKASKPLPPAPAPDEYLVSPITGEKIPASKM QEHMRIGLLDPRWLEQRDRSIREKQSDDEVYAPGLDIESSLKQLAERRTDIFGVEETAIGKKIGEEEIQKPEEKVTWDGHSGSMARTQQA AQANITLQEQIEAIHKAKGLVPEDDTKEKIGPSKPNEIPQQPPPPSSATNIPSSAPPITSVPRPPTMPPPVRTTVVSAVPVMPRPPMASV VRLPPGSVIAPMPPIIHAPRINVVPMPPSAPPIMAPRPPPMIVPTAFVPAPPVAPVPAPAPMPPVHPPPPMEDEPTSKKLKTEDSLMPEE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000354694_chr22_30973116_-_2190nt ATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAG GAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTG GCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTAC CATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCTCAGGAGCCGTCCGCCGCCATCCCCAAGGTCATGCAGCAGCAG CAGCAGACCACCCAGCAGCAGCTGCCCCAGAAGGTCCAAGCCCAAGTAATCCAAGAGACCATCGTGCCCAAAGAGCCTCCTCCTGAGTTT GAGTTCATTGCTGATCCTCCCTCTATCTCAGCCTTCGACTTGGATGTGGTGAAGCTGACGGCTCAGTTTGTGGCCAGGAATGGGCGCCAG TTTCTGACCCAGCTGATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAG CTAGTGGAACAGTACACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTG GATCAGGTGTGTTACCGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCC TATGCTCAGATCGACTGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACG CCAGAGGAGCTGGGGGCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGAT GAGGAGGATGACAAACAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGAT GATGAAGAAGAAGGGCAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGC AAGGATTATGATCCCAAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATC CCCGCCAGCAAAATGCAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAG AGCGATGATGAGGTGTACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAG GAAACAGCCATTGGTAAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCC CGGACCCAGCAGGCTGCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGAC ACTAAAGAGAAGATTGGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCT CCACCCATCACTTCAGTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCC CCAATGGCATCTGTGGTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCC ATGCCTCCCTCGGCCCCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCT GTCCCAGCTCCAGCCCCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGC CTCATGCCAGAGGAGGAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAG >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000405677_chr22_30973116_-_2190nt ATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAG GAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTG GCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTAC CATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCTCAGGAGCCGTCCGCCGCCATCCCCAAGGTCATGCAGCAGCAG CAGCAGACCACCCAGCAGCAGCTGCCCCAGAAGGTCCAAGCCCAAGTAATCCAAGAGACCATCGTGCCCAAAGAGCCTCCTCCTGAGTTT GAGTTCATTGCTGATCCTCCCTCTATCTCAGCCTTCGACTTGGATGTGGTGAAGCTGACGGCTCAGTTTGTGGCCAGGAATGGGCGCCAG TTTCTGACCCAGCTGATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAG CTAGTGGAACAGTACACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTG GATCAGGTGTGTTACCGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCC TATGCTCAGATCGACTGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACG CCAGAGGAGCTGGGGGCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGAT GAGGAGGATGACAAACAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGAT GATGAAGAAGAAGGGCAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGC AAGGATTATGATCCCAAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATC CCCGCCAGCAAAATGCAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAG AGCGATGATGAGGTGTACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAG GAAACAGCCATTGGTAAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCC CGGACCCAGCAGGCTGCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGAC ACTAAAGAGAAGATTGGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCT CCACCCATCACTTCAGTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCC CCAATGGCATCTGTGGTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCC ATGCCTCCCTCGGCCCCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCT GTCCCAGCTCCAGCCCCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGC CTCATGCCAGAGGAGGAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAG >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000402284_chr22_30973116_-_2190nt ATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAG GAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTG GCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTAC CATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCTCAGGAGCCGTCCGCCGCCATCCCCAAGGTCATGCAGCAGCAG CAGCAGACCACCCAGCAGCAGCTGCCCCAGAAGGTCCAAGCCCAAGTAATCCAAGAGACCATCGTGCCCAAAGAGCCTCCTCCTGAGTTT GAGTTCATTGCTGATCCTCCCTCTATCTCAGCCTTCGACTTGGATGTGGTGAAGCTGACGGCTCAGTTTGTGGCCAGGAATGGGCGCCAG TTTCTGACCCAGCTGATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAG CTAGTGGAACAGTACACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTG GATCAGGTGTGTTACCGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCC TATGCTCAGATCGACTGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACG CCAGAGGAGCTGGGGGCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGAT GAGGAGGATGACAAACAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGAT GATGAAGAAGAAGGGCAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGC AAGGATTATGATCCCAAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATC CCCGCCAGCAAAATGCAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAG AGCGATGATGAGGTGTACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAG GAAACAGCCATTGGTAAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCC CGGACCCAGCAGGCTGCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGAC ACTAAAGAGAAGATTGGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCT CCACCCATCACTTCAGTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCC CCAATGGCATCTGTGGTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCC ATGCCTCCCTCGGCCCCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCT GTCCCAGCTCCAGCCCCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGC CTCATGCCAGAGGAGGAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAG >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000354694_chr22_30973116_-_1995nt ATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAG GAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTG GCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTAC CATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCTCAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTG ATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTAC ACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTAC CGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGAC TGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGG GCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAA CAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGG CAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCC AAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATG CAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTG TACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGT AAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCT GCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATT GGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCA GTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTG GTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCC CCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCC CCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAG GAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAG >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000405677_chr22_30973116_-_1995nt ATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAG GAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTG GCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTAC CATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCTCAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTG ATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTAC ACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTAC CGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGAC TGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGG GCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAA CAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGG CAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCC AAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATG CAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTG TACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGT AAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCT GCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATT GGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCA GTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTG GTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCC CCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCC CCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAG GAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAG >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000402284_chr22_30973116_-_1995nt ATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAG GAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTG GCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTAC CATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCTCAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTG ATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTAC ACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTAC CGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGAC TGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGG GCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAA CAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGG CAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCC AAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATG CAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTG TACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGT AAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCT GCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATT GGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCA GTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTG GTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCC CCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCC CCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAG GAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000354694_chr22_30973116_-_2766nt GGTCCCGGAAGTGCGCCAGTCGTACCTTCGCGGCCGCAACTCGCTCGGCCGCCGCCATCTTGCGAGCTCGTCGTACTGACCGAGCGGGGA GGCTGTCTTGAGGCGGCACCGCTCACCGACACCGAGGCGGACTGGCAGCCCTGAGCGTCGCAGTCATGCCGGCCGGACCCGTGCAGGCGG TGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAGGAGGATTCTGCACCTTCTAAGCCAG TTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTGGCCAGAAACGGGCCTGAATTTGAAG CTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTACCATGCCTACTACCGCCACAAGGTCA GCGAGTTCAAGGAAGGGAAGGCTCAGGAGCCGTCCGCCGCCATCCCCAAGGTCATGCAGCAGCAGCAGCAGACCACCCAGCAGCAGCTGC CCCAGAAGGTCCAAGCCCAAGTAATCCAAGAGACCATCGTGCCCAAAGAGCCTCCTCCTGAGTTTGAGTTCATTGCTGATCCTCCCTCTA TCTCAGCCTTCGACTTGGATGTGGTGAAGCTGACGGCTCAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTGATGCAGAAAG AGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTACACCAAGATCT TGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTACCGAGTGGAAT GGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGACTGGCATGATT TTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGGGCCCGAATCC TCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAACAGGAGAAGG CGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGGCAGAAAGTGC CCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCCAAAGCCTCCA AGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATGCAGGAACACA TGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTGTACGCACCAG GTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGTAAGAAGATCG GTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCTGCCCAGGCCA ACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATTGGCCCCAGCA AGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCAGTGCCCCGAC CACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTGGTCCGGCTGC CCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCCCCTCCTATTA TGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCCCCAATGCCCC CTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAGGAGTTCCTGC GCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAGGCAAGGCCGG AGTGAGTGCCTGCGGCCCCTCACAGGGCTGAGGCCAGCCCCTAGCAGCTGGATGTGGCAGAGGCAGGCCAGAGGACCTAAGTGTGATGGA CCAGAGTCACTTCTCCTCCTCCTTTCTCCAGCCAGCCCTGACCCCTCATGCTCTCTGGCTGGGCCAGTGGGCAGCCCTCGCTTCCCTTGG ATGGAGCTGCCCTGCTGGTGCCTGGTCAGAGAAGAGGCCTCTGTGCCCAGCCTGATTCTCTGCTCCCAGGAGCCAGTGACATGAGGTGCA GAGGCCCACCCAGCCCCCTACCTACTGCCCCCATTCATCCTGGCTTTCCACAGCCCCCTCCCACACAGTTGGACCCGTGATTCTCAGGGT >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000405677_chr22_30973116_-_2759nt GGTCCCGGAAGTGCGCCAGTCGTACCTTCGCGGCCGCAACTCGCTCGGCCGCCGCCATCTTGCGAGCTCGTCGTACTGACCGAGCGGGGA GGCTGTCTTGAGGCGGCACCGCTCACCGACACCGAGGCGGACTGGCAGCCCTGAGCGTCGCAGTCATGCCGGCCGGACCCGTGCAGGCGG TGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAGGAGGATTCTGCACCTTCTAAGCCAG TTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTGGCCAGAAACGGGCCTGAATTTGAAG CTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTACCATGCCTACTACCGCCACAAGGTCA GCGAGTTCAAGGAAGGGAAGGCTCAGGAGCCGTCCGCCGCCATCCCCAAGGTCATGCAGCAGCAGCAGCAGACCACCCAGCAGCAGCTGC CCCAGAAGGTCCAAGCCCAAGTAATCCAAGAGACCATCGTGCCCAAAGAGCCTCCTCCTGAGTTTGAGTTCATTGCTGATCCTCCCTCTA TCTCAGCCTTCGACTTGGATGTGGTGAAGCTGACGGCTCAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTGATGCAGAAAG AGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTACACCAAGATCT TGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTACCGAGTGGAAT GGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGACTGGCATGATT TTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGGGCCCGAATCC TCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAACAGGAGAAGG CGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGGCAGAAAGTGC CCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCCAAAGCCTCCA AGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATGCAGGAACACA TGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTGTACGCACCAG GTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGTAAGAAGATCG GTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCTGCCCAGGCCA ACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATTGGCCCCAGCA AGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCAGTGCCCCGAC CACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTGGTCCGGCTGC CCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCCCCTCCTATTA TGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCCCCAATGCCCC CTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAGGAGTTCCTGC GCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAGGCAAGGCCGG AGTGAGTGCCTGCGGCCCCTCACAGGGCTGAGGCCAGCCCCTAGCAGCTGGATGTGGCAGAGGCAGGCCAGAGGACCTAAGTGTGATGGA CCAGAGTCACTTCTCCTCCTCCTTTCTCCAGCCAGCCCTGACCCCTCATGCTCTCTGGCTGGGCCAGTGGGCAGCCCTCGCTTCCCTTGG ATGGAGCTGCCCTGCTGGTGCCTGGTCAGAGAAGAGGCCTCTGTGCCCAGCCTGATTCTCTGCTCCCAGGAGCCAGTGACATGAGGTGCA GAGGCCCACCCAGCCCCCTACCTACTGCCCCCATTCATCCTGGCTTTCCACAGCCCCCTCCCACACAGTTGGACCCGTGATTCTCAGGGT >In-frame_SF3A1_ENST00000215793_chr22_30733015_-_PES1_ENST00000402284_chr22_30973116_-_2726nt GGTCCCGGAAGTGCGCCAGTCGTACCTTCGCGGCCGCAACTCGCTCGGCCGCCGCCATCTTGCGAGCTCGTCGTACTGACCGAGCGGGGA GGCTGTCTTGAGGCGGCACCGCTCACCGACACCGAGGCGGACTGGCAGCCCTGAGCGTCGCAGTCATGCCGGCCGGACCCGTGCAGGCGG TGCCCCCGCCGCCGCCCGTGCCCACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAGGAGGATTCTGCACCTTCTAAGCCAG TTGTGGGGATTATTTACCCTCCTCCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTGGCCAGAAACGGGCCTGAATTTGAAG CTAGGATCCGACAGAACGAGATCAACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTACCATGCCTACTACCGCCACAAGGTCA GCGAGTTCAAGGAAGGGAAGGCTCAGGAGCCGTCCGCCGCCATCCCCAAGGTCATGCAGCAGCAGCAGCAGACCACCCAGCAGCAGCTGC CCCAGAAGGTCCAAGCCCAAGTAATCCAAGAGACCATCGTGCCCAAAGAGCCTCCTCCTGAGTTTGAGTTCATTGCTGATCCTCCCTCTA TCTCAGCCTTCGACTTGGATGTGGTGAAGCTGACGGCTCAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTGATGCAGAAAG AGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAGCACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTACACCAAGATCT TGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAAGAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTACCGAGTGGAAT GGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAAGAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGACTGGCATGATT TTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAGCAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGGGCCCGAATCC TCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAGGAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAACAGGAGAAGG CGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAAGTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGGCAGAAAGTGC CCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCCCCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCCAAAGCCTCCA AGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTTGTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATGCAGGAACACA TGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAGCGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTGTACGCACCAG GTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAGCGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGTAAGAAGATCG GTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACCTGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCTGCCCAGGCCA ACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAGGCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATTGGCCCCAGCA AGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCTTCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCAGTGCCCCGAC CACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTCTCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTGGTCCGGCTGC CCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATCCACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCCCCTCCTATTA TGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCCTTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCCCCAATGCCCC CTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACCTCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAGGAGTTCCTGC GCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAAGCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAGGCAAGGCCGG AGTGAGTGCCTGCGGCCCCTCACAGGGCTGAGGCCAGCCCCTAGCAGCTGGATGTGGCAGAGGCAGGCCAGAGGACCTAAGTGTGATGGA CCAGAGTCACTTCTCCTCCTCCTTTCTCCAGCCAGCCCTGACCCCTCATGCTCTCTGGCTGGGCCAGTGGGCAGCCCTCGCTTCCCTTGG ATGGAGCTGCCCTGCTGGTGCCTGGTCAGAGAAGAGGCCTCTGTGCCCAGCCTGATTCTCTGCTCCCAGGAGCCAGTGACATGAGGTGCA GAGGCCCACCCAGCCCCCTACCTACTGCCCCCATTCATCCTGGCTTTCCACAGCCCCCTCCCACACAGTTGGACCCGTGATTCTCAGGGT >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000354694_chr22_30973116_-_2548nt ACCTTCGCGGCCGCAACTCGCTCGGCCGCCGCCATCTTGCGAGCTCGTCGTACTGACCGAGCGGGGAGGCTGTCTTGAGGCGGCACCGCT CACCGACACCGAGGCGGACTGGCAGCCCTGAGCGTCGCAGTCATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCC ACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAGGAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCT CCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTGGCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATC AACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTACCATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCT CAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTGATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAG CACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTACACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAA GAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTACCGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAA GAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGACTGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAG CAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGGGCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAG GAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAACAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAA GTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGGCAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCC CCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCCAAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTT GTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATGCAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAG CGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTGTACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAG CGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGTAAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACC TGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCTGCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAG GCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATTGGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCT TCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCAGTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTC TCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTGGTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATC CACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCCCCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCC TTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCCCCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACC TCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAGGAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAA GCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAGGCAAGGCCGGAGTGAGTGCCTGCGGCCCCTCACAGGGCTGAGGCCAGC CCCTAGCAGCTGGATGTGGCAGAGGCAGGCCAGAGGACCTAAGTGTGATGGACCAGAGTCACTTCTCCTCCTCCTTTCTCCAGCCAGCCC TGACCCCTCATGCTCTCTGGCTGGGCCAGTGGGCAGCCCTCGCTTCCCTTGGATGGAGCTGCCCTGCTGGTGCCTGGTCAGAGAAGAGGC CTCTGTGCCCAGCCTGATTCTCTGCTCCCAGGAGCCAGTGACATGAGGTGCAGAGGCCCACCCAGCCCCCTACCTACTGCCCCCATTCAT CCTGGCTTTCCACAGCCCCCTCCCACACAGTTGGACCCGTGATTCTCAGGGTGCTGTGATGGGGTGAGGGTAGGGGGAGCATTTGTTATT >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000405677_chr22_30973116_-_2541nt ACCTTCGCGGCCGCAACTCGCTCGGCCGCCGCCATCTTGCGAGCTCGTCGTACTGACCGAGCGGGGAGGCTGTCTTGAGGCGGCACCGCT CACCGACACCGAGGCGGACTGGCAGCCCTGAGCGTCGCAGTCATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCC ACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAGGAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCT CCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTGGCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATC AACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTACCATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCT CAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTGATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAG CACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTACACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAA GAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTACCGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAA GAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGACTGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAG CAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGGGCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAG GAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAACAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAA GTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGGCAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCC CCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCCAAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTT GTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATGCAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAG CGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTGTACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAG CGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGTAAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACC TGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCTGCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAG GCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATTGGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCT TCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCAGTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTC TCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTGGTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATC CACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCCCCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCC TTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCCCCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACC TCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAGGAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAA GCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAGGCAAGGCCGGAGTGAGTGCCTGCGGCCCCTCACAGGGCTGAGGCCAGC CCCTAGCAGCTGGATGTGGCAGAGGCAGGCCAGAGGACCTAAGTGTGATGGACCAGAGTCACTTCTCCTCCTCCTTTCTCCAGCCAGCCC TGACCCCTCATGCTCTCTGGCTGGGCCAGTGGGCAGCCCTCGCTTCCCTTGGATGGAGCTGCCCTGCTGGTGCCTGGTCAGAGAAGAGGC CTCTGTGCCCAGCCTGATTCTCTGCTCCCAGGAGCCAGTGACATGAGGTGCAGAGGCCCACCCAGCCCCCTACCTACTGCCCCCATTCAT CCTGGCTTTCCACAGCCCCCTCCCACACAGTTGGACCCGTGATTCTCAGGGTGCTGTGATGGGGTGAGGGTAGGGGGAGCATTTGTTATT >In-frame_SF3A1_ENST00000439242_chr22_30733015_-_PES1_ENST00000402284_chr22_30973116_-_2508nt ACCTTCGCGGCCGCAACTCGCTCGGCCGCCGCCATCTTGCGAGCTCGTCGTACTGACCGAGCGGGGAGGCTGTCTTGAGGCGGCACCGCT CACCGACACCGAGGCGGACTGGCAGCCCTGAGCGTCGCAGTCATGCCGGCCGGACCCGTGCAGGCGGTGCCCCCGCCGCCGCCCGTGCCC ACGGAGCCCAAACAGCCCACAGAAGAAGAAGCATCTTCAAAGGAGGATTCTGCACCTTCTAAGCCAGTTGTGGGGATTATTTACCCTCCT CCAGAGGTCAGAAATATTGTTGACAAGACTGCCAGCTTTGTGGCCAGAAACGGGCCTGAATTTGAAGCTAGGATCCGACAGAACGAGATC AACAACCCCAAGTTCAACTTTCTGAACCCCAATGACCCTTACCATGCCTACTACCGCCACAAGGTCAGCGAGTTCAAGGAAGGGAAGGCT CAGTTTGTGGCCAGGAATGGGCGCCAGTTTCTGACCCAGCTGATGCAGAAAGAGCAGCGCAACTACCAGTTTGACTTTCTCCGCCCACAG CACAGCCTCTTCAACTACTTCACGAAGCTAGTGGAACAGTACACCAAGATCTTGATTCCACCCAAAGGTTTATTTTCAAAGCTCAAGAAA GAGGCTGAAAACCCCCGAGAAGTTTTGGATCAGGTGTGTTACCGAGTGGAATGGGCCAAATTCCAGGAACGTGAGAGGAAGAAGGAAGAA GAGGAGAAGGAGAAGGAGCGGGTGGCCTATGCTCAGATCGACTGGCATGATTTTGTGGTGGTGGAAACAGTGGACTTCCAACCCAATGAG CAAGGGAACTTCCCTCCCCCCACCACGCCAGAGGAGCTGGGGGCCCGAATCCTCATTCAGGAGCGCTATGAAAAGTTTGGGGAGAGTGAG GAAGTTGAGATGGAGGTCGAGTCTGATGAGGAGGATGACAAACAGGAGAAGGCGGAGGAGCCTCCTTCCCAGCTGGACCAGGACACCCAA GTACAAGATATGGATGAGGGTTCAGATGATGAAGAAGAAGGGCAGAAAGTGCCCCCACCCCCAGAGACACCCATGCCTCCACCTCTGCCC CCAACTCCAGACCAAGTCATTGTCCGCAAGGATTATGATCCCAAAGCCTCCAAGCCCTTGCCTCCAGCCCCTGCTCCAGATGAGTATCTT GTGTCCCCCATTACTGGGGAGAAGATCCCCGCCAGCAAAATGCAGGAACACATGCGCATTGGACTTCTTGACCCTCGCTGGCTGGAGCAG CGGGATCGCTCCATCCGTGAGAAGCAGAGCGATGATGAGGTGTACGCACCAGGTCTGGATATTGAGAGCAGCTTGAAGCAGTTGGCTGAG CGGCGTACTGACATCTTCGGTGTAGAGGAAACAGCCATTGGTAAGAAGATCGGTGAGGAGGAGATCCAGAAGCCAGAGGAAAAGGTGACC TGGGATGGCCACTCAGGCAGCATGGCCCGGACCCAGCAGGCTGCCCAGGCCAACATCACCCTCCAGGAGCAGATTGAGGCCATTCACAAG GCCAAAGGCCTGGTGCCAGAGGATGACACTAAAGAGAAGATTGGCCCCAGCAAGCCCAATGAAATCCCTCAACAGCCACCGCCACCATCT TCAGCCACCAACATCCCCAGCTCGGCTCCACCCATCACTTCAGTGCCCCGACCACCCACAATGCCACCTCCAGTTCGTACTACAGTTGTC TCCGCAGTACCCGTCATGCCCCGGCCCCCAATGGCATCTGTGGTCCGGCTGCCCCCAGGCTCAGTGATCGCCCCCATGCCGCCCATCATC CACGCGCCCAGAATCAACGTGGTGCCCATGCCTCCCTCGGCCCCTCCTATTATGGCCCCCCGCCCACCCCCCATGATTGTGCCAACAGCC TTTGTGCCTGCTCCACCTGTGGCACCTGTCCCAGCTCCAGCCCCAATGCCCCCTGTGCATCCCCCACCTCCCATGGAAGATGAGCCCACC TCCAAAAAACTGAAGACAGAGGACAGCCTCATGCCAGAGGAGGAGTTCCTGCGCAGAAACAAGGCCAACAAGCTGGCGGAGAAGCGGAAA GCCCACGATGAGGCGGTGAGGTCTGAGAAGAAGGCCAAGAAGGCAAGGCCGGAGTGAGTGCCTGCGGCCCCTCACAGGGCTGAGGCCAGC CCCTAGCAGCTGGATGTGGCAGAGGCAGGCCAGAGGACCTAAGTGTGATGGACCAGAGTCACTTCTCCTCCTCCTTTCTCCAGCCAGCCC TGACCCCTCATGCTCTCTGGCTGGGCCAGTGGGCAGCCCTCGCTTCCCTTGGATGGAGCTGCCCTGCTGGTGCCTGGTCAGAGAAGAGGC CTCTGTGCCCAGCCTGATTCTCTGCTCCCAGGAGCCAGTGACATGAGGTGCAGAGGCCCACCCAGCCCCCTACCTACTGCCCCCATTCAT |
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FusionGenePPI for SF3A1_PES1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SF3A1 | TCERG1, ATG12, NCOR1, SF3A3, SF3A2, CDC5L, USP30, RAE1, TCEA1, MAP1LC3C, HDAC5, SIRT7, CUL3, CAND1, SF3B3, SNRPA1, SF3B1, SNRPD2, SF3B4, SNRPD1, SNRPB2, RBMX, SNRPA, SRSF1, SRSF5, SRSF7, PRPF8, SNRNP200, U2AF1, HNRNPR, HNRNPU, HNRNPM, DHX15, HNRNPC, HNRNPK, PRPF19, PRPF31, SART1, DDX5, USP39, PRPF3, DDX17, SRRM2, ACIN1, SKIV2L2, PLRG1, XAB2, MCM4, MCM7, SFPQ, MCM6, DYNC1H1, TRA2A, PSMD1, TRIM55, TPBG, ZNF326, RBM14, UTP14A, PSMA6, PSMB3, SSBP1, TSKS, PSMC1, THRAP3, PATL1, SUPT16H, VTN, ZC3H18, PSMB1, TOX4, RBM12B, PSMA5, VASN, PSMD7, TRMT112, SRP54, MDC1, MAGOH, EIF4A3, SMURF1, PRPF40A, RBM10, SF1, DDX42, WDR77, RBFOX2, CSNK2A1, IL7R, HDAC6, HDAC11, WBP4, APBB1, GAS7, WWOX, BRCC3, CCDC6, GAPVD1, HDAC1, NR3C1, PPP4R2, SMEK1, RPA3, RPA2, RPA1, ZBTB1, HUWE1, FUS, ENO1, MOV10, NXF1, CUL7, OBSL1, SUZ12, EED, RNF2, ABCE1, SERPINB5, RBM7, ZMAT3, RALYL, QPRT, LUC7L2, ACTL6A, ZRSR2, CYP1A1, ACTR1A, DDX46, EIF4G1, EPB41, GTF2F1, MCM5, PRPF6, FNBP1, FNBP1L, ISY1-RAB43, ISY1, PABPC1, PRPF4, TRIP10, SMARCC1, SMARCC2, U2SURP, ZNF830, NTRK1, SCARNA22, HIST1H3E, XRCC3, EMC2, ENTHD2, FOXQ1, SNW1, U2AF2, CCDC97, SNRPE, RBM17, SNRPG, HSPA8, SNRPN, CTSH, GM2A, C11orf57, CALML3, FGB, SNRPF, CST6, GTF2E2, TRMT2A, SNRNP27, MCM2, PA2G4, TRAP1, SND1, ANXA5, UBE2N, CYLD, CD2BP2, BRCA1 | PES1 | ARRB1, ARRB2, MYC, SIRT7, CUL3, CAND1, WDR12, BOP1, NAP1L1, NOC4L, NAP1L4, PES1, HDAC11, ARL2, LZTFL1, BLMH, MOV10, NXF1, CUL7, OBSL1, RNF2, MAGEA10, NIFK, PRR11, CASQ2, BRIX1, CEBPZ, FBL, FTSJ3, GNL1, GNL3, GTPBP4, KRR1, NHP2L1, NIP7, NOC2L, NOP2, NSA2, DDX24, DDX27, DHX15, EBNA1BP2, GNL3L, KIAA0020, MRTO4, NOC3L, NOP56, ORC2, RBM28, RPL18A, RPL31, RPL38, RPL4, RPL7A, RPL8, SUPT16H, PWP1, RPF2, RPL23, RPL27, RPL27A, RPL7, UBA52, UTP14A, NTRK1, SCARNA22, APP, IFI16, TP53, FOXL2, FOXM1, MYBBP1A, G3BP1, RRP12, RRBP1, DKC1, C1orf35, PRPF40A, TOP1, ZC3HAV1, KIF2A, TCEB3, PDIA3, SART1, MYH9, BUB3, DDX18, RPL7L1, RRS1, RRP1B, POP1, IGKC, CDC14B, BRD2, PFKFB3, NAF1, CWC22, UBTF, TRIM26, TNRC18, SETD1A, AFF4, CXXC1, MLLT3, CENPB, KLHL23, PNN, CSNK2A1, NVL, PPIL4, INPP5K, RNPS1, C18orf25, CCDC91, WDR55, SRRM2, AP3B1, KBTBD7, RPL36, NCL |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SF3A1_PES1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SF3A1_PES1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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