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Fusion gene ID: 33435 |
FusionGeneSummary for SF1_HRASLS2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SF1_HRASLS2 | Fusion gene ID: 33435 | Hgene | Tgene | Gene symbol | SF1 | HRASLS2 | Gene ID | 7536 | 54979 |
| Gene name | splicing factor 1 | HRAS like suppressor 2 | |
| Synonyms | BBP|D11S636|MBBP|ZCCHC25|ZFM1|ZNF162 | PLA1/2-2 | |
| Cytomap | 11q13.1 | 11q12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | splicing factor 1mammalian branch point-binding proteintranscription factor ZFM1zinc finger gene in MEN1 locuszinc finger protein 162 | HRAS-like suppressor 2 | |
| Modification date | 20180526 | 20180329 | |
| UniProtAcc | Q15637 | Q9NWW9 | |
| Ensembl transtripts involved in fusion gene | ENST00000377387, ENST00000377390, ENST00000377394, ENST00000227503, ENST00000334944, ENST00000422298, ENST00000433274, ENST00000489544, | ENST00000255695, | |
| Fusion gene scores | * DoF score | 9 X 6 X 7=378 | 2 X 2 X 2=8 |
| # samples | 9 | 2 | |
| ** MAII score | log2(9/378*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: SF1 [Title/Abstract] AND HRASLS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | HNSC | TCGA-BB-8596-01A | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000377387 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| In-frame | ENST00000377390 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| Frame-shift | ENST00000377394 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| In-frame | ENST00000227503 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| In-frame | ENST00000334944 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| In-frame | ENST00000422298 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| Frame-shift | ENST00000433274 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
| intron-3CDS | ENST00000489544 | ENST00000255695 | SF1 | chr11 | 64534372 | - | HRASLS2 | chr11 | 63326132 | - |
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FusionProtFeatures for SF1_HRASLS2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SF1 | HRASLS2 |
| Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in variousphosphatidylcholines (PC) and phosphatidylethanolamine (PE). Formost substrates, PLA1 activity is much higher than PLA2 activity.Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoylgroups of PC as acyl donor. Also catalyzes O-acylation convertinglyso-PC into PC. {ECO:0000269|PubMed:19615464,ECO:0000269|PubMed:22605381}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377387 | - | 12 | 13 | 324_637 | 652 | 674 | Compositional bias | Note=Pro-rich |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000227503 | - | 12 | 13 | 141_222 | 527 | 549 | Domain | KH |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000334944 | - | 12 | 14 | 141_222 | 527 | 639 | Domain | KH |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377387 | - | 12 | 13 | 141_222 | 652 | 674 | Domain | KH |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377390 | - | 12 | 13 | 141_222 | 527 | 640 | Domain | KH |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377394 | - | 12 | 13 | 141_222 | 528 | 572 | Domain | KH |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000433274 | - | 12 | 13 | 141_222 | 501 | 614 | Domain | KH |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000227503 | - | 12 | 13 | 15_19 | 527 | 549 | Motif | Nuclear localization signal |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000334944 | - | 12 | 14 | 15_19 | 527 | 639 | Motif | Nuclear localization signal |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377387 | - | 12 | 13 | 15_19 | 652 | 674 | Motif | Nuclear localization signal |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377390 | - | 12 | 13 | 15_19 | 527 | 640 | Motif | Nuclear localization signal |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377394 | - | 12 | 13 | 15_19 | 528 | 572 | Motif | Nuclear localization signal |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000433274 | - | 12 | 13 | 15_19 | 501 | 614 | Motif | Nuclear localization signal |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000227503 | - | 12 | 13 | 277_296 | 527 | 549 | Zinc finger | CCHC-type |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000334944 | - | 12 | 14 | 277_296 | 527 | 639 | Zinc finger | CCHC-type |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377387 | - | 12 | 13 | 277_296 | 652 | 674 | Zinc finger | CCHC-type |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377390 | - | 12 | 13 | 277_296 | 527 | 640 | Zinc finger | CCHC-type |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000377394 | - | 12 | 13 | 277_296 | 528 | 572 | Zinc finger | CCHC-type |
| Hgene | SF1 | chr11:64534372 | chr11:63326132 | ENST00000433274 | - | 12 | 13 | 277_296 | 501 | 614 | Zinc finger | CCHC-type |
| Tgene | >HRASLS2 | chr11:64534372 | chr11:63326132 | ENST00000255695 | - | 1 | 4 | 156_162 | 39 | 163 | Topological domain | Lumenal |
| Tgene | >HRASLS2 | chr11:64534372 | chr11:63326132 | ENST00000255695 | - | 1 | 4 | 133_155 | 39 | 163 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SF1 | chr11:64534372 | chr11:63326132 | ENST00000227503 | - | 12 | 13 | 324_637 | 527 | 549 | Compositional bias | Note=Pro-rich |
| Hgene | >SF1 | chr11:64534372 | chr11:63326132 | ENST00000334944 | - | 12 | 14 | 324_637 | 527 | 639 | Compositional bias | Note=Pro-rich |
| Hgene | >SF1 | chr11:64534372 | chr11:63326132 | ENST00000377390 | - | 12 | 13 | 324_637 | 527 | 640 | Compositional bias | Note=Pro-rich |
| Hgene | >SF1 | chr11:64534372 | chr11:63326132 | ENST00000377394 | - | 12 | 13 | 324_637 | 528 | 572 | Compositional bias | Note=Pro-rich |
| Hgene | >SF1 | chr11:64534372 | chr11:63326132 | ENST00000433274 | - | 12 | 13 | 324_637 | 501 | 614 | Compositional bias | Note=Pro-rich |
| Tgene | HRASLS2 | chr11:64534372 | chr11:63326132 | ENST00000255695 | - | 1 | 4 | 1_132 | 39 | 163 | Topological domain | Cytoplasmic |
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FusionGeneSequence for SF1_HRASLS2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SF1_ENST00000377387_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_776aa MATGANATPLGKLGPPGLPPLPGPKGGFEPGPPPAPGPGAGLLAPGPPPPPPVGSMGALTAAFPFAALPPPPPPPPPPPPQQPPPPPPPP SPGASYPPPQPPPPPPLYQRVSPPQPPPPQPPRKDQQPGPAGGGGDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQ LQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQD EYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPED QNDLRKMQLRELARLNGTLREDDNRILRPWQSSETRSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPV PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQH NPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQ QPPPPPPPSSSMASSTPLPWQQSEIAGAGAASVLSALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYS >In-frame_SF1_ENST00000377390_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_651aa MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSE GKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSET RSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQY LGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQSEIAGAGAASVLS ALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAG >In-frame_SF1_ENST00000227503_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_651aa MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSE GKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSET RSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQY LGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQSEIAGAGAASVLS ALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAG >In-frame_SF1_ENST00000334944_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_651aa MATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERAYIVQLQIEDLTRKLRTGDLGIPPNPEDRSPSPEPIYNSE GKRLNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGK GSVKEGKVGRKDGQMLPGEDEPLHALVTANTMENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGTLREDDNRILRPWQSSET RSITNTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMS TTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGHHGPPPMDQY LGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQSEIAGAGAASVLS ALTNKAIVKKELLSVVAGGDNYRVNNKHDDRYTPLPSNKIVKRAEELVGQELPYSLTSDNCEHFVNHLRYGVSRSDQVTGAVTTVGVAAG >In-frame_SF1_ENST00000422298_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_123aa VKLLELVRPVSCLPXPTKPXXRRNCCLWWLGETTTGSITSTMTDTHHCLPTKSSSGQRSWWGRSCLIRXPVTTASTSXTICAMASPAVTR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SF1_ENST00000377387_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_2328nt ATGGCGACCGGAGCGAACGCCACGCCGTTGGGTAAGCTGGGCCCCCCCGGGCTGCCCCCGCTCCCCGGGCCCAAAGGAGGCTTCGAGCCG GGCCCTCCGCCTGCACCCGGGCCTGGGGCGGGGCTGCTGGCTCCCGGGCCGCCGCCGCCCCCGCCCGTGGGCTCGATGGGGGCCCTGACC GCGGCCTTCCCCTTCGCGGCGCTGCCTCCGCCGCCTCCGCCGCCGCCCCCTCCGCCTCCCCAGCAGCCGCCGCCGCCTCCACCGCCACCG TCCCCCGGCGCCTCGTACCCGCCGCCGCAGCCGCCCCCTCCGCCGCCGCTCTACCAGCGCGTGTCGCCGCCGCAGCCGCCGCCACCCCAG CCGCCGCGTAAGGACCAGCAGCCGGGCCCGGCCGGCGGCGGAGGAGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAGAC ACAATGGAACAGAAGACAGTGATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGTGCAA CTGCAGATAGAAGACCTGACTCGTAAACTGCGCACAGGAGACCTGGGCATCCCCCCTAACCCTGAGGACAGGTCCCCTTCCCCTGAGCCC ATCTACAATAGCGAGGGGAAGCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCACAACCTCATCACAGAG ATGGTTGCACTCAATCCGGATTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGTCATGATTCCACAAGAT GAGTACCCAGAAATCAACTTTGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGAGTGCAATGCCAAGATT ATGATCCGGGGGAAAGGGTCTGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGATGAGCCACTTCATGCC CTGGTTACTGCCAATACAATGGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTATCGAGACTCCAGAGGAC CAGAATGATCTACGGAAGATGCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAGGATCTTAAGACCCTGG CAGAGCTCAGAGACCCGCAGCATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTCAGACTGTAAATTCCAA AGGCCTGGTGATCCTCAGTCAGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGAACTGGGTGAAGCACCTGTC CCAGCATCTGTGGGCTCCACCTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGCCAACAACCCACCTCCA CCGTCTCTCATGTCTACCACCCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCACGGCATGCATGGAGGT GGTCCTGGTGGGCCCGGAGGTGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGGTGGACATCCCATGCAGCAC AACCCCAATGGACCCCCACCCCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCCTGGGCACCATGGCCCTCCT CCAATGGATCAGTACCTGGGAAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGATGCCGCCACCACCTATG GGCATGATGCCGCCGCCGCCGCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATGGCAACAACAGCAGCAG CAGCCTCCGCCACCCCCTCCGCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAATTGCTGGAGCTGGTGCG GCCAGTGTCCTGTCTGCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGACAACTACAGGGTCAAT AACAAGCACGATGACAGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCAGGAGTTGCCTTATTCG CTGACCAGTGACAACTGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGGTGCAGTCACGACAGTA >In-frame_SF1_ENST00000377390_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_1953nt ATGGCGACCGGAGCGAACGCCACGCCGTTGGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAGACACAATGGAACAGAAG ACAGTGATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGTGCAACTGCAGATAGAAGAC CTGACTCGTAAACTGCGCACAGGAGACCTGGGCATCCCCCCTAACCCTGAGGACAGGTCCCCTTCCCCTGAGCCCATCTACAATAGCGAG GGGAAGCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCACAACCTCATCACAGAGATGGTTGCACTCAAT CCGGATTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGTCATGATTCCACAAGATGAGTACCCAGAAATC AACTTTGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGAGTGCAATGCCAAGATTATGATCCGGGGGAAA GGGTCTGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGATGAGCCACTTCATGCCCTGGTTACTGCCAAT ACAATGGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTATCGAGACTCCAGAGGACCAGAATGATCTACGG AAGATGCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAGGATCTTAAGACCCTGGCAGAGCTCAGAGACC CGCAGCATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTCAGACTGTAAATTCCAAAGGCCTGGTGATCCT CAGTCAGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGAACTGGGTGAAGCACCTGTCCCAGCATCTGTGGGC TCCACCTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGCCAACAACCCACCTCCACCGTCTCTCATGTCT ACCACCCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCACGGCATGCATGGAGGTGGTCCTGGTGGGCCC GGAGGTGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGGTGGACATCCCATGCAGCACAACCCCAATGGACCC CCACCCCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCCTGGGCACCATGGCCCTCCTCCAATGGATCAGTAC CTGGGAAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGATGCCGCCACCACCTATGGGCATGATGCCGCCG CCGCCGCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATGGCAACAACAGCAGCAGCAGCCTCCGCCACCC CCTCCGCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAATTGCTGGAGCTGGTGCGGCCAGTGTCCTGTCT GCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGACAACTACAGGGTCAATAACAAGCACGATGAC AGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCAGGAGTTGCCTTATTCGCTGACCAGTGACAAC TGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGGTGCAGTCACGACAGTAGGTGTGGCAGCAGGC >In-frame_SF1_ENST00000227503_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_1953nt ATGGCGACCGGAGCGAACGCCACGCCGTTGGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAGACACAATGGAACAGAAG ACAGTGATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGTGCAACTGCAGATAGAAGAC CTGACTCGTAAACTGCGCACAGGAGACCTGGGCATCCCCCCTAACCCTGAGGACAGGTCCCCTTCCCCTGAGCCCATCTACAATAGCGAG GGGAAGCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCACAACCTCATCACAGAGATGGTTGCACTCAAT CCGGATTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGTCATGATTCCACAAGATGAGTACCCAGAAATC AACTTTGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGAGTGCAATGCCAAGATTATGATCCGGGGGAAA GGGTCTGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGATGAGCCACTTCATGCCCTGGTTACTGCCAAT ACAATGGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTATCGAGACTCCAGAGGACCAGAATGATCTACGG AAGATGCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAGGATCTTAAGACCCTGGCAGAGCTCAGAGACC CGCAGCATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTCAGACTGTAAATTCCAAAGGCCTGGTGATCCT CAGTCAGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGAACTGGGTGAAGCACCTGTCCCAGCATCTGTGGGC TCCACCTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGCCAACAACCCACCTCCACCGTCTCTCATGTCT ACCACCCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCACGGCATGCATGGAGGTGGTCCTGGTGGGCCC GGAGGTGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGGTGGACATCCCATGCAGCACAACCCCAATGGACCC CCACCCCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCCTGGGCACCATGGCCCTCCTCCAATGGATCAGTAC CTGGGAAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGATGCCGCCACCACCTATGGGCATGATGCCGCCG CCGCCGCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATGGCAACAACAGCAGCAGCAGCCTCCGCCACCC CCTCCGCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAATTGCTGGAGCTGGTGCGGCCAGTGTCCTGTCT GCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGACAACTACAGGGTCAATAACAAGCACGATGAC AGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCAGGAGTTGCCTTATTCGCTGACCAGTGACAAC TGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGGTGCAGTCACGACAGTAGGTGTGGCAGCAGGC >In-frame_SF1_ENST00000334944_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_1953nt ATGGCGACCGGAGCGAACGCCACGCCGTTGGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAGACACAATGGAACAGAAG ACAGTGATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGTGCAACTGCAGATAGAAGAC CTGACTCGTAAACTGCGCACAGGAGACCTGGGCATCCCCCCTAACCCTGAGGACAGGTCCCCTTCCCCTGAGCCCATCTACAATAGCGAG GGGAAGCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCACAACCTCATCACAGAGATGGTTGCACTCAAT CCGGATTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGTCATGATTCCACAAGATGAGTACCCAGAAATC AACTTTGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGAGTGCAATGCCAAGATTATGATCCGGGGGAAA GGGTCTGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGATGAGCCACTTCATGCCCTGGTTACTGCCAAT ACAATGGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTATCGAGACTCCAGAGGACCAGAATGATCTACGG AAGATGCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAGGATCTTAAGACCCTGGCAGAGCTCAGAGACC CGCAGCATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTCAGACTGTAAATTCCAAAGGCCTGGTGATCCT CAGTCAGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGAACTGGGTGAAGCACCTGTCCCAGCATCTGTGGGC TCCACCTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGCCAACAACCCACCTCCACCGTCTCTCATGTCT ACCACCCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCACGGCATGCATGGAGGTGGTCCTGGTGGGCCC GGAGGTGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGGTGGACATCCCATGCAGCACAACCCCAATGGACCC CCACCCCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCCTGGGCACCATGGCCCTCCTCCAATGGATCAGTAC CTGGGAAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGATGCCGCCACCACCTATGGGCATGATGCCGCCG CCGCCGCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATGGCAACAACAGCAGCAGCAGCCTCCGCCACCC CCTCCGCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAATTGCTGGAGCTGGTGCGGCCAGTGTCCTGTCT GCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGACAACTACAGGGTCAATAACAAGCACGATGAC AGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCAGGAGTTGCCTTATTCGCTGACCAGTGACAAC TGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGGTGCAGTCACGACAGTAGGTGTGGCAGCAGGC >In-frame_SF1_ENST00000422298_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_371nt GTGAAATTGCTGGAGCTGGTGCGGCCAGTGTCCTGTCTGCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTG GGGGAGACAACTACAGGGTCAATAACAAGCACGATGACAGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGG TGGGGCAGGAGTTGCCTTATTCGCTGACCAGTGACAACTGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGG TCACTGGTGCAGTCACGACAGTAGGTGTGGCAGCAGGCCTGCTGGCTGCCGCAAGCCTTGTGGGGATCCTGCTGGCCAGAAGCAAGCGGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SF1_ENST00000377387_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_2599nt CCTCCCCCCGGGAGGCTTGCGAAGGAGAAGCCGCCGCAGAGGAAAAGCAGGTGCCGGTGCCTGTCCCCGGGGGCGCCATGGCGACCGGAG CGAACGCCACGCCGTTGGGTAAGCTGGGCCCCCCCGGGCTGCCCCCGCTCCCCGGGCCCAAAGGAGGCTTCGAGCCGGGCCCTCCGCCTG CACCCGGGCCTGGGGCGGGGCTGCTGGCTCCCGGGCCGCCGCCGCCCCCGCCCGTGGGCTCGATGGGGGCCCTGACCGCGGCCTTCCCCT TCGCGGCGCTGCCTCCGCCGCCTCCGCCGCCGCCCCCTCCGCCTCCCCAGCAGCCGCCGCCGCCTCCACCGCCACCGTCCCCCGGCGCCT CGTACCCGCCGCCGCAGCCGCCCCCTCCGCCGCCGCTCTACCAGCGCGTGTCGCCGCCGCAGCCGCCGCCACCCCAGCCGCCGCGTAAGG ACCAGCAGCCGGGCCCGGCCGGCGGCGGAGGAGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAGACACAATGGAACAGA AGACAGTGATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGTGCAACTGCAGATAGAAG ACCTGACTCGTAAACTGCGCACAGGAGACCTGGGCATCCCCCCTAACCCTGAGGACAGGTCCCCTTCCCCTGAGCCCATCTACAATAGCG AGGGGAAGCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCACAACCTCATCACAGAGATGGTTGCACTCA ATCCGGATTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGTCATGATTCCACAAGATGAGTACCCAGAAA TCAACTTTGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGAGTGCAATGCCAAGATTATGATCCGGGGGA AAGGGTCTGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGATGAGCCACTTCATGCCCTGGTTACTGCCA ATACAATGGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTATCGAGACTCCAGAGGACCAGAATGATCTAC GGAAGATGCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAGGATCTTAAGACCCTGGCAGAGCTCAGAGA CCCGCAGCATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTCAGACTGTAAATTCCAAAGGCCTGGTGATC CTCAGTCAGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGAACTGGGTGAAGCACCTGTCCCAGCATCTGTGG GCTCCACCTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGCCAACAACCCACCTCCACCGTCTCTCATGT CTACCACCCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCACGGCATGCATGGAGGTGGTCCTGGTGGGC CCGGAGGTGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGGTGGACATCCCATGCAGCACAACCCCAATGGAC CCCCACCCCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCCTGGGCACCATGGCCCTCCTCCAATGGATCAGT ACCTGGGAAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGATGCCGCCACCACCTATGGGCATGATGCCGC CGCCGCCGCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATGGCAACAACAGCAGCAGCAGCCTCCGCCAC CCCCTCCGCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAATTGCTGGAGCTGGTGCGGCCAGTGTCCTGT CTGCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGACAACTACAGGGTCAATAACAAGCACGATG ACAGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCAGGAGTTGCCTTATTCGCTGACCAGTGACA ACTGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGGTGCAGTCACGACAGTAGGTGTGGCAGCAG GCCTGCTGGCTGCCGCAAGCCTTGTGGGGATCCTGCTGGCCAGAAGCAAGCGGGAAAGGCAATAAATCCAAGAAATTGTCCCAACAACCA CCAATTCTTACGGAGGAATATTATTTAGCCAGCAGGAGTGGAGTTTGGTTTACTGATTTTACTGTTTTGTGTTCATGAATCTTTATTTTA >In-frame_SF1_ENST00000377390_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_2485nt ACCGAACTCCGCCGCCATTTCCTCGCTTGGCCTAACGGTTCGGCCAATCCCAGCGCGCATCAAGAAGGACTGAGGCTCCGCCAATCGGAG GCCGCCGATTTCGACCCTTCGCCTCGGCCCGGCCCAATCCAGGCCCCGGCCCCGCCGCCCCCGGCCCGCCCCCGCGGTGCCCTCTCTCCT CCCTCTTTGTGCGTCTCGCGCCGCCGCCGCCCGCCGCGTGAGAGGACGGGCTCCGCGCGCTCCGGCAGCGCATTCGGGTCCCCTCCCCCC GGGAGGCTTGCGAAGGAGAAGCCGCCGCAGAGGAAAAGCAGGTGCCGGTGCCTGTCCCCGGGGGCGCCATGGCGACCGGAGCGAACGCCA CGCCGTTGGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAGACACAATGGAACAGAAGACAGTGATTCCAGGAATGCCTA CAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGTGCAACTGCAGATAGAAGACCTGACTCGTAAACTGCGCACAG GAGACCTGGGCATCCCCCCTAACCCTGAGGACAGGTCCCCTTCCCCTGAGCCCATCTACAATAGCGAGGGGAAGCGGCTTAACACCCGAG AGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCACAACCTCATCACAGAGATGGTTGCACTCAATCCGGATTTCAAGCCACCTGCAG ATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGTCATGATTCCACAAGATGAGTACCCAGAAATCAACTTTGTGGGGCTGCTCATCG GGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGAGTGCAATGCCAAGATTATGATCCGGGGGAAAGGGTCTGTGAAAGAAGGGAAGG TTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGATGAGCCACTTCATGCCCTGGTTACTGCCAATACAATGGAGAACGTCAAAAAGG CAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTATCGAGACTCCAGAGGACCAGAATGATCTACGGAAGATGCAGCTTCGGGAGTTGG CTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAGGATCTTAAGACCCTGGCAGAGCTCAGAGACCCGCAGCATTACCAACACCACAG TGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTCAGACTGTAAATTCCAAAGGCCTGGTGATCCTCAGTCAGCTCAGGATAAAGCAC GGATGGATAAAGAATATTTGTCCCTCATGGCTGAACTGGGTGAAGCACCTGTCCCAGCATCTGTGGGCTCCACCTCTGGGCCTGCCACCA CACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGCCAACAACCCACCTCCACCGTCTCTCATGTCTACCACCCAGAGCCGCCCACCCT GGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCACGGCATGCATGGAGGTGGTCCTGGTGGGCCCGGAGGTGGCCCCCACAGCTTCC CACACCCATTACCCAGCCTGACAGGTGGGCATGGTGGACATCCCATGCAGCACAACCCCAATGGACCCCCACCCCCTTGGATGCAGCCAC CACCACCACCGATGAACCAGGGCCCCCACCCTCCTGGGCACCATGGCCCTCCTCCAATGGATCAGTACCTGGGAAGTACGCCTGTGGGCT CTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGATGCCGCCACCACCTATGGGCATGATGCCGCCGCCGCCGCCGCCTCCCAGTGGGC AGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATGGCAACAACAGCAGCAGCAGCCTCCGCCACCCCCTCCGCCCAGCAGCAGTATGG CTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAATTGCTGGAGCTGGTGCGGCCAGTGTCCTGTCTGCCCTGACCAACAAAGCCATAG TGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGACAACTACAGGGTCAATAACAAGCACGATGACAGATACACACCACTGCCTTCCA ACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCAGGAGTTGCCTTATTCGCTGACCAGTGACAACTGCGAGCACTTCGTGAACCATC TGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGGTGCAGTCACGACAGTAGGTGTGGCAGCAGGCCTGCTGGCTGCCGCAAGCCTTG TGGGGATCCTGCTGGCCAGAAGCAAGCGGGAAAGGCAATAAATCCAAGAAATTGTCCCAACAACCACCAATTCTTACGGAGGAATATTAT TTAGCCAGCAGGAGTGGAGTTTGGTTTACTGATTTTACTGTTTTGTGTTCATGAATCTTTATTTTAATGGAGTTAAAAGCACAGGAAAAT >In-frame_SF1_ENST00000227503_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_2502nt GCGACACCTCCCAGCCCACCGAACTCCGCCGCCATTTCCTCGCTTGGCCTAACGGTTCGGCCAATCCCAGCGCGCATCAAGAAGGACTGA GGCTCCGCCAATCGGAGGCCGCCGATTTCGACCCTTCGCCTCGGCCCGGCCCAATCCAGGCCCCGGCCCCGCCGCCCCCGGCCCGCCCCC GCGGTGCCCTCTCTCCTCCCTCTTTGTGCGTCTCGCGCCGCCGCCGCCCGCCGCGTGAGAGGACGGGCTCCGCGCGCTCCGGCAGCGCAT TCGGGTCCCCTCCCCCCGGGAGGCTTGCGAAGGAGAAGCCGCCGCAGAGGAAAAGCAGGTGCCGGTGCCTGTCCCCGGGGGCGCCATGGC GACCGGAGCGAACGCCACGCCGTTGGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAGACACAATGGAACAGAAGACAGT GATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGTGCAACTGCAGATAGAAGACCTGAC TCGTAAACTGCGCACAGGAGACCTGGGCATCCCCCCTAACCCTGAGGACAGGTCCCCTTCCCCTGAGCCCATCTACAATAGCGAGGGGAA GCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCACAACCTCATCACAGAGATGGTTGCACTCAATCCGGA TTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGTCATGATTCCACAAGATGAGTACCCAGAAATCAACTT TGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGAGTGCAATGCCAAGATTATGATCCGGGGGAAAGGGTC TGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGATGAGCCACTTCATGCCCTGGTTACTGCCAATACAAT GGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTATCGAGACTCCAGAGGACCAGAATGATCTACGGAAGAT GCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAGGATCTTAAGACCCTGGCAGAGCTCAGAGACCCGCAG CATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTCAGACTGTAAATTCCAAAGGCCTGGTGATCCTCAGTC AGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGAACTGGGTGAAGCACCTGTCCCAGCATCTGTGGGCTCCAC CTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGCCAACAACCCACCTCCACCGTCTCTCATGTCTACCAC CCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCACGGCATGCATGGAGGTGGTCCTGGTGGGCCCGGAGG TGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGGTGGACATCCCATGCAGCACAACCCCAATGGACCCCCACC CCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCCTGGGCACCATGGCCCTCCTCCAATGGATCAGTACCTGGG AAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGATGCCGCCACCACCTATGGGCATGATGCCGCCGCCGCC GCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATGGCAACAACAGCAGCAGCAGCCTCCGCCACCCCCTCC GCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAATTGCTGGAGCTGGTGCGGCCAGTGTCCTGTCTGCCCT GACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGACAACTACAGGGTCAATAACAAGCACGATGACAGATA CACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCAGGAGTTGCCTTATTCGCTGACCAGTGACAACTGCGA GCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGGTGCAGTCACGACAGTAGGTGTGGCAGCAGGCCTGCT GGCTGCCGCAAGCCTTGTGGGGATCCTGCTGGCCAGAAGCAAGCGGGAAAGGCAATAAATCCAAGAAATTGTCCCAACAACCACCAATTC TTACGGAGGAATATTATTTAGCCAGCAGGAGTGGAGTTTGGTTTACTGATTTTACTGTTTTGTGTTCATGAATCTTTATTTTAATGGAGT >In-frame_SF1_ENST00000334944_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_2541nt CGGAGCTCAGTTCACGCAGTAACAAATGAAGTGCGCGCTGCGACACCTCCCAGCCCACCGAACTCCGCCGCCATTTCCTCGCTTGGCCTA ACGGTTCGGCCAATCCCAGCGCGCATCAAGAAGGACTGAGGCTCCGCCAATCGGAGGCCGCCGATTTCGACCCTTCGCCTCGGCCCGGCC CAATCCAGGCCCCGGCCCCGCCGCCCCCGGCCCGCCCCCGCGGTGCCCTCTCTCCTCCCTCTTTGTGCGTCTCGCGCCGCCGCCGCCCGC CGCGTGAGAGGACGGGCTCCGCGCGCTCCGGCAGCGCATTCGGGTCCCCTCCCCCCGGGAGGCTTGCGAAGGAGAAGCCGCCGCAGAGGA AAAGCAGGTGCCGGTGCCTGTCCCCGGGGGCGCCATGGCGACCGGAGCGAACGCCACGCCGTTGGACTTCCCAAGTAAGAAGCGGAAGAG GAGCCGCTGGAACCAAGACACAATGGAACAGAAGACAGTGATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGA AAGAGCTTATATAGTGCAACTGCAGATAGAAGACCTGACTCGTAAACTGCGCACAGGAGACCTGGGCATCCCCCCTAACCCTGAGGACAG GTCCCCTTCCCCTGAGCCCATCTACAATAGCGAGGGGAAGCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCG GCACAACCTCATCACAGAGATGGTTGCACTCAATCCGGATTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAA AGTCATGATTCCACAAGATGAGTACCCAGAAATCAACTTTGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAA GGAGTGCAATGCCAAGATTATGATCCGGGGGAAAGGGTCTGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGA AGATGAGCCACTTCATGCCCTGGTTACTGCCAATACAATGGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGG TATCGAGACTCCAGAGGACCAGAATGATCTACGGAAGATGCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAA CAGGATCTTAAGACCCTGGCAGAGCTCAGAGACCCGCAGCATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGC TTCAGACTGTAAATTCCAAAGGCCTGGTGATCCTCAGTCAGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGA ACTGGGTGAAGCACCTGTCCCAGCATCTGTGGGCTCCACCTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCC CGCCAACAACCCACCTCCACCGTCTCTCATGTCTACCACCCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTA CCACGGCATGCATGGAGGTGGTCCTGGTGGGCCCGGAGGTGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGG TGGACATCCCATGCAGCACAACCCCAATGGACCCCCACCCCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCC TGGGCACCATGGCCCTCCTCCAATGGATCAGTACCTGGGAAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTAT GATGCCGCCACCACCTATGGGCATGATGCCGCCGCCGCCGCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCC ATGGCAACAACAGCAGCAGCAGCCTCCGCCACCCCCTCCGCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGA AATTGCTGGAGCTGGTGCGGCCAGTGTCCTGTCTGCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGG AGACAACTACAGGGTCAATAACAAGCACGATGACAGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGG GCAGGAGTTGCCTTATTCGCTGACCAGTGACAACTGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCAC TGGTGCAGTCACGACAGTAGGTGTGGCAGCAGGCCTGCTGGCTGCCGCAAGCCTTGTGGGGATCCTGCTGGCCAGAAGCAAGCGGGAAAG GCAATAAATCCAAGAAATTGTCCCAACAACCACCAATTCTTACGGAGGAATATTATTTAGCCAGCAGGAGTGGAGTTTGGTTTACTGATT TTACTGTTTTGTGTTCATGAATCTTTATTTTAATGGAGTTAAAAGCACAGGAAAATGTATTTGGAAATGCAGCTTAGTATGAATTCTATT >In-frame_SF1_ENST00000422298_chr11_64534372_-_HRASLS2_ENST00000255695_chr11_63326132_-_2448nt AGTAACAAATGAAGTGCGCGCTGCGACACCTCCCAGCCCACCGAACTCCGCCGCCATTTCCTCGCTTGGCCTAACGGTTCGGCCAATCCC AGCGCGCATCAAGAAGGACTGAGGCTCCGCCAATCGGAGGCCGCCGATTTCGACCCTTCGCCTCGGCCCGGCCCAATCCAGGCCCCGGCC CCGCCGCCCCCGGCCCGCCCCCGCGGTGCCCTCTCTCCTCCCTCTTTGTGCGTCTCGCGCCGCCGCCGCCCGCCGCGTGAGAGGACGGGC TCCGCGCGCTCCGGCAGCGCATTCGGGTCCCCTCCCCCCGGGAGGCTTGCGAAGGAGAAGCCGCCGCAGAGGAAAAGCAGGTGCCGGTGC CTGTCCCCGGGGGCGCCATGGCGACCGGAGCGAACGCCACGCCGTTGGACTTCCCAAGTAAGAAGCGGAAGAGGAGCCGCTGGAACCAAG ACACAATGGAACAGAAGACAGTGATTCCAGGAATGCCTACAGTTATTCCCCCTGGACTTACTCGAGAACAAGAAAGAGCTTATATAGGTC CCCTTCCCCTGAGCCCATCTACAATAGCGAGGGGAAGCGGCTTAACACCCGAGAGTTCCGCACCCGCAAAAAGCTGGAAGAGGAGCGGCA CAACCTCATCACAGAGATGGTTGCACTCAATCCGGATTTCAAGCCACCTGCAGATTACAAACCTCCAGCAACACGTGTGAGTGATAAAGT CATGATTCCACAAGATGAGTACCCAGAAATCAACTTTGTGGGGCTGCTCATCGGGCCCAGAGGGAACACCCTGAAGAACATAGAGAAGGA GTGCAATGCCAAGATTATGATCCGGGGGAAAGGGTCTGTGAAAGAAGGGAAGGTTGGGCGCAAAGATGGCCAGATGTTGCCAGGAGAAGA TGAGCCACTTCATGCCCTGGTTACTGCCAATACAATGGAGAACGTCAAAAAGGCAGTGGAACAGATAAGAAACATCCTGAAGCAGGGTAT CGAGACTCCAGAGGACCAGAATGATCTACGGAAGATGCAGCTTCGGGAGTTGGCTCGCTTAAATGGGACCCTTCGGGAAGACGATAACAG GATCTTAAGACCCTGGCAGAGCTCAGAGACCCGCAGCATTACCAACACCACAGTGTGTACCAAGTGTGGAGGGGCTGGCCACATTGCTTC AGACTGTAAATTCCAAAGGCCTGGTGATCCTCAGTCAGCTCAGGATAAAGCACGGATGGATAAAGAATATTTGTCCCTCATGGCTGAACT GGGTGAAGCACCTGTCCCAGCATCTGTGGGCTCCACCTCTGGGCCTGCCACCACACCCCTGGCCAGCGCACCTCGTCCTGCTGCTCCCGC CAACAACCCACCTCCACCGTCTCTCATGTCTACCACCCAGAGCCGCCCACCCTGGATGAATTCTGGCCCTTCAGAGAGTCGGCCCTACCA CGGCATGCATGGAGGTGGTCCTGGTGGGCCCGGAGGTGGCCCCCACAGCTTCCCACACCCATTACCCAGCCTGACAGGTGGGCATGGTGG ACATCCCATGCAGCACAACCCCAATGGACCCCCACCCCCTTGGATGCAGCCACCACCACCACCGATGAACCAGGGCCCCCACCCTCCTGG GCACCATGGCCCTCCTCCAATGGATCAGTACCTGGGAAGTACGCCTGTGGGCTCTGGGGTCTATCGCCTGCATCAAGGAAAAGGTATGAT GCCGCCACCACCTATGGGCATGATGCCGCCGCCGCCGCCGCCTCCCAGTGGGCAGCCCCCACCCCCTCCCTCTGGTCCTCTTCCCCCATG GCAACAACAGCAGCAGCAGCCTCCGCCACCCCCTCCGCCCAGCAGCAGTATGGCTTCCAGTACCCCCTTGCCATGGCAGCAAAGTGAAAT TGCTGGAGCTGGTGCGGCCAGTGTCCTGTCTGCCCTGACCAACAAAGCCATAGTGAAGAAGGAACTGCTGTCTGTGGTGGCTGGGGGAGA CAACTACAGGGTCAATAACAAGCACGATGACAGATACACACCACTGCCTTCCAACAAAATCGTCAAGCGGGCAGAGGAGTTGGTGGGGCA GGAGTTGCCTTATTCGCTGACCAGTGACAACTGCGAGCACTTCGTGAACCATCTGCGCTATGGCGTCTCCCGCAGTGACCAGGTCACTGG TGCAGTCACGACAGTAGGTGTGGCAGCAGGCCTGCTGGCTGCCGCAAGCCTTGTGGGGATCCTGCTGGCCAGAAGCAAGCGGGAAAGGCA ATAAATCCAAGAAATTGTCCCAACAACCACCAATTCTTACGGAGGAATATTATTTAGCCAGCAGGAGTGGAGTTTGGTTTACTGATTTTA CTGTTTTGTGTTCATGAATCTTTATTTTAATGGAGTTAAAAGCACAGGAAAATGTATTTGGAAATGCAGCTTAGTATGAATTCTATTAAA |
Top |
FusionGenePPI for SF1_HRASLS2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SF1 | PLSCR1, TRIM23, DDX17, WWP2, RBPMS, U2AF2, EWSR1, FUS, TAF15, TCERG1, ZNF461, NCOR2, PML, PPARGC1A, NFKB1, HDAC5, HDAC4, SF3A2, CUL3, CIRBP, EFTUD2, VDAC1, MPLKIP, ZC3H11A, TMED4, TOMM40, SRPRB, VDAC3, STIM1, UBE2L3, VAMP2, TAGLN, ZFR, SORCS3, SBDS, SEPT11, SIN3A, STOM, NNT, SRP9, ATXN1, FN1, VCAM1, SF3A1, SF3B4, RBM17, RBM10, SF1, ILF3, BCAS2, WDR83, RBM7, HNRNPK, HNRNPUL1, RBM4, WDR77, HNRNPF, HNRNPH1, HNRNPH2, IL7R, METTL22, ITGA4, LMNA, ITCH, PRPF40A, WBP4, APBB1, GAS7, RANBP3, EIF4B, FAF1, FARSB, GART, GFPT1, HIRIP3, HIST1H4A, HSPH1, NARS, OSBP, PLOD2, RPL24, SAMHD1, SUPT5H, TROVE2, XPO7, XRCC5, CIAO1, PSMA3, MKRN3, FAM168A, TRIM69, KRTAP26-1, CUL7, OBSL1, CCDC8, SUZ12, EED, PRMT2, ACTL6A, ZFP41, CAB39, CCDC25, ALDOC, CNN2, HADH, HNRNPL, HSDL2, IREB2, PGK1, PLAA, PPID, TKT, UBE2N, NTRK1, NCOA1, CDC42, CSNK2A2, LLGL2, MAPK8, EMC2, RNF41, PARD6B, KLC3, NAGK, P4HA3, BCHE, CAPN13, HSPBP1, HAO2, SFPQ, FOXA1, TES | HRASLS2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SF1_HRASLS2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | SF1 | Q15637 | DB11638 | Artenimol | Splicing factor 1 | small molecule | approved|investigational |
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RelatedDiseases for SF1_HRASLS2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SF1 | C0025202 | melanoma | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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