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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 33353

FusionGeneSummary for SETBP1_ARNTL

check button Fusion gene summary
Fusion gene informationFusion gene name: SETBP1_ARNTL
Fusion gene ID: 33353
HgeneTgene
Gene symbol

SETBP1

ARNTL

Gene ID

26040

406

Gene nameSET binding protein 1aryl hydrocarbon receptor nuclear translocator like
SynonymsMRD29|SEBBMAL1|BMAL1c|JAP3|MOP3|PASD3|TIC|bHLHe5
Cytomap

18q12.3

11p15.3

Type of geneprotein-codingprotein-coding
DescriptionSET-binding proteinaryl hydrocarbon receptor nuclear translocator-like protein 1ARNT-like protein 1, brain and musclePAS domain containing 3PAS domain-containing protein 3bHLH-PAS protein JAP3basic helix-loop-helix family member e5basic-helix-loop-helix-PAS orphan MOP
Modification date2018051920180519
UniProtAcc

Q9Y6X0

O00327

Ensembl transtripts involved in fusion geneENST00000426838, ENST00000282030, 
ENST00000396441, ENST00000389707, 
ENST00000401424, ENST00000389708, 
ENST00000361003, ENST00000403290, 
ENST00000403510, ENST00000403482, 
ENST00000497429, 
Fusion gene scores* DoF score4 X 3 X 3=365 X 6 X 5=150
# samples 47
** MAII scorelog2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(7/150*10)=-1.09953567355091
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SETBP1 [Title/Abstract] AND ARNTL [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneARNTL

GO:0032922

circadian regulation of gene expression

24005054

TgeneARNTL

GO:0045893

positive regulation of transcription, DNA-templated

11441146|12738229|23785138

TgeneARNTL

GO:0045944

positive regulation of transcription by RNA polymerase II

20093779

TgeneARNTL

GO:0051775

response to redox state

11441146


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVUCECTCGA-AJ-A3QS-01ASETBP1chr18

42449248

+ARNTLchr11

13407236

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000426838ENST00000396441SETBP1chr18

42449248

+ARNTLchr11

13407236

+
In-frameENST00000426838ENST00000389707SETBP1chr18

42449248

+ARNTLchr11

13407236

+
In-frameENST00000426838ENST00000401424SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000389708SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000361003SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000403290SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000403510SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000426838ENST00000403482SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-intronENST00000426838ENST00000497429SETBP1chr18

42449248

+ARNTLchr11

13407236

+
In-frameENST00000282030ENST00000396441SETBP1chr18

42449248

+ARNTLchr11

13407236

+
In-frameENST00000282030ENST00000389707SETBP1chr18

42449248

+ARNTLchr11

13407236

+
In-frameENST00000282030ENST00000401424SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000389708SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000361003SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000403290SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000403510SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-3UTRENST00000282030ENST00000403482SETBP1chr18

42449248

+ARNTLchr11

13407236

+
5CDS-intronENST00000282030ENST00000497429SETBP1chr18

42449248

+ARNTLchr11

13407236

+

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FusionProtFeatures for SETBP1_ARNTL


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SETBP1

Q9Y6X0

ARNTL

O00327


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030+361016_10281801597DNA bindingNote=A.T hook 2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030+361451_14631801597DNA bindingNote=A.T hook 3
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030+36584_5961801597DNA bindingNote=A.T hook 1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838+341016_1028180243DNA bindingNote=A.T hook 2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838+341451_1463180243DNA bindingNote=A.T hook 3
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838+34584_596180243DNA bindingNote=A.T hook 1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030+361520_15431801597RegionNote=3 X 8 AA tandem repeats of P-P-L-P-P-P-P-P
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838+341520_1543180243RegionNote=3 X 8 AA tandem repeats of P-P-L-P-P-P-P-P
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030+361520_15271801597RepeatNote=1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030+361528_15351801597RepeatNote=2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000282030+361536_15431801597RepeatNote=3
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838+341520_1527180243RepeatNote=1
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838+341528_1535180243RepeatNote=2
HgeneSETBP1chr18:42449248chr11:13407236ENST00000426838+341536_1543180243RepeatNote=3
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+1518143_215421509DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+1518326_396421509DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+1518401_444421509DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+151872_125421509DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+1720143_215538626DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+1720326_396538626DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+1720401_444538626DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+172072_125538626DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+1619143_215538626DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+1619326_396538626DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+1619401_444538626DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+161972_125538626DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+1720143_215496584DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+1720326_396496584DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+1720401_444496584DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+172072_125496584DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+1720143_215539627DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+1720326_396539627DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+1720401_444539627DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+172072_125539627DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+1114143_215537625DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+1114326_396537625DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+1114401_444537625DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+111472_125537625DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+1720143_215495583DomainPAS 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+1720326_396495583DomainPAS 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+1720401_444495583DomainNote=PAC
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+172072_125495583DomainbHLH
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+1518142_152421509MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+1518361_369421509MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+151836_41421509MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+1720142_152538626MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+1720361_369538626MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+172036_41538626MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+1619142_152538626MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+1619361_369538626MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+161936_41538626MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+1720142_152496584MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+1720361_369496584MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+172036_41496584MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+1720142_152539627MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+1720361_369539627MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+172036_41539627MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+1114142_152537625MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+1114361_369537625MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+111436_41537625MotifNuclear localization signal
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+1720142_152495583MotifNuclear export signal 1
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+1720361_369495583MotifNuclear export signal 2
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+172036_41495583MotifNuclear localization signal


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FusionGeneSequence for SETBP1_ARNTL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000396441_chr11_13407236_+_268aa
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000389707_chr11_13407236_+_268aa
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000401424_chr11_13407236_+_268aa
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000396441_chr11_13407236_+_268aa
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000389707_chr11_13407236_+_268aa
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000401424_chr11_13407236_+_268aa
MESRETLSSSRQRGGESDFLPVSSAKPPAAPGCAGEPLLSTPGPGKGIPVGGERMEPEEEDELGSGRDVDSNSNADSEKWVAGDGLEEQE
FSIKEANFTEGSLKLKIQTTKRAKKPPKNLENYICPPEIKITIKQSGDQKVSRAGKNSKATKEEERSHSKKKLLTASDLAASDLKGFQPQ


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000396441_chr11_13407236_+_804nt
ATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCT
CCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAG
GATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAA
TTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTG
GAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCC
ACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAG
ATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGAACCCAGGTTATCCATATTCTGATAGT
TCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCA

>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000389707_chr11_13407236_+_804nt
ATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCT
CCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAG
GATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAA
TTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTG
GAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCC
ACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAG
ATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGAACCCAGGTTATCCATATTCTGATAGT
TCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCA

>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000401424_chr11_13407236_+_804nt
ATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCT
CCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAG
GATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAA
TTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTG
GAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCC
ACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAG
ATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGAACCCAGGTTATCCATATTCTGATAGT
TCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCA

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000396441_chr11_13407236_+_804nt
ATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCT
CCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAG
GATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAA
TTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTG
GAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCC
ACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAG
ATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGAACCCAGGTTATCCATATTCTGATAGT
TCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCA

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000389707_chr11_13407236_+_804nt
ATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCT
CCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAG
GATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAA
TTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTG
GAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCC
ACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAG
ATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGAACCCAGGTTATCCATATTCTGATAGT
TCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCA

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000401424_chr11_13407236_+_804nt
ATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCT
CCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAG
GATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAA
TTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTG
GAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCC
ACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAG
ATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGAACCCAGGTTATCCATATTCTGATAGT
TCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCA


* Fusion transcript sequences (Full-length transcript).
>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000396441_chr11_13407236_+_1704nt
AAGCGCGGGGCCGGCCGGGGCGCCCGCCGCTCGCCGCCGCCTCCGCGCGCCCGGGGGCCCCGGCGCCCCCCGAGCTAGGGCGGCCAGCTC
GCGGCTCGCCGTTTGACAGATGCTCATCGCCATGGAGTTGCCGCAGCAGCACCTTTGGGGGCTCGGGCGAGCGACGGGAGCCGGGATCTG
AGCGAGCGCCGGGGCCAGCGGAGCCGGAGCCGCCGGGACATGGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTG
GGAATCTGACCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCC
CCTCCTGAGAACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACT
TCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCC
CGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGA
AATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGA
CCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACC
AGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACC
TTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGG
CTCAGGAGAACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACC
AAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTG
ACTTTAGTGACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTAC
AGTCTGTGAAGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCT
TACTATATGTAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCAT
TAATTGTATATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCAT
TTCAGATGTATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCT

>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000389707_chr11_13407236_+_1709nt
AAGCGCGGGGCCGGCCGGGGCGCCCGCCGCTCGCCGCCGCCTCCGCGCGCCCGGGGGCCCCGGCGCCCCCCGAGCTAGGGCGGCCAGCTC
GCGGCTCGCCGTTTGACAGATGCTCATCGCCATGGAGTTGCCGCAGCAGCACCTTTGGGGGCTCGGGCGAGCGACGGGAGCCGGGATCTG
AGCGAGCGCCGGGGCCAGCGGAGCCGGAGCCGCCGGGACATGGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTG
GGAATCTGACCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCC
CCTCCTGAGAACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACT
TCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCC
CGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGA
AATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGA
CCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACC
AGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACC
TTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGG
CTCAGGAGAACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACC
AAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTG
ACTTTAGTGACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTAC
AGTCTGTGAAGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCT
TACTATATGTAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCAT
TAATTGTATATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCAT
TTCAGATGTATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCT

>In-frame_SETBP1_ENST00000426838_chr18_42449248_+_ARNTL_ENST00000401424_chr11_13407236_+_1709nt
AAGCGCGGGGCCGGCCGGGGCGCCCGCCGCTCGCCGCCGCCTCCGCGCGCCCGGGGGCCCCGGCGCCCCCCGAGCTAGGGCGGCCAGCTC
GCGGCTCGCCGTTTGACAGATGCTCATCGCCATGGAGTTGCCGCAGCAGCACCTTTGGGGGCTCGGGCGAGCGACGGGAGCCGGGATCTG
AGCGAGCGCCGGGGCCAGCGGAGCCGGAGCCGCCGGGACATGGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTG
GGAATCTGACCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCC
CCTCCTGAGAACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACT
TCCTGCCGGTCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCC
CGGTGGGCGGAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGA
AATGGGTGGCAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGA
CCACAAAGCGGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACC
AGAAGGTGTCCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACC
TTGCAGCCAGTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGG
CTCAGGAGAACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACC
AAGGATCAAGTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTG
ACTTTAGTGACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTAC
AGTCTGTGAAGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCT
TACTATATGTAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCAT
TAATTGTATATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCAT
TTCAGATGTATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCT

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000396441_chr11_13407236_+_1605nt
GGTTAAGTGGAGCTAGAGAGCTACATTGTAACCTAGTTGGATTTTTTTGGGGGGGGAATGTATCAGAATCTAACGTGTCGTTAATAGAAA
GAAGAACAGGCAAGAAGTGGTCCAGCCGGCGAAGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTGGGAATCTGA
CCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCCCCTCCTGAG
AACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGG
TCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCG
GAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGG
CAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGC
GGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGT
CCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCA
GTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGA
ACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAA
GTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTGACTTTAGTG
ACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTACAGTCTGTGA
AGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCTTACTATATG
TAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCATTAATTGTAT
ATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCATTTCAGATGT
ATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCTTGTAAGAAT

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000389707_chr11_13407236_+_1610nt
GGTTAAGTGGAGCTAGAGAGCTACATTGTAACCTAGTTGGATTTTTTTGGGGGGGGAATGTATCAGAATCTAACGTGTCGTTAATAGAAA
GAAGAACAGGCAAGAAGTGGTCCAGCCGGCGAAGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTGGGAATCTGA
CCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCCCCTCCTGAG
AACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGG
TCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCG
GAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGG
CAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGC
GGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGT
CCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCA
GTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGA
ACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAA
GTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTGACTTTAGTG
ACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTACAGTCTGTGA
AGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCTTACTATATG
TAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCATTAATTGTAT
ATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCATTTCAGATGT
ATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCTTGTAAGAAT

>In-frame_SETBP1_ENST00000282030_chr18_42449248_+_ARNTL_ENST00000401424_chr11_13407236_+_1610nt
GGTTAAGTGGAGCTAGAGAGCTACATTGTAACCTAGTTGGATTTTTTTGGGGGGGGAATGTATCAGAATCTAACGTGTCGTTAATAGAAA
GAAGAACAGGCAAGAAGTGGTCCAGCCGGCGAAGTTGCAGATCTGATCTCTTCTGAACACCTCATCGTGTCTCCATCCCTGGGAATCTGA
CCCTAGCAACTGGACCACTTTGTTCTTGGAATTTTGGGTGTCCTCTTTTCTCACCTTTCCCTTTTCCCTTTTCCCCTTCCCCCTCCTGAG
AACTCCGGAAGACTGTAGAGATTGTCATGGAGTCCAGGGAAACCTTAAGCAGCTCCCGGCAAAGAGGGGGCGAGTCAGACTTCCTGCCGG
TCTCCTCAGCCAAGCCCCCAGCTGCTCCTGGCTGTGCAGGAGAACCTTTGCTCTCCACTCCAGGACCTGGGAAGGGGATCCCGGTGGGCG
GAGAGCGCATGGAGCCAGAGGAGGAGGATGAACTAGGCTCAGGGCGGGATGTGGATTCCAACTCCAACGCGGACAGTGAGAAATGGGTGG
CAGGAGATGGTTTGGAAGAGCAGGAATTTTCTATCAAGGAGGCAAACTTCACAGAGGGAAGTCTGAAGCTAAAGATTCAGACCACAAAGC
GGGCTAAGAAACCCCCAAAGAATTTGGAGAACTATATATGTCCACCTGAGATCAAGATCACCATCAAGCAGTCTGGGGACCAGAAGGTGT
CCCGTGCTGGAAAAAATAGCAAAGCCACGAAGGAGGAAGAAAGAAGCCACTCCAAAAAGAAGCTCCTCACAGCCAGTGACCTTGCAGCCA
GTGACCTCAAAGGATTTCAGCCACAGATTTTAAATGGAGGGACTCCAGACATTCCTTCCAGTGGCCTACTATCAGGCCAGGCTCAGGAGA
ACCCAGGTTATCCATATTCTGATAGTTCTTCTATTCTTGGTGAGAACCCCCACATAGGTATAGACATGATTGACAACGACCAAGGATCAA
GTAGTCCCAGTAATGATGAGGCAGCAATGGCTGTCATCATGAGCCTCTTGGAAGCAGATGCTGGACTGGGTGGCCCTGTTGACTTTAGTG
ACTTGCCATGGCCGCTGTAAACACTACATGTTGCTTTGGCAACAGCTATAGTATCAAAGTGCATTACTGGTGGAGTTTTACAGTCTGTGA
AGCTTACTGGATAAGGAGAGAATAGCTTTTATGTACTGACTTCATAAAAGCCATCTCAGAGCCATTGATACAAGTCAATCTTACTATATG
TAACTTCAGACAAAGTGGAACTAAGCCTGCTCCAGTGTTTCCTCATCATTGATTATTGGGCTAGCTGTGGATAGCTTGCATTAATTGTAT
ATTTTGGATTCTGTTTGTGTTGAATTTTTTAATCATTGTGCACAGAAGCATCATTGGTAGCTTTTATATGCAAATGGTCATTTCAGATGT
ATGGTGTTTTTACACTACAAAGAAGTCCCCCATGTGGATATTTCTTATACTAATTGTATCATAAAGCCGTTTATTCTTCCTTGTAAGAAT


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FusionGenePPI for SETBP1_ARNTL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SETBP1SET, APP, PPP2CA, UBE2I, XAGE1E, YAF2, SETBP1, SPANXA1, KIAA1147, SPANXD, SPANXC, PLEKHF2, LRRC37A11P, SUMO1P1ARNTLNPAS4, CRY1, CLOCK, EP300, KAT2B, CSNK1E, NPAS2, RXRA, RARA, AHR, HSP90AA1, EPAS1, HIF1A, SIRT1, DYRK1B, UBE3A, CRY2, CSNK2B, DEC1, WDR5, RORC, PPP1CA, RHOU, CREBBP, BCAM, ARNTL2, LRFN4, MAX, RPRD1A, HAUS6, PHLDB3, PTRF, PHF21A, OIP5, CCDC93, CCDC132, HMG20A, RCOR1, GRIPAP1, DZIP3, VPS53, PSMD9, RABGAP1L, GOLGA5, TUFT1, YEATS4, CCHCR1, TFPT, NCKAP5L, PKN3, GIT2, KDM1A, NUF2, THAP11, RABGEF1, JUN, VPS51


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneARNTLchr18:42449248chr11:13407236ENST00000361003+1518508_588421509CIART
TgeneARNTLchr18:42449248chr11:13407236ENST00000401424+1720508_588496584CIART
TgeneARNTLchr18:42449248chr11:13407236ENST00000403510+1720508_588495583CIART


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneARNTLchr18:42449248chr11:13407236ENST00000389707+1720508_588538626CIART
TgeneARNTLchr18:42449248chr11:13407236ENST00000396441+1619508_588538626CIART
TgeneARNTLchr18:42449248chr11:13407236ENST00000403290+1720508_588539627CIART
TgeneARNTLchr18:42449248chr11:13407236ENST00000403482+1114508_588537625CIART


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SETBP1_ARNTL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SETBP1_ARNTL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSETBP1C0265227Schinzel-Giedion syndrome6CTD_human;ORPHANET;UNIPROT
HgeneSETBP1C3463824MYELODYSPLASTIC SYNDROME4UNIPROT
HgeneSETBP1C0023467Leukemia, Myelocytic, Acute2UNIPROT
HgeneSETBP1C0023473Myeloid Leukemia, Chronic2UNIPROT
HgeneSETBP1C0349639Juvenile Myelomonocytic Leukemia2CTD_human;UNIPROT
HgeneSETBP1C3714756Intellectual Disability2CTD_human;HPO
HgeneSETBP1C0023014Language Development Disorders1CTD_human
HgeneSETBP1C0023470Myeloid Leukemia1CTD_human
HgeneSETBP1C0043094Weight Gain1CTD_human
HgeneSETBP1C0376634Craniofacial Abnormalities1CTD_human
HgeneSETBP1C1292772Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative1CTD_human
HgeneSETBP1C1458155Mammary Neoplasms1CTD_human
TgeneARNTLC0005586Bipolar Disorder5PSYGENET
TgeneARNTLC0011570Mental Depression3PSYGENET
TgeneARNTLC0011581Depressive disorder3PSYGENET
TgeneARNTLC0525045Mood Disorders2PSYGENET
TgeneARNTLC0021361Female infertility1CTD_human
TgeneARNTLC0023473Myeloid Leukemia, Chronic1CTD_human
TgeneARNTLC0085159Seasonal Affective Disorder1PSYGENET
TgeneARNTLC0151744Myocardial Ischemia1CTD_human