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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 33251

FusionGeneSummary for SERINC2_ZCCHC17

check button Fusion gene summary
Fusion gene informationFusion gene name: SERINC2_ZCCHC17
Fusion gene ID: 33251
HgeneTgene
Gene symbol

SERINC2

ZCCHC17

Gene ID

347735

51538

Gene nameserine incorporator 2zinc finger CCHC-type containing 17
SynonymsFKSG84|PRO0899|TDE2|TDE2LHSPC251|PS1D|pNO40
Cytomap

1p35.2

1p35.2

Type of geneprotein-codingprotein-coding
Descriptionserine incorporator 2tumor differentially expressed protein 2nucleolar protein of 40 kDanucleolar protein 40pnn-interacting nucleolar proteinputative S1 RNA binding domain proteinzinc finger CCHC domain-containing protein 17zinc finger, CCHC domain containing 17
Modification date2018052320180522
UniProtAcc

Q96SA4

Q9NP64

Ensembl transtripts involved in fusion geneENST00000373710, ENST00000536859, 
ENST00000373709, ENST00000536384, 
ENST00000491976, 		ENST00000344147, 
ENST00000479629, ENST00000373714, 
ENST00000546109, ENST00000422613, 
Fusion gene scores* DoF score9 X 7 X 5=3155 X 8 X 3=120
# samples 118
** MAII scorelog2(11/315*10)=-1.51784830486262
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/120*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SERINC2 [Title/Abstract] AND ZCCHC17 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBLCATCGA-4Z-AA7Q-01ASERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
TCGARVLUSCTCGA-33-4566-01ASERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
TCGARVLUSCTCGA-66-2758-01ASERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
TCGALDLUSCTCGA-33-4566-01ASERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
TCGALDLUSCTCGA-66-2758-01ASERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000373710ENST00000344147SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373710ENST00000479629SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373710ENST00000373714SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373710ENST00000546109SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373710ENST00000422613SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
intron-3CDSENST00000536859ENST00000344147SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
intron-3UTRENST00000536859ENST00000479629SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
intron-3UTRENST00000536859ENST00000373714SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
intron-3UTRENST00000536859ENST00000546109SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
intron-3UTRENST00000536859ENST00000422613SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
Frame-shiftENST00000373709ENST00000344147SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373709ENST00000479629SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373709ENST00000373714SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373709ENST00000546109SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000373709ENST00000422613SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
Frame-shiftENST00000536384ENST00000344147SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000536384ENST00000479629SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000536384ENST00000373714SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000536384ENST00000546109SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000536384ENST00000422613SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
Frame-shiftENST00000491976ENST00000344147SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000491976ENST00000479629SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000491976ENST00000373714SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000491976ENST00000546109SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
5CDS-3UTRENST00000491976ENST00000422613SERINC2chr1

31907524

+ZCCHC17chr1

31811804

+
intron-3CDSENST00000373710ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000373710ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000373710ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000373710ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000373710ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-3CDSENST00000536859ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536859ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536859ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536859ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536859ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
Frame-shiftENST00000373709ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-3CDSENST00000536384ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536384ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536384ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536384ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000536384ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-3CDSENST00000491976ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000491976ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000491976ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000491976ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
intron-intronENST00000491976ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836879

+
In-frameENST00000373710ENST00000344147SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000479629SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000373714SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000546109SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000422613SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
In-frameENST00000536859ENST00000344147SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000479629SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000373714SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000546109SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000422613SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
In-frameENST00000373709ENST00000344147SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000479629SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000373714SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000546109SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000422613SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
In-frameENST00000536384ENST00000344147SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000479629SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000373714SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000546109SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000422613SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
3UTR-3CDSENST00000491976ENST00000344147SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000479629SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000373714SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000546109SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000422613SERINC2chr1

31901915

+ZCCHC17chr1

31836879

+
intron-intronENST00000373710ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000373710ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000373710ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000373710ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000373710ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536859ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536859ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536859ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536859ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536859ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
5CDS-intronENST00000373709ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
5CDS-intronENST00000373709ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
5CDS-intronENST00000373709ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
5CDS-intronENST00000373709ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
5CDS-intronENST00000373709ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536384ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536384ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536384ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536384ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000536384ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000491976ENST00000344147SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000491976ENST00000479629SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000491976ENST00000373714SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000491976ENST00000546109SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
intron-intronENST00000491976ENST00000422613SERINC2chr1

31886151

+ZCCHC17chr1

31836695

+
Frame-shiftENST00000373710ENST00000344147SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000479629SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000373714SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000546109SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373710ENST00000422613SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
Frame-shiftENST00000536859ENST00000344147SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000479629SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000373714SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000546109SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536859ENST00000422613SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
Frame-shiftENST00000373709ENST00000344147SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000479629SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000373714SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000546109SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000373709ENST00000422613SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
Frame-shiftENST00000536384ENST00000344147SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000479629SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000373714SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000546109SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
5CDS-intronENST00000536384ENST00000422613SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
3UTR-3CDSENST00000491976ENST00000344147SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000479629SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000373714SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000546109SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+
3UTR-intronENST00000491976ENST00000422613SERINC2chr1

31902385

+ZCCHC17chr1

31836879

+

Top

FusionProtFeatures for SERINC2_ZCCHC17


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SERINC2

Q96SA4

ZCCHC17

Q9NP64


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710131_150290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710160_182290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710202_224290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710239_256290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710268_290290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+71040_57290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+7105_27290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+71096_118290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811131_150299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811160_182299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811202_224299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811239_256299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811268_290299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+81140_57299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+8115_27299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+81196_118299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710131_150294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710160_182294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710202_224294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710239_256294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710268_290294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+71040_57294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+7105_27294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+71096_118294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710131_150294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710160_182294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710202_224294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710239_256294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710268_290294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+71040_57294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+7105_27294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+71096_118294460TransmembraneHelical
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000344147+68185_240188242Compositional biasNote=Lys-rich
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000373714+68185_240188242Compositional biasNote=Lys-rich

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710317_339290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710385_407290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373709+710422_444290456TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811317_339299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811385_407299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000373710+811422_444299465TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710317_339294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710385_407294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536384+710422_444294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710317_339294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710385_407294460TransmembraneHelical
HgeneSERINC2chr1:31901915chr1:31836879ENST00000536859+710422_444294460TransmembraneHelical
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000344147+68110_113188242Compositional biasNote=Poly-Arg
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000344147+68161_167188242Compositional biasNote=Poly-Glu
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000373714+68110_113188242Compositional biasNote=Poly-Arg
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000373714+68161_167188242Compositional biasNote=Poly-Glu
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000344147+6816_88188242DomainS1 motif
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000373714+6816_88188242DomainS1 motif
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000344147+68131_148188242Zinc fingerCCHC-type
TgeneZCCHC17chr1:31901915chr1:31836879ENST00000373714+68131_148188242Zinc fingerCCHC-type


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FusionGeneSequence for SERINC2_ZCCHC17


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for SERINC2_ZCCHC17


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SERINC2ATP6V0A2, ATP6V0A1, GHITM, ATP6V0D1, STOM, TMBIM6, LGALS3, GPR89BZCCHC17SDCBP2, PNN, CACNA1A, APP, JMJD6, HECW2, KDM1A, SUV39H1, SDCBP, ZDHHC17, ZBTB38, SRPK2, PFKFB2, SAP30, PTTG1, ZMYND8, LAP3, ING3, KIAA1598, CSNK2A2, H2AFY2, SSFA2, CDX1, NOS1AP, HIST1H1T, CSNK2A1, NKAP, ZNF512, MECP2, RNPS1, FTL, BPIFB1, MDK, RRP8, RBM4, IGJ, KNOP1, SRRM2, ZC3H14, IGHA1, POF1B


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SERINC2_ZCCHC17


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SERINC2_ZCCHC17


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSERINC2C0001973Alcoholic Intoxication, Chronic1PSYGENET