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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 33107

FusionGeneSummary for SECISBP2_NEDD4L

check button Fusion gene summary
Fusion gene informationFusion gene name: SECISBP2_NEDD4L
Fusion gene ID: 33107
HgeneTgene
Gene symbol

SECISBP2

NEDD4L

Gene ID

79048

23327

Gene nameSECIS binding protein 2neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
SynonymsSBP2NEDD4-2|NEDD4.2|PVNH7|RSP5|hNEDD4-2
Cytomap

9q22.2

18q21.31

Type of geneprotein-codingprotein-coding
Descriptionselenocysteine insertion sequence-binding protein 2Sec insertion sequence-binding protein 2E3 ubiquitin-protein ligase NEDD4-likeHECT-type E3 ubiquitin transferase NED4Lubiquitin-protein ligase Rsp5
Modification date2018052320180523
UniProtAcc

Q96T21

Q96PU5

Ensembl transtripts involved in fusion geneENST00000375807, ENST00000339901, 
ENST00000534113, ENST00000470305, 
ENST00000356462, ENST00000400345, 
ENST00000589054, ENST00000256832, 
ENST00000382850, ENST00000256830, 
ENST00000588516, ENST00000456986, 
ENST00000435432, ENST00000357895, 
ENST00000586263, ENST00000456173, 
ENST00000431212, 
Fusion gene scores* DoF score5 X 6 X 2=6013 X 14 X 6=1092
# samples 616
** MAII scorelog2(6/60*10)=0log2(16/1092*10)=-2.77082904603249
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SECISBP2 [Title/Abstract] AND NEDD4L [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneNEDD4L

GO:0003254

regulation of membrane depolarization

15217910

TgeneNEDD4L

GO:0006511

ubiquitin-dependent protein catabolic process

21463633

TgeneNEDD4L

GO:0010038

response to metal ion

11244092

TgeneNEDD4L

GO:0016567

protein ubiquitination

15217910|25631046

TgeneNEDD4L

GO:0034765

regulation of ion transmembrane transport

17289006

TgeneNEDD4L

GO:0042391

regulation of membrane potential

17289006

TgeneNEDD4L

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

21463633

TgeneNEDD4L

GO:0060306

regulation of membrane repolarization

21463633

TgeneNEDD4L

GO:0070936

protein K48-linked ubiquitination

21463633

TgeneNEDD4L

GO:1901016

regulation of potassium ion transmembrane transporter activity

17289006

TgeneNEDD4L

GO:1901017

negative regulation of potassium ion transmembrane transporter activity

21463633

TgeneNEDD4L

GO:1901380

negative regulation of potassium ion transmembrane transport

21463633

TgeneNEDD4L

GO:1902306

negative regulation of sodium ion transmembrane transport

15217910

TgeneNEDD4L

GO:1903861

positive regulation of dendrite extension

23999003

TgeneNEDD4L

GO:2000009

negative regulation of protein localization to cell surface

21463633

TgeneNEDD4L

GO:2000650

negative regulation of sodium ion transmembrane transporter activity

15217910


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUADTCGA-86-8075-01ASECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000375807ENST00000356462SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000375807ENST00000400345SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000375807ENST00000589054SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000375807ENST00000256832SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
In-frameENST00000375807ENST00000382850SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000375807ENST00000256830SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000375807ENST00000588516SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000375807ENST00000456986SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000375807ENST00000435432SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000375807ENST00000357895SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000375807ENST00000586263SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000375807ENST00000456173SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000375807ENST00000431212SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
In-frameENST00000339901ENST00000356462SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000339901ENST00000400345SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000339901ENST00000589054SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000339901ENST00000256832SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
In-frameENST00000339901ENST00000382850SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000339901ENST00000256830SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000339901ENST00000588516SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000339901ENST00000456986SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000339901ENST00000435432SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000339901ENST00000357895SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000339901ENST00000586263SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000339901ENST00000456173SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000339901ENST00000431212SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
In-frameENST00000534113ENST00000356462SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000534113ENST00000400345SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000534113ENST00000589054SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000534113ENST00000256832SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
In-frameENST00000534113ENST00000382850SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
Frame-shiftENST00000534113ENST00000256830SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000534113ENST00000588516SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000534113ENST00000456986SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000534113ENST00000435432SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000534113ENST00000357895SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000534113ENST00000586263SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000534113ENST00000456173SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
5CDS-intronENST00000534113ENST00000431212SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-3CDSENST00000470305ENST00000356462SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-3CDSENST00000470305ENST00000400345SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-3CDSENST00000470305ENST00000589054SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-3CDSENST00000470305ENST00000256832SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-3CDSENST00000470305ENST00000382850SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-3CDSENST00000470305ENST00000256830SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-intronENST00000470305ENST00000588516SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-intronENST00000470305ENST00000456986SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-intronENST00000470305ENST00000435432SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-intronENST00000470305ENST00000357895SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-intronENST00000470305ENST00000586263SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-intronENST00000470305ENST00000456173SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+
intron-intronENST00000470305ENST00000431212SECISBP2chr9

91956394

+NEDD4Lchr18

56063399

+

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FusionProtFeatures for SECISBP2_NEDD4L


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SECISBP2

Q96T21

NEDD4L

Q96PU5

Binds to the SECIS element in the 3'-UTR of some mRNAsencoding selenoproteins. Binding is stimulated by SELB.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSECISBP2chr9:91956394chr18:56063399ENST00000339901+1017380_387405782Compositional biasNote=Poly-Lys
HgeneSECISBP2chr9:91956394chr18:56063399ENST00000375807+1017380_387478855Compositional biasNote=Poly-Lys

- In-frame and not-retained protein feature among the 13 regional features.
>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSECISBP2chr9:91956394chr18:56063399ENST00000339901+1017673_694405782RegionRNA-binding
HgeneSECISBP2chr9:91956394chr18:56063399ENST00000375807+1017673_694478855RegionRNA-binding
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000256830+2628193_226837872DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000256830+2628385_418837872DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000256830+2628497_530837872DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000256830+2628548_581837872DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000256830+2628640_974837872DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000256830+26287_109837872DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000356462+2729193_226877912DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000356462+2729385_418877912DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000356462+2729497_530877912DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000356462+2729548_581877912DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000356462+2729640_974877912DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000356462+27297_109877912DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000357895+2931193_226933968DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000357895+2931385_418933968DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000357895+2931497_530933968DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000357895+2931548_581933968DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000357895+2931640_974933968DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000357895+29317_109933968DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000382850+2830193_226921956DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000382850+2830385_418921956DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000382850+2830497_530921956DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000382850+2830548_581921956DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000382850+2830640_974921956DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000382850+28307_109921956DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000400345+2931193_226941976DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000400345+2931385_418941976DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000400345+2931497_530941976DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000400345+2931548_581941976DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000400345+2931640_974941976DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000400345+29317_109941976DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000431212+2830193_226820855DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000431212+2830385_418820855DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000431212+2830497_530820855DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000431212+2830548_581820855DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000431212+2830640_974820855DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000431212+28307_109820855DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000435432+2931193_226800835DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000435432+2931385_418800835DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000435432+2931497_530800835DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000435432+2931548_581800835DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000435432+2931640_974800835DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000435432+29317_109800835DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456173+2729193_226800835DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456173+2729385_418800835DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456173+2729497_530800835DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456173+2729548_581800835DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456173+2729640_974800835DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456173+27297_109800835DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456986+2931193_226820855DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456986+2931385_418820855DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456986+2931497_530820855DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456986+2931548_581820855DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456986+2931640_974820855DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000456986+29317_109820855DomainC2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000586263+2830193_226913948DomainWW 1
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000586263+2830385_418913948DomainWW 2
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000586263+2830497_530913948DomainWW 3
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000586263+2830548_581913948DomainWW 4
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000586263+2830640_974913948DomainHECT
TgeneNEDD4Lchr9:91956394chr18:56063399ENST00000586263+28307_109913948DomainC2


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FusionGeneSequence for SECISBP2_NEDD4L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SECISBP2_ENST00000375807_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_512aa
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEQKIYTEDMAFGASTFPPQYLSSEITLHPY
AYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHH
LSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDISLLREVVKPAAVLSKGEI
VVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHP
TQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQL

>In-frame_SECISBP2_ENST00000375807_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_512aa
MASEGPREPESEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEQKIYTEDMAFGASTFPPQYLSSEITLHPY
AYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHH
LSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDISLLREVVKPAAVLSKGEI
VVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHP
TQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQL

>In-frame_SECISBP2_ENST00000339901_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_439aa
MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSER
ADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDIS
LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSE
ALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQP

>In-frame_SECISBP2_ENST00000339901_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_439aa
MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSER
ADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDIS
LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVSIPSSE
ALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQP

>In-frame_SECISBP2_ENST00000534113_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_444aa
MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQK
FDSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVS
IPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ

>In-frame_SECISBP2_ENST00000534113_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_444aa
MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTCPLPQEMKALFKKKTYDEKKTYDQQK
FDSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIASSADPKNVS
IPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SECISBP2_ENST00000375807_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_1538nt
ATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTC
AATGTGGCATGGTTAGAGTCCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACA
GAGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATAT
GCCTATTCTCCTTATACCCTTGACTCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGA
GGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAG
AAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCAT
TTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCT
ACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCC
AAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATA
GTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATG
GGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCA
TCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCT
ACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCA
AAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGAC
AGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTG
GACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTA
ATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGGG

>In-frame_SECISBP2_ENST00000375807_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_1538nt
ATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTC
AATGTGGCATGGTTAGAGTCCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACA
GAGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATAT
GCCTATTCTCCTTATACCCTTGACTCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGA
GGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAG
AAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCAT
TTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCT
ACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCC
AAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATA
GTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATG
GGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCA
TCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCT
ACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCA
AAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGAC
AGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTG
GACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTA
ATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGGG

>In-frame_SECISBP2_ENST00000339901_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_1319nt
ATGGTTAGAGTCCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAAATGTT
TACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGC
CCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGG
GCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGT
TACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTT
CCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCT
CTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAAT
GCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCA
GCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAA
GCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAA
CAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATT
GAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCA
CAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAG
CACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATT

>In-frame_SECISBP2_ENST00000339901_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_1319nt
ATGGTTAGAGTCCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAAATGTT
TACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGC
CCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGG
GCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGT
TACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTT
CCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCT
CTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAAT
GCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCA
GCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAA
GCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAA
CAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATT
GAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCA
CAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAG
CACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATT

>In-frame_SECISBP2_ENST00000534113_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_1334nt
ATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGAC
TCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGCATCGA
AATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAG
TTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGAATAGT
TTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTT
ACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACTCTGTC
TCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAA
TCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGACATTA
TCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGT
ATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCATCACAA
GGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAA
GAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAATTTCAA
TCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCC
CTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCCATATG

>In-frame_SECISBP2_ENST00000534113_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_1334nt
ATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGAC
TCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGCATCGA
AATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAG
TTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGAATAGT
TTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTT
ACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACTCTGTC
TCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAA
TCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGACATTA
TCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGT
ATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCATCACAA
GGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAA
GAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAATTTCAA
TCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCC
CTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCCATATG


* Fusion transcript sequences (Full-length transcript).
>In-frame_SECISBP2_ENST00000375807_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_1914nt
GCTTTGTCTGTCCGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGC
GGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGT
CCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAGCAGAAAATATATACTG
AAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCC
TTGACTCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGC
ATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGC
AAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGA
ATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTG
AATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACT
CTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAA
ATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGA
CATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATG
TTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCAT
CACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAG
TTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAAT
TTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGA
CAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCC
ATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGGGTGGATTAAGCACCCTGTGC
CTCGGGGGTGGTTGTTCTTCAAGCAAGTTCTGCTTGCACTTTTGCATTTGCCTAACAGACTTTTGCAGAGGCGATGGCAGAGAGCAGCTG
CAGGCATGGTCCCTGGAGCCGAGCCTTCACCACGCACTCGTCCAAGTTCGGATGCGGGAACCTGGTCCCAGCTTGAGTTCCTGCCTTTCC
CACCACAAATTATCAACTGGTTGATGTGTACACTAATTACATTTCAGGAGGACTTAATGCTATTTATGTTGTGCCTCTGCAGGCAAAGCC

>In-frame_SECISBP2_ENST00000375807_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_6879nt
GCTTTGTCTGTCCGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGC
GGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGT
CCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAGCAGAAAATATATACTG
AAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCC
TTGACTCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGC
ATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGC
AAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGA
ATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTG
AATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACT
CTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAA
ATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGA
CATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATG
TTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCAT
CACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAG
TTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAAT
TTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGA
CAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCC
ATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGGGTGGATTAAGCACCCTGTGC
CTCGGGGGTGGTTGTTCTTCAAGCAAGTTCTGCTTGCACTTTTGCATTTGCCTAACAGACTTTTGCAGAGGCGATGGCAGAGAGCAGCTG
CAGGCATGGTCCCTGGAGCCGAGCCTTCACCACGCACTCGTCCAAGTTCGGATGCGGGAACCTGGTCCCAGCTTGAGTTCCTGCCTTTCC
CACCACAAATTATCAACTGGTTGATGTGTACACTAATTACATTTCAGGAGGACTTAATGCTATTTATGTTGTGCCTCTGCAGGCAAAGCC
CTTAATAAATATTTTACATCCTTTCTAATGACAATGAATGGAATTAATCACTCAACAGGTATAGTATTACGACTCATGTTTACTTTTTAA
AATGATTTAGACCGATTTTCAGATTTTATTTCGTTATGATTAAAGATGTCTCATGTACTTGGAAAAGTGAGCATTTTTTTTTTTTTTGTA
TTTCACTTTCATACCAGGCTTAATGTCAATGACATTTTTATTTTTGAAGTACTCTGACACCTCCACCCTCTACTTTATTAGAATTGGAAG
GCAAATTTTTGTCCAAAAACCTACAGACAAGTACTTTGAGAGAATTTCCAATATAATATTAGACATAATGATAATTTTTTCCATACTCAG
AATGAAAAACTGGATATTACGTTTTTGTTTTGGGGTTTTTTTGTACAAATTTAGCTAATAGCTACAGGCTGAGAGAATTGTAACATAGCA
TGACAAATTTTGTGTTGACTTGAAAGGAATCACACCATTATTCCTTAGAAGTAATTACATGTGTTCTAACACATTTGAGACAGGGTTGGA
CTCCCATTTCTCATCCGAGAAATTACTTAACCCTTCCTGGCGCTGTACAGTCATCTTTTATTCTATTTCCTCTTTGCTGTTTGTAGTAGA
GACATTTTGAATGAAACTTGGCACTGCTTGATTCAAAACTGTGGAAACCAGATCTGTTTAGTCTCCTGTTTGTATGCGTTTGCTAATGGT
AGCTAAATAACCAGTTTTTGTTGTAAATGCACCAATTCTGAAGGCACTTTATGTACTACATGGAGGTCATATCTGGTTTTGTTTTTATTT
TTTTATCATGAACATTAAATGTGATGATGATTTCTTTTCCCTGCACACATCTTTCCGGTGCAATATCTATCAATTGTGAATCTGGCTGCT
GGTGTATAAAAACCTGGATGTAAAGCTGAGCCTACAGACCTGTCCTCACCAACTGTTTTGTGATTTCTACTCAACTACAAAGATTTATTT
AATGTACTCTTAATCTAACTGAGTTTTGTTACCAATGACCTGTTGCATGCTTCAATACCGTGTACTGCCTGAGTTGTGCCTCTTGTGTGC
TAGATTAAAAGTGAGACAGAGACTTGACTTGATCCTCTGAGCTCAAGCTATTGAGCTGGTAGTGGCAGAGGACTGAGGGTACCTGCACAG
TTTGATTCTTTTCCACGTGTAAGTCTCCATTGCAGAATTGTCGTGCTTTGAGAAAACACCTGAGGCAGTGTGGGAGTTGAACGACCCTGC
TGTCCTTTTTAACCTGTGTTGTCCTAGACCCTGTCGGGGCAGTCAGGGGACACTAGAGATTTGATCTCATGCGAGTCATCAATAGGACAA
AAAAGTTGTGGTTTGGGGAGGTCTGTTTGTTACATAAAAAGGACCTTTCGGTGTAAGAAATTGCCGTTTTTACCCTGCCCTGGCTGGCAT
GTGAGAAGCCATGGAAGGTTGTGGTTGTAAATGAGTTGTCTAAAGGGGTGCAGAGGCCTGAGGTTTCTAAAAGAAGGTAGATTTCTACAG
AGCTGAGTGTTGGTTCCTTTTTCTTATTGGTTGAAAATTACCTGGTAGTGATCAGAAAACTTAGATGCTATGTAACTAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAATTCCCGCTCATGAGTTTTGACTATTGGTGAGATGTTTTCCGCTACAGTTAACATGACAAATGTCTC
AGTGGCAAAAATCCCCTTTTTGTAAGCCCCCATAGTCTAGAGGCAGTTTTCTTTTTAAGAATCATGCCAGAGCCTGAGTCGAGCAGTATG
CTTTCTTGGTTTTTGAGAGTAATTGTGTAATTGTAGAGGGAGAAATCCAATTCTAACCTAAGAACTGGGATTCTTCTGTCATCTTGTAAA
CCGTATATTGAAAAAAACAGAATGTCACTAAATGCATATTAAGTCAAGTATTGGAAAGTATAAAAGAAAAATCATTCTGACAATTTCTAA
GCCAGAAGCAAACAAGAATTACTGAAATCTACCCCATGAATACTTGGAAGGCAGTAATTGTGAGTGACACCTCAGTTCATCAACCCCTTA
ATAATATCAGCTTAATTTTAATGACAACTAAATATGCTGAAGTGAGGATTTAGTATTTTTTAAAAAAGCAAAACAAGGTTCAGTAGTCCT
CAGCAATTCTCCAAGTTTCTCTCTTTGCCTAAAATGGTCATAGATCTTGATTTCTCTGAATCGTGATGACCACACCCAGTCATCTTCACA
GCATAATTGCAGGTGGCAGTAAAGAGAGTGTGCTGGGTAAGGAGCAGTTGCTGGGTCATTCCTTGGGCCCCGACCTGCCCGGGGAGTAGC
CCTGGGGGAGAGAGGGCAGTGTTGCCTATCCCAGAGGTCCCAGCAGTCACACTGCTCTGCAGGCCGGGCTCTCTTTATAGCCAGAGAAAT
CACCTTAATGCAGTCTCTTTAGTTGTCTGCTGAAGCTGTAGTTATTATGGGCCACTTACATGAGGCTGAGAAGTACGTGCCGGAGCTCAC
ACACTGCCTGTTGCGGTTCTCTTAACATCAGTTATCACAGCTGCCTGTGGGTCCCGGGTATTTCCATTCCTGCCCCTTGTTGGCCCGAGG
AAGGATGTGGAAAGAGCACCTGGTGGGATGAAGGTCCAACAGCCTGTGCCTCTCCACTGCTGGCCCTGGAGCCGGCAGCAGTGAGGCATT
CATTGTCTGTGTTGCGGTGTATTCCCAGCTTCAGTGCTCTTTTCCTTTTTGCCTGAAATGTTTATGCTTCTCTGCAGCCAGTCCTCTAAC
AAATCTCAAGAACAAAGGTAAGACACTTGGTTTTTGTTTCCAGGACCCTTCAGAAGGTGACATCAGATATTCCCTAAATTCAGACAATGA
GGGATACAGAGCGACTTGGCATGTATTATTTCTCCCATGTAAGGACAAAGGGACAGATTATTATTGTTATTTCTGAGACAGAGTCTTGCT
CTGTAGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACCACAACCTCTGCCTCCTGGCTTCAAGCGATTCTTCTGCCTCAGCCTCC
CCGAATAGTTGGGATTACAGGCACCCACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGTTTCACCATGCTGGCCAGGCTG
GTCTTGAACTCCTGACCTCAGGTGATCCTCCCGCCTCAGCCTTCCAAAGTGCTGGGATTACAAGCATGAGCCACCGCACCCGGCCTCACA
GTGACAGATTCTGAGAAACAGCATGCAAAACATTTGAACCATTTTCTACATCTCCCATTGTTGCATAGAGAGTGTGCACCGCTGCTATCT
TGCCAGATCCACACTGGTCCTCCCGAAAGCCAGGTTCATACACAGCAACTTTTTAATTATTCTAACAGTTACCCATTAACAGTCGACTCC
TGTATTTCTGAGAGTCTTGTACTCACCTCTGAAATTTAAAAACGTATAAAGAGAGCCTGGGTTAATCAGTTCTGCAGCCCCTACGTGACA
CTGTGCTAGTTCTCCTTCTTCTGTCTCCTCCTTACCCTGGCCCTGCACCCCTGTACTTAAGAGGGAGAGGTGGGAGGTGCTGTCTGGTAT
CATTTGCTGCCTCGCCAGTAGAGGGTGCCGCTGTGCAGGGTAACTGCCCGCCTGCTCCCTTCCTGACCTCCCCTGACCCCGAAGATCACT
ACCTCTGTCATTCAGGCATTGGGGTACATCCTGATAAGTCGTGTCAGAACTGCCAATTTCAGGACTGAGATGTGTTTTTAAAAAACAAAT
CCTTATAAACTCCACTTTGTACTTTAGATTTTAAAACTGGGGAAAAATGTGATATTCTTTGGACCACTTTTTTAATTTATATAAGCCTTA
ATGAACAGTGTCTATACATTTGCATACACACACCCCCACCCCAGAGTGTTCTCAGTATGTCAGAGAAAGTGCCACAGCATTAGGACGGGA
GCTTGGAGAACGTTTTCTAGAAAAGGGTTAGCTTCCTGTTGGCATGAAATTTTCCAAGCAAACCTCATTAAACATCTGTTGTTTGTTAAA
GATGTTCCACTGAAAGCAACGCATGTTTCAAAGGCACGTCTTTCCGTTCGTTGGTTTTCTGTGTGTAAGGAGTAGCATTGCTGTTGGCGC
CTAACCTCGCGTGCACTGCATTCTCAACCCCGTACCAGTGCATCATCAGAAGCCTTCCTCGTGACCATAACTCTGTGTCTGCAGATATGT
GTTCCCGTGTAAGCCAGTTTTCCCCTTTTACTCAGACTGATTTCACCTAGATTGTCACGGTTTCCTTCATGTTAACTTTGCGTGACTTTG
TTCTTCCTTTACTACTCTGTATGTAATATATATACATATATACGTACATATGCTGTCCAAATATATTTGTATATATTTGTATAGCATTTT
TACACCTTTATTGAGTAATCTGGTTTCGAAAGGAGGTGAGAGTTTAGTCCCTTCTGCAGTTTTCTCCAAGCTGTGTCCTGTGAATTTCAA
CCCTTGGAGCCTAAGAAAACCCTAGGAAGATGATGTTAATTTGCTGTCATTTCCTAATTCAGGATCTATCATCAAATGAAACATGAAAAA
AACAGTGACTTTTAAGGTGAAAAGAGTTTCAAGCATTCCAAATAAATTATCAATGTTTCATAACTTTTTATTATAAACCCACCTCCTAAT
AGGAAGCCAAGTACTATTTGATACAGTGGTAAAAACCAAACTACCTTGAATTTTTTTAAGGCAACTTATGAATAATGCTCATTTTCACAG
TCAGAATAGCTTTAAAATATGGTTGAATTTGATACACACAGGAAGTTTTCTTGAAGAACAATCCTTTCGCTTTTCTTTTTTCTTGAGAGA
TCTAAAGAGAAACTGTAGATTGTTTTCCTGACAGCAAAAGACTAATGTGACAAAATGAAGTCATTGTAAAGAAGCGATGCAACTTGTCAA

>In-frame_SECISBP2_ENST00000339901_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_1780nt
GGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAG
CGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCATG
TGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAAATGTTTACTCAGTGCCTGGCTCCCAGTAT
CTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCT
CTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAG
ATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAA
TCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAAC
AATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCA
GCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGT
ACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCT
ATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTAC
AACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAAT
AAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAAC
CTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTA
AAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCC
TCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCG
TGGAAAATGCTCAAGGATTTGAAGGGGTGGATTAAGCACCCTGTGCCTCGGGGGTGGTTGTTCTTCAAGCAAGTTCTGCTTGCACTTTTG
CATTTGCCTAACAGACTTTTGCAGAGGCGATGGCAGAGAGCAGCTGCAGGCATGGTCCCTGGAGCCGAGCCTTCACCACGCACTCGTCCA
AGTTCGGATGCGGGAACCTGGTCCCAGCTTGAGTTCCTGCCTTTCCCACCACAAATTATCAACTGGTTGATGTGTACACTAATTACATTT

>In-frame_SECISBP2_ENST00000339901_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_6745nt
GGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAG
CGAGGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCATG
TGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAGAAATGTTTACTCAGTGCCTGGCTCCCAGTAT
CTTTATAACCAACCCAGTTGTTACCGAGGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCT
CTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAG
ATAAAATCAGCTAGAGGTTCACATCATTTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAA
TCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAAC
AATATGTCAGAGATACAGAAGCAACCCAAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCA
GCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGT
ACAAGAGAGTTATCTTGGACACCAATGGGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCT
ATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTAC
AACAAAGAAAAACACATTATTCATCCTACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAAT
AAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAAC
CTGGCAGTTGCATCTGAAAGAAGAGACAGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTA
AAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCC
TCCAAACCAGTGGTAGTCTCAGCTTTAATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCG
TGGAAAATGCTCAAGGATTTGAAGGGGTGGATTAAGCACCCTGTGCCTCGGGGGTGGTTGTTCTTCAAGCAAGTTCTGCTTGCACTTTTG
CATTTGCCTAACAGACTTTTGCAGAGGCGATGGCAGAGAGCAGCTGCAGGCATGGTCCCTGGAGCCGAGCCTTCACCACGCACTCGTCCA
AGTTCGGATGCGGGAACCTGGTCCCAGCTTGAGTTCCTGCCTTTCCCACCACAAATTATCAACTGGTTGATGTGTACACTAATTACATTT
CAGGAGGACTTAATGCTATTTATGTTGTGCCTCTGCAGGCAAAGCCCTTAATAAATATTTTACATCCTTTCTAATGACAATGAATGGAAT
TAATCACTCAACAGGTATAGTATTACGACTCATGTTTACTTTTTAAAATGATTTAGACCGATTTTCAGATTTTATTTCGTTATGATTAAA
GATGTCTCATGTACTTGGAAAAGTGAGCATTTTTTTTTTTTTTGTATTTCACTTTCATACCAGGCTTAATGTCAATGACATTTTTATTTT
TGAAGTACTCTGACACCTCCACCCTCTACTTTATTAGAATTGGAAGGCAAATTTTTGTCCAAAAACCTACAGACAAGTACTTTGAGAGAA
TTTCCAATATAATATTAGACATAATGATAATTTTTTCCATACTCAGAATGAAAAACTGGATATTACGTTTTTGTTTTGGGGTTTTTTTGT
ACAAATTTAGCTAATAGCTACAGGCTGAGAGAATTGTAACATAGCATGACAAATTTTGTGTTGACTTGAAAGGAATCACACCATTATTCC
TTAGAAGTAATTACATGTGTTCTAACACATTTGAGACAGGGTTGGACTCCCATTTCTCATCCGAGAAATTACTTAACCCTTCCTGGCGCT
GTACAGTCATCTTTTATTCTATTTCCTCTTTGCTGTTTGTAGTAGAGACATTTTGAATGAAACTTGGCACTGCTTGATTCAAAACTGTGG
AAACCAGATCTGTTTAGTCTCCTGTTTGTATGCGTTTGCTAATGGTAGCTAAATAACCAGTTTTTGTTGTAAATGCACCAATTCTGAAGG
CACTTTATGTACTACATGGAGGTCATATCTGGTTTTGTTTTTATTTTTTTATCATGAACATTAAATGTGATGATGATTTCTTTTCCCTGC
ACACATCTTTCCGGTGCAATATCTATCAATTGTGAATCTGGCTGCTGGTGTATAAAAACCTGGATGTAAAGCTGAGCCTACAGACCTGTC
CTCACCAACTGTTTTGTGATTTCTACTCAACTACAAAGATTTATTTAATGTACTCTTAATCTAACTGAGTTTTGTTACCAATGACCTGTT
GCATGCTTCAATACCGTGTACTGCCTGAGTTGTGCCTCTTGTGTGCTAGATTAAAAGTGAGACAGAGACTTGACTTGATCCTCTGAGCTC
AAGCTATTGAGCTGGTAGTGGCAGAGGACTGAGGGTACCTGCACAGTTTGATTCTTTTCCACGTGTAAGTCTCCATTGCAGAATTGTCGT
GCTTTGAGAAAACACCTGAGGCAGTGTGGGAGTTGAACGACCCTGCTGTCCTTTTTAACCTGTGTTGTCCTAGACCCTGTCGGGGCAGTC
AGGGGACACTAGAGATTTGATCTCATGCGAGTCATCAATAGGACAAAAAAGTTGTGGTTTGGGGAGGTCTGTTTGTTACATAAAAAGGAC
CTTTCGGTGTAAGAAATTGCCGTTTTTACCCTGCCCTGGCTGGCATGTGAGAAGCCATGGAAGGTTGTGGTTGTAAATGAGTTGTCTAAA
GGGGTGCAGAGGCCTGAGGTTTCTAAAAGAAGGTAGATTTCTACAGAGCTGAGTGTTGGTTCCTTTTTCTTATTGGTTGAAAATTACCTG
GTAGTGATCAGAAAACTTAGATGCTATGTAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTCCCGCTCATGAGTTTTGA
CTATTGGTGAGATGTTTTCCGCTACAGTTAACATGACAAATGTCTCAGTGGCAAAAATCCCCTTTTTGTAAGCCCCCATAGTCTAGAGGC
AGTTTTCTTTTTAAGAATCATGCCAGAGCCTGAGTCGAGCAGTATGCTTTCTTGGTTTTTGAGAGTAATTGTGTAATTGTAGAGGGAGAA
ATCCAATTCTAACCTAAGAACTGGGATTCTTCTGTCATCTTGTAAACCGTATATTGAAAAAAACAGAATGTCACTAAATGCATATTAAGT
CAAGTATTGGAAAGTATAAAAGAAAAATCATTCTGACAATTTCTAAGCCAGAAGCAAACAAGAATTACTGAAATCTACCCCATGAATACT
TGGAAGGCAGTAATTGTGAGTGACACCTCAGTTCATCAACCCCTTAATAATATCAGCTTAATTTTAATGACAACTAAATATGCTGAAGTG
AGGATTTAGTATTTTTTAAAAAAGCAAAACAAGGTTCAGTAGTCCTCAGCAATTCTCCAAGTTTCTCTCTTTGCCTAAAATGGTCATAGA
TCTTGATTTCTCTGAATCGTGATGACCACACCCAGTCATCTTCACAGCATAATTGCAGGTGGCAGTAAAGAGAGTGTGCTGGGTAAGGAG
CAGTTGCTGGGTCATTCCTTGGGCCCCGACCTGCCCGGGGAGTAGCCCTGGGGGAGAGAGGGCAGTGTTGCCTATCCCAGAGGTCCCAGC
AGTCACACTGCTCTGCAGGCCGGGCTCTCTTTATAGCCAGAGAAATCACCTTAATGCAGTCTCTTTAGTTGTCTGCTGAAGCTGTAGTTA
TTATGGGCCACTTACATGAGGCTGAGAAGTACGTGCCGGAGCTCACACACTGCCTGTTGCGGTTCTCTTAACATCAGTTATCACAGCTGC
CTGTGGGTCCCGGGTATTTCCATTCCTGCCCCTTGTTGGCCCGAGGAAGGATGTGGAAAGAGCACCTGGTGGGATGAAGGTCCAACAGCC
TGTGCCTCTCCACTGCTGGCCCTGGAGCCGGCAGCAGTGAGGCATTCATTGTCTGTGTTGCGGTGTATTCCCAGCTTCAGTGCTCTTTTC
CTTTTTGCCTGAAATGTTTATGCTTCTCTGCAGCCAGTCCTCTAACAAATCTCAAGAACAAAGGTAAGACACTTGGTTTTTGTTTCCAGG
ACCCTTCAGAAGGTGACATCAGATATTCCCTAAATTCAGACAATGAGGGATACAGAGCGACTTGGCATGTATTATTTCTCCCATGTAAGG
ACAAAGGGACAGATTATTATTGTTATTTCTGAGACAGAGTCTTGCTCTGTAGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACCA
CAACCTCTGCCTCCTGGCTTCAAGCGATTCTTCTGCCTCAGCCTCCCCGAATAGTTGGGATTACAGGCACCCACCACCACGCCTGGCTAA
TTTTTGTATTTTTAGTAGAGATGGTTTCACCATGCTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCTCCCGCCTCAGCCTTC
CAAAGTGCTGGGATTACAAGCATGAGCCACCGCACCCGGCCTCACAGTGACAGATTCTGAGAAACAGCATGCAAAACATTTGAACCATTT
TCTACATCTCCCATTGTTGCATAGAGAGTGTGCACCGCTGCTATCTTGCCAGATCCACACTGGTCCTCCCGAAAGCCAGGTTCATACACA
GCAACTTTTTAATTATTCTAACAGTTACCCATTAACAGTCGACTCCTGTATTTCTGAGAGTCTTGTACTCACCTCTGAAATTTAAAAACG
TATAAAGAGAGCCTGGGTTAATCAGTTCTGCAGCCCCTACGTGACACTGTGCTAGTTCTCCTTCTTCTGTCTCCTCCTTACCCTGGCCCT
GCACCCCTGTACTTAAGAGGGAGAGGTGGGAGGTGCTGTCTGGTATCATTTGCTGCCTCGCCAGTAGAGGGTGCCGCTGTGCAGGGTAAC
TGCCCGCCTGCTCCCTTCCTGACCTCCCCTGACCCCGAAGATCACTACCTCTGTCATTCAGGCATTGGGGTACATCCTGATAAGTCGTGT
CAGAACTGCCAATTTCAGGACTGAGATGTGTTTTTAAAAAACAAATCCTTATAAACTCCACTTTGTACTTTAGATTTTAAAACTGGGGAA
AAATGTGATATTCTTTGGACCACTTTTTTAATTTATATAAGCCTTAATGAACAGTGTCTATACATTTGCATACACACACCCCCACCCCAG
AGTGTTCTCAGTATGTCAGAGAAAGTGCCACAGCATTAGGACGGGAGCTTGGAGAACGTTTTCTAGAAAAGGGTTAGCTTCCTGTTGGCA
TGAAATTTTCCAAGCAAACCTCATTAAACATCTGTTGTTTGTTAAAGATGTTCCACTGAAAGCAACGCATGTTTCAAAGGCACGTCTTTC
CGTTCGTTGGTTTTCTGTGTGTAAGGAGTAGCATTGCTGTTGGCGCCTAACCTCGCGTGCACTGCATTCTCAACCCCGTACCAGTGCATC
ATCAGAAGCCTTCCTCGTGACCATAACTCTGTGTCTGCAGATATGTGTTCCCGTGTAAGCCAGTTTTCCCCTTTTACTCAGACTGATTTC
ACCTAGATTGTCACGGTTTCCTTCATGTTAACTTTGCGTGACTTTGTTCTTCCTTTACTACTCTGTATGTAATATATATACATATATACG
TACATATGCTGTCCAAATATATTTGTATATATTTGTATAGCATTTTTACACCTTTATTGAGTAATCTGGTTTCGAAAGGAGGTGAGAGTT
TAGTCCCTTCTGCAGTTTTCTCCAAGCTGTGTCCTGTGAATTTCAACCCTTGGAGCCTAAGAAAACCCTAGGAAGATGATGTTAATTTGC
TGTCATTTCCTAATTCAGGATCTATCATCAAATGAAACATGAAAAAAACAGTGACTTTTAAGGTGAAAAGAGTTTCAAGCATTCCAAATA
AATTATCAATGTTTCATAACTTTTTATTATAAACCCACCTCCTAATAGGAAGCCAAGTACTATTTGATACAGTGGTAAAAACCAAACTAC
CTTGAATTTTTTTAAGGCAACTTATGAATAATGCTCATTTTCACAGTCAGAATAGCTTTAAAATATGGTTGAATTTGATACACACAGGAA
GTTTTCTTGAAGAACAATCCTTTCGCTTTTCTTTTTTCTTGAGAGATCTAAAGAGAAACTGTAGATTGTTTTCCTGACAGCAAAAGACTA

>In-frame_SECISBP2_ENST00000534113_chr9_91956394_+_NEDD4L_ENST00000356462_chr18_56063399_+_2024nt
ACCCAGCGCAGTGACTGCGGCCCAGCCCGGCGCTCCCCGCAGTCGGGGCGGGGGGACTCTGGCGAGCTTCCCGCGCTCTTGGGAACGGAT
AGATTGTTTTAAAGGATCCTGCGTTTTTCTGAACGTCATTCTCCGCTCTACGTACTCAGCATTACCACTAGATGGAGCCCTGGCGATCGC
TTGCATCATTTTTAGACCCATAAAATTCTCGGTGAAAGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCT
CAATGTGGCATGGTTAGAGTCCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGAC
AGAGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATA
TGCCTATTCTCCTTATACCCTTGACTCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCG
AGGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGA
GAAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCA
TTTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATC
TACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACC
CAAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAAT
AGTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAAT
GGGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTC
ATCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCC
TACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATC
AAAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGA
CAGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTT
GGACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTT
AATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGG
GTGGATTAAGCACCCTGTGCCTCGGGGGTGGTTGTTCTTCAAGCAAGTTCTGCTTGCACTTTTGCATTTGCCTAACAGACTTTTGCAGAG
GCGATGGCAGAGAGCAGCTGCAGGCATGGTCCCTGGAGCCGAGCCTTCACCACGCACTCGTCCAAGTTCGGATGCGGGAACCTGGTCCCA
GCTTGAGTTCCTGCCTTTCCCACCACAAATTATCAACTGGTTGATGTGTACACTAATTACATTTCAGGAGGACTTAATGCTATTTATGTT

>In-frame_SECISBP2_ENST00000534113_chr9_91956394_+_NEDD4L_ENST00000382850_chr18_56063399_+_6989nt
ACCCAGCGCAGTGACTGCGGCCCAGCCCGGCGCTCCCCGCAGTCGGGGCGGGGGGACTCTGGCGAGCTTCCCGCGCTCTTGGGAACGGAT
AGATTGTTTTAAAGGATCCTGCGTTTTTCTGAACGTCATTCTCCGCTCTACGTACTCAGCATTACCACTAGATGGAGCCCTGGCGATCGC
TTGCATCATTTTTAGACCCATAAAATTCTCGGTGAAAGGCATCAAGTTATCAGCAGATGTCAAACCATTTGTCCCCAGATTTGCCGGGCT
CAATGTGGCATGGTTAGAGTCCTCAGAAGCATGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGAC
AGAGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATTTATCTTCTGAGATAACTCTTCATCCATA
TGCCTATTCTCCTTATACCCTTGACTCCACACAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCG
AGGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAGCTCTGTTTAAGAAGAAAACCTATGATGA
GAAAAAAACGTATGATCAGCAAAAGTTTGACAGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCA
TTTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGAAATCCAGAATCATTGCAAAAAATGTATC
TACCTCCAAACCTGAGTTTGAATTTACCACACTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACC
CAAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAACCAGCTGCAGTGTTATCAAAGGGTGAAAT
AGTGGTGAAAAATAACCCAAATGAATCTGTAACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAAT
GGGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACTTCTATGATAAACTTAAAGACCATTGCTTC
ATCAGCAGATCCTAAAAATGTTAGTATACCATCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCC
TACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAGAATAAGAAAAAGAAAGAAAAATCTACATC
AAAATATGAAGTCCTGACAGTTCAAGAGCCTCCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGA
CAGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAATGTAAAGAAGAGCCAGCTTCCAGTGCAGTT
GGACTTGGGGGGCATGCTGACAGCCCTGGAGAAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGCTTT
AATCGCCTTGACTTACCTCCATATGAAACCTTTGAAGATTTACGAGAGAAACTTCTCATGGCCGTGGAAAATGCTCAAGGATTTGAAGGG
GTGGATTAAGCACCCTGTGCCTCGGGGGTGGTTGTTCTTCAAGCAAGTTCTGCTTGCACTTTTGCATTTGCCTAACAGACTTTTGCAGAG
GCGATGGCAGAGAGCAGCTGCAGGCATGGTCCCTGGAGCCGAGCCTTCACCACGCACTCGTCCAAGTTCGGATGCGGGAACCTGGTCCCA
GCTTGAGTTCCTGCCTTTCCCACCACAAATTATCAACTGGTTGATGTGTACACTAATTACATTTCAGGAGGACTTAATGCTATTTATGTT
GTGCCTCTGCAGGCAAAGCCCTTAATAAATATTTTACATCCTTTCTAATGACAATGAATGGAATTAATCACTCAACAGGTATAGTATTAC
GACTCATGTTTACTTTTTAAAATGATTTAGACCGATTTTCAGATTTTATTTCGTTATGATTAAAGATGTCTCATGTACTTGGAAAAGTGA
GCATTTTTTTTTTTTTTGTATTTCACTTTCATACCAGGCTTAATGTCAATGACATTTTTATTTTTGAAGTACTCTGACACCTCCACCCTC
TACTTTATTAGAATTGGAAGGCAAATTTTTGTCCAAAAACCTACAGACAAGTACTTTGAGAGAATTTCCAATATAATATTAGACATAATG
ATAATTTTTTCCATACTCAGAATGAAAAACTGGATATTACGTTTTTGTTTTGGGGTTTTTTTGTACAAATTTAGCTAATAGCTACAGGCT
GAGAGAATTGTAACATAGCATGACAAATTTTGTGTTGACTTGAAAGGAATCACACCATTATTCCTTAGAAGTAATTACATGTGTTCTAAC
ACATTTGAGACAGGGTTGGACTCCCATTTCTCATCCGAGAAATTACTTAACCCTTCCTGGCGCTGTACAGTCATCTTTTATTCTATTTCC
TCTTTGCTGTTTGTAGTAGAGACATTTTGAATGAAACTTGGCACTGCTTGATTCAAAACTGTGGAAACCAGATCTGTTTAGTCTCCTGTT
TGTATGCGTTTGCTAATGGTAGCTAAATAACCAGTTTTTGTTGTAAATGCACCAATTCTGAAGGCACTTTATGTACTACATGGAGGTCAT
ATCTGGTTTTGTTTTTATTTTTTTATCATGAACATTAAATGTGATGATGATTTCTTTTCCCTGCACACATCTTTCCGGTGCAATATCTAT
CAATTGTGAATCTGGCTGCTGGTGTATAAAAACCTGGATGTAAAGCTGAGCCTACAGACCTGTCCTCACCAACTGTTTTGTGATTTCTAC
TCAACTACAAAGATTTATTTAATGTACTCTTAATCTAACTGAGTTTTGTTACCAATGACCTGTTGCATGCTTCAATACCGTGTACTGCCT
GAGTTGTGCCTCTTGTGTGCTAGATTAAAAGTGAGACAGAGACTTGACTTGATCCTCTGAGCTCAAGCTATTGAGCTGGTAGTGGCAGAG
GACTGAGGGTACCTGCACAGTTTGATTCTTTTCCACGTGTAAGTCTCCATTGCAGAATTGTCGTGCTTTGAGAAAACACCTGAGGCAGTG
TGGGAGTTGAACGACCCTGCTGTCCTTTTTAACCTGTGTTGTCCTAGACCCTGTCGGGGCAGTCAGGGGACACTAGAGATTTGATCTCAT
GCGAGTCATCAATAGGACAAAAAAGTTGTGGTTTGGGGAGGTCTGTTTGTTACATAAAAAGGACCTTTCGGTGTAAGAAATTGCCGTTTT
TACCCTGCCCTGGCTGGCATGTGAGAAGCCATGGAAGGTTGTGGTTGTAAATGAGTTGTCTAAAGGGGTGCAGAGGCCTGAGGTTTCTAA
AAGAAGGTAGATTTCTACAGAGCTGAGTGTTGGTTCCTTTTTCTTATTGGTTGAAAATTACCTGGTAGTGATCAGAAAACTTAGATGCTA
TGTAACTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTCCCGCTCATGAGTTTTGACTATTGGTGAGATGTTTTCCGCTACA
GTTAACATGACAAATGTCTCAGTGGCAAAAATCCCCTTTTTGTAAGCCCCCATAGTCTAGAGGCAGTTTTCTTTTTAAGAATCATGCCAG
AGCCTGAGTCGAGCAGTATGCTTTCTTGGTTTTTGAGAGTAATTGTGTAATTGTAGAGGGAGAAATCCAATTCTAACCTAAGAACTGGGA
TTCTTCTGTCATCTTGTAAACCGTATATTGAAAAAAACAGAATGTCACTAAATGCATATTAAGTCAAGTATTGGAAAGTATAAAAGAAAA
ATCATTCTGACAATTTCTAAGCCAGAAGCAAACAAGAATTACTGAAATCTACCCCATGAATACTTGGAAGGCAGTAATTGTGAGTGACAC
CTCAGTTCATCAACCCCTTAATAATATCAGCTTAATTTTAATGACAACTAAATATGCTGAAGTGAGGATTTAGTATTTTTTAAAAAAGCA
AAACAAGGTTCAGTAGTCCTCAGCAATTCTCCAAGTTTCTCTCTTTGCCTAAAATGGTCATAGATCTTGATTTCTCTGAATCGTGATGAC
CACACCCAGTCATCTTCACAGCATAATTGCAGGTGGCAGTAAAGAGAGTGTGCTGGGTAAGGAGCAGTTGCTGGGTCATTCCTTGGGCCC
CGACCTGCCCGGGGAGTAGCCCTGGGGGAGAGAGGGCAGTGTTGCCTATCCCAGAGGTCCCAGCAGTCACACTGCTCTGCAGGCCGGGCT
CTCTTTATAGCCAGAGAAATCACCTTAATGCAGTCTCTTTAGTTGTCTGCTGAAGCTGTAGTTATTATGGGCCACTTACATGAGGCTGAG
AAGTACGTGCCGGAGCTCACACACTGCCTGTTGCGGTTCTCTTAACATCAGTTATCACAGCTGCCTGTGGGTCCCGGGTATTTCCATTCC
TGCCCCTTGTTGGCCCGAGGAAGGATGTGGAAAGAGCACCTGGTGGGATGAAGGTCCAACAGCCTGTGCCTCTCCACTGCTGGCCCTGGA
GCCGGCAGCAGTGAGGCATTCATTGTCTGTGTTGCGGTGTATTCCCAGCTTCAGTGCTCTTTTCCTTTTTGCCTGAAATGTTTATGCTTC
TCTGCAGCCAGTCCTCTAACAAATCTCAAGAACAAAGGTAAGACACTTGGTTTTTGTTTCCAGGACCCTTCAGAAGGTGACATCAGATAT
TCCCTAAATTCAGACAATGAGGGATACAGAGCGACTTGGCATGTATTATTTCTCCCATGTAAGGACAAAGGGACAGATTATTATTGTTAT
TTCTGAGACAGAGTCTTGCTCTGTAGCTCAGGCTGGAGTGCAGTGGCTCAATCTCAGCTCACCACAACCTCTGCCTCCTGGCTTCAAGCG
ATTCTTCTGCCTCAGCCTCCCCGAATAGTTGGGATTACAGGCACCCACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGATGGTT
TCACCATGCTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCTCCCGCCTCAGCCTTCCAAAGTGCTGGGATTACAAGCATGAG
CCACCGCACCCGGCCTCACAGTGACAGATTCTGAGAAACAGCATGCAAAACATTTGAACCATTTTCTACATCTCCCATTGTTGCATAGAG
AGTGTGCACCGCTGCTATCTTGCCAGATCCACACTGGTCCTCCCGAAAGCCAGGTTCATACACAGCAACTTTTTAATTATTCTAACAGTT
ACCCATTAACAGTCGACTCCTGTATTTCTGAGAGTCTTGTACTCACCTCTGAAATTTAAAAACGTATAAAGAGAGCCTGGGTTAATCAGT
TCTGCAGCCCCTACGTGACACTGTGCTAGTTCTCCTTCTTCTGTCTCCTCCTTACCCTGGCCCTGCACCCCTGTACTTAAGAGGGAGAGG
TGGGAGGTGCTGTCTGGTATCATTTGCTGCCTCGCCAGTAGAGGGTGCCGCTGTGCAGGGTAACTGCCCGCCTGCTCCCTTCCTGACCTC
CCCTGACCCCGAAGATCACTACCTCTGTCATTCAGGCATTGGGGTACATCCTGATAAGTCGTGTCAGAACTGCCAATTTCAGGACTGAGA
TGTGTTTTTAAAAAACAAATCCTTATAAACTCCACTTTGTACTTTAGATTTTAAAACTGGGGAAAAATGTGATATTCTTTGGACCACTTT
TTTAATTTATATAAGCCTTAATGAACAGTGTCTATACATTTGCATACACACACCCCCACCCCAGAGTGTTCTCAGTATGTCAGAGAAAGT
GCCACAGCATTAGGACGGGAGCTTGGAGAACGTTTTCTAGAAAAGGGTTAGCTTCCTGTTGGCATGAAATTTTCCAAGCAAACCTCATTA
AACATCTGTTGTTTGTTAAAGATGTTCCACTGAAAGCAACGCATGTTTCAAAGGCACGTCTTTCCGTTCGTTGGTTTTCTGTGTGTAAGG
AGTAGCATTGCTGTTGGCGCCTAACCTCGCGTGCACTGCATTCTCAACCCCGTACCAGTGCATCATCAGAAGCCTTCCTCGTGACCATAA
CTCTGTGTCTGCAGATATGTGTTCCCGTGTAAGCCAGTTTTCCCCTTTTACTCAGACTGATTTCACCTAGATTGTCACGGTTTCCTTCAT
GTTAACTTTGCGTGACTTTGTTCTTCCTTTACTACTCTGTATGTAATATATATACATATATACGTACATATGCTGTCCAAATATATTTGT
ATATATTTGTATAGCATTTTTACACCTTTATTGAGTAATCTGGTTTCGAAAGGAGGTGAGAGTTTAGTCCCTTCTGCAGTTTTCTCCAAG
CTGTGTCCTGTGAATTTCAACCCTTGGAGCCTAAGAAAACCCTAGGAAGATGATGTTAATTTGCTGTCATTTCCTAATTCAGGATCTATC
ATCAAATGAAACATGAAAAAAACAGTGACTTTTAAGGTGAAAAGAGTTTCAAGCATTCCAAATAAATTATCAATGTTTCATAACTTTTTA
TTATAAACCCACCTCCTAATAGGAAGCCAAGTACTATTTGATACAGTGGTAAAAACCAAACTACCTTGAATTTTTTTAAGGCAACTTATG
AATAATGCTCATTTTCACAGTCAGAATAGCTTTAAAATATGGTTGAATTTGATACACACAGGAAGTTTTCTTGAAGAACAATCCTTTCGC
TTTTCTTTTTTCTTGAGAGATCTAAAGAGAAACTGTAGATTGTTTTCCTGACAGCAAAAGACTAATGTGACAAAATGAAGTCATTGTAAA


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FusionGenePPI for SECISBP2_NEDD4L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SECISBP2ATXN7L3, APP, SMAD9, GOLGA2, PCM1, SPICE1, TRIM25NEDD4LSFN, NR3C1, ARHGDIA, SCNN1A, SCNN1B, SCNN1G, NEDD4L, AMOT, YWHAG, YWHAZ, PSMD4, YWHAB, TNK2, OCLN, APBB1, TOLLIP, NDFIP1, KCNB1, MAPKAPK3, CLIC2, EFEMP2, HGS, NDFIP2, MAP3K3, VDAC2, ZDHHC3, CAMK1D, RANBP10, CDK5, ABL1, MAGEB1, DMTN, AICDA, MARK2, KCNAB1, FKBP3, DAPK3, BRAF, MAP3K5, DDX54, ZAK, KCNAB3, NTRK1, CUEDC1, RPS6KB2, ABL2, CACNB1, YY1, MAP3K2, BBX, PRKX, ACVR1B, ADAP2, BMPR1A, AKT3, MINK1, AURKC, NSRP1, WIBG, SGK2, UBAC1, RPL30, MERTK, SRMS, SERPINF1, DYRK3, IFRD2, SCD, ROBO3, TRIM41, TMA16, TAF1B, SPAG8, STAC, H1F0, PRR16, KIFC3, RASL10B, PRRG1, CDK3, KCNAB2, FGF12, RNF7, APEX2, MRPL19, TGFB1I1, TBC1D7, NHP2, TMEM55A, CYP26B1, DECR2, SENP2, SIVA1, RASL11B, MAP2, STK40, NUDT16L1, C7orf50, TCEAL2, ZC3HAV1L, MOB3A, TARBP2, ZADH2, WBP2, ELAVL1, YWHAH, SGK1, RAF1, TSC22D3, WNK4, WNK1, IKBKB, SMAD7, AMOTL1, UBE2D2, UBC, SMAD2, SMAD3, YWHAQ, NPC2, MT2A, ATP1B1, CYBRD1, SLC7A7, PBX1, ACY3, HAX1, KIF3B, KCNH2, CAV3, UBE2L3, UBE2K, UBE2D1, UBE2E3, UBE2J2, CDC34, ARRDC3, ARRDC4, MED28, FBXL15, LAPTM5, RNF11, KCNQ1, SGK3, UBE2D3, NOTCH1, AATF, GORAB, UBE2N, HCN1, SMAD6, SLC9A3, SNCA, WNK3, PTCH1, DAZAP2, MOV10, CCDC8, FAM189B, PRRG3, TMEM51, TMEM171, SUSD6, FAM189A2, WBP1, ARRDC1, TMEM92, TMEM52B, LDLRAD4, XPO1, LITAF, SLC22A11, SLC22A8, RHOB, CRYAB, GRB10, KCNA3, ULK1, ERBB3, PTK2B, GRIA1, ILDR1, TNFAIP3, TNFRSF19, LPAR1, EDEM3, TRIM25, SCN5A, UBE2E1, UBE2E2, UBE2L6


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SECISBP2_NEDD4L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SECISBP2_NEDD4L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSECISBP2C0002514Amino Acid Metabolism, Inborn Errors1CTD_human
HgeneSECISBP2C0018273Growth Disorders1CTD_human
HgeneSECISBP2C1864761Thyroid Hormone Metabolism, Abnormal1CTD_human;ORPHANET;UNIPROT
TgeneNEDD4LC0020538Hypertensive disease2CTD_human
TgeneNEDD4LC0008925Cleft Palate1CTD_human
TgeneNEDD4LC0014175Endometriosis1CTD_human
TgeneNEDD4LC0039075Syndactyly1CTD_human
TgeneNEDD4LC1868720Periventricular Nodular Heterotopia1CTD_human;ORPHANET