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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 3304

FusionGeneSummary for ATP1A1_VANGL1

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP1A1_VANGL1
Fusion gene ID: 3304
HgeneTgene
Gene symbol

ATP1A1

VANGL1

Gene ID

480

81839

Gene nameATPase Na+/K+ transporting subunit alpha 4VANGL planar cell polarity protein 1
SynonymsATP1A1|ATP1AL2KITENIN|LPP2|STB2|STBM2
Cytomap

1q23.2

1p13.1

Type of geneprotein-codingprotein-coding
Descriptionsodium/potassium-transporting ATPase subunit alpha-4ATPase, Na+/K+ transporting, alpha 4 polypeptideATPase, Na+/K+ transporting, alpha polypeptide-like 2Na(+)/K(+) ATPase alpha-4 subunitNa+/K+ ATPase 4Na+/K+ ATPase, alpha-D polypeptideNa,K-ATPase suvang-like protein 1KAI1 C-terminal interacting tetraspaninloop-tail protein 2 homologstrabismus 2van Gogh-like protein 1vang-like 1 (van gogh, Drosophila)
Modification date2018052320180519
UniProtAcc

P05023

Q8TAA9

Ensembl transtripts involved in fusion geneENST00000295598, ENST00000537345, 
ENST00000369496, ENST00000491156, 
ENST00000355485, ENST00000369510, 
ENST00000310260, ENST00000369509, 
ENST00000474344, 
Fusion gene scores* DoF score15 X 20 X 7=21006 X 5 X 4=120
# samples 256
** MAII scorelog2(25/2100*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ATP1A1 [Title/Abstract] AND VANGL1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATP1A1

GO:0030317

flagellated sperm motility

12112599

HgeneATP1A1

GO:0030641

regulation of cellular pH

12112599


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBRCATCGA-E2-A15A-01AATP1A1chr1

116916145

+VANGL1chr1

116206282

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000295598ENST00000355485ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
In-frameENST00000295598ENST00000369510ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
In-frameENST00000295598ENST00000310260ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
In-frameENST00000295598ENST00000369509ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
5CDS-intronENST00000295598ENST00000474344ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000537345ENST00000355485ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000537345ENST00000369510ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000537345ENST00000310260ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000537345ENST00000369509ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-intronENST00000537345ENST00000474344ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000369496ENST00000355485ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000369496ENST00000369510ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000369496ENST00000310260ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000369496ENST00000369509ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-intronENST00000369496ENST00000474344ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000491156ENST00000355485ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000491156ENST00000369510ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000491156ENST00000310260ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-3CDSENST00000491156ENST00000369509ATP1A1chr1

116916145

+VANGL1chr1

116206282

+
intron-intronENST00000491156ENST00000474344ATP1A1chr1

116916145

+VANGL1chr1

116206282

+

Top

FusionProtFeatures for ATP1A1_VANGL1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP1A1

P05023

VANGL1

Q8TAA9


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28139_15168525Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28173_18268525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28204_22268525Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28244_52468525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28139_15168525Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28173_18268525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28204_22268525Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28244_52468525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17139_15168525Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17173_18268525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17204_22268525Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17244_52468525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28139_15166523Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28173_18266523Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28204_22266523Topological domainExtracellular
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28244_52466523Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28118_13868525TransmembraneHelical%3B Name%3D1
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28152_17268525TransmembraneHelical%3B Name%3D2
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28183_20368525TransmembraneHelical%3B Name%3D3
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+28223_24368525TransmembraneHelical%3B Name%3D4
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28118_13868525TransmembraneHelical%3B Name%3D1
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28152_17268525TransmembraneHelical%3B Name%3D2
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28183_20368525TransmembraneHelical%3B Name%3D3
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+28223_24368525TransmembraneHelical%3B Name%3D4
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17118_13868525TransmembraneHelical%3B Name%3D1
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17152_17268525TransmembraneHelical%3B Name%3D2
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17183_20368525TransmembraneHelical%3B Name%3D3
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+17223_24368525TransmembraneHelical%3B Name%3D4
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28118_13866523TransmembraneHelical%3B Name%3D1
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28152_17266523TransmembraneHelical%3B Name%3D2
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28183_20366523TransmembraneHelical%3B Name%3D3
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+28223_24366523TransmembraneHelical%3B Name%3D4

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+12382_8441024RegionPhosphoinositide-3 kinase binding
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+12382_84-89993RegionPhosphoinositide-3 kinase binding
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+12382_84-1211024RegionPhosphoinositide-3 kinase binding
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+1231007_102341024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123109_13141024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123153_28841024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123309_32041024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123339_77241024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+1236_8741024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123793_80241024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123824_84341024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123867_91841024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123939_95141024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123971_98541024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+1231007_1023-89993Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123109_131-89993Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123153_288-89993Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123309_320-89993Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123339_772-89993Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+1236_87-89993Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123793_802-89993Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123824_843-89993Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123867_918-89993Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123939_951-89993Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123971_985-89993Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+1231007_1023-1211024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123109_131-1211024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123153_288-1211024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123309_320-1211024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123339_772-1211024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+1236_87-1211024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123793_802-1211024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123824_843-1211024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123867_918-1211024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123939_951-1211024Topological domainCytoplasmic
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123971_985-1211024Topological domainExtracellular
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123132_15241024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123289_30841024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123321_33841024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123773_79241024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123803_82341024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123844_86641024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+12388_10841024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123919_93841024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123952_97041024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000295598+123986_100641024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123132_152-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123289_308-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123321_338-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123773_792-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123803_823-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123844_866-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+12388_108-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123919_938-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123952_970-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000369496+123986_1006-89993TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123132_152-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123289_308-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123321_338-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123773_792-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123803_823-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123844_866-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+12388_108-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123919_938-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123952_970-1211024TransmembraneHelical
HgeneATP1A1chr1:116916145chr1:116206282ENST00000537345+123986_1006-1211024TransmembraneHelical
TgeneVANGL1chr1:116916145chr1:116206282ENST00000310260+281_11768525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000355485+281_11768525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369509+171_11768525Topological domainCytoplasmic
TgeneVANGL1chr1:116916145chr1:116206282ENST00000369510+281_11766523Topological domainCytoplasmic


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FusionGeneSequence for ATP1A1_VANGL1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000355485_chr1_116206282_+_461aa
MGKGDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFI
SMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAIVLLELR
QLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAAR
RRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRITRQQNYHSMESIL
QHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIILSEEFIDPKSHKF

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000369510_chr1_116206282_+_461aa
MGKGDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFI
SMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAIVLLELR
QLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAAR
RRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRITRQQNYHSMESIL
QHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIILSEEFIDPKSHKF

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000310260_chr1_116206282_+_461aa
MGKGDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFI
SMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAIVLLELR
QLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAAR
RRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRITRQQNYHSMESIL
QHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIILSEEFIDPKSHKF

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000369509_chr1_116206282_+_461aa
MGKGDDNWGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFILLPPILWRDELEPCGTICEGLFI
SMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLVLIFLFVVSYWLFYGVRILDSRDRNYQGIVQYAVSLVDALLFIHYLAIVLLELR
QLQPMFTLQVVRSTDGESRFYSLGHLSIQRAALVVLENYYKDFTIYNPNLLTASKFRAAKHMAGLKVYNVDGPSNNATGQSRAMIAAAAR
RRDSSHNELYYEEAEHERRVKKRKARLVVAVEEAFIHIQRLQAEEQQKAPGEVMDPREAAQAIFPSMARALQKYLRITRQQNYHSMESIL
QHLAFCITNGMTPKAFLERYLSAGPTLQYDKDRWLSTQWRLVSDEAVTNGLRDGIVFVLKCLDFSLVVNVKKIPFIILSEEFIDPKSHKF


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000355485_chr1_116206282_+_1383nt
ATGGGGAAGGGGGATGACAACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGG
ATCAGCAAGGACATGGAGGACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTC
CTCACCCCTATTGCCTTCATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATC
TCCATGGCATTCAAACTCCTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTG
TTTCGTGCCCTTTTGTTGGTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGG
AATTACCAGGGCATTGTGCAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGG
CAGCTGCAGCCCATGTTCACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGA
GCAGCATTGGTGGTCCTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAG
CATATGGCCGGGCTGAAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGG
CGCAGGGACTCAAGCCACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCA
GTGGAAGAGGCCTTCATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCC
CAGGCCATTTTCCCCTCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTG
CAGCACCTGGCCTTCTGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGAC
AAGGACCGCTGGCTCTCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAG
TGCTTGGACTTCAGCCTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTT

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000369510_chr1_116206282_+_1383nt
ATGGGGAAGGGGGATGACAACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGG
ATCAGCAAGGACATGGAGGACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTC
CTCACCCCTATTGCCTTCATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATC
TCCATGGCATTCAAACTCCTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTG
TTTCGTGCCCTTTTGTTGGTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGG
AATTACCAGGGCATTGTGCAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGG
CAGCTGCAGCCCATGTTCACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGA
GCAGCATTGGTGGTCCTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAG
CATATGGCCGGGCTGAAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGG
CGCAGGGACTCAAGCCACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCA
GTGGAAGAGGCCTTCATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCC
CAGGCCATTTTCCCCTCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTG
CAGCACCTGGCCTTCTGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGAC
AAGGACCGCTGGCTCTCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAG
TGCTTGGACTTCAGCCTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTT

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000310260_chr1_116206282_+_1383nt
ATGGGGAAGGGGGATGACAACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGG
ATCAGCAAGGACATGGAGGACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTC
CTCACCCCTATTGCCTTCATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATC
TCCATGGCATTCAAACTCCTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTG
TTTCGTGCCCTTTTGTTGGTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGG
AATTACCAGGGCATTGTGCAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGG
CAGCTGCAGCCCATGTTCACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGA
GCAGCATTGGTGGTCCTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAG
CATATGGCCGGGCTGAAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGG
CGCAGGGACTCAAGCCACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCA
GTGGAAGAGGCCTTCATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCC
CAGGCCATTTTCCCCTCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTG
CAGCACCTGGCCTTCTGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGAC
AAGGACCGCTGGCTCTCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAG
TGCTTGGACTTCAGCCTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTT

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000369509_chr1_116206282_+_1383nt
ATGGGGAAGGGGGATGACAACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGG
ATCAGCAAGGACATGGAGGACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTC
CTCACCCCTATTGCCTTCATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATC
TCCATGGCATTCAAACTCCTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTG
TTTCGTGCCCTTTTGTTGGTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGG
AATTACCAGGGCATTGTGCAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGG
CAGCTGCAGCCCATGTTCACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGA
GCAGCATTGGTGGTCCTAGAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAG
CATATGGCCGGGCTGAAAGTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGG
CGCAGGGACTCAAGCCACAACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCA
GTGGAAGAGGCCTTCATCCACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCC
CAGGCCATTTTCCCCTCCATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTG
CAGCACCTGGCCTTCTGCATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGAC
AAGGACCGCTGGCTCTCTACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAG
TGCTTGGACTTCAGCCTCGTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTT


* Fusion transcript sequences (Full-length transcript).
>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000355485_chr1_116206282_+_8480nt
CTGGGGCGCAGAGCAGCGGCGGGAGGAGGCGGACACGTGGCAACAGCGGTAGCAGCCCGGGCGGCGGCAGCAACAGCGGCGGCGGCATCG
GCCCGAGCCGCCGGCCGCCCTCCCACCCTCCCGCCCCGCGGCAGCCCTAGCTCCCTCCACTTGGCTCCCCTGGTCCCGCTCGCTCGGCCG
GGAGCTGCTCTGTGCTTTTCTCTCTGATTCTCCAGCGACAGGACCCGGCGCCGGGCACTGAGCACCGCCACCATGGGGAAGGGGGATGAC
AACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGGATCAGCAAGGACATGGAG
GACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTCCTCACCCCTATTGCCTTC
ATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATCTCCATGGCATTCAAACTC
CTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTGTTTCGTGCCCTTTTGTTG
GTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGGAATTACCAGGGCATTGTG
CAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGGCAGCTGCAGCCCATGTTC
ACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGAGCAGCATTGGTGGTCCTA
GAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAA
GTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCAC
AACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATC
CACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCC
ATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGC
ATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCT
ACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTC
GTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCT
GAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGGGTG
TCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAGGAA
GCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTTCTG
TTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCCCCG
TTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGTATT
TGTGTATGTTAATGTCCAGTATCACATCACCCATGAAAGTCGTGGGCAGTTCAGGAGATACCTGCCTTCATCTTTGTTCTTTGTTGCCTT
AGGTTCTTCAGAGAAAGATCACAACAAAAAATGTACACTGTCGTTTACAGCTATTAAGTGATTTGATTTTGTTTTTTTCCCAAAGAGAAA
ACCTACCTGCCCTGTTTCTGATCCCACCCCTCTGCTGGCTTGAAGCAGGTAACCCTTTCCCAGCCCTGCAGCTGCCCACCTGGCCTCCAT
GCCATCCTGCCCCCACCTGGCTGGCAGCCCTGGCTCTCCATGTGTGCCCTCCGGCTCTGTGTGAAGCCTCAAGTCAGTCCCAGCATTGTT
TCCATAGGGAAGTGTGGGGTGCCCAGCAGGTAAAGCACAGGGAGAGAGGGCAGTGGGAATGCCACCTTTAGGCTGCAGCAGGAGCCCCAC
ACTGCCCAGTTTTCCTCCCCACTGTTCTACACCAACCAGGGGAGACTAACACTGTGACTCTGGGATTGGCAGGTGCAACTTGGAGCCACT
TAATTTCCTGGGGACGTAAGTTCTTCCCAAGCTTAGAGCAAGCTGCCCTGCCAAAGGAGACCAAACCATGCCAACCACGCTGGCAACTGC
TGCTGTCCAGTCCCTGTGTTTTCTGACCACCGTCACTGTGCAACTCATCGCCTCTGCCACTTAGGACCAGGAAAGAGGCTGGTTTTGCTC
CCACTCTTAGTTGCTGATAAAGTGGGGAGAAGGAAAATGGACACTCTACAGAGTTTGGGGAAGGGAGAGTAGGGAGCCCATCTTGTCCAG
AAAGATTCATCTGTGGTCTGTCTGTTAAACACAGCTGATTTCAGTGGGCTTTCCCCTGGCCCTGGGGGAGCAGACACTGACTGGGTTGTG
GGCAGAGGAGCCATCCTGGCGGAGCCCTGCTGCAGGGGAGCTCCTTCAGGAGCCCCATCCGGACCTCTTGCACTGGGCTGCCTTTGCCTC
CATTTGCCTTCCTGTATCTGCAACAAACCTTTTAAAAGTGTTCACTCTTGCTTTTTCCAGTATTTCGGTAATCAGCCATCTTGCTGTAGT
ACAGGATGACATTGTCGAATGCTCTTTGTATGTGTGCACACCCCCTTACTCCCTTACTGCTTCATACACTCCACAAGTGGTACAGTATTT
TGTGTCATTGTAAAAATCAAAATTGGCTTTGGATCTTTGTAATACACCTGTACCTGAAAAAGTAAACAACATTCTTCAATTACTAGCCTT
CAGCTTGAAAAGACATGCTGGAGAAGAAGGAAGGGGGAACCCATAGGTGTGGCGTGGAGCCAAGATGTACTATTCAACTATGTGTTTCTG
TTTATAAAAAACACATACCATGGAACCATGGTGCTTTTGTTCTTAGTTTTTGCCGTTAGATCCCTTCAAACTGGAAGTTCCTTACAATAT
CTTTCTCAGGAAATATTTTGGGAAATGGGGTAAGAGATGGCAAGTGTGAGACGGGCTGTGTCAGAGGTTGCTACGTCATGGATACAGTGC
AGTTCCAAGTGCCATAAGTGTATGTACATATAGTTAATAATGACACTGTTCATCACCATTCTAAAATACTGTTCTTCCAACCCTATCTTC
AATGACCAGTCCAGAAGGGGTTAAGCTGGATTCATTTGCTCTGGCATGTGCATTCCCAGCAGGGTGAAGAAAGGTTTAAATTAAAGAATT
TATTTTCTCTCTCCCCCTTCCTCTTTCTCCCAGTCTTTGCATAGGAGAATGTTAGACATTCAGAAATTACTGTTTCTGTTTTAAATTGAG
TATTGATTTTTTTATATTGACTTTGTATTGAGTTCTTTTTGAAAGAATAACAAAATAAAATGCAGGATCTTTGTAAAGCCTTTGCACTTT
CAACCTCTTTATAGCTTGAGTTACTTTTGCAGTGGGAACAATGTAAATGACATTTAAAAGATTTAAGGTTTCAGAAAGCTGCATCCCACA
ATTGAACACAATGCATTTTTATTTCAATTCTTGGAACTGGTAGGCTATTCTTTTTAAAAGGGGGTAAACTTCGCCCTAAGGCTGGTAGAA
TGTATGTTCACATTATAGTAGACAGGATTTCATTTGCCTTATATGTTTATAGATTTTTTATAATTTTCATCCTACGTTATTAAAATTAGA
GCATTGAGTGTTAAAGAACTTAATGAGGAGTCTATATCTGAGATTGCTCTCTTCCCTGGTGATGTTTTAACTGGTAGATAATTTGTTCTT
AAATATGTACTTTTGAAGATAGGACAGTTTTTATAGTCCATGAACTGAATGTTAAAAAGTTCTGTATGCATTCTCAGAGAGGATTTTAAA
GCTATATAGTTCATCCATCCTTTGCATTATCAAAATGTTAAGTCAAATCTGTAATACTTTGGCTAAAATTCATAAAGTAAGCCCTAGAGA
AAATACTTGACCACCAAATTTTTGCCCAACTATCATCACCTCCCTTCCCCCGCCTCTGTTCTTGCCTTTTGACATCTACATGGAAGACAA
GTTCTTTACAGCAAATGGTAAGAGGCAGGTGACCTGGTGTGTTTGCTGTGTTGTAGTTCATTGCCTGGGGCTTGGGACTCCTTTTTTAAT
GGAGAGACTAGCTGTGCAGGTGTGTGTTGGATAGGGATAAAGTGCTCACCCCTGCCCTCTCTACAGTAGTTGGTGGTAGATTTCTCTCTC
ATTTTGCCTCATAATCACTTTCGAGTGCATGTATTTACCTAAGGGCTGTAGCTCTGTGGGATGCTACCAGCATATTGGACTGACAGAAAT
TGATTACCTTGCCACTCCAACCTACGTACTGAGTGAGTGCTCCAGCCACTCAGTGAAACCAACAAAAGTGAGTCCTTGGTTTACCTTCCA
ATCTGGGTCCTGCTGTGTAAGTATCCCTAAGTGGGGATGCATATTTGTTTGTGCGTTTTTATTTCCATATATGTGAGCATTTCTCTGAGT
GTATTACCAGACGGATAGCACATTTATATGTCAGACATCTTAACATCTGTGTTATCTGTAGCAGGTGTGTAGCTCAGCAGATACGTGTCA
TTGTGTATATAGCTGAGTGTGTGAGGGTGTCTGTGTTTCTGCAGTCCCCTGTGTTTGAGAGATGACTTAATAACCCTGTGTTTTGAGAGG
TCGCTCTAAACCAGTGACTTTTCCCTCCCCTGCTTTATTCCTTTCCCTCACTGACACTGGCTTCTCCCGCTAGAGTAAATGGCTTTAGCA
CAGCACTGTCTTCTGGGGAGCCTGCTGTCCTGCAGGCAAGTCCATTAAACTCTTTCTTGCTTTAGGACTCTGAAAACAGCAAGAAACAAA
CAAACAAAGGTCAAGCTCTAAGAAAATTACTGCTCAAACTTCACTACCCTGGAAGCCTTACTAGATATTTCTTAAGGTAACTTAAAAATT
GGGCTTTATTTTTAAAAAGTGATAGGTTACTTACAGTAGCACAGAAATGTTAGCATATTTATTTAAATAGTCCTGCAGCAGAGACCCTGC
GATTGTAAAGTGATTTAAGTATTTCTGGGTAGTGTTTGTGATTTACGGATTTGTTACTGAAAAACAAAAAAATCACTACTGTGAATTTAC
TACTATGTAACCTTGTGGTCGTATTTCATTATAAATAAAATAAGAATTGCTCTTCTGCCCACCGTTCTTGATTGGTATTCAGTGCAGTAG
CGAAATGAGATAGTTTAGACACTGTTGAAATAACTGCATTGAGCTTTAACCAAGTGTATGCTCAGAAAATTCAGTTTTGGATCACATTTT
GACAAAACATGTTTTGGTCAAAGAAAGGAAAGGCTACTAACACATTTATCAGGTAATGTATGTCACAGTCCGTGTTCCACCCAGCCTTGT
TATCCCCACATTCTTTCAAGATAGGAGTCATCTTGGTTTTTCGGGTGAAAAACGGAAGGTCAGAGAGGAAGGGGCTTGTCCAAGGTCTCA
TGTCTGGTTAACAGAATTTCAAACTAGATGTTTGATTCTAACCCCTCAGTCCACTGTACCTTGAAGTATGGTCTAAATGATTCGGCACTT
CTGGATGTTGAGGAAGGACCTAGAGACACATCCTTGAACTAGAACCTGGGGTGAGAGTTCATTGGGAGGCAGGATCTCTTCTTTCACTTT
GGATTTACACCTTGTCCCTTGGAAAGCTTCTCCACTATGCTAGCAAATATCTTAGGATATTTGATGGAAAGAACTTGAGAATCCCTTCTG
GAAAACCCAGCCTTTCAGTGTTAACACCTGCTGCAAGACAGGGATGCTGTTGTTCTGGCAGCCCCCCTTTGCTTTTGCCTGGCCCCACCT
TCTGCTCCCACTCTGCTGGCTTGGGCAAGATGCGTGCCTTGGGCCTTGGGTGCAGGGAGGCAGGCAGGGGCTTGACCTGGCCTCTCTCTG
GTGCCATGGCAACATTATGCCCCAAACTTCTTCCCTGGTTGGAGTGAGAGGGGCTGTCCACAGCCCCATCCTGTGGGGATCTCAAGCCGG
AGTCCCTGGCCTGGCCTCCTTGACGTAGGTGTTCTCAGCAAGCAGTTTGCATCCCACCGTCTTTCTCACACTTGCCCCCAAGACTTTTGA
CAGAGCAGACGTAAAACAGGACTCAGAAAACCATTTTTCTCTGTTCCCATATGTAGTAAGTTTTGATTCAGTTGTGCATAAACCATAGTT
TTCTGCCCTGCTGTTTGCTTTCAATGGAAGACAGTAAAGGGAAGATGGTGCTCACATCTCTCCATGTGACATCTCATTAGGAATTAAGAT
GCGATGGATTAGAAATGTAAAACTTCAGAATAAAATTAAATTTCAGGGCTCTATAAGTCCCGTTTTCCCAGGTCCTGTTCCGTTTCTACG
TAGATAACCCAATTTGTTTTGTCTATGAAATAAGCCTCTTTAGTGGGTTGTTTTAGTCTCTCCAACAAAAGAGCAGATTCCTAAAGCCAG
GTGCAGCACTGTGAAAAGTTTCTTTCAATATGGCACCAAGACTCTACCATTTATGTCTCTCTCAGCTTACAAACATCAGCGTTTTGTCCT
TGTCATAGTGGAAGAAAGACACTTACTTTAAGCTTTGGGGACAAAGGTGACAAACCCCAGGCTTTTATCTTAAAAGTGTCTTTGGCACTT
CTTTTGGCACTGAAATGGTATTTGGGAAGCATTATTTGAATGTACAGTTGTTTGGTTTTGTATGTGCTTATCTTTATCTGAGCTTTCACT
TGTAGACATGGCCTTTTGTTGTGAAGTTGCTCATCATTTAGGAGTGTTTAATTCTAAAAAGCCTTCAGCCTAAGAAAGCTTCATCTGTGG
GGACCAGAGACTTGTTGCTCAGGGAGTTAGTGATGGGACTTGGGCATCTGATCTGCAGGTGACAAGTTTAGTTCAACTGAAGTTGTAGGG
AATTTAGACAGTTGCACATCATTGCCGTTCTAGGGGCCTTGTAGAAAGATGAAACAGTTGTTTTTCATTTACCAGCACCTCTCAGTTATA
GAGGTAATGGAACATTCGCTTACTTTTCATCATCATTCTTTAAAAAGGGAACATACAAAAATCTAAACTATGGCAATAATTTATTTTTAT
AATAGTTTACGGTAGGCTTTAATTAAATGGCAAACTCCTCTGGGACCCCTAAGTTATGGCGTGATTAGCCAAATTTGATTTCCAACAGTC
ATTTATGGCCATAACTATTGCATAGAGTGCAGGATGCCAGCAAAGATGAGGGTGGGGGCAGATACTGGCTCAGTGATTTAACTCACATTA
TAGATGACCCCTTCCTCAACAGAAATGCTACTGAGAGAACCAGAGAGGCCTGGGCCAGGCAGGTCTTATTTGAGAGGAGATTATTTGATA
ATTGCTTTGGTTAGAAGGACTTTACATTTCCTGATTTCAAGTCCAGCACCAATTTAGAAAGTTCAGAGATGAAACCACCTGTCTTTACCT
GACAGAGTCATAACGGTTTGTGTAAAAATGTGGTCAGGGACCTTTTTTGTTCTTTCTGATTAGTTAATACTGTACATTGTAACCAGGAGG
GGCAGTTTTGCCAACCAGCCTCTGCTCATGGTCACCATATGTGTATGACAAGGCCTGAGTGAGTTCCTGCATAAACTGGGTAGTGGGCTC
TTTTGACACATTTGCAAGCATGTAAATGAATGAATGACACTACCAGCAACCATCTGTACAGGTCCATTTACTTACATTCATAAGGTTTAT
GCTATGAAACTTCTTCTCATTGTGATGTCAGTAACAGAGTTAGTGTCTCTGATGGAATAGTGTACCTGTCACCCAAGTTATTTTGTTCCT
TTTTGGGTCCTCCAGTATAATCCCCCCCTCATCCCAATTAACTGTAAAATGTTTTACACATCACATTTTTTATACTGTAAACTTGGAAAA

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000369510_chr1_116206282_+_8480nt
CTGGGGCGCAGAGCAGCGGCGGGAGGAGGCGGACACGTGGCAACAGCGGTAGCAGCCCGGGCGGCGGCAGCAACAGCGGCGGCGGCATCG
GCCCGAGCCGCCGGCCGCCCTCCCACCCTCCCGCCCCGCGGCAGCCCTAGCTCCCTCCACTTGGCTCCCCTGGTCCCGCTCGCTCGGCCG
GGAGCTGCTCTGTGCTTTTCTCTCTGATTCTCCAGCGACAGGACCCGGCGCCGGGCACTGAGCACCGCCACCATGGGGAAGGGGGATGAC
AACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGGATCAGCAAGGACATGGAG
GACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTCCTCACCCCTATTGCCTTC
ATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATCTCCATGGCATTCAAACTC
CTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTGTTTCGTGCCCTTTTGTTG
GTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGGAATTACCAGGGCATTGTG
CAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGGCAGCTGCAGCCCATGTTC
ACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGAGCAGCATTGGTGGTCCTA
GAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAA
GTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCAC
AACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATC
CACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCC
ATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGC
ATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCT
ACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTC
GTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCT
GAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGGGTG
TCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAGGAA
GCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTTCTG
TTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCCCCG
TTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGTATT
TGTGTATGTTAATGTCCAGTATCACATCACCCATGAAAGTCGTGGGCAGTTCAGGAGATACCTGCCTTCATCTTTGTTCTTTGTTGCCTT
AGGTTCTTCAGAGAAAGATCACAACAAAAAATGTACACTGTCGTTTACAGCTATTAAGTGATTTGATTTTGTTTTTTTCCCAAAGAGAAA
ACCTACCTGCCCTGTTTCTGATCCCACCCCTCTGCTGGCTTGAAGCAGGTAACCCTTTCCCAGCCCTGCAGCTGCCCACCTGGCCTCCAT
GCCATCCTGCCCCCACCTGGCTGGCAGCCCTGGCTCTCCATGTGTGCCCTCCGGCTCTGTGTGAAGCCTCAAGTCAGTCCCAGCATTGTT
TCCATAGGGAAGTGTGGGGTGCCCAGCAGGTAAAGCACAGGGAGAGAGGGCAGTGGGAATGCCACCTTTAGGCTGCAGCAGGAGCCCCAC
ACTGCCCAGTTTTCCTCCCCACTGTTCTACACCAACCAGGGGAGACTAACACTGTGACTCTGGGATTGGCAGGTGCAACTTGGAGCCACT
TAATTTCCTGGGGACGTAAGTTCTTCCCAAGCTTAGAGCAAGCTGCCCTGCCAAAGGAGACCAAACCATGCCAACCACGCTGGCAACTGC
TGCTGTCCAGTCCCTGTGTTTTCTGACCACCGTCACTGTGCAACTCATCGCCTCTGCCACTTAGGACCAGGAAAGAGGCTGGTTTTGCTC
CCACTCTTAGTTGCTGATAAAGTGGGGAGAAGGAAAATGGACACTCTACAGAGTTTGGGGAAGGGAGAGTAGGGAGCCCATCTTGTCCAG
AAAGATTCATCTGTGGTCTGTCTGTTAAACACAGCTGATTTCAGTGGGCTTTCCCCTGGCCCTGGGGGAGCAGACACTGACTGGGTTGTG
GGCAGAGGAGCCATCCTGGCGGAGCCCTGCTGCAGGGGAGCTCCTTCAGGAGCCCCATCCGGACCTCTTGCACTGGGCTGCCTTTGCCTC
CATTTGCCTTCCTGTATCTGCAACAAACCTTTTAAAAGTGTTCACTCTTGCTTTTTCCAGTATTTCGGTAATCAGCCATCTTGCTGTAGT
ACAGGATGACATTGTCGAATGCTCTTTGTATGTGTGCACACCCCCTTACTCCCTTACTGCTTCATACACTCCACAAGTGGTACAGTATTT
TGTGTCATTGTAAAAATCAAAATTGGCTTTGGATCTTTGTAATACACCTGTACCTGAAAAAGTAAACAACATTCTTCAATTACTAGCCTT
CAGCTTGAAAAGACATGCTGGAGAAGAAGGAAGGGGGAACCCATAGGTGTGGCGTGGAGCCAAGATGTACTATTCAACTATGTGTTTCTG
TTTATAAAAAACACATACCATGGAACCATGGTGCTTTTGTTCTTAGTTTTTGCCGTTAGATCCCTTCAAACTGGAAGTTCCTTACAATAT
CTTTCTCAGGAAATATTTTGGGAAATGGGGTAAGAGATGGCAAGTGTGAGACGGGCTGTGTCAGAGGTTGCTACGTCATGGATACAGTGC
AGTTCCAAGTGCCATAAGTGTATGTACATATAGTTAATAATGACACTGTTCATCACCATTCTAAAATACTGTTCTTCCAACCCTATCTTC
AATGACCAGTCCAGAAGGGGTTAAGCTGGATTCATTTGCTCTGGCATGTGCATTCCCAGCAGGGTGAAGAAAGGTTTAAATTAAAGAATT
TATTTTCTCTCTCCCCCTTCCTCTTTCTCCCAGTCTTTGCATAGGAGAATGTTAGACATTCAGAAATTACTGTTTCTGTTTTAAATTGAG
TATTGATTTTTTTATATTGACTTTGTATTGAGTTCTTTTTGAAAGAATAACAAAATAAAATGCAGGATCTTTGTAAAGCCTTTGCACTTT
CAACCTCTTTATAGCTTGAGTTACTTTTGCAGTGGGAACAATGTAAATGACATTTAAAAGATTTAAGGTTTCAGAAAGCTGCATCCCACA
ATTGAACACAATGCATTTTTATTTCAATTCTTGGAACTGGTAGGCTATTCTTTTTAAAAGGGGGTAAACTTCGCCCTAAGGCTGGTAGAA
TGTATGTTCACATTATAGTAGACAGGATTTCATTTGCCTTATATGTTTATAGATTTTTTATAATTTTCATCCTACGTTATTAAAATTAGA
GCATTGAGTGTTAAAGAACTTAATGAGGAGTCTATATCTGAGATTGCTCTCTTCCCTGGTGATGTTTTAACTGGTAGATAATTTGTTCTT
AAATATGTACTTTTGAAGATAGGACAGTTTTTATAGTCCATGAACTGAATGTTAAAAAGTTCTGTATGCATTCTCAGAGAGGATTTTAAA
GCTATATAGTTCATCCATCCTTTGCATTATCAAAATGTTAAGTCAAATCTGTAATACTTTGGCTAAAATTCATAAAGTAAGCCCTAGAGA
AAATACTTGACCACCAAATTTTTGCCCAACTATCATCACCTCCCTTCCCCCGCCTCTGTTCTTGCCTTTTGACATCTACATGGAAGACAA
GTTCTTTACAGCAAATGGTAAGAGGCAGGTGACCTGGTGTGTTTGCTGTGTTGTAGTTCATTGCCTGGGGCTTGGGACTCCTTTTTTAAT
GGAGAGACTAGCTGTGCAGGTGTGTGTTGGATAGGGATAAAGTGCTCACCCCTGCCCTCTCTACAGTAGTTGGTGGTAGATTTCTCTCTC
ATTTTGCCTCATAATCACTTTCGAGTGCATGTATTTACCTAAGGGCTGTAGCTCTGTGGGATGCTACCAGCATATTGGACTGACAGAAAT
TGATTACCTTGCCACTCCAACCTACGTACTGAGTGAGTGCTCCAGCCACTCAGTGAAACCAACAAAAGTGAGTCCTTGGTTTACCTTCCA
ATCTGGGTCCTGCTGTGTAAGTATCCCTAAGTGGGGATGCATATTTGTTTGTGCGTTTTTATTTCCATATATGTGAGCATTTCTCTGAGT
GTATTACCAGACGGATAGCACATTTATATGTCAGACATCTTAACATCTGTGTTATCTGTAGCAGGTGTGTAGCTCAGCAGATACGTGTCA
TTGTGTATATAGCTGAGTGTGTGAGGGTGTCTGTGTTTCTGCAGTCCCCTGTGTTTGAGAGATGACTTAATAACCCTGTGTTTTGAGAGG
TCGCTCTAAACCAGTGACTTTTCCCTCCCCTGCTTTATTCCTTTCCCTCACTGACACTGGCTTCTCCCGCTAGAGTAAATGGCTTTAGCA
CAGCACTGTCTTCTGGGGAGCCTGCTGTCCTGCAGGCAAGTCCATTAAACTCTTTCTTGCTTTAGGACTCTGAAAACAGCAAGAAACAAA
CAAACAAAGGTCAAGCTCTAAGAAAATTACTGCTCAAACTTCACTACCCTGGAAGCCTTACTAGATATTTCTTAAGGTAACTTAAAAATT
GGGCTTTATTTTTAAAAAGTGATAGGTTACTTACAGTAGCACAGAAATGTTAGCATATTTATTTAAATAGTCCTGCAGCAGAGACCCTGC
GATTGTAAAGTGATTTAAGTATTTCTGGGTAGTGTTTGTGATTTACGGATTTGTTACTGAAAAACAAAAAAATCACTACTGTGAATTTAC
TACTATGTAACCTTGTGGTCGTATTTCATTATAAATAAAATAAGAATTGCTCTTCTGCCCACCGTTCTTGATTGGTATTCAGTGCAGTAG
CGAAATGAGATAGTTTAGACACTGTTGAAATAACTGCATTGAGCTTTAACCAAGTGTATGCTCAGAAAATTCAGTTTTGGATCACATTTT
GACAAAACATGTTTTGGTCAAAGAAAGGAAAGGCTACTAACACATTTATCAGGTAATGTATGTCACAGTCCGTGTTCCACCCAGCCTTGT
TATCCCCACATTCTTTCAAGATAGGAGTCATCTTGGTTTTTCGGGTGAAAAACGGAAGGTCAGAGAGGAAGGGGCTTGTCCAAGGTCTCA
TGTCTGGTTAACAGAATTTCAAACTAGATGTTTGATTCTAACCCCTCAGTCCACTGTACCTTGAAGTATGGTCTAAATGATTCGGCACTT
CTGGATGTTGAGGAAGGACCTAGAGACACATCCTTGAACTAGAACCTGGGGTGAGAGTTCATTGGGAGGCAGGATCTCTTCTTTCACTTT
GGATTTACACCTTGTCCCTTGGAAAGCTTCTCCACTATGCTAGCAAATATCTTAGGATATTTGATGGAAAGAACTTGAGAATCCCTTCTG
GAAAACCCAGCCTTTCAGTGTTAACACCTGCTGCAAGACAGGGATGCTGTTGTTCTGGCAGCCCCCCTTTGCTTTTGCCTGGCCCCACCT
TCTGCTCCCACTCTGCTGGCTTGGGCAAGATGCGTGCCTTGGGCCTTGGGTGCAGGGAGGCAGGCAGGGGCTTGACCTGGCCTCTCTCTG
GTGCCATGGCAACATTATGCCCCAAACTTCTTCCCTGGTTGGAGTGAGAGGGGCTGTCCACAGCCCCATCCTGTGGGGATCTCAAGCCGG
AGTCCCTGGCCTGGCCTCCTTGACGTAGGTGTTCTCAGCAAGCAGTTTGCATCCCACCGTCTTTCTCACACTTGCCCCCAAGACTTTTGA
CAGAGCAGACGTAAAACAGGACTCAGAAAACCATTTTTCTCTGTTCCCATATGTAGTAAGTTTTGATTCAGTTGTGCATAAACCATAGTT
TTCTGCCCTGCTGTTTGCTTTCAATGGAAGACAGTAAAGGGAAGATGGTGCTCACATCTCTCCATGTGACATCTCATTAGGAATTAAGAT
GCGATGGATTAGAAATGTAAAACTTCAGAATAAAATTAAATTTCAGGGCTCTATAAGTCCCGTTTTCCCAGGTCCTGTTCCGTTTCTACG
TAGATAACCCAATTTGTTTTGTCTATGAAATAAGCCTCTTTAGTGGGTTGTTTTAGTCTCTCCAACAAAAGAGCAGATTCCTAAAGCCAG
GTGCAGCACTGTGAAAAGTTTCTTTCAATATGGCACCAAGACTCTACCATTTATGTCTCTCTCAGCTTACAAACATCAGCGTTTTGTCCT
TGTCATAGTGGAAGAAAGACACTTACTTTAAGCTTTGGGGACAAAGGTGACAAACCCCAGGCTTTTATCTTAAAAGTGTCTTTGGCACTT
CTTTTGGCACTGAAATGGTATTTGGGAAGCATTATTTGAATGTACAGTTGTTTGGTTTTGTATGTGCTTATCTTTATCTGAGCTTTCACT
TGTAGACATGGCCTTTTGTTGTGAAGTTGCTCATCATTTAGGAGTGTTTAATTCTAAAAAGCCTTCAGCCTAAGAAAGCTTCATCTGTGG
GGACCAGAGACTTGTTGCTCAGGGAGTTAGTGATGGGACTTGGGCATCTGATCTGCAGGTGACAAGTTTAGTTCAACTGAAGTTGTAGGG
AATTTAGACAGTTGCACATCATTGCCGTTCTAGGGGCCTTGTAGAAAGATGAAACAGTTGTTTTTCATTTACCAGCACCTCTCAGTTATA
GAGGTAATGGAACATTCGCTTACTTTTCATCATCATTCTTTAAAAAGGGAACATACAAAAATCTAAACTATGGCAATAATTTATTTTTAT
AATAGTTTACGGTAGGCTTTAATTAAATGGCAAACTCCTCTGGGACCCCTAAGTTATGGCGTGATTAGCCAAATTTGATTTCCAACAGTC
ATTTATGGCCATAACTATTGCATAGAGTGCAGGATGCCAGCAAAGATGAGGGTGGGGGCAGATACTGGCTCAGTGATTTAACTCACATTA
TAGATGACCCCTTCCTCAACAGAAATGCTACTGAGAGAACCAGAGAGGCCTGGGCCAGGCAGGTCTTATTTGAGAGGAGATTATTTGATA
ATTGCTTTGGTTAGAAGGACTTTACATTTCCTGATTTCAAGTCCAGCACCAATTTAGAAAGTTCAGAGATGAAACCACCTGTCTTTACCT
GACAGAGTCATAACGGTTTGTGTAAAAATGTGGTCAGGGACCTTTTTTGTTCTTTCTGATTAGTTAATACTGTACATTGTAACCAGGAGG
GGCAGTTTTGCCAACCAGCCTCTGCTCATGGTCACCATATGTGTATGACAAGGCCTGAGTGAGTTCCTGCATAAACTGGGTAGTGGGCTC
TTTTGACACATTTGCAAGCATGTAAATGAATGAATGACACTACCAGCAACCATCTGTACAGGTCCATTTACTTACATTCATAAGGTTTAT
GCTATGAAACTTCTTCTCATTGTGATGTCAGTAACAGAGTTAGTGTCTCTGATGGAATAGTGTACCTGTCACCCAAGTTATTTTGTTCCT
TTTTGGGTCCTCCAGTATAATCCCCCCCTCATCCCAATTAACTGTAAAATGTTTTACACATCACATTTTTTATACTGTAAACTTGGAAAA

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000310260_chr1_116206282_+_2110nt
CTGGGGCGCAGAGCAGCGGCGGGAGGAGGCGGACACGTGGCAACAGCGGTAGCAGCCCGGGCGGCGGCAGCAACAGCGGCGGCGGCATCG
GCCCGAGCCGCCGGCCGCCCTCCCACCCTCCCGCCCCGCGGCAGCCCTAGCTCCCTCCACTTGGCTCCCCTGGTCCCGCTCGCTCGGCCG
GGAGCTGCTCTGTGCTTTTCTCTCTGATTCTCCAGCGACAGGACCCGGCGCCGGGCACTGAGCACCGCCACCATGGGGAAGGGGGATGAC
AACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGGATCAGCAAGGACATGGAG
GACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTCCTCACCCCTATTGCCTTC
ATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATCTCCATGGCATTCAAACTC
CTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTGTTTCGTGCCCTTTTGTTG
GTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGGAATTACCAGGGCATTGTG
CAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGGCAGCTGCAGCCCATGTTC
ACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGAGCAGCATTGGTGGTCCTA
GAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAA
GTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCAC
AACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATC
CACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCC
ATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGC
ATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCT
ACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTC
GTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCT
GAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGGGTG
TCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAGGAA
GCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTTCTG
TTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCCCCG
TTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGTATT

>In-frame_ATP1A1_ENST00000295598_chr1_116916145_+_VANGL1_ENST00000369509_chr1_116206282_+_2110nt
CTGGGGCGCAGAGCAGCGGCGGGAGGAGGCGGACACGTGGCAACAGCGGTAGCAGCCCGGGCGGCGGCAGCAACAGCGGCGGCGGCATCG
GCCCGAGCCGCCGGCCGCCCTCCCACCCTCCCGCCCCGCGGCAGCCCTAGCTCCCTCCACTTGGCTCCCCTGGTCCCGCTCGCTCGGCCG
GGAGCTGCTCTGTGCTTTTCTCTCTGATTCTCCAGCGACAGGACCCGGCGCCGGGCACTGAGCACCGCCACCATGGGGAAGGGGGATGAC
AACTGGGGAGAGACCACCACGGCCATCACAGGCACCTCGGAGCACAGCATATCCCAAGAGGACATTGCCAGGATCAGCAAGGACATGGAG
GACAGCGTGGGGCTGGATTGCAAACGCTACCTGGGCCTCACCGTCGCCTCTTTTCTTGGACTTCTAGTTTTCCTCACCCCTATTGCCTTC
ATCCTTTTACCTCCGATCCTGTGGAGGGATGAGCTGGAGCCTTGTGGCACAATTTGTGAGGGGCTCTTTATCTCCATGGCATTCAAACTC
CTCATTCTGCTCATAGGGACCTGGGCACTTTTTTTCCGCAAGCGGAGAGCTGACATGCCACGGGTGTTTGTGTTTCGTGCCCTTTTGTTG
GTCCTCATCTTTCTCTTTGTGGTTTCCTATTGGCTTTTTTACGGGGTCCGCATTTTGGACTCTCGGGACCGGAATTACCAGGGCATTGTG
CAATATGCAGTCTCCCTTGTGGATGCCCTCCTCTTCATCCATTACCTGGCCATCGTCCTGCTGGAGCTCAGGCAGCTGCAGCCCATGTTC
ACGCTGCAGGTGGTCCGCTCCACCGATGGCGAGTCCCGCTTCTACAGCCTGGGACACCTGAGTATCCAGCGAGCAGCATTGGTGGTCCTA
GAAAATTACTACAAAGATTTCACCATCTATAACCCAAACCTCCTAACAGCCTCCAAATTCCGAGCAGCCAAGCATATGGCCGGGCTGAAA
GTCTACAATGTAGATGGCCCCAGTAACAATGCCACTGGCCAGTCCCGGGCCATGATTGCTGCAGCTGCTCGGCGCAGGGACTCAAGCCAC
AACGAGTTGTATTATGAAGAGGCCGAACATGAACGGCGAGTAAAGAAGCGGAAAGCAAGGCTGGTGGTTGCAGTGGAAGAGGCCTTCATC
CACATTCAGCGTCTCCAGGCTGAGGAGCAGCAGAAAGCCCCAGGGGAGGTGATGGACCCTAGGGAGGCCGCCCAGGCCATTTTCCCCTCC
ATGGCCAGGGCTCTCCAGAAGTACCTGCGCATCACCCGGCAGCAGAACTACCACAGCATGGAGAGCATCCTGCAGCACCTGGCCTTCTGC
ATCACCAACGGCATGACCCCCAAGGCCTTCCTAGAACGGTACCTCAGTGCGGGCCCCACCCTGCAATATGACAAGGACCGCTGGCTCTCT
ACACAGTGGAGGCTTGTCAGTGATGAGGCTGTGACTAATGGATTACGGGATGGAATTGTGTTCGTCCTTAAGTGCTTGGACTTCAGCCTC
GTAGTCAATGTGAAGAAAATTCCATTCATCATACTCTCTGAAGAGTTCATAGACCCCAAATCTCACAAATTTGTCCTTCGCTTACAGTCT
GAGACATCCGTTTAAAAGTTCTATATTTGTGGCTTTATTAAAAAAAAAAGAAAAATATATAGAGAGATATATATCTATGCCAGAGGGGTG
TCTTTTTTAAAAATTCTTCTTCATTGCTGACTGAAACTGGCAGATGATTGACCAGTATCCTTTGACCATCTGCACTTTATTTGGAAGGAA
GCAGGGGCTGTCCACCCTGAAAAAGAGTGACTGATGACATCTGACTTTTGTCGATGGGACTTCTCAAGAAGCCATTCCTTGGAGCTTCTG
TTACAGCTGTAAACCAAAGTGGAGCTGGTGCTTCTTGGGAGCCTCGCCTTACAACTAATTCCTGCCTTTCGTCCAGTACCAAGTCCCCCG
TTGCTTCTGGTCAGCCCACTTGTAGACTTCCAGGGGACACATCTTTATTCTGTTTCAGGAAACCAGTCACGACACGTCCACATATGTATT


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FusionGenePPI for ATP1A1_VANGL1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ATP1A1PRKCA, MAPK1, MAPK3, FXYD1, EZH2, HGS, HDAC5, NDRG1, CDK9, NELFB, NELFCD, NELFA, SIRT7, FBXO25, CUL3, CDK2, AKT1, A2M, PKD1, PKD2, ATF2, IQCB1, MMS19, CLN3, ADRB2, ATP4A, DYRK4, HIPK4, MAPK4, CDK20, EGFR, FBXO6, LGR4, UBC, STAU1, SPRTN, HUWE1, AP2A2, CUL7, CCDC8, ZNRF1, ZNRF2, ILK, IRAK1, LIMK2, PPT1, RPS6KB2, LGALS3, ACADM, AFG3L2, ATP1B1, ATP1B2, ATP1B3, ATP2B1, ATP2B4, ATP6V0D1, CCT6A, CCT8, CLTC, CLTCL1, HADHB, HSD17B12, LMAN1, MTCH1, MTCH2, NDUFS1, PPP2R1A, RAB1A, RAB1B, RAB2A, TPM3, ATP5C1, ATP5L, ATP6V1A, CAD, CCT7, CYB5B, CYC1, DDOST, EIF3B, IPO5, ITGA5, MRPL40, NDUFB8, NDUFS4, NDUFV1, PC, PHB, RPN1, SLC25A3, SSR2, TECR, TMCO1, TMED2, TPM4, UQCRC2, UQCRQ, VDAC1, VDAC2, VDAC3, NTRK1, TCTN3, TMEM17, AHSA1, ERBB2, NCSTN, GOLT1B, TMEM63B, YIPF5, TUBA1C, MBOAT1, KIAA0368, SKI, CRY2, ESRRB, C3orf17, ZNF746, CYLD, NCDN, COX15, PDHA1, SDHA, SOD1VANGL1KBTBD7, RAPGEF5, NT5C3A, GMFG, SMYD3, THAP2, SRPK1, FBXW11, CCDC8, SPRY2, ZRANB2, LUC7L, EPB41L3, RASSF9, RASSF10, TCTN3, EVC2, TMEM17, TMEM216, NAF1, VANGL2, PTPN3, GPR156, CD44, DVL3, SDC2, PNN, TNFRSF1A, MANSC1, SDC1, PRICKLE3, NXF2, EPB41L5, CD83, JPH4, FGF8, ZC3H18, TRIM25, RNF41, ERBB4


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ATP1A1_VANGL1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneATP1A1P05023DB00390DigoxinSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved
HgeneATP1A1P05023DB00511AcetyldigitoxinSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved
HgeneATP1A1P05023DB01078DeslanosideSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved
HgeneATP1A1P05023DB01092OuabainSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved
HgeneATP1A1P05023DB01119DiazoxideSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved
HgeneATP1A1P05023DB01430AlmitrineSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved
HgeneATP1A1P05023DB00774HydroflumethiazideSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|investigational
HgeneATP1A1P05023DB00903Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|investigational
HgeneATP1A1P05023DB01188CiclopiroxSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|investigational
HgeneATP1A1P05023DB01345PotassiumSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|investigational
HgeneATP1A1P05023DB01370AluminiumSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|investigational
HgeneATP1A1P05023DB01396DigitoxinSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|investigational
HgeneATP1A1P05023DB01378MagnesiumSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|nutraceutical
HgeneATP1A1P05023DB01021TrichlormethiazideSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|vet_approved
HgeneATP1A1P05023DB01244BepridilSodium/potassium-transporting ATPase subunit alpha-1small moleculeapproved|withdrawn

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RelatedDiseases for ATP1A1_VANGL1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneATP1A1C0001430Adenoma2CTD_human
HgeneATP1A1C0005586Bipolar Disorder1PSYGENET
HgeneATP1A1C0020428Hyperaldosteronism1CTD_human
HgeneATP1A1C0020538Hypertensive disease1CTD_human
HgeneATP1A1C0042594Vestibular Diseases1CTD_human
HgeneATP1A1C0151744Myocardial Ischemia1CTD_human
TgeneVANGL1C0027794Neural Tube Defects2CTD_human
TgeneVANGL1C1838568Sacral defect and anterior sacral meningocele1CTD_human;UNIPROT
TgeneVANGL1C3891448NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO1UNIPROT