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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 32931

FusionGeneSummary for SDC3_ZNF827

check button Fusion gene summary
Fusion gene informationFusion gene name: SDC3_ZNF827
Fusion gene ID: 32931
HgeneTgene
Gene symbol

SDC3

ZNF827

Gene ID

9672

152485

Gene namesyndecan 3zinc finger protein 827
SynonymsSDCN|SYND3-
Cytomap

1p35.2

4q31.21-q31.22

Type of geneprotein-codingprotein-coding
Descriptionsyndecan-3N-syndecansyndecan neural typesyndecan proteoglycan 3zinc finger protein 827
Modification date2018052320180523
UniProtAcc

O75056

Q17R98

Ensembl transtripts involved in fusion geneENST00000336798, ENST00000339394, 
ENST00000471567, 		ENST00000508784, 
ENST00000513320, ENST00000379448, 
ENST00000511534, 
Fusion gene scores* DoF score4 X 2 X 3=2410 X 4 X 7=280
# samples 410
** MAII scorelog2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(10/280*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SDC3 [Title/Abstract] AND ZNF827 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLGGTCGA-HT-8564-01ASDC3chr1

31342314

-ZNF827chr4

146859787

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000336798ENST00000508784SDC3chr1

31342314

-ZNF827chr4

146859787

-
5CDS-intronENST00000336798ENST00000513320SDC3chr1

31342314

-ZNF827chr4

146859787

-
5CDS-intronENST00000336798ENST00000379448SDC3chr1

31342314

-ZNF827chr4

146859787

-
5CDS-intronENST00000336798ENST00000511534SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-3CDSENST00000339394ENST00000508784SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-intronENST00000339394ENST00000513320SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-intronENST00000339394ENST00000379448SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-intronENST00000339394ENST00000511534SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-3CDSENST00000471567ENST00000508784SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-intronENST00000471567ENST00000513320SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-intronENST00000471567ENST00000379448SDC3chr1

31342314

-ZNF827chr4

146859787

-
intron-intronENST00000471567ENST00000511534SDC3chr1

31342314

-ZNF827chr4

146859787

-

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FusionProtFeatures for SDC3_ZNF827


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SDC3

O75056

ZNF827

Q17R98

Cell surface proteoglycan that may bear heparan sulfate(By similarity). May have a role in the organization of cell shapeby affecting the actin cytoskeleton, possibly by transferringsignals from the cell surface in a sugar-dependent mechanism.{ECO:0000250, ECO:0000269|PubMed:11527150}. May be involved in transcriptional regulation.{ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015311_354-22995Compositional biasNote=Pro-rich
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015961_972-22995Compositional biasNote=Poly-Ser
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115311_354141976Compositional biasNote=Pro-rich
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115961_972141976Compositional biasNote=Poly-Ser
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-0151019_1041-22995Zinc fingerC2H2-type 8
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-0151047_1069-22995Zinc fingerC2H2-type 9
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015374_396-22995Zinc fingerC2H2-type 1
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015402_424-22995Zinc fingerC2H2-type 2
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015433_455-22995Zinc fingerC2H2-type 3
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015817_839-22995Zinc fingerC2H2-type 4
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015845_867-22995Zinc fingerC2H2-type 5
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015897_919-22995Zinc fingerC2H2-type 6
TgeneZNF827chr1:31342314chr4:146859787ENST00000379448-015929_952-22995Zinc fingerC2H2-type 7
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--1151019_1041141976Zinc fingerC2H2-type 8
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--1151047_1069141976Zinc fingerC2H2-type 9
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115374_396141976Zinc fingerC2H2-type 1
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115402_424141976Zinc fingerC2H2-type 2
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115433_455141976Zinc fingerC2H2-type 3
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115817_839141976Zinc fingerC2H2-type 4
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115845_867141976Zinc fingerC2H2-type 5
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115897_919141976Zinc fingerC2H2-type 6
TgeneZNF827chr1:31342314chr4:146859787ENST00000508784--115929_952141976Zinc fingerC2H2-type 7

- In-frame and not-retained protein feature among the 13 regional features.
>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSDC3chr1:31342314chr4:146859787ENST00000339394-15115_302-59443Compositional biasNote=Ser/Thr-rich (mucin-like)
HgeneSDC3chr1:31342314chr4:146859787ENST00000339394-151_387-59443Topological domainExtracellular
HgeneSDC3chr1:31342314chr4:146859787ENST00000339394-15409_442-59443Topological domainCytoplasmic
HgeneSDC3chr1:31342314chr4:146859787ENST00000339394-15388_408-59443TransmembraneHelical


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FusionGeneSequence for SDC3_ZNF827


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SDC3_ENST00000336798_chr1_31342314_-_ZNF827_ENST00000508784_chr4_146859787_-_0aa


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SDC3_ENST00000336798_chr1_31342314_-_ZNF827_ENST00000508784_chr4_146859787_-_0nt


* Fusion transcript sequences (Full-length transcript).
>In-frame_SDC3_ENST00000336798_chr1_31342314_-_ZNF827_ENST00000508784_chr4_146859787_-_13855nt
GCCCAGCGCTGGCGCAGTGAGAACTTCGAGAGACCCGTGGACCTGGAGGGCTCTGGGGATGATGACTCCTTTCCCGATGATGAACTGGAT
GACCTCTACTCGGGGTCGGGCTCGGGCTGTAAGTACCCCCCTCCCTACCTCTGCCTGGGGGCAGTGACCAGTCTGTATCCAGCCTCAACT
CTGAGAAGCCCACGGGGGGCTTGCTTCAGTGAGGCAGGGGGCATTCACTGCCTGGGTCAGGCAAGTTCTTCTTGCTCTGGATCCCCAGAA
CAAGAAGGGCAGAACATCCTTCTGGGGATAGAACAAGACCTGGGAGGACCTCAGGGCCCAGAATGTCCAGGTCTCCAGGGTCCCACGTCT
GCATCTTTGTGTGTGCTATGTGGCTTTCTCTGCAGACCTTGCTTGGTTCCGGTGGTCCCGTCAGGTGCAATAAGCTGTGGCCAATGGTGG
GGTTAGGGCAGTGATGACACAGGGCAGGTGCTTCAAGTGGTGCCTGGGATGGCCCCGCCCTGGGGAAGGGGAGCCAGGTCAGCTGGGTCT
AGCAGAATCTCGGGAGAGAAGGGCACCGCGAACCCCACTCTGCCATGTAGCAACTGTGTGCCCCTCGGTGCTCCCCCTCCCTGAATCCCT
GTATTTTCACCTGTGGATGGTGAGAAATACGACTTCTTCTCAGTGCCTCTAGGAGGGTTTGGGATAGGAAGCTGGGGTCTGGCACAGAGG
AGGAGCTCTCAAAATGGTAGCAAAAAGAAGGCAGCTGAGACTGGGCCCAGTGAGGGCACGGGCTGGCATCTGAGGAGATGGTACGGGGTC
TGCACGCCACAGAGCTGGCTCCCCACAGCCCTCGCCTCTGGTCTCCCCTCCTTAGCCAAGTCCTTTGAGCCTCTTTCAAATTAATCTTTG
TAAAACCCGTTTATATTGGGTCACATCTCTATTCGCAAAGTTCCCTGGCTCCCCTCCCTCCTGCCTGGTTCCGAGCCCAGGAGCTGGCTG
TGGCTTCTCCCTCCCCCATCCCCTACTCCCCATCTCATTTCCTCCCAAGTTCCTTCACTGTCCCGGCTTTGCGTCAGCCAGATTGCTCAA
GCAGTTCCCCTGCCTCAAGGGCTTCTTTTCCCTTTTACCCTCCGCCTCTGCCTCTGGGGGAAGCCCTTAGTGTACCACCCCTGCCTTGAG
CTTGTGGTAGGGGTGCCTTTGGGGTCTGACTCTTCCCAGAATGCCACTCCTGTGTTCCCCTGCAAGCCCCAGCAAGTTTTGCAGCCAGTA
GCGCCTCAGTTGCTGCTGCCTGGATTCAACCTCATAGAAACTGTAGGCTGGGTGGGCAGGAATAGTCAAGGAAGGCTTCCCGGGAGAGGC
GGCCCCCAGAATTTTTGACTTGGCAGAGAGAAGTTGGGGAACATCAGCAACTGACCACCTTTAGCTGGGCTGTGCCTTCCTCCTTTCTCT
CATCTTTTCTGGGAAAATTGGGTAAAGAGAGGGGGTTGGGAGACCTAATCTTGATGGCCATTGCTTACCTGGGATCCTCATGCCCCTCAC
AACCACCCAGCTCCCTAGCTCTCTCCCTCTCCCCCACCCCCTCAGACTTCGAGCAGGAGTCGGGCATTGAGACAGCCATGCGCTTCAGCC
CAGATGTAGCCCTGGCGGTGTCCACCACACCTGCGGTGCTGCCCACCACGAACATCCAGCCTGTGGGCACACCATTTGAAGAGCTCCCCT
CTGAGCGCCCCACCCTGGAGCCAGCCACCAGCCCCCTGGTGGTGACAGAAGTCCCGGAAGAGCCCAGCCAGAGAGCCACCACCGTCTCCA
CTACCATGGCTACCACTGCTGCCACAAGCACAGGGGACCCGACTGTGGCCACAGTGCCTGCCACAGTGGCCACCGCCACCCCCAGCACCC
CTGCAGCACCCCCTTTTACGGCCACCACTGCTGTTATAAGGACCACTGGCGTACGGAGGCTTCTGCCTCTCCCACTGACCACAGTGGCTA
CGGCACGGGCCACTACCCCCGAGGCGCCCTCCCCGCCCACCACGGCGGCTGTCTTGGACACCGAGGCCCCAACACCCAGGCTGGTCAGCA
CAGCTACCTCCCGGCCAAGAGCCCTTCCCAGGCCGGCCACCACCCAGGAGCCTGACATCCCTGAGAGGAGCACCCTGCCCCTGGGGACCA
CTGCCCCTGGACCCACAGAGGTGGCTCAGACCCCAACTCCAGAGACCTTCCTGACCACAATCCGGGATGAGCCAGAGGTTCCGGTGAGTG
GGGGGCCCAGTGGAGACTTCGAGCTGCCAGAAGAAGAGACCACACAACCAGACACAGCCAATGAGGTGGTAGCTGTGGGAGGGGCTGCGG
CCAAGGCATCATCTCCACCTGGGACACTGCCCAAGGGTGCCCGCCCGGGCCCTGGCCTCCTGGACAATGCCATCGACTCGGGCAGCTCAG
CTGCTCAGCTGCCTCAGAAGAGTATCCTGGAGCGGAAGGAGGTGCTCGTAGCTGTGATTGTGGGCGGGGTGGTGGGCGCCCTCTTTGCTG
CCTTCTTGGTCACACTGCTCATCTATCGTATGAAGAAAAAGGATGAGGGCAGCTACACGCTGGAGGAACCCAAGCAGGCGAGCGTCACAT
ACCAGAAGCCTGACAAGCAGGAGGAGTTCTATGCCTAGTGGAGCCACAGTGCCTCCCTGCAGCCTCAACACCACCCTGCTGTCCAGTCCC
CAGCCTGGCCCCACCAGCCCAAGCCTGGGACTGGGCCTGGAACCTGGCCCCAGTTCTTCTCTGCCCTCTCTCCCAAGGTCTGCCCAGGCT
GCCAGCCTCACACAGATCTTCCCCGAGGAAGAGGGGCTGCTGCCATCTGCCCCAGACTGTGCCCTTACGAGCTCATCTCTTGTTCCCCTC
ATCCCTGCCACCAGTCTGGGGCTTCAGGACCTCATGTCAGATGGATGGGAGGAAGAAAGCTCCTGATTGGCTGGTGGTGGAAGAAAGGGT
GGGGCTTGAGATGAGCCTGAGCCCTGACTTGGCACCCACAGTGCTCACTGAGATCTCCTTTTTGGGGCAGAGAGGCACTCAGGCTGGTTT
CCAGGACAAACATTTGGTAAACACAGCCCTTGAAATCATCTAGACACTGCAACCTCTTGCTCGTATCCCAGGGCCTCTCTCTAGCTGGGT
GAGAGGGTGTCCCTTGTCACCAGCCTGTTTTGTCCTGGTCTCTCTGGGGTTGTTGAATCTCTCCTCTTGCCTGCCAAGTACACATGTACC
CAGACTTCATTTCTTTCTGCATCTTCCCCCAAGAAACAGCTTCCTGAGGGTGCTGGGGCAGCCACTGGTGAGGAGGGGCTGCTCTGATGT
CCCTCCTATGAGGGGACTCTGCACAGACACCATTGCCCACACTATCACCATATTTTCACTCAGTCACACACAAGACAAAAGCATGCAATG
ACAAAACCATACGCAATCCTGACCGCCCAGCCAATCAAGACATATCACAGAACACACGCGTCCTTCCAAGAATGTTTATCCTCATGCATC
ACTTACACACCCCCAGACACGTACTGCAATGCAAGTCACTAGTCATGGTCACATGACAGTGACAGTGTGGCCTCCTCCTACCCCAAATAC
ACCCACACTCTGGCACCACACACATTGTCTCCAGCTTTCAGGCTTACTGGGGAGGGTGGAATCGAGCCAGAACAATCAGCCCATATTGGG
TCCCCCTAAGTTGCCCCGTCATACTCAGTCCCATGCCATGGTGCCCACACCAACCATGCAGCCGCCAACCCCAGCCAGTGTCAGACACAA
TCCCATGTGGATGCACAGTCTCACTCCACATGACCTGCTCTCAATGCTGGAGGGAAACAGGCAGGCCCTTGCCTTTCTCGGAAAAAGTGT
GGGGCCACAGCCCTTTTAGGGCATTGCATGCAGGTGGGCCTGGCTTCACCCCTACCTGCTTCCTCCCCACCGCAGCTGGCAGAGGGGGAG
GTTTGGGGCCAGACCCCCACTAGCTGGGAGCCTGGGGGCTCCTCTAAGGCTGAGGAAGGAAATTTGGCCCCAGGTTGTTGGGGGGTCTTG
GGTCTCCCAGGACGGAAGGCCCAGGGCAGGGAGGGGGCATGTGGTTGGGCTCCTTTATCTCCCTGTGTCCCCTTCCTGCTTTGAGCTAGG
GGGCTGACTCTGCCTCCCAGGACACAAGTCTCCAAAGTGCCTGTGAGGGCGGGCCCTCCGCACCCTCTGCCCTCTGCCTGGCAGGCCAAC
CTCAGCCCACCTGCCCAGAGGCCCTCCCTGTGGACACCCCCTCACCTATTTGGCCAAACAATTCTGGCTGCAGCTTCAGGGGCCATGGCT
GGAAGCAGCCCCTGCAGATCCCTCAGGCCCCGAGGTCAGGGTTTGAGGGATGAGACCAGGTGATAGTGGGGGAGGGGTTACTTCCTTTGT
TACCTAGCAAGTAGGGCTATTTCCATCGGTATTTTAAATGTGGGGTCACAGATCTTTTGGGGAGGGTGTGCTTGGCAGGGGGCCTCTTGG
AGCCAAAGGGATGTGGTGTGAGTTGCGATTGGCTGGCACTCACACCCCCACCCCTCACCCACATCCCAGATTCAAGTCAGGAAGGCAGGT
TTTATTTCAGGGCCCTTTTCAAGATGCCCTGGCAGCAGATTTCTGCAGGATGAGGGGTAGCGGTGTGTAGGCAGTGAGGGGGAGGTTCCA
GGGGCTGTCCCACAGCCTGTCTTTTCCAGGCTGGGCTCCATCTTCCAGTCCCAAAACCCTCCTTCACAGGGCCCAGAGGCTTGTGAGGAA
GCCAGGTGGACCCAGCCTTAGAAGAGTGGGCATGGGGGGCCCCTGATATCTGGAGGGGGCGGGTTGGCCTCAGTCATCTTTGGAGCAGAA
GGGCTGGGTCCTGGGGCCACAGACCACAAGGCTCAGCCTCCCTACCCTGCTCCCTGGGGTGCTGCTGTCTTGGAGAGCACAGCTCTGGTG
AGACGGCCTGGGCAGGCCGAGGCTGAGAAACCAGGGAGGATAGAGGAGAAAAGGGCTTGGGCCCCCAGCCCCAGAAGATGCTGGACCCCA
GGTGGGAGACCCAACAGTGGGTGCAGTTTCTCAGTAGGGCTGGAGCCAATGGTGGGGGTGGCCCCGGCAGGCCTGGCTCCTCACATCCCA
GGGGTTGGCTTCTGATTTGGGGCTTGGGCTCCAGGCACTGGCTTCTCTTCTCTGTGTCCTTAGCATTTGAGAGAAGAGGCCAGGGGCCTT
GTTCATGGATCCCTGGACCCAAGGCAGATGTCCAGGCTTTATCCTCCTGAGGATGAGGAGTCTGACCAGCCCAAATCTGCCCTGGCCGGC
CTGACCGGGGCAAGGCAGTCCAAGAGAGTTCAGTGAGGACCAGCTAGGCTCTCCCAGGTGCAATGTGGGTGCAGGGCCCTCATGTCCCCC
TACCCCTGCCTGTGATGGAGTGTTCTGAGGGGCTTTGGCATTTGCTGGAAGCACAGGGAGTTCCAAATGAGAGGGAGCTTCTGTGGCTTG
AGAGCCTCTGGGGCCTTGGCTGCCAGAGCACGAGGCAGGCCAGGACCTGGAGAGCCCAGACCCTGTCTCCAGGAGGCCAGGAGGCCAGAT
GGGGGCCTTGCCTGAAAGACTGGTCCCCTTGATCGCTGGAGGCATGTGGGTGGCAACCAGGGCTGGGCAGGGCTTAGGGTGTGTGGGCCA
AACCCCCCTGGGGTTGGCAAAGCCGCCTGTCAGGCCTCCTGGTGGGGGCCCCTGGACACAGGGAGCAGACCCTCTGCCTCATGGGGTAGG
AGTGGCTGCCTCCTGTGTTCTCTGGATTTCTTCTCCCAACAACTACAACCCTGGACTTGCCTCCCCAGGCCTCTTGCCTGTAAATAGAAG
CCCGCAAACTGTACAGATTTACAGAGGCATCGAGACTGGGCCCTGGGAGTTGCCATCTGAGAGCCGATGGCCCCAGCATCCCCCAGGTGC
CTGCCTGGCACCACAGTGACCCTGGCCTCAGCGTGGCAAATGCATGTAAATATTTTTCGTAGGCAGCGTGGCTCCAGAGAGCCCCCTGAA
GACAGTGTCCCTCCCTCCTGTGAGTCCTTTCTCCTGTACAGAACCTGCCTGGGGTGGGTGGGGGTCTGCCATTCCCTCCCCCAGGCCTTC
CCTGCCCCTTCTCTCCCCTGTAACCTGTTTATTAACCATACCTGTCCTGAGTTCATGGCCAAAACCTTAAATAAGAAAAACAAAAGAAAA
AGACAGTGGAAAAAAGAGACCAAGGCGCCTGCCCCACTGCGGGTACTCTCCTGTTCCAGCCTTGTGAAGGAACTGGTTTTGTTTTTGTTT
TTTTTTTTTTTTTTTTTTTTTTGTTTGTTTGTTTTTTTAACACTTCCTGTGCTGTGCCCATTTATAAGAGGAAATAAAATTAAGCTGAAA
TGAAAAAAAAAAAAAGGAAAAAAGAAAGGAAAGAAAAGAAGAAAACCCCTCTTCTGGCTCCAGGAAACAAGCTTCAACCCATTGCACACA
CCGGAGAAGGGGTTTCCCCCTGCCCGCCCGCCCGCCCCCCAACTACCTCCCCGCTCCTGCCAGTGTCTGCCTCTCTGCCCCCACGGGGGT
TTATTTGATCTCACATTAACCAAGGAGGAGAATGTGAGAAAAGGGGGAAAATGCCCAGGAGGAAGCAGGAGCAGCCCAAGCGCCTTCCCT
CACATGTTAGTAGGCAGGAAGAGGCGGAGGGAGAGCTCAGTGAAGGAGAACACTGGTATGGAAACTCTTCAGAGACTCCGTCAGAAGCAT
CCTATGGGGAAGTCCAGGAGAACTATAAGTTGTCTCTGGAGGACCGGATCCAGGAGCAGTCCACGTCCCCGGACACCTCCTTGGGAAGCA
CGACTCCCAGCAGCCACACGTTGGAGCTGGTGGCACTGGACAGTGAGGTCCTGCGAGACTCACTGCAGTGTCAAGATCACCTTTCCCCGG
GAGTGTCTTCTTTGTGTGACGATGACCCAGGCTCCAACAAGCCCCTGAGCAGCAATTTGAGGCGGCTGCTGGAGGCTGGTTCCCTCAAAC
TCGATGCTGCAGCCACGGCTAATGGCAGAGTGGAGTCCCCCGTAAACGTTGGCTCGAACCTCTCCTTTTCCCCGCCTTCCCACCACGCCC
AGCAGCTCAGTGTTCTGGCCAGGAAGTTGGCCGAGAAGCAGGAACAGAATGACCAATACACTCCAAGTAACCGTTTTATATGGAATCAAG
GTAAGTGGTTGCCAAACTCAACCACCACCTGCAGCTTGTCTCCGGATTCAGCCATCCTAAAACTGAAAGCTGCAGCCAATGCCGTTCTGC
AGGACAAATCTCTCACCAGGACTGAGGAGACCATGCGATTTGAGTCCTTTTCCTCCCCTTTTAGCTCCCAGTCTGCCAGTTCTACCTTGG
CCGCTTTGTCCAAGAAGGTCAGTGAAAGAAGTTTGACTCCTGGTCAGGAGCACCCTCCACCGGCCAGCTCCTTCCTTTCCCTGGCTTCTA
TGACCTCCTCAGCGGCCCTTCTGAAGGAGGTGGCCGCAAGGGCTGCGGGCAGTCTTCTGGCTGAGAAATCATCGCTGCTGCCTGAGGACC
CTCTACCGCCCCCGCCTTCAGAGAAGAAACCAGAAAAAGTCACTCCGCCACCTCCACCGCCACCTCCACCACCTCCACCACCACCACCAC
AATCCCTGGAATTATTATTACTCCCAGTTCCTAAGGGAAGAGTTTCTAAACCCTCCAATTCAGCCTCAGAAGAGGAAAGTGGAAAGCCTT
TCCAGTGTCCAATATGTGGTTTGGTTATTAAAAGGAAGAGTTACTGGAAGCGGCACATGGTGATTCACACAGGTTTAAAAAGTCATCAGT
GTCCGCTCTGTCCATTCCGGTGTGCTCGCAAGGACAATCTCAAATCCCACATGAAGGTTCATCAGCACCAGGATCGGGGAGAGACCTTTC
AGTGCCAGCTGTGCCCTTTTACTTCCTCACGCCACTTCAGCCTGAAACTCCACATGCGTTGCCATCAGCACTTCCTGAGGACAGAAGCCA
AGGTGAAGGAGGAGATCCCAGACCCAGATGTCAAGGGATCTCCCCACCTCAGTGACAGTGCCTGCCTGGGGCAGCAAAGGGAAGGAGGAG
GGACAGAGCTAGTGGGGACCATGATGACGTCTAACACTCCAGAGAGGACTAGCCAGGGAGGGGCTGGCGTCTCGCCTTTGCTGGTGAAGG
AGGAACCCAAGGAAGATAACGGCCTGCCCACCTCCTTTACTTTGAATGCTGCCGACAGGCCCGCCAACCACACAAAGCTGAAAGACCCCT
CCGAGTATGTGGCCAACAGTGCGTCAGCATTGTTCAGCCAGGACATCTCTGTTAAGATGGCGTCTGATTTTCTCATGAAGCTGTCAGCTG
CAAATCAGAAGGAGCCCATGAATCTTAATTTTAAAGTGAAAGAGGAGCCTAAGGAAGGGGAGTCCCTAAGCACGACTTTGCCTCGGTCCA
GCTATGTGTTCAGCCCGGAATCTGAAGTGTCAGCCCCAGGCGTCTCTGAGGACGCACTAAAGCCCCAGGAAGGGAAGGGAAGTGTGCTAA
GGCGGGATGTGTCAGTCAAAGCAGCCTCTGAACTTCTCATGAAACTCTCAGCGGAAAGCTACAAGGAAACACAGATGGTGAAGATTAAAG
AGGAACCCATGGAGGTTGACATCCAGGACTCCCATGTCTCGATATCACCCAGCCGGAATGTTGGCTACAGCACTTTAATCGGGCGAGAGA
AAACCGAACCCTTACAGAAGATGCCAGAGGGCAGAGTACCCCCAGAGAGAAACCTCTTCAGTCAGGATATCTCTGTGAAAATGGCTTCCG
AGCTCCTCTTTCAACTGTCAGAAAAAGTGAGCAAAGAGCACAATCATACAAAAGAAAACACCATCCGGACCACGACCAGCCCTTTCTTTT
CAGAAGACACATTTAGACAATCACCATTCACCTCCAATTCAAAAGAACTGCTGCCCAGTGACTCCGTGCTGCACGGAAGAATATCAGCTC
CAGAAACAGAAAAGATAGTCCTAGAGGCAGGAAATGGATTACCATCCTGGAAATTCAATGACCAGCTTTTTCCCTGTGACGTGTGTGGGA
AAGTGTTTGGCCGACAGCAGACATTGTCCCGACACCTCTCGCTGCACACAGAGGAAAGAAAATACAAATGCCACTTGTGCCCCTATGCTG
CTAAGTGCCGTGCAAATCTGAACCAGCACTTGACCGTCCATTCCGTGAAGCTGGTGAGTACAGACACCGAGGACATTGTCAGCGCCGTCA
CCTCTGAAGGCAGTGATGGGAAGAAACATCCTTATTATTACAGTTGTCACGTGTGTGGATTTGAGACCGAGCTCAATGTCCAGTTTGTCA
GCCACATGTCACTCCACGTGGACAAGGAGCAGTGGATGTTTTCGATCTGCTGCACTGCCTGCGACTTCGTCACCATGGAGGAAGCAGAGA
TAAAGACTCACATTGGCACCAAGCACACAGGGGAAGACAGGAAGACCCCCAGCGAATCAAATAGCCCCTCTTCATCCTCCCTCTCAGCTC
TGAGTGATTCAGCCAACAGCAAAGATGATTCAGATGGCTCCCAGAAAAACAAGGGCGGGAACAATCTGCTGGTCATCTCTGTCATGCCTG
GGAGCCAGCCCTCACTGAACAGTGAGGAAAAGCCAGAGAAAGGGTTCGAATGTGTTTTTTGCAACTTTGTCTGCAAGACGAAGAACATGT
TTGAGCGTCATCTGCAGATACACCTCATCACCCGGATGTTTGAGTGTGATGTGTGCCACAAGTTCATGAAGACCCCCGAACAGCTGCTGG
AGCATAAGAAATGCCACACTGTCCCCACCGGTGGGCTCAACTCAGGACAGTGGTGAGTTTCAGACTCCTCTAGGTGCCCATTCTGCATTT
ATTCCACCAACCGCCCCGCTGCCATGGAGTGCCACCTCAAGACCCACTACAAGATGGAGTACAAGTGCCGGATCTGCCAGACGGTGAAGG
CCAACCAGCTGGAGCTGGAGACGCACACCCGGGAGCACCGCCTGGGCAACCACTACAAGTGCGACCAGTGCGGCTACCTGTCCAAGACCG
CCAACAAGCTCATCGAGCACGTGCGCGTCCACACCGGGGAGCGGCCCTTCCACTGTGACCAGTGCAGCTACAGCTGCAAGCGCAAGGACA
ATCTCAACCTGCACAAGAAGCTGAAGCACGCCCCACGCCAGACCTTCAGCTGCGAAGAGTGCCTGTTCAAGACCACACACCCTTTCGTCT
TCAGCCGCCACGTCAAGAAGCACCAGAGTGGGGACTGCCCCGAGGAGGACAAGAAGGGCCTGTGTCCAGCCCCCAAGGAACCGGCCGGCC
CGGGGGCCCCGCTCCTGGTGGTCGGGAGCTCCCGGAATCTCCTGTCTCCCCTGTCAGTTATGTCTGCCTCCCAGGCTCTGCAGACCGTGG
CCCTGTCGGCAGCCCACGGCAGCAGCTCAGAGCCCAACCTGGCACTCAAGGCTTTGGCCTTCAACGGCTCCCCTTTGCGCTTTGACAAGT
ACCGGAACTCAGATTTTGCCCATCTCATTCCCTTGACAATGTTATACCCCAAGAACCACTTGGATCTCACATTCCACCCTCCCCGACCTC
AGACTGCGCCTCCCAGCATCCCCTCACCCAAACACTCCTTCCTGGCCTATCTCGGACTGAGAGAAAGAGCAGAGACTGTCTGAGGGCAGC
CATGTTCTGTACCAAAAACAGAGAGACAAAAGACAAAAAAAAAAAAAAAAACCACAAAACTTAAACACAACCCCAGCAGGTGTATGTTGC
TGCAAAACCTACAGACCCCGATGGGTCTGGAACATGTGTACTGTATATCTTTAGTAAGGAATAGAAAATTGGCTCTGTGTGTATACCTAT
TGCATTGACCTGAAAGCTGCTTTATCCAATCTTCAGAGAGGTGACCTACTGCATACTTCTACCTTCAGAGGCATGCCTCCCCAGCCACCC
ACTCCCACTCTCAGCCCTTCTCCGTACTTTTCTCTGAAAGGAATCTTGTCTTGTTAAACCCTAAAGAGAGTGTCCTTAATAGCAATCAGC
ACTTGTAAGCTTATATACTGGTGCATTTGGTTTTCTGTTGGGTGAATGCGGTGTGTGGGCGTTTGTGGATTCTGAAAGAGAAAGCCGTGT
GTCGTGTGCCATGACATTTCTATTGCACATTCTTTGTACTGGCTTCTTTAACAGCGATGAACGTTCTTTTCCCTCCTGGGTTGTTCATCC
ACGACAGTCTCTCCCTGTGCTCCTTCATCACCTTTCCCTCTCTCTTTGATGGCTACAGAGTGGTAGGGCCTGGTGCTTAGTCGATGAAGG
AATGGTAGCCATCTACAGTGCTGCTGGAGATTTCCGCCAGAGCGCTGGAGACCTTGCGCTCAGATCTTCTCTGGTGATGAAGAGGCGAGG
AATCAAGTGACTGATCTGGAAGAAATATCTCGCAGCACTGCAGCTAACATCACAGAACTTAAGTGTGTTTTGTGTGTGTGCCCACACGTA
GACAAATGTGTACGGTGCACACACACAGTGCATCATTTTTTAAGGGCAGATTATATATATATATGAGATGTATTAATTCAGTGGTTACCA
TTTGTTTGCAGGAAAAAGAAATGTATGGGTGAAAAAATTTATGGTTGATAAATCCAGCCAAGGAGATTAAAAGGGGTTTGGATAAATTCT
GGGTATAAATGCTCAGACTAAAAAAAAGAAATGGCAGTTTTGCACAGTGCTATGGTCTTGCACTAGTTTTTGTTTCTCATCTGAAAAAAA
AAAAGTAAAATAAAAGGAAGAAAATGTACCTTTTTTATGGAATGAGTAGACTGTATGTTTGAAGATTTAGCCACAACCTCTTTGACATAT
AATGACGCAACAAAAAGGTGCTGTTTAGTCCTATGGTTCAGTTTATGCCCCTGACAAGTTTCCATTGTGTTTTGCCGATCTTCTGGCTAA
TCGTGGTATCCTCCATGTTATTAGTAATTCTGTATTCCATTTTGTTAACGCCTGGTAGATGTAACCTGCTAGGAGGCTAACTTTATACTT
ATTTAAAAGCTCTTATTTTGTGGTCATTAAAATGGCAATTTATGTGCAGCACTTTATTGCAGCAGGAAGCAGGTGTGGGTTGGTTGTAAA
GCTCTTTGCTAATCTTAAAAAGTAATGGGTGATTTAAAAAGAAAAAAGGAAAAAAATCTTTGGCTGAATATGTTCATTGCTTGTATTTTT
AAAACAACAGAATTTCCAGTATGAAACAGGCTGAAAGAGCAGGAAGAAATGTTCTTTGTATAATAATGGGAAGTTTGGAATATAAAAGTT
TATATATTATTTATCTATTGGAGAACTGGTGTACAGGAGGAACATTTTCTTACTGTGTTGCTGTTTTCCATCATGTGTTATCCTAAGAGT
TGGGGTTTTTTAAAATCTGTTTCACCAGGGGAAAATAAAAGCATCCCTAATGTTCTTCCTCTAGTCAGTTTGCTTTGCTGAAAGCTCCCT
GGAAATTAGTACAGTTCTACAGGAAGCCAGAAGACTGTACTGTCTGTCCACACCATGGTCTCCTCAGTCCCCTCCACGCCAGCCCCTCTT
CCCCACACCTAGTAGGTGTGCTACACCTCCCTTTGCCAGTCATCCCGCCATGGATGGGGAGCCTACTTGGTGCCCTGGCAAACCTGTTTA
CACTAAGGAGATGCCCACAGGGAGCGGGAAGCTCCCAAACCCTCAGTCATTCTCCAGCAGAGACCTTTGCTCTTGGCCAGGTTTGAAACG
ATGTTCAACCTCGCCACGTCAATGTCTCAGTAAAAGACACTATAGATAGTTATGGACAATACACTCCAAGAATACTGGGCTTATGGGTGG
GTTGGTTTTTTGTTTTGTTTTGTTTTGTTTTCAAGTCATGTCTTTATCCCCATATAATGGAGAATGTGCCACTTGGCTAATAATGTGTTT
TCAAAACTACAAGTTCAGTGATGACAGGAAAGAGGGCTAAAGTAGTCCCACAGAGGCTGGTAGAAAAGGCGAATCACACTTAAGCACCAG
CAGGTTAAAAACCTGAAAGGGTGGCCCTGACAATTCAGACTATAGGTTTTACAGCATGCCACTTGTGCAATAGGAGGTCTAGGGTTGAAA
CTTTCAAGAACGAGAGGAGGTGAAGGAAGGAGACGTTTACTGCTCAAATGCCATGCATTTCACTGCTTGCCACTGAACTTGTATTTGAAT
GACTTAGTAATGCTTAATATAATTGGGCAACTTTTTTAGCACTTTGGAAAGAGTCATCAATCTTTCTGGTAAATTATAAAAGTTTTCTGA
GTGAGAAAAGGTGTGTTTGGAGTTTGTTTGACTTTTTATATTATTATTGTTATTAATAAAGAAAAAAATCTACAGCATTTTTCAGACTCC
ACCCTAGAAAATATGTACCCCTGAATTTGGTTTGCAGTTTGATACTCAGGGAAGGATGTATTCCATAGATATCCTTTCCGTATAAAACAC
TAACATCTTTGAGAAATTCACCTACCAACTAACTTCAATTGTTGTCACTATGCATTCTTCAATGAAAACTAGCTTATTTTTCCATATAGT
AATGCAGTTAGGGTTCTCAGCACTTTCTTTCTTCTATCCTTTTTTTAACTCTTCATATTATGTTCAGATGATCATACTGTCAAGGTTTGT
GTACATTACTGAAAATTTGTATTGTATAAAGCTTTTTGCATTACGAGGCTGTACAGGGTCATTTTGACAGTAACTGGTATATTCCTTTGC


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FusionGenePPI for SDC3_ZNF827


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SDC3TUBA1A, CTTN, FYN, CSK, TUBB, TUBB2A, FGF2, ARRB1, ARRB2, KRTAP5-9, KRTAP10-3, EFNB2ZNF827PPP1CA, UBE2E1, ATP6V1E1, CHERP, VPS45, UNC80, HDAC1, GATAD2A, GATAD2B, RBBP7, RBBP4, CHD3, CHD4, MTA1, MTA2, MTA3, HDAC2, MCPH1, BRCA1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SDC3_ZNF827


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SDC3_ZNF827


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource