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Center for Computational Systems Medicine
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FusionGeneSummary

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Fusion gene ID: 32809

FusionGeneSummary for SCD5_SEC31A

check button Fusion gene summary
Fusion gene informationFusion gene name: SCD5_SEC31A
Fusion gene ID: 32809
HgeneTgene
Gene symbol

SCD5

SEC31A

Gene ID

79966

22872

Gene namestearoyl-CoA desaturase 5SEC31 homolog A, COPII coat complex component
SynonymsACOD4|FADS4|HSCD5|SCD2|SCD4ABP125|ABP130|HSPC275|HSPC334|SEC31L1
Cytomap

4q21.22

4q21.22

Type of geneprotein-codingprotein-coding
Descriptionstearoyl-CoA desaturase 5acyl-CoA-desaturase 4stearoyl-CoA 9-desaturasestearoyl-CoA desaturase 2stearoyl-CoA desaturase 4protein transport protein Sec31ASEC31 homolog A, COPII coating complex componentSEC31-like protein 1SEC31-related protein Aweb1-like proteinyeast Sec31p homolog
Modification date2018052320180523
UniProtAcc

Q86SK9

O94979

Ensembl transtripts involved in fusion geneENST00000319540, ENST00000273908, 
ENST00000282709, 
ENST00000348405, 
ENST00000513858, ENST00000395310, 
ENST00000443462, ENST00000509142, 
ENST00000326950, ENST00000432794, 
ENST00000311785, ENST00000448323, 
ENST00000505472, ENST00000500777, 
ENST00000508502, ENST00000355196, 
ENST00000264405, ENST00000505984, 
ENST00000508479, ENST00000436790, 
Fusion gene scores* DoF score5 X 2 X 4=408 X 8 X 4=256
# samples 59
** MAII scorelog2(5/40*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(9/256*10)=-1.50814690367033
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SCD5 [Title/Abstract] AND SEC31A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSCD5

GO:0006636

unsaturated fatty acid biosynthetic process

15907797

TgeneSEC31A

GO:0051592

response to calcium ion

17196169

TgeneSEC31A

GO:0090110

cargo loading into COPII-coated vesicle

17499046|18843296


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVACCTCGA-OR-A5J7-01ASCD5chr4

83719459

-SEC31Achr4

83765662

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000319540ENST00000348405SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000513858SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000395310SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000443462SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000509142SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000326950SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000432794SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000311785SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000448323SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000505472SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000500777SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000508502SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000355196SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000264405SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000505984SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000319540ENST00000508479SCD5chr4

83719459

-SEC31Achr4

83765662

-
5CDS-intronENST00000319540ENST00000436790SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000348405SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000513858SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000395310SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000443462SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000509142SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000326950SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000432794SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000311785SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000448323SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000505472SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000500777SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000508502SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000355196SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000264405SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000505984SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000273908ENST00000508479SCD5chr4

83719459

-SEC31Achr4

83765662

-
5CDS-intronENST00000273908ENST00000436790SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000348405SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000513858SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000395310SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000443462SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000509142SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000326950SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000432794SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000311785SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000448323SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000505472SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000500777SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000508502SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000355196SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000264405SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000505984SCD5chr4

83719459

-SEC31Achr4

83765662

-
In-frameENST00000282709ENST00000508479SCD5chr4

83719459

-SEC31Achr4

83765662

-
5CDS-intronENST00000282709ENST00000436790SCD5chr4

83719459

-SEC31Achr4

83765662

-

Top

FusionProtFeatures for SCD5_SEC31A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SCD5

Q86SK9

SEC31A

O94979

Stearyl-CoA desaturase that utilizes O(2) and electronsfrom reduced cytochrome b5 to introduce the first double bond intosaturated fatty acyl-CoA substrates. Catalyzes the insertion of acis double bond at the delta-9 position into fatty acyl-CoAsubstrates including palmitoyl-CoA and stearoyl-CoA(PubMed:15907797, PubMed:15610069). Gives rise to a mixture of16:1 and 18:1 unsaturated fatty acids.{ECO:0000269|PubMed:15610069, ECO:0000269|PubMed:15907797}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-141_4977257Topological domainCytoplasmic
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-1471_7277257Topological domainLumenal
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-151_4977331Topological domainCytoplasmic
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-1571_7277331Topological domainLumenal
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-1450_7077257TransmembraneHelical
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-1550_7077331TransmembraneHelical
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725800_10917951182Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725800_10917951182Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623800_10917951068Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724800_10917951068Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926842_8488341107MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725842_8487951182MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725842_8487951182MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129842_8488341221MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927842_8488341221MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928842_8488341234MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826842_8488291201MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927842_8488341221MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623842_8487951068MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927842_8488341206MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926842_8488341107MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724842_8487951068MotifNote=ALG-2-binding site motif-2 (ABS-2)%2C

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-14131_13577257MotifHistidine box-2
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-14272_27677257MotifHistidine box-3
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-1494_9977257MotifHistidine box-1
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-15131_13577331MotifHistidine box-2
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-15272_27677331MotifHistidine box-3
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-1594_9977331MotifHistidine box-1
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-14215_21577257Topological domainLumenal
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-14239_33077257Topological domainCytoplasmic
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-1494_19377257Topological domainCytoplasmic
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-15215_21577331Topological domainLumenal
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-15239_33077331Topological domainCytoplasmic
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-1594_19377331Topological domainCytoplasmic
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-14194_21477257TransmembraneHelical
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-14216_23877257TransmembraneHelical
HgeneSCD5chr4:83719459chr4:83765662ENST00000273908-1473_9377257TransmembraneHelical
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-15194_21477331TransmembraneHelical
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-15216_23877331TransmembraneHelical
HgeneSCD5chr4:83719459chr4:83765662ENST00000319540-1573_9377331TransmembraneHelical
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926800_10918341107Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129800_10918341221Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927800_10918341221Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928800_10918341234Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826800_10918291201Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927800_10918341221Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927800_10918341206Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926800_10918341107Compositional biasNote=Pro-rich
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926120_1608341107RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926166_2068341107RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926209_2548341107RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926258_2988341107RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926301_3428341107RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-19264_478341107RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-192668_1118341107RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725120_1607951182RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725166_2067951182RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725209_2547951182RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725258_2987951182RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725301_3427951182RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-17254_477951182RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-172568_1117951182RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725120_1607951182RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725166_2067951182RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725209_2547951182RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725258_2987951182RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725301_3427951182RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-17254_477951182RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-172568_1117951182RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129120_1608341221RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129166_2068341221RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129209_2548341221RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129258_2988341221RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129301_3428341221RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-21294_478341221RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-212968_1118341221RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927120_1608341221RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927166_2068341221RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927209_2548341221RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927258_2988341221RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927301_3428341221RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-19274_478341221RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-192768_1118341221RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928120_1608341234RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928166_2068341234RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928209_2548341234RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928258_2988341234RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928301_3428341234RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-19284_478341234RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-192868_1118341234RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826120_1608291201RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826166_2068291201RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826209_2548291201RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826258_2988291201RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826301_3428291201RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-18264_478291201RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-182668_1118291201RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927120_1608341221RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927166_2068341221RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927209_2548341221RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927258_2988341221RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927301_3428341221RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-19274_478341221RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-192768_1118341221RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623120_1607951068RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623166_2067951068RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623209_2547951068RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623258_2987951068RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623301_3427951068RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-16234_477951068RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-162368_1117951068RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927120_1608341206RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927166_2068341206RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927209_2548341206RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927258_2988341206RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927301_3428341206RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-19274_478341206RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-192768_1118341206RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926120_1608341107RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926166_2068341107RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926209_2548341107RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926258_2988341107RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926301_3428341107RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-19264_478341107RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-192668_1118341107RepeatNote=WD 2
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724120_1607951068RepeatNote=WD 3
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724166_2067951068RepeatNote=WD 4
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724209_2547951068RepeatNote=WD 5
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724258_2987951068RepeatNote=WD 6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724301_3427951068RepeatNote=WD 7
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-17244_477951068RepeatNote=WD 1
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-172468_1117951068RepeatNote=WD 2


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FusionGeneSequence for SCD5_SEC31A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for SCD5_SEC31A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SCD5CNDP1, PPP2R1A, UQCRC2, TCTN2, TCTN3SEC31ASEC13, APC, TNNT1, PFDN1, ALG2, STAM, STAM2, CUL3, CDK9, HSPA8, VCAM1, ITGA4, REL, SHMT2, MOV10, NXF1, TFG, SCYL1, C6orf211, ATP6V1C1, ENO2, FDPS, NUDT13, SEC23A, SEC23B, SEC24B, ALDH5A1, ATP6V1D, CBS, CTH, CYB5B, DHX15, HNRNPA1, HSD17B10, NAPRT, NSF, SAR1A, TBCA, TPD52L2, TRIM25, TSTA3, TCEB2, NTRK1, TMEM17, XPO1, TSC22D2, NOP14, SEC23IP, NOC4L, GNPDA1, CCDC88A, BRCA1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725800_11137951182PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725800_11137951182PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623800_11137951068PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724800_11137951068PDCD6


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926800_11138341107PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129800_11138341221PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927800_11138341221PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928800_11138341234PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826800_11138291201PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927800_11138341221PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927800_11138341206PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926800_11138341107PDCD6
TgeneSEC31Achr4:83719459chr4:83765662ENST00000311785-1926161_4718341107SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000326950-1725161_4717951182SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000348405-1725161_4717951182SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000355196-2129161_4718341221SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000395310-1927161_4718341221SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000432794-1928161_4718341234SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000443462-1826161_4718291201SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000448323-1927161_4718341221SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000500777-1623161_4717951068SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000508502-1927161_4718341206SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000509142-1926161_4718341107SEC13
TgeneSEC31Achr4:83719459chr4:83765662ENST00000513858-1724161_4717951068SEC13


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SCD5_SEC31A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SCD5_SEC31A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneSEC31AC0079744Diffuse Large B-Cell Lymphoma1CTD_human