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Fusion gene ID: 32480 |
FusionGeneSummary for S100A2_CXCR5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: S100A2_CXCR5 | Fusion gene ID: 32480 | Hgene | Tgene | Gene symbol | S100A2 | CXCR5 | Gene ID | 6273 | 643 |
| Gene name | S100 calcium binding protein A2 | C-X-C motif chemokine receptor 5 | |
| Synonyms | CAN19|S100L | BLR1|CD185|MDR15 | |
| Cytomap | 1q21.3 | 11q23.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein S100-A2 | C-X-C chemokine receptor type 5Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)Burkitt lymphoma receptor 1, GTP-binding proteinCXC-R5CXCR-5MDR-15chemokine (C-X-C motif) receptor 5monocyte-derived receptor 15 | |
| Modification date | 20180519 | 20180527 | |
| UniProtAcc | P29034 | P32302 | |
| Ensembl transtripts involved in fusion gene | ENST00000368708, ENST00000487430, ENST00000497140, ENST00000368710, ENST00000368709, ENST00000368707, | ENST00000292174, | |
| Fusion gene scores | * DoF score | 8 X 4 X 4=128 | 11 X 3 X 7=231 |
| # samples | 10 | 11 | |
| ** MAII score | log2(10/128*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/231*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: S100A2 [Title/Abstract] AND CXCR5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | HNSC | TCGA-CV-5978-01A | S100A2 | chr1 | 153533819 | - | CXCR5 | chr11 | 118754475 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000368708 | ENST00000292174 | S100A2 | chr1 | 153533819 | - | CXCR5 | chr11 | 118754475 | + |
| Frame-shift | ENST00000487430 | ENST00000292174 | S100A2 | chr1 | 153533819 | - | CXCR5 | chr11 | 118754475 | + |
| In-frame | ENST00000497140 | ENST00000292174 | S100A2 | chr1 | 153533819 | - | CXCR5 | chr11 | 118754475 | + |
| In-frame | ENST00000368710 | ENST00000292174 | S100A2 | chr1 | 153533819 | - | CXCR5 | chr11 | 118754475 | + |
| Frame-shift | ENST00000368709 | ENST00000292174 | S100A2 | chr1 | 153533819 | - | CXCR5 | chr11 | 118754475 | + |
| In-frame | ENST00000368707 | ENST00000292174 | S100A2 | chr1 | 153533819 | - | CXCR5 | chr11 | 118754475 | + |
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FusionProtFeatures for S100A2_CXCR5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| S100A2 | CXCR5 |
| May function as calcium sensor and modulator,contributing to cellular calcium signaling. May function byinteracting with other proteins, such as TPR-containing proteins,and indirectly play a role in many physiological processes. Mayalso play a role in suppressing tumor cell growth.{ECO:0000269|PubMed:1372446, ECO:0000269|PubMed:22399290}. | Cytokine receptor that binds to B-lymphocytechemoattractant (BLC). Involved in B-cell migration into B-cellfollicles of spleen and Peyer patches but not into those ofmesenteric or peripheral lymph nodes. May have a regulatoryfunction in Burkitt lymphoma (BL) lymphomagenesis and/or B-celldifferentiation. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for S100A2_CXCR5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_S100A2_ENST00000497140_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_431aa KKKKXXVVRQVAALLPQETMRSSFAXICSXRLPPLXRHLAGSLSTXDSDQSGDSQPAQPXTTRXRWKWTSRTWRTCSGNWTDWTTITTPP WWKIISALPQRGPSWPPSRPCSCPWPTASSSSWAXSATSWCWXSWSGTGRHAVPRRPSCSTWPWPTSCWSSSCPLPWPRALWAGSWGPSS AKLXLPCTKSTSTAAACSWPASPWTATWPLSTPSMPTATAASSPSTSPVGPSGWWASSLPCQRFSSPKSAKAITTTPCHVAPSPKRTKQK RMPGSPPDSSTMWRDSCCPCWXWAGATWGXCTGCARPSGALSGRRQSGWPSWXQASSSSAGHPTTSSSSWTPWRGXRPWTIPASXMALSP >In-frame_S100A2_ENST00000368710_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_431aa KKKKXXVVRQVAALLPQETMRSSFAXICSXRLPPLXRHLAGSLSTXDSDQSGDSQPAQPXTTRXRWKWTSRTWRTCSGNWTDWTTITTPP WWKIISALPQRGPSWPPSRPCSCPWPTASSSSWAXSATSWCWXSWSGTGRHAVPRRPSCSTWPWPTSCWSSSCPLPWPRALWAGSWGPSS AKLXLPCTKSTSTAAACSWPASPWTATWPLSTPSMPTATAASSPSTSPVGPSGWWASSLPCQRFSSPKSAKAITTTPCHVAPSPKRTKQK RMPGSPPDSSTMWRDSCCPCWXWAGATWGXCTGCARPSGALSGRRQSGWPSWXQASSSSAGHPTTSSSSWTPWRGXRPWTIPASXMALSP >In-frame_S100A2_ENST00000368707_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_431aa KKKKXXVVRQVAALLPQETMRSSFAXICSXRLPPLXRHLAGSLSTXDSDQSGDSQPAQPXTTRXRWKWTSRTWRTCSGNWTDWTTITTPP WWKIISALPQRGPSWPPSRPCSCPWPTASSSSWAXSATSWCWXSWSGTGRHAVPRRPSCSTWPWPTSCWSSSCPLPWPRALWAGSWGPSS AKLXLPCTKSTSTAAACSWPASPWTATWPLSTPSMPTATAASSPSTSPVGPSGWWASSLPCQRFSSPKSAKAITTTPCHVAPSPKRTKQK RMPGSPPDSSTMWRDSCCPCWXWAGATWGXCTGCARPSGALSGRRQSGWPSWXQASSSSAGHPTTSSSSWTPWRGXRPWTIPASXMALSP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_S100A2_ENST00000497140_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_1295nt AAAAAAAAAAAGTGATGAGTTGTGAGGCAGGTCGCGGCCCTACTGCCTCAGGAGACGATGCGCAGCTCATTTGCTTAAATTTGCAGCTGA CGGCTGCCACCTCTCTAGAGGCACCTGGCGGGGAGCCTCTCAACATAAGACAGTGACCAGTCTGGTGACTCACAGCCGGCACAGCCATGA ACTACCCGCTAACGCTGGAAATGGACCTCGAGAACCTGGAGGACCTGTTCTGGGAACTGGACAGATTGGACAACTATAACGACACCTCCC TGGTGGAAAATCATCTCTGCCCTGCCACAGAGGGGCCCCTCATGGCCTCCTTCAAGGCCGTGTTCGTGCCCGTGGCCTACAGCCTCATCT TCCTCCTGGGCGTGATCGGCAACGTCCTGGTGCTGGTGATCCTGGAGCGGCACCGGCAGACACGCAGTTCCACGGAGACCTTCCTGTTCC ACCTGGCCGTGGCCGACCTCCTGCTGGTCTTCATCTTGCCCTTTGCCGTGGCCGAGGGCTCTGTGGGCTGGGTCCTGGGGACCTTCCTCT GCAAAACTGTGATTGCCCTGCACAAAGTCAACTTCTACTGCAGCAGCCTGCTCCTGGCCTGCATCGCCGTGGACCGCTACCTGGCCATTG TCCACGCCGTCCATGCCTACCGCCACCGCCGCCTCCTCTCCATCCACATCACCTGTGGGACCATCTGGCTGGTGGGCTTCCTCCTTGCCT TGCCAGAGATTCTCTTCGCCAAAGTCAGCCAAGGCCATCACAACAACTCCCTGCCACGTTGCACCTTCTCCCAAGAGAACCAAGCAGAAA CGCATGCCTGGTTCACCTCCCGATTCCTCTACCATGTGGCGGGATTCCTGCTGCCCATGCTGGTGATGGGCTGGTGCTACGTGGGGGTAG TGCACAGGTTGCGCCAGGCCCAGCGGCGCCCTCAGCGGCAGAAGGCAGTCAGGGTGGCCATCCTGGTGACAAGCATCTTCTTCCTCTGCT GGTCACCCTACCACATCGTCATCTTCCTGGACACCCTGGCGAGGCTGAAGGCCGTGGACAATACCTGCAAGCTGAATGGCTCTCTCCCCG TGGCCATCACCATGTGTGAGTTCCTGGGCCTGGCCCACTGCTGCCTCAACCCCATGCTCTACACTTTCGCCGGCGTGAAGTTCCGCAGTG ACCTGTCGCGGCTCCTGACGAAGCTGGGCTGTACCGGCCCTGCCTCCCTGTGCCAGCTCTTCCCTAGCTGGCGCAGGAGCAGTCTCTCTG >In-frame_S100A2_ENST00000368710_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_1295nt AAAAAAAAAAAGTGATGAGTTGTGAGGCAGGTCGCGGCCCTACTGCCTCAGGAGACGATGCGCAGCTCATTTGCTTAAATTTGCAGCTGA CGGCTGCCACCTCTCTAGAGGCACCTGGCGGGGAGCCTCTCAACATAAGACAGTGACCAGTCTGGTGACTCACAGCCGGCACAGCCATGA ACTACCCGCTAACGCTGGAAATGGACCTCGAGAACCTGGAGGACCTGTTCTGGGAACTGGACAGATTGGACAACTATAACGACACCTCCC TGGTGGAAAATCATCTCTGCCCTGCCACAGAGGGGCCCCTCATGGCCTCCTTCAAGGCCGTGTTCGTGCCCGTGGCCTACAGCCTCATCT TCCTCCTGGGCGTGATCGGCAACGTCCTGGTGCTGGTGATCCTGGAGCGGCACCGGCAGACACGCAGTTCCACGGAGACCTTCCTGTTCC ACCTGGCCGTGGCCGACCTCCTGCTGGTCTTCATCTTGCCCTTTGCCGTGGCCGAGGGCTCTGTGGGCTGGGTCCTGGGGACCTTCCTCT GCAAAACTGTGATTGCCCTGCACAAAGTCAACTTCTACTGCAGCAGCCTGCTCCTGGCCTGCATCGCCGTGGACCGCTACCTGGCCATTG TCCACGCCGTCCATGCCTACCGCCACCGCCGCCTCCTCTCCATCCACATCACCTGTGGGACCATCTGGCTGGTGGGCTTCCTCCTTGCCT TGCCAGAGATTCTCTTCGCCAAAGTCAGCCAAGGCCATCACAACAACTCCCTGCCACGTTGCACCTTCTCCCAAGAGAACCAAGCAGAAA CGCATGCCTGGTTCACCTCCCGATTCCTCTACCATGTGGCGGGATTCCTGCTGCCCATGCTGGTGATGGGCTGGTGCTACGTGGGGGTAG TGCACAGGTTGCGCCAGGCCCAGCGGCGCCCTCAGCGGCAGAAGGCAGTCAGGGTGGCCATCCTGGTGACAAGCATCTTCTTCCTCTGCT GGTCACCCTACCACATCGTCATCTTCCTGGACACCCTGGCGAGGCTGAAGGCCGTGGACAATACCTGCAAGCTGAATGGCTCTCTCCCCG TGGCCATCACCATGTGTGAGTTCCTGGGCCTGGCCCACTGCTGCCTCAACCCCATGCTCTACACTTTCGCCGGCGTGAAGTTCCGCAGTG ACCTGTCGCGGCTCCTGACGAAGCTGGGCTGTACCGGCCCTGCCTCCCTGTGCCAGCTCTTCCCTAGCTGGCGCAGGAGCAGTCTCTCTG >In-frame_S100A2_ENST00000368707_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_1295nt AAAAAAAAAAAGTGATGAGTTGTGAGGCAGGTCGCGGCCCTACTGCCTCAGGAGACGATGCGCAGCTCATTTGCTTAAATTTGCAGCTGA CGGCTGCCACCTCTCTAGAGGCACCTGGCGGGGAGCCTCTCAACATAAGACAGTGACCAGTCTGGTGACTCACAGCCGGCACAGCCATGA ACTACCCGCTAACGCTGGAAATGGACCTCGAGAACCTGGAGGACCTGTTCTGGGAACTGGACAGATTGGACAACTATAACGACACCTCCC TGGTGGAAAATCATCTCTGCCCTGCCACAGAGGGGCCCCTCATGGCCTCCTTCAAGGCCGTGTTCGTGCCCGTGGCCTACAGCCTCATCT TCCTCCTGGGCGTGATCGGCAACGTCCTGGTGCTGGTGATCCTGGAGCGGCACCGGCAGACACGCAGTTCCACGGAGACCTTCCTGTTCC ACCTGGCCGTGGCCGACCTCCTGCTGGTCTTCATCTTGCCCTTTGCCGTGGCCGAGGGCTCTGTGGGCTGGGTCCTGGGGACCTTCCTCT GCAAAACTGTGATTGCCCTGCACAAAGTCAACTTCTACTGCAGCAGCCTGCTCCTGGCCTGCATCGCCGTGGACCGCTACCTGGCCATTG TCCACGCCGTCCATGCCTACCGCCACCGCCGCCTCCTCTCCATCCACATCACCTGTGGGACCATCTGGCTGGTGGGCTTCCTCCTTGCCT TGCCAGAGATTCTCTTCGCCAAAGTCAGCCAAGGCCATCACAACAACTCCCTGCCACGTTGCACCTTCTCCCAAGAGAACCAAGCAGAAA CGCATGCCTGGTTCACCTCCCGATTCCTCTACCATGTGGCGGGATTCCTGCTGCCCATGCTGGTGATGGGCTGGTGCTACGTGGGGGTAG TGCACAGGTTGCGCCAGGCCCAGCGGCGCCCTCAGCGGCAGAAGGCAGTCAGGGTGGCCATCCTGGTGACAAGCATCTTCTTCCTCTGCT GGTCACCCTACCACATCGTCATCTTCCTGGACACCCTGGCGAGGCTGAAGGCCGTGGACAATACCTGCAAGCTGAATGGCTCTCTCCCCG TGGCCATCACCATGTGTGAGTTCCTGGGCCTGGCCCACTGCTGCCTCAACCCCATGCTCTACACTTTCGCCGGCGTGAAGTTCCGCAGTG ACCTGTCGCGGCTCCTGACGAAGCTGGGCTGTACCGGCCCTGCCTCCCTGTGCCAGCTCTTCCCTAGCTGGCGCAGGAGCAGTCTCTCTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_S100A2_ENST00000497140_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_5128nt CTCCCCTCACCCCGGTCCAGGATGCCCAGTCCCCACGACACCTCCCACTTCCCACTGTGGCCTGGGTGGGCTCAGGGGCTGCCCTTGACC TGGCCTAGAGCCCTCCCCCAGCTGGTGGTGGAGCTGGCACTCTCTGGGAGGGAGGGGGCTGGGAGGGAATGAGTGGGAATGGCAAGAGGC CAGGGTTTGGTGGGATCAGGTTGAGGCAGGTTTGGTTTCCTTAAAATGCCAAGTTGGGGGCCAGTGGGGCCCACATATAAATCCTCACCC TGGGAGCCTGGCTGCCTTGCTCTCCTTCCTGGGTCTGTCTCTGCCACCTGGTCTGGCGCTGGCTGTGCTGGTCACTACCTTCCACAAGTA CTCCTGCCAAGAGGGCGACAAGTTCAAGCTGAGTAAGGGGGAAATGAAGGAACTTCTGCACAAGGAGCTGCCCAGCTTTGTGGGGGAGAA AGTGGATGAGGAGGGGCTGAAGAAGCTGATGGGCAGCCTGGATGAGAACAGTGACCAGCAGGTGGACTTCCAGGAGTATGCTGTTTTCCT GGCACTCATCACTGTCATGTGCAATGACTTCTTCCAGGGCTGCCCAGACCGACCCTGAAGCAGAACTCTTGACTTCCTGCCATGGATCTC TTGGGCCCAGGACTGTTGATGCCTTTGAGTTTTGTATTCAATAAACTTTTTTTGTCTGTTGATAATAAAAAAAAAAAAGTGATGAGTTGT GAGGCAGGTCGCGGCCCTACTGCCTCAGGAGACGATGCGCAGCTCATTTGCTTAAATTTGCAGCTGACGGCTGCCACCTCTCTAGAGGCA CCTGGCGGGGAGCCTCTCAACATAAGACAGTGACCAGTCTGGTGACTCACAGCCGGCACAGCCATGAACTACCCGCTAACGCTGGAAATG GACCTCGAGAACCTGGAGGACCTGTTCTGGGAACTGGACAGATTGGACAACTATAACGACACCTCCCTGGTGGAAAATCATCTCTGCCCT GCCACAGAGGGGCCCCTCATGGCCTCCTTCAAGGCCGTGTTCGTGCCCGTGGCCTACAGCCTCATCTTCCTCCTGGGCGTGATCGGCAAC GTCCTGGTGCTGGTGATCCTGGAGCGGCACCGGCAGACACGCAGTTCCACGGAGACCTTCCTGTTCCACCTGGCCGTGGCCGACCTCCTG CTGGTCTTCATCTTGCCCTTTGCCGTGGCCGAGGGCTCTGTGGGCTGGGTCCTGGGGACCTTCCTCTGCAAAACTGTGATTGCCCTGCAC AAAGTCAACTTCTACTGCAGCAGCCTGCTCCTGGCCTGCATCGCCGTGGACCGCTACCTGGCCATTGTCCACGCCGTCCATGCCTACCGC CACCGCCGCCTCCTCTCCATCCACATCACCTGTGGGACCATCTGGCTGGTGGGCTTCCTCCTTGCCTTGCCAGAGATTCTCTTCGCCAAA GTCAGCCAAGGCCATCACAACAACTCCCTGCCACGTTGCACCTTCTCCCAAGAGAACCAAGCAGAAACGCATGCCTGGTTCACCTCCCGA TTCCTCTACCATGTGGCGGGATTCCTGCTGCCCATGCTGGTGATGGGCTGGTGCTACGTGGGGGTAGTGCACAGGTTGCGCCAGGCCCAG CGGCGCCCTCAGCGGCAGAAGGCAGTCAGGGTGGCCATCCTGGTGACAAGCATCTTCTTCCTCTGCTGGTCACCCTACCACATCGTCATC TTCCTGGACACCCTGGCGAGGCTGAAGGCCGTGGACAATACCTGCAAGCTGAATGGCTCTCTCCCCGTGGCCATCACCATGTGTGAGTTC CTGGGCCTGGCCCACTGCTGCCTCAACCCCATGCTCTACACTTTCGCCGGCGTGAAGTTCCGCAGTGACCTGTCGCGGCTCCTGACGAAG CTGGGCTGTACCGGCCCTGCCTCCCTGTGCCAGCTCTTCCCTAGCTGGCGCAGGAGCAGTCTCTCTGAGTCAGAGAATGCCACCTCTCTC ACCACGTTCTAGGTCCCAGTGTCCCCTTTTATTGCTGCTTTTCCTTGGGGCAGGCAGTGATGCTGGATGCTCCTTCCAACAGGAGCTGGG ATCCTAAGGGCTCACCGTGGCTAAGAGTGTCCTAGGAGTATCCTCATTTGGGGTAGCTAGAGGAACCAACCCCCATTTCTAGAACATCCC TGCCAGCTCTTCTGCCGGCCCTGGGGCTAGGCTGGAGCCCAGGGAGCGGAAAGCAGCTCAAAGGCACAGTGAAGGCTGTCCTTACCCATC TGCACCCCCCTGGGCTGAGAGAACCTCACGCACCTCCCATCCTAATCATCCAATGCTCAAGAAACAACTTCTACTTCTGCCCTTGCCAAC GGAGAGCGCCTGCCCCTCCCAGAACACACTCCATCAGCTTAGGGGCTGCTGACCTCCACAGCTTCCCCTCTCTCCTCCTGCCCACCTGTC AAACAAAGCCAGAAGCTGAGCACCAGGGGATGAGTGGAGGTTAAGGCTGAGGAAAGGCCAGCTGGCAGCAGAGTGTGGCCTTCGGACAAC TCAGTCCCTAAAAACACAGACATTCTGCCAGGCCCCCAAGCCTGCAGTCATCTTGACCAAGCAGGAAGCTCAGACTGGTTGAGTTCAGGT AGCTGCCCCTGGCTCTGACCGAAACAGCGCTGGGTCCACCCCATGTCACCGGATCCTGGGTGGTCTGCAGGCAGGGCTGACTCTAGGTGC CCTTGGAGGCCAGCCAGTGACCTGAGGAAGCGTGAAGGCCGAGAAGCAAGAAAGAAACCCGACAGAGGGAAGAAAAGAGCTTTCTTCCCG AACCCCAAGGAGGGAGATGGATCAATCAAACCCGGCGGTCCCCTCCGCCAGGCGAGATGGGGTGGGGTGGAGAACTCCTAGGGTGGCTGG GTCCAGGGGATGGGAGGTTGTGGGCATTGATGGGGAAGGAGGCTGGCTTGTCCCCTCCTCACTCCCTTCCCATAAGCTATAGACCCGAGG AAACTCAGAGTCGGAACGGAGAAAGGTGGACTGGAAGGGGCCCGTGGGAGTCATCTCAACCATCCCCTCCGTGGCATCACCTTAGGCAGG GAAGTGTAAGAAACACACTGAGGCAGGGAAGTCCCCAGGCCCCAGGAAGCCGTGCCCTGCCCCCGTGAGGATGTCACTCAGATGGAACCG CAGGAAGCTGCTCCGTGCTTGTTTGCTCACCTGGGGTGTGGGAGGCCCGTCCGGCAGTTCTGGGTGCTCCCTACCACCTCCCCAGCCTTT GATCAGGTGGGGAGTCAGGGACCCCTGCCCTTGTCCCACTCAAGCCAAGCAGCCAAGCTCCTTGGGAGGCCCCACTGGGGAAATAACAGC TGTGGCTCACGTGAGAGTGTCTTCACGGCAGGACAACGAGGAAGCCCTAAGACGTCCCTTTTTTCTCTGAGTATCTCCTCGCAAGCTGGG TAATCGATGGGGGAGTCTGAAGCAGATGCAAAGAGGCAAGAGGCTGGATTTTGAATTTTCTTTTTAATAAAAAGGCACCTATAAAACAGG TCAATACAGTACAGGCAGCACAGAGACCCCCGGAACAAGCCTAAAAATTGTTTCAAAATAAAAACCAAGAAGATGTCTTCACATATTGTA TTTATATATTTATATTTATATATATATTTATATAATGGTACAAAATGGCTGGGGGTGTGGCCATGGATGGAGGGAAGAGTAGGCTGGCCT GTGGCGTGGGTGGGAGGAGAGGGGACGGAGAGGGCACTCGGCCCGCTGCAATCTGACCCCTCTCTCCTCAGGGCAGGAAACACAGAGTCA GACAGTTTGGGGGGGTCTTGGGCCAGGGGTGGAGGGCTCAAGGGCACAGGGCCCAGGCTGAGGCAGGGCGGGCAAAGCGCCTGGCAGGAT GAAGGGCAAGTGGCCCCCCAAACACAGAGGCCCTGGCCATGGACCCTGGGAGGTGACCGGGGTGAGTCAGGGGCCTGTTGTCAGCCCCAG AGGAAGCGCTGGACCTGGCCGATGGTGGGCCGAGAGGACAGCACCAGGCTGGGAGAAGTGGGGCGAGTTCCCTTTGTATTACAGCTGCCA GTGCAAGACCAGGCCCTCCAGGCCAGGAAGGCTAGGGACGGGTCCTGGTAGAAGACACCCTGTCTAGAATGGCCCTTGGTCCTGGAGGTG GGGCGCAAAAGGCCTCAGCCAGGGAACTGCCCTGCCACCTCCCGAGGCAGGAAAGGAAGTGAGAAAAGGAGAAGTTTTTTTACTCCTGGG GCCAAAGTAGGGGGACAAACACCCAGTCGTATATGGCTTCAGCTCTGACCAAAGGCGGATAGGGAGCTCTCCTGGGTAGGAGCAGGGAGC CAAGGGGGAGGCAGTGGCTGTGCCTGGGTGGGCACAGACAGATCTGGTACATGGCCCTGAGCCCTGGGCAGAGGGACAACCTTGCCGGTG AGTGGGCAGGCAGAGAGGAGGCGGCAGGATGCTGTTTCCCCGATTCCATCCTCAGGGAGTGGAGACTGGAGGGGAGGTGCACTGACTCAG ATGAACTGTTCTCCCCCTTCTTTGATAAGAAGTAGGTGGCAGCAGCCTCTGGAAAAGTCAGGGCCCTGGAGGTTACCTGGCCCAGGGCTA CTACAGCCACAGGCCCCAGTGGCACCATGCCACCCCTTCCATGGCTCCACTCAAGGGGGCCACACAGCCACCGCCTCTTCCTCCTTTCCT TCATCCCAAACTGGGACAAAAGACTTCAAGTTCTGGCTAAGATGTAGCAGCAGCGGATGCCCGGGCATCCAAAGTGGAAAGCCAGGGCCC CGTGTCACCGGTGTGGGCAAACACACATGCACGTGCACACATGTTCTCCCTGAATCACTCAGCAGCAGACAGGCTGCCGCCCTGGGGGTC TCAGCCCTGCTAGGGCTCACCAGGTGGAAGCCTAGGTGGTCTGACCTCAGTTTAGGAGTGGGTCATTTACGTCATCTTACCATTTGGGGA CGAGACAGGAATGGTATCCCTTAGGGACCCAGAGACACTGCAAACAGTGGGTGGCCATGTAGGGCTGCATGTCCCTGGGTCCAGGGGAAT >In-frame_S100A2_ENST00000368710_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_4884nt GTGAGCTCACCATGTGGGGGTGAGGCTGAGAGAAAACAAGTACACAGCCACAGATCCATGATGTGCAGTTCTCTGGAGCAGGCGCTGGCT GTGCTGGTCACTACCTTCCACAAGTACTCCTGCCAAGAGGGCGACAAGTTCAAGCTGAGTAAGGGGGAAATGAAGGAACTTCTGCACAAG GAGCTGCCCAGCTTTGTGGGGGAGAAAGTGGATGAGGAGGGGCTGAAGAAGCTGATGGGCAGCCTGGATGAGAACAGTGACCAGCAGGTG GACTTCCAGGAGTATGCTGTTTTCCTGGCACTCATCACTGTCATGTGCAATGACTTCTTCCAGGGCTGCCCAGACCGACCCTGAAGCAGA ACTCTTGACTTCCTGCCATGGATCTCTTGGGCCCAGGACTGTTGATGCCTTTGAGTTTTGTATTCAATAAACTTTTTTTGTCTGTTGATA ATAAAAAAAAAAAAGTGATGAGTTGTGAGGCAGGTCGCGGCCCTACTGCCTCAGGAGACGATGCGCAGCTCATTTGCTTAAATTTGCAGC TGACGGCTGCCACCTCTCTAGAGGCACCTGGCGGGGAGCCTCTCAACATAAGACAGTGACCAGTCTGGTGACTCACAGCCGGCACAGCCA TGAACTACCCGCTAACGCTGGAAATGGACCTCGAGAACCTGGAGGACCTGTTCTGGGAACTGGACAGATTGGACAACTATAACGACACCT CCCTGGTGGAAAATCATCTCTGCCCTGCCACAGAGGGGCCCCTCATGGCCTCCTTCAAGGCCGTGTTCGTGCCCGTGGCCTACAGCCTCA TCTTCCTCCTGGGCGTGATCGGCAACGTCCTGGTGCTGGTGATCCTGGAGCGGCACCGGCAGACACGCAGTTCCACGGAGACCTTCCTGT TCCACCTGGCCGTGGCCGACCTCCTGCTGGTCTTCATCTTGCCCTTTGCCGTGGCCGAGGGCTCTGTGGGCTGGGTCCTGGGGACCTTCC TCTGCAAAACTGTGATTGCCCTGCACAAAGTCAACTTCTACTGCAGCAGCCTGCTCCTGGCCTGCATCGCCGTGGACCGCTACCTGGCCA TTGTCCACGCCGTCCATGCCTACCGCCACCGCCGCCTCCTCTCCATCCACATCACCTGTGGGACCATCTGGCTGGTGGGCTTCCTCCTTG CCTTGCCAGAGATTCTCTTCGCCAAAGTCAGCCAAGGCCATCACAACAACTCCCTGCCACGTTGCACCTTCTCCCAAGAGAACCAAGCAG AAACGCATGCCTGGTTCACCTCCCGATTCCTCTACCATGTGGCGGGATTCCTGCTGCCCATGCTGGTGATGGGCTGGTGCTACGTGGGGG TAGTGCACAGGTTGCGCCAGGCCCAGCGGCGCCCTCAGCGGCAGAAGGCAGTCAGGGTGGCCATCCTGGTGACAAGCATCTTCTTCCTCT GCTGGTCACCCTACCACATCGTCATCTTCCTGGACACCCTGGCGAGGCTGAAGGCCGTGGACAATACCTGCAAGCTGAATGGCTCTCTCC CCGTGGCCATCACCATGTGTGAGTTCCTGGGCCTGGCCCACTGCTGCCTCAACCCCATGCTCTACACTTTCGCCGGCGTGAAGTTCCGCA GTGACCTGTCGCGGCTCCTGACGAAGCTGGGCTGTACCGGCCCTGCCTCCCTGTGCCAGCTCTTCCCTAGCTGGCGCAGGAGCAGTCTCT CTGAGTCAGAGAATGCCACCTCTCTCACCACGTTCTAGGTCCCAGTGTCCCCTTTTATTGCTGCTTTTCCTTGGGGCAGGCAGTGATGCT GGATGCTCCTTCCAACAGGAGCTGGGATCCTAAGGGCTCACCGTGGCTAAGAGTGTCCTAGGAGTATCCTCATTTGGGGTAGCTAGAGGA ACCAACCCCCATTTCTAGAACATCCCTGCCAGCTCTTCTGCCGGCCCTGGGGCTAGGCTGGAGCCCAGGGAGCGGAAAGCAGCTCAAAGG CACAGTGAAGGCTGTCCTTACCCATCTGCACCCCCCTGGGCTGAGAGAACCTCACGCACCTCCCATCCTAATCATCCAATGCTCAAGAAA CAACTTCTACTTCTGCCCTTGCCAACGGAGAGCGCCTGCCCCTCCCAGAACACACTCCATCAGCTTAGGGGCTGCTGACCTCCACAGCTT CCCCTCTCTCCTCCTGCCCACCTGTCAAACAAAGCCAGAAGCTGAGCACCAGGGGATGAGTGGAGGTTAAGGCTGAGGAAAGGCCAGCTG GCAGCAGAGTGTGGCCTTCGGACAACTCAGTCCCTAAAAACACAGACATTCTGCCAGGCCCCCAAGCCTGCAGTCATCTTGACCAAGCAG GAAGCTCAGACTGGTTGAGTTCAGGTAGCTGCCCCTGGCTCTGACCGAAACAGCGCTGGGTCCACCCCATGTCACCGGATCCTGGGTGGT CTGCAGGCAGGGCTGACTCTAGGTGCCCTTGGAGGCCAGCCAGTGACCTGAGGAAGCGTGAAGGCCGAGAAGCAAGAAAGAAACCCGACA GAGGGAAGAAAAGAGCTTTCTTCCCGAACCCCAAGGAGGGAGATGGATCAATCAAACCCGGCGGTCCCCTCCGCCAGGCGAGATGGGGTG GGGTGGAGAACTCCTAGGGTGGCTGGGTCCAGGGGATGGGAGGTTGTGGGCATTGATGGGGAAGGAGGCTGGCTTGTCCCCTCCTCACTC CCTTCCCATAAGCTATAGACCCGAGGAAACTCAGAGTCGGAACGGAGAAAGGTGGACTGGAAGGGGCCCGTGGGAGTCATCTCAACCATC CCCTCCGTGGCATCACCTTAGGCAGGGAAGTGTAAGAAACACACTGAGGCAGGGAAGTCCCCAGGCCCCAGGAAGCCGTGCCCTGCCCCC GTGAGGATGTCACTCAGATGGAACCGCAGGAAGCTGCTCCGTGCTTGTTTGCTCACCTGGGGTGTGGGAGGCCCGTCCGGCAGTTCTGGG TGCTCCCTACCACCTCCCCAGCCTTTGATCAGGTGGGGAGTCAGGGACCCCTGCCCTTGTCCCACTCAAGCCAAGCAGCCAAGCTCCTTG GGAGGCCCCACTGGGGAAATAACAGCTGTGGCTCACGTGAGAGTGTCTTCACGGCAGGACAACGAGGAAGCCCTAAGACGTCCCTTTTTT CTCTGAGTATCTCCTCGCAAGCTGGGTAATCGATGGGGGAGTCTGAAGCAGATGCAAAGAGGCAAGAGGCTGGATTTTGAATTTTCTTTT TAATAAAAAGGCACCTATAAAACAGGTCAATACAGTACAGGCAGCACAGAGACCCCCGGAACAAGCCTAAAAATTGTTTCAAAATAAAAA CCAAGAAGATGTCTTCACATATTGTATTTATATATTTATATTTATATATATATTTATATAATGGTACAAAATGGCTGGGGGTGTGGCCAT GGATGGAGGGAAGAGTAGGCTGGCCTGTGGCGTGGGTGGGAGGAGAGGGGACGGAGAGGGCACTCGGCCCGCTGCAATCTGACCCCTCTC TCCTCAGGGCAGGAAACACAGAGTCAGACAGTTTGGGGGGGTCTTGGGCCAGGGGTGGAGGGCTCAAGGGCACAGGGCCCAGGCTGAGGC AGGGCGGGCAAAGCGCCTGGCAGGATGAAGGGCAAGTGGCCCCCCAAACACAGAGGCCCTGGCCATGGACCCTGGGAGGTGACCGGGGTG AGTCAGGGGCCTGTTGTCAGCCCCAGAGGAAGCGCTGGACCTGGCCGATGGTGGGCCGAGAGGACAGCACCAGGCTGGGAGAAGTGGGGC GAGTTCCCTTTGTATTACAGCTGCCAGTGCAAGACCAGGCCCTCCAGGCCAGGAAGGCTAGGGACGGGTCCTGGTAGAAGACACCCTGTC TAGAATGGCCCTTGGTCCTGGAGGTGGGGCGCAAAAGGCCTCAGCCAGGGAACTGCCCTGCCACCTCCCGAGGCAGGAAAGGAAGTGAGA AAAGGAGAAGTTTTTTTACTCCTGGGGCCAAAGTAGGGGGACAAACACCCAGTCGTATATGGCTTCAGCTCTGACCAAAGGCGGATAGGG AGCTCTCCTGGGTAGGAGCAGGGAGCCAAGGGGGAGGCAGTGGCTGTGCCTGGGTGGGCACAGACAGATCTGGTACATGGCCCTGAGCCC TGGGCAGAGGGACAACCTTGCCGGTGAGTGGGCAGGCAGAGAGGAGGCGGCAGGATGCTGTTTCCCCGATTCCATCCTCAGGGAGTGGAG ACTGGAGGGGAGGTGCACTGACTCAGATGAACTGTTCTCCCCCTTCTTTGATAAGAAGTAGGTGGCAGCAGCCTCTGGAAAAGTCAGGGC CCTGGAGGTTACCTGGCCCAGGGCTACTACAGCCACAGGCCCCAGTGGCACCATGCCACCCCTTCCATGGCTCCACTCAAGGGGGCCACA CAGCCACCGCCTCTTCCTCCTTTCCTTCATCCCAAACTGGGACAAAAGACTTCAAGTTCTGGCTAAGATGTAGCAGCAGCGGATGCCCGG GCATCCAAAGTGGAAAGCCAGGGCCCCGTGTCACCGGTGTGGGCAAACACACATGCACGTGCACACATGTTCTCCCTGAATCACTCAGCA GCAGACAGGCTGCCGCCCTGGGGGTCTCAGCCCTGCTAGGGCTCACCAGGTGGAAGCCTAGGTGGTCTGACCTCAGTTTAGGAGTGGGTC ATTTACGTCATCTTACCATTTGGGGACGAGACAGGAATGGTATCCCTTAGGGACCCAGAGACACTGCAAACAGTGGGTGGCCATGTAGGG CTGCATGTCCCTGGGTCCAGGGGAATGGAGGGAGCAATAACTTGAAGAAGGGGGGAAGGGTTTCTTTTATCCTTTTTTTTTTGTGTGACT >In-frame_S100A2_ENST00000368707_chr1_153533819_-_CXCR5_ENST00000292174_chr11_118754475_+_4987nt GCTCTCCTTCCTGGGTCTGTCTCTGCCACCTGGTCTGCCACAGATCCATGATGTGCAGTTCTCTGGAGCAGGCGCTGGCTGTGCTGGTCA CTACCTTCCACAAGTACTCCTGCCAAGAGGGCGACAAGTTCAAGCTGAGTAAGGGGGAAATGAAGGAACTTCTGCACAAGGAGCTGCCCA GCTTTGTGGGGCATTCCAGAGAACCATGTGCTGTGAGGGCCTTCCGAGTCCATCTGTTTAATCCTGTCATTGGAGACTTGAGAAACCAGA GCCCAGAAGGGAAAAGTGATTGTCCCAAGATCACACAGCACTGGAGAAAGTGGATGAGGAGGGGCTGAAGAAGCTGATGGGCAGCCTGGA TGAGAACAGTGACCAGCAGGTGGACTTCCAGGAGTATGCTGTTTTCCTGGCACTCATCACTGTCATGTGCAATGACTTCTTCCAGGGCTG CCCAGACCGACCCTGAAGCAGAACTCTTGACTTCCTGCCATGGATCTCTTGGGCCCAGGACTGTTGATGCCTTTGAGTTTTGTATTCAAT AAACTTTTTTTGTCTGAAAAAAAAAAAGTGATGAGTTGTGAGGCAGGTCGCGGCCCTACTGCCTCAGGAGACGATGCGCAGCTCATTTGC TTAAATTTGCAGCTGACGGCTGCCACCTCTCTAGAGGCACCTGGCGGGGAGCCTCTCAACATAAGACAGTGACCAGTCTGGTGACTCACA GCCGGCACAGCCATGAACTACCCGCTAACGCTGGAAATGGACCTCGAGAACCTGGAGGACCTGTTCTGGGAACTGGACAGATTGGACAAC TATAACGACACCTCCCTGGTGGAAAATCATCTCTGCCCTGCCACAGAGGGGCCCCTCATGGCCTCCTTCAAGGCCGTGTTCGTGCCCGTG GCCTACAGCCTCATCTTCCTCCTGGGCGTGATCGGCAACGTCCTGGTGCTGGTGATCCTGGAGCGGCACCGGCAGACACGCAGTTCCACG GAGACCTTCCTGTTCCACCTGGCCGTGGCCGACCTCCTGCTGGTCTTCATCTTGCCCTTTGCCGTGGCCGAGGGCTCTGTGGGCTGGGTC CTGGGGACCTTCCTCTGCAAAACTGTGATTGCCCTGCACAAAGTCAACTTCTACTGCAGCAGCCTGCTCCTGGCCTGCATCGCCGTGGAC CGCTACCTGGCCATTGTCCACGCCGTCCATGCCTACCGCCACCGCCGCCTCCTCTCCATCCACATCACCTGTGGGACCATCTGGCTGGTG GGCTTCCTCCTTGCCTTGCCAGAGATTCTCTTCGCCAAAGTCAGCCAAGGCCATCACAACAACTCCCTGCCACGTTGCACCTTCTCCCAA GAGAACCAAGCAGAAACGCATGCCTGGTTCACCTCCCGATTCCTCTACCATGTGGCGGGATTCCTGCTGCCCATGCTGGTGATGGGCTGG TGCTACGTGGGGGTAGTGCACAGGTTGCGCCAGGCCCAGCGGCGCCCTCAGCGGCAGAAGGCAGTCAGGGTGGCCATCCTGGTGACAAGC ATCTTCTTCCTCTGCTGGTCACCCTACCACATCGTCATCTTCCTGGACACCCTGGCGAGGCTGAAGGCCGTGGACAATACCTGCAAGCTG AATGGCTCTCTCCCCGTGGCCATCACCATGTGTGAGTTCCTGGGCCTGGCCCACTGCTGCCTCAACCCCATGCTCTACACTTTCGCCGGC GTGAAGTTCCGCAGTGACCTGTCGCGGCTCCTGACGAAGCTGGGCTGTACCGGCCCTGCCTCCCTGTGCCAGCTCTTCCCTAGCTGGCGC AGGAGCAGTCTCTCTGAGTCAGAGAATGCCACCTCTCTCACCACGTTCTAGGTCCCAGTGTCCCCTTTTATTGCTGCTTTTCCTTGGGGC AGGCAGTGATGCTGGATGCTCCTTCCAACAGGAGCTGGGATCCTAAGGGCTCACCGTGGCTAAGAGTGTCCTAGGAGTATCCTCATTTGG GGTAGCTAGAGGAACCAACCCCCATTTCTAGAACATCCCTGCCAGCTCTTCTGCCGGCCCTGGGGCTAGGCTGGAGCCCAGGGAGCGGAA AGCAGCTCAAAGGCACAGTGAAGGCTGTCCTTACCCATCTGCACCCCCCTGGGCTGAGAGAACCTCACGCACCTCCCATCCTAATCATCC AATGCTCAAGAAACAACTTCTACTTCTGCCCTTGCCAACGGAGAGCGCCTGCCCCTCCCAGAACACACTCCATCAGCTTAGGGGCTGCTG ACCTCCACAGCTTCCCCTCTCTCCTCCTGCCCACCTGTCAAACAAAGCCAGAAGCTGAGCACCAGGGGATGAGTGGAGGTTAAGGCTGAG GAAAGGCCAGCTGGCAGCAGAGTGTGGCCTTCGGACAACTCAGTCCCTAAAAACACAGACATTCTGCCAGGCCCCCAAGCCTGCAGTCAT CTTGACCAAGCAGGAAGCTCAGACTGGTTGAGTTCAGGTAGCTGCCCCTGGCTCTGACCGAAACAGCGCTGGGTCCACCCCATGTCACCG GATCCTGGGTGGTCTGCAGGCAGGGCTGACTCTAGGTGCCCTTGGAGGCCAGCCAGTGACCTGAGGAAGCGTGAAGGCCGAGAAGCAAGA AAGAAACCCGACAGAGGGAAGAAAAGAGCTTTCTTCCCGAACCCCAAGGAGGGAGATGGATCAATCAAACCCGGCGGTCCCCTCCGCCAG GCGAGATGGGGTGGGGTGGAGAACTCCTAGGGTGGCTGGGTCCAGGGGATGGGAGGTTGTGGGCATTGATGGGGAAGGAGGCTGGCTTGT CCCCTCCTCACTCCCTTCCCATAAGCTATAGACCCGAGGAAACTCAGAGTCGGAACGGAGAAAGGTGGACTGGAAGGGGCCCGTGGGAGT CATCTCAACCATCCCCTCCGTGGCATCACCTTAGGCAGGGAAGTGTAAGAAACACACTGAGGCAGGGAAGTCCCCAGGCCCCAGGAAGCC GTGCCCTGCCCCCGTGAGGATGTCACTCAGATGGAACCGCAGGAAGCTGCTCCGTGCTTGTTTGCTCACCTGGGGTGTGGGAGGCCCGTC CGGCAGTTCTGGGTGCTCCCTACCACCTCCCCAGCCTTTGATCAGGTGGGGAGTCAGGGACCCCTGCCCTTGTCCCACTCAAGCCAAGCA GCCAAGCTCCTTGGGAGGCCCCACTGGGGAAATAACAGCTGTGGCTCACGTGAGAGTGTCTTCACGGCAGGACAACGAGGAAGCCCTAAG ACGTCCCTTTTTTCTCTGAGTATCTCCTCGCAAGCTGGGTAATCGATGGGGGAGTCTGAAGCAGATGCAAAGAGGCAAGAGGCTGGATTT TGAATTTTCTTTTTAATAAAAAGGCACCTATAAAACAGGTCAATACAGTACAGGCAGCACAGAGACCCCCGGAACAAGCCTAAAAATTGT TTCAAAATAAAAACCAAGAAGATGTCTTCACATATTGTATTTATATATTTATATTTATATATATATTTATATAATGGTACAAAATGGCTG GGGGTGTGGCCATGGATGGAGGGAAGAGTAGGCTGGCCTGTGGCGTGGGTGGGAGGAGAGGGGACGGAGAGGGCACTCGGCCCGCTGCAA TCTGACCCCTCTCTCCTCAGGGCAGGAAACACAGAGTCAGACAGTTTGGGGGGGTCTTGGGCCAGGGGTGGAGGGCTCAAGGGCACAGGG CCCAGGCTGAGGCAGGGCGGGCAAAGCGCCTGGCAGGATGAAGGGCAAGTGGCCCCCCAAACACAGAGGCCCTGGCCATGGACCCTGGGA GGTGACCGGGGTGAGTCAGGGGCCTGTTGTCAGCCCCAGAGGAAGCGCTGGACCTGGCCGATGGTGGGCCGAGAGGACAGCACCAGGCTG GGAGAAGTGGGGCGAGTTCCCTTTGTATTACAGCTGCCAGTGCAAGACCAGGCCCTCCAGGCCAGGAAGGCTAGGGACGGGTCCTGGTAG AAGACACCCTGTCTAGAATGGCCCTTGGTCCTGGAGGTGGGGCGCAAAAGGCCTCAGCCAGGGAACTGCCCTGCCACCTCCCGAGGCAGG AAAGGAAGTGAGAAAAGGAGAAGTTTTTTTACTCCTGGGGCCAAAGTAGGGGGACAAACACCCAGTCGTATATGGCTTCAGCTCTGACCA AAGGCGGATAGGGAGCTCTCCTGGGTAGGAGCAGGGAGCCAAGGGGGAGGCAGTGGCTGTGCCTGGGTGGGCACAGACAGATCTGGTACA TGGCCCTGAGCCCTGGGCAGAGGGACAACCTTGCCGGTGAGTGGGCAGGCAGAGAGGAGGCGGCAGGATGCTGTTTCCCCGATTCCATCC TCAGGGAGTGGAGACTGGAGGGGAGGTGCACTGACTCAGATGAACTGTTCTCCCCCTTCTTTGATAAGAAGTAGGTGGCAGCAGCCTCTG GAAAAGTCAGGGCCCTGGAGGTTACCTGGCCCAGGGCTACTACAGCCACAGGCCCCAGTGGCACCATGCCACCCCTTCCATGGCTCCACT CAAGGGGGCCACACAGCCACCGCCTCTTCCTCCTTTCCTTCATCCCAAACTGGGACAAAAGACTTCAAGTTCTGGCTAAGATGTAGCAGC AGCGGATGCCCGGGCATCCAAAGTGGAAAGCCAGGGCCCCGTGTCACCGGTGTGGGCAAACACACATGCACGTGCACACATGTTCTCCCT GAATCACTCAGCAGCAGACAGGCTGCCGCCCTGGGGGTCTCAGCCCTGCTAGGGCTCACCAGGTGGAAGCCTAGGTGGTCTGACCTCAGT TTAGGAGTGGGTCATTTACGTCATCTTACCATTTGGGGACGAGACAGGAATGGTATCCCTTAGGGACCCAGAGACACTGCAAACAGTGGG TGGCCATGTAGGGCTGCATGTCCCTGGGTCCAGGGGAATGGAGGGAGCAATAACTTGAAGAAGGGGGGAAGGGTTTCTTTTATCCTTTTT |
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FusionGenePPI for S100A2_CXCR5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| S100A2 | S100A2, MDM2, STUB1, ATF2, PPID, FKBP4, S100A1, S100B, HOPX, C17orf105, FOXP2, GMCL1, FAM60A | CXCR5 | CXCR4, GNB3, GNG8, GNAI2, GNA11, GNA13 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for S100A2_CXCR5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | S100A2 | P29034 | DB00768 | Olopatadine | Protein S100-A2 | small molecule | approved |
| Hgene | S100A2 | P29034 | DB01593 | Zinc | Protein S100-A2 | small molecule | approved|investigational |
| Hgene | S100A2 | P29034 | DB01373 | Calcium | Protein S100-A2 | small molecule | approved|nutraceutical |
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RelatedDiseases for S100A2_CXCR5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CXCR5 | C0023892 | Biliary cirrhosis | 1 | CTD_human |
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