|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 32317 |
FusionGeneSummary for RSU1_FANCI |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RSU1_FANCI | Fusion gene ID: 32317 | Hgene | Tgene | Gene symbol | RSU1 | FANCI | Gene ID | 6251 | 55215 |
| Gene name | Ras suppressor protein 1 | FA complementation group I | |
| Synonyms | RSP-1 | KIAA1794 | |
| Cytomap | 10p13 | 15q26.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras suppressor protein 1ras suppressor protein 1 variant 1ras suppressor protein 1 variant 2ras suppressor protein 1 variant 3ras suppressor protein 1 variant 5rsu-1 | Fanconi anemia group I proteinFanconi anemia complementation group I | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q15404 | Q9NVI1 | |
| Ensembl transtripts involved in fusion gene | ENST00000377921, ENST00000345264, ENST00000602389, ENST00000464074, | ENST00000300027, ENST00000310775, ENST00000451393, ENST00000567996, ENST00000566615, | |
| Fusion gene scores | * DoF score | 6 X 4 X 6=144 | 2 X 2 X 2=8 |
| # samples | 6 | 2 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: RSU1 [Title/Abstract] AND FANCI [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FANCI | GO:0031398 | positive regulation of protein ubiquitination | 18029348 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A1L4-01A | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000377921 | ENST00000300027 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| In-frame | ENST00000377921 | ENST00000310775 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| 5CDS-intron | ENST00000377921 | ENST00000451393 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| 5CDS-intron | ENST00000377921 | ENST00000567996 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| 5CDS-intron | ENST00000377921 | ENST00000566615 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| Frame-shift | ENST00000345264 | ENST00000300027 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| Frame-shift | ENST00000345264 | ENST00000310775 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| 5CDS-intron | ENST00000345264 | ENST00000451393 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| 5CDS-intron | ENST00000345264 | ENST00000567996 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| 5CDS-intron | ENST00000345264 | ENST00000566615 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-3CDS | ENST00000602389 | ENST00000300027 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-3CDS | ENST00000602389 | ENST00000310775 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-intron | ENST00000602389 | ENST00000451393 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-intron | ENST00000602389 | ENST00000567996 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-intron | ENST00000602389 | ENST00000566615 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-3CDS | ENST00000464074 | ENST00000300027 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-3CDS | ENST00000464074 | ENST00000310775 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-intron | ENST00000464074 | ENST00000451393 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-intron | ENST00000464074 | ENST00000567996 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
| intron-intron | ENST00000464074 | ENST00000566615 | RSU1 | chr10 | 16858972 | - | FANCI | chr15 | 89816608 | + |
Top |
FusionProtFeatures for RSU1_FANCI |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RSU1 | FANCI |
| Potentially plays a role in the Ras signal transductionpathway. Capable of suppressing v-Ras transformation in vitro. | Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair ofinterstrand DNA cross-links (ICLs) by promoting FANCD2monoubiquitination by FANCL and participating in recruitment toDNA repair sites. Required for maintenance of chromosomalstability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participatesin S phase and G2 phase checkpoint activation upon DNA damage.{ECO:0000269|PubMed:17412408, ECO:0000269|PubMed:17452773,ECO:0000269|PubMed:17460694, ECO:0000269|PubMed:19111657}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000345264 | - | 2 | 9 | 110_133 | 36 | 278 | Repeat | Note=LRR 4 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000345264 | - | 2 | 9 | 135_156 | 36 | 278 | Repeat | Note=LRR 5 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000345264 | - | 2 | 9 | 158_179 | 36 | 278 | Repeat | Note=LRR 6 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000345264 | - | 2 | 9 | 181_202 | 36 | 278 | Repeat | Note=LRR 7 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000345264 | - | 2 | 9 | 41_63 | 36 | 278 | Repeat | Note=LRR 1 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000345264 | - | 2 | 9 | 64_85 | 36 | 278 | Repeat | Note=LRR 2 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000345264 | - | 2 | 9 | 87_109 | 36 | 278 | Repeat | Note=LRR 3 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000377921 | - | 1 | 8 | 110_133 | 36 | 278 | Repeat | Note=LRR 4 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000377921 | - | 1 | 8 | 135_156 | 36 | 278 | Repeat | Note=LRR 5 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000377921 | - | 1 | 8 | 158_179 | 36 | 278 | Repeat | Note=LRR 6 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000377921 | - | 1 | 8 | 181_202 | 36 | 278 | Repeat | Note=LRR 7 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000377921 | - | 1 | 8 | 41_63 | 36 | 278 | Repeat | Note=LRR 1 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000377921 | - | 1 | 8 | 64_85 | 36 | 278 | Repeat | Note=LRR 2 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000377921 | - | 1 | 8 | 87_109 | 36 | 278 | Repeat | Note=LRR 3 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000602389 | - | 1 | 8 | 110_133 | -64 | 225 | Repeat | Note=LRR 4 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000602389 | - | 1 | 8 | 135_156 | -64 | 225 | Repeat | Note=LRR 5 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000602389 | - | 1 | 8 | 158_179 | -64 | 225 | Repeat | Note=LRR 6 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000602389 | - | 1 | 8 | 181_202 | -64 | 225 | Repeat | Note=LRR 7 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000602389 | - | 1 | 8 | 41_63 | -64 | 225 | Repeat | Note=LRR 1 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000602389 | - | 1 | 8 | 64_85 | -64 | 225 | Repeat | Note=LRR 2 |
| Hgene | >RSU1 | chr10:16858972 | chr15:89816608 | ENST00000602389 | - | 1 | 8 | 87_109 | -64 | 225 | Repeat | Note=LRR 3 |
Top |
FusionGeneSequence for RSU1_FANCI |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RSU1_ENST00000377921_chr10_16858972_-_FANCI_ENST00000300027_chr15_89816608_+_1011aa MSKSLKKLVEESREKNQPEVDMSDRGISNMLDVNGLCRTARRFQXXLKSLQHCSSSVCNKNTKISGPGAXSFKDFGCKELXGSSTPPRLK ISSESSSSXILCFNHDLGSSEEXRSXLGPCYSGPRRTWFHFDGFIWAKEGSXWKNYXNQPKSFXNAKPACMXARSXYPVGNFXDPXDDQT RNFGAGPQQGCYQSIFSHQSFLRPAFKYRHVCTLSSSKLFFXSHRSFXLFVLSAPSDCTKAAXGSAAPSQSQHVNERLLDTCPSESYVCQ PAXCPKICSCWVFAAPEELXSFRQPVILSVQSVSQCQSGSCGCSQPLQFCRQXNFLPXDHGXFEEMLKPASXCSTHALXGVLXCSSKELS AGXFSHANSALTVKTVLXAKTXSAASSEIRSLYSDPRRXDLSTRTTGLSAVLYSALFGLVXEYSHTLTAGRGGRGGGRGILRRPRXYIGV HYXXNDXEXAGRLXTGXISRFFSEHQYWHKKXYLCFSCDGSLXGFNRIQFLHKXFQXEXVXGHSELIYVLQKTLXHSXXKSGXSQNXNGQ QDKXXSFVHEICVQSSHCSFQSLAMEIHFNSYFSGRVGKERERKEHLTAVLGGFTENIQCCATVLSAQDSAVSQSSGCHRXGRRRERRCR CQCHSENSIPDPAISEVLVEFTXQSRGRFXXQRSPPASHGSYQFVQVTGALLSSVCADVILDIKDLQGKQPGGCLVLQELDELALQPACF VXESCHSAAXLVPGYPRASGRYRPGCRGGENKPLCNSEFENGCPHCLFTCSESGREGSRRSGLANHQAXGTSEPRNLIRRGLFSGNPTKS ACXESYHHATGNSAYIFPRAGADSSAIRQLCGHLVKGLVQNVHHTYSPCQILSPGVSELRRNSKKYGKAGEAVWFSSDPPVLFFHFLRTE XEXEPELYGREKGETCCRCHSHGQSSSGNQANPXPHLCHRTVXKISHPPFXEVQGEPDAAHEAQHLTRLQDQRKHPRHGSSRGWXRXKXR >In-frame_RSU1_ENST00000377921_chr10_16858972_-_FANCI_ENST00000310775_chr15_89816608_+_1071aa MSKSLKKLVEESREKNQPEVDMSDRGISNMLDVNGLCRTARRFQXXLKSLQHCSSSVCNKNTKISGPGAXSFKDFGCKELXGSSTPPRLK ISSESSSSXILCFNHDLGSSEEXRSXLGPCYSGPRRTWFHFDGFIWAKEGSXWKNYXNQPKSFXNAKPACMXARSXYPVGNFXDPXDDQT RNFGAGPQQGCYQSIFSHQSFLRPAFKYRHVCTLSSSKLFFXSHRSFXLFVLSAPSDCTKAAXGSAAPSQSQHVNERLLDTCPSESYVCQ PAXCPKICSCWVFAAPEELXSFRQPVILSVQSVSQCQSGSCGCSQPLQFCRQXNFLPXDHGXFEEMLKPASXCSTHALXGVLXCSSKELS AGXFSHANSALTVKTVLXAKTXSAASSEIRSLYSDPRRXDLSTRTTGLSAVLYSALFGLVXEYSHTLTAGRGGRGGGRGILRRPRXYIGV HYXXNDXEXAGRLXTGXISRFFSEHQYWHKKXYLCFSCDGSLXGFNRIQFLHKXFQXEXVXGHSELIYVLQKTLXHSXXKSGXSQNXNGQ QDKXXSFVHEICVQSSHCSFQGXYPKPPRKPFCSQVQQXVYALCSECSSAEGTAAKGNRACEWPXWPKPRKDLSEPLXHNSSLAMEIHFN SYFSGRVGKERERKEHLTAVLGGFTENIQCCATVLSAQDSAVSQSSGCHRXGRRRERRCRCQCHSENSIPDPAISEVLVEFTXQSRGRFX XQRSPPASHGSYQFVQVTGALLSSVCADVILDIKDLQGKQPGGCLVLQELDELALQPACFVXESCHSAAXLVPGYPRASGRYRPGCRGGE NKPLCNSEFENGCPHCLFTCSESGREGSRRSGLANHQAXGTSEPRNLIRRGLFSGNPTKSACXESYHHATGNSAYIFPRAGADSSAIRQL CGHLVKGLVQNVHHTYSPCQILSPGVSELRRNSKKYGKAGEAVWFSSDPPVLFFHFLRTEXEXEPELYGREKGETCCRCHSHGQSSSGNQ |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RSU1_ENST00000377921_chr10_16858972_-_FANCI_ENST00000300027_chr15_89816608_+_3034nt ATGTCCAAGTCTCTGAAGAAGTTGGTGGAGGAGAGCCGGGAGAAGAACCAGCCCGAGGTGGACATGAGTGACCGGGGCATCTCCAACATG CTGGATGTCAACGGCCTCTGTAGGACAGCAAGGAGATTCCAATAATAACTTAAGTCCCTTCAGCATTGCTCTTCTTCTGTCTGTAACAAG AATACAAAGATTTCAGGACCAGGTGCTTGATCTTTTAAAGACTTCGGTTGTAAAGAGCTTTAAGGATCTTCAACTCCTCCAAGGCTCAAA ATTTCTTCAGAATCTAGTTCCTCATAGATCTTATGTTTCAACCATGATCTTGGAAGTAGTGAAGAATAGCGTTCATAGCTGGGACCATGT TACTCAGGGCCTCGTAGAACTTGGTTTCATTTTGATGGATTCATATGGGCCAAAGAAGGTTCTTGATGGAAAAACTATTGAAACCAGCCC AAGTCTTTCTAGAATGCCAAACCAGCATGCATGTAAGCTCGGAGCTAATATCCTGTTGGAAACTTTTAAGATCCATGAGATGATCAGACA AGAAATTTTGGAGCAGGTCCTCAACAGGGTTGTTACCAGAGCATCTTCTCCCATCAGTCATTTCTTAGACCTGCTTTCAAATATCGTCAT GTATGCACCCTTAGTTCTTCAAAGTTGTTCTTCTAAAGTCACAGAAGCTTTTGACTATTTGTCCTTTCTGCCCCTTCAGACTGTACAAAG GCTGCTTAAGGCAGTGCAGCCCCTTCTCAAAGTCAGCATGTCAATGAGAGACTGCTTGATACTTGTCCTTCGGAAAGCTATGTTTGCCAA CCAGCTTGATGCCCGAAAATCTGCAGTTGCTGGGTTTTTGCTGCTCCTGAAGAACTTTAAAGTTTTAGGCAGCCTGTCATCCTCTCAGTG CAGTCAGTCTCTCAGTGTCAGTCAGGTTCATGTGGATGTTCACAGCCATTACAATTCTGTCGCCAATGAAACTTTTTGCCTTGAGATCAT GGATAGTTTGAGGAGATGCTTAAGCCAGCAAGCTGATGTTCGACTCATGCTTTATGAGGGGTTTTATGATGTTCTTCGAAGGAACTCTCA GCTGGCTAATTCAGTCATGCAAACTCTGCTCTCACAGTTAAAACAGTTCTATGAGCCAAAACCTGATCTGCTGCCTCCTCTGAAATTAGA AGCTTGTATTCTGACCCAAGGAGATAAGATCTCTCTACAAGAACCACTGGATTATCTGCTGTGTTGTATTCAGCATTGTTTGGCCTGGTA TAAGAATACAGTCATACCCTTACAGCAGGGAGAGGAGGAAGAGGAGGAGGAAGAGGCATTCTACGAAGACCTAGATGATATATTGGAGTC CATTACTAATAGAATGATTAAGAGTGAGCTGGAAGACTTTGAACTGGATAAATCAGCAGATTTTTCTCAGAGCACCAGTATTGGCATAAA AAATAATATCTGTGCTTTTCTTGTGATGGGAGTTTGTGAGGTTTTAATAGAATACAATTTCTCCATAAGTAGTTTCAGTAAGAATAGGTT TGAGGACATTCTGAGCTTATTTATGTGTTACAAAAAACTCTCTGACATTCTTAATGAAAAAGCGGGTAAAGCCAAAACTAAAATGGCCAA CAAGACAAGTGATAGTCTTTTGTCCATGAAATTTGTGTCCAGTCTTCTCACTGCTCTTTTCAGAGTCTTGCTATGGAGATACACTTCAAT TCCTACTTCAGTGGAAGAGTCGGGAAAGAAAGAGAAAGGAAAGAGCATCTCACTGCTGTGCTTGGAGGGTTTACAGAAAATATTCAGTGC TGTGCAACAGTTCTATCAGCCCAAGATTCAGCAGTTTCTCAGAGCTCTGGATGTCACAGATAAGGAAGGAGAAGAGAGAGAAGATGCAGA TGTCAGTGTCACTCAGAGAACAGCATTCCAGATCCGGCAATTTCAGAGGTCCTTGTTGAATTTACTTAGCAGTCAAGAGGAAGATTTTAA TAGCAAAGAAGCCCTCCTGCTAGTCACGGTTCTTACCAGTTTGTCCAAGTTACTGGAGCCCTCCTCTCCTCAGTTTGTGCAGATGTTATC CTGGACATCAAAGATTTGCAAGGAAAACAGCCGGGAGGATGCCTTGTTTTGCAAGAGCTTGATGAACTTGCTCTTCAGCCTGCATGTTTC GTATAAGAGTCCTGTCATTCTGCTGCGTGACTTGTCCCAGGATATCCACGGGCATCTGGGAGATATAGACCAGGATGTAGAGGTGGAGAA AACAAACCACTTTGCAATAGTGAATTTGAGAACGGCTGCCCCCACTGTCTGTTTACTTGTTCTGAGTCAGGCCGAGAAGGTTCTAGAAGA AGTGGACTGGCTAATCACCAAGCTTAAGGGACAAGTGAGCCAAGAAACCTTATCAGAAGAGGCCTCTTCTCAGGCAACCCTACCAAATCA GCCTGTTGAGAAAGCTATCATCATGCAACTGGGAACTCTGCTTACATTTTTCCACGAGCTGGTGCAGACAGCTCTGCCATCAGGCAGCTG TGTGGACACCTTGTTAAAGGACTTGTGCAAAATGTACACCACACTTACAGCCCTTGTCAGATATTATCTCCAGGTGTGTCAGAGCTCCGG AGGAATTCCAAAAAATATGGAAAAGCTGGTGAAGCTGTCTGGTTCTCATCTGACCCCCCTGTGTTATTCTTTCATTTCTTACGTACAGAA TAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAA GCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCA CATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGA >In-frame_RSU1_ENST00000377921_chr10_16858972_-_FANCI_ENST00000310775_chr15_89816608_+_3214nt ATGTCCAAGTCTCTGAAGAAGTTGGTGGAGGAGAGCCGGGAGAAGAACCAGCCCGAGGTGGACATGAGTGACCGGGGCATCTCCAACATG CTGGATGTCAACGGCCTCTGTAGGACAGCAAGGAGATTCCAATAATAACTTAAGTCCCTTCAGCATTGCTCTTCTTCTGTCTGTAACAAG AATACAAAGATTTCAGGACCAGGTGCTTGATCTTTTAAAGACTTCGGTTGTAAAGAGCTTTAAGGATCTTCAACTCCTCCAAGGCTCAAA ATTTCTTCAGAATCTAGTTCCTCATAGATCTTATGTTTCAACCATGATCTTGGAAGTAGTGAAGAATAGCGTTCATAGCTGGGACCATGT TACTCAGGGCCTCGTAGAACTTGGTTTCATTTTGATGGATTCATATGGGCCAAAGAAGGTTCTTGATGGAAAAACTATTGAAACCAGCCC AAGTCTTTCTAGAATGCCAAACCAGCATGCATGTAAGCTCGGAGCTAATATCCTGTTGGAAACTTTTAAGATCCATGAGATGATCAGACA AGAAATTTTGGAGCAGGTCCTCAACAGGGTTGTTACCAGAGCATCTTCTCCCATCAGTCATTTCTTAGACCTGCTTTCAAATATCGTCAT GTATGCACCCTTAGTTCTTCAAAGTTGTTCTTCTAAAGTCACAGAAGCTTTTGACTATTTGTCCTTTCTGCCCCTTCAGACTGTACAAAG GCTGCTTAAGGCAGTGCAGCCCCTTCTCAAAGTCAGCATGTCAATGAGAGACTGCTTGATACTTGTCCTTCGGAAAGCTATGTTTGCCAA CCAGCTTGATGCCCGAAAATCTGCAGTTGCTGGGTTTTTGCTGCTCCTGAAGAACTTTAAAGTTTTAGGCAGCCTGTCATCCTCTCAGTG CAGTCAGTCTCTCAGTGTCAGTCAGGTTCATGTGGATGTTCACAGCCATTACAATTCTGTCGCCAATGAAACTTTTTGCCTTGAGATCAT GGATAGTTTGAGGAGATGCTTAAGCCAGCAAGCTGATGTTCGACTCATGCTTTATGAGGGGTTTTATGATGTTCTTCGAAGGAACTCTCA GCTGGCTAATTCAGTCATGCAAACTCTGCTCTCACAGTTAAAACAGTTCTATGAGCCAAAACCTGATCTGCTGCCTCCTCTGAAATTAGA AGCTTGTATTCTGACCCAAGGAGATAAGATCTCTCTACAAGAACCACTGGATTATCTGCTGTGTTGTATTCAGCATTGTTTGGCCTGGTA TAAGAATACAGTCATACCCTTACAGCAGGGAGAGGAGGAAGAGGAGGAGGAAGAGGCATTCTACGAAGACCTAGATGATATATTGGAGTC CATTACTAATAGAATGATTAAGAGTGAGCTGGAAGACTTTGAACTGGATAAATCAGCAGATTTTTCTCAGAGCACCAGTATTGGCATAAA AAATAATATCTGTGCTTTTCTTGTGATGGGAGTTTGTGAGGTTTTAATAGAATACAATTTCTCCATAAGTAGTTTCAGTAAGAATAGGTT TGAGGACATTCTGAGCTTATTTATGTGTTACAAAAAACTCTCTGACATTCTTAATGAAAAAGCGGGTAAAGCCAAAACTAAAATGGCCAA CAAGACAAGTGATAGTCTTTTGTCCATGAAATTTGTGTCCAGTCTTCTCACTGCTCTTTTCAGGGATAGTATCCAAAGCCACCAAGAAAG CCTTTCTGTTCTCAGGTCCAGCAATGAGTTTATGCGCTATGCAGTGAATGTAGCTCTGCAGAAGGTACAGCAGCTAAAGGAAACAGGGCA TGTGAGTGGCCCTGATGGCCAAAACCCAGAAAAGATCTTTCAGAACCTCTGTGACATAACTCGAGTCTTGCTATGGAGATACACTTCAAT TCCTACTTCAGTGGAAGAGTCGGGAAAGAAAGAGAAAGGAAAGAGCATCTCACTGCTGTGCTTGGAGGGTTTACAGAAAATATTCAGTGC TGTGCAACAGTTCTATCAGCCCAAGATTCAGCAGTTTCTCAGAGCTCTGGATGTCACAGATAAGGAAGGAGAAGAGAGAGAAGATGCAGA TGTCAGTGTCACTCAGAGAACAGCATTCCAGATCCGGCAATTTCAGAGGTCCTTGTTGAATTTACTTAGCAGTCAAGAGGAAGATTTTAA TAGCAAAGAAGCCCTCCTGCTAGTCACGGTTCTTACCAGTTTGTCCAAGTTACTGGAGCCCTCCTCTCCTCAGTTTGTGCAGATGTTATC CTGGACATCAAAGATTTGCAAGGAAAACAGCCGGGAGGATGCCTTGTTTTGCAAGAGCTTGATGAACTTGCTCTTCAGCCTGCATGTTTC GTATAAGAGTCCTGTCATTCTGCTGCGTGACTTGTCCCAGGATATCCACGGGCATCTGGGAGATATAGACCAGGATGTAGAGGTGGAGAA AACAAACCACTTTGCAATAGTGAATTTGAGAACGGCTGCCCCCACTGTCTGTTTACTTGTTCTGAGTCAGGCCGAGAAGGTTCTAGAAGA AGTGGACTGGCTAATCACCAAGCTTAAGGGACAAGTGAGCCAAGAAACCTTATCAGAAGAGGCCTCTTCTCAGGCAACCCTACCAAATCA GCCTGTTGAGAAAGCTATCATCATGCAACTGGGAACTCTGCTTACATTTTTCCACGAGCTGGTGCAGACAGCTCTGCCATCAGGCAGCTG TGTGGACACCTTGTTAAAGGACTTGTGCAAAATGTACACCACACTTACAGCCCTTGTCAGATATTATCTCCAGGTGTGTCAGAGCTCCGG AGGAATTCCAAAAAATATGGAAAAGCTGGTGAAGCTGTCTGGTTCTCATCTGACCCCCCTGTGTTATTCTTTCATTTCTTACGTACAGAA TAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAA GCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCA CATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RSU1_ENST00000377921_chr10_16858972_-_FANCI_ENST00000300027_chr15_89816608_+_4138nt GGGCAGCTGGAGTGCGTTCTGCCGAAGCTTGTGGTTGCACGCCCATCGTCTTAGGGGCTACCTTCCGTGGTGAGTGTGTGCGGTGTTGCA CTTGGGGTTGCTTCTCGCTGCGTGGCCGCAGCGGGGCTGAACCCTTCCCACTCCATCCCCTCCCCGCACCCGGACCAGCCCCTGGGACGC CCTCGGACGCCCACCCGCTCCAACCCTGGGGAAGCCTCAGAGTGGCAGCGAAGGCCTCTTGCCTTTCCGCCTCTGCGCTTGCTGTCATCG CCCACGTGCTTTGTTGTTGTTCGGTGCAGACCATGTCCAAGTCTCTGAAGAAGTTGGTGGAGGAGAGCCGGGAGAAGAACCAGCCCGAGG TGGACATGAGTGACCGGGGCATCTCCAACATGCTGGATGTCAACGGCCTCTGTAGGACAGCAAGGAGATTCCAATAATAACTTAAGTCCC TTCAGCATTGCTCTTCTTCTGTCTGTAACAAGAATACAAAGATTTCAGGACCAGGTGCTTGATCTTTTAAAGACTTCGGTTGTAAAGAGC TTTAAGGATCTTCAACTCCTCCAAGGCTCAAAATTTCTTCAGAATCTAGTTCCTCATAGATCTTATGTTTCAACCATGATCTTGGAAGTA GTGAAGAATAGCGTTCATAGCTGGGACCATGTTACTCAGGGCCTCGTAGAACTTGGTTTCATTTTGATGGATTCATATGGGCCAAAGAAG GTTCTTGATGGAAAAACTATTGAAACCAGCCCAAGTCTTTCTAGAATGCCAAACCAGCATGCATGTAAGCTCGGAGCTAATATCCTGTTG GAAACTTTTAAGATCCATGAGATGATCAGACAAGAAATTTTGGAGCAGGTCCTCAACAGGGTTGTTACCAGAGCATCTTCTCCCATCAGT CATTTCTTAGACCTGCTTTCAAATATCGTCATGTATGCACCCTTAGTTCTTCAAAGTTGTTCTTCTAAAGTCACAGAAGCTTTTGACTAT TTGTCCTTTCTGCCCCTTCAGACTGTACAAAGGCTGCTTAAGGCAGTGCAGCCCCTTCTCAAAGTCAGCATGTCAATGAGAGACTGCTTG ATACTTGTCCTTCGGAAAGCTATGTTTGCCAACCAGCTTGATGCCCGAAAATCTGCAGTTGCTGGGTTTTTGCTGCTCCTGAAGAACTTT AAAGTTTTAGGCAGCCTGTCATCCTCTCAGTGCAGTCAGTCTCTCAGTGTCAGTCAGGTTCATGTGGATGTTCACAGCCATTACAATTCT GTCGCCAATGAAACTTTTTGCCTTGAGATCATGGATAGTTTGAGGAGATGCTTAAGCCAGCAAGCTGATGTTCGACTCATGCTTTATGAG GGGTTTTATGATGTTCTTCGAAGGAACTCTCAGCTGGCTAATTCAGTCATGCAAACTCTGCTCTCACAGTTAAAACAGTTCTATGAGCCA AAACCTGATCTGCTGCCTCCTCTGAAATTAGAAGCTTGTATTCTGACCCAAGGAGATAAGATCTCTCTACAAGAACCACTGGATTATCTG CTGTGTTGTATTCAGCATTGTTTGGCCTGGTATAAGAATACAGTCATACCCTTACAGCAGGGAGAGGAGGAAGAGGAGGAGGAAGAGGCA TTCTACGAAGACCTAGATGATATATTGGAGTCCATTACTAATAGAATGATTAAGAGTGAGCTGGAAGACTTTGAACTGGATAAATCAGCA GATTTTTCTCAGAGCACCAGTATTGGCATAAAAAATAATATCTGTGCTTTTCTTGTGATGGGAGTTTGTGAGGTTTTAATAGAATACAAT TTCTCCATAAGTAGTTTCAGTAAGAATAGGTTTGAGGACATTCTGAGCTTATTTATGTGTTACAAAAAACTCTCTGACATTCTTAATGAA AAAGCGGGTAAAGCCAAAACTAAAATGGCCAACAAGACAAGTGATAGTCTTTTGTCCATGAAATTTGTGTCCAGTCTTCTCACTGCTCTT TTCAGAGTCTTGCTATGGAGATACACTTCAATTCCTACTTCAGTGGAAGAGTCGGGAAAGAAAGAGAAAGGAAAGAGCATCTCACTGCTG TGCTTGGAGGGTTTACAGAAAATATTCAGTGCTGTGCAACAGTTCTATCAGCCCAAGATTCAGCAGTTTCTCAGAGCTCTGGATGTCACA GATAAGGAAGGAGAAGAGAGAGAAGATGCAGATGTCAGTGTCACTCAGAGAACAGCATTCCAGATCCGGCAATTTCAGAGGTCCTTGTTG AATTTACTTAGCAGTCAAGAGGAAGATTTTAATAGCAAAGAAGCCCTCCTGCTAGTCACGGTTCTTACCAGTTTGTCCAAGTTACTGGAG CCCTCCTCTCCTCAGTTTGTGCAGATGTTATCCTGGACATCAAAGATTTGCAAGGAAAACAGCCGGGAGGATGCCTTGTTTTGCAAGAGC TTGATGAACTTGCTCTTCAGCCTGCATGTTTCGTATAAGAGTCCTGTCATTCTGCTGCGTGACTTGTCCCAGGATATCCACGGGCATCTG GGAGATATAGACCAGGATGTAGAGGTGGAGAAAACAAACCACTTTGCAATAGTGAATTTGAGAACGGCTGCCCCCACTGTCTGTTTACTT GTTCTGAGTCAGGCCGAGAAGGTTCTAGAAGAAGTGGACTGGCTAATCACCAAGCTTAAGGGACAAGTGAGCCAAGAAACCTTATCAGAA GAGGCCTCTTCTCAGGCAACCCTACCAAATCAGCCTGTTGAGAAAGCTATCATCATGCAACTGGGAACTCTGCTTACATTTTTCCACGAG CTGGTGCAGACAGCTCTGCCATCAGGCAGCTGTGTGGACACCTTGTTAAAGGACTTGTGCAAAATGTACACCACACTTACAGCCCTTGTC AGATATTATCTCCAGGTGTGTCAGAGCTCCGGAGGAATTCCAAAAAATATGGAAAAGCTGGTGAAGCTGTCTGGTTCTCATCTGACCCCC CTGTGTTATTCTTTCATTTCTTACGTACAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCC ACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTT TCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTT CTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAGCCAAGAAGAAAAGGAAA AAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGCCCCTTGTCCTGTAGTCC ACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGGCAGGTCCTGCTACTGAA AAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACCCCGATGAAGCTCCACGG GAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGTTCAATTATCTGGTAAAT ATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAGAAGTGAGCAAAGGAGCT TAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGGGTCTGTTTTCTTTTTAT ATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAGTTTGTTTTTCTGTCACC TATAGAGTGCAAGAATGCACTCTATAGAATAAATTATCTTTAAACATTTCTTCTGTGGTTGAAGTAGGGGACAGGTACAGGTAGAATATT >In-frame_RSU1_ENST00000377921_chr10_16858972_-_FANCI_ENST00000310775_chr15_89816608_+_4186nt GGGCAGCTGGAGTGCGTTCTGCCGAAGCTTGTGGTTGCACGCCCATCGTCTTAGGGGCTACCTTCCGTGGTGAGTGTGTGCGGTGTTGCA CTTGGGGTTGCTTCTCGCTGCGTGGCCGCAGCGGGGCTGAACCCTTCCCACTCCATCCCCTCCCCGCACCCGGACCAGCCCCTGGGACGC CCTCGGACGCCCACCCGCTCCAACCCTGGGGAAGCCTCAGAGTGGCAGCGAAGGCCTCTTGCCTTTCCGCCTCTGCGCTTGCTGTCATCG CCCACGTGCTTTGTTGTTGTTCGGTGCAGACCATGTCCAAGTCTCTGAAGAAGTTGGTGGAGGAGAGCCGGGAGAAGAACCAGCCCGAGG TGGACATGAGTGACCGGGGCATCTCCAACATGCTGGATGTCAACGGCCTCTGTAGGACAGCAAGGAGATTCCAATAATAACTTAAGTCCC TTCAGCATTGCTCTTCTTCTGTCTGTAACAAGAATACAAAGATTTCAGGACCAGGTGCTTGATCTTTTAAAGACTTCGGTTGTAAAGAGC TTTAAGGATCTTCAACTCCTCCAAGGCTCAAAATTTCTTCAGAATCTAGTTCCTCATAGATCTTATGTTTCAACCATGATCTTGGAAGTA GTGAAGAATAGCGTTCATAGCTGGGACCATGTTACTCAGGGCCTCGTAGAACTTGGTTTCATTTTGATGGATTCATATGGGCCAAAGAAG GTTCTTGATGGAAAAACTATTGAAACCAGCCCAAGTCTTTCTAGAATGCCAAACCAGCATGCATGTAAGCTCGGAGCTAATATCCTGTTG GAAACTTTTAAGATCCATGAGATGATCAGACAAGAAATTTTGGAGCAGGTCCTCAACAGGGTTGTTACCAGAGCATCTTCTCCCATCAGT CATTTCTTAGACCTGCTTTCAAATATCGTCATGTATGCACCCTTAGTTCTTCAAAGTTGTTCTTCTAAAGTCACAGAAGCTTTTGACTAT TTGTCCTTTCTGCCCCTTCAGACTGTACAAAGGCTGCTTAAGGCAGTGCAGCCCCTTCTCAAAGTCAGCATGTCAATGAGAGACTGCTTG ATACTTGTCCTTCGGAAAGCTATGTTTGCCAACCAGCTTGATGCCCGAAAATCTGCAGTTGCTGGGTTTTTGCTGCTCCTGAAGAACTTT AAAGTTTTAGGCAGCCTGTCATCCTCTCAGTGCAGTCAGTCTCTCAGTGTCAGTCAGGTTCATGTGGATGTTCACAGCCATTACAATTCT GTCGCCAATGAAACTTTTTGCCTTGAGATCATGGATAGTTTGAGGAGATGCTTAAGCCAGCAAGCTGATGTTCGACTCATGCTTTATGAG GGGTTTTATGATGTTCTTCGAAGGAACTCTCAGCTGGCTAATTCAGTCATGCAAACTCTGCTCTCACAGTTAAAACAGTTCTATGAGCCA AAACCTGATCTGCTGCCTCCTCTGAAATTAGAAGCTTGTATTCTGACCCAAGGAGATAAGATCTCTCTACAAGAACCACTGGATTATCTG CTGTGTTGTATTCAGCATTGTTTGGCCTGGTATAAGAATACAGTCATACCCTTACAGCAGGGAGAGGAGGAAGAGGAGGAGGAAGAGGCA TTCTACGAAGACCTAGATGATATATTGGAGTCCATTACTAATAGAATGATTAAGAGTGAGCTGGAAGACTTTGAACTGGATAAATCAGCA GATTTTTCTCAGAGCACCAGTATTGGCATAAAAAATAATATCTGTGCTTTTCTTGTGATGGGAGTTTGTGAGGTTTTAATAGAATACAAT TTCTCCATAAGTAGTTTCAGTAAGAATAGGTTTGAGGACATTCTGAGCTTATTTATGTGTTACAAAAAACTCTCTGACATTCTTAATGAA AAAGCGGGTAAAGCCAAAACTAAAATGGCCAACAAGACAAGTGATAGTCTTTTGTCCATGAAATTTGTGTCCAGTCTTCTCACTGCTCTT TTCAGGGATAGTATCCAAAGCCACCAAGAAAGCCTTTCTGTTCTCAGGTCCAGCAATGAGTTTATGCGCTATGCAGTGAATGTAGCTCTG CAGAAGGTACAGCAGCTAAAGGAAACAGGGCATGTGAGTGGCCCTGATGGCCAAAACCCAGAAAAGATCTTTCAGAACCTCTGTGACATA ACTCGAGTCTTGCTATGGAGATACACTTCAATTCCTACTTCAGTGGAAGAGTCGGGAAAGAAAGAGAAAGGAAAGAGCATCTCACTGCTG TGCTTGGAGGGTTTACAGAAAATATTCAGTGCTGTGCAACAGTTCTATCAGCCCAAGATTCAGCAGTTTCTCAGAGCTCTGGATGTCACA GATAAGGAAGGAGAAGAGAGAGAAGATGCAGATGTCAGTGTCACTCAGAGAACAGCATTCCAGATCCGGCAATTTCAGAGGTCCTTGTTG AATTTACTTAGCAGTCAAGAGGAAGATTTTAATAGCAAAGAAGCCCTCCTGCTAGTCACGGTTCTTACCAGTTTGTCCAAGTTACTGGAG CCCTCCTCTCCTCAGTTTGTGCAGATGTTATCCTGGACATCAAAGATTTGCAAGGAAAACAGCCGGGAGGATGCCTTGTTTTGCAAGAGC TTGATGAACTTGCTCTTCAGCCTGCATGTTTCGTATAAGAGTCCTGTCATTCTGCTGCGTGACTTGTCCCAGGATATCCACGGGCATCTG GGAGATATAGACCAGGATGTAGAGGTGGAGAAAACAAACCACTTTGCAATAGTGAATTTGAGAACGGCTGCCCCCACTGTCTGTTTACTT GTTCTGAGTCAGGCCGAGAAGGTTCTAGAAGAAGTGGACTGGCTAATCACCAAGCTTAAGGGACAAGTGAGCCAAGAAACCTTATCAGAA GAGGCCTCTTCTCAGGCAACCCTACCAAATCAGCCTGTTGAGAAAGCTATCATCATGCAACTGGGAACTCTGCTTACATTTTTCCACGAG CTGGTGCAGACAGCTCTGCCATCAGGCAGCTGTGTGGACACCTTGTTAAAGGACTTGTGCAAAATGTACACCACACTTACAGCCCTTGTC AGATATTATCTCCAGGTGTGTCAGAGCTCCGGAGGAATTCCAAAAAATATGGAAAAGCTGGTGAAGCTGTCTGGTTCTCATCTGACCCCC CTGTGTTATTCTTTCATTTCTTACGTACAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCC ACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTT TCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTT CTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAGCCAAGAAGAAAAGGAAA AAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGCCCCTTGTCCTGTAGTCC ACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGGCAGGTCCTGCTACTGAA AAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACCCCGATGAAGCTCCACGG GAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGTTCAATTATCTGGTAAAT ATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAGAAGTGAGCAAAGGAGCT TAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGGGTCTGTTTTCTTTTTAT ATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAGTTTGTTTTTCTGTCACC |
Top |
FusionGenePPI for RSU1_FANCI |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RSU1 | ACP6, ILK, HGS, GSK3B, ELAVL1, LRRK1, APP, VCP, FN1, LRCH3, FAM114A1, PARVA, PPAT, SEC24D, SUGT1, LIMS1, PARVB, PARVG, CBS, HNRNPA3, NDUFA8, NTMT1, PFKP, DAZAP1, DHX15, FLNB, HADH, USP3, TIAL1, TKT | FANCI | PTP4A3, ILK, C20orf24, PELO, GSTK1, NEK6, MAGED1, BRF2, MYC, USP36, ATM, CAMKK2, CLN3, PRKAB2, RAD18, FAN1, POLN, FANCD2, WDR48, PIDD1, SIRT7, FANCL, CUL3, APP, VCP, MMS19, HBS1L, PTPLAD1, EMD, MOV10, NXF1, ABCE1, IMPDH2, NTRK1, CEP120, DDOST, STXBP2, PAPSS1, CIR1, DGCR8, IMPACT, PRR3, DPY30, PLEKHA8, C1orf86, TIMM23, REV1, SNW1, CDC5L, POU5F1, PPM1A, RUNX3, UBL5, FANCI, MCM2, MCM3, MCM5, HELQ, FANCM, MTNR1B, PHLPP1, AKT1, PHLPP2, ATR, BRCA2, TRIM25, UHRF2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for RSU1_FANCI |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for RSU1_FANCI |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | RSU1 | C0029456 | Osteoporosis | 1 | CTD_human |
| Hgene | RSU1 | C0263454 | Chloracne | 1 | CTD_human |
| Tgene | FANCI | C1836861 | FANCONI ANEMIA, COMPLEMENTATION GROUP I | 2 | CTD_human;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|