|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 32255 |
FusionGeneSummary for RRNAD1_CTSS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RRNAD1_CTSS | Fusion gene ID: 32255 | Hgene | Tgene | Gene symbol | RRNAD1 | CTSS | Gene ID | 51093 | 1520 |
| Gene name | ribosomal RNA adenine dimethylase domain containing 1 | cathepsin S | |
| Synonyms | C1orf66|CGI-41|METTL25B | - | |
| Cytomap | 1q23.1 | 1q21.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein RRNAD1ribosomal RNA adenine dimethylase domain-containing protein 1 | cathepsin S | |
| Modification date | 20180519 | 20180527 | |
| UniProtAcc | Q96FB5 | P25774 | |
| Ensembl transtripts involved in fusion gene | ENST00000368218, ENST00000368216, ENST00000524343, ENST00000476229, ENST00000481920, | ENST00000368985, ENST00000448301, ENST00000480760, | |
| Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 12 X 10 X 8=960 |
| # samples | 2 | 12 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(12/960*10)=-3 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RRNAD1 [Title/Abstract] AND CTSS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | CTSS | GO:0006508 | proteolysis | 12788072|22864553 |
| Tgene | CTSS | GO:0010447 | response to acidic pH | 22864553 |
| Tgene | CTSS | GO:0016485 | protein processing | 22864553 |
| Tgene | CTSS | GO:0030574 | collagen catabolic process | 22952693 |
| Tgene | CTSS | GO:0034769 | basement membrane disassembly | 22952693 |
| Tgene | CTSS | GO:0048002 | antigen processing and presentation of peptide antigen | 8612130 |
| Tgene | CTSS | GO:0051603 | proteolysis involved in cellular protein catabolic process | 22952693 |
| Tgene | CTSS | GO:2001259 | positive regulation of cation channel activity | 22864553 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | UCEC | TCGA-AJ-A3BF-01A | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000368218 | ENST00000368985 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| In-frame | ENST00000368218 | ENST00000448301 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| 5CDS-5UTR | ENST00000368218 | ENST00000480760 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| In-frame | ENST00000368216 | ENST00000368985 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| In-frame | ENST00000368216 | ENST00000448301 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| 5CDS-5UTR | ENST00000368216 | ENST00000480760 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| In-frame | ENST00000524343 | ENST00000368985 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| In-frame | ENST00000524343 | ENST00000448301 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| 5CDS-5UTR | ENST00000524343 | ENST00000480760 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| intron-3CDS | ENST00000476229 | ENST00000368985 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| intron-3CDS | ENST00000476229 | ENST00000448301 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| intron-5UTR | ENST00000476229 | ENST00000480760 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| intron-3CDS | ENST00000481920 | ENST00000368985 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| intron-3CDS | ENST00000481920 | ENST00000448301 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
| intron-5UTR | ENST00000481920 | ENST00000480760 | RRNAD1 | chr1 | 156699007 | + | CTSS | chr1 | 150730456 | - |
Top |
FusionProtFeatures for RRNAD1_CTSS |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RRNAD1 | CTSS |
| Thiol protease. Key protease responsible for the removalof the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to thespecificities of cathepsin L. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RRNAD1 | chr1:156699007 | chr1:150730456 | ENST00000368216 | + | 1 | 8 | 186_210 | 37 | 476 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >RRNAD1 | chr1:156699007 | chr1:150730456 | ENST00000368216 | + | 1 | 8 | 406_426 | 37 | 476 | Transmembrane | Helical |
Top |
FusionGeneSequence for RRNAD1_CTSS |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RRNAD1_ENST00000368218_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_327aa MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIINEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL RVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFM TTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN >In-frame_RRNAD1_ENST00000368218_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_277aa MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIINEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMGSCGACWAFSAV GALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF >In-frame_RRNAD1_ENST00000368216_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_327aa MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIINEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL RVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFM TTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN >In-frame_RRNAD1_ENST00000368216_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_277aa MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIINEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMGSCGACWAFSAV GALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF >In-frame_RRNAD1_ENST00000524343_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_327aa MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIINEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSL RVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFM TTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQN >In-frame_RRNAD1_ENST00000524343_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_277aa MPGISARGLSHEGRKQLAVNLTRVLALYRSILDAYIINEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMGSCGACWAFSAV GALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGRE DVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RRNAD1_ENST00000368218_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_981nt ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGATGAGTTCCCTG AGAGTTCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGAAAGGG TGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAA ACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATG ACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCCTACAAAGCCATGGATCAGAAATGTCAATAT GACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAA GGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGTACTCAGAAT GTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTTGTGAAAAACAGCTGGGGCCACAACTTTGGT >In-frame_RRNAD1_ENST00000368218_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_831nt ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTG GGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATAT GGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCC TACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAA GATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGT GTCTACTATGAACCATCCTGTACTCAGAATGTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTT GTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGAAGGATATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTT >In-frame_RRNAD1_ENST00000368216_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_981nt ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGATGAGTTCCCTG AGAGTTCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGAAAGGG TGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAA ACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATG ACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCCTACAAAGCCATGGATCAGAAATGTCAATAT GACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAA GGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGTACTCAGAAT GTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTTGTGAAAAACAGCTGGGGCCACAACTTTGGT >In-frame_RRNAD1_ENST00000368216_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_831nt ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTG GGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATAT GGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCC TACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAA GATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGT GTCTACTATGAACCATCCTGTACTCAGAATGTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTT GTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGAAGGATATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTT >In-frame_RRNAD1_ENST00000524343_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_981nt ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGATGAGTTCCCTG AGAGTTCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGAAAGGG TGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAA ACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATG ACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCCTACAAAGCCATGGATCAGAAATGTCAATAT GACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAA GGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGTACTCAGAAT GTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTTGTGAAAAACAGCTGGGGCCACAACTTTGGT >In-frame_RRNAD1_ENST00000524343_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_831nt ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTG GGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATAT GGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCC TACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAA GATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGT GTCTACTATGAACCATCCTGTACTCAGAATGTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTT GTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGAAGGATATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RRNAD1_ENST00000368218_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_4494nt AAGCGTCCGGAGCCGGATGCGGAAATCGGTGCGCGCCGACGAAGCCCGGGAAGGCAGGCGCGCGGGTTAGAACGCGCCAGAGGTCGGCGC GCGCACACCCGCACCGCCCCGACCCCAGGTAGTGAGGCCAGTGATTCCGAGTGTGTGAGGAGCGGCAGTGGCGGCGGAGGAGGGGGCGGC GTGGGTGGGGGCGGGGGCGGGATGCGCTCCCCGGCCCCTCTAGCCCCGTGGTGGTACAACGCGAAGGTGTGGGAAGGCCGCGATAAACCG GAACTGCAGCCCGCCGGACACCTCCGGCTTCACTTCCGTAAGAGGAGAGGAGTGTACGGCAAGGGGCGGGAACTGGAACTTGGCCCGCCT CGTTGTGAGCTGAGCTCAGCGGCACGCTTTTGTGGCGTCACTGCACTGTTACCCCGCCCTACGTGTCTCTGACGCTGACACCTTCTCACT GTGAAACGTCGCGACCTGTGACGTCTGGGGGGCGCCTCAAATCTTCCACTCCAGCATCGGATCCCGGAAAGGCAGCGTCGGAGACTGGAC CCAAAACTCTTCCTGTTCTGCCTGCAGAGTTGAGCCCCGTCCGGGTCCTGGACCCGCGTAGTACTGACCCTGGATCCCTGTTCACTGCGT TCTCGCTCCCCGCGCTCCCTGCTGGACCCCGGGATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTT AACCTCACCCGTGTCCTGGCACTCTACCGTTCCATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAG AATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGACC AGTGAAGAAGTGATGTCTTTGATGAGTTCCCTGAGAGTTCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATA TTGCCTGATTCTGTGGACTGGAGAGAGAAAGGGTGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCT GTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAA TATGGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTAT CCCTACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGA GAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGT GGTGTCTACTATGAACCATCCTGTACTCAGAATGTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGG CTTGTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGAAGGATATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGC TTTCCCTCTTACCCAGAAATCTAGAGGATCTCTCCTTTTTATAACAAATCAAGAAATATGAAGCACTTTCTCTTAACTTAATTTTTCCTG CTGTATCCAGAAGAAATAATTGTGTCATGATTAATGTGTATTTACTGTACTAATTAGAAAATATAGTTTGAGGCCGGGCACGGTGGCTCA CGCCTGTAATCCCAGTACTTGGGAGGCCAAGGCAGGCATATCAACTTGAGGCCAGGAGTTAAAGAGCAGCCTGGCTAACATGGTGAAACC CCATCTCTACTAAAAATACAAAAAATTAGCCGAGCACGGTGGTGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCACGAGATTCC TTGAACCCAAGAGGTTGAGGCTATGTTGAGCTGAGATCACACCACTGTACTCCAGCCTGGATGACAGAGTGGAGACTCTGTTTCAAAAAA ACAGAAAAGAAAATATAGTTTGATTCTTCATTTTTTTAAATTTGCAAATCTCAGGATAAAGTTTGCTAAGTAAATTAGTAATGTACTATA GATATAACTGTACAAAAATTGTTCAACCTAAAACAATCTGTAATTGCTTATTGTTTTATTGTATACTCTTTGTCTTTTTAAGACCCCTAA TAGCCTTTTGTAACTTGATGGCTTAAAAATACTTAATAAATCTGCCATTTCAAATTTCTATCATTGCCACATACCATTCTTATTCCTAGG CAACTATTAATAATCTATCCTGAGAATATTAATTGTGGTATTCTGGTGATGGGGTTTAGCAACTTTGATGGAAGAAAATATTAGGCTATA AATGTCCTAAGGACTCAGATTGTATCTTTGTACAGAAGAGGATTCAAAACGCCACGTGTAGTGGCTCATGCCTGTAATCCCAACACTTTG GGAGGCTGAAGTAGGAGGATCGTCTTGAGCCCAGGAGTTCAAGACCAGCCTGGACAACATAGTGAGACCTTGTCTCCACAAAAATAAAAA AGAAACTATCCAGGAGTGGTGGTGTGTGCCTGTGGTCCCTGCTATGCAGATGTCTAAGACAGGAGGATCACAAGAGCCCAGGAGGTTGAG AATGCAGTGAGCTTGTAATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTTAAAAAAAGAGGATTCAACACATATT TTTATATTATGTTAAAGTAAAGAAATGCATAAAAGACAAGCACTTTGGAAGAATTATTTTAATGATCAACAATTTAATGTATTAGTCCAA ATTATTTTTACGTAGTCATCAACAATTTGACCAGGGCCTTTATTTGGCAAATAACTGAGCCAACCAGAATAAAATAACCAATACTCCACT GCTCATATTTTTATCTAATTCAGATGGATCTTCCTTACAACTGCTCTAGATTAGTAGATGCATCTAAGCAGGCAGCAGGAACTTTAAATT TTTTAAGTTCATGTCTATGACATGAACAATGTGTGGGATAATGTCATTAATATATCCTAAATTAACCTAAACGTATTTCACTAACTCTGG CTCCTTCTCCATAAAGCACATTTTAAGGAACAAGAATTGCTAAATATAAAAACATAAATAATACCATAATACATGGCTATCATCAAAAGT GTATAGAATATTATAGTTTAAAAGTATTTAGTTGATTACTTTTCAGTTTTGTTTTGTTTTTTGAGACGGAGTCTCACTCTGTTGCCCAGG CTGGAGTGCAGTGGCACCATCTCAGTTCACTGCAACTTCTGCCTCCCGAGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGA ATTATAGGCGTGCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAAAGACAGGGTTTTGCCACATTAGCCAGGCTGGTCTCAAACTC CTGACCTCAGGTGATCCACCCACCCCAGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCACTGAGCCCAGCCTACTTTTCAGTTTTTA ACATAATTTTTGTTTTATCCACAACTTTTCAAGTATTGAAAGTAGAATAAAAACATGGGTTCTTAGTCTTTAGCTATCTGTTAAAGCCTA TGAATGCCTTCTTAAAATCATGTTTTTAAATGCATAAAATATATAGGATTACAAAGGAATCTAATTATATCGAAATACAGTTATTAAAAT GTTAAAAGATAAGTTTGTTATATATTAATATGCATGCTTCTTTATAAATGCATTAAATAAGAGTTAATAGCTATCCTAAATTTGAAATAG TGATAAGCATAATGAAAATAGATGCAAAAAACTAATGTGATATGAAAATATCTGGGTTTTTCTTTTGATGATGAAGTATTGCTAATATTA CCGTGGTTTATGAACTATGTTCAGAATTGAAGAAAATCCTAACTTTCAGTTAGAGGTTAGTGACGGGGTTCAGGACACCCTACACAAAAT ACAGCACTTTGACATATTGAATATTTTAAGCTGAAGGCATTTGAGGAAATTGCAGAAGCAGGAAGGTGACTCTGACCTTCTGCCTGCTGT TCTCCCCAGAAGCAGCCATAAAACCTGGGAAGGATTTTCTGACCTTCCCCTGAAGTAGATCATAAGACTGTCATGTAAGAGGTGCTCTCC TGGCACCCAGAGAAAAGGAGCATCCTTACCTCCAAAAGCACAGGGACACAAAGAGGAATCTAAACAAACAGGCCTCTCAGTTTCCCCCAG TTTATTACATTTAGCTTGTTCACACTTTGCCCTATGACATTTCTACATCACTGGCTGCTCTTCATCAAACCTACTATAAAAAACATTCAA >In-frame_RRNAD1_ENST00000368218_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_1973nt AAGCGTCCGGAGCCGGATGCGGAAATCGGTGCGCGCCGACGAAGCCCGGGAAGGCAGGCGCGCGGGTTAGAACGCGCCAGAGGTCGGCGC GCGCACACCCGCACCGCCCCGACCCCAGGTAGTGAGGCCAGTGATTCCGAGTGTGTGAGGAGCGGCAGTGGCGGCGGAGGAGGGGGCGGC GTGGGTGGGGGCGGGGGCGGGATGCGCTCCCCGGCCCCTCTAGCCCCGTGGTGGTACAACGCGAAGGTGTGGGAAGGCCGCGATAAACCG GAACTGCAGCCCGCCGGACACCTCCGGCTTCACTTCCGTAAGAGGAGAGGAGTGTACGGCAAGGGGCGGGAACTGGAACTTGGCCCGCCT CGTTGTGAGCTGAGCTCAGCGGCACGCTTTTGTGGCGTCACTGCACTGTTACCCCGCCCTACGTGTCTCTGACGCTGACACCTTCTCACT GTGAAACGTCGCGACCTGTGACGTCTGGGGGGCGCCTCAAATCTTCCACTCCAGCATCGGATCCCGGAAAGGCAGCGTCGGAGACTGGAC CCAAAACTCTTCCTGTTCTGCCTGCAGAGTTGAGCCCCGTCCGGGTCCTGGACCCGCGTAGTACTGACCCTGGATCCCTGTTCACTGCGT TCTCGCTCCCCGCGCTCCCTGCTGGACCCCGGGATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTT AACCTCACCCGTGTCCTGGCACTCTACCGTTCCATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAG AATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGGGT TCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCC CAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGAT AACAAGGGCATCGACTCAGACGCTTCCTATCCCTACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGT TCAAAGTACACTGAACTTCCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCG CGTCATCCTTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGTACTCAGAATGTGAATCATGGTGTACTTGTGGTTGGC TATGGTGATCTTAATGGGAAAGAATACTGGCTTGTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGAAGGATATATTCGGATGGCAAGA AATAAAGGAAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTCTCCTTTTTATAACAAATCAAGAAATATG AAGCACTTTCTCTTAACTTAATTTTTCCTGCTGTATCCAGAAGAAATAATTGTGTCATGATTAATGTGTATTTACTGTACTAATTAGAAA ATATAGTTTGAGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGTACTTGGGAGGCCAAGGCAGGCATATCAACTTGAGGCCAGGAGTT AAAGAGCAGCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCGAGCACGGTGGTGCATGCCTGTAATCCCA GCTACTTGGGAGGCTGAGGCACGAGATTCCTTGAACCCAAGAGGTTGAGGCTATGTTGAGCTGAGATCACACCACTGTACTCCAGCCTGG >In-frame_RRNAD1_ENST00000368216_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_4461nt CGCCGACGAAGCCCGGGAAGGCAGGCGCGCGGGTTAGAACGCGCCAGAGGTCGGCGCGCGCACACCCGCACCGCCCCGACCCCAGGTAGT GAGGCCAGTGATTCCGAGTGTGTGAGGAGCGGCAGTGGCGGCGGAGGAGGGGGCGGCGTGGGTGGGGGCGGGGGCGGGATGCGCTCCCCG GCCCCTCTAGCCCCGTGGTGGTACAACGCGAAGGTGTGGGAAGGCCGCGATAAACCGGAACTGCAGCCCGCCGGACACCTCCGGCTTCAC TTCCGTAAGAGGAGAGGAGTGTACGGCAAGGGGCGGGAACTGGAACTTGGCCCGCCTCGTTGTGAGCTGAGCTCAGCGGCACGCTTTTGT GGCGTCACTGCACTGTTACCCCGCCCTACGTGTCTCTGACGCTGACACCTTCTCACTGTGAAACGTCGCGACCTGTGACGTCTGGGGGGC GCCTCAAATCTTCCACTCCAGCATCGGATCCCGGAAAGGCAGCGTCGGAGACTGGACCCAAAACTCTTCCTGTTCTGCCTGCAGAGTTGA GCCCCGTCCGGGTCCTGGACCCGCGTAGTACTGACCCTGGATCCCTGTTCACTGCGTTCTCGCTCCCCGCGCTCCCTGCTGGACCCCGGG ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGATGAGTTCCCTG AGAGTTCCCAGCCAGTGGCAGAGAAATATCACATATAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGAAAGGG TGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAA ACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATG ACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCCTACAAAGCCATGGATCAGAAATGTCAATAT GACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAA GGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGTACTCAGAAT GTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTTGTGAAAAACAGCTGGGGCCACAACTTTGGT GAAGAAGGATATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTCT CCTTTTTATAACAAATCAAGAAATATGAAGCACTTTCTCTTAACTTAATTTTTCCTGCTGTATCCAGAAGAAATAATTGTGTCATGATTA ATGTGTATTTACTGTACTAATTAGAAAATATAGTTTGAGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGTACTTGGGAGGCCAAGGC AGGCATATCAACTTGAGGCCAGGAGTTAAAGAGCAGCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCGA GCACGGTGGTGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCACGAGATTCCTTGAACCCAAGAGGTTGAGGCTATGTTGAGCTG AGATCACACCACTGTACTCCAGCCTGGATGACAGAGTGGAGACTCTGTTTCAAAAAAACAGAAAAGAAAATATAGTTTGATTCTTCATTT TTTTAAATTTGCAAATCTCAGGATAAAGTTTGCTAAGTAAATTAGTAATGTACTATAGATATAACTGTACAAAAATTGTTCAACCTAAAA CAATCTGTAATTGCTTATTGTTTTATTGTATACTCTTTGTCTTTTTAAGACCCCTAATAGCCTTTTGTAACTTGATGGCTTAAAAATACT TAATAAATCTGCCATTTCAAATTTCTATCATTGCCACATACCATTCTTATTCCTAGGCAACTATTAATAATCTATCCTGAGAATATTAAT TGTGGTATTCTGGTGATGGGGTTTAGCAACTTTGATGGAAGAAAATATTAGGCTATAAATGTCCTAAGGACTCAGATTGTATCTTTGTAC AGAAGAGGATTCAAAACGCCACGTGTAGTGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAAGTAGGAGGATCGTCTTGAGCCCA GGAGTTCAAGACCAGCCTGGACAACATAGTGAGACCTTGTCTCCACAAAAATAAAAAAGAAACTATCCAGGAGTGGTGGTGTGTGCCTGT GGTCCCTGCTATGCAGATGTCTAAGACAGGAGGATCACAAGAGCCCAGGAGGTTGAGAATGCAGTGAGCTTGTAATTGCACCACTGCACT CCAGCCTGGGTGACAGAGCAAGACCCTGTCTTAAAAAAAGAGGATTCAACACATATTTTTATATTATGTTAAAGTAAAGAAATGCATAAA AGACAAGCACTTTGGAAGAATTATTTTAATGATCAACAATTTAATGTATTAGTCCAAATTATTTTTACGTAGTCATCAACAATTTGACCA GGGCCTTTATTTGGCAAATAACTGAGCCAACCAGAATAAAATAACCAATACTCCACTGCTCATATTTTTATCTAATTCAGATGGATCTTC CTTACAACTGCTCTAGATTAGTAGATGCATCTAAGCAGGCAGCAGGAACTTTAAATTTTTTAAGTTCATGTCTATGACATGAACAATGTG TGGGATAATGTCATTAATATATCCTAAATTAACCTAAACGTATTTCACTAACTCTGGCTCCTTCTCCATAAAGCACATTTTAAGGAACAA GAATTGCTAAATATAAAAACATAAATAATACCATAATACATGGCTATCATCAAAAGTGTATAGAATATTATAGTTTAAAAGTATTTAGTT GATTACTTTTCAGTTTTGTTTTGTTTTTTGAGACGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCACCATCTCAGTTCACTGC AACTTCTGCCTCCCGAGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTATAGGCGTGCACCACCACGCCCAGCTAATT TTTGTATTTTTAGTAAAGACAGGGTTTTGCCACATTAGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCCACCCCAGCCTCC CAAAGTGCTAAGATTACAGGCGTGAGCCACTGAGCCCAGCCTACTTTTCAGTTTTTAACATAATTTTTGTTTTATCCACAACTTTTCAAG TATTGAAAGTAGAATAAAAACATGGGTTCTTAGTCTTTAGCTATCTGTTAAAGCCTATGAATGCCTTCTTAAAATCATGTTTTTAAATGC ATAAAATATATAGGATTACAAAGGAATCTAATTATATCGAAATACAGTTATTAAAATGTTAAAAGATAAGTTTGTTATATATTAATATGC ATGCTTCTTTATAAATGCATTAAATAAGAGTTAATAGCTATCCTAAATTTGAAATAGTGATAAGCATAATGAAAATAGATGCAAAAAACT AATGTGATATGAAAATATCTGGGTTTTTCTTTTGATGATGAAGTATTGCTAATATTACCGTGGTTTATGAACTATGTTCAGAATTGAAGA AAATCCTAACTTTCAGTTAGAGGTTAGTGACGGGGTTCAGGACACCCTACACAAAATACAGCACTTTGACATATTGAATATTTTAAGCTG AAGGCATTTGAGGAAATTGCAGAAGCAGGAAGGTGACTCTGACCTTCTGCCTGCTGTTCTCCCCAGAAGCAGCCATAAAACCTGGGAAGG ATTTTCTGACCTTCCCCTGAAGTAGATCATAAGACTGTCATGTAAGAGGTGCTCTCCTGGCACCCAGAGAAAAGGAGCATCCTTACCTCC AAAAGCACAGGGACACAAAGAGGAATCTAAACAAACAGGCCTCTCAGTTTCCCCCAGTTTATTACATTTAGCTTGTTCACACTTTGCCCT ATGACATTTCTACATCACTGGCTGCTCTTCATCAAACCTACTATAAAAAACATTCAAGTTCAACTGTTTCTTTGGGCCTTTATTTCCTTA >In-frame_RRNAD1_ENST00000368216_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_1940nt CGCCGACGAAGCCCGGGAAGGCAGGCGCGCGGGTTAGAACGCGCCAGAGGTCGGCGCGCGCACACCCGCACCGCCCCGACCCCAGGTAGT GAGGCCAGTGATTCCGAGTGTGTGAGGAGCGGCAGTGGCGGCGGAGGAGGGGGCGGCGTGGGTGGGGGCGGGGGCGGGATGCGCTCCCCG GCCCCTCTAGCCCCGTGGTGGTACAACGCGAAGGTGTGGGAAGGCCGCGATAAACCGGAACTGCAGCCCGCCGGACACCTCCGGCTTCAC TTCCGTAAGAGGAGAGGAGTGTACGGCAAGGGGCGGGAACTGGAACTTGGCCCGCCTCGTTGTGAGCTGAGCTCAGCGGCACGCTTTTGT GGCGTCACTGCACTGTTACCCCGCCCTACGTGTCTCTGACGCTGACACCTTCTCACTGTGAAACGTCGCGACCTGTGACGTCTGGGGGGC GCCTCAAATCTTCCACTCCAGCATCGGATCCCGGAAAGGCAGCGTCGGAGACTGGACCCAAAACTCTTCCTGTTCTGCCTGCAGAGTTGA GCCCCGTCCGGGTCCTGGACCCGCGTAGTACTGACCCTGGATCCCTGTTCACTGCGTTCTCGCTCCCCGCGCTCCCTGCTGGACCCCGGG ATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGAGGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCC ATCTTGGATGCCTACATCATCAATGAAGAAGCAGTACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAG CATTCAATGGGAATGCACTCATACGATCTGGGCATGAACCACCTGGGAGACATGGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTG GGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATAT GGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCC TACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAA GATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGT GTCTACTATGAACCATCCTGTACTCAGAATGTGAATCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTT GTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGAAGGATATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTT CCCTCTTACCCAGAAATCTAGAGGATCTCTCCTTTTTATAACAAATCAAGAAATATGAAGCACTTTCTCTTAACTTAATTTTTCCTGCTG TATCCAGAAGAAATAATTGTGTCATGATTAATGTGTATTTACTGTACTAATTAGAAAATATAGTTTGAGGCCGGGCACGGTGGCTCACGC CTGTAATCCCAGTACTTGGGAGGCCAAGGCAGGCATATCAACTTGAGGCCAGGAGTTAAAGAGCAGCCTGGCTAACATGGTGAAACCCCA TCTCTACTAAAAATACAAAAAATTAGCCGAGCACGGTGGTGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCACGAGATTCCTTG AACCCAAGAGGTTGAGGCTATGTTGAGCTGAGATCACACCACTGTACTCCAGCCTGGATGACAGAGTGGAGACTCTGTTTCAAAAAAACA >In-frame_RRNAD1_ENST00000524343_chr1_156699007_+_CTSS_ENST00000368985_chr1_150730456_-_3976nt AAGGCAGCGTCGGAGACTGGACCCAAAACTCTTCCTGTTCTGCCTGCAGAGTTGAGCCCCGTCCGGGTCCTGGACCCGCGTAGTACTGAC CCTGGATCCCTGTTCACTGCGTTCTCGCTCCCCGCGCTCCCTGCTGGACCCCGGGATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGA GGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCCATCTTGGATGCCTACATCATCAATGAAGAAGCAGT ACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACTCATACGATCTGGGCAT GAACCACCTGGGAGACATGACCAGTGAAGAAGTGATGTCTTTGATGAGTTCCCTGAGAGTTCCCAGCCAGTGGCAGAGAAATATCACATA TAAGTCAAACCCTAATCGGATATTGCCTGATTCTGTGGACTGGAGAGAGAAAGGGTGTGTTACTGAAGTGAAATATCAAGGTTCTTGTGG TGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGGAAAGCTGGTGTCTCTCAGTGCCCAGAACCT GGTGGATTGCTCAACTGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATGACAACGGCTTTCCAGTACATCATTGATAACAAGGG CATCGACTCAGACGCTTCCTATCCCTACAAAGCCATGGATCAGAAATGTCAATATGACTCAAAATATCGTGCTGCCACATGTTCAAAGTA CACTGAACTTCCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCCAGTGTCTGTTGGTGTAGATGCGCGTCATCC TTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGTACTCAGAATGTGAATCATGGTGTACTTGTGGTTGGCTATGGTGA TCTTAATGGGAAAGAATACTGGCTTGTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGAAGGATATATTCGGATGGCAAGAAATAAAGG AAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTCTCCTTTTTATAACAAATCAAGAAATATGAAGCACTT TCTCTTAACTTAATTTTTCCTGCTGTATCCAGAAGAAATAATTGTGTCATGATTAATGTGTATTTACTGTACTAATTAGAAAATATAGTT TGAGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGTACTTGGGAGGCCAAGGCAGGCATATCAACTTGAGGCCAGGAGTTAAAGAGCA GCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCGAGCACGGTGGTGCATGCCTGTAATCCCAGCTACTTG GGAGGCTGAGGCACGAGATTCCTTGAACCCAAGAGGTTGAGGCTATGTTGAGCTGAGATCACACCACTGTACTCCAGCCTGGATGACAGA GTGGAGACTCTGTTTCAAAAAAACAGAAAAGAAAATATAGTTTGATTCTTCATTTTTTTAAATTTGCAAATCTCAGGATAAAGTTTGCTA AGTAAATTAGTAATGTACTATAGATATAACTGTACAAAAATTGTTCAACCTAAAACAATCTGTAATTGCTTATTGTTTTATTGTATACTC TTTGTCTTTTTAAGACCCCTAATAGCCTTTTGTAACTTGATGGCTTAAAAATACTTAATAAATCTGCCATTTCAAATTTCTATCATTGCC ACATACCATTCTTATTCCTAGGCAACTATTAATAATCTATCCTGAGAATATTAATTGTGGTATTCTGGTGATGGGGTTTAGCAACTTTGA TGGAAGAAAATATTAGGCTATAAATGTCCTAAGGACTCAGATTGTATCTTTGTACAGAAGAGGATTCAAAACGCCACGTGTAGTGGCTCA TGCCTGTAATCCCAACACTTTGGGAGGCTGAAGTAGGAGGATCGTCTTGAGCCCAGGAGTTCAAGACCAGCCTGGACAACATAGTGAGAC CTTGTCTCCACAAAAATAAAAAAGAAACTATCCAGGAGTGGTGGTGTGTGCCTGTGGTCCCTGCTATGCAGATGTCTAAGACAGGAGGAT CACAAGAGCCCAGGAGGTTGAGAATGCAGTGAGCTTGTAATTGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCTGTCTTAAA AAAAGAGGATTCAACACATATTTTTATATTATGTTAAAGTAAAGAAATGCATAAAAGACAAGCACTTTGGAAGAATTATTTTAATGATCA ACAATTTAATGTATTAGTCCAAATTATTTTTACGTAGTCATCAACAATTTGACCAGGGCCTTTATTTGGCAAATAACTGAGCCAACCAGA ATAAAATAACCAATACTCCACTGCTCATATTTTTATCTAATTCAGATGGATCTTCCTTACAACTGCTCTAGATTAGTAGATGCATCTAAG CAGGCAGCAGGAACTTTAAATTTTTTAAGTTCATGTCTATGACATGAACAATGTGTGGGATAATGTCATTAATATATCCTAAATTAACCT AAACGTATTTCACTAACTCTGGCTCCTTCTCCATAAAGCACATTTTAAGGAACAAGAATTGCTAAATATAAAAACATAAATAATACCATA ATACATGGCTATCATCAAAAGTGTATAGAATATTATAGTTTAAAAGTATTTAGTTGATTACTTTTCAGTTTTGTTTTGTTTTTTGAGACG GAGTCTCACTCTGTTGCCCAGGCTGGAGTGCAGTGGCACCATCTCAGTTCACTGCAACTTCTGCCTCCCGAGTTCAAGCGATTCTCCTGC CTCAGCCTCCCGAGTAGCTGGAATTATAGGCGTGCACCACCACGCCCAGCTAATTTTTGTATTTTTAGTAAAGACAGGGTTTTGCCACAT TAGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCCACCCCAGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCACTGAGC CCAGCCTACTTTTCAGTTTTTAACATAATTTTTGTTTTATCCACAACTTTTCAAGTATTGAAAGTAGAATAAAAACATGGGTTCTTAGTC TTTAGCTATCTGTTAAAGCCTATGAATGCCTTCTTAAAATCATGTTTTTAAATGCATAAAATATATAGGATTACAAAGGAATCTAATTAT ATCGAAATACAGTTATTAAAATGTTAAAAGATAAGTTTGTTATATATTAATATGCATGCTTCTTTATAAATGCATTAAATAAGAGTTAAT AGCTATCCTAAATTTGAAATAGTGATAAGCATAATGAAAATAGATGCAAAAAACTAATGTGATATGAAAATATCTGGGTTTTTCTTTTGA TGATGAAGTATTGCTAATATTACCGTGGTTTATGAACTATGTTCAGAATTGAAGAAAATCCTAACTTTCAGTTAGAGGTTAGTGACGGGG TTCAGGACACCCTACACAAAATACAGCACTTTGACATATTGAATATTTTAAGCTGAAGGCATTTGAGGAAATTGCAGAAGCAGGAAGGTG ACTCTGACCTTCTGCCTGCTGTTCTCCCCAGAAGCAGCCATAAAACCTGGGAAGGATTTTCTGACCTTCCCCTGAAGTAGATCATAAGAC TGTCATGTAAGAGGTGCTCTCCTGGCACCCAGAGAAAAGGAGCATCCTTACCTCCAAAAGCACAGGGACACAAAGAGGAATCTAAACAAA CAGGCCTCTCAGTTTCCCCCAGTTTATTACATTTAGCTTGTTCACACTTTGCCCTATGACATTTCTACATCACTGGCTGCTCTTCATCAA ACCTACTATAAAAAACATTCAAGTTCAACTGTTTCTTTGGGCCTTTATTTCCTTATGGAGCCCCTCGTGTCGTGTAAAACTTATATTAAA >In-frame_RRNAD1_ENST00000524343_chr1_156699007_+_CTSS_ENST00000448301_chr1_150730456_-_1455nt AAGGCAGCGTCGGAGACTGGACCCAAAACTCTTCCTGTTCTGCCTGCAGAGTTGAGCCCCGTCCGGGTCCTGGACCCGCGTAGTACTGAC CCTGGATCCCTGTTCACTGCGTTCTCGCTCCCCGCGCTCCCTGCTGGACCCCGGGATGCCGGGCATCTCCGCCCGAGGCCTCTCTCATGA GGGGAGGAAGCAGCTAGCTGTTAACCTCACCCGTGTCCTGGCACTCTACCGTTCCATCTTGGATGCCTACATCATCAATGAAGAAGCAGT ACGACGTCTCATCTGGGAAAAGAATCTAAAGTTTGTGATGCTTCACAACCTGGAGCATTCAATGGGAATGCACTCATACGATCTGGGCAT GAACCACCTGGGAGACATGGGTTCTTGTGGTGCTTGCTGGGCTTTCAGTGCTGTGGGGGCCCTGGAAGCACAGCTGAAGCTGAAAACAGG AAAGCTGGTGTCTCTCAGTGCCCAGAACCTGGTGGATTGCTCAACTGAAAAATATGGAAACAAAGGCTGCAATGGTGGCTTCATGACAAC GGCTTTCCAGTACATCATTGATAACAAGGGCATCGACTCAGACGCTTCCTATCCCTACAAAGCCATGGATCAGAAATGTCAATATGACTC AAAATATCGTGCTGCCACATGTTCAAAGTACACTGAACTTCCTTATGGCAGAGAAGATGTCCTGAAAGAAGCTGTGGCCAATAAAGGCCC AGTGTCTGTTGGTGTAGATGCGCGTCATCCTTCTTTCTTCCTCTACAGAAGTGGTGTCTACTATGAACCATCCTGTACTCAGAATGTGAA TCATGGTGTACTTGTGGTTGGCTATGGTGATCTTAATGGGAAAGAATACTGGCTTGTGAAAAACAGCTGGGGCCACAACTTTGGTGAAGA AGGATATATTCGGATGGCAAGAAATAAAGGAAATCATTGTGGGATTGCTAGCTTTCCCTCTTACCCAGAAATCTAGAGGATCTCTCCTTT TTATAACAAATCAAGAAATATGAAGCACTTTCTCTTAACTTAATTTTTCCTGCTGTATCCAGAAGAAATAATTGTGTCATGATTAATGTG TATTTACTGTACTAATTAGAAAATATAGTTTGAGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGTACTTGGGAGGCCAAGGCAGGCA TATCAACTTGAGGCCAGGAGTTAAAGAGCAGCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCCGAGCACG GTGGTGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCACGAGATTCCTTGAACCCAAGAGGTTGAGGCTATGTTGAGCTGAGATC ACACCACTGTACTCCAGCCTGGATGACAGAGTGGAGACTCTGTTTCAAAAAAACAGAAAAGAAAATATAGTTTGATTCTTCATTTTTTTA |
Top |
FusionGenePPI for RRNAD1_CTSS |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RRNAD1 | ELAVL1 | CTSS | SERPINB3, CST5, IRF2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for RRNAD1_CTSS |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for RRNAD1_CTSS |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CTSS | C0011616 | Contact Dermatitis | 1 | CTD_human |
| Tgene | CTSS | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | CTSS | C0027626 | Neoplasm Invasiveness | 1 | CTD_human |
| Tgene | CTSS | C0028754 | Obesity | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|