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Fusion gene ID: 32024 |
FusionGeneSummary for RPRD1A_CHMP2B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RPRD1A_CHMP2B | Fusion gene ID: 32024 | Hgene | Tgene | Gene symbol | RPRD1A | CHMP2B | Gene ID | 55197 | 25978 |
| Gene name | regulation of nuclear pre-mRNA domain containing 1A | charged multivesicular body protein 2B | |
| Synonyms | HsT3101|P15RS | ALS17|CHMP2.5|DMT1|VPS2-2|VPS2B | |
| Cytomap | 18q12.2 | 3p11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | regulation of nuclear pre-mRNA domain-containing protein 1ACDKN2B-related proteinCyclin-dependent kinase inhibitor 2B-related protein (p15INK4B-related protein)cyclin-dependent kinase 2B-inhibitor-related proteinp15INK4B-related protein | charged multivesicular body protein 2bVPS2 homolog Bchromatin modifying protein 2Bvacuolar protein-sorting-associated protein 2-2 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q96P16 | Q9UQN3 | |
| Ensembl transtripts involved in fusion gene | ENST00000590898, ENST00000399022, ENST00000337059, ENST00000357384, ENST00000588737, ENST00000319040, ENST00000588459, | ENST00000471660, ENST00000263780, ENST00000494980, ENST00000472024, | |
| Fusion gene scores | * DoF score | 6 X 8 X 3=144 | 3 X 2 X 3=18 |
| # samples | 9 | 3 | |
| ** MAII score | log2(9/144*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: RPRD1A [Title/Abstract] AND CHMP2B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | CHMP2B | GO:0039702 | viral budding via host ESCRT complex | 24878737 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-AB2O-01A | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000590898 | ENST00000471660 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5UTR-3CDS | ENST00000590898 | ENST00000263780 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5UTR-3CDS | ENST00000590898 | ENST00000494980 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5UTR-3UTR | ENST00000590898 | ENST00000472024 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000399022 | ENST00000471660 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000399022 | ENST00000263780 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000399022 | ENST00000494980 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5CDS-3UTR | ENST00000399022 | ENST00000472024 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3CDS | ENST00000337059 | ENST00000471660 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3CDS | ENST00000337059 | ENST00000263780 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3CDS | ENST00000337059 | ENST00000494980 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3UTR | ENST00000337059 | ENST00000472024 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000357384 | ENST00000471660 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000357384 | ENST00000263780 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000357384 | ENST00000494980 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5CDS-3UTR | ENST00000357384 | ENST00000472024 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5UTR-3CDS | ENST00000588737 | ENST00000471660 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5UTR-3CDS | ENST00000588737 | ENST00000263780 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5UTR-3CDS | ENST00000588737 | ENST00000494980 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5UTR-3UTR | ENST00000588737 | ENST00000472024 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000319040 | ENST00000471660 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000319040 | ENST00000263780 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| In-frame | ENST00000319040 | ENST00000494980 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| 5CDS-3UTR | ENST00000319040 | ENST00000472024 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3CDS | ENST00000588459 | ENST00000471660 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3CDS | ENST00000588459 | ENST00000263780 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3CDS | ENST00000588459 | ENST00000494980 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
| intron-3UTR | ENST00000588459 | ENST00000472024 | RPRD1A | chr18 | 33647217 | - | CHMP2B | chr3 | 87294864 | + |
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FusionProtFeatures for RPRD1A_CHMP2B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RPRD1A | CHMP2B |
| Interacts with phosphorylated C-terminal heptapeptiderepeat domain (CTD) of the largest RNA polymerase II subunitPOLR2A, and participates in dephosphorylation of the CTD by RPAP2.May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E(CCNE1) in the cell cycle. {ECO:0000269|PubMed:22231121,ECO:0000269|PubMed:24399136, ECO:0000269|PubMed:24997600}. | Probable core component of the endosomal sortingrequired for transport complex III (ESCRT-III) which is involvedin multivesicular bodies (MVBs) formation and sorting of endosomalcargo proteins into MVBs. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from thelimiting membrane of the endosome and mostly are delivered tolysosomes enabling degradation of membrane proteins, such asstimulated growth factor receptors, lysosomal enzymes and lipids.The MVB pathway appears to require the sequential function ofESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostlydissociate from the invaginating membrane before the ILV isreleased. The ESCRT machinery also functions in topologicallyequivalent membrane fission events, such as the terminal stages ofcytokinesis and the budding of enveloped viruses (HIV-1 and otherlentiviruses). ESCRT-III proteins are believed to mediate thenecessary vesicle extrusion and/or membrane fission activities,possibly in conjunction with the AAA ATPase VPS4. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for RPRD1A_CHMP2B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_222aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCCKFKS YFYVYTNKSDEFPNEDGWSNVYYSKNNAGSXQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWN >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_222aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCCKFKS YFYVYTNKSDEFPNEDGWSNVYYSKNNAGSXQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWN >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_192aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCYNAGS XQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWNXNFWKDGQSSISCSKLTICLYFKGYNLRXR >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_222aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCCKFKS YFYVYTNKSDEFPNEDGWSNVYYSKNNAGSXQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWN >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_222aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCCKFKS YFYVYTNKSDEFPNEDGWSNVYYSKNNAGSXQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWN >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_192aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCYNAGS XQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWNXNFWKDGQSSISCSKLTICLYFKGYNLRXR >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_222aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCCKFKS YFYVYTNKSDEFPNEDGWSNVYYSKNNAGSXQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWN >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_222aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCCKFKS YFYVYTNKSDEFPNEDGWSNVYYSKNNAGSXQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWN >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_192aa MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKGIRNXENGQDWXXGSLQSFSQTTCASTETEDENFCYNAGS XQEDGSTKDITNNAEFPEGKHENGNDXRNDQXYTXXHLXRFXXRRRKPGYCESSSXXNWNXNFWKDGQSSISCSKLTICLYFKGYNLRXR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_667nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGT TACTTCTATGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_667nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGT TACTTCTATGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_577nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_667nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGT TACTTCTATGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_667nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGT TACTTCTATGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_577nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_667nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGT TACTTCTATGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_667nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGT TACTTCTATGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_577nt ATGTCAGCCTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTC ATTCACCACCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGAT TGGTAATAAGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTACAATGCAGGCAGT TAACAAGAAGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGAT CAATGATACACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAAT TGAAATTTCTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_931nt ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATA AGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGTTACTTCTA TGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGTTAACAAGA AGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATA CACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTT CTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAAC GGCAACTCAAGGCTTTAGGAGTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGC >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_2565nt ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATA AGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGTTACTTCTA TGTCTACACAAACAAAAGTGATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGTTAACAAGA AGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATA CACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTT CTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAAC GGCAACTCAAGGCTTTAGGAGTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGC AGATTTCTTTTACAAAACACATGTATTTTGCAAAAAAAAAAAAAATGAAGACCATGAGTGAACAGTTGTTTCCTAACCCATGGCTATTTA GAATCTTTTGCCAAAGAATGACAATGATGCAAAAATGGGAACAGTTTGGATTTTAATTAGAACTGTTTAGGAGTGATGATGTGTAAAAAG TTGACTTCTCTTTTGCATGGCACAGAGAAATTATATTCCTTACTTCATGTCAGTTTATGTTCTAAATCTTTTTCACTGAATATAAAAATC TTGTTAAATGCCATTAGGCACCAACTTAAAGAGGGTTGTAAAAATATTAAAAGTATATCGTTAATTCTGTATCTGTTGCTTGTCTTTTGT AAGTGATTATGTGTTATGACCATAGGTGGTTACAGCTGCCAAATTATTTTTAAATGGTCAAAAAGAAGAGTGCTATTTAAACATCTGTCT TAAACAAAAACTGTCATAACTTTTCTTTTTTCTTTTTCCATTAGGAGAACATTCTAGTTGGTAAATTTCAAAATGTGCTTGACACCTGCC TTAAATAGCACAGACCTATTGTGCACATCTTTAAATTATTTCAGCTGGCAGAAAAGAATTACATTTAAAACTGAAATCAAGGCCTCAATA CAAAGATTATCCTGGCTCTTTTCTATCTCTGTGGGCCTAATTGAAATATGTACTCTTATTTTAGACACGCCTCTGTTAAAACAGACCAGG TTTTCCTGGTCTCAGACCTATGATGACTTGTCCCTTTGATGTCACTACTGTGAATTGAATATAATTAGTAAAAATAGACGATGAATAAAT AACACTTTATAGTAAGAAAACAATATATTTTGGCCATCTAAAAATGAGAATTATAATTATATGAATTATAATTTAAACTGTTTAATTTTG TTTAATGTGTATATTGAATCTTCCAAATTGAAGCCATTATTCTCAATTAAGTACTACAACTATGACAATGCTTGACCTACATTTCTAAAA TAAAAATTCACATTTTTTGATAAATAAACTACAGTTTTACCAGAAATTACTATCTAAATGTGTATTAGCAGTATTTTTTAAGGTGAAATT GCCTTGGTATCTAATGAATGTGTAGACAGGGAGATAAAATGAAGGATTGCCAGACTAGTTAGAATAGAATTTAGGATTAGGTTAGTTTTG AAAAATGATGTTGTAATATATGGGTTCTAACACATCCTACCATAAAAACTGGAGGAGATATGTGTAACCTGGTTAATTTGGGATGGTGGA CATTTTGGGCTAATACTGACAAAATACATCTTAGGACTAGTATACATGTGACACGGATTGCTAGGAGGAATGAAAAACTAAACTGTATAG TTTATATTCCGTAAACCATTTTATAATGTTCAAAGATTAGGTTTTGTTATTGATAGTATTAAATACACAGTTTCTCTTAACAGTGATGGG TGAAAACATTTTACCGGATTATGGAATGTTTACCAGAACATGTTTTGATTCTTGAATGTACATAATAATGCCATCTAACTTATTTACGTT CTTGTTTACATGTGGGAGCTTTTGTTTTCAAAAATTATTTTGTTAAAAAATCTCAATAAAGATTTATTATTGTTGTTCTTTTCTTACCTT >In-frame_RPRD1A_ENST00000399022_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_853nt ACTGCCGGCCGGACGCCATCTTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGG GGGCGAGGCCGCAGCTAGGGCGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGC CTTCTCTGAGGCGGCGCTGGAGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCA CCGTAAACACTCGCGTCCCATCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATA AGGAAGCTTGCAAAGTTTTAGCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTACAATGCAGGCAGTTAACAAGA AGATGGATCCACAAAAGACATTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATA CACTTGATGACATCTTTGACGGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTT CTGGAAAGATGGCCAAAGCTCCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAAC GGCAACTCAAGGCTTTAGGAGTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGC >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_911nt TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATAAGGAAGCTTGCAAAGTTTTA GCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGTTACTTCTATGTCTACACAAACAAAAGTG ATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGTTAACAAGAAGATGGATCCACAAAAGACA TTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATACACTTGATGACATCTTTGAC GGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTTCTGGAAAGATGGCCAAAGCT CCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAACGGCAACTCAAGGCTTTAGGA GTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGCAGATTTCTTTTACAAAACAC >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_2545nt TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATAAGGAAGCTTGCAAAGTTTTA GCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGTTACTTCTATGTCTACACAAACAAAAGTG ATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGTTAACAAGAAGATGGATCCACAAAAGACA TTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATACACTTGATGACATCTTTGAC GGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTTCTGGAAAGATGGCCAAAGCT CCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAACGGCAACTCAAGGCTTTAGGA GTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGCAGATTTCTTTTACAAAACAC ATGTATTTTGCAAAAAAAAAAAAAATGAAGACCATGAGTGAACAGTTGTTTCCTAACCCATGGCTATTTAGAATCTTTTGCCAAAGAATG ACAATGATGCAAAAATGGGAACAGTTTGGATTTTAATTAGAACTGTTTAGGAGTGATGATGTGTAAAAAGTTGACTTCTCTTTTGCATGG CACAGAGAAATTATATTCCTTACTTCATGTCAGTTTATGTTCTAAATCTTTTTCACTGAATATAAAAATCTTGTTAAATGCCATTAGGCA CCAACTTAAAGAGGGTTGTAAAAATATTAAAAGTATATCGTTAATTCTGTATCTGTTGCTTGTCTTTTGTAAGTGATTATGTGTTATGAC CATAGGTGGTTACAGCTGCCAAATTATTTTTAAATGGTCAAAAAGAAGAGTGCTATTTAAACATCTGTCTTAAACAAAAACTGTCATAAC TTTTCTTTTTTCTTTTTCCATTAGGAGAACATTCTAGTTGGTAAATTTCAAAATGTGCTTGACACCTGCCTTAAATAGCACAGACCTATT GTGCACATCTTTAAATTATTTCAGCTGGCAGAAAAGAATTACATTTAAAACTGAAATCAAGGCCTCAATACAAAGATTATCCTGGCTCTT TTCTATCTCTGTGGGCCTAATTGAAATATGTACTCTTATTTTAGACACGCCTCTGTTAAAACAGACCAGGTTTTCCTGGTCTCAGACCTA TGATGACTTGTCCCTTTGATGTCACTACTGTGAATTGAATATAATTAGTAAAAATAGACGATGAATAAATAACACTTTATAGTAAGAAAA CAATATATTTTGGCCATCTAAAAATGAGAATTATAATTATATGAATTATAATTTAAACTGTTTAATTTTGTTTAATGTGTATATTGAATC TTCCAAATTGAAGCCATTATTCTCAATTAAGTACTACAACTATGACAATGCTTGACCTACATTTCTAAAATAAAAATTCACATTTTTTGA TAAATAAACTACAGTTTTACCAGAAATTACTATCTAAATGTGTATTAGCAGTATTTTTTAAGGTGAAATTGCCTTGGTATCTAATGAATG TGTAGACAGGGAGATAAAATGAAGGATTGCCAGACTAGTTAGAATAGAATTTAGGATTAGGTTAGTTTTGAAAAATGATGTTGTAATATA TGGGTTCTAACACATCCTACCATAAAAACTGGAGGAGATATGTGTAACCTGGTTAATTTGGGATGGTGGACATTTTGGGCTAATACTGAC AAAATACATCTTAGGACTAGTATACATGTGACACGGATTGCTAGGAGGAATGAAAAACTAAACTGTATAGTTTATATTCCGTAAACCATT TTATAATGTTCAAAGATTAGGTTTTGTTATTGATAGTATTAAATACACAGTTTCTCTTAACAGTGATGGGTGAAAACATTTTACCGGATT ATGGAATGTTTACCAGAACATGTTTTGATTCTTGAATGTACATAATAATGCCATCTAACTTATTTACGTTCTTGTTTACATGTGGGAGCT TTTGTTTTCAAAAATTATTTTGTTAAAAAATCTCAATAAAGATTTATTATTGTTGTTCTTTTCTTACCTTTTTTGCTCTTTTTGGTTCCT >In-frame_RPRD1A_ENST00000357384_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_833nt TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATAAGGAAGCTTGCAAAGTTTTA GCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTACAATGCAGGCAGTTAACAAGAAGATGGATCCACAAAAGACA TTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATACACTTGATGACATCTTTGAC GGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTTCTGGAAAGATGGCCAAAGCT CCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAACGGCAACTCAAGGCTTTAGGA GTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGCAGATTTCTTTTACAAAACAC >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000471660_chr3_87294864_+_911nt TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATAAGGAAGCTTGCAAAGTTTTA GCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGTTACTTCTATGTCTACACAAACAAAAGTG ATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGTTAACAAGAAGATGGATCCACAAAAGACA TTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATACACTTGATGACATCTTTGAC GGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTTCTGGAAAGATGGCCAAAGCT CCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAACGGCAACTCAAGGCTTTAGGA GTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGCAGATTTCTTTTACAAAACAC >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000263780_chr3_87294864_+_2545nt TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATAAGGAAGCTTGCAAAGTTTTA GCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTGTAAGTTCAAAAGTTACTTCTATGTCTACACAAACAAAAGTG ATGAATTCCCAAATGAAGATGGCTGGAGCAATGTCTACTACAGCAAAAACAATGCAGGCAGTTAACAAGAAGATGGATCCACAAAAGACA TTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATACACTTGATGACATCTTTGAC GGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTTCTGGAAAGATGGCCAAAGCT CCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAACGGCAACTCAAGGCTTTAGGA GTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGCAGATTTCTTTTACAAAACAC ATGTATTTTGCAAAAAAAAAAAAAATGAAGACCATGAGTGAACAGTTGTTTCCTAACCCATGGCTATTTAGAATCTTTTGCCAAAGAATG ACAATGATGCAAAAATGGGAACAGTTTGGATTTTAATTAGAACTGTTTAGGAGTGATGATGTGTAAAAAGTTGACTTCTCTTTTGCATGG CACAGAGAAATTATATTCCTTACTTCATGTCAGTTTATGTTCTAAATCTTTTTCACTGAATATAAAAATCTTGTTAAATGCCATTAGGCA CCAACTTAAAGAGGGTTGTAAAAATATTAAAAGTATATCGTTAATTCTGTATCTGTTGCTTGTCTTTTGTAAGTGATTATGTGTTATGAC CATAGGTGGTTACAGCTGCCAAATTATTTTTAAATGGTCAAAAAGAAGAGTGCTATTTAAACATCTGTCTTAAACAAAAACTGTCATAAC TTTTCTTTTTTCTTTTTCCATTAGGAGAACATTCTAGTTGGTAAATTTCAAAATGTGCTTGACACCTGCCTTAAATAGCACAGACCTATT GTGCACATCTTTAAATTATTTCAGCTGGCAGAAAAGAATTACATTTAAAACTGAAATCAAGGCCTCAATACAAAGATTATCCTGGCTCTT TTCTATCTCTGTGGGCCTAATTGAAATATGTACTCTTATTTTAGACACGCCTCTGTTAAAACAGACCAGGTTTTCCTGGTCTCAGACCTA TGATGACTTGTCCCTTTGATGTCACTACTGTGAATTGAATATAATTAGTAAAAATAGACGATGAATAAATAACACTTTATAGTAAGAAAA CAATATATTTTGGCCATCTAAAAATGAGAATTATAATTATATGAATTATAATTTAAACTGTTTAATTTTGTTTAATGTGTATATTGAATC TTCCAAATTGAAGCCATTATTCTCAATTAAGTACTACAACTATGACAATGCTTGACCTACATTTCTAAAATAAAAATTCACATTTTTTGA TAAATAAACTACAGTTTTACCAGAAATTACTATCTAAATGTGTATTAGCAGTATTTTTTAAGGTGAAATTGCCTTGGTATCTAATGAATG TGTAGACAGGGAGATAAAATGAAGGATTGCCAGACTAGTTAGAATAGAATTTAGGATTAGGTTAGTTTTGAAAAATGATGTTGTAATATA TGGGTTCTAACACATCCTACCATAAAAACTGGAGGAGATATGTGTAACCTGGTTAATTTGGGATGGTGGACATTTTGGGCTAATACTGAC AAAATACATCTTAGGACTAGTATACATGTGACACGGATTGCTAGGAGGAATGAAAAACTAAACTGTATAGTTTATATTCCGTAAACCATT TTATAATGTTCAAAGATTAGGTTTTGTTATTGATAGTATTAAATACACAGTTTCTCTTAACAGTGATGGGTGAAAACATTTTACCGGATT ATGGAATGTTTACCAGAACATGTTTTGATTCTTGAATGTACATAATAATGCCATCTAACTTATTTACGTTCTTGTTTACATGTGGGAGCT TTTGTTTTCAAAAATTATTTTGTTAAAAAATCTCAATAAAGATTTATTATTGTTGTTCTTTTCTTACCTTTTTTGCTCTTTTTGGTTCCT >In-frame_RPRD1A_ENST00000319040_chr18_33647217_-_CHMP2B_ENST00000494980_chr3_87294864_+_833nt TTGCTGGTTTGCGGCCGGTCTTGGATGAAGCGGCGGCCGTGGTGAGAGCGTGGGGAAGGGTGGGGTGAGGGGGCGAGGCCGCAGCTAGGG CGGCGAAACTCTCCTCCCCTCGGCCCCACCGCGTGGGACGGCGTGAACGTGGTGTCGGAGGGATGTCAGCCTTCTCTGAGGCGGCGCTGG AGAAGAAGCTGTCGGAGTTGAGCAACTCGCAGCAGAGCGTGCAGACCTTGTCCCTGTGGCTCATTCACCACCGTAAACACTCGCGTCCCA TCGTCACCGTGTGGGAGCGGGAGCTGCGGAAAGGAATTAGAAATTAAGAAAATGGCCAAGATTGGTAATAAGGAAGCTTGCAAAGTTTTA GCCAAACAACTTGTGCATCTACGGAAACAGAAGACGAGAACTTTTGCTACAATGCAGGCAGTTAACAAGAAGATGGATCCACAAAAGACA TTACAAACAATGCAGAATTTCCAGAAGGAAAACATGAAAATGGAAATGACTGAAGAAATGATCAATGATACACTTGATGACATCTTTGAC GGTTCTGATGACGAAGAAGAAAGCCAGGATATTGTGAATCAAGTTCTTGATGAAATTGGAATTGAAATTTCTGGAAAGATGGCCAAAGCT CCATCAGCTGCTCGAAGCTTACCATCTGCCTCTACTTCAAAGGCTACAATCTCAGATGAAGAGATTGAACGGCAACTCAAGGCTTTAGGA GTAGATTAGTCAAAAGAAGTCATACTATTTTGCTTACTTATAATTATGTAGTATAAACCAAGCACAGTGCAGATTTCTTTTACAAAACAC |
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FusionGenePPI for RPRD1A_CHMP2B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RPRD1A | ELAVL1, BRCA1, BCAR3, YWHAZ, RIOK2, KDM1A, ANKMY2, HSF1, NPLOC4, PLIN3, ACTR2, FNTB, MCMBP, PARP6, SRP9, STAT5B, SURF2, TTLL12, WWOX, TP53, KPNA3, MOV10, NXF1, EGFR, GPN3, RPRD1B, POLR2M, CYP1A1, POLR2G, DPH2, DXO, MITD1, CCDC22, SH3GLB1, VPS37B, EWSR1, POU5F1, LMO2, POLR2D, ASB6, SNRNP27, GTF2E2, MRPS11, FGB, USP47, PITHD1, MAX, ARNTL, HAUS6, PHLDB3, PTRF, PHF21A, OIP5, CCDC93, CCDC132, HMG20A, RCOR1, GRIPAP1, DZIP3, VPS53, PSMD9, CLOCK, RABGAP1L, GOLGA5, TUFT1, YEATS4, CCHCR1, TFPT, NCKAP5L, PKN3, GIT2, NUF2, THAP11, RABGEF1, JUN, VPS51 | CHMP2B | TRAF2, VHL, ATP5C1, SQSTM1, TERF2IP, USP8, USP54, CHMP2B, CHMP3, PNMA1, PHGDH, MALSU1, ATP6V1B1, CHMP2A, PAFAH1B1, CHMP4B, XPO1, MAD2L1, RAB5C, RAB7A, ATP6AP2, LTN1, GOLT1B, MYH14, SGOL1, CDH1, TMEM106B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RPRD1A_CHMP2B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RPRD1A_CHMP2B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | CHMP2B | C1836076 | Amyotrophic Lateral Sclerosis, Chmp2B-Related | 2 | UNIPROT |
| Tgene | CHMP2B | C0002736 | Amyotrophic Lateral Sclerosis | 1 | CTD_human;HPO;ORPHANET |
| Tgene | CHMP2B | C0338451 | Frontotemporal dementia | 1 | CTD_human;HPO |
| Tgene | CHMP2B | C0751072 | Frontotemporal Lobar Degeneration | 1 | CTD_human |
| Tgene | CHMP2B | C1833296 | FRONTOTEMPORAL DEMENTIA, CHROMOSOME 3-LINKED | 1 | CTD_human;UNIPROT |
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