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Fusion gene ID: 31891 |
FusionGeneSummary for RPL34_IQCJ |
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Fusion gene information | Fusion gene name: RPL34_IQCJ | Fusion gene ID: 31891 | Hgene | Tgene | Gene symbol | RPL34 | IQCJ | Gene ID | 6164 | 654502 |
Gene name | ribosomal protein L34 | IQ motif containing J | |
Synonyms | L34 | - | |
Cytomap | 4q25 | 3q25.32 | |
Type of gene | protein-coding | protein-coding | |
Description | 60S ribosomal protein L34large ribosomal subunit protein eL34leukemia-associated protein | IQ domain-containing protein Jcalmodulin binding protein | |
Modification date | 20180522 | 20180329 | |
UniProtAcc | P49207 | Q1A5X6 | |
Ensembl transtripts involved in fusion gene | ENST00000394667, ENST00000502534, ENST00000394665, ENST00000506397, ENST00000394668, | ENST00000481796, ENST00000397832, ENST00000451172, ENST00000482126, | |
Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 1 X 1 X 1=1 |
# samples | 4 | 1 | |
** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: RPL34 [Title/Abstract] AND IQCJ [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AA954224 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-intron | ENST00000394667 | ENST00000481796 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394667 | ENST00000397832 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394667 | ENST00000451172 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394667 | ENST00000482126 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000502534 | ENST00000481796 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000502534 | ENST00000397832 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000502534 | ENST00000451172 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000502534 | ENST00000482126 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394665 | ENST00000481796 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394665 | ENST00000397832 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394665 | ENST00000451172 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394665 | ENST00000482126 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000506397 | ENST00000481796 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000506397 | ENST00000397832 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000506397 | ENST00000451172 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000506397 | ENST00000482126 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394668 | ENST00000481796 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394668 | ENST00000397832 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394668 | ENST00000451172 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
5CDS-intron | ENST00000394668 | ENST00000482126 | RPL34 | chr4 | 109543745 | - | IQCJ | chr3 | 158826991 | - |
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FusionProtFeatures for RPL34_IQCJ |
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Hgene | Tgene |
RPL34 | IQCJ |
Component of the large ribosomal subunit.{ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:25901680,ECO:0000269|PubMed:25957688, ECO:0000305|PubMed:12962325}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for RPL34_IQCJ |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for RPL34_IQCJ |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RPL34_IQCJ |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RPL34_IQCJ |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |