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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 31696

FusionGeneSummary for ROCK2_BTNL2

check button Fusion gene summary
Fusion gene informationFusion gene name: ROCK2_BTNL2
Fusion gene ID: 31696
HgeneTgene
Gene symbol

ROCK2

BTNL2

Gene ID

9475

56244

Gene nameRho associated coiled-coil containing protein kinase 2butyrophilin like 2
SynonymsROCK-IIBTL-II|BTN7|HSBLMHC1|SS2
Cytomap

2p25.1

6p21.32

Type of geneprotein-codingprotein-coding
Descriptionrho-associated protein kinase 2p164 ROCK-2rho-associated, coiled-coil-containing protein kinase IIbutyrophilin-like protein 2butyrophilin-like 2 (MHC class II associated)truncated BTNL2
Modification date2018052720180523
UniProtAcc

O75116

Q9UIR0

Ensembl transtripts involved in fusion geneENST00000315872, ENST00000462366, 
ENST00000401753, 		ENST00000454136, 
ENST00000374995, ENST00000540315, 
ENST00000374993, ENST00000544175, 
ENST00000414363, ENST00000429232, 
ENST00000546948, ENST00000549631, 
ENST00000549560, ENST00000550327, 
ENST00000547901, ENST00000548922, 
ENST00000549943, ENST00000552479, 
ENST00000546419, ENST00000551095, 
ENST00000553032, ENST00000548832, 
ENST00000546521, ENST00000549852, 
ENST00000551471, ENST00000549081, 
ENST00000552394, ENST00000551868, 
ENST00000547502, ENST00000550698, 
ENST00000551101, ENST00000550531, 
ENST00000552523, ENST00000548066, 
ENST00000551409, ENST00000551686, 
ENST00000552970, ENST00000548717, 
ENST00000553068, ENST00000551561, 
ENST00000548835, ENST00000548253, 
ENST00000551669, ENST00000547429, 
Fusion gene scores* DoF score10 X 6 X 8=4801 X 1 X 1=1
# samples 101
** MAII scorelog2(10/480*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: ROCK2 [Title/Abstract] AND BTNL2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationKinase involved fusion gene, inframe and retained kinase domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneROCK2

GO:0006468

protein phosphorylation

18559669


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDOVTCGA-23-2077-01AROCK2chr2

11351807

-BTNL2chr6

32369582

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000315872ENST00000454136ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000374995ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000540315ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000374993ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-5UTRENST00000315872ENST00000544175ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-5UTRENST00000315872ENST00000414363ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000429232ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000546948ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000549631ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000549560ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000550327ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000547901ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000548922ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000549943ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000552479ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000546419ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551095ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000553032ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000548832ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000546521ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000549852ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551471ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000549081ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000552394ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551868ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000547502ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000550698ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551101ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000550531ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000552523ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000548066ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551409ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551686ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000552970ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000548717ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000553068ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551561ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000548835ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000548253ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000551669ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000315872ENST00000547429ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-3CDSENST00000462366ENST00000454136ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000374995ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000540315ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000374993ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-5UTRENST00000462366ENST00000544175ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-5UTRENST00000462366ENST00000414363ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000429232ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000546948ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000549631ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000549560ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000550327ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000547901ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000548922ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000549943ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000552479ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000546419ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551095ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000553032ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000548832ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000546521ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000549852ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551471ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000549081ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000552394ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551868ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000547502ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000550698ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551101ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000550531ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000552523ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000548066ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551409ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551686ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000552970ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000548717ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000553068ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551561ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000548835ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000548253ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000551669ROCK2chr2

11351807

-BTNL2chr6

32369582

-
intron-intronENST00000462366ENST00000547429ROCK2chr2

11351807

-BTNL2chr6

32369582

-
Frame-shiftENST00000401753ENST00000454136ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000374995ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000540315ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000374993ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-5UTRENST00000401753ENST00000544175ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-5UTRENST00000401753ENST00000414363ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000429232ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000546948ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000549631ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000549560ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000550327ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000547901ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000548922ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000549943ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000552479ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000546419ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551095ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000553032ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000548832ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000546521ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000549852ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551471ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000549081ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000552394ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551868ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000547502ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000550698ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551101ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000550531ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000552523ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000548066ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551409ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551686ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000552970ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000548717ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000553068ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551561ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000548835ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000548253ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000551669ROCK2chr2

11351807

-BTNL2chr6

32369582

-
5CDS-intronENST00000401753ENST00000547429ROCK2chr2

11351807

-BTNL2chr6

32369582

-

Top

FusionProtFeatures for ROCK2_BTNL2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ROCK2

O75116

BTNL2

Q9UIR0

Protein kinase which is a key regulator of actincytoskeleton and cell polarity. Involved in regulation of smoothmuscle contraction, actin cytoskeleton organization, stress fiberand focal adhesion formation, neurite retraction, cell adhesionand motility via phosphorylation of ADD1, BRCA2, CNN1, EZR,DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM.Phosphorylates SORL1 and IRF4. Acts as a negative regulator ofVEGF-induced angiogenic endothelial cell activation. Positivelyregulates the activation of p42/MAPK1-p44/MAPK3 and ofp90RSK/RPS6KA1 during myogenic differentiation. Plays an importantrole in the timely initiation of centrosome duplication. Inhibitskeratinocyte terminal differentiation. May regulate closure of theeyelids and ventral body wall through organization of actomyosinbundles. Plays a critical role in the regulation of spine andsynaptic properties in the hippocampus. Plays an important role ingenerating the circadian rhythm of the aortic myofilament Ca(2+)sensitivity and vascular contractility by modulating the myosinlight chain phosphorylation. {ECO:0000269|PubMed:10579722,ECO:0000269|PubMed:15699075, ECO:0000269|PubMed:16574662,ECO:0000269|PubMed:17015463, ECO:0000269|PubMed:19131646,ECO:0000269|PubMed:19997641, ECO:0000269|PubMed:21084279,ECO:0000269|PubMed:21147781}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-1833357_4257341389DomainNote=AGC-kinase C-terminal
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-1833497_5737341389DomainREM-1
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-183392_3547341389DomainProtein kinase
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-183398_1067341389Nucleotide bindingATP
TgeneBTNL2chr2:11351807chr6:32369582ENST00000374993-26236_355236456DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000414363-04142_23426246DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000414363-04236_35526246DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000414363-0429_14026246DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000544175-15142_234-41179DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000544175-15236_355-41179DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000544175-1529_140-41179DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548253-04142_2340246DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548253-04236_3550246DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548253-0429_1400246DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548717-05142_234-103179DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548717-05236_355-103179DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548717-0529_140-103179DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550327-06142_2340456DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550327-06236_3550456DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550327-0629_1400456DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550531-06142_2340456DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550531-06236_3550456DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550531-0629_1400456DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550698-05142_234-103179DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550698-05236_355-103179DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550698-0529_140-103179DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551095-06142_2340456DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551095-06236_3550456DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551095-0629_1400456DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551669-05142_234-103179DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551669-05236_355-103179DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551669-0529_140-103179DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551686-04142_2340246DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551686-04236_3550246DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551686-0429_1400246DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551868-04142_2340246DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551868-04236_3550246DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551868-0429_1400246DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000552479-06142_2340456DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000552479-06236_3550456DomainNote=Ig-like V-type 3
TgeneBTNL2chr2:11351807chr6:32369582ENST00000552479-0629_1400456DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000414363-0424_45526246Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000544175-151_6-41179Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000544175-1524_455-41179Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548253-041_60246Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548253-0424_4550246Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548717-051_6-103179Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548717-0524_455-103179Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550327-061_60456Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550327-0624_4550456Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550531-061_60456Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550531-0624_4550456Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550698-051_6-103179Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550698-0524_455-103179Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551095-061_60456Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551095-0624_4550456Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551669-051_6-103179Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551669-0524_455-103179Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551686-041_60246Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551686-0424_4550246Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551868-041_60246Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551868-0424_4550246Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000552479-061_60456Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000552479-0624_4550456Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000544175-157_23-41179TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548253-047_230246TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000548717-057_23-103179TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550327-067_230456TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550531-067_230456TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000550698-057_23-103179TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551095-067_230456TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551669-057_23-103179TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551686-047_230246TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000551868-047_230246TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000552479-067_230456TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-18331053_11317341389Coiled coilOntology_term=ECO:0000255
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-1833429_10247341389Coiled coilOntology_term=ECO:0000255
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-18331150_13497341389DomainPH
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-1833979_10477341389RegionRHOA binding
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-18331260_13157341389Zinc fingerPhorbol-ester/DAG-type
TgeneBTNL2chr2:11351807chr6:32369582ENST00000374993-26142_234236456DomainNote=Ig-like V-type 2
TgeneBTNL2chr2:11351807chr6:32369582ENST00000374993-2629_140236456DomainNote=Ig-like V-type 1
TgeneBTNL2chr2:11351807chr6:32369582ENST00000374993-261_6236456Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000374993-2624_455236456Topological domainExtracellular
TgeneBTNL2chr2:11351807chr6:32369582ENST00000414363-041_626246Topological domainCytoplasmic
TgeneBTNL2chr2:11351807chr6:32369582ENST00000374993-267_23236456TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneBTNL2chr2:11351807chr6:32369582ENST00000414363-047_2326246TransmembraneHelical%3B Signal-anchor for type II membrane protein


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FusionGeneSequence for ROCK2_BTNL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ROCK2_ENST00000315872_chr2_11351807_-_BTNL2_ENST00000454136_chr6_32369582_-_981aa
MSRPPPTGKMPGAPETAPGDGAGASRQRKLEALIRDPRSPINVESLLDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAE
DYDVVKVIGRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNL
MSNYDVPEKWAKFYTAEVVLALDAIHSMGLIHRDVKPDNMLLDKHGHLKLADFGTCMKMDETGMVHCDTAVGTPDYISPEVLKSQGGDGF
YGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLICAFLTDREVRLGRNGVEEIRQHPFFKNDQWH
WDNIRETAAPVVPELSSDIDSSNFDDIEDDKGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRETDSIQSRKNEESQEIQKKLY
TLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSVESALRQLEREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQL
EDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCLLETAKLKLEKEFINLQSALESE
RRDRTHGSEIINDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNK
IYESIEEAKSEAMKEKLQTELASLKVNGPSQPILVRVGEDIQLTCYLSPKANAQSMEVRWDRSHRYPAVHVYMDGDHVAGEQMAEYRGRT
VLVSDAIDEGRLTLQILSARPSDDGQYRCLFEKDDVYQEASLDLKVVSLGSSPLITVEGQEDGEMQPMCSSDGWFPQPHVPWRDMEGKTI


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ROCK2_ENST00000315872_chr2_11351807_-_BTNL2_ENST00000454136_chr6_32369582_-_2943nt
ATGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTG
GAGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGGATGGCTTAAATTCCTTGGTCCTTGATTTAGATTTTCCT
GCTTTGAGGAAAAACAAGAACATAGATAATTTCTTAAATAGATATGAGAAAATTGTGAAAAAAATCAGAGGTCTACAGATGAAGGCAGAA
GACTATGATGTTGTAAAAGTTATTGGAAGAGGTGCTTTTGGTGAAGTGCAGTTGGTTCGTCACAAGGCATCGCAGAAGGTTTATGCTATG
AAGCTTCTTAGTAAGTTTGAAATGATAAAAAGATCAGATTCTGCCTTTTTTTGGGAAGAAAGAGATATTATGGCCTTTGCCAATAGCCCC
TGGGTGGTTCAGCTTTTTTATGCCTTTCAAGATGATAGGTATCTGTACATGGTAATGGAGTACATGCCTGGTGGAGACCTTGTAAACCTT
ATGAGTAATTATGATGTGCCTGAAAAATGGGCCAAATTTTACACTGCTGAAGTTGTTCTTGCTCTGGATGCAATACACTCCATGGGTTTA
ATACACAGAGATGTGAAGCCTGACAACATGCTCTTGGATAAACATGGACATCTAAAATTAGCAGATTTTGGCACGTGTATGAAGATGGAT
GAAACAGGCATGGTACATTGTGATACAGCAGTTGGAACACCGGATTATATATCACCTGAGGTTCTGAAATCACAAGGGGGTGATGGTTTC
TATGGGCGAGAATGTGATTGGTGGTCTGTAGGTGTTTTCCTTTATGAGATGCTAGTGGGGGATACTCCATTTTATGCGGATTCACTTGTA
GGAACATATAGCAAAATTATGGATCATAAGAATTCACTGTGTTTCCCTGAAGATGCAGAAATTTCCAAACATGCAAAGAATCTCATCTGT
GCTTTCTTAACAGATAGGGAGGTACGACTTGGGAGAAATGGGGTGGAAGAAATCAGACAGCATCCTTTCTTTAAGAATGATCAGTGGCAT
TGGGATAACATAAGAGAAACGGCAGCTCCTGTAGTACCTGAACTCAGCAGTGACATAGACAGCAGCAATTTCGATGACATTGAAGATGAC
AAAGGAGATGTAGAAACCTTCCCAATTCCTAAAGCTTTTGTTGGAAATCAGCTGCCTTTCATCGGATTTACCTACTATAGAGAAAATTTA
TTATTAAGTGACTCTCCATCTTGTAGAGAAACTGATTCCATACAATCAAGGAAAAATGAAGAAAGTCAAGAGATTCAGAAAAAACTGTAT
ACATTAGAAGAACATCTTAGCAATGAGATGCAAGCCAAAGAGGAACTGGAACAGAAGTGCAAATCTGTTAATACTCGCCTAGAAAAAACA
GCAAAGGAGCTAGAAGAGGAGATTACCTTACGGAAAAGTGTGGAATCAGCATTAAGACAGTTAGAAAGAGAAAAGGCGCTTCTTCAGCAC
AAAAATGCAGAATATCAGAGGAAAGCTGATCATGAAGCAGACAAAAAACGAAATTTGGAAAATGATGTTAACAGCTTAAAAGATCAACTT
GAAGATTTGAAAAAAAGAAATCAAAACTCTCAAATATCCACTGAGAAAGTGAATCAACTCCAGAGACAACTGGATGAAACCAATGCTTTA
CTGCGAACAGAGTCTGATACTGCAGCCCGGTTAAGGAAAACCCAGGCAGAAAGTTCAAAACAGATTCAGCAGCTGGAATCTAACAATAGA
GATCTACAAGATAAAAACTGCCTGCTGGAGACTGCCAAGTTAAAACTTGAAAAGGAATTTATCAATCTTCAGTCAGCTCTAGAATCTGAA
AGGAGGGATCGAACCCATGGATCAGAGATAATTAATGATTTACAAGGTAGAATATGTGGCCTAGAAGAAGATTTAAAGAACGGCAAAATC
TTACTAGCGAAAGTAGAACTGGAGAAGAGACAACTTCAGGAGAGATTTACTGATTTGGAAAAGGAAAAAAGCAACATGGAAATAGATATG
ACATACCAACTAAAAGTTATACAGCAGAGCCTAGAACAAGAAGAAGCTGAACATAAGGCCACAAAGGCACGACTAGCAGATAAAAATAAG
ATCTATGAGTCCATCGAAGAAGCCAAATCAGAAGCCATGAAAGAGAAACTCCAGACTGAGCTGGCTTCTTTAAAAGTGAATGGACCTTCC
CAGCCCATCCTCGTCAGAGTGGGAGAAGATATACAGCTAACCTGTTACCTGTCCCCCAAGGCGAATGCACAGAGCATGGAGGTGAGGTGG
GACCGATCCCACCGTTACCCTGCTGTGCATGTGTATATGGATGGGGACCATGTGGCTGGAGAGCAGATGGCAGAGTACAGAGGGAGGACT
GTACTGGTGAGTGACGCCATTGACGAGGGCAGACTGACCCTGCAGATACTCAGTGCCAGACCTTCGGACGACGGGCAGTACCGCTGCCTT
TTTGAAAAAGATGATGTCTACCAGGAGGCCAGTTTGGATCTGAAGGTGGTAAGTCTGGGTTCTTCCCCACTGATCACTGTGGAGGGGCAA
GAAGATGGAGAAATGCAGCCGATGTGCTCTTCAGATGGGTGGTTCCCACAGCCCCACGTGCCATGGAGGGACATGGAAGGAAAGACGATA
CCATCATCTTCCCAGGCCCTGACTCAAGGCAGCCACGGGCTGTTCCACGTGCAGACATTGCTAAGGGTCACAAACATCTCCGCTGTGGAC
GTCACTTGTTCCATCAGCATCCCCTTTTTGGGCGAGGAGAAAATCGCAACTTTTTCTCTCTCAGAGTCCAGGATGACGTTTTTGTGGAAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ROCK2_ENST00000315872_chr2_11351807_-_BTNL2_ENST00000454136_chr6_32369582_-_3398nt
CAAGGCGGCCGGCGGCGACCATGGCAGCGGGCCGGCGGCGGCCGTAGTGGCCCAGGCCTGGGCTTCAGCCTCCCGGGGCCCCAGAGGGCG
GGGCGGTCCGGGCCGCGGCGGTGGCGGCGCCACTTCCCTGCTCCCGCCCGAGGACTCCTGCGGGCACTCGCTGAGGACCAGCGGACCGGC
GGCGCGAATCTGACTGAGGGGCGGGGACGCCGTCTGTTCCCCGCCGCTCCCGGCAGGGCCGGGCCGGGCTGGGCCGGGCTGGGCCGGGCG
GGCCCCTGGGAGCAGCCCCCAGGCGGGGGACCGCCTTGGAGACCCGAAGCCGGAGCTAGAGGCAGGCGGTGGGCCCGGGTGGAGTCCCGG
CCGGAGCTGGTGGTTCGGGGGCGGTGCTAGGCCCCGAGGCTGCGGGACCTGAGCGCGAGGAGCCTGAGTGCGGGTCCAGCGGTGGCGGCA
TGAGCCGGCCCCCGCCGACGGGGAAAATGCCCGGCGCCCCCGAGACCGCGCCGGGGGACGGGGCAGGCGCGAGCCGCCAGAGGAAGCTGG
AGGCGCTGATCCGAGACCCTCGCTCCCCCATCAACGTGGAGAGCTTGCTGGATGGCTTAAATTCCTTGGTCCTTGATTTAGATTTTCCTG
CTTTGAGGAAAAACAAGAACATAGATAATTTCTTAAATAGATATGAGAAAATTGTGAAAAAAATCAGAGGTCTACAGATGAAGGCAGAAG
ACTATGATGTTGTAAAAGTTATTGGAAGAGGTGCTTTTGGTGAAGTGCAGTTGGTTCGTCACAAGGCATCGCAGAAGGTTTATGCTATGA
AGCTTCTTAGTAAGTTTGAAATGATAAAAAGATCAGATTCTGCCTTTTTTTGGGAAGAAAGAGATATTATGGCCTTTGCCAATAGCCCCT
GGGTGGTTCAGCTTTTTTATGCCTTTCAAGATGATAGGTATCTGTACATGGTAATGGAGTACATGCCTGGTGGAGACCTTGTAAACCTTA
TGAGTAATTATGATGTGCCTGAAAAATGGGCCAAATTTTACACTGCTGAAGTTGTTCTTGCTCTGGATGCAATACACTCCATGGGTTTAA
TACACAGAGATGTGAAGCCTGACAACATGCTCTTGGATAAACATGGACATCTAAAATTAGCAGATTTTGGCACGTGTATGAAGATGGATG
AAACAGGCATGGTACATTGTGATACAGCAGTTGGAACACCGGATTATATATCACCTGAGGTTCTGAAATCACAAGGGGGTGATGGTTTCT
ATGGGCGAGAATGTGATTGGTGGTCTGTAGGTGTTTTCCTTTATGAGATGCTAGTGGGGGATACTCCATTTTATGCGGATTCACTTGTAG
GAACATATAGCAAAATTATGGATCATAAGAATTCACTGTGTTTCCCTGAAGATGCAGAAATTTCCAAACATGCAAAGAATCTCATCTGTG
CTTTCTTAACAGATAGGGAGGTACGACTTGGGAGAAATGGGGTGGAAGAAATCAGACAGCATCCTTTCTTTAAGAATGATCAGTGGCATT
GGGATAACATAAGAGAAACGGCAGCTCCTGTAGTACCTGAACTCAGCAGTGACATAGACAGCAGCAATTTCGATGACATTGAAGATGACA
AAGGAGATGTAGAAACCTTCCCAATTCCTAAAGCTTTTGTTGGAAATCAGCTGCCTTTCATCGGATTTACCTACTATAGAGAAAATTTAT
TATTAAGTGACTCTCCATCTTGTAGAGAAACTGATTCCATACAATCAAGGAAAAATGAAGAAAGTCAAGAGATTCAGAAAAAACTGTATA
CATTAGAAGAACATCTTAGCAATGAGATGCAAGCCAAAGAGGAACTGGAACAGAAGTGCAAATCTGTTAATACTCGCCTAGAAAAAACAG
CAAAGGAGCTAGAAGAGGAGATTACCTTACGGAAAAGTGTGGAATCAGCATTAAGACAGTTAGAAAGAGAAAAGGCGCTTCTTCAGCACA
AAAATGCAGAATATCAGAGGAAAGCTGATCATGAAGCAGACAAAAAACGAAATTTGGAAAATGATGTTAACAGCTTAAAAGATCAACTTG
AAGATTTGAAAAAAAGAAATCAAAACTCTCAAATATCCACTGAGAAAGTGAATCAACTCCAGAGACAACTGGATGAAACCAATGCTTTAC
TGCGAACAGAGTCTGATACTGCAGCCCGGTTAAGGAAAACCCAGGCAGAAAGTTCAAAACAGATTCAGCAGCTGGAATCTAACAATAGAG
ATCTACAAGATAAAAACTGCCTGCTGGAGACTGCCAAGTTAAAACTTGAAAAGGAATTTATCAATCTTCAGTCAGCTCTAGAATCTGAAA
GGAGGGATCGAACCCATGGATCAGAGATAATTAATGATTTACAAGGTAGAATATGTGGCCTAGAAGAAGATTTAAAGAACGGCAAAATCT
TACTAGCGAAAGTAGAACTGGAGAAGAGACAACTTCAGGAGAGATTTACTGATTTGGAAAAGGAAAAAAGCAACATGGAAATAGATATGA
CATACCAACTAAAAGTTATACAGCAGAGCCTAGAACAAGAAGAAGCTGAACATAAGGCCACAAAGGCACGACTAGCAGATAAAAATAAGA
TCTATGAGTCCATCGAAGAAGCCAAATCAGAAGCCATGAAAGAGAAACTCCAGACTGAGCTGGCTTCTTTAAAAGTGAATGGACCTTCCC
AGCCCATCCTCGTCAGAGTGGGAGAAGATATACAGCTAACCTGTTACCTGTCCCCCAAGGCGAATGCACAGAGCATGGAGGTGAGGTGGG
ACCGATCCCACCGTTACCCTGCTGTGCATGTGTATATGGATGGGGACCATGTGGCTGGAGAGCAGATGGCAGAGTACAGAGGGAGGACTG
TACTGGTGAGTGACGCCATTGACGAGGGCAGACTGACCCTGCAGATACTCAGTGCCAGACCTTCGGACGACGGGCAGTACCGCTGCCTTT
TTGAAAAAGATGATGTCTACCAGGAGGCCAGTTTGGATCTGAAGGTGGTAAGTCTGGGTTCTTCCCCACTGATCACTGTGGAGGGGCAAG
AAGATGGAGAAATGCAGCCGATGTGCTCTTCAGATGGGTGGTTCCCACAGCCCCACGTGCCATGGAGGGACATGGAAGGAAAGACGATAC
CATCATCTTCCCAGGCCCTGACTCAAGGCAGCCACGGGCTGTTCCACGTGCAGACATTGCTAAGGGTCACAAACATCTCCGCTGTGGACG
TCACTTGTTCCATCAGCATCCCCTTTTTGGGCGAGGAGAAAATCGCAACTTTTTCTCTCTCAGAGTCCAGGATGACGTTTTTGTGGAAAA


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FusionGenePPI for ROCK2_BTNL2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ROCK2IKBKE, STK16, RHOA, ELAVL1, MAGEC1, KIAA0196, RABGEF1, FAM21A, GPHN, LMNA, MTA2, NHP2L1, ZW10, DNAJB11, RACGAP1, NTRK1, SNW1, CDC5L, CDKN3, POLR1C, ROCK1, FBXO42, LRPAP1, ADD2, MYL2, LZTFL1, CYLDBTNL2


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-1833373_4207341389NPM1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneROCK2chr2:11351807chr6:32369582ENST00000315872-1833363_7847341389PPP1R12A


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ROCK2_BTNL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ROCK2_BTNL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneBTNL2C0005138Berylliosis1CTD_human